Detailed information for compound 36264

Basic information

Technical information
  • TDR Targets ID: 36264
  • Name: phenyl N-[[(2S)-2-acetamido-3-phenylpropanoyl ]amino]carbamate
  • MW: 341.361 | Formula: C18H19N3O4
  • H donors: 3 H acceptors: 3 LogP: 2.35 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Oc1ccccc1)NNC(=O)[C@H](Cc1ccccc1)NC(=O)C
  • InChi: 1S/C18H19N3O4/c1-13(22)19-16(12-14-8-4-2-5-9-14)17(23)20-21-18(24)25-15-10-6-3-7-11-15/h2-11,16H,12H2,1H3,(H,19,22)(H,20,23)(H,21,24)/t16-/m0/s1
  • InChiKey: DUDLMBMQLMPFBN-INIZCTEOSA-N  


Substructure search Similarity search

Network

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Synonyms

  • phenyl N-[[(2S)-2-acetamido-3-phenyl-propanoyl]amino]carbamate
  • N-[[(2S)-2-acetamido-1-oxo-3-phenylpropyl]amino]carbamic acid phenyl ester
  • N-[[(2S)-2-acetamido-3-phenyl-propanoyl]amino]carbamic acid phenyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax casein kinase 1, putative 0.0063 0.0182 0.1511
Brugia malayi Protein kinase domain containing protein 0.0212 0.1529 0.1647
Leishmania major casein kinase II, putative 0.0097 0.0486 0.2076
Leishmania major casein kinase, putative 0.0063 0.0182 0.0711
Echinococcus multilocularis casein kinase I delta 0.0063 0.0182 0.0199
Echinococcus multilocularis serine:threonine protein kinase 38 0.0146 0.0935 0.1114
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0486 0.2086
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0046 0.0024 0.001
Schistosoma mansoni protein kinase 0.0233 0.1723 0.2959
Echinococcus multilocularis death associated protein kinase 1 0.0952 0.8243 1
Loa Loa (eye worm) hypothetical protein 0.007 0.0241 0.0246
Schistosoma mansoni kinase 0.0312 0.2441 0.4205
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0046 0.0023 0.0004
Echinococcus multilocularis nervana 2 0.0141 0.089 0.1059
Toxoplasma gondii CMGC kinase, CK2 family 0.0097 0.0486 0.2107
Loa Loa (eye worm) hypothetical protein 0.0061 0.0161 0.0159
Plasmodium vivax glycogen synthase kinase 3, putative 0.0129 0.0782 0.7235
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0066 0.0205 0.0226
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0054 0.0096 0.032
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0698 0.5938 0.6439
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0262 0.1984 0.239
Trypanosoma cruzi casein kinase, putative 0.0063 0.0182 0.081
Echinococcus granulosus serine:threonine protein kinase 3 0.0276 0.2111 0.2096
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0146 0.0935 0.1
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0069 0.0235 0.0216
Trypanosoma brucei protein kinase, putative 0.0078 0.0316 0.1299
Brugia malayi Protein kinase domain containing protein 0.0203 0.1447 0.1557
Loa Loa (eye worm) AGC/PKC/ALPHA protein kinase 0.0067 0.0214 0.0217
Trypanosoma cruzi aurora B kinase, putative 0.0149 0.0956 0.4251
Loa Loa (eye worm) AGC/AKT protein kinase 0.0294 0.2274 0.2456
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Echinococcus granulosus casein kinase I delta 0.0063 0.0182 0.0164
Echinococcus granulosus serine:threonine kinase SAD 1 0.0046 0.0024 0.0005
Echinococcus granulosus nervana 2 0.0141 0.089 0.0873
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0024 0.0016
Loa Loa (eye worm) hypothetical protein 0.0089 0.0417 0.0437
Echinococcus granulosus casein kinase ii subunit alpha 0.0097 0.0486 0.0468
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0316 0.1335
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0046 0.0024 0.0002
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0163 0.109 0.1303
Brugia malayi Variant SH3 domain containing protein 0.0061 0.0161 0.0159
Loa Loa (eye worm) hypothetical protein 0.0089 0.0417 0.0437
Brugia malayi Protein kinase domain containing protein 0.0199 0.1417 0.1524
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0046 0.0024 0.0006
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0066 0.0205 0.0911
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0163 0.109 0.1303
Entamoeba histolytica serine/threonine-protein kinase 3, putative 0.0079 0.0326 0.1342
Loa Loa (eye worm) AUR protein kinase 0.0149 0.0956 0.1024
Giardia lamblia Kinase, CMGC CDK 0.0118 0.068 0.2946
Brugia malayi p70 ribosomal S6 kinase beta 0.0288 0.2217 0.2394
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0316 0.1335
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0063 0.0182 0.0182
Brugia malayi SH2 domain containing protein 0.0069 0.0235 0.0239
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0079 0.0326 0.1448
Onchocerca volvulus 0.005 0.0058 0.0113
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0122 0.0715 0.0762
Leishmania major protein kinase A catalytic subunit isoform 2 0.0066 0.0205 0.0813
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Echinococcus granulosus neuroglian 0.0106 0.0565 0.0547
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0118 0.068 0.0723
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0782 0.337
Loa Loa (eye worm) hypothetical protein 0.0069 0.0235 0.0239
Schistosoma mansoni serine/threonine protein kinase 0.0433 0.3535 0.6099
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0123 0.0719 0.3122
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0069 0.0235 0.0937
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0078 0.0316 0.1333
Entamoeba histolytica protein kinase, putative 0.0102 0.0536 0.2278
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0066 0.0205 0.0226
Onchocerca volvulus 0.0334 0.2637 0.5132
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0046 0.0024 0.0006
Onchocerca volvulus 0.0129 0.0782 0.1522
Brugia malayi SRC-1 0.0163 0.109 0.1169
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0284 0.2188 0.2637
Echinococcus granulosus protein kinase c iota type 0.028 0.2149 0.2134
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0262 0.1058
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0129 0.0782 0.0834
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.068 0.2915
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.0148 0.095 0.1132
Leishmania major protein kinase, putative 0.0055 0.0111 0.039
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0164 0.1098 0.4879
Brugia malayi ephrin receptor 1 precursor 0.007 0.0241 0.0246
Brugia malayi Fibronectin type III domain containing protein 0.0089 0.0417 0.0437
Brugia malayi cell division control protein 2 homolog 0.0118 0.068 0.0723
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0183 0.1265 0.1249
Loa Loa (eye worm) hypothetical protein 0.0126 0.0751 0.08
Brugia malayi hypothetical protein 0.0089 0.0417 0.0437
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0498 0.4126 0.4994
Echinococcus multilocularis serine:threonine protein kinase 0.0113 0.0631 0.0745
Echinococcus granulosus calcium:calmodulin dependent protein kinase I 0.0063 0.0182 0.0164
Brugia malayi Protein kinase domain containing protein 0.0069 0.0235 0.0239
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0183 0.1265 0.1515
Echinococcus multilocularis serine:threonine protein kinase Chk2 0.0063 0.0183 0.0199
Schistosoma mansoni tyrosine kinase 0.0443 0.3628 0.6261
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Echinococcus multilocularis casein kinase i 0.0063 0.0182 0.0199
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Echinococcus granulosus N chimaerin 0.0073 0.0268 0.025
Loa Loa (eye worm) hypothetical protein 0.0045 0.0019 0.0004
Echinococcus granulosus serine:threonine protein kinase Chk2 0.0063 0.0183 0.0164
Brugia malayi Protein kinase domain containing protein 0.0122 0.0715 0.0762
Echinococcus multilocularis Immunoglobulin 0.0086 0.0392 0.0453
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Loa Loa (eye worm) hypothetical protein 0.0159 0.1046 0.1122
Echinococcus granulosus casein kinase I alpha 0.0063 0.0182 0.0164
Echinococcus granulosus calcium activated potassium channel 0.009 0.0424 0.0406
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0205 0.033
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Brugia malayi Hr1 repeat family protein 0.0146 0.0935 0.1
Schistosoma mansoni protein kinase 0.0046 0.0024 0.0017
Schistosoma mansoni hypothetical protein 0.007 0.0241 0.0393
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0081 0.034 0.0391
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0046 0.0024 0.0002
Toxoplasma gondii aurora kinase 0.0149 0.0956 0.4252
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0066 0.0205 0.0187
Echinococcus multilocularis rho associated protein kinase 0.0354 0.2819 0.3405
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0486 0.2086
Onchocerca volvulus 0.0132 0.0809 0.1574
Trichomonas vaginalis STE family protein kinase 0.0081 0.034 0.1439
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0073 0.0268 0.025
Loa Loa (eye worm) hypothetical protein 0.0139 0.0866 0.0925
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0118 0.068 0.0662
Echinococcus granulosus nervana 2 0.0141 0.089 0.0873
Brugia malayi Protein kinase domain 0.0081 0.034 0.0354
Loa Loa (eye worm) SRC-1 0.0163 0.109 0.1169
Trichomonas vaginalis STE family protein kinase 0.0081 0.034 0.1439
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.0212 0.1529 0.1513
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0046 0.0024 0.0006
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0073 0.0268 0.0276
Plasmodium falciparum casein kinase 2, alpha subunit 0.0097 0.0486 0.4409
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0081 0.034 0.0322
Brugia malayi Pleckstrin Homology Domain 0.0045 0.0019 0.0005
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0061 0.0161 0.0159
Echinococcus multilocularis 3 phosphoinositide dependent protein kinase 1 0.0076 0.0293 0.0333
Echinococcus multilocularis casein kinase I alpha 0.0063 0.0182 0.0199
Echinococcus multilocularis myosin iiia 0.0079 0.0326 0.0373
Schistosoma mansoni cell adhesion molecule 0.011 0.0606 0.1025
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0118 0.068 0.2946
Brugia malayi Kinase associated domain 1 family protein 0.007 0.0241 0.0246
Echinococcus granulosus activin receptor type 0.0055 0.0111 0.0092
Trichomonas vaginalis CK1 family protein kinase 0.0063 0.0182 0.0742
Trypanosoma cruzi casein kinase, putative 0.0063 0.0182 0.081
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0715 0.3179
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0061 0.0161 0.0159
Trichomonas vaginalis STE family protein kinase 0.0081 0.034 0.1439
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Onchocerca volvulus 0.0069 0.0235 0.0457
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0203 0.1447 0.1736
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0163 0.109 0.1303
Entamoeba histolytica serine/threonine protein kinase STE20, putative 0.0079 0.0326 0.1342
Echinococcus multilocularis calcium activated potassium channel 0.009 0.0424 0.0492
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0101 0.0522 0.0611
Entamoeba histolytica protein kinase, putative 0.0047 0.0038 0.0061
Schistosoma mansoni serine/threonine kinase 0.0146 0.0935 0.1594
Trichomonas vaginalis AGC family protein kinase 0.0138 0.086 0.374
Brugia malayi Protein kinase domain containing protein 0.1059 0.9213 1
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0146 0.0935 0.1114
Schistosoma mansoni serine/threonine protein kinase 0.0187 0.1303 0.2232
Schistosoma mansoni protein kinase 0.0046 0.0024 0.0017
Schistosoma mansoni serine/threonine protein kinase 0.0078 0.0316 0.0522
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.068 0.3021
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0956 0.4168
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0076 0.0293 0.0302
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0024 0.0017
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0116 0.0662 0.0704
Loa Loa (eye worm) hypothetical protein 0.0136 0.0841 0.0898
Trichomonas vaginalis AGC family protein kinase 0.0076 0.0293 0.1231
Entamoeba histolytica protein kinase , putative 0.0149 0.0956 0.4144
Echinococcus granulosus tyrosine protein kinase ABL1 0.0306 0.2385 0.2371
Echinococcus granulosus tyrosine protein kinase Fyn 0.0163 0.109 0.1073
Brugia malayi C1-like domain containing protein 0.0152 0.0991 0.1061
Toxoplasma gondii AGC kinase 0.0066 0.0205 0.0825
Echinococcus granulosus c src tyrosine kinase 0.0096 0.0482 0.0464
Onchocerca volvulus Tyrosine kinase homolog 0.061 0.5138 1
Brugia malayi Cam kinase protein 1 0.0046 0.0024 0.0011
Echinococcus multilocularis nervana 2 0.0141 0.089 0.1059
Entamoeba histolytica protein kinase domain containing protein 0.0149 0.0956 0.4144
Echinococcus granulosus tyrosine protein kinase HCK 0.0102 0.0536 0.0519
Loa Loa (eye worm) hypothetical protein 0.0084 0.0374 0.039
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.0212 0.1529 0.1647
Echinococcus multilocularis mitogen activated protein kinase 14 0.0164 0.1098 0.1312
Echinococcus granulosus serine threonine protein kinase nrc 0.0161 0.1072 0.1055
Echinococcus multilocularis mitogen activated protein kinase 11 0.0164 0.1098 0.1312
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0066 0.0205 0.1727
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0078 0.0316 0.1405
Schistosoma mansoni hypothetical protein 0.007 0.0241 0.0393
Echinococcus granulosus mitogen activated protein kinase 0.0078 0.0316 0.0298
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0163 0.109 0.1303
Trichomonas vaginalis AGC family protein kinase 0.0294 0.2274 1
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.068 0.2944
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Brugia malayi Furin-like cysteine rich region family protein 0.0681 0.5786 0.6274
Trypanosoma cruzi Protein kinase B 0.0168 0.1129 0.5017
Schistosoma mansoni ephrin receptor 0.0109 0.0592 0.1001
Echinococcus multilocularis Immunoglobulin 0.0086 0.0392 0.0453
Loa Loa (eye worm) hypothetical protein 0.0102 0.0533 0.0564
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0306 0.2385 0.2877
Schistosoma mansoni tyrosine kinase 0.0495 0.4101 0.708
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0242 0.1807 0.1791
Entamoeba histolytica protein kinase domain containing protein 0.0097 0.0486 0.2054
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0046 0.0024 0.0007
Schistosoma mansoni tyrosine kinase 0.0096 0.0482 0.081
Echinococcus multilocularis c src tyrosine kinase 0.0096 0.0482 0.0563
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0956 0.4168
Schistosoma mansoni tyrosine kinase 0.0069 0.0235 0.0381
Echinococcus multilocularis NCK adaptor protein 0.0061 0.0161 0.0173
Loa Loa (eye worm) AUR protein kinase 0.0149 0.0956 0.1024
Brugia malayi Immunoglobulin I-set domain containing protein 0.0089 0.0417 0.0437
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0081 0.034 0.0391
Brugia malayi Protein kinase domain containing protein 0.0195 0.1378 0.1482
Echinococcus granulosus rho-associated protein kinase 1 0.0354 0.2819 0.2805
Schistosoma mansoni tyrosine kinase 0.0408 0.3307 0.5705
Trichomonas vaginalis CAMK family protein kinase 0.009 0.0424 0.181
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0024 0.0016
Loa Loa (eye worm) hypothetical protein 0.0093 0.0454 0.0477
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0138 0.086 0.3811
Echinococcus multilocularis tyrosine protein kinase Abl 0.0187 0.1304 0.1563
Echinococcus multilocularis mitogen activated protein kinase 3 0.0078 0.0316 0.0362
Entamoeba histolytica cell division protein kinase 2, putative 0.0118 0.068 0.2915
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0073 0.0268 0.044
Entamoeba histolytica protein kinase, putative 0.0149 0.0956 0.4144
Toxoplasma gondii casein kinase I 0.0063 0.0182 0.0722
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0046 0.0024 0.0007
Trypanosoma cruzi polo-like protein kinase, putative 0.0291 0.225 1
Onchocerca volvulus 0.0073 0.0271 0.0528
Echinococcus granulosus c-Jun N-terminal kinases 0.0284 0.2188 0.2173
Echinococcus multilocularis MAP kinase activated protein kinase 2 0.0433 0.3535 0.4275
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0935 0.1594
Echinococcus multilocularis tyrosine protein kinase Blk 0.0136 0.0843 0.1002
Entamoeba histolytica protein kinase domain containing protein 0.0122 0.0715 0.3073
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0164 0.1098 0.4879
Echinococcus multilocularis serine threonine protein kinase nrc serine threonine protein kinase gad 0.0161 0.1072 0.1281
Echinococcus multilocularis protein kinase shaggy 0.0129 0.0782 0.0928
Brugia malayi Variant SH3 domain containing protein 0.0073 0.0268 0.0276
Onchocerca volvulus 0.0069 0.0235 0.0457
Loa Loa (eye worm) hypothetical protein 0.0159 0.1046 0.1122
Brugia malayi serine/threonine kinase 12 0.0149 0.0956 0.1024
Trichomonas vaginalis conserved hypothetical protein 0.0061 0.0158 0.0633
Schistosoma mansoni protein kinase 0.0063 0.0182 0.029
Leishmania major protein kinase A catalytic subunit isoform 1 0.0066 0.0205 0.0813
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0129 0.0782 0.3457
Trichomonas vaginalis AGC family protein kinase 0.0294 0.2274 1
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0146 0.0935 0.0918
Brugia malayi phosphoinositide-dependent protein kinase I 0.0076 0.0293 0.0302
Loa Loa (eye worm) hypothetical protein 0.0164 0.1096 0.1176
Onchocerca volvulus 0.0159 0.1046 0.2037
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0066 0.0205 0.0804
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0424 0.0709
Loa Loa (eye worm) hypothetical protein 0.0107 0.0581 0.0616
Schistosoma mansoni protein kinase 0.0046 0.0024 0.0017
Schistosoma mansoni tyrosine kinase 0.0163 0.109 0.1863
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0183 0.1265 0.1249
Onchocerca volvulus 0.0069 0.0235 0.0457
Brugia malayi putative serine/threonine kinase SADA gamma 0.0046 0.0024 0.001
Schistosoma mansoni tyrosine kinase 0.0408 0.3307 0.5705
Loa Loa (eye worm) hypothetical protein 0.0098 0.0498 0.0525
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0758 0.3292
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0935 0.1594
Brugia malayi Protein kinase domain containing protein 0.0069 0.0235 0.0239
Echinococcus granulosus casein kinase i 0.0063 0.0182 0.0164
Trichomonas vaginalis AGC family protein kinase 0.0153 0.0992 0.4325
Trypanosoma cruzi polo-like protein kinase, putative 0.0291 0.225 1
Brugia malayi Stress-activated protein kinase jnk-1 0.0284 0.2188 0.2362
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0113 0.0631 0.067
Echinococcus granulosus serine:threonine protein kinase 0.0113 0.0631 0.0614
Trichomonas vaginalis AGC family protein kinase 0.0294 0.2274 1
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0118 0.068 0.2991
Echinococcus granulosus growth factor receptor bound protein 2 0.0061 0.0161 0.0143
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Loa Loa (eye worm) hypothetical protein 0.0126 0.0755 0.0805
Entamoeba histolytica PH domain containing protein kinase, putative 0.0072 0.0262 0.1058
Entamoeba histolytica p21-activated kinase 0.0087 0.0397 0.1658
Entamoeba histolytica casein kinase, putative 0.0097 0.0486 0.2054
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.068 0.3021
Loa Loa (eye worm) AGC/PKA protein kinase 0.0066 0.0205 0.0207
Loa Loa (eye worm) AGC/PKC/IOTA protein kinase 0.0161 0.1067 0.1144
Schistosoma mansoni serine/threonine protein kinase 0.0203 0.1447 0.2481
Schistosoma mansoni tyrosine kinase 0.0495 0.4101 0.708
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0046 0.0024 0.0002
Plasmodium vivax casein kinase 2, alpha subunit, putative 0.0097 0.0486 0.4409
Echinococcus granulosus mitogen activated protein kinase 14 0.0164 0.1098 0.1081
Loa Loa (eye worm) hypothetical protein 0.0089 0.0417 0.0437
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0046 0.0024 0.0002
Brugia malayi Protein kinase domain containing protein 0.0495 0.4101 0.4442
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0078 0.0316 0.1405
Onchocerca volvulus 0.0069 0.0235 0.0457
Loa Loa (eye worm) hypothetical protein 0.0066 0.0205 0.0207
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.1059 0.9213 1
Onchocerca volvulus 0.0139 0.0866 0.1685
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0066 0.0205 0.0911
Echinococcus multilocularis calcium:calmodulin dependent protein kinase I 0.0063 0.0182 0.0199
Schistosoma mansoni tyrosine kinase 0.0408 0.3307 0.5705
Schistosoma mansoni serine/threonine protein kinase 0.0149 0.0956 0.1632
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.068 0.0804
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0149 0.0956 0.8898
Echinococcus granulosus defective proboscis extension response 0.0086 0.0392 0.0374
Onchocerca volvulus 0.0093 0.0454 0.0883
Plasmodium falciparum serine/threonine protein kinase, putative 0.0149 0.0956 0.8898
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.1714 0.2944
Giardia lamblia Kinase, PLK 0.0291 0.225 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0061 0.0161 0.0254
Entamoeba histolytica serine/threonine protein kinase, putative 0.0291 0.225 0.9894
Schistosoma mansoni protein kinase 0.0149 0.0956 0.1632
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0113 0.0636 0.0675
Entamoeba histolytica protein kinase, putative 0.0129 0.0782 0.337
Echinococcus granulosus mitogen activated protein kinase 3 0.0078 0.0316 0.0298
Echinococcus multilocularis ephrin type A receptor 4 A 0.0109 0.0592 0.0697
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0156 0.1023 0.1006
Echinococcus multilocularis activin receptor type 0.0055 0.0111 0.0112
Echinococcus multilocularis neuroglian 0.0106 0.0565 0.0664
Schistosoma mansoni vesicular amine transporter 0.0086 0.0392 0.0653
Loa Loa (eye worm) AGC/PKN protein kinase 0.0146 0.0935 0.1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0055 0.0111 0.0396
Leishmania major protein kinase, putative 0.0046 0.0024 0.0002
Brugia malayi RhoGAP domain containing protein 0.0073 0.0268 0.0276
Brugia malayi Protein kinase domain containing protein 0.0146 0.0935 0.1
Echinococcus multilocularis serine:threonine protein kinase 3 0.0276 0.2111 0.2544
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0486 0.2086
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Entamoeba histolytica protein kinase, putative 0.0122 0.0715 0.3073
Entamoeba histolytica protein kinase, putative 0.0288 0.2217 0.9747
Echinococcus granulosus NDR protein kinase 0.0146 0.0935 0.0918
Echinococcus granulosus Glutaredoxin protein 5 0.0141 0.089 0.0873
Schistosoma mansoni serine/threonine protein kinase 0.0284 0.2188 0.3765
Echinococcus multilocularis cyclin dependent kinase 5 0.0118 0.068 0.0804
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0107 0.0581 0.0564
Brugia malayi serine/threonine-protein kinase 6 0.0149 0.0956 0.1024
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0046 0.0024 0.0006
Loa Loa (eye worm) STE/STE20/MST protein kinase 0.0276 0.2111 0.2279
Brugia malayi Variant SH3 domain containing protein 0.0061 0.0161 0.0159
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0066 0.0205 0.0804
Loa Loa (eye worm) camk/mapkapk/mapkapk protein kinase 0.0433 0.3535 0.3827
Plasmodium falciparum casein kinase 1 0.0063 0.0182 0.1511
Echinococcus granulosus tyrosine protein kinase Fyn 0.0163 0.109 0.1073
Loa Loa (eye worm) AGC/NDR protein kinase 0.0146 0.0935 0.1
Schistosoma mansoni protein kinase 0.0055 0.0111 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0291 0.225 0.3873
Trypanosoma brucei aurora B kinase 0.0149 0.0956 0.4144
Loa Loa (eye worm) CMGC/CK2 protein kinase 0.0097 0.0486 0.0512
Brugia malayi SH2 domain containing protein 0.0069 0.0235 0.0239
Trypanosoma brucei protein kinase, putative 0.0055 0.0111 0.0386
Echinococcus granulosus tyrosine protein kinase Fyn 0.0163 0.109 0.1073
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0149 0.0956 0.4144
Echinococcus multilocularis roundabout 2 0.0129 0.078 0.0925
Echinococcus multilocularis epidermal growth factor receptor 0.0443 0.3628 0.4389
Trypanosoma brucei polo-like protein kinase 0.0291 0.225 0.9894
Loa Loa (eye worm) hypothetical protein 0.0132 0.0809 0.0863
Echinococcus granulosus sodium:potassium dependent atpase beta subunit 0.0141 0.089 0.0873
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0127 0.0759 0.0742
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0424 0.0709
Plasmodium falciparum NIMA related kinase 1 0.0138 0.086 0.7974
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0046 0.0023 0.0005
Schistosoma mansoni tyrosine kinase 0.0272 0.2079 0.3576
Echinococcus granulosus insulin receptor 0.0495 0.4101 0.409
Brugia malayi Protein kinase domain containing protein 0.0294 0.2274 0.2456
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0152 0.0991 0.1061
Schistosoma mansoni serine/threonine protein kinase 0.0122 0.0715 0.1214
Entamoeba histolytica protein kinase, putative 0.0063 0.0183 0.0705
Echinococcus granulosus serine/threonine protein kinase 0.0168 0.1129 0.1112
Schistosoma mansoni tyrosine kinase 0.0262 0.1984 0.3412
Trichomonas vaginalis AGC family protein kinase 0.0294 0.2274 1
Brugia malayi MAP kinase sur-1 0.0078 0.0316 0.0328
Echinococcus multilocularis rac serine:threonine kinase 0.0168 0.1129 0.135
Entamoeba histolytica protein kinase, putative 0.0122 0.0715 0.3073
Entamoeba histolytica protein kinase, putative 0.0056 0.0115 0.0405
Echinococcus granulosus aurora kinase A 0.0149 0.0956 0.0939
Entamoeba histolytica protein kinase, putative 0.0149 0.0956 0.4144
Echinococcus granulosus tyrosine protein kinase Src64B 0.0163 0.109 0.1073
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0205 0.033
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0182 0.029
Trichomonas vaginalis AGC family protein kinase 0.0294 0.2274 1
Echinococcus granulosus protein kinase shaggy 0.0129 0.0782 0.0765
Schistosoma mansoni serine/threonine protein kinase 0.0232 0.1714 0.2944
Loa Loa (eye worm) TK protein kinase 0.0281 0.2157 0.2329
Echinococcus multilocularis casein kinase ii subunit alpha 0.0097 0.0486 0.0568
Loa Loa (eye worm) TK protein kinase 0.0136 0.0843 0.09
Plasmodium falciparum glycogen synthase kinase 3 0.0129 0.0782 0.7235
Schistosoma mansoni serine/threonine protein kinase 0.0063 0.0183 0.0291
Loa Loa (eye worm) hypothetical protein 0.0086 0.0392 0.041
Echinococcus granulosus ephrin type A receptor 4 A 0.0109 0.0592 0.0575
Entamoeba histolytica protein kinase, putative 0.0146 0.0935 0.4049
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0782 0.3397
Echinococcus multilocularis cyclin dependent kinase 0.0118 0.068 0.0804
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0291 0.225 0.2236
Trypanosoma brucei cdc2-related kinase 1 0.0118 0.068 0.2915
Echinococcus multilocularis insulin receptor 0.0495 0.4101 0.4963
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0078 0.0316 0.1405
Leishmania major protein kinase, putative 0.0079 0.0326 0.1356
Plasmodium vivax calcium-dependent protein kinase, putative 0.0046 0.0024 0.0005
Brugia malayi serine/threonine protein kinase 6 0.0149 0.0956 0.1024
Echinococcus multilocularis tyrosine protein kinase HCK 0.0102 0.0536 0.063
Trichomonas vaginalis AGC family protein kinase 0.0294 0.2274 1
Schistosoma mansoni serine/threonine protein kinase 0.0146 0.0935 0.1594
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0288 0.2217 0.2394
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.225 0.9895
Echinococcus multilocularis cyclin dependent kinase 1 0.0118 0.068 0.0804
Echinococcus granulosus calcium:calmodulin dependent protein kinase 0.0161 0.1072 0.1055
Giardia lamblia Kinase, CMGC GSK 0.0129 0.0782 0.3406
Schistosoma mansoni serine/threonine protein kinase 0.0076 0.0293 0.0482
Brugia malayi serine/threonine-protein kinase PAK 7 0.0248 0.1854 0.2
Brugia malayi Protein kinase domain containing protein 0.0076 0.0293 0.0302
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0284 0.2188 0.2362
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0242 0.1807 0.1948
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0078 0.0316 0.1299
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0122 0.0715 0.3179
Echinococcus multilocularis mitogen activated protein kinase 0.0078 0.0316 0.0362
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0086 0.0392 0.0653
Schistosoma mansoni protein kinase 0.0233 0.1723 0.2959
Onchocerca volvulus Serine\/threonine kinase homolog 0.0291 0.225 0.438
Onchocerca volvulus 0.0354 0.2819 0.5487
Schistosoma mansoni serine/threonine-protein kinase 0.0168 0.1129 0.1931
Schistosoma mansoni protein kinase 0.0097 0.0486 0.0817
Echinococcus granulosus twitchin 0.0126 0.0747 0.073
Entamoeba histolytica protein kinase, putative 0.0054 0.0096 0.032
Loa Loa (eye worm) hypothetical protein 0.0073 0.0271 0.0279
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0066 0.0205 0.0804
Loa Loa (eye worm) TK/ROR protein kinase 0.0055 0.0102 0.0095
Echinococcus multilocularis growth factor receptor bound protein 2 0.0061 0.0161 0.0173
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1265 0.2166
Echinococcus granulosus protein kinase C gamma type 0.0193 0.1359 0.1343
Loa Loa (eye worm) hypothetical protein 0.0046 0.0024 0.001
Trichomonas vaginalis CK1 family protein kinase 0.0063 0.0182 0.0742
Trichomonas vaginalis AGC family protein kinase 0.0066 0.0205 0.0842
Echinococcus multilocularis casein kinase I alpha 0.0063 0.0182 0.0199
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0066 0.0205 0.0207
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0759 0.129
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0156 0.1023 0.1096
Brugia malayi Sex muscle abnormal protein 5 0.0061 0.0161 0.0159
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0262 0.1984 0.1969
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0066 0.0205 0.0911
Loa Loa (eye worm) hypothetical protein 0.0093 0.0454 0.0477
Loa Loa (eye worm) TK/INSR protein kinase 0.0495 0.4101 0.4442
Entamoeba histolytica protein kinase domain containing protein 0.0129 0.0782 0.337
Brugia malayi protein kinase C3,putative 0.0154 0.1004 0.1076
Trypanosoma cruzi casein kinase, putative 0.0063 0.0182 0.081
Entamoeba histolytica casein kinase 1, putative 0.0063 0.0182 0.0704
Schistosoma mansoni ste20-related kinase 0.0217 0.1575 0.2703
Trichomonas vaginalis STE family protein kinase 0.0079 0.0326 0.1377
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Entamoeba histolytica protein kinase, putative 0.0294 0.2274 1
Trypanosoma cruzi cdc2-related kinase 1 0.0118 0.068 0.3021
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0935 0.4073
Schistosoma mansoni serine/threonine-protein kinase 0.0168 0.1129 0.1931
Schistosoma mansoni serine/threonine protein kinase 0.0212 0.1529 0.2625
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.068 0.2944
Echinococcus granulosus casein kinase I alpha 0.0063 0.0182 0.0164
Brugia malayi intracellular kinase 0.0129 0.0782 0.0834
Trypanosoma cruzi casein kinase II, putative 0.0097 0.0486 0.216
Echinococcus granulosus Protein kinase C brain isozyme 0.0232 0.1714 0.1698
Schistosoma mansoni protein kinase C mu 0.0152 0.0991 0.1691
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.225 0.9895
Trichomonas vaginalis STE family protein kinase 0.0138 0.086 0.374
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.225 0.9895
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0316 0.1335
Schistosoma mansoni serine/threonine protein kinase 0.0066 0.0205 0.033
Echinococcus granulosus serine:threonine protein kinase N2 0.0146 0.0935 0.0918
Trypanosoma brucei protein kinase, putative 0.0129 0.0782 0.337
Giardia lamblia Kinase, CMGC CDK 0.0118 0.068 0.2946
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0249 0.1865 0.2245
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Brugia malayi Temporarily assigned gene name protein 59 0.0147 0.0945 0.1011
Brugia malayi Protein kinase domain containing protein 0.0069 0.0235 0.0239
Brugia malayi Protein kinase domain containing protein 0.0118 0.068 0.0723
Giardia lamblia Kinase, STE STE20 0.0081 0.034 0.1419
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0073 0.0268 0.0304
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.068 0.0723
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0046 0.0024 0.0005
Echinococcus granulosus MAP kinase activated protein kinase 2 0.0433 0.3535 0.3523
Loa Loa (eye worm) hypothetical protein 0.0102 0.0533 0.0564
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0046 0.0024 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.225 0.9895
Schistosoma mansoni tyrosine kinase 0.0443 0.3628 0.6261
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0233 0.1723 0.1707
Plasmodium falciparum calcium-dependent protein kinase 2 0.0046 0.0024 0.0005
Loa Loa (eye worm) hypothetical protein 0.0198 0.1401 0.1507
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0163 0.109 0.1073
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0498 0.4126 0.4115
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0161 0.1072 0.4764
Plasmodium vivax rac-beta serine/threonine protein kinase, putative 0.0161 0.1072 1
Echinococcus granulosus cyclin dependent kinase 1 0.0118 0.068 0.0662
Schistosoma mansoni protein kinase 0.0081 0.034 0.0563
Brugia malayi P38 map kinase family protein 2 0.0164 0.1098 0.1177
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0163 0.109 0.1303
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0096 0.0482 0.081
Entamoeba histolytica protein kinase 2, putative 0.0161 0.1072 0.4658
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0081 0.034 0.0322
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0066 0.0205 0.0226
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0086 0.0392 0.0453
Brugia malayi Protein kinase domain containing protein 0.0146 0.0935 0.1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0046 0.0024 0.0011
Schistosoma mansoni growth factor receptor-bound protein 0.0061 0.0161 0.0254
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Echinococcus granulosus protein kinase c epsilon type 0.0187 0.1303 0.1286
Echinococcus multilocularis casein kinase I alpha 0.0063 0.0182 0.0199
Plasmodium falciparum calcium-dependent protein kinase 5 0.0046 0.0024 0.0005
Onchocerca volvulus 0.0063 0.0182 0.0355
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0149 0.0956 0.114
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.225 0.9895
Echinococcus granulosus dual specificity 0.0122 0.0715 0.0698
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0291 0.225 0.2713
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0187 0.1303 0.14
Loa Loa (eye worm) hypothetical protein 0.0113 0.0631 0.067
Echinococcus granulosus tyrosine protein kinase Blk 0.0136 0.0843 0.0825
Schistosoma mansoni tyrosine kinase 0.0096 0.0482 0.081
Echinococcus multilocularis tyrosine protein kinase Srms 0.0136 0.0843 0.1002
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0149 0.0956 0.4144
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0163 0.109 0.1303
Trichomonas vaginalis serine/threonine-protein kinase sgk, putative 0.0126 0.0753 0.3266
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0149 0.0956 0.4144
Schistosoma mansoni serine/threonine protein kinase 0.0099 0.0501 0.0843
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0203 0.1447 0.2816
Trypanosoma brucei STE20-like serine/threonine-protein kinase 1, putative 0.0079 0.0326 0.1342
Leishmania major protein kinase A catalytic subunit 0.0066 0.0205 0.0813
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0046 0.0024 0.0005
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0129 0.0782 0.0928
Echinococcus granulosus epidermal growth factor receptor 0.0443 0.3628 0.3616
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0136 0.0843 0.1002
Echinococcus multilocularis casein kinase I delta 0.0063 0.0182 0.0199
Entamoeba histolytica protein kinase, putative 0.0046 0.0024 0.0002
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0086 0.0392 0.0653
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0063 0.0182 0.0182
Echinococcus granulosus cyclin dependent kinase 5 0.0118 0.068 0.0662
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0046 0.0024 0.0007
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0078 0.0316 0.1313
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0055 0.0102 0.0101
Echinococcus granulosus raf serine:threonine protein kinase 0.0075 0.0283 0.0265
Echinococcus multilocularis serine:threonine protein kinase N2 0.0146 0.0935 0.1114
Schistosoma mansoni tyrosine kinase 0.0163 0.109 0.1863
Echinococcus granulosus epidermal growth factor receptor 0.0681 0.5786 0.5778
Brugia malayi hypothetical protein 0.0069 0.0235 0.0239
Plasmodium falciparum protein kinase, putative 0.0055 0.0111 0.0829
Echinococcus multilocularis mitogen activated protein kinase 14 0.0164 0.1098 0.1312
Brugia malayi map kinase activated protein kinase protein 2 0.0433 0.3535 0.3827
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.225 0.9895
Trichomonas vaginalis AGC family protein kinase 0.0076 0.0293 0.1231
Entamoeba histolytica PH domain containing protein kinase, putative 0.0168 0.1129 0.4911
Trypanosoma cruzi rac serine-threonine kinase, putative 0.0168 0.1129 0.5017
Echinococcus multilocularis serine threonine protein kinase 0.0193 0.1359 0.163
Echinococcus multilocularis 0.0198 0.1408 0.1689
Brugia malayi Protein kinase domain containing protein 0.0069 0.0235 0.0239
Loa Loa (eye worm) hypothetical protein 0.0086 0.0392 0.041
Entamoeba histolytica casein kinase, putative 0.0063 0.0182 0.0704
Echinococcus granulosus NCK adaptor protein 0.0061 0.0161 0.0143
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0081 0.034 0.0391
Giardia lamblia Kinase, AGC PKA 0.0066 0.0205 0.0813
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Entamoeba histolytica protein kinase, putative 0.0062 0.0172 0.0658
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0078 0.0316 0.1405
Toxoplasma gondii AGC kinase 0.0066 0.0205 0.0825
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0046 0.0024 0.0005
Brugia malayi Protein kinase domain containing protein 0.009 0.0424 0.0445
Plasmodium vivax protein kinase Crk2 0.0118 0.068 0.6259
Brugia malayi Casein kinase II, alpha chain 0.0097 0.0486 0.0512
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0183 0.1265 0.1515
Trypanosoma brucei rac serine-threonine kinase, putative 0.0294 0.2274 1
Echinococcus multilocularis N chimaerin 0.0073 0.0268 0.0304
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Schistosoma mansoni nck2/grb4 0.0061 0.0161 0.0254
Brugia malayi protein kinase C II. 0.0187 0.1303 0.14
Giardia lamblia Kinase, NEK 0.0138 0.086 0.3754
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0122 0.0715 0.3073
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.068 0.1152
Plasmodium falciparum calcium-dependent protein kinase 4 0.0046 0.0024 0.0005
Brugia malayi casein kinase I 0.0063 0.0182 0.0182
Giardia lamblia Kinase, AGC AKT 0.0116 0.0662 0.2866
Giardia lamblia Kinase, AGC PKA 0.0161 0.1072 0.4708
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0069 0.0235 0.0263
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0078 0.0316 0.1313
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0045 0.0015 0.0065
Schistosoma mansoni tyrosine kinase 0.0222 0.1617 0.2777
Echinococcus granulosus tyrosine kinase 0.0136 0.0843 0.0825
Schistosoma mansoni vav2 0.0079 0.0326 0.0539
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0046 0.0024 0.0011
Echinococcus granulosus myotubularin protein 13 0.0045 0.0019 0.0001
Loa Loa (eye worm) TK/ABL protein kinase 0.0306 0.2385 0.2577
Schistosoma mansoni protein kinase 0.0056 0.0115 0.0174
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0291 0.225 1
Echinococcus granulosus 3-phosphoinositide-dependent protein kinase 1 0.0076 0.0293 0.0275
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0203 0.1447 0.1557
Brugia malayi Immunoglobulin I-set domain containing protein 0.0281 0.2157 0.2329
Onchocerca volvulus 0.0555 0.4643 0.9038
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0163 0.109 0.1303
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0146 0.0935 0.1114
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0129 0.0782 0.0765
Schistosoma mansoni serine/threonine protein kinase 0.0156 0.1023 0.1747
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0163 0.109 0.1073
Entamoeba histolytica hypothetical protein 0.0122 0.0715 0.3073
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0066 0.0205 0.0825
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0935 0.4073
Echinococcus multilocularis tyrosine kinase 0.0069 0.0235 0.0263
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0127 0.0759 0.0901
Trypanosoma cruzi casein kinase, putative 0.0063 0.0182 0.081
Giardia lamblia Kinase, CMGC CK2 0.0097 0.0486 0.2076
Entamoeba histolytica protein kinase, putative 0.0076 0.0293 0.1195
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0129 0.0782 0.133
Echinococcus granulosus tyrosine protein kinase Lyn 0.0184 0.1272 0.1256
Echinococcus granulosus casein kinase I delta 0.0063 0.0182 0.0164
Loa Loa (eye worm) hypothetical protein 0.0061 0.0158 0.0155
Entamoeba histolytica protein kinase, putative 0.0081 0.034 0.1404
Trichomonas vaginalis CK1 family protein kinase 0.0063 0.0182 0.0742
Echinococcus multilocularis Glutaredoxin protein 5 0.0141 0.089 0.1059
Echinococcus granulosus tyrosine protein kinase shark 0.0069 0.0235 0.0216
Loa Loa (eye worm) hypothetical protein 0.0087 0.0394 0.0412
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0203 0.1447 0.1431
Echinococcus multilocularis tyrosine protein kinase shark 0.0069 0.0235 0.0263
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0486 0.2086
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0063 0.0182 0.0182
Schistosoma mansoni serine/threonine kinase 0.009 0.0424 0.0709
Schistosoma mansoni serine/threonine protein kinase 0.0354 0.2819 0.4859
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0203 0.1447 0.1557
Echinococcus granulosus mitogen activated protein kinase 11 0.0164 0.1098 0.1081
Echinococcus multilocularis protein kinase c iota type 0.028 0.2149 0.259
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0055 0.0102 0.0083
Schistosoma mansoni growth factor receptor-bound protein 0.0061 0.0161 0.0254
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0486 0.2086
Trypanosoma cruzi casein kinase, putative 0.0063 0.0182 0.081
Loa Loa (eye worm) TK protein kinase 0.0102 0.0536 0.0567
Echinococcus granulosus fibroblast growth factor receptor 4 0.0262 0.1984 0.1969
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0024 0.0016
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0081 0.034 0.0322
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0111 0.0492
Echinococcus multilocularis myotubularin protein 13 0.0045 0.0019 0.0001
Echinococcus multilocularis sodium:potassium dependent atpase beta subunit 0.0141 0.089 0.1059
Plasmodium falciparum calcium-dependent protein kinase 1 0.0046 0.0024 0.0005
Schistosoma mansoni tyrosine kinase 0.0071 0.0254 0.0414
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0043
Schistosoma mansoni serine/threonine protein kinase 0.0118 0.068 0.1152
Echinococcus multilocularis hypothetical protein 0.007 0.0241 0.0271
Trichomonas vaginalis AGC family protein kinase 0.0294 0.2274 1
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0078 0.0316 0.0328
Trichomonas vaginalis AGC family protein kinase 0.0076 0.0293 0.1231
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0232 0.1714 0.2061
Entamoeba histolytica PH domain containing protein kinase, putative 0.0168 0.1129 0.4911
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0486 0.2086
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0136 0.0843 0.0825
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0066 0.0205 0.1727
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0129 0.0782 0.3406
Giardia lamblia Kinase, CK1 Casein kinase 0.0063 0.0182 0.0711
Echinococcus multilocularis protein kinase c epsilon type 0.0187 0.1303 0.1561
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0063 0.0178 0.0177
Leishmania major protein kinase, putative 0.0149 0.0956 0.4189
Loa Loa (eye worm) AGC/PKA protein kinase 0.0066 0.0205 0.0207
Giardia lamblia Kinase, STE STE20 0.0079 0.0326 0.1356
Brugia malayi Protein kinase c protein 2 0.0106 0.0569 0.0602
Entamoeba histolytica protein kinase, putative 0.0294 0.2274 1
Loa Loa (eye worm) hypothetical protein 0.0126 0.0755 0.0805
Echinococcus granulosus Immunoglobulin 0.0086 0.0392 0.0374
Echinococcus multilocularis serine:threonine protein kinase N2 0.0146 0.0935 0.1114
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0956 0.4168
Brugia malayi casein kinase 1, delta 0.0063 0.0182 0.0182
Plasmodium falciparum RAC-beta serine/threonine protein kinase 0.0161 0.1072 1
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0024 0.0016
Trichomonas vaginalis AGC family protein kinase 0.0146 0.0935 0.4073
Giardia lamblia Kinase, NEK 0.0138 0.086 0.3754
Loa Loa (eye worm) hypothetical protein 0.0045 0.0019 0.0005
Brugia malayi Tyrosine-protein kinase abl-1 0.0146 0.0936 0.1001
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0156 0.1023 0.1221
Loa Loa (eye worm) hypothetical protein 0.0159 0.1046 0.1122
Loa Loa (eye worm) TK/EPH protein kinase 0.0129 0.0774 0.0826
Echinococcus granulosus tyrosine protein kinase Src42A 0.0101 0.0522 0.0504
Entamoeba histolytica protein kinase domain containing protein 0.0055 0.0111 0.0386
Trichomonas vaginalis STE family protein kinase 0.0081 0.034 0.1439
Trichomonas vaginalis STE family protein kinase 0.0056 0.0115 0.0444
Entamoeba histolytica protein kinase, putative 0.0063 0.0183 0.0705
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0118 0.068 0.2946
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0149 0.0956 0.0939
Echinococcus granulosus serine:threonine protein kinase 0.0113 0.0631 0.0614
Trypanosoma brucei casein kinase I, isoform 2 0.0063 0.0182 0.0704
Trypanosoma cruzi STE/STE20 serine/threonine-protein kinase, putative 0.0079 0.0326 0.1448
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0248 0.1854 0.2
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0066 0.0205 0.0187
Loa Loa (eye worm) hypothetical protein 0.0305 0.2374 0.2564
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Schistosoma mansoni adapter molecule crk 0.0061 0.0161 0.0254
Brugia malayi STE20-like kinase MST 0.0276 0.2111 0.2279
Trichomonas vaginalis CMGC family protein kinase 0.0118 0.068 0.2944
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0163 0.109 0.1303
Plasmodium falciparum calcium-dependent protein kinase 3 0.0046 0.0024 0.0005
Loa Loa (eye worm) TK/EGFR protein kinase 0.0681 0.5786 0.6274
Echinococcus multilocularis dual specificity 0.0122 0.0715 0.0847
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Echinococcus multilocularis mitogen activated protein kinase 11 0.0164 0.1098 0.1312
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0066 0.0205 0.0226
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.009 0.0424 0.0445
Echinococcus granulosus tyrosine protein kinase Src42A 0.0163 0.109 0.1073
Echinococcus multilocularis raf serine:threonine protein kinase 0.0075 0.0283 0.0322
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0164 0.1098 0.1177
Brugia malayi Protein kinase domain containing protein 0.0113 0.0631 0.067
Echinococcus granulosus tyrosine protein kinase Srms 0.0069 0.0235 0.0216
Trypanosoma brucei Casein kinase II 0.0097 0.0486 0.2054
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0164 0.1098 0.4824
Brugia malayi Protein kinase domain containing protein 0.0069 0.0235 0.0239
Echinococcus granulosus tyrosine kinase 0.0069 0.0235 0.0216
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0046 0.0024 0.0106
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0443 0.3628 0.3616
Schistosoma mansoni serine/threonine protein kinase 0.0242 0.1807 0.3105
Loa Loa (eye worm) AGC/PDK1 protein kinase 0.0076 0.0293 0.0302
Trichomonas vaginalis CMGC family protein kinase 0.0078 0.0316 0.1335
Trypanosoma cruzi p21-activated kinase 3, putative 0.0045 0.0015 0.0065
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0024 0.0041
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0156 0.1023 0.1096
Schistosoma mansoni serine/threonine protein kinase 0.0075 0.0283 0.0466
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0164 0.1098 0.4773
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0138 0.086 0.7974
Trypanosoma cruzi cdc2-related kinase 3 0.0118 0.068 0.3021
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0066 0.0205 0.0187
Brugia malayi protein-tyrosine kinase 0.0136 0.0843 0.09
Entamoeba histolytica protein kinase, putative 0.0062 0.0172 0.0658
Schistosoma mansoni serine/threonine protein kinase 0.0183 0.1265 0.2166
Trichomonas vaginalis CAMK family protein kinase 0.0127 0.0758 0.3292
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0122 0.0715 0.3106
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0163 0.109 0.1303
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0066 0.0205 0.0911
Giardia lamblia Kinase, CMGC GSK 0.0129 0.0782 0.3406
Echinococcus granulosus casein kinase I alpha 0.0063 0.0182 0.0164
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0291 0.225 0.243
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0349 0.2775 0.3001
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.0148 0.095 0.0933
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0203 0.1447 0.1557
Trichomonas vaginalis CMGC family protein kinase 0.0097 0.0486 0.2086
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.0212 0.1529 0.1836
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0046 0.0024 0.0106
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0129 0.0782 0.0834
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0046 0.0024 0.0011
Brugia malayi Tyrosine-protein kinase abl-1 0.0187 0.1304 0.1402
Giardia lamblia Kinase, CMGC MAPK 0.0078 0.0316 0.1313
Giardia lamblia Aurora kinase 0.0149 0.0956 0.4189
Loa Loa (eye worm) hypothetical protein 0.0046 0.0024 0.0011
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0152 0.0991 0.1061
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0111 0.0386
Brugia malayi Immunoglobulin I-set domain containing protein 0.0698 0.5938 0.6439
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0046 0.0024 0.0007
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0262 0.1984 0.239
Schistosoma mansoni tyrosine kinase 0.0075 0.0292 0.048
Trichomonas vaginalis AGC family protein kinase 0.0149 0.0956 0.4168
Onchocerca volvulus 0.0069 0.0235 0.0457
Schistosoma mansoni nephrin 0.0108 0.059 0.0997
Plasmodium falciparum protein kinase 5 0.0118 0.068 0.6259
Schistosoma mansoni tyrosine kinase 0.0681 0.5786 1
Loa Loa (eye worm) TK/FER protein kinase 0.0069 0.0235 0.0239
Echinococcus multilocularis epidermal growth factor receptor 0.0681 0.5786 0.7013
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0073 0.0268 0.044
Schistosoma mansoni protein kinase 0.0081 0.034 0.0563
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0146 0.0935 0.0918
Trichomonas vaginalis CMGC family protein kinase 0.0129 0.0782 0.3397
Trichomonas vaginalis CAMK family protein kinase 0.0291 0.225 0.9895
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0242 0.1807 0.2174
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0233 0.1723 0.2072
Giardia lamblia Kinase, NEK 0.0138 0.086 0.3754
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0249 0.1865 0.185
Schistosoma mansoni atypical protein kinase C 0.0287 0.2212 0.3808
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0129 0.0782 0.3476
Onchocerca volvulus 0.0069 0.0235 0.0457
Plasmodium vivax unspecified product 0.0097 0.0486 0.4409
Echinococcus multilocularis aurora kinase A 0.0149 0.0956 0.114
Echinococcus multilocularis serine:threonine protein kinase 0.0113 0.0631 0.0745
Schistosoma mansoni serine/threonine protein kinase 0.009 0.0424 0.0709
Echinococcus granulosus roundabout 2 0.0129 0.078 0.0763
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0055 0.0111 0.0492
Echinococcus granulosus cyclin dependent kinase 0.0118 0.068 0.0662
Brugia malayi serine/threonine-protein kinase plk-2 0.0291 0.225 0.243
Echinococcus multilocularis PAK box P21 Rho binding 0.0056 0.0115 0.0117
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0063 0.0182 0.081
Loa Loa (eye worm) AUR protein kinase 0.0149 0.0956 0.1024
Trichomonas vaginalis CAMK family protein kinase 0.0113 0.0631 0.2729
Toxoplasma gondii AGC kinase 0.0288 0.2217 1
Schistosoma mansoni serine/threonine protein kinase 0.0127 0.0759 0.129
Trypanosoma brucei cdc2-related kinase 3 0.0118 0.068 0.2915
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0118 0.068 0.0723

Activities

Activity type Activity value Assay description Source Reference
k cat/Km (binding) < 0.2 M-1 s-1 Specificity constant is determined from the ratio of the inactivation rate constants (Kcat/Km)of the cathepsin B. ChEMBL. 9548822
k cat/Km (binding) < 0.2 M-1 s-1 Specificity constant is determined from the ratio of the inactivation rate constants (Kcat/Km)of the cathepsin B. ChEMBL. 9548822
k cat/Km (binding) = 0.3 M-1 s-1 Specificity constant is determined from the ratio of the inactivation rate constants (Kcat/Km)of the papaine. ChEMBL. 9548822
k cat/Km (binding) = 0.3 M-1 s-1 Specificity constant is determined from the ratio of the inactivation rate constants (Kcat/Km)of the papaine. ChEMBL. 9548822
k2/Ki (binding) = 7730 M-1 s-1 The apparent second-order rate constant for inactivation of bovine cathepsin B enzyme. Apparent rate constant was determined from replots of Kobs vs [I] using at least 5 values of [I]. ChEMBL. 9548822
k2/Ki (binding) = 7730 M-1 s-1 The apparent second-order rate constant for inactivation of bovine cathepsin B enzyme. Apparent rate constant was determined from replots of Kobs vs [I] using at least 5 values of [I]. ChEMBL. 9548822
k2/Ki (binding) = 67600 M-1 s-1 The apparent second-order rate constant for inactivation of papain enzyme. Apparent rate constant was determined from replots of Kobs vs [I] using at least 5 values of [I]. ChEMBL. 9548822
k2/Ki (binding) = 67600 M-1 s-1 The apparent second-order rate constant for inactivation of papain enzyme. Apparent rate constant was determined from replots of Kobs vs [I] using at least 5 values of [I]. ChEMBL. 9548822
ki/Ki (binding) > 11000 M-1 s-1 The compound was tested for Rate of Inhibition of Papain . ChEMBL. 1447732
ki/Ki (binding) > 11000 M-1 s-1 The compound was tested for Rate of Inhibition of Papain . ChEMBL. 1447732

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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