TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 334.367 | Formula: C17H22N2O5
H donors: 3 H acceptors: 4 LogP: 1.5 Rotable bonds: 9
Rule of 5 violations (Lipinski): 1
SMILES: O=C(CNC(=O)C1CCCCC1C(=O)O)NOCc1ccccc1
InChi: 1S/C17H22N2O5/c20-15(19-24-11-12-6-2-1-3-7-12)10-18-16(21)13-8-4-5-9-14(13)17(22)23/h1-3,6-7,13-14H,4-5,8-11H2,(H,18,21)(H,19,20)(H,22,23)
InChiKey: SMCCUIFNXHOLDP-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0065	0.0013	0.0011
Trichomonas vaginalis	AGC family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0202	0.0312	0.031
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0013	0.0013
Schistosoma mansoni	SH2A	0.0063	0.0009	0.0007
Echinococcus granulosus	pro neuregulin 2 membrane bound	0.0065	0.0013	0.0011
Loa Loa (eye worm)	TK/EGFR protein kinase	0.4646	1	1
Loa Loa (eye worm)	hypothetical protein	0.0359	0.0654	0.0654
Loa Loa (eye worm)	hypothetical protein	0.0338	0.0609	0.0609
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Echinococcus multilocularis	epidermal growth factor receptor	0.2525	0.5376	0.5375
Schistosoma mansoni	tyrosine kinase	0.2437	0.5184	0.5184
Loa Loa (eye worm)	TKL/RAF/RAF protein kinase	0.0088	0.0063	0.0063
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Onchocerca volvulus		0.0059	0.0000017733	0.0000039862
Echinococcus granulosus	tyrosine protein kinase ABL1	0.0151	0.0201	0.0199
Entamoeba histolytica	tyrosin kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	ankyrin repeat-containing protein, putative	0.0088	0.0063	0.3445
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Schistosoma mansoni	netrin receptor unc5	0.0065	0.0013	0.0011
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0088	0.0063	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Schistosoma mansoni	septate junction protein	0.0065	0.0013	0.0011
Echinococcus multilocularis	roundabout 2	0.0117	0.0125	0.0124
Loa Loa (eye worm)	TK/FER protein kinase	0.0088	0.0063	0.0063
Loa Loa (eye worm)	TK protein kinase	0.0367	0.0671	0.0671
Brugia malayi	SH2 domain containing protein	0.0151	0.0201	0.0191
Onchocerca volvulus	Netrin receptor homolog	0.0059	0.0000017733	0.0000039862
Brugia malayi	Protein kinase domain containing protein	0.1527	0.32	0.3193
Loa Loa (eye worm)	TKL/MLK/ILK protein kinase	0.0088	0.0063	0.0063
Trichomonas vaginalis	CMGC family protein kinase	0.0141	0.0178	1
Echinococcus multilocularis	proto oncogene tyrosine protein kinase LCK	0.0481	0.0921	0.0919
Loa Loa (eye worm)	TK/EPH protein kinase	0.0163	0.0227	0.0227
Brugia malayi	hypothetical protein	0.0262	0.0442	0.0433
Entamoeba histolytica	protein kinase, putative	0.0193	0.0292	0.4278
Echinococcus granulosus	raf serine:threonine protein kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	nephrin	0.0117	0.0125	0.0124
Brugia malayi	Protein kinase domain containing protein	0.0193	0.0292	0.0283
Echinococcus multilocularis		0.0063	0.0009	0.0007
Echinococcus multilocularis	tyrosine protein kinase Abl	0.0202	0.0312	0.031
Echinococcus granulosus	basic fibroblast growth factor receptor 1 A	0.03	0.0526	0.0524
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Schistosoma mansoni	tyrosine kinase	0.03	0.0526	0.0524
Schistosoma mansoni	eyes absent homolog	0.0087	0.0062	0.006
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus multilocularis	tyrosine kinase	0.0151	0.0201	0.0199
Schistosoma mansoni	tyrosine kinase	0.0151	0.0201	0.0199
Schistosoma mansoni	peroxidasin	0.0065	0.0013	0.0011
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	receptor protein kinase, putative	0.0088	0.0063	0.0808
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0117	0.0125	0.0116
Trypanosoma brucei	kinetoplastid kinetochore protein 10	0.0132	0.0158	0.0535
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Schistosoma mansoni	nephrin	0.0286	0.0496	0.0494
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0481	0.0921	0.0919
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0088	0.0063	0.0063
Echinococcus multilocularis	integrin linked protein kinase	0.0088	0.0063	0.0061
Onchocerca volvulus		0.0061	0.0005	0.0011
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	defective proboscis extension response	0.0235	0.0384	0.0382
Echinococcus multilocularis	peroxidasin	0.0114	0.0121	0.0119
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Onchocerca volvulus		0.0151	0.0201	0.0451
Schistosoma mansoni	cell adhesion molecule	0.0065	0.0013	0.0011
Brugia malayi	Immunoglobulin domain containing protein	0.0065	0.0013	0.0004
Echinococcus granulosus	tyrosine protein kinase csk	0.0088	0.0063	0.0061
Echinococcus multilocularis	epidermal growth factor receptor	0.4646	1	1
Echinococcus multilocularis	cyclin dependent kinase 5	0.0141	0.0178	0.0176
Trichomonas vaginalis	br serine/threonine-protein kinase, putative	0.0088	0.0063	0.3445
Echinococcus multilocularis	tyrosine protein kinase Btk29A	0.0202	0.0312	0.031
Echinococcus multilocularis	lachesin	0.0114	0.0121	0.0119
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Schistosoma mansoni	suppressor of cytokine signaling	0.0063	0.0009	0.0007
Schistosoma mansoni	neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule	0.0114	0.0121	0.0119
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	SH2 domain containing protein	0.0151	0.0201	0.0191
Loa Loa (eye worm)	TK protein kinase	0.043	0.0809	0.0809
Brugia malayi	hypothetical protein	0.0088	0.0063	0.0054
Echinococcus granulosus	cyclin dependent kinase 5 activator 1	0.0547	0.1063	0.1061
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Loa Loa (eye worm)	fructose-1,6-bisphosphatase	0.1402	0.2928	0.2928
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Onchocerca volvulus		0.0151	0.0201	0.0451
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0137	0.0171	0.0171
Entamoeba histolytica	leucine-rich repeat domain-containing protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0121	0.0121
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Echinococcus granulosus	ephrin type A receptor 4 A	0.0161	0.0222	0.022
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0121	0.0121
Echinococcus granulosus	macrophage colony stimulating factor 1 receptor	0.2159	0.4579	0.4578
Echinococcus multilocularis	SH2 domain containing protein 7	0.0063	0.0009	0.0007
Brugia malayi	proto-oncogene tyrosine-protein kinase FER	0.0088	0.0063	0.0054
Brugia malayi	Protein kinase domain containing protein	0.0151	0.0201	0.0191
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	neuroglian	0.0284	0.0491	0.0489
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0114	0.0121	0.0112
Echinococcus multilocularis	raf serine:threonine protein kinase	0.0088	0.0063	0.0061
Brugia malayi	ephrin receptor 1 precursor	0.0116	0.0123	0.0114
Echinococcus granulosus	suppressor of cytokine signaling 6	0.0063	0.0009	0.0007
Echinococcus granulosus	tensin	0.0063	0.0009	0.0007
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0114	0.0121	0.0112
Brugia malayi	Protein kinase domain containing protein	0.0151	0.0201	0.0191
Echinococcus granulosus	SH2 motif	0.0063	0.0009	0.0007
Entamoeba histolytica	ankyrin repeat protein	0.0088	0.0063	0.0808
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	tyrosine kinase	0.2437	0.5184	0.5184
Schistosoma mansoni	serine/threonine protein kinase	0.0141	0.0178	0.0176
Schistosoma mansoni	tyrosine kinase	0.4646	1	1
Loa Loa (eye worm)	TK/KIN6 protein kinase	0.0088	0.0063	0.0063
Schistosoma mansoni	hypothetical protein	0.0065	0.0013	0.0011
Toxoplasma gondii	calcium binding egf domain-containing protein	0.0113	0.0117	0.019
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0088	0.0063	0.0063
Brugia malayi	hypothetical protein	0.0088	0.0063	0.0054
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Schistosoma mansoni	serine/threonine protein kinase	0.0139	0.0175	0.0173
Echinococcus multilocularis	leucine rich repeat containing protein 4	0.0065	0.0013	0.0011
Echinococcus granulosus	fructose 16 bisphosphatase 1	0.1402	0.2928	0.2926
Brugia malayi	hypothetical protein	0.0151	0.0201	0.0191
Toxoplasma gondii	fructose-bisphospatase I	0.0521	0.1008	0.3299
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Onchocerca volvulus		0.0063	0.0009	0.0021
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Onchocerca volvulus		0.0151	0.0201	0.0451
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0342	0.0617	0.0616
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Loa Loa (eye worm)	TK/KIN16 protein kinase	0.234	0.4974	0.4974
Schistosoma mansoni	protein tyrosine kinase	0.0088	0.0063	0.0061
Echinococcus granulosus	mitogen-activated protein kinase kinase kinase 9	0.0088	0.0063	0.0061
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0063	0.0009	0.0007
Echinococcus granulosus	tyrosine protein kinase shark	0.0151	0.0201	0.0199
Echinococcus multilocularis	atrial natriuretic peptide receptor 1	0.0088	0.0063	0.0061
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0088	0.0063	0.0063
Schistosoma mansoni	serine/threonine protein kinase	0.0132	0.0158	0.0156
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	conserved hypothetical protein	0.0088	0.0063	0.3445
Loa Loa (eye worm)	protein-tyrosine phosphatase	0.0063	0.0009	0.0009
Echinococcus granulosus	guanine nucleotide exchange factor VAV2	0.0063	0.0009	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0235	0.0384	0.0384
Loa Loa (eye worm)	hypothetical protein	0.0547	0.1063	0.1063
Onchocerca volvulus		0.0063	0.0009	0.0021
Entamoeba histolytica	protein kinase domain containing protein	0.0091	0.007	0.0922
Onchocerca volvulus		0.0063	0.0009	0.0021
Loa Loa (eye worm)	multiple epidermal growth factor-like domains 6	0.0113	0.0117	0.0117
Echinococcus granulosus	natriuretic peptide receptor 1	0.0088	0.0063	0.0061
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Echinococcus multilocularis	protein KINase family member (kin 25)	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	TK protein kinase	0.0088	0.0063	0.0063
Loa Loa (eye worm)	TK protein kinase	0.0088	0.0063	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0237	0.0388	0.0388
Loa Loa (eye worm)	STAT protein	0.0063	0.0009	0.0009
Loa Loa (eye worm)	TK/ACK protein kinase	0.0088	0.0063	0.0063
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0481	0.0921	0.0919
Schistosoma mansoni	cell adhesion molecule	0.0065	0.0013	0.0011
Schistosoma mansoni	tensin	0.0063	0.0009	0.0007
Onchocerca volvulus		0.0151	0.0201	0.0451
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	protein kinase	0.0088	0.0063	0.0061
Entamoeba histolytica	tyrosin kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus multilocularis	tyrosine protein kinase csk	0.0088	0.0063	0.0061
Brugia malayi	hypothetical protein	0.0087	0.0062	0.0053
Echinococcus granulosus	fibroblast growth factor receptor 4	0.03	0.0526	0.0524
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0481	0.0921	0.0919
Echinococcus multilocularis	receptor type guanylyl cyclase	0.0088	0.0063	0.0061
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Schistosoma mansoni	nck2/grb4	0.0115	0.0121	0.0119
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0121	0.0121
Entamoeba histolytica	cysteine surface protein, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	tyrosine kinase	0.0481	0.0921	0.0919
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0121	0.0121
Echinococcus granulosus	tyrosine protein kinase otk	0.0114	0.0121	0.0119
Entamoeba histolytica	hypothetical protein	0.0193	0.0292	0.4278
Loa Loa (eye worm)	TK/FER protein kinase	0.0088	0.0063	0.0063
Onchocerca volvulus		0.0151	0.0201	0.0451
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0151	0.0201	0.289
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Echinococcus granulosus	tyrosine protein kinase	0.0088	0.0063	0.0061
Entamoeba histolytica	protein kinase with ankyrin repeats, putative	0.0088	0.0063	0.0808
Brugia malayi	Protein kinase domain containing protein	0.0151	0.0201	0.0191
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus multilocularis	tyrosine protein kinase	0.0088	0.0063	0.0061
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0088	0.0063	0.0061
Echinococcus multilocularis	hemicentin 1	0.0124	0.0142	0.014
Trichomonas vaginalis	CMGC family protein kinase	0.0132	0.0158	0.8871
Entamoeba histolytica	tyrosin kinase, putative	0.0088	0.0063	0.0808
Echinococcus multilocularis	pro neuregulin 2, membrane bound	0.0065	0.0013	0.0011
Echinococcus multilocularis	tensin	0.0063	0.0009	0.0007
Brugia malayi	Tyrosine-protein kinase PR2	0.0088	0.0063	0.0054
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Echinococcus multilocularis	fibroblast growth factor receptor 4	0.03	0.0526	0.0524
Loa Loa (eye worm)	TK/FER protein kinase	0.0088	0.0063	0.0063
Echinococcus granulosus	phosphatidylinositol 3 kinase regulatory subunit	0.0151	0.0201	0.0199
Echinococcus multilocularis	protein kinase	0.0088	0.0063	0.0061
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Brugia malayi	Peroxidasin	0.0114	0.0121	0.0112
Trypanosoma cruzi	kinetoplastid kinetochore protein 10, putative	0.0132	0.0158	0.0535
Echinococcus multilocularis	transfer RNA-Thr	0.0088	0.0063	0.0061
Brugia malayi	Calcium binding EGF domain containing protein	0.0113	0.0117	0.0108
Schistosoma mansoni	protein kinase	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus multilocularis	tyrosine protein kinase ABL1	0.0151	0.0201	0.0199
Echinococcus multilocularis	tyrosine protein kinase csk	0.0088	0.0063	0.0061
Echinococcus granulosus	growth factor receptor bound protein 2	0.0115	0.0121	0.0119
Echinococcus multilocularis	Immunoglobulin	0.0065	0.0013	0.0011
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0342	0.0617	0.0616
Loa Loa (eye worm)	CMGC/CDK/CDK5 protein kinase	0.0141	0.0178	0.0178
Loa Loa (eye worm)	hypothetical protein	0.0113	0.0117	0.0117
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0121	0.0121
Echinococcus granulosus	hypothetical protein	0.0128	0.0151	0.0149
Loa Loa (eye worm)	TK/FAK protein kinase	0.0088	0.0063	0.0063
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	TK/RYK protein kinase	0.0088	0.0063	0.0063
Schistosoma mansoni	septate junction protein	0.0114	0.0121	0.0119
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Trypanosoma cruzi	cdc2-related kinase 3	0.0141	0.0178	0.0603
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0117	0.0125	0.0116
Entamoeba histolytica	protein kinase domain containing protein	0.0193	0.0292	0.4278
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	roundabout	0.0114	0.0121	0.0119
Schistosoma mansoni	serine/threonine RGC	0.0088	0.0063	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0101	0.0092	0.0092
Schistosoma mansoni	neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule	0.0065	0.0013	0.0011
Schistosoma mansoni	serine/threonine protein kinase	0.0132	0.0158	0.0156
Schistosoma mansoni	netrin receptor unc5	0.0065	0.0013	0.0011
Trypanosoma cruzi	kinetoplastid kinetochore protein 19, putative	0.0132	0.0158	0.0535
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0065	0.0013	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0013	0.0013
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Echinococcus granulosus	activin receptor type	0.0091	0.007	0.0068
Echinococcus multilocularis	cyclin dependent kinase 5 activator 1	0.0547	0.1063	0.1061
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Toxoplasma gondii	cell-cycle-associated protein kinase CLK, putative	0.0132	0.0158	0.0334
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase src	0.0088	0.0063	0.0061
Echinococcus multilocularis	phosphatidylinositol 3 kinase regulatory subunit	0.0151	0.0201	0.0199
Loa Loa (eye worm)	TK/FER protein kinase	0.0088	0.0063	0.0063
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0141	0.0178	0.0178
Trypanosoma cruzi	protein kinase, putative	0.0088	0.0063	0.0208
Brugia malayi	Immunoglobulin I-set domain containing protein	0.234	0.4974	0.4969
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Loa Loa (eye worm)	hypothetical protein	0.019	0.0285	0.0285
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Echinococcus granulosus	tyrosine kinase	0.0151	0.0201	0.0199
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Trypanosoma brucei	Pseudokinase, putative	0.0088	0.0063	0.0208
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	tyrosine kinase	0.043	0.0809	0.0807
Echinococcus multilocularis	suppressor of cytokine signaling 6	0.0063	0.0009	0.0007
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Onchocerca volvulus		0.0151	0.0201	0.0451
Echinococcus granulosus	tyrosine protein kinase Fps85D	0.0151	0.0201	0.0199
Echinococcus granulosus	tyrosine protein kinase HCK	0.0367	0.0671	0.0669
Onchocerca volvulus		0.0088	0.0063	0.0141
Trichomonas vaginalis	conserved hypothetical protein	0.0088	0.0063	0.3445
Echinococcus granulosus	integrin linked protein kinase	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	fructose-1,6-bisphosphatase	0.1402	0.2928	0.2921
Echinococcus multilocularis	SH2 motif	0.0063	0.0009	0.0007
Echinococcus multilocularis	dual specificity protein kinase clk2	0.0132	0.0158	0.0156
Trichomonas vaginalis	conserved hypothetical protein	0.0088	0.0063	0.3445
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0065	0.0013	0.0004
Schistosoma mansoni	hypothetical protein	0.0061	0.0005	0.0003
Echinococcus granulosus	lachesin	0.0114	0.0121	0.0119
Onchocerca volvulus		0.0088	0.0063	0.0141
Loa Loa (eye worm)	immunoglobulin domain-containing protein	0.0065	0.0013	0.0013
Entamoeba histolytica	hypothetical protein, conserved	0.0088	0.0063	0.0808
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Loa Loa (eye worm)	TK protein kinase	0.0088	0.0063	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Schistosoma mansoni	fructose-16-bisphosphatase-related	0.1402	0.2928	0.2926
Echinococcus granulosus	hemicentin 1	0.0135	0.0167	0.0165
Onchocerca volvulus	Atrial natriuretic peptide receptor 3 homolog	0.0088	0.0063	0.0141
Loa Loa (eye worm)	hypothetical protein	0.0235	0.0384	0.0384
Brugia malayi	basement membrane proteoglycan precursor	0.0065	0.0013	0.0004
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	tyrosine kinase	0.0481	0.0921	0.0919
Trypanosoma brucei	cdc2-related kinase 1	0.0141	0.0178	0.0603
Schistosoma mansoni	septate junction protein	0.0114	0.0121	0.0119
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Brugia malayi	Heparan sulfate	0.0065	0.0013	0.0004
Loa Loa (eye worm)	bone morphogenetic protein 1b	0.0349	0.0633	0.0633
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0013	0.0013
Echinococcus granulosus	Immunoglobulin	0.0065	0.0013	0.0011
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0117	0.0125	0.0124
Entamoeba histolytica	tyrosin kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	nephrin related	0.0065	0.0013	0.0011
Leishmania major	cell division related protein kinase 2,cdc2-related kinase	0.0141	0.0178	0.0603
Echinococcus granulosus	cyclin dependent kinase 5	0.0141	0.0178	0.0176
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0117	0.0125	0.0124
Loa Loa (eye worm)	hypothetical protein	0.0237	0.0388	0.0388
Echinococcus multilocularis	Tolloid protein 1	0.0349	0.0633	0.0631
Brugia malayi	Receptor family ligand binding region containing protein	0.0088	0.0063	0.0054
Echinococcus multilocularis	neurotracting:lsamp:neurotrimin:obcam	0.0114	0.0121	0.0119
Leishmania major	serine/threonine-protein kinase, putative,protein kinase, putative	0.0193	0.0292	0.0993
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0067	0.0018	0.0009
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	TKL/MLK/TAK1 protein kinase	0.0088	0.0063	0.0063
Onchocerca volvulus		0.0063	0.0009	0.0021
Echinococcus granulosus	low density lipoprotein receptor ldl	0.0065	0.0013	0.0011
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Loa Loa (eye worm)	TK protein kinase	0.0088	0.0063	0.0063
Echinococcus multilocularis	signal transduction protein lnk realted	0.0063	0.0009	0.0007
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Trichomonas vaginalis	protein kinase atn1, putative	0.0088	0.0063	0.3445
Echinococcus granulosus	Immunoglobulin	0.0065	0.0013	0.0011
Echinococcus multilocularis	tyrosine protein kinase Fps85D	0.0151	0.0201	0.0199
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0481	0.0921	0.0919
Trypanosoma brucei	CMGC/DYRK protein kinase, putative	0.0193	0.0292	0.0993
Loa Loa (eye worm)	TK/ABL protein kinase	0.0151	0.0201	0.0201
Entamoeba histolytica	SH2-protein kinase domain containing protein	0.0067	0.0017	0.0114
Trichomonas vaginalis	CMGC family protein kinase	0.0141	0.0178	1
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	cyclin dependent kinase	0.0141	0.0178	0.0176
Echinococcus granulosus	SH2 motif	0.0063	0.0009	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Leishmania major		0.1402	0.2928	1
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0063	0.0009	0.0007
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Echinococcus multilocularis	FL cytokine receptor	0.0088	0.0063	0.0061
Echinococcus multilocularis	dual specificity	0.0193	0.0292	0.029
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0121	0.0121
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0088	0.0063	0.0061
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0088	0.0063	0.0061
Echinococcus multilocularis	guanine nucleotide exchange factor VAV2	0.0063	0.0009	0.0007
Toxoplasma gondii	calcium dependent protein kinase CDPK8	0.0091	0.007	0.0026
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Echinococcus granulosus	Immunoglobulin subtype	0.0065	0.0013	0.0011
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Schistosoma mansoni	hypothetical protein	0.0088	0.0063	0.0061
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus multilocularis	macrophage colony stimulating factor 1 receptor	0.0088	0.0063	0.0061
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Echinococcus multilocularis	tyrosine protein kinase pr2	0.0088	0.0063	0.0061
Loa Loa (eye worm)	LAD-2 short isoform	0.0065	0.0013	0.0013
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0062	0.0062
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Onchocerca volvulus		0.0088	0.0063	0.0141
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Schistosoma mansoni	serine/threonine protein kinase	0.0193	0.0292	0.029
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Loa Loa (eye worm)	hypothetical protein	0.019	0.0285	0.0285
Onchocerca volvulus		0.0088	0.0063	0.0141
Echinococcus multilocularis	cyclin dependent kinase 1	0.0141	0.0178	0.0176
Echinococcus multilocularis	dual specificity testis specific protein kinase	0.0091	0.007	0.0068
Entamoeba histolytica	tyrosine- protein kinase 2, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	protein kinase	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	signal transduction protein lnk realted	0.0063	0.0009	0.0007
Echinococcus granulosus	peroxidasin	0.0114	0.0121	0.0119
Trichomonas vaginalis	TK family protein kinase	0.0088	0.0063	0.3445
Echinococcus multilocularis	tyrosine kinase	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	serine/threonine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	tyrosine kinase	0.0202	0.0312	0.031
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0088	0.0063	0.0061
Echinococcus multilocularis	tyrosine protein kinase Src64B	0.0481	0.0921	0.0919
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0065	0.0013	0.0011
Brugia malayi	Tyrosine-protein kinase F09A5.2 in chromosome X, putative	0.0088	0.0063	0.0054
Echinococcus granulosus	3'partial\|tyrosine protein kinase Fgr	0.0481	0.0921	0.0919
Brugia malayi	protein-tyrosine kinase	0.043	0.0809	0.08
Trypanosoma cruzi	cdc2-related kinase 1	0.0141	0.0178	0.0603
Echinococcus multilocularis	tyrosine protein kinase Blk	0.043	0.0809	0.0807
Trichomonas vaginalis	CAMK family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	Raf kinase	0.0088	0.0063	0.0054
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus multilocularis	Down syndrome cell adhesion molecule	0.0067	0.0018	0.0016
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	TK/FER protein kinase	0.0088	0.0063	0.0063
Loa Loa (eye worm)	CMGC/CLK protein kinase	0.0132	0.0158	0.0158
Schistosoma mansoni	basigin related	0.0065	0.0013	0.0011
Brugia malayi	Protein kinase domain containing protein	0.0151	0.0201	0.0191
Loa Loa (eye worm)	TK/Met protein kinase	0.0088	0.0063	0.0063
Schistosoma mansoni	tyrosine kinase	0.0202	0.0312	0.031
Schistosoma mansoni	protein kinase	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	tyrosine protein phosphatase non receptor type	0.0063	0.0009	0.0007
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0117	0.0125	0.0116
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0114	0.0121	0.0112
Echinococcus multilocularis	roundabout 2	0.0351	0.0638	0.0636
Trypanosoma brucei	fructose-1,6-bisphosphatase	0.1402	0.2928	1
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Schistosoma mansoni	proto-oncogene tyrosine-protein kinase abl1	0.0115	0.0121	0.0119
Echinococcus multilocularis	netrin receptor unc 5	0.0065	0.0013	0.0011
Echinococcus multilocularis	tyrosine protein kinase Src42A	0.0481	0.0921	0.0919
Schistosoma mansoni	tensin	0.0063	0.0009	0.0007
Loa Loa (eye worm)	SH2 domain-containing protein	0.0063	0.0009	0.0009
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	suppressor of cytokine signaling	0.0063	0.0009	0.0007
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	cyclin-dependent kinase 5 activator	0.0547	0.1063	0.1061
Echinococcus multilocularis	tyrosine protein kinase Fgr	0.0481	0.0921	0.0919
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0091	0.007	0.0233
Toxoplasma gondii	calcium binding egf domain-containing protein	0.0113	0.0117	0.019
Loa Loa (eye worm)	TKL/MLK/HH498 protein kinase	0.0088	0.0063	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0262	0.0442	0.0442
Onchocerca volvulus	Tyrosine kinase homolog	0.2099	0.4449	1
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0262	0.0442	0.0442
Loa Loa (eye worm)	protein kinase domain-containing protein	0.0088	0.0063	0.0063
Trichomonas vaginalis	conserved hypothetical protein	0.0088	0.0063	0.3445
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	tyrosine protein kinase csk	0.0088	0.0063	0.0061
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Brugia malayi	C-terminal src kinase protein 1	0.0088	0.0063	0.0054
Echinococcus granulosus	roundabout 2	0.0117	0.0125	0.0124
Schistosoma mansoni	hypothetical protein	0.0065	0.0013	0.0011
Schistosoma mansoni	septate junction protein	0.0065	0.0013	0.0011
Echinococcus multilocularis	tyrosine protein kinase lyn tyrosine protein kinase blk	0.0481	0.0921	0.0919
Loa Loa (eye worm)	cytokine inducible SH2-containing protein 5	0.0063	0.0009	0.0009
Plasmodium vivax	protein kinase, putative	0.0092	0.0073	0.0874
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0065	0.0013	0.0004
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	cell division protein kinase 2, putative	0.0141	0.0178	0.2554
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Onchocerca volvulus	Basement membrane proteoglycan homolog	0.0124	0.0142	0.0319
Echinococcus multilocularis	kinase suppressor of Ras 1	0.0088	0.0063	0.0061
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Schistosoma mansoni	serine/threonine protein kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	hypothetical protein	0.0063	0.0009	0.0007
Echinococcus multilocularis	contactin neuroglian septate junction protein	0.0117	0.0125	0.0124
Echinococcus granulosus	protein kinase	0.0088	0.0063	0.0061
Trypanosoma brucei	kinetoplastid kinetochore protein 19	0.0132	0.0158	0.0535
Schistosoma mansoni	basigin related	0.0065	0.0013	0.0011
Brugia malayi	integrin-linked kinase	0.0088	0.0063	0.0054
Echinococcus granulosus	tyrosine protein kinase Btk29A	0.0202	0.0312	0.031
Schistosoma mansoni	tyrosine kinase	0.2525	0.5376	0.5375
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	protein kinase	0.0088	0.0063	0.0061
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	conserved hypothetical protein	0.0088	0.0063	0.3445
Entamoeba histolytica	serine/threonine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	protein kinase	0.0088	0.0063	0.0061
Echinococcus granulosus	atrial natriuretic peptide receptor 1	0.0088	0.0063	0.0061
Loa Loa (eye worm)	TK protein kinase	0.0349	0.0633	0.0633
Loa Loa (eye worm)	hypothetical protein	0.0349	0.0633	0.0633
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Schistosoma mansoni	tyrosine protein kinase	0.0088	0.0063	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0128	0.0151	0.0151
Onchocerca volvulus	Suppressor of cytokine signaling at 36E homolog	0.0063	0.0009	0.0021
Entamoeba histolytica	protein kinase, putative	0.0067	0.0017	0.0114
Echinococcus multilocularis	neuroglian	0.0284	0.0491	0.0489
Loa Loa (eye worm)	CMGC/DYRK/DYRK1 protein kinase	0.0193	0.0292	0.0292
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Echinococcus granulosus	tyrosine protein kinase Srms	0.0151	0.0201	0.0199
Brugia malayi	Immunoglobulin domain containing protein	0.0065	0.0013	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0151	0.0201	0.0201
Trichomonas vaginalis	STE family protein kinase	0.0088	0.0063	0.3445
Plasmodium falciparum	protein serine/threonine kinase-1	0.0132	0.0158	0.8277
Loa Loa (eye worm)	TKL/STKR/TYPE1 protein kinase	0.0088	0.0063	0.0063
Giardia lamblia	Kinase, CMGC CDK	0.0141	0.0178	1
Schistosoma mansoni	titin	0.0135	0.0167	0.0165
Echinococcus multilocularis	cell adhesion molecule:down regulated by	0.0065	0.0013	0.0011
Schistosoma mansoni	protein kinase	0.0091	0.007	0.0068
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	vesicular amine transporter	0.0235	0.0384	0.0382
Schistosoma mansoni	tyrosine-protein kinase zap-70	0.0063	0.0009	0.0007
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Schistosoma mansoni	ephrin receptor	0.0147	0.0191	0.0189
Toxoplasma gondii	fructose-bisphospatase II	0.1402	0.2928	1
Schistosoma mansoni	egf-like domain protein	0.0101	0.0092	0.009
Leishmania major	hypothetical protein, conserved	0.0088	0.0063	0.0208
Echinococcus multilocularis	protein kinase	0.0088	0.0063	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Loa Loa (eye worm)	hypothetical protein	0.0087	0.0062	0.0062
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0117	0.0125	0.0125
Schistosoma mansoni	hypothetical protein	0.0088	0.0064	0.0062
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Schistosoma mansoni	growth factor receptor-bound protein	0.0115	0.0121	0.0119
Echinococcus granulosus	tyrosine protein kinase transmembrane receptor	0.0137	0.017	0.0168
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Schistosoma mansoni	tyrosine protein kinase fes (fps) (ptk group IV)	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	adapter molecule crk	0.0115	0.0121	0.0119
Brugia malayi	hypothetical protein	0.0237	0.0388	0.038
Echinococcus granulosus	tyrosine protein kinase Src42A	0.0481	0.0921	0.0919
Brugia malayi	Prion-like-	0.0114	0.0121	0.0112
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	serine/threonine protein kinase	0.0088	0.0063	0.0061
Loa Loa (eye worm)	CMGC/CDK/CDC2 protein kinase	0.0141	0.0178	0.0178
Echinococcus granulosus	protein tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	low-density lipoprotein receptor (ldl)	0.0075	0.0034	0.0032
Brugia malayi	SH2 domain containing protein	0.0425	0.0798	0.079
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0063	0.0009	0.0007
Entamoeba histolytica	serine/threonine kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	Protein kinase domain containing protein	0.0151	0.0201	0.0191
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0088	0.0063	0.0054
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0063	0.0009	0.0007
Loa Loa (eye worm)	RGC/RGC protein kinase	0.0088	0.0063	0.0063
Schistosoma mansoni	hypothetical protein	0.0063	0.0009	0.0007
Loa Loa (eye worm)	serine/threonine protein kinase	0.0088	0.0063	0.0063
Trypanosoma brucei	protein kinase, putative	0.0091	0.007	0.0233
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Onchocerca volvulus	Arrow homolog	0.0101	0.0092	0.0207
Echinococcus granulosus	tyrosine kinase\|tyrosine protein kinase Fyn	0.043	0.0809	0.0807
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Trypanosoma cruzi	CMGC/DYRK protein kinase, putative	0.0193	0.0292	0.0993
Echinococcus multilocularis	SH2 motif	0.0063	0.0009	0.0007
Loa Loa (eye worm)	TK/INSR protein kinase	0.1527	0.32	0.32
Echinococcus multilocularis	expressed conserved protein	0.0088	0.0064	0.0062
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	protein tyrosine phosphatase n11 (shp2)	0.0063	0.0009	0.0007
Trypanosoma cruzi	sedoheptulose-1,7-bisphosphatase, putative	0.0521	0.1008	0.3439
Echinococcus granulosus	hypothetical protein	0.0063	0.0009	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0335	0.0602	0.0602
Echinococcus granulosus	tyrosine protein kinase csk	0.0088	0.0063	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0142	0.0182	0.0182
Schistosoma mansoni	tyrosine kinase	0.2437	0.5184	0.5184
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Brugia malayi	Probable tyrosine-protein kinase kin-31	0.0088	0.0063	0.0054
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0088	0.0063	0.0061
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.043	0.0809	0.0807
Echinococcus multilocularis		0.0128	0.0151	0.0149
Entamoeba histolytica	serine/threonine kinase, putative	0.0088	0.0063	0.0808
Trypanosoma cruzi	cdc2-related kinase 3	0.0141	0.0178	0.0603
Loa Loa (eye worm)	hypothetical protein	0.03	0.0525	0.0525
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Onchocerca volvulus		0.0063	0.0009	0.0021
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0117	0.0125	0.0124
Echinococcus multilocularis	fibrillin 1	0.0113	0.0117	0.0115
Echinococcus granulosus	expressed conserved protein	0.0063	0.0009	0.0007
Echinococcus granulosus	proto oncogene tyrosine protein kinase LCK	0.0481	0.0921	0.0919
Schistosoma mansoni	tensin-related	0.0063	0.0009	0.0007
Echinococcus multilocularis	tensin	0.0063	0.0009	0.0007
Schistosoma mansoni	tyrosine kinase	0.2525	0.5376	0.5375
Echinococcus granulosus	expressed conserved protein	0.0088	0.0064	0.0062
Trypanosoma cruzi	fructose-1,6-bisphosphatase, cytosolic, putative	0.1402	0.2928	1
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	TK/FER protein kinase	0.0088	0.0063	0.0063
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	protein kinase, putative	0.0193	0.0292	0.4278
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	tensin-related	0.0063	0.0009	0.0007
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0115	0.0121	0.0121
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Giardia lamblia	Kinase, CMGC CLK	0.0132	0.0158	0.8277
Schistosoma mansoni	serine/threonine protein kinase	0.0088	0.0063	0.0061
Echinococcus granulosus	tyrosine protein kinase Lyn	0.0485	0.0928	0.0926
Entamoeba histolytica	receptor protein kinase, putative	0.0088	0.0063	0.0808
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Echinococcus granulosus	dual specificity testis-specific protein kinase	0.0091	0.007	0.0068
Trypanosoma cruzi	protein kinase, putative	0.0088	0.0063	0.0208
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Loa Loa (eye worm)	TK protein kinase	0.0088	0.0063	0.0063
Trypanosoma cruzi	kinetoplastid kinetochore protein 19, putative	0.0132	0.0158	0.0535
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0114	0.0121	0.0121
Echinococcus multilocularis	tyrosine protein kinase Srms	0.043	0.0809	0.0807
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	cell division protein kinase 2, putative	0.0141	0.0178	0.2554
Echinococcus multilocularis	basement membrane specific heparan sulfate	0.0235	0.0384	0.0382
Echinococcus multilocularis	suppressor of cytokine signaling 7	0.0063	0.0009	0.0007
Loa Loa (eye worm)	TK protein kinase	0.0088	0.0063	0.0063
Schistosoma mansoni	src-type protein tyrosine kinase-related	0.0088	0.0063	0.0061
Echinococcus granulosus	neurotracting:lsamp:neurotrimin:obcam	0.03	0.0525	0.0524
Loa Loa (eye worm)	SH2 domain-containing protein	0.0063	0.0009	0.0009
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0063	0.0009	0.0009
Echinococcus granulosus	basement membrane specific heparan sulfate	0.0065	0.0013	0.0011
Schistosoma mansoni	cell adhesion molecule	0.0117	0.0125	0.0124
Onchocerca volvulus		0.0063	0.0009	0.0021
Trypanosoma cruzi	sedoheptulose-1,7-bisphosphatase, putative	0.0521	0.1008	0.3439
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	chimerin-related rho-gtpase-activating protein	0.0063	0.0009	0.0007
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	TK/CSK protein kinase	0.0088	0.0063	0.0063
Echinococcus granulosus	tensin C1 domain containing phosphatase	0.0063	0.0009	0.0007
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0065	0.0013	0.0004
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Trypanosoma brucei	cdc2-related kinase 3	0.0141	0.0178	0.0603
Echinococcus granulosus	mitogen activated protein kinase kinase kinase	0.0088	0.0063	0.0061
Echinococcus granulosus	laminin	0.0113	0.0117	0.0115
Plasmodium falciparum	protein kinase, putative	0.0091	0.007	0.0651
Loa Loa (eye worm)	AStacin protease	0.0218	0.0348	0.0348
Schistosoma mansoni	cell adhesion molecule	0.0117	0.0125	0.0124
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	low-density lipoprotein receptor repeat class B containing protein	0.0101	0.0092	0.0092
Echinococcus multilocularis	ephrin type A receptor 4 A	0.0161	0.0222	0.022
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Echinococcus granulosus	activated cdc42 kinase 1	0.0088	0.0063	0.0061
Loa Loa (eye worm)	sex muscle abnormal protein 5	0.0115	0.0121	0.0121
Schistosoma mansoni	subfamily M12A unassigned peptidase (M12 family)	0.0349	0.0633	0.0631
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	twitchin	0.0288	0.0498	0.0497
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0088	0.0063	0.0061
Echinococcus granulosus	roundabout 2	0.0117	0.0125	0.0124
Brugia malayi	Guanylyl cyclase protein 23	0.0088	0.0063	0.0054
Toxoplasma gondii	cell-cycle-associated protein kinase CDK, putative	0.0141	0.0178	0.0403
Echinococcus multilocularis	tyrosine protein kinase shark	0.0151	0.0201	0.0199
Echinococcus multilocularis	tyrosine protein kinase transmembrane receptor	0.0137	0.017	0.0168
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0117	0.0125	0.0124
Echinococcus granulosus	neuroglian	0.0117	0.0125	0.0124
Echinococcus multilocularis	fructose 1,6 bisphosphatase 1	0.1402	0.2928	0.2926
Echinococcus granulosus	contactin	0.0126	0.0147	0.0145
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	CAMK/MLCK protein kinase	0.012	0.0133	0.0133
Leishmania major	protein kinase, putative	0.0132	0.0158	0.0535
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0013	0.0013
Onchocerca volvulus		0.0088	0.0063	0.0141
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	GTPase activating protein	0.0063	0.0009	0.0007
Brugia malayi	Variant SH3 domain containing protein	0.0115	0.0121	0.0112
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	TK/ALK protein kinase	0.033	0.0591	0.0591
Brugia malayi	Low-density lipoprotein receptor repeat class B containing protein	0.0101	0.0092	0.0083
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	suppressor of cytokine signaling 7	0.0063	0.0009	0.0007
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	SRC-1	0.0481	0.0921	0.0921
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Brugia malayi	Sex muscle abnormal protein 5	0.0115	0.0121	0.0112
Echinococcus multilocularis	insulin growth factor 1 receptor beta	0.1529	0.3204	0.3203
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Echinococcus multilocularis	tyrosine protein kinase otk	0.0114	0.0121	0.0119
Schistosoma mansoni	protein kinase	0.0091	0.007	0.0068
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0067	0.0018	0.0018
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0115	0.0121	0.0121
Echinococcus granulosus	tyrosine protein kinase Fyn	0.0481	0.0921	0.0919
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Echinococcus granulosus	3'partial\|retinal guanylyl cyclase 2	0.0088	0.0063	0.0061
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Echinococcus multilocularis	tyrosine protein kinase csk	0.0088	0.0063	0.0061
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	CMGC family protein kinase	0.0141	0.0178	1
Echinococcus multilocularis	Immunoglobulin	0.0065	0.0013	0.0011
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Echinococcus granulosus	c src tyrosine kinase	0.0202	0.0312	0.031
Trypanosoma brucei	AGC/RSK family serine/threonine kinase, putative	0.0088	0.0063	0.0208
Echinococcus multilocularis	heat shock protein 70	0.0088	0.0063	0.0061
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	protein kinase	0.0091	0.007	0.0068
Onchocerca volvulus		0.0088	0.0063	0.0141
Brugia malayi	Tyrosine-protein kinase abl-1	0.0202	0.0312	0.0303
Echinococcus multilocularis	roundabout 2	0.0117	0.0125	0.0124
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	activated cdc42 kinase 1	0.0088	0.0063	0.0061
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	hypothetical protein	0.0114	0.0121	0.0121
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Echinococcus granulosus	tyrosine protein kinase pr2	0.0088	0.0063	0.0061
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Echinococcus granulosus	SHC transforming protein 3	0.0063	0.0009	0.0007
Loa Loa (eye worm)	RhoGAP domain-containing protein	0.0063	0.0009	0.0009
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Echinococcus multilocularis	growth factor receptor bound protein 2	0.0115	0.0121	0.0119
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Onchocerca volvulus		0.0088	0.0063	0.0141
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Loa Loa (eye worm)	hypothetical protein	0.0117	0.0125	0.0125
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0117	0.0125	0.0124
Loa Loa (eye worm)	TKL/RAF/KSR protein kinase	0.0088	0.0063	0.0063
Trichomonas vaginalis	serine/threonine-protein kinase wnk, putative	0.0088	0.0063	0.3445
Echinococcus granulosus	tyrosine protein kinase Blk	0.043	0.0809	0.0807
Echinococcus granulosus	5'partial\|cyclin dependent kinase 1	0.0141	0.0178	0.0176
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	cell division control protein 2 homolog	0.0141	0.0178	0.0169
Entamoeba histolytica	serine/threonine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	tyrosine kinase	0.1527	0.32	0.3198
Echinococcus multilocularis		0.1419	0.2965	0.2963
Echinococcus granulosus	Down syndrome cell adhesion molecule	0.0067	0.0018	0.0016
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	hypothetical protein	0.0235	0.0384	0.0384
Echinococcus multilocularis	basic fibroblast growth factor receptor 1 A	0.03	0.0526	0.0524
Echinococcus multilocularis	cyclin dependent kinase 1	0.0141	0.0178	0.0176
Echinococcus multilocularis	activin receptor type	0.0091	0.007	0.0068
Echinococcus granulosus	NCK adaptor protein	0.0115	0.0121	0.0119
Onchocerca volvulus	Tyrosine kinase receptor Cad96Ca homolog	0.0088	0.0063	0.0141
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Echinococcus granulosus	SH2 domain containing protein 7	0.0063	0.0009	0.0007
Onchocerca volvulus		0.0088	0.0063	0.0141
Schistosoma mansoni	cell adhesion molecule	0.0114	0.0121	0.0119
Schistosoma mansoni	hypothetical protein	0.0065	0.0013	0.0011
Loa Loa (eye worm)	TK/FER protein kinase	0.0151	0.0201	0.0201
Trypanosoma cruzi	kinetoplastid kinetochore protein 10, putative	0.0132	0.0158	0.0535
Echinococcus granulosus	N chimaerin	0.0063	0.0009	0.0007
Echinococcus multilocularis	insulin receptor	0.1527	0.32	0.3198
Leishmania major	protein kinase, putative	0.0132	0.0158	0.0535
Echinococcus granulosus	dual specificity protein kinase clk2	0.0132	0.0158	0.0156
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0065	0.0013	0.0004
Loa Loa (eye worm)	hypothetical protein	0.0425	0.0798	0.0798
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0237	0.0388	0.038
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Brugia malayi	Protein kinase domain containing protein	0.033	0.0591	0.0582
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0114	0.0121	0.0112
Echinococcus multilocularis	N chimaerin	0.0063	0.0009	0.0007
Brugia malayi	bone morphogenetic protein type 1 receptor	0.0088	0.0063	0.0054
Echinococcus granulosus	3'partial\|cell adhesion molecule:down regulated by	0.0065	0.0013	0.0011
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0088	0.0063	0.0061
Loa Loa (eye worm)	TK/DDR protein kinase	0.0088	0.0063	0.0063
Trichomonas vaginalis	protein tyrosine kinase, putative	0.0088	0.0063	0.3445
Echinococcus multilocularis	Immunoglobulin	0.0235	0.0384	0.0382
Echinococcus multilocularis	tyrosine protein kinase HCK	0.0367	0.0671	0.0669
Entamoeba histolytica	ankyrin repeat protein	0.0088	0.0063	0.0808
Echinococcus granulosus	receptor type guanylyl cyclase	0.0088	0.0063	0.0061
Echinococcus multilocularis	SHC transforming protein 3	0.0063	0.0009	0.0007
Leishmania major	protein kinase, putative	0.0088	0.0063	0.0208
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Trypanosoma cruzi	STE/STE11 serine/threonine-protein kinase, putative	0.0091	0.007	0.0233
Schistosoma mansoni	hypothetical protein	0.0065	0.0013	0.0011
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Onchocerca volvulus	Putative titin	0.0059	0.0000017733	0.0000039862
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	protein kinase	0.0088	0.0063	0.0061
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Echinococcus multilocularis	retinal guanylyl cyclase 2	0.0088	0.0063	0.0061
Echinococcus multilocularis	tyrosine protein kinase csk	0.0088	0.0063	0.0061
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Trichomonas vaginalis	conserved hypothetical protein	0.0088	0.0063	0.3445
Brugia malayi	Variant SH3 domain containing protein	0.0115	0.0121	0.0112
Brugia malayi	Fibulin-1 precursor	0.0113	0.0117	0.0108
Echinococcus granulosus	dual specificity	0.0193	0.0292	0.029
Brugia malayi	Fibronectin type III domain containing protein	0.0237	0.0388	0.038
Echinococcus granulosus	insulin receptor	0.1527	0.32	0.3198
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Entamoeba histolytica	serine/threonine kinase, putative	0.0088	0.0063	0.0808
Schistosoma mansoni	ephrin receptor	0.009	0.0068	0.0066
Schistosoma mansoni	tyrosine-protein kinase fps85d	0.0088	0.0063	0.0061
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Echinococcus multilocularis	activated cdc42 kinase 1	0.0088	0.0063	0.0061
Loa Loa (eye worm)	SH2 domain-containing protein	0.0063	0.0009	0.0009
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Echinococcus multilocularis	NCK adaptor protein	0.0115	0.0121	0.0119
Echinococcus granulosus	epidermal growth factor receptor	0.4646	1	1
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Trypanosoma brucei	sedoheptulose-1,7-bisphosphatase	0.0521	0.1008	0.3439
Loa Loa (eye worm)	TK protein kinase	0.0088	0.0063	0.0063
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Echinococcus multilocularis	natriuretic peptide receptor 1	0.0088	0.0063	0.0061
Brugia malayi	basement membrane proteoglycan	0.0065	0.0013	0.0004
Trypanosoma cruzi	CMGC/DYRK protein kinase, putative	0.0193	0.0292	0.0993
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0349	0.0633	0.0625
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Echinococcus multilocularis	hemicentin 1	0.0126	0.0145	0.0143
Echinococcus multilocularis	tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase	0.0481	0.0921	0.0919
Echinococcus multilocularis	tyrosine protein kinase Fyn	0.0481	0.0921	0.0919
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0114	0.0121	0.0121
Echinococcus multilocularis	laminin	0.0113	0.0117	0.0115
Schistosoma mansoni	tyrosine kinase	0.0088	0.0063	0.0061
Echinococcus granulosus	tyrosine protein kinase Fes:Fps	0.0088	0.0063	0.0061
Brugia malayi	SRC-1	0.0481	0.0921	0.0912
Toxoplasma gondii	sedoheptulose-1,7-bisphosphatase	0.0521	0.1008	0.3299
Echinococcus granulosus	tyrosine kinase	0.0088	0.0063	0.0061
Onchocerca volvulus		0.0088	0.0063	0.0141
Echinococcus granulosus	tyrosine protein kinase Src64B	0.0481	0.0921	0.0919
Trypanosoma cruzi	cdc2-related kinase 1	0.0141	0.0178	0.0603
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0114	0.0121	0.0112
Schistosoma mansoni	tyrosine kinase	0.0151	0.0201	0.0199
Brugia malayi	Protein kinase domain containing protein	0.0132	0.0158	0.0149
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Schistosoma mansoni	serine/threonine protein kinase	0.0141	0.0178	0.0176
Trypanosoma brucei	STE/STE11 serine/threonine-protein kinase, putative	0.0091	0.007	0.0233
Schistosoma mansoni	hypothetical protein	0.0065	0.0013	0.0011
Echinococcus granulosus	melanoma receptor tyrosine protein kinase	0.2525	0.5376	0.5375
Echinococcus granulosus	insulin growth factor 1 receptor beta	0.1529	0.3204	0.3203
Echinococcus granulosus	epidermal growth factor receptor	0.2525	0.5376	0.5375
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	signal transduction protein lnk-related	0.0063	0.0009	0.0007
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	kinase suppressor of Ras 1	0.0088	0.0063	0.0061
Echinococcus granulosus	netrin receptor unc 5	0.0065	0.0013	0.0011
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Trichomonas vaginalis	serine-threonine protein kinase, putative	0.0088	0.0063	0.3445
Schistosoma mansoni	tyrosine kinase	0.0202	0.0312	0.031
Schistosoma mansoni	neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule	0.0065	0.0013	0.0011
Schistosoma mansoni	tyrosine kinase	0.1527	0.32	0.3198
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0088	0.0063	0.0054
Loa Loa (eye worm)	hypothetical protein	0.0063	0.0009	0.0009
Leishmania major	cell division protein kinase 2,cdc2-related kinase	0.0141	0.0178	0.0603
Entamoeba histolytica	protein tyrosine kinase domain-containing protein	0.0088	0.0063	0.0808
Trichomonas vaginalis	conserved hypothetical protein	0.0088	0.0063	0.3445
Echinococcus multilocularis	SH2 motif	0.0063	0.0009	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Trypanosoma cruzi	fructose-1,6-bisphosphatase, cytosolic, putative	0.1402	0.2928	1
Echinococcus granulosus	cyclin dependent kinase 1	0.0141	0.0178	0.0176
Echinococcus granulosus	Tolloid protein 1	0.0349	0.0633	0.0631
Schistosoma mansoni	basigin related	0.0065	0.0013	0.0011
Brugia malayi	Protein kinase domain containing protein	0.0088	0.0063	0.0054
Plasmodium vivax	protein kinase Crk2	0.0141	0.0178	1
Echinococcus granulosus	Immunoglobulin	0.0235	0.0384	0.0382
Echinococcus granulosus	retinal guanylyl cyclase 2	0.0088	0.0063	0.0061
Leishmania major	protein kinase, putative	0.0091	0.007	0.0233
Brugia malayi	Immunoglobulin domain containing protein	0.0065	0.0013	0.0004
Echinococcus multilocularis	low density lipoprotein receptor (ldl)	0.0065	0.0013	0.0011
Echinococcus multilocularis	c src tyrosine kinase	0.0202	0.0312	0.031
Schistosoma mansoni	Neurotrimin precursor (hNT)	0.0235	0.0384	0.0382
Schistosoma mansoni	defective proboscis extension response (dpr)-related	0.0235	0.0384	0.0382
Brugia malayi	Adenylate and Guanylate cyclase catalytic domain containing protein	0.0088	0.0063	0.0054
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0114	0.0121	0.0112
Schistosoma mansoni	tensin	0.0063	0.0009	0.0007
Echinococcus multilocularis	tyrosine protein phosphatase non receptor type	0.0063	0.0009	0.0007
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Echinococcus granulosus	SH2 domain containing adapter protein F	0.0063	0.0009	0.0007
Entamoeba histolytica	protein kinase domain containing protein	0.0088	0.0063	0.0808
Onchocerca volvulus	Suppressor of cytokine signaling 7 homolog	0.0063	0.0009	0.0021
Echinococcus multilocularis	Immunoglobulin subtype	0.0065	0.0013	0.0011
Plasmodium vivax	serine/threonine kinase-1, putative	0.0132	0.0158	0.8277
Schistosoma mansoni	protein kinase	0.0088	0.0063	0.0061
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Trichomonas vaginalis	TKL family protein kinase	0.0088	0.0063	0.3445
Schistosoma mansoni	vav2	0.0063	0.0009	0.0007
Schistosoma mansoni	hypothetical protein	0.0065	0.0013	0.0011
Giardia lamblia	Kinase, CMGC CDK	0.0141	0.0178	1
Schistosoma mansoni	shc transforming protein	0.0063	0.0009	0.0007
Loa Loa (eye worm)	hypothetical protein	0.0088	0.0063	0.0063
Echinococcus multilocularis	Immunoglobulin	0.0235	0.0384	0.0382
Loa Loa (eye worm)	hypothetical protein	0.0213	0.0336	0.0336
Loa Loa (eye worm)	hypothetical protein	0.0065	0.0013	0.0013
Onchocerca volvulus		0.1953	0.4129	0.9281
Echinococcus multilocularis	cyclin dependent kinase	0.0141	0.0178	0.0176
Entamoeba histolytica	protein kinase, putative	0.0367	0.0671	1
Brugia malayi	Protein kinase domain containing protein	0.0141	0.0178	0.0169
Entamoeba histolytica	protein kinase, putative	0.0088	0.0063	0.0808
Trypanosoma brucei	Flagellum attachment zone protein 20	0.0088	0.0063	0.0208
Echinococcus granulosus	roundabout 2	0.0351	0.0638	0.0636
Loa Loa (eye worm)	TK/FER protein kinase	0.0088	0.0063	0.0063
Loa Loa (eye worm)	TK/ROR protein kinase	0.0137	0.017	0.017
Entamoeba histolytica	hypothetical protein	0.0088	0.0063	0.0808
Schistosoma mansoni	growth factor receptor-bound protein	0.0115	0.0121	0.0119
Echinococcus multilocularis	SH2 domain containing adapter protein F	0.0063	0.0009	0.0007
Schistosoma mansoni	neuroglian	0.0117	0.0125	0.0124
Plasmodium falciparum	protein kinase 5	0.0141	0.0178	1
Echinococcus multilocularis	protein tyrosine kinase	0.0088	0.0063	0.0061
Schistosoma mansoni	cell adhesion molecule	0.0302	0.053	0.0528
Entamoeba histolytica	tyrosine kinase, putative	0.0088	0.0063	0.0808
Brugia malayi	hypothetical protein	0.0075	0.0034	0.0025
Echinococcus multilocularis	tyrosine protein kinase Fes:Fps	0.0088	0.0063	0.0061
Echinococcus multilocularis	neuroglian	0.0117	0.0125	0.0124
Echinococcus multilocularis	mitogen activated protein kinase kinase kinase	0.0088	0.0063	0.0061

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (binding)	> 150 uM	In vitro inhibitory activity against rat serum angiotensin I converting enzyme using hippurylglycylglycine as substrate	ChEMBL.	8459398
IC50 (binding)	> 150 uM	In vitro inhibitory activity against rat serum angiotensin I converting enzyme using hippurylglycylglycine as substrate	ChEMBL.	8459398

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

No external resources registered for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 275867