Detailed information for compound 31944

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 433.889 | Formula: C19H18ClN4O4S+
  • H donors: 3 H acceptors: 2 LogP: 2.95 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccccc1)Nc1ccc2c(c1)c(=O)oc(c2Cl)OCCSC(=[NH2+])N
  • InChi: 1S/C19H17ClN4O4S/c20-15-13-7-6-12(24-19(26)23-11-4-2-1-3-5-11)10-14(13)16(25)28-17(15)27-8-9-29-18(21)22/h1-7,10H,8-9H2,(H3,21,22)(H2,23,24,26)/p+1
  • InChiKey: FIVWBAALLYBTLM-UHFFFAOYSA-O  


Substructure search Similarity search

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0016 0.0016
Schistosoma mansoni tyrosine kinase 0.0016 0.0024 0.004
Echinococcus granulosus fmrfamide receptor 0.0013 0.0013 0.0021
Entamoeba histolytica Pten 3-phosphoinositide phosphatase, putative 0.0074 0.0256 0.0644
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0074 0.0256 0.0427
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0148 0.0372
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0016 0.0026
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0148 0.0247
Brugia malayi MH1 domain containing protein 0.0018 0.003 0.0051
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0047 0.0148 0.0247
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0563 0.2209 0.3677
Loa Loa (eye worm) TK/ABL protein kinase 0.0016 0.0024 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0016 0.0091
Schistosoma mansoni amine GPCR 0.0013 0.0013 0.0021
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0013 0.0013 0.0021
Echinococcus granulosus Glycosyl transferase family 35 0.1007 0.3978 0.6623
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0215 0.0358
Onchocerca volvulus 0.0016 0.0024 0.006
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0023 0.0039
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0531 0.0883
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0016 0.0024 0.004
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0101 0.0593
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0024 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0013 0.0013
Brugia malayi Dual specificity protein phosphatase CDC14B 0.0074 0.0256 0.0427
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.0024 0.004
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0085 0.0085
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0075 0.2945
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0016 0.0039
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0014 0.0016 0.0091
Onchocerca volvulus 0.0013 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0431 0.1679 0.2796
Brugia malayi Tachykinin-like peptides receptor 99D 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0043 0.0132 0.0219
Echinococcus granulosus growth factor receptor bound protein 2 0.0016 0.0024 0.004
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0059 0.0149
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0023 0.0023
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0148 0.0873
Schistosoma mansoni hypothetical protein 0.0041 0.0124 0.0207
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0059 0.0149
Echinococcus granulosus somatostatin receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) Smad1 0.0018 0.003 0.0051
Onchocerca volvulus 0.0074 0.0256 0.0644
Echinococcus granulosus snurportin 1 0.0308 0.1189 0.198
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0215 0.0358
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0013 0.0013
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0027 0.0066 0.2475
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0061 0.0205 0.0205
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0013 0.0013
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0016 0.0024 0.004
Onchocerca volvulus 0.0013 0.0013 0.0032
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0268 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0016 0.0024 0.0024
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0016 0.0385
Onchocerca volvulus 0.0074 0.0256 0.0644
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0059 0.1468
Brugia malayi neuropeptide F receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0026
Onchocerca volvulus 0.0016 0.0024 0.006
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0016 0.0045
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0101 0.3762
Toxoplasma gondii aldehyde dehydrogenase 0.0061 0.0205 0.7649
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0066 0.2475
Echinococcus granulosus tyrosine protein kinase Lyn 0.0016 0.0024 0.004
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0074 0.0256 0.0644
Echinococcus multilocularis SH2 motif 0.0016 0.0024 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0093 0.0504
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Brugia malayi Tyrosine-protein kinase abl-1 0.0016 0.0024 0.004
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0162 0.0911
Echinococcus multilocularis somatostatin receptor 0.0013 0.0013 0.0013
Echinococcus multilocularis c src tyrosine kinase 0.0016 0.0024 0.0024
Onchocerca volvulus 0.0013 0.0013 0.0032
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0045 0.0045
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0074 0.0256 0.0427
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0013 0.0014 0.0023
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0148 0.3419
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Echinococcus multilocularis tensin 0.0016 0.0024 0.0024
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.001 0.00000034419 0.00000086519
Echinococcus granulosus SH2 domain containing protein 7 0.0016 0.0024 0.004
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0016 0.0026
Echinococcus multilocularis neuropeptide FF receptor 2 0.0013 0.0013 0.0013
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0016 0.0045
Echinococcus multilocularis roundabout 2 0.0013 0.0014 0.0014
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0014 0.0016 0.0091
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0016 0.0045
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0148 0.0873
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0016 0.0024 0.004
Onchocerca volvulus 0.0074 0.0256 0.0644
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Echinococcus granulosus tyrosine protein kinase Srms 0.0016 0.0024 0.004
Loa Loa (eye worm) RNA binding protein 0.0064 0.0215 0.0358
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0101 0.3762
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0013 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0016 0.0024 0.0024
Schistosoma mansoni nephrin 0.0013 0.0014 0.0023
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0357 0.0594
Schistosoma mansoni glycogen phosphorylase 0.0435 0.1698 0.2826
Loa Loa (eye worm) hypothetical protein 0.032 0.1236 0.2058
Echinococcus granulosus NCK adaptor protein 0.0016 0.0024 0.004
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0054 0.0135
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0215 0.0358
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0024 0.004
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0101 0.0253
Brugia malayi ORL1-like opioid receptor 0.0013 0.0013 0.0021
Schistosoma mansoni cellular tumor antigen P53 0.0054 0.0176 0.0293
Schistosoma mansoni ran 0.0021 0.0045 0.0075
Echinococcus granulosus roundabout 2 0.0013 0.0014 0.0023
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0016 0.0605
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0081 0.0286 0.0286
Echinococcus multilocularis glycogen phosphorylase 0.1007 0.3978 0.3978
Echinococcus granulosus roundabout 2 0.0013 0.0014 0.0023
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0205 0.0341
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0013 0.0013 0.0021
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0013 0.0013 0.0021
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0074 0.0256 0.0427
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0054 0.1331
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0081 0.0286 0.0476
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0215 0.0358
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni cell adhesion molecule 0.0013 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0081 0.0286 0.0476
Brugia malayi Sex muscle abnormal protein 5 0.0016 0.0024 0.004
Onchocerca volvulus 0.0074 0.0256 0.0644
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0016 0.0385
Onchocerca volvulus 0.0016 0.0024 0.006
Onchocerca volvulus 0.0013 0.0013 0.0032
Brugia malayi neuropeptide F receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis sterol regulatory element binding protein 0.0043 0.013 0.013
Echinococcus granulosus hypothetical protein 0.0016 0.0024 0.004
Brugia malayi TAR-binding protein 0.0064 0.0215 0.0358
Echinococcus multilocularis hypothetical protein 0.0074 0.0256 0.0256
Schistosoma mansoni glycogen phosphorylase 0.1007 0.3978 0.6623
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Brugia malayi putative neuropeptide receptor NPR1 0.0013 0.0013 0.0021
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Schistosoma mansoni cpg binding protein 0.003 0.008 0.0132
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0143 0.0531 0.0883
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0054 0.0176 0.0293
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0077 0.0268 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0016 0.0024 0.0024
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0074 0.0256 0.0427
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0016 0.058
Mycobacterium ulcerans hypothetical protein 0.0047 0.0148 0.0873
Schistosoma mansoni protein tyrosine phosphatase 0.0074 0.0256 0.0427
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0013 0.0021
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0148 0.0873
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0162 0.6045
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0016 0.0091
Echinococcus granulosus hypothetical protein 0.0013 0.0013 0.0021
Entamoeba histolytica SH2 domain containing protein 0.0016 0.0024 0.006
Brugia malayi G-protein coupled receptor 0.0013 0.0013 0.0021
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0016 0.0024 0.004
Echinococcus granulosus g protein coupled receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0016 0.0045
Trichomonas vaginalis ran, putative 0.0021 0.0045 0.0113
Loa Loa (eye worm) hypothetical protein 0.0031 0.0085 0.0142
Brugia malayi hypoxia-induced factor 1 0.0295 0.1137 0.1894
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0073 0.0122
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0014 0.0016 0.058
Onchocerca volvulus 0.0074 0.0256 0.0644
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0023 0.0039
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0013 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0013 0.0013
Plasmodium vivax SET domain protein, putative 0.0031 0.0085 0.3179
Onchocerca volvulus 0.0074 0.0256 0.0644
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0074 0.0256 0.0256
Brugia malayi carbohydrate phosphorylase 0.1007 0.3978 0.6623
Plasmodium vivax importin-beta 2, putative 0.0029 0.0075 0.282
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0016 0.0024 0.004
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0148 0.0372
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0016 0.0024 0.0024
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0148 0.0873
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0016 0.0091
Loa Loa (eye worm) hypothetical protein 0.0077 0.0268 0.0446
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Loa Loa (eye worm) MH1 domain-containing protein 0.0018 0.003 0.0051
Onchocerca volvulus 0.0013 0.0013 0.0032
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0024 0.004
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0024 0.004
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni amine GPCR 0.0013 0.0013 0.0021
Schistosoma mansoni hypothetical protein 0.0402 0.1566 0.2607
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Echinococcus granulosus expressed conserved protein 0.0093 0.0333 0.0554
Echinococcus granulosus neuropeptide receptor 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0071 0.0242 0.0608
Echinococcus granulosus tyrosine protein kinase ABL1 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus multilocularis suppressor of cytokine signaling 7 0.0016 0.0024 0.0024
Echinococcus multilocularis tyrosine protein kinase Abl 0.0016 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0013 0.0013
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0085 0.318
Echinococcus multilocularis replication factor c subunit 1 0.001 0.00000034419 0.00000034419
Schistosoma mansoni chromosome transmission fidelity factor 0.001 0.00000034419 0.00000057299
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.1759
Schistosoma mansoni SH2A 0.0016 0.0024 0.004
Echinococcus granulosus neuropeptide receptor A26 0.0013 0.0013 0.0021
Loa Loa (eye worm) TK protein kinase 0.0016 0.0024 0.004
Brugia malayi STAT protein, DNA binding domain containing protein 0.0016 0.0024 0.004
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.1515 0.6007 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0205 0.1206
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0013 0.0013 0.0013
Echinococcus granulosus protein tyrosine phosphatase n9 0.0074 0.0256 0.0427
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0016 0.0024 0.0024
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0059 0.0149
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0074 0.0256 0.0256
Echinococcus granulosus SH2 motif 0.0016 0.0024 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0013 0.0021
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Echinococcus multilocularis N chimaerin 0.0016 0.0024 0.0024
Brugia malayi RhoGAP domain containing protein 0.0016 0.0024 0.004
Echinococcus granulosus Protein patched homolog 1 0.0043 0.013 0.0217
Schistosoma mansoni neuroglian 0.0013 0.0014 0.0023
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.00000034419 0.00000086519
Echinococcus multilocularis glycogen phosphorylase 0.1007 0.3978 0.3978
Onchocerca volvulus 0.0016 0.0024 0.006
Echinococcus granulosus GPCR family 2 0.0016 0.0023 0.0039
Echinococcus multilocularis tensin 0.0016 0.0024 0.0024
Trypanosoma brucei protein tyrosine phosphatase 1 0.0074 0.0256 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni neuropeptide f receptor 76f 0.0013 0.0013 0.0021
Brugia malayi Tensin 0.0016 0.0024 0.004
Trichomonas vaginalis replication factor C large subunit, putative 0.001 0.00000034419 0.00000086519
Trichomonas vaginalis conserved hypothetical protein 0.0043 0.013 0.0328
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0013 0.0014 0.0023
Schistosoma mansoni biogenic amine receptor 0.0013 0.0013 0.0021
Schistosoma mansoni alpha-1 adrenergic receptor 0.0013 0.0013 0.0021
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Onchocerca volvulus 0.0014 0.0016 0.0039
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0016 0.0024 0.0024
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0013 0.0013 0.0013
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0061 0.0205 0.4877
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0014 0.0016 0.0039
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0268 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) projectin 0.0013 0.0014 0.0023
Schistosoma mansoni hypothetical protein 0.0041 0.0124 0.0207
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0016 0.0091
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0059 0.0149
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0025 0.0059 0.0059
Echinococcus granulosus tensin C1 domain containing phosphatase 0.0016 0.0024 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0035 0.0101 0.0168
Onchocerca volvulus 0.0074 0.0256 0.0644
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0054 0.0135
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0093 0.0504
Echinococcus multilocularis sex peptide receptor 0.0013 0.0013 0.0013
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0013 0.0013
Echinococcus granulosus suppressor of cytokine signaling 6 0.0016 0.0024 0.004
Loa Loa (eye worm) hypoxia-induced factor 1 0.0295 0.1137 0.1894
Echinococcus multilocularis transfer RNA-Phe 0.0013 0.0014 0.0014
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0556 0.2179 0.2179
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Echinococcus multilocularis neuropeptide receptor A26 0.0013 0.0013 0.0013
Echinococcus granulosus cpg binding protein 0.003 0.008 0.0132
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0013 0.0021
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0016 0.0045
Schistosoma mansoni tensin 0.0016 0.0024 0.004
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0148 0.5536
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Onchocerca volvulus 0.0013 0.0013 0.0032
Echinococcus multilocularis SH2 motif 0.0016 0.0024 0.0024
Echinococcus multilocularis tyrosine protein kinase Srms 0.0016 0.0024 0.0024
Loa Loa (eye worm) protein-tyrosine phosphatase 0.1515 0.6007 1
Onchocerca volvulus 0.0014 0.0016 0.0039
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0096 0.0161
Echinococcus granulosus tar DNA binding protein 0.0064 0.0215 0.0358
Echinococcus granulosus mothers against decapentaplegic 5 0.0018 0.003 0.0051
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.0159 0.0265
Schistosoma mansoni neuropeptide receptor 0.0013 0.0013 0.0021
Echinococcus granulosus expressed conserved protein 0.0016 0.0024 0.004
Echinococcus multilocularis tyrosine kinase 0.0016 0.0024 0.0024
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.005 0.0159 0.0265
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0013 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Loa Loa (eye worm) SH2 domain-containing protein 0.0016 0.0024 0.004
Onchocerca volvulus 0.0013 0.0013 0.0032
Echinococcus granulosus orexin receptor type 2 0.0013 0.0013 0.0021
Echinococcus granulosus contactin 0.0013 0.0014 0.0023
Loa Loa (eye worm) melatonin receptor type 1A 0.0013 0.0013 0.0021
Echinococcus granulosus g protein coupled receptor 0.0013 0.0013 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis GPCR, family 2 0.0016 0.0023 0.0023
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0431 0.1679 0.2796
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0013 0.0013
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0075 0.282
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0013 0.0021
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0268 0.1577
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0075 0.0075
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0016 0.0385
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0013 0.0021
Schistosoma mansoni myosin xvIII 0.0013 0.0013 0.0021
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0014 0.0023
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0013 0.0021
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0074 0.0256 0.6354
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0093 0.0504
Echinococcus multilocularis serotonin receptor 0.0013 0.0013 0.0013
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0085 0.0085
Schistosoma mansoni hypothetical protein 0.0041 0.0124 0.0207
Brugia malayi hypothetical protein 0.0016 0.0024 0.004
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0077 0.0268 0.0446
Loa Loa (eye worm) protein-tyrosine-phosphatase 0.0074 0.0256 0.0427
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0016 0.0045
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0013 0.0013
Onchocerca volvulus 0.0054 0.0176 0.0443
Echinococcus granulosus nephrin 0.0013 0.0014 0.0023
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi Pre-SET motif family protein 0.0214 0.0815 0.1357
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0016 0.0045
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0013 0.0013 0.0021
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0025 0.0059 0.0099
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Onchocerca volvulus 0.0016 0.0024 0.006
Echinococcus granulosus 7tm_1 domain containing protein 0.0013 0.0013 0.0021
Echinococcus multilocularis Glycosyl transferase, family 35 0.1007 0.3978 0.3978
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0045 0.0075
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0431 0.1679 0.1679
Echinococcus multilocularis growth factor receptor bound protein 2 0.0016 0.0024 0.0024
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0215 0.0358
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0077 0.0268 1
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0074 0.0256 0.0644
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0016 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0016 0.0026
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0013 0.0013 0.0021
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0016 0.0024 0.004
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.1515 0.6007 0.6007
Schistosoma mansoni adapter molecule crk 0.0016 0.0024 0.004
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0025 0.0059 0.0149
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0148 0.0372
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis SH2 motif 0.0016 0.0024 0.0024
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0148 0.0247
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0111 0.0403 1
Echinococcus multilocularis tyrosine protein kinase shark 0.0016 0.0024 0.0024
Giardia lamblia Protein tyrosine phosphatase 0.0074 0.0256 0.0644
Echinococcus granulosus geminin 0.0174 0.0654 0.1089
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0148 0.3419
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0013 0.0013 0.0021
Echinococcus multilocularis aryl hydrocarbon receptor 0.0025 0.0059 0.0059
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0074 0.0256 0.0427
Trypanosoma cruzi tyrosine specific protein phosphatase, putative 0.0111 0.0403 1
Echinococcus granulosus allatostatin A receptor 0.0013 0.0013 0.0021
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Echinococcus granulosus G protein coupled receptor 139 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0111 0.0403 0.0403
Entamoeba histolytica glycogen phosphorylase, putative 0.1007 0.3978 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Echinococcus multilocularis snurportin 1 0.0308 0.1189 0.1189
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0124 0.0457 0.0761
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0013 0.0013 0.0021
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0016 0.0385
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0113
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.001 0.00000034419 0.00000086519
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0075 0.2945
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0013 0.0013 0.0021
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0016 0.0026
Brugia malayi protein unc-22 0.0013 0.0014 0.0023
Onchocerca volvulus Suppressor of cytokine signaling at 36E homolog 0.0016 0.0024 0.006
Echinococcus multilocularis roundabout 2 0.0013 0.0014 0.0014
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Trichomonas vaginalis glycogen phosphorylase, putative 0.1007 0.3978 1
Onchocerca volvulus 0.0031 0.0085 0.0214
Leishmania major protein-tyrosine phosphatase 1-like protein 0.0074 0.0256 0.6208
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Schistosoma mansoni hypothetical protein 0.0016 0.0023 0.0039
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0013 0.0013 0.0032
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Echinococcus multilocularis expressed conserved protein 0.0093 0.0333 0.0333
Onchocerca volvulus 0.0074 0.0256 0.0644
Onchocerca volvulus 0.0025 0.0059 0.0149
Schistosoma mansoni hypothetical protein 0.0016 0.0023 0.0039
Schistosoma mansoni hypothetical protein 0.0016 0.0024 0.004
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0014 0.0016 0.0091
Schistosoma mansoni hypothetical protein 0.0174 0.0654 0.1089
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0016 0.0091
Echinococcus granulosus glycogen phosphorylase 0.1007 0.3978 0.6623
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0023 0.0039
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0085 0.0142
Schistosoma mansoni hypothetical protein 0.0016 0.0024 0.004
Onchocerca volvulus 0.0074 0.0256 0.0644
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0013 0.0021
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0013 0.0021
Schistosoma mansoni histamine h1 receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis protein dispatched 1 0.0049 0.0154 0.0154
Brugia malayi PAS domain containing protein 0.0095 0.0341 0.0567
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0016 0.0026
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0016 0.0024 0.004
Echinococcus multilocularis Niemann Pick C1 protein 0.0142 0.0527 0.0527
Chlamydia trachomatis glycogen phosphorylase 0.1007 0.3978 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Brugia malayi follicle stimulating hormone receptor 0.0013 0.0013 0.0021
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0014 0.0016 0.0091
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0013 0.0021
Schistosoma mansoni smad1 5 8 and 0.0018 0.003 0.0051
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0148 0.0873
Echinococcus granulosus tyrosine kinase 0.0016 0.0024 0.004
Trichomonas vaginalis set domain proteins, putative 0.0244 0.0933 0.2345
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0357 0.0896
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0016 0.0024 0.0024
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0059 0.0149
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0077 0.0268 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0205 0.1206
Echinococcus granulosus tyrosine protein kinase Blk 0.0016 0.0024 0.004
Onchocerca volvulus 0.0074 0.0256 0.0644
Loa Loa (eye worm) hypothetical protein 0.0035 0.0101 0.0168
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0124 0.0457 0.0457
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0014 0.0016 0.0091
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus granulosus dnaJ subfamily B 0.0402 0.1566 0.2607
Schistosoma mansoni GTPase activating protein 0.0016 0.0024 0.004
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0016 0.0605
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0124 0.0457 0.0761
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Onchocerca volvulus Suppressor of cytokine signaling 7 homolog 0.0016 0.0024 0.006
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0074 0.0256 0.0427
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0016 0.0026
Loa Loa (eye worm) hypothetical protein 0.0035 0.0101 0.0168
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Schistosoma mansoni Smad4 0.0018 0.003 0.0051
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0013 0.0014 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Brugia malayi SRC-1 0.0016 0.0024 0.004
Echinococcus granulosus titin 0.0013 0.0014 0.0023
Schistosoma mansoni tyrosine kinase 0.0016 0.0024 0.004
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0013 0.0013
Brugia malayi Probable ClpP-like protease 0.0077 0.0268 0.0446
Echinococcus multilocularis dnaJ subfamily B 0.0402 0.1566 0.1566
Schistosoma mansoni smad1 5 8 and 0.0018 0.003 0.0051
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0531 0.0883
Brugia malayi cytokine inducible SH2-containing protein 5 0.0016 0.0024 0.004
Loa Loa (eye worm) transcription factor SMAD2 0.0258 0.0988 0.1645
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0016 0.0024 0.004
Onchocerca volvulus 0.0016 0.0024 0.006
Echinococcus granulosus peptide allatostatin:somatostatin 0.0013 0.0013 0.0021
Schistosoma mansoni hemicentin 0.0013 0.0014 0.0023
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0016 0.0024 0.004
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Echinococcus granulosus Smad4 0.0018 0.003 0.0051
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0215 0.0358
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0013 0.0013 0.0021
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0014 0.0016 0.0091
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0013 0.0013
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0061 0.0205 0.1165
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0016 0.0024 0.004
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0013 0.0013 0.0021
Schistosoma mansoni ran 0.0021 0.0045 0.0075
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0013 0.0013 0.0021
Brugia malayi Serotonin receptor 0.0013 0.0013 0.0021
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus granulosus TGF beta signal transducer SmadC 0.0018 0.003 0.0051
Echinococcus granulosus roundabout 2 0.0013 0.0014 0.0023
Brugia malayi Importin beta-1 subunit 0.0029 0.0075 0.0126
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0013 0.0021
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0025 0.0059 0.0149
Schistosoma mansoni tyrosine kinase 0.0016 0.0024 0.004
Schistosoma mansoni tensin-related 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0025 0.0059 0.0099
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus granulosus single minded 2 0.0071 0.0242 0.0403
Brugia malayi hypothetical protein 0.0016 0.0024 0.004
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0025 0.0059 0.1468
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0085 0.0142
Schistosoma mansoni protein tyrosine phosphatase 0.0074 0.0256 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0013 0.0013 0.0021
Schistosoma mansoni tyrosine-protein kinase zap-70 0.0016 0.0024 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Brugia malayi MH1 domain containing protein 0.0018 0.003 0.0051
Echinococcus granulosus replication factor c subunit 1 0.001 0.00000034419 0.00000057299
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0016 0.0091
Brugia malayi hypothetical protein 0.0074 0.0256 0.0427
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0013 0.0013 0.0021
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0018 0.003 0.0051
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0016 0.058
Brugia malayi Dopamine receptor protein 1 0.0013 0.0013 0.0021
Schistosoma mansoni hypothetical protein 0.0041 0.0124 0.0207
Schistosoma mansoni amine GPCR 0.0013 0.0013 0.0021
Echinococcus granulosus tyrosine protein kinase Fyn 0.0016 0.0024 0.004
Echinococcus granulosus tumor protein p63 0.037 0.1435 0.239
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0077 0.0268 1
Leishmania major GTP-binding protein, putative 0.0021 0.0045 0.0762
Brugia malayi protein-tyrosine phosphatase Lar-like precursor, putative 0.0111 0.0403 0.0672
Onchocerca volvulus 0.0074 0.0256 0.0644
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0077 0.0268 0.0268
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0025 0.0059 0.1468
Echinococcus granulosus sterol regulatory element binding protein 0.0043 0.013 0.0217
Loa Loa (eye worm) hypothetical protein 0.0034 0.0096 0.0161
Schistosoma mansoni nephrin 0.0013 0.0014 0.0023
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0016 0.0026
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0013 0.0021
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.1685
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0013 0.0013
Schistosoma mansoni suppressor of cytokine signaling 0.0016 0.0024 0.004
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0013 0.0021
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0013 0.0021
Brugia malayi Protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Brugia malayi Serotonin receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Schistosoma mansoni vav2 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0016 0.0024 0.0024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Plasmodium vivax acetyl-CoA synthetase, putative 0.0014 0.0016 0.058
Schistosoma mansoni amine GPCR 0.0013 0.0013 0.0021
Echinococcus granulosus titin 0.0013 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0075
Brugia malayi Pre-SET motif family protein 0.0031 0.0085 0.0142
Echinococcus multilocularis orexin receptor type 2 0.0013 0.0013 0.0013
Loa Loa (eye worm) TYRA-2 protein 0.0013 0.0013 0.0021
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0016 0.0024 0.0024
Mycobacterium ulcerans putative regulatory protein 0.0071 0.0242 0.1425
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0148 0.083
Onchocerca volvulus 0.0074 0.0256 0.0644
Echinococcus granulosus c src tyrosine kinase 0.0016 0.0024 0.004
Onchocerca volvulus 0.0047 0.0148 0.0372
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0016 0.0024 0.006
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0023 0.0039
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0018 0.003 0.003
Echinococcus granulosus sex peptide receptor 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0016 0.0024 0.006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0148 0.083
Echinococcus multilocularis protein patched 0.0043 0.013 0.013
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Echinococcus granulosus neuropeptide s receptor 0.0013 0.0013 0.0021
Trichomonas vaginalis guanylate cyclase, putative 0.0025 0.0059 0.0149
Echinococcus multilocularis Smad4 0.0018 0.003 0.003
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.1118
Echinococcus granulosus signal transduction protein lnk realted 0.0016 0.0024 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0093 0.0504
Loa Loa (eye worm) hypothetical protein 0.0099 0.0357 0.0594
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0013 0.0013 0.0013
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0016 0.0024 0.006
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0024 0.0024
Echinococcus granulosus tyrosine protein kinase shark 0.0016 0.0024 0.004
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Loa Loa (eye worm) glycogen phosphorylase 0.1007 0.3978 0.6623
Echinococcus granulosus SHC transforming protein 3 0.0016 0.0024 0.004
Schistosoma mansoni cell adhesion molecule 0.0013 0.0014 0.0023
Onchocerca volvulus 0.0016 0.0024 0.006
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0013 0.0021
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0101 0.0549
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0074 0.0256 0.0427
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0074 0.0256 0.0256
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0016 0.0024 0.004
Loa Loa (eye worm) MH2 domain-containing protein 0.0018 0.003 0.0051
Brugia malayi RE15519p 0.0013 0.0013 0.0021
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0013 0.0014 0.0035
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) SRC-1 0.0016 0.0024 0.004
Onchocerca volvulus 0.0013 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Brugia malayi hypothetical protein 0.0074 0.0256 0.0427
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0045 0.1685
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0013 0.0013
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0016 0.0024 0.0024
Schistosoma mansoni cell adhesion molecule 0.0013 0.0014 0.0023
Echinococcus granulosus tachykinin peptides receptor 99D 0.0013 0.0013 0.0021
Echinococcus granulosus importin subunit beta 1 0.0029 0.0075 0.0126
Brugia malayi Protein-tyrosine phosphatase 0.0081 0.0286 0.0476
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0013 0.0013
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis neuroglian 0.0013 0.0014 0.0014
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0162 0.0269
Trichomonas vaginalis adenylate cyclase, putative 0.0025 0.0059 0.0149
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0014 0.0016 0.0091
Schistosoma mansoni titin 0.0013 0.0014 0.0023
Schistosoma mansoni opsin-like receptor 0.0013 0.0013 0.0021
Brugia malayi G protein-coupled receptor F59B2.13 0.0013 0.0013 0.0021
Schistosoma mansoni titin 0.0013 0.0014 0.0023
Schistosoma mansoni neuropeptide receptor 0.0013 0.0013 0.0021
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.1515 0.6007 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0268 0.0673
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0024 0.0024
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0013 0.0013 0.0021
Trichomonas vaginalis pten, drome, putative 0.0074 0.0256 0.0644
Brugia malayi Protein kinase domain containing protein 0.0016 0.0024 0.004
Brugia malayi sulfakinin receptor protein 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0111 0.0403 0.1014
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0148 0.0873
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Schistosoma mansoni hypothetical protein 0.0016 0.0023 0.0039
Schistosoma mansoni hypothetical protein 0.0308 0.1189 0.198
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni pcd6 interacting protein-related 0.0074 0.0256 0.0427
Loa Loa (eye worm) STAT protein 0.0016 0.0024 0.004
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0016 0.0039
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Brugia malayi tRNA modification GTPase TrmE family protein 0.0016 0.0024 0.004
Brugia malayi Variant SH3 domain containing protein 0.0016 0.0024 0.004
Onchocerca volvulus 0.0016 0.0024 0.006
Schistosoma mansoni shc transforming protein 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi MH2 domain containing protein 0.0018 0.003 0.0051
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0074 0.0256 0.0427
Echinococcus granulosus neuroglian 0.0013 0.0014 0.0023
Onchocerca volvulus 0.0074 0.0256 0.0644
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0013 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0085 0.0142
Schistosoma mansoni tensin 0.0016 0.0024 0.004
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0178 0.6667
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0013 0.0021
Echinococcus multilocularis dro:myosuppressin receptor 0.0013 0.0013 0.0013
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0074 0.0256 0.0256
Schistosoma mansoni neuropeptide receptor 0.0013 0.0013 0.0021
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0074 0.0256 0.0427
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0085 0.0142
Echinococcus granulosus suppressor of cytokine signaling 7 0.0016 0.0024 0.004
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0061 0.0205 0.0341
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0077 0.0268 1
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis smad 0.0018 0.003 0.003
Echinococcus granulosus serotonin receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0074 0.0256 0.0256
Schistosoma mansoni tyrosine kinase 0.0016 0.0024 0.004
Mycobacterium ulcerans acetyl-CoA synthetase 0.0014 0.0016 0.0091
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0431 0.1679 0.2796
Schistosoma mansoni neuropeptide receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis SH2 domain containing protein 7 0.0016 0.0024 0.0024
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0013 0.0013 0.0021
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0148 0.0873
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0043 0.013 0.0217
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0074 0.0256 0.0256
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0016 0.0024 0.004
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0016 0.0024 0.0024
Schistosoma mansoni glycogen phosphorylase 0.1007 0.3978 0.6623
Leishmania major protein kinase, putative 0.0025 0.0059 0.1126
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0016 0.058
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0531 0.0883
Loa Loa (eye worm) hypothetical protein 0.0035 0.0101 0.0168
Mycobacterium ulcerans aldehyde dehydrogenase 0.0061 0.0205 0.1206
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0124 0.0457 0.0457
Loa Loa (eye worm) SH2 domain-containing protein 0.0016 0.0024 0.004
Loa Loa (eye worm) SH2 domain-containing protein 0.0016 0.0024 0.004
Echinococcus granulosus tyrosine protein kinase Src42A 0.0016 0.0024 0.004
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0054 0.0135
Echinococcus multilocularis suppressor of cytokine signaling 6 0.0016 0.0024 0.0024
Entamoeba histolytica glycogenphosphorylase, putative 0.0435 0.1698 0.4267
Echinococcus granulosus N chimaerin 0.0016 0.0024 0.004
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0025 0.0059 0.1468
Brugia malayi CXXC zinc finger family protein 0.0028 0.0073 0.0122
Brugia malayi Melatonin receptor type 1A 0.0013 0.0013 0.0021
Echinococcus granulosus tyrosine kinase 0.0016 0.0024 0.004
Echinococcus granulosus g protein coupled receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis sortilin receptor 0.0037 0.0107 0.0107
Loa Loa (eye worm) hypothetical protein 0.0052 0.0169 0.0281
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0143 0.0531 0.0883
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis transfer RNA-Lys 0.0071 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0035 0.0101 0.0168
Echinococcus granulosus SH2 motif 0.0016 0.0024 0.004
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0215 0.0358
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0013 0.0021
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0016 0.0026
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0013 0.0013
Schistosoma mansoni amine GPCR 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0074 0.0256 0.0644
Echinococcus granulosus Niemann Pick C1 protein 0.0142 0.0527 0.0877
Onchocerca volvulus 0.0016 0.0024 0.006
Brugia malayi hypothetical protein 0.032 0.1236 0.2058
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0357 0.0357
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0143 0.0531 0.0883
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0101 0.0363 0.0604
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0074 0.0256 0.0427
Loa Loa (eye worm) CAMK protein kinase 0.0013 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus granulosus aryl hydrocarbon receptor 0.0025 0.0059 0.0099
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0016 0.0045
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0077 0.0268 0.1577
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi bHLH-PAS transcription factor 0.0071 0.0242 0.0403
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0016 0.0045
Schistosoma mansoni protein tyrosine phosphatase 0.0081 0.0286 0.0476
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0014 0.0023
Echinococcus multilocularis mothers against decapentaplegic 5 0.0018 0.003 0.003
Giardia lamblia Glycogen phosphorylase 0.1007 0.3978 1
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0431 0.1679 0.2796
Brugia malayi CHE-14 protein 0.0043 0.013 0.0217
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Brugia malayi Protein-tyrosine phosphatase containing protein 0.1515 0.6007 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0013 0.0021
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0016 0.058
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0013 0.0021
Echinococcus multilocularis SH2 domain containing adapter protein F 0.0016 0.0024 0.0024
Onchocerca volvulus 0.0074 0.0256 0.0644
Onchocerca volvulus 0.0028 0.0073 0.0184
Loa Loa (eye worm) hypothetical protein 0.0014 0.0016 0.0026
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Onchocerca volvulus 0.0074 0.0256 0.0644
Echinococcus multilocularis signal transduction protein lnk realted 0.0016 0.0024 0.0024
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Brugia malayi Protein kinase domain containing protein 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0016 0.0045
Entamoeba histolytica glycogen phosphorylase, putative 0.0435 0.1698 0.4267
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi GnHR receptor homolog 0.0013 0.0013 0.0021
Schistosoma mansoni peptidase Clp (S14 family) 0.0077 0.0268 0.0446
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0013 0.0013
Onchocerca volvulus 0.0014 0.0016 0.0039
Brugia malayi G-protein coupled receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0124 0.0457 0.0457
Entamoeba histolytica glycogen phosphorylase, putative 0.1007 0.3978 1
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0074 0.0256 0.0427
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Plasmodium falciparum importin beta, putative 0.0029 0.0075 0.282
Onchocerca volvulus 0.0013 0.0014 0.0035
Onchocerca volvulus 0.0016 0.0024 0.006
Schistosoma mansoni hypothetical protein 0.0013 0.0013 0.0021
Toxoplasma gondii hypothetical protein 0.0027 0.0066 0.2475
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.0159 0.0265
Loa Loa (eye worm) hypothetical protein 0.0029 0.0075 0.0126
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0027 0.0066 0.2475
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0085 0.0142
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0014 0.0016 0.058
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0014 0.0016 0.0091
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0023 0.0039
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0059 0.1468
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) dual specificity protein phosphatase CDC14B 0.0074 0.0256 0.0427
Leishmania major tyrosine specific protein phosphatase, putative 0.0111 0.0403 1
Schistosoma mansoni opsin-like receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0078 0.013
Echinococcus multilocularis 0.0016 0.0024 0.0024
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0016 0.0026
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0013 0.0013 0.0021
Brugia malayi G protein-coupled receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0074 0.0256 0.0644
Schistosoma mansoni tyrosine kinase 0.0016 0.0024 0.004
Schistosoma mansoni aryl hydrocarbon receptor 0.0095 0.0341 0.0567
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0027 0.0066 0.2475
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0016 0.0024 0.004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0044 0.0137 0.0228
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0047 0.0148 0.0247
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Echinococcus multilocularis tumor protein p63 0.037 0.1435 0.1435
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0531 0.0531
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0059 0.0149
Mycobacterium leprae Possible regulatory protein 0.0025 0.0059 0.2213
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0074 0.0256 0.0427
Schistosoma mansoni cpg binding protein 0.003 0.008 0.0132
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0081 0.0286 0.0476
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0013 0.0013 0.0013
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0013 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni suppressor of cytokine signaling 0.0016 0.0024 0.004
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0025 0.0059 0.1126
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0013 0.0013
Echinococcus multilocularis 0.0074 0.0256 0.0256
Echinococcus granulosus neuropeptide FF receptor 2 0.0013 0.0013 0.0021
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0014 0.0016 0.058
Entamoeba histolytica glycogen phosphorylase, putative 0.0435 0.1698 0.4267
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0013 0.0013 0.0013
Schistosoma mansoni smad 0.0018 0.003 0.0051
Brugia malayi hypothetical protein 0.0074 0.0256 0.0427
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0014 0.0023
Schistosoma mansoni biogenic amine receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0023
Schistosoma mansoni hypothetical protein 0.0013 0.0014 0.0023
Brugia malayi larval opioid receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Brugia malayi Protein kinase domain containing protein 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni smad1 5 8 and 0.0018 0.003 0.0051
Onchocerca volvulus 4.1 G protein, putative homolog 0.0074 0.0256 0.0644
Schistosoma mansoni cell adhesion molecule 0.0013 0.0014 0.0023
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0023 0.0023
Brugia malayi MH2 domain containing protein 0.0258 0.0988 0.1645
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0016 0.0091
Entamoeba histolytica Ran family GTPase 0.0021 0.0045 0.0113
Schistosoma mansoni biogenic amine receptor 0.0013 0.0013 0.0021
Leishmania major protein kinase, putative 0.0025 0.0059 0.1126
Loa Loa (eye worm) hypothetical protein 0.0016 0.0023 0.0039
Brugia malayi Dopamine receptor 0.0013 0.0013 0.0021
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0435 0.1698 1
Brugia malayi AKH receptor 0.0013 0.0013 0.0021
Schistosoma mansoni myosin-binding protein-related 0.0013 0.0014 0.0023
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0143 0.0531 0.0531
Mycobacterium ulcerans acyl-CoA synthetase 0.0014 0.0016 0.0091
Onchocerca volvulus 0.0013 0.0013 0.0032
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0111 0.0403 0.0403
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0556 0.2179 0.3628
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0045 0.1118
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0077 0.0268 0.0673
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Trichomonas vaginalis glycogen phosphorylase, putative 0.1007 0.3978 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0148 0.5536
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0148 0.0247
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0013 0.0013
Brugia malayi hypothetical protein 0.0074 0.0256 0.0427
Onchocerca volvulus 0.0074 0.0256 0.0644
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Brugia malayi Smad1 0.0018 0.003 0.0051
Brugia malayi RNA binding protein 0.0064 0.0215 0.0358
Echinococcus granulosus SH2 domain containing adapter protein F 0.0016 0.0024 0.004
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0431 0.1679 0.1679
Echinococcus granulosus smad 0.0018 0.003 0.0051
Brugia malayi Dopamine receptor protein 2 0.0013 0.0013 0.0021
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Schistosoma mansoni tensin-related 0.0016 0.0024 0.004
Entamoeba histolytica hypothetical protein 0.0023 0.0054 0.0135
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0074 0.0256 0.0644
Loa Loa (eye worm) fibronectin type III domain-containing protein 0.0118 0.0433 0.072
Echinococcus multilocularis SHC transforming protein 3 0.0016 0.0024 0.0024
Onchocerca volvulus 0.0013 0.0013 0.0032
Schistosoma mansoni tensin 0.0016 0.0024 0.004
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0016 0.0024 0.006
Brugia malayi Protein-tyrosine phosphatase 1 0.0074 0.0256 0.0427
Brugia malayi Protein kinase domain containing protein 0.0016 0.0024 0.004
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.0159 0.0265
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0074 0.0256 0.0256
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0143 0.0531 0.0883
Loa Loa (eye worm) hypothetical protein 0.0047 0.0148 0.0247
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0016 0.0024 0.0024
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Schistosoma mansoni tyrosine kinase 0.0016 0.0024 0.004
Echinococcus multilocularis geminin 0.0174 0.0654 0.0654
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Echinococcus granulosus alpha 1A adrenergic receptor 0.0013 0.0013 0.0021
Echinococcus granulosus g-protein coupled receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Onchocerca volvulus Neuropeptide F receptor homolog 0.0013 0.0013 0.0032
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0118 0.0433 0.0433
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0357 0.0594
Schistosoma mansoni hypothetical protein 0.0174 0.0654 0.1089
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0074 0.0256 0.0427
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0308 0.1189 0.198
Leishmania major importin beta-1 subunit, putative 0.0023 0.0054 0.0985
Echinococcus granulosus glycogen phosphorylase 0.1007 0.3978 0.6623
Schistosoma mansoni growth factor receptor-bound protein 0.0016 0.0024 0.004
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0025 0.0059 0.1468
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0431 0.1679 0.2796
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0013 0.0021
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0204 0.034
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi putative neuropeptide receptor 0.0013 0.0013 0.0021
Onchocerca volvulus 0.0074 0.0256 0.0644
Onchocerca volvulus Glycogen phosphorylase homolog 0.1007 0.3978 1
Schistosoma mansoni hypothetical protein 0.0016 0.0023 0.0039
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0074 0.0256 0.0256
Schistosoma mansoni signal transduction protein lnk-related 0.0016 0.0024 0.004
Echinococcus granulosus phosphatidylinositol 3 kinase regulatory subunit 0.0016 0.0024 0.004
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.0815 0.1357
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0215 0.0215
Echinococcus multilocularis G protein coupled receptor 139 0.0013 0.0013 0.0013
Onchocerca volvulus 0.0013 0.0013 0.0032
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0074 0.0256 0.0427
Echinococcus multilocularis roundabout 2 0.0013 0.0014 0.0014
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0074 0.0256 0.0427
Echinococcus granulosus tyrosine protein kinase Src42A 0.0016 0.0024 0.004
Echinococcus multilocularis phosphatidylinositol 3 kinase regulatory subunit 0.0016 0.0024 0.0024
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0118 0.0433 0.072
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0014 0.0023
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0025 0.0059 0.0149
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0162 0.0162
Echinococcus multilocularis NCK adaptor protein 0.0016 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi RNA, U transporter 1 0.0082 0.0288 0.0479
Echinococcus multilocularis titin 0.0013 0.0014 0.0014
Echinococcus multilocularis G-protein coupled receptor, putative 0.0013 0.0013 0.0013
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0045 0.0075
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0045 0.1685
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0013 0.0021
Echinococcus granulosus tyrosine protein kinase Src64B 0.0016 0.0024 0.004
Echinococcus granulosus tensin 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0043 0.013 0.0217
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Brugia malayi hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni hypothetical protein 0.0034 0.0096 0.0161
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Schistosoma mansoni single-minded 0.0095 0.0341 0.0567
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0074 0.0256 0.0256
Schistosoma mansoni nck2/grb4 0.0016 0.0024 0.004
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0013 0.0013
Onchocerca volvulus 0.0013 0.0013 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0016 0.0024 0.0024
Onchocerca volvulus 0.0074 0.0256 0.0644
Brugia malayi MH2 domain containing protein 0.0018 0.003 0.0051
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0013 0.0013
Onchocerca volvulus 0.0013 0.0013 0.0032
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0074 0.0256 0.0427
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Schistosoma mansoni opsin-like receptor 0.0013 0.0013 0.0021
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0435 0.1698 1
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0162 0.0911
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Loa Loa (eye worm) protein tyrosine phosphatase 0.0074 0.0256 0.0427
Onchocerca volvulus 0.0013 0.0014 0.0035
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0111 0.0403 0.0403
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0016 0.0024 0.004
Loa Loa (eye worm) MH2 domain-containing protein 0.0258 0.0988 0.1645
Echinococcus multilocularis serotonin receptor 0.0013 0.0013 0.0013
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0013 0.0013 0.0013
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0023
Loa Loa (eye worm) oxidoreductase 0.0014 0.0016 0.0026
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0215 0.0358
Onchocerca volvulus 0.0013 0.0013 0.0032
Echinococcus multilocularis allatostatin A receptor 0.0013 0.0013 0.0013
Schistosoma mansoni patched 1 0.0043 0.013 0.0217
Brugia malayi Protein kinase domain containing protein 0.0016 0.0024 0.004
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0013 0.0021
Entamoeba histolytica protein tyrosine phosphatase, putative 0.0074 0.0256 0.0644
Schistosoma mansoni aldehyde dehydrogenase 0.0061 0.0205 0.0341
Loa Loa (eye worm) hypothetical protein 0.0074 0.0256 0.0427
Schistosoma mansoni cpg binding protein 0.0028 0.0073 0.0122
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0016 0.0039
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis neuropeptide s receptor 0.0013 0.0013 0.0013
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0013 0.0013 0.0021
Echinococcus multilocularis g-protein coupled receptor 0.0013 0.0013 0.0013
Schistosoma mansoni adenoreceptor 0.0013 0.0013 0.0021
Schistosoma mansoni importin beta-1 0.0029 0.0075 0.0126
Echinococcus granulosus neuropeptide receptor 0.0013 0.0013 0.0021
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0013 0.0021
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0118 0.0433 0.0433
Entamoeba histolytica protein kinase, putative 0.0016 0.0024 0.006
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0124 0.0457 0.0761
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0013 0.0021
Schistosoma mansoni growth hormone secretagogue receptor 0.0013 0.0013 0.0021
Echinococcus granulosus 7TM GPCR rhodopsin 0.0013 0.0013 0.0021
Echinococcus multilocularis tyrosine protein kinase Blk 0.0016 0.0024 0.0024
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0074 0.0256 0.0427
Onchocerca volvulus 0.0013 0.0013 0.0032
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0013 0.0021
Brugia malayi protein-tyrosine kinase 0.0016 0.0024 0.004
Echinococcus multilocularis cpg binding protein 0.003 0.008 0.008
Brugia malayi hypothetical protein 0.0074 0.0256 0.0427
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0025 0.0059 0.0099
Brugia malayi SH2 domain containing protein 0.0016 0.0024 0.004
Onchocerca volvulus 0.0013 0.0013 0.0032
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0013 0.0013 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0016 0.0024 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0013 0.0021
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0025 0.0059 0.0149
Echinococcus granulosus dro:myosuppressin receptor 0.0013 0.0013 0.0021
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0074 0.0256 0.0427
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0148 0.3419
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0118 0.0433 0.072
Onchocerca volvulus 0.0244 0.0933 0.2345

Activities

Activity type Activity value Assay description Source Reference
APTT (functional) = 47.7 s Anticoagulant activity was determined in Ortho-activated thrombofax (APTT) assay at a dose 9.4 microM in human dead plasma ChEMBL. 8176707
APTT (functional) = 87.3 s Anticoagulant activity was determined in Ortho-activated thrombofax (APTT) assay at a dose 31 microM in human dead plasma ChEMBL. 8176707
APTT (functional) > 120 s Anticoagulant activity was determined in Ortho-activated thrombofax (APTT) assay at a dose 16 microM in pig plasma ChEMBL. 8176707
K obs / 1 (binding) = 1790 M-1 s-1 Inhibition of porcine factor IXa at 8.3-82 uM ChEMBL. 8176707
K obs / 1 (binding) = 3140 M-1 s-1 Inhibition of human coagulation factor VII at 7.2-44 uM ChEMBL. 8176707
K obs / 1 (binding) = 4740 M-1 s-1 Inhibition of human factor Xa (inhibitor concentration were 3.6-44 uM) ChEMBL. 8176707
K obs / 1 (binding) = 22400 M-1 s-1 Inhibition of human thrombin (inhibitor concentration 1.2-54 microM) ChEMBL. 8176707
K obs / 1 (binding) = 25000 M-1 s-1 Inhibition of bovine thrombin (inhibitor concentration 1.2-54 uM) ChEMBL. 8176707
K obs / 1 (binding) = 50000 M-1 s-1 Inhibition of human coagulation factor XII (inhibitor concentration were 3.6-4.9 uM) ChEMBL. 8176707
K obs / 1 (binding) = 104000 M-1 s-1 Compound was evaluated for inhibition of enzyme human coagulation factor XI (inhibitor concentration were 0.7-0.8 uM) ChEMBL. 8176707
PT (binding) = 28.5 s Anticoagulant activity in PT assay at a dose 16 microM ChEMBL. 8176707
PT (binding) = 58.3 s Anticoagulant activity in PT assay at a dose 32 microM ChEMBL. 8176707
T1/2 (ADMET) = 108 min Hydrolysis half life (t1/2) ChEMBL. 8176707

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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