Detailed information for compound 332387

Basic information

Technical information
  • TDR Targets ID: 332387
  • Name: (2R)-2-[4-(2-methylpropyl)phenyl]propanamide
  • MW: 205.296 | Formula: C13H19NO
  • H donors: 1 H acceptors: 1 LogP: 2.9 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(Cc1ccc(cc1)[C@H](C(=O)N)C)C
  • InChi: 1S/C13H19NO/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H2,14,15)/t10-/m1/s1
  • InChiKey: REUQKCDCQVNKLW-SNVBAGLBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R)-2-(4-isobutylphenyl)propanamide
  • (2R)-2-(4-isobutylphenyl)propionamide
  • ZINC00112491

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Melatonin receptor type 1A 0.0278 0.1076 0.1076
Echinococcus granulosus nuclear factor of activated T cells 5 0.0073 0.0244 0.025
Echinococcus multilocularis cathepsin L 0.0073 0.0247 0.0253
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0014 0.0006 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0247 0.3385
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0073 0.0247 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0189 0.0716 0.4981
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0073 0.0247 0.3446
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.0716
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) hypothetical protein 0.0048 0.0145 0.0145
Echinococcus multilocularis cysteine protease 0.0189 0.0716 0.0734
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Schistosoma mansoni hypothetical protein 0.0407 0.1598 0.1639
Brugia malayi Cathepsin L-like precursor 0.0189 0.0716 0.0716
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0011
Brugia malayi Histone deacetylase family protein 0.0041 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0033 0.0083 0.0083
Giardia lamblia Encystation-specific protease 0.0073 0.0247 0.1681
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0278 0.1076 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1023 0.4097 0.4201
Trypanosoma cruzi UNC119 0.0027 0.0058 0.0142
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0051 0.0154 0.0158
Leishmania major cathepsin L-like protease 0.0189 0.0716 0.4981
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0031 0.0075 0.6166
Toxoplasma gondii cathepsin CPC1 0.0073 0.0247 0.1716
Plasmodium falciparum histone deacetylase, putative 0.0041 0.0115 0.1612
Trypanosoma cruzi cysteine peptidase, putative 0.0189 0.0716 0.1748
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Echinococcus multilocularis g-protein coupled receptor 0.0278 0.1076 0.1104
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0007 0.0061
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0142 0.0145
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0104 0.1367
Trichomonas vaginalis retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase, putative 0.0133 0.0489 0.3402
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.0115
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0247 0.0247
Echinococcus granulosus thioredoxin glutathione reductase 0.009 0.0315 0.0323
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0007 0.0007
Echinococcus granulosus lysosomal alpha glucosidase 0.0172 0.0646 0.0662
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0189 0.0716 1
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0086
Trypanosoma brucei glucosidase, putative 0.0038 0.0104 0.0721
Onchocerca volvulus 0.0278 0.1076 1
Brugia malayi putative neuropeptide receptor 0.0278 0.1076 0.1076
Echinococcus multilocularis sex peptide receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0104 0.0104
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0006 0.0043
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0073 0.0247 0.0253
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0054 0.0168 0.1171
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0031 0.0075 0.0523
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0247 0.1716
Plasmodium falciparum phosphodiesterase gamma, putative 0.0014 0.0006 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0278 0.1076 0.1104
Plasmodium vivax unspecified product 0.0073 0.0247 0.3446
Echinococcus granulosus cathepsin l1 0.0189 0.0716 0.0734
Brugia malayi Cathepsin L-like precursor 0.0189 0.0716 0.0716
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0247 0.1716
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0091 0.0316 0.0772
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0451 1
Schistosoma mansoni cpg binding protein 0.003 0.0071 0.0073
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0014 0.0006 0.0043
Trypanosoma cruzi histone deacetylase, putative 0.0041 0.0115 0.0282
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0104 0.0721
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0367 0.1438 1
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0073 0.0247 0.1681
Entamoeba histolytica cysteine proteinase 1, putative 0.0073 0.0247 0.3385
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0051 0.0154 0.1073
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0086
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0073 0.0247 0.0253
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0007
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0195 0.02
Echinococcus granulosus histone deacetylase 0.0041 0.0115 0.0118
Echinococcus granulosus Ankyrin 0.0014 0.0007 0.0007
Onchocerca volvulus 0.0073 0.0245 0.2274
Onchocerca volvulus 0.0278 0.1076 1
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Brugia malayi cathepsin L-like precursor 0.0189 0.0716 0.0716
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0037 0.0097 0.0403
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0011
Echinococcus granulosus neuropeptide Y receptor 0.0278 0.1076 0.1104
Leishmania major cathepsin L-like protease 0.0189 0.0716 0.4981
Loa Loa (eye worm) hypothetical protein 0.0073 0.0247 0.0247
Giardia lamblia Cathepsin L precursor 0.0073 0.0247 0.1681
Leishmania major cathepsin L-like protease 0.0189 0.0716 0.4981
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0073 0.0245 0.1217
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0046
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0245 0.1703
Onchocerca volvulus Cathepsin F homolog 0.0189 0.0716 0.6654
Entamoeba histolytica hypothetical protein 0.0073 0.0247 0.3385
Loa Loa (eye worm) latrophilin receptor protein 2 0.0015 0.0011 0.0011
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0228 0.0872 0.4672
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Echinococcus multilocularis G-protein coupled receptor, putative 0.0278 0.1076 0.1104
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0104 0.0104
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0073 0.0247 0.3385
Echinococcus multilocularis histone deacetylase 0.0041 0.0115 0.0118
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Trichomonas vaginalis mercuric reductase, putative 0.0031 0.0075 0.0523
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0189 0.0716 1
Schistosoma mansoni amine GPCR 0.0278 0.1076 0.1104
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0054 0.0168 0.1171
Trypanosoma cruzi major cysteine proteinase, putative 0.0073 0.0247 0.0602
Onchocerca volvulus 0.0278 0.1076 1
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0073 0.0247 0.1716
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0036 0.0094 0.0654
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0014 0.0006 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0046
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0014 0.0006 0.0006
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Trypanosoma brucei cysteine peptidase C (CPC) 0.0367 0.1438 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0278 0.1076 0.1104
Trichomonas vaginalis conserved hypothetical protein 0.0091 0.0316 0.2201
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0014 0.0006 0.0006
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0073 0.0247 0.3446
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0247 0.1681
Onchocerca volvulus Neuropeptide F receptor homolog 0.0278 0.1076 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0104 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Schistosoma mansoni inositol monophosphatase 0.0039 0.0107 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0043
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0014 0.0006 0.0006
Echinococcus granulosus beta LACTamase domain containing family member 0.0073 0.0245 0.0251
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0024 0.0124
Entamoeba histolytica cysteine proteinase, putative 0.0189 0.0716 1
Onchocerca volvulus 0.0278 0.1076 1
Plasmodium falciparum serine repeat antigen 9 0.0073 0.0247 0.3446
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0051 0.0154 0.0154
Mycobacterium ulcerans hypothetical protein 0.0073 0.0245 0.5425
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Leishmania major glycosyl hydrolase-like protein 0.0014 0.0007 0.0046
Onchocerca volvulus 0.0278 0.1076 1
Schistosoma mansoni opsin-like receptor 0.0278 0.1076 0.1104
Schistosoma mansoni hypothetical protein 0.0033 0.0083 0.0085
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0278 0.1076 0.1104
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0024 0.0167
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0205 0.0779 0.4162
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0023 0.0043 0.0044
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0521 0.206 0.206
Onchocerca volvulus 0.0036 0.0094 0.0874
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0107 0.0261
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trypanosoma cruzi cysteine peptidase, putative 0.0189 0.0716 0.1748
Trichomonas vaginalis penicillin-binding protein, putative 0.0073 0.0245 0.1703
Giardia lamblia Cathepsin B precursor 0.0073 0.0247 0.1681
Echinococcus multilocularis cathepsin L cysteine protease 0.0189 0.0716 0.0734
Echinococcus multilocularis serotonin receptor 0.2418 0.9752 1
Brugia malayi Cathepsin L-like precursor 0.0189 0.0716 0.0716
Echinococcus granulosus histone deacetylase 6 0.0041 0.0115 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Brugia malayi G protein-coupled receptor F59B2.13 0.0278 0.1076 0.1076
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0189 0.0716 0.0716
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Mycobacterium tuberculosis Probable esterase LipL 0.0073 0.0245 0.1217
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0015 0.0011 0.0011
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0075 0.0183
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0278 0.1076 0.1104
Brugia malayi Calcitonin receptor-like protein seb-1 0.0048 0.0145 0.0145
Onchocerca volvulus 0.0189 0.0716 0.6654
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0086
Giardia lamblia Cathepsin L precursor 0.0073 0.0247 0.1681
Brugia malayi Protein kinase domain containing protein 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0037 0.0097 0.0097
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Echinococcus multilocularis orexin receptor type 2 0.0278 0.1076 0.1104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Brugia malayi Papain family cysteine protease containing protein 0.0189 0.0716 0.0716
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0142 0.0145
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Giardia lamblia Cathepsin L precursor 0.0073 0.0247 0.1681
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Brugia malayi Cathepsin L-like cysteine proteinase 0.0189 0.0716 0.0716
Giardia lamblia Hypothetical protein 0.0027 0.0058 0.0362
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0073 0.0247 0.3446
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0107 0.0744
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Trypanosoma cruzi UNC119 0.0027 0.0058 0.0142
Toxoplasma gondii histone deacetylase HDAC1 0.0041 0.0115 0.0803
Echinococcus multilocularis dro:myosuppressin receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis serotonin receptor 0.2418 0.9752 1
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0097 0.0086
Echinococcus granulosus g protein coupled receptor 0.0278 0.1076 0.1104
Brugia malayi G protein-coupled receptor 0.0278 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.0716
Echinococcus granulosus tm gpcr rhodopsin 0.0278 0.1076 0.1104
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0245 0.1703
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Schistosoma mansoni amine GPCR 0.0278 0.1076 0.1104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0247 0.1681
Brugia malayi Uncoordinated protein 44 0.0014 0.0007 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Loa Loa (eye worm) hypothetical protein 0.0073 0.0245 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0014 0.0006 0.0006
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0247 0.3385
Trypanosoma brucei UNC119 0.0027 0.0058 0.0404
Brugia malayi fibroinase precursor 0.0073 0.0247 0.0247
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Echinococcus granulosus cpg binding protein 0.003 0.0071 0.0073
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0073 0.0247 0.3385
Onchocerca volvulus 0.0278 0.1076 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.0245 0.0245
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0278 0.1076 0.1104
Toxoplasma gondii hypothetical protein 0.0037 0.0097 0.0675
Brugia malayi ORL1-like opioid receptor 0.0278 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Giardia lamblia Cathepsin L-like protease 0.0073 0.0247 0.1681
Leishmania major histone deacetylase, putative 0.0041 0.0115 0.0803
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0278 0.1076 0.1104
Trypanosoma cruzi aminopeptidase, putative 0.0036 0.0094 0.0229
Plasmodium vivax thioredoxin reductase, putative 0.009 0.0313 0.437
Trypanosoma cruzi cysteine protease, putative 0.0073 0.0247 0.0602
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0043
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0014 0.0006 0.0043
Loa Loa (eye worm) neuropeptide F receptor 0.0278 0.1076 0.1076
Schistosoma mansoni cathepsin C 0.0073 0.0247 0.0253
Echinococcus granulosus cathepsin l1 0.0189 0.0716 0.0734
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0014 0.0006 0.0006
Plasmodium falciparum serine repeat antigen 5 0.0073 0.0247 0.3446
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Toxoplasma gondii exonuclease III APE 0.0018 0.0024 0.0167
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0036 0.0094 0.0096
Mycobacterium ulcerans beta-lactamase 0.0073 0.0245 0.5425
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.3125 0.3204
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0247 0.3385
Echinococcus granulosus neuropeptide s receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0073 0.0247 0.0247
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0036 0.0094 0.0096
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0014 0.0006 0.0006
Echinococcus granulosus allatostatin A receptor 0.0278 0.1076 0.1104
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0075 0.0183
Plasmodium falciparum serine repeat antigen 4 0.0073 0.0247 0.3446
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0247 0.1716
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0007 0.0007
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0031 0.0075 0.1049
Schistosoma mansoni cathepsin F (C01 family) 0.0189 0.0716 0.0734
Mycobacterium tuberculosis Probable dehydrogenase 0.0205 0.0779 0.4162
Schistosoma mansoni biogenic amine (5HT) receptor 0.2418 0.9752 1
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0247 0.0247
Schistosoma mansoni hypothetical protein 0.0014 0.0007 0.0007
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0073 0.0247 0.1681
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0091 0.0316 0.2201
Loa Loa (eye worm) hypothetical protein 0.0073 0.0245 0.0245
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0247 0.0253
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Echinococcus granulosus neuropeptide FF receptor 2 0.0278 0.1076 0.1104
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0024 0.0024
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0007 0.0046
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Echinococcus multilocularis neuropeptide receptor A26 0.0278 0.1076 0.1104
Echinococcus granulosus neuropeptide receptor 0.0278 0.1076 0.1104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0278 0.1076 0.1076
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0014 0.0006 0.0006
Echinococcus multilocularis dnaJ subfamily B 0.0407 0.1598 0.1639
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0015 0.0011 0.0011
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0006 0.0015
Loa Loa (eye worm) histone deacetylase 7A 0.0041 0.0115 0.0115
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Trypanosoma cruzi Aminopeptidase M1, putative 0.0036 0.0094 0.0229
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Echinococcus granulosus histone deacetylase 6 0.0041 0.0115 0.0118
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0247 0.0253
Plasmodium falciparum serine repeat antigen 1 0.0073 0.0247 0.3446
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0091 0.0316 0.2201
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0073 0.0247 0.3446
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0247 0.1716
Echinococcus multilocularis histone deacetylase 6 0.0041 0.0115 0.0118
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0228 0.0872 0.4672
Plasmodium falciparum glutathione reductase 0.0031 0.0075 0.1049
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0046
Giardia lamblia Cathepsin L precursor 0.0073 0.0247 0.1681
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0031 0.0075 0.1665
Toxoplasma gondii thioredoxin reductase 0.009 0.0313 0.2177
Onchocerca volvulus 0.0278 0.1076 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0247 0.0253
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0247 0.1716
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0104 0.0721
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0014 0.0006 0.0006
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Loa Loa (eye worm) hypothetical protein 0.0073 0.0247 0.0247
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0046
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0247 0.1716
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0107 0.0744
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Loa Loa (eye worm) hypothetical protein 0.0041 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.2418 0.9752 0.9752
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0247 0.1716
Trichomonas vaginalis rotamase, putative 0.0032 0.008 0.0555
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.0716
Echinococcus multilocularis Ankyrin 0.0014 0.0007 0.0007
Trypanosoma brucei histone deacetylase, putative 0.0041 0.0115 0.0803
Brugia malayi cathepsin Z-like cysteine proteinase 0.0073 0.0247 0.0247
Trypanosoma cruzi cysteine peptidase, putative 0.0189 0.0716 0.1748
Brugia malayi neuropeptide F receptor 0.0278 0.1076 0.1076
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0031 0.0075 0.0523
Leishmania major hypothetical protein, conserved 0.0027 0.0058 0.0404
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Onchocerca volvulus 0.0073 0.0245 0.2274
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0091 0.0316 0.0325
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0014 0.0006 0.0006
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0014 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0014 0.0006 0.0006
Trypanosoma cruzi major cysteine proteinase, putative 0.0073 0.0247 0.0602
Entamoeba histolytica cysteine proteinase, putative 0.0189 0.0716 1
Loa Loa (eye worm) cysteine protease 0.0189 0.0716 0.0716
Loa Loa (eye worm) G-protein coupled receptor 0.0278 0.1076 0.1076
Schistosoma mansoni hypothetical protein 0.0278 0.1076 0.1104
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0278 0.1076 0.1104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Onchocerca volvulus 0.0073 0.0245 0.2274
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0051 0.0154 0.0154
Toxoplasma gondii NADPH-glutathione reductase 0.0031 0.0075 0.0523
Onchocerca volvulus Cathepsin L homolog 0.0189 0.0716 0.6654
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0014 0.0006 0.0006
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Echinococcus granulosus neuropeptide receptor 0.0278 0.1076 0.1104
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0031 0.0075 0.0523
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0247 0.1716
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0031 0.0075 0.1665
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0075 0.0183
Schistosoma mansoni ap endonuclease 0.0018 0.0024 0.0025
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0189 0.0716 0.0734
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0014 0.0006 0.0006
Giardia lamblia Cathepsin B precursor 0.0367 0.1438 1
Echinococcus granulosus sex peptide receptor 0.0278 0.1076 0.1104
Brugia malayi CXXC zinc finger family protein 0.0029 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Brugia malayi Inositol-1 0.0039 0.0107 0.0107
Leishmania major cathepsin L-like protease 0.0189 0.0716 0.4981
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0104 0.0721
Schistosoma mansoni alpha-1 adrenergic receptor 0.0278 0.1076 0.1104
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0031 0.0075 0.1665
Giardia lamblia Cathepsin L-like protease 0.0073 0.0247 0.1681
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0023 0.0043 0.0105
Leishmania major cathepsin L-like protease 0.0189 0.0716 0.4981
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0247 0.1716
Onchocerca volvulus 0.0036 0.0094 0.0874
Trypanosoma cruzi cruzipain precursor, putative 0.0189 0.0716 0.1748
Loa Loa (eye worm) hypothetical protein 0.0073 0.0247 0.0247
Schistosoma mansoni neuropeptide f receptor 76f 0.0278 0.1076 0.1104
Brugia malayi Dopamine receptor 0.0278 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Brugia malayi follicle stimulating hormone receptor 0.0521 0.206 0.206
Schistosoma mansoni opsin-like receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Onchocerca volvulus 0.0278 0.1076 1
Trichomonas vaginalis esterase, putative 0.0073 0.0245 0.1703
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0278 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.2418 0.9752 0.9752
Echinococcus granulosus cysteine protease 0.0073 0.0247 0.0253
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0073 0.0247 0.3446
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0051 0.0154 0.0158
Mycobacterium tuberculosis Conserved protein 0.0073 0.0245 0.1217
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0451 1
Mycobacterium ulcerans esterase/lipase LipP 0.0073 0.0245 0.5425
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0075 0.0183
Schistosoma mansoni amine GPCR 0.0278 0.1076 0.1104
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0073 0.0245 0.1217
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Onchocerca volvulus 0.0278 0.1076 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0278 0.1076 0.1104
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0189 0.0716 0.0716
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0039 0.0107 1
Loa Loa (eye worm) hypothetical protein 0.1023 0.4097 0.4097
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.0077 0.0534
Brugia malayi beta-lactamase family protein 0.0073 0.0245 0.0245
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0104 0.0106
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0043
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0036 0.0094 0.0096
Schistosoma mansoni opsin-like receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0032 0.008 0.008
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0142 0.0145
Onchocerca volvulus 0.0189 0.0716 0.6654
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0051 0.0154 0.0158
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Loa Loa (eye worm) PDE1B protein 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0073 0.0247 0.0247
Echinococcus granulosus inositol monophosphatase 1 0.0039 0.0107 0.011
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0278 0.1076 0.1104
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.1023 0.4097 0.4201
Schistosoma mansoni biogenic amine receptor 0.0278 0.1076 0.1104
Toxoplasma gondii GAF domain-containing protein 0.0037 0.0097 0.0675
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.009 0.0313 0.1593
Onchocerca volvulus 0.0029 0.0065 0.0602
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Brugia malayi Cathepsin L-like precursor 0.0189 0.0716 0.0716
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0278 0.1076 0.1104
Echinococcus multilocularis GPCR, family 2 0.0015 0.0011 0.0011
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0073 0.0247 0.1716
Plasmodium vivax vivapain-1 0.0073 0.0247 0.3446
Trypanosoma brucei histone deacetylase 4 0.0041 0.0115 0.0803
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0107 0.0744
Echinococcus multilocularis neuropeptide Y receptor 0.0278 0.1076 0.1104
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0024 0.0245
Echinococcus multilocularis cathepsin b 0.1023 0.4097 0.4201
Brugia malayi Histone deacetylase family protein 0.0041 0.0115 0.0115
Echinococcus granulosus peptide allatostatin:somatostatin 0.0278 0.1076 0.1104
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0278 0.1076 0.1104
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0073 0.0247 0.3446
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Mycobacterium tuberculosis Conserved protein 0.0073 0.0245 0.1217
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1023 0.4097 0.4201
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.0077 0.0989
Schistosoma mansoni rotamase 0.0032 0.008 0.0082
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0031 0.0075 0.0523
Schistosoma mansoni biogenic amine receptor 0.0278 0.1076 0.1104
Leishmania major cathepsin L-like protease 0.0189 0.0716 0.4981
Plasmodium vivax histone deacetylase 2, putative 0.0041 0.0115 0.1612
Brugia malayi beta-lactamase family protein 0.0073 0.0245 0.0245
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0073 0.0247 0.0247
Echinococcus granulosus somatostatin receptor 0.0278 0.1076 0.1104
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Giardia lamblia Cathepsin L precursor 0.0073 0.0247 0.1681
Schistosoma mansoni histone deacetylase 4 5 0.0041 0.0115 0.0118
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0073 0.0245 0.0245
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0031 0.0075 0.1049
Trypanosoma cruzi cysteine proteinase, putative 0.0073 0.0247 0.0602
Echinococcus granulosus death domain containing protein 0.0014 0.0007 0.0007
Schistosoma mansoni adenoreceptor 0.0278 0.1076 0.1104
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0278 0.1076 0.1076
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Trypanosoma brucei trypanothione reductase 0.009 0.0313 0.2177
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0037 0.0097 0.2152
Treponema pallidum NADH oxidase 0.0031 0.0075 1
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Mycobacterium tuberculosis Probable lipase LipD 0.0073 0.0245 0.1217
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0073 0.0247 0.0602
Loa Loa (eye worm) hypothetical protein 0.0051 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Leishmania major hypothetical protein, conserved 0.0014 0.0006 0.0043
Trypanosoma brucei Aminopeptidase M1, putative 0.0036 0.0094 0.0654
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Entamoeba histolytica cysteine proteinase, putative 0.0073 0.0247 0.3385
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0014 0.0006 0.0006
Plasmodium falciparum glutathione reductase 0.009 0.0313 0.437
Echinococcus granulosus histone deacetylase 7 0.0041 0.0115 0.0118
Brugia malayi G-protein coupled receptor 0.0278 0.1076 0.1076
Plasmodium vivax serine-repeat antigen (SERA) 0.0073 0.0247 0.3446
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0007 0.0016
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0168 0.1171
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0024 0.0025
Brugia malayi Death domain containing protein 0.0014 0.0007 0.0007
Echinococcus multilocularis beta LACTamase domain containing family member 0.0073 0.0245 0.0251
Schistosoma mansoni neuropeptide F-like receptor 0.0278 0.1076 0.1104
Echinococcus granulosus cathepsin L cysteine protease 0.0073 0.0247 0.0253
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0278 0.1076 0.1104
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0205 0.0779 0.8814
Mycobacterium ulcerans aldehyde dehydrogenase 0.0124 0.0451 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis neuropeptide s receptor 0.0278 0.1076 0.1104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0014 0.0006 0.0006
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0023 0.0042 0.0042
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0031 0.0075 0.5
Echinococcus multilocularis cysteine protease 0.0189 0.0716 0.0734
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0073 0.0247 0.3446
Toxoplasma gondii cathepsin CPC2 0.0073 0.0247 0.1716
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0091 0.0316 0.0772
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Echinococcus granulosus neuropeptide Y receptor 0.0278 0.1076 0.1104
Brugia malayi glutathione reductase 0.009 0.0313 0.0313
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0104 0.0721
Onchocerca volvulus 0.0278 0.1076 1
Echinococcus granulosus cathepsin L 0.0073 0.0247 0.0253
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0228 0.0872 1
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0014 0.0006 0.0006
Echinococcus granulosus histone deacetylase 6 0.0041 0.0115 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Schistosoma mansoni cpg binding protein 0.0029 0.0065 0.0066
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0091 0.0316 0.2201
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0036 0.0094 0.0229
Toxoplasma gondii hypothetical protein 0.0037 0.0097 0.0675
Giardia lamblia Cysteine protease 0.0073 0.0247 0.1681
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0073 0.0247 0.3446
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Brugia malayi Thioredoxin reductase 0.009 0.0313 0.0313
Brugia malayi Peptidase family M1 containing protein 0.0036 0.0094 0.0094
Trichomonas vaginalis rotamase, putative 0.0032 0.0077 0.0534
Schistosoma mansoni cathepsin F (C01 family) 0.0189 0.0716 0.0734
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0024 0.0531
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0124 0.0451 0.2355
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0104 0.0721
Entamoeba histolytica cysteine proteinase, putative 0.0189 0.0716 1
Brugia malayi hypothetical protein 0.0036 0.0094 0.0094
Schistosoma mansoni biogenic amine (5HT) receptor 0.0278 0.1076 0.1104
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Echinococcus granulosus g protein coupled receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0278 0.1076 0.1104
Schistosoma mansoni myosin xvIII 0.0278 0.1076 0.1104
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0278 0.1076 0.1104
Echinococcus granulosus serotonin receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0007
Schistosoma mansoni histone deacetylase 4 5 0.0041 0.0115 0.0118
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Trypanosoma cruzi trypanothione reductase, putative 0.009 0.0313 0.0764
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0142 0.0145
Onchocerca volvulus 0.0278 0.1076 1
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0091 0.0316 0.0325
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Schistosoma mansoni alpha-glucosidase 0.0148 0.0549 0.0563
Plasmodium falciparum serine repeat antigen 3 0.0073 0.0247 0.3446
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0073 0.0247 0.3446
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0006 0.0015
Echinococcus multilocularis expressed protein 0.0032 0.008 0.0082
Echinococcus granulosus alpha 1A adrenergic receptor 0.0278 0.1076 0.1104
Echinococcus granulosus neuropeptides capa receptor 0.0278 0.1076 0.1104
Leishmania major cAMP-specific phosphodiesterase, putative 0.0014 0.0006 0.0043
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0014 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0091 0.0316 0.2201
Loa Loa (eye worm) hypothetical protein 0.0073 0.0245 0.0245
Leishmania major cathepsin L-like protease 0.0189 0.0716 0.4981
Onchocerca volvulus 0.0278 0.1076 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0278 0.1076 0.1104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0247 0.1716
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0024 0.0058
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0048 0.0142 0.0145
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0104 0.0721
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0031 0.0075 0.6166
Trypanosoma brucei hypothetical protein, conserved 0.0014 0.0006 0.0043
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0031 0.0075 0.0282
Trypanosoma cruzi trypanothione reductase, putative 0.0031 0.0075 0.0183
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0097 0.1356
Echinococcus granulosus g protein coupled receptor 0.0278 0.1076 0.1104
Plasmodium falciparum thioredoxin reductase 0.0031 0.0075 0.1049
Giardia lamblia Cathepsin B precursor 0.0073 0.0247 0.1681
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0073 0.0247 0.3446
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0023 0.0042 0.0042
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0051 0.0154 0.1073
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0007 0.0007
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0245 0.0597
Brugia malayi beta-lactamase 0.0073 0.0245 0.0245
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Mycobacterium ulcerans lipase LipD 0.0073 0.0245 0.5425
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0075 0.0183
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.0077 0.0534
Echinococcus multilocularis neuropeptides capa receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Loa Loa (eye worm) glutathione reductase 0.009 0.0313 0.0313
Plasmodium vivax serine-repeat antigen (SERA) 0.0073 0.0247 0.3446
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0024 0.0167
Trichomonas vaginalis inositol monophosphatase, putative 0.0039 0.0107 0.0744
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0245 0.1703
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0247 0.0253
Plasmodium vivax hypothetical protein, conserved 0.0073 0.0245 0.3418
Echinococcus multilocularis cathepsin b 0.1023 0.4097 0.4201
Entamoeba histolytica cysteine protease, putative 0.0189 0.0716 1
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0091 0.0316 0.0772
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0031 0.0075 0.0183
Loa Loa (eye worm) thioredoxin reductase 0.009 0.0313 0.0313
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0039 0.0107 0.0744
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0189 0.0716 0.4981
Schistosoma mansoni neuropeptide receptor 0.0278 0.1076 0.1104
Plasmodium vivax unspecified product 0.0073 0.0247 0.3446
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0039 0.0107 0.0261
Entamoeba histolytica cysteine proteinase 2 0.0073 0.0247 0.3385
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Toxoplasma gondii cathepsin CPL 0.0189 0.0716 0.4981
Echinococcus multilocularis cathepsin L 0.0073 0.0247 0.0253
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0031 0.0075 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0259 0.1804
Mycobacterium tuberculosis Probable lipase LipE 0.0073 0.0245 0.1217
Leishmania major cysteine peptidase A (CPA) 0.0189 0.0716 0.4981
Echinococcus granulosus G protein coupled receptor 139 0.0278 0.1076 0.1104
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0014 0.0006 0.0015
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0048 0.0142 0.0145
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Mycobacterium tuberculosis Conserved protein 0.0073 0.0245 0.1217
Loa Loa (eye worm) hypothetical protein 0.0073 0.0245 0.0245
Plasmodium falciparum serine repeat antigen 6 0.0073 0.0247 0.3446
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0073 0.0247 0.0247
Echinococcus granulosus neuropeptides capa receptor 0.0278 0.1076 0.1104
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0278 0.1076 0.1104
Echinococcus multilocularis inositol monophosphatase 1 0.0039 0.0107 0.011
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0259 0.1804
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0039 0.0107 0.237
Brugia malayi neuropeptide F receptor 0.0278 0.1076 0.1076
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0073 0.0247 0.3446
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0073 0.0247 0.3446
Brugia malayi Cathepsin L-like precursor 0.0189 0.0716 0.0716
Schistosoma mansoni neuropeptide F-like receptor 0.0278 0.1076 0.1104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Trypanosoma brucei Aminopeptidase M1, putative 0.0036 0.0094 0.0654
Onchocerca volvulus 0.0189 0.0716 0.6654
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0014 0.0006 0.0006
Loa Loa (eye worm) inositol-1 0.0039 0.0107 0.0107
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0097 0.2152
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0124 0.0451 0.0463
Trypanosoma cruzi histone deacetylase, putative 0.0041 0.0115 0.0282
Echinococcus granulosus biogenic amine 5HT receptor 0.2418 0.9752 1
Echinococcus multilocularis aminopeptidase N 0.0036 0.0094 0.0096
Echinococcus granulosus aminopeptidase N 0.0036 0.0094 0.0096
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0014 0.0007 0.0046
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0278 0.1076 0.1076
Echinococcus granulosus orexin receptor type 2 0.0278 0.1076 0.1104
Giardia lamblia Cathepsin B precursor 0.0073 0.0247 0.1681
Echinococcus multilocularis somatostatin receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Loa Loa (eye worm) hypothetical protein 0.0073 0.0245 0.0245
Plasmodium vivax phosphodiesterase gamma, putative 0.0014 0.0006 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0073 0.0247 0.1716
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0031 0.0075 0.0523
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0036 0.0094 0.0654
Echinococcus multilocularis thioredoxin glutathione reductase 0.009 0.0315 0.0323
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0031 0.0075 0.1049
Brugia malayi Peptidase family M1 containing protein 0.0036 0.0094 0.0094
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0278 0.1076 0.1104
Brugia malayi cathepsin Z-like cysteine proteinase 0.0073 0.0247 0.0247
Schistosoma mansoni histone deacetylase hda2 0.0041 0.0115 0.0118
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Echinococcus granulosus tm gpcr rhodopsin 0.0278 0.1076 0.1104
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0073 0.0247 0.0253
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0205 0.0779 0.4162
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0278 0.1076 0.1104
Plasmodium falciparum serine repeat antigen 7 0.0073 0.0247 0.3446
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0011
Brugia malayi cathepsin F-like cysteine proteinase 0.0073 0.0247 0.0247
Plasmodium falciparum cysteine proteinase falcipain 3 0.0189 0.0716 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0014 0.0006 0.0086
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0031 0.0075 0.0077
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.0716
Loa Loa (eye worm) melatonin receptor type 1A 0.0278 0.1076 0.1076
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0278 0.1076 0.1104
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0032 0.008 0.008
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Loa Loa (eye worm) hypothetical protein 0.0023 0.0043 0.0043
Plasmodium vivax vivapain-3 0.0073 0.0247 0.3446
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0278 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0023 0.0043 0.0043
Echinococcus multilocularis neuropeptide Y receptor 0.0278 0.1076 0.1104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Mycobacterium tuberculosis Probable reductase 0.0205 0.0779 0.4162
Giardia lamblia Hypothetical protein 0.0073 0.0247 0.1681
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0073 0.0247 0.0253
Giardia lamblia Cysteine protease 0.0073 0.0247 0.1681
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0245 0.0251
Loa Loa (eye worm) hypothetical protein 0.0133 0.0489 0.0489
Toxoplasma gondii cathepsin B 0.0367 0.1438 1
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0247 0.1716
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0048 0.0142 0.0145
Brugia malayi AKH receptor 0.0278 0.1076 0.1076
Trypanosoma brucei hypothetical protein, conserved 0.0073 0.0245 0.1703
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0278 0.1076 0.1104
Echinococcus multilocularis g protein coupled receptor 0.0278 0.1076 0.1104
Echinococcus granulosus cathepsin l cysteine peptidase 0.0189 0.0716 0.0734
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0043
Echinococcus granulosus neuropeptide receptor A26 0.0278 0.1076 0.1104
Giardia lamblia Cysteine protease 0.0073 0.0247 0.1681
Schistosoma mansoni alpha-glucosidase 0.0148 0.0549 0.0563
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.1023 0.4097 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0247 0.1716
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0073 0.0247 0.1716
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0036 0.0094 0.0654
Brugia malayi Cathepsin L-like precursor 0.0189 0.0716 0.0716
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0031 0.0075 0.0075
Onchocerca volvulus Cathepsin L homolog 0.0073 0.0247 0.2293
Echinococcus granulosus 7tm_1 domain containing protein 0.0278 0.1076 0.1104
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Echinococcus multilocularis fmrfamide receptor 0.0278 0.1076 0.1104
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0451 0.0463
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0054 0.0168 0.0411
Onchocerca volvulus 0.0278 0.1076 1
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0014 0.0006 0.0015
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0006 0.0015
Mycobacterium ulcerans aminopeptidase N PepN 0.0036 0.0094 0.2084
Schistosoma mansoni hypothetical protein 0.0278 0.1076 0.1104
Giardia lamblia Cathepsin B precursor 0.0367 0.1438 1
Echinococcus granulosus cathepsin b 0.1023 0.4097 0.4201
Toxoplasma gondii hypothetical protein 0.0077 0.0259 0.1804
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Schistosoma mansoni biogenic amine receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis fmrfamide receptor 0.0278 0.1076 0.1104
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0014 0.0006 0.0043
Schistosoma mansoni netrin receptor unc5 0.0014 0.0007 0.0007
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0051 0.0154 0.1073
Echinococcus multilocularis neuropeptide receptor 0.0278 0.1076 0.1104
Echinococcus granulosus expressed protein 0.0032 0.008 0.0082
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0073 0.0245 0.5425
Schistosoma mansoni neuropeptide receptor 0.0278 0.1076 0.1104
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0007 0.0007
Brugia malayi hypothetical protein 0.0278 0.1076 0.1076
Toxoplasma gondii preprocathepsin c precursor, putative 0.0073 0.0247 0.1716
Onchocerca volvulus 0.0189 0.0716 0.6654
Plasmodium falciparum GAF domain-related protein, putative 0.0037 0.0097 0.1356
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0065 0.0065
Brugia malayi putative neuropeptide receptor NPR1 0.0278 0.1076 0.1076
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0043
Onchocerca volvulus 0.0278 0.1076 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0189 0.0716 0.4981
Onchocerca volvulus 0.0278 0.1076 1
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0073 0.0247 0.0253
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0039 0.0107 0.0744
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0367 0.1438 0.3509
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0278 0.1076 0.1104
Schistosoma mansoni ap endonuclease 0.0018 0.0024 0.0025
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0024 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0097 0.0675
Trichomonas vaginalis conserved hypothetical protein 0.0073 0.0247 0.1716
Echinococcus granulosus biogenic amine 5HT receptor 0.0278 0.1076 0.1104
Trypanosoma cruzi cysteine peptidase, putative 0.0073 0.0247 0.0602
Onchocerca volvulus 0.0073 0.0247 0.2293
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Echinococcus multilocularis g protein coupled receptor 0.0278 0.1076 0.1104
Onchocerca volvulus 0.0189 0.0716 0.6654
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Leishmania major histone deacetylase, putative 0.0041 0.0115 0.0803
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Plasmodium vivax vivapain-2 0.0189 0.0716 1
Loa Loa (eye worm) hypothetical protein 0.2479 1 1
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0031 0.0075 0.0077
Echinococcus multilocularis allatostatin A receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0023 0.0043 0.0044
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0031 0.0075 0.0523
Mycobacterium tuberculosis Probable hydrolase 0.0073 0.0245 0.1217
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0031 0.0075 0.0077
Trichomonas vaginalis D-aminoacylase, putative 0.0073 0.0245 0.1703
Loa Loa (eye worm) TYRA-2 protein 0.0278 0.1076 0.1076
Brugia malayi hypothetical protein 0.0027 0.0058 0.0058
Schistosoma mansoni retinal rod rhodopsin-sensitive cgmp 3'5'-cyclic phosphodiesterase 0.0133 0.0489 0.0501
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0073 0.0245 0.0251
Trypanosoma brucei histone deacetylase 3 0.0041 0.0115 0.0803
Schistosoma mansoni hypothetical protein 0.0278 0.1076 0.1104
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.0077 0.0534
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0048 0.0145 0.0145
Loa Loa (eye worm) hypothetical protein 0.0073 0.0247 0.0247
Loa Loa (eye worm) ctsf protein 0.0189 0.0716 0.0716
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0104 0.0721
Loa Loa (eye worm) hypothetical protein 0.0023 0.0043 0.0043
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0077 0.0187
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0014 0.0007 0.0061
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0073 0.0245 0.0245
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Onchocerca volvulus 0.0189 0.0716 0.6654
Onchocerca volvulus 0.0189 0.0716 0.6654
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0048 0.0142 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0172 0.0646 0.0646
Schistosoma mansoni neuropeptide receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis histone deacetylase 7 0.0041 0.0115 0.0118
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.1023 0.4097 0.4201
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0043
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0189 0.0716 0.0734
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0007 0.0007
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0006 0.0015
Trypanosoma brucei glycosyl hydrolase-like protein 0.0014 0.0007 0.0046
Plasmodium falciparum phosphodiesterase delta, putative 0.0014 0.0006 0.0086
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0007 0.0007
Schistosoma mansoni histamine h1 receptor 0.0278 0.1076 0.1104
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0104 0.0721
Loa Loa (eye worm) histone deacetylase 0.0041 0.0115 0.0115
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Loa Loa (eye worm) aminopeptidase N 0.0036 0.0094 0.0094
Leishmania major hypothetical protein, conserved 0.0073 0.0245 0.1703
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0024 0.0335
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0014 0.0006 0.0006
Mycobacterium leprae conserved hypothetical protein 0.0073 0.0245 0.1976
Loa Loa (eye worm) neuropeptide F receptor 0.0278 0.1076 0.1076
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0278 0.1076 0.1076
Echinococcus granulosus tm gpcr rhodopsin 0.0278 0.1076 0.1104
Brugia malayi Cathepsin L-like precursor 0.0189 0.0716 0.0716
Schistosoma mansoni neuropeptide receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) fibroinase 0.0189 0.0716 0.0716
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0124 0.0451 0.0463
Schistosoma mansoni amine GPCR 0.0278 0.1076 0.1104
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0124 0.0451 0.3139
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0278 0.1076 0.1104
Brugia malayi Glycosyl hydrolases family 31 protein 0.0172 0.0646 0.0646
Echinococcus granulosus GPCR family 2 0.0015 0.0011 0.0011
Plasmodium vivax vivapain-2 0.0189 0.0716 1
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0247 0.0247
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0014 0.0006 0.0043
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0247 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0247 0.1716
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0646 0.0662
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0104 0.0721
Brugia malayi Serotonin receptor 0.0278 0.1076 0.1076
Trypanosoma cruzi histone deacetylase, putative 0.0041 0.0115 0.0282
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0031 0.0075 0.0523
Giardia lamblia Cathepsin B precursor 0.0367 0.1438 1
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0104 0.0106
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0014 0.0006 0.0043
Plasmodium falciparum thioredoxin reductase 0.009 0.0313 0.437
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0024 0.0167
Giardia lamblia Cysteine protease 0.0073 0.0247 0.1681
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0259 0.1804
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0278 0.1076 0.1104
Brugia malayi sulfakinin receptor protein 0.0278 0.1076 0.1076
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0073 0.0247 0.1716
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0036 0.0094 0.0654
Plasmodium vivax histone deacetylase, putative 0.0041 0.0115 0.1612
Giardia lamblia Cathepsin B precursor 0.0073 0.0247 0.1681
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0014 0.0006 0.0015
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0024 0.0058
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0036 0.0094 0.0654
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0278 0.1076 0.1104
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0104 0.1367
Brugia malayi latrophilin 2 splice variant baaae 0.0033 0.0083 0.0083
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Echinococcus multilocularis lysosomal alpha glucosidase 0.0172 0.0646 0.0662
Schistosoma mansoni cpg binding protein 0.003 0.0071 0.0073
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0367 0.1438 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0048 0.0145 0.0145
Leishmania major trypanothione reductase 0.009 0.0313 0.2177
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Plasmodium vivax glutathione reductase, putative 0.009 0.0313 0.437
Brugia malayi G-protein coupled receptor 0.0278 0.1076 0.1076
Schistosoma mansoni cathepsin B (C01 family) 0.0073 0.0247 0.0253
Onchocerca volvulus 0.0278 0.1076 1
Toxoplasma gondii ABC1 family protein 0.0073 0.0245 0.1703
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0104 0.0721
Echinococcus granulosus hypothetical protein 0.0278 0.1076 0.1104
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0278 0.1076 0.1104
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Schistosoma mansoni alpha glucosidase 0.0038 0.0104 0.0106
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0073 0.0245 0.1217
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Trypanosoma cruzi cysteine peptidase, putative 0.0189 0.0716 0.1748
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0035 0.009 0.0366
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0189 0.0716 0.1748
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0278 0.1076 0.1104
Echinococcus granulosus tachykinin peptides receptor 99D 0.0278 0.1076 0.1104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Echinococcus granulosus dnaJ subfamily B 0.0407 0.1598 0.1639
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0015 0.0011 0.0011
Echinococcus granulosus g-protein coupled receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0278 0.1076 0.1076
Echinococcus granulosus cathepsin b 0.1023 0.4097 0.4201
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0104 0.0253
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Brugia malayi RE15519p 0.0278 0.1076 0.1076
Brugia malayi Tachykinin-like peptides receptor 99D 0.0278 0.1076 0.1076
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0278 0.1076 0.1076
Schistosoma mansoni hypothetical protein 0.0278 0.1076 0.1104
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0006
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0278 0.1076 0.1104
Brugia malayi hypothetical protein 0.0133 0.0489 0.0489
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0247 0.0247
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0091 0.0316 0.2201
Brugia malayi cathepsin B-like cysteine proteinase 0.1023 0.4097 0.4097
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0006 0.0015
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0205 0.0779 0.4162
Loa Loa (eye worm) cathepsin B 0.0367 0.1438 0.1438
Loa Loa (eye worm) G-protein coupled receptor 0.0278 0.1076 0.1076
Giardia lamblia NADH oxidase lateral transfer candidate 0.0031 0.0075 0.0482
Brugia malayi GnHR receptor homolog 0.0278 0.1076 0.1076
Brugia malayi Papain family cysteine protease containing protein 0.0073 0.0247 0.0247
Echinococcus granulosus rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0031 0.0075 0.0523
Loa Loa (eye worm) hypothetical protein 0.0027 0.0058 0.0058
Echinococcus multilocularis histone deacetylase 6 0.0041 0.0115 0.0118
Giardia lamblia Cathepsin B precursor 0.0073 0.0247 0.1681
Trypanosoma cruzi hypothetical protein, conserved 0.0073 0.0245 0.0597
Echinococcus granulosus fmrfamide receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0073 0.0244 0.025
Echinococcus multilocularis G protein coupled receptor 139 0.0278 0.1076 0.1104
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Brugia malayi Cathepsin L-like precursor 0.0189 0.0716 0.0716
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0073 0.0247 0.1716
Brugia malayi Serotonin receptor 0.0278 0.1076 0.1076
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0278 0.1076 0.1104
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0247 0.1716
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0006 0.0043
Echinococcus multilocularis histone deacetylase 6 0.0041 0.0115 0.0118
Brugia malayi cathepsin L precursor 0.0073 0.0247 0.0247
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0014 0.0006 0.0006
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0091 0.0316 0.2201
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0024 0.0167
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0007 0.0007
Echinococcus granulosus cathepsin L cysteine proteinase 0.0189 0.0716 0.0734
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0073 0.0247 0.0253
Echinococcus granulosus cathepsin L 0.0073 0.0247 0.0253
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0073 0.0247 0.1716
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0073 0.0247 0.0253
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0104 0.0721
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0278 0.1076 0.1104
Onchocerca volvulus 0.0099 0.0352 0.327
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0024 0.0024
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0073 0.0247 0.1716
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0073 0.0247 0.3446
Brugia malayi Dopamine receptor protein 2 0.0278 0.1076 0.1076
Schistosoma mansoni cathepsin S (C01 family) 0.0073 0.0247 0.0253
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0007
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0086
Mycobacterium tuberculosis Probable oxidoreductase 0.0228 0.0872 0.4672
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0278 0.1076 0.1104
Trypanosoma cruzi hypothetical protein, conserved 0.0014 0.0006 0.0015
Giardia lamblia Hypothetical protein 0.0073 0.0247 0.1681
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Plasmodium falciparum serine repeat antigen 8 0.0073 0.0247 0.3446
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0039 0.0107 0.1414
Schistosoma mansoni hypothetical protein 0.0015 0.0011 0.0011
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0466 0.1839 1
Brugia malayi cathepsin L-like cysteine proteinase 0.0073 0.0247 0.0247
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Echinococcus multilocularis neuropeptide receptor 0.0278 0.1076 0.1104
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0205 0.0779 0.4162
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0048 0.0142 0.0142
Onchocerca volvulus Cathepsin L homolog 0.0189 0.0716 0.6654
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Echinococcus multilocularis cpg binding protein 0.003 0.0071 0.0073
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0015 0.0011 0.0011
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0014 0.0006 0.0006
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0015 0.0011 0.0011
Plasmodium falciparum serine repeat antigen 2 0.0073 0.0247 0.3446
Schistosoma mansoni cathepsin F (C01 family) 0.0189 0.0716 0.0734
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0014 0.0006 0.0006
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0278 0.1076 0.1104
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0014 0.0007 0.0016
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0006 0.0043
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0278 0.1076 0.1076
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Plasmodium falciparum histone deacetylase 2 0.0041 0.0115 0.1612
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0015 0.0011 0.0011
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0007 0.0007
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0014 0.0006 0.0043
Onchocerca volvulus 0.0278 0.1076 1
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0189 0.0716 0.4981
Echinococcus multilocularis rhodopsin orphan GPCR 0.0278 0.1076 0.1104
Schistosoma mansoni inositol monophosphatase 0.0039 0.0107 0.011
Leishmania major hypothetical protein, conserved 0.0014 0.0006 0.0043
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0036 0.0094 0.0096
Echinococcus multilocularis g protein coupled receptor 0.0278 0.1076 0.1104
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0278 0.1076 0.1104
Echinococcus multilocularis neuropeptides capa receptor 0.0278 0.1076 0.1104
Loa Loa (eye worm) beta-lactamase 0.0073 0.0245 0.0245
Mycobacterium leprae Probable lipase LipE 0.0073 0.0245 0.1976
Trichomonas vaginalis alpha-glucosidase, putative 0.0014 0.0007 0.0046
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Brugia malayi Latrophilin receptor protein 2 0.0015 0.0011 0.0011
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0189 0.0716 0.4981
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0014 0.0006 0.0086
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0031 0.0075 0.1049
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0367 0.1438 0.1474
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0014 0.0006 0.0043
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0014 0.0006 0.0043
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0091 0.0316 0.0325
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Leishmania major cathepsin L-like protease 0.0189 0.0716 0.4981
Brugia malayi larval opioid receptor 0.0278 0.1076 0.1076
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0278 0.1076 0.1104
Giardia lamblia Cathepsin L precursor 0.0073 0.0247 0.1681
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0014 0.0006 0.0006
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0024 0.0335
Trichomonas vaginalis glutathione reductase, putative 0.0031 0.0075 0.0523
Schistosoma mansoni aldehyde dehydrogenase 0.0124 0.0451 0.0463
Echinococcus multilocularis cathepsin L cysteine protease 0.0189 0.0716 0.0734
Plasmodium falciparum cysteine proteinase falcipain 1 0.0073 0.0247 0.3446
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0014 0.0006 0.0006
Toxoplasma gondii aldehyde dehydrogenase 0.0124 0.0451 0.3139
Echinococcus granulosus dro:myosuppressin receptor 0.0278 0.1076 0.1104
Trypanosoma cruzi cysteine proteinase, putative 0.0073 0.0247 0.0602
Trichomonas vaginalis maltase-glucoamylase, putative 0.0014 0.0007 0.0046
Onchocerca volvulus 0.0189 0.0716 0.6654
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.008 0.0555
Entamoeba histolytica cysteine protease, putative 0.0073 0.0247 0.3385
Schistosoma mansoni growth hormone secretagogue receptor 0.0278 0.1076 0.1104
Schistosoma mansoni amine GPCR 0.0278 0.1076 0.1104
Mycobacterium ulcerans putative regulatory protein 0.0037 0.0097 0.2152
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0031 0.0075 0.0183
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0014 0.0006 0.0043
Loa Loa (eye worm) hypothetical protein 0.0278 0.1076 0.1076
Loa Loa (eye worm) hypothetical protein 0.0073 0.0247 0.0247
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0031 0.0075 0.0183
Entamoeba histolytica aminopeptidase, putative 0.0036 0.0094 0.1232
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0037 0.0097 0.0403
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.0077 0.0187

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) = 12 % Inhibition of lipopolysaccharide-induced PGE-2 production at 10e-5 M ChEMBL. 15974585
Inhibition (functional) = 12 % Inhibition of lipopolysaccharide-induced PGE-2 production at 10e-5 M ChEMBL. 15974585
Inhibition (functional) = 67 % Inhibition of CXCL8-induced chemotaxis of human polymorphonuclear cells at 10e-8 M ChEMBL. 15974585
Inhibition (functional) = 67 % Inhibition of CXCL8-induced chemotaxis of human polymorphonuclear cells at 10e-8 M ChEMBL. 15974585

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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