Detailed information for compound 557855

Basic information

Technical information
  • TDR Targets ID: 557855
  • Name: tris(4-chlorophenyl)methanol
  • MW: 363.665 | Formula: C19H13Cl3O
  • H donors: 1 H acceptors: 1 LogP: 6.1 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(c1ccc(cc1)Cl)(c1ccc(cc1)Cl)c1ccc(cc1)Cl
  • InChi: 1S/C19H13Cl3O/c20-16-7-1-13(2-8-16)19(23,14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,23H
  • InChiKey: BPFKTJMHOWDJKI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3010-80-8
  • ZINC05226822
  • ST5411441
  • 4,4',4''-Trichlorotrityl alcohol
  • EINECS 221-137-4

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni smad 0.0024 0.0102 0.0101
Schistosoma mansoni adenoreceptor 0.01 0.064 0.0639
Echinococcus granulosus Diacylglycerol kinase theta 0.0038 0.0198 0.0198
Schistosoma mansoni intermediate filament proteins 0.0027 0.0122 0.0121
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0054
Echinococcus granulosus biogenic amine 5HT receptor 0.01 0.064 0.064
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.001 0.0003 0.0005
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0038 0.0198 0.781
Onchocerca volvulus 0.01 0.064 0.172
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0117 0.3677
Brugia malayi hypothetical protein 0.0535 0.3718 1
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0104 0.0606
Echinococcus multilocularis Protein lozenge 0.0067 0.0406 0.0406
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.01 0.064 0.0639
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0011
Echinococcus granulosus guanine nucleotide binding protein G protein 0.001 0.0003 0.0003
Echinococcus granulosus thyrotropin releasing hormone receptor 0.01 0.064 0.064
Echinococcus granulosus guanine nucleotide binding protein subunit 0.001 0.0003 0.0003
Brugia malayi mothers against decapentaplegic homolog 3 0.0011 0.0007 0.0016
Echinococcus granulosus fmrfamide receptor 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0229 0.1552 0.2283
Echinococcus multilocularis tumor protein p63 0.0342 0.2355 0.2355
Echinococcus granulosus rhodopsin orphan GPCR 0.01 0.064 0.064
Echinococcus multilocularis neuropeptide Y receptor 0.01 0.064 0.064
Brugia malayi Diacylglycerol kinase protein 2 0.0038 0.0198 0.053
Schistosoma mansoni amine GPCR 0.01 0.064 0.0639
Echinococcus granulosus dnaJ subfamily B 0.04 0.276 0.276
Onchocerca volvulus 0.01 0.064 0.172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0031 0.0147 0.0861
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus granulosus FTZ F1 alpha 0.0021 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni myosin xvIII 0.01 0.064 0.0639
Brugia malayi Serotonin receptor 0.01 0.064 0.172
Brugia malayi hypothetical protein 0.0026 0.0117 0.0313
Schistosoma mansoni amine GPCR 0.01 0.064 0.0639
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0198 0.1168
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0324 0.0868
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.001 0.0023
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.01 0.064 0.0941
Echinococcus granulosus neuropeptide s receptor 0.01 0.064 0.064
Echinococcus granulosus guanine nucleotide binding protein subunit 0.001 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.01 0.064 0.064
Trichomonas vaginalis bmru protein, putative 0.0038 0.0198 0.1168
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.001 0.0023
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.01 0.064 0.064
Schistosoma mansoni hypothetical protein 0.01 0.064 0.0639
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.01 0.064 0.064
Schistosoma mansoni opsin-like receptor 0.01 0.064 0.0639
Echinococcus multilocularis sex peptide receptor 0.01 0.064 0.064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Schistosoma mansoni smad 0.0011 0.0007 0.0006
Onchocerca volvulus 0.0028 0.0129 0.0344
Echinococcus granulosus lamin 0.0027 0.0122 0.0122
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0023 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Trichomonas vaginalis sphingosine kinase, putative 0.0038 0.0198 0.1168
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0102 0.0101
Echinococcus multilocularis tar DNA binding protein 0.0135 0.0888 0.0888
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.008 0.0213
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.001 0.0003 0.0005
Schistosoma mansoni hypothetical protein 0.0038 0.0198 0.0197
Echinococcus multilocularis serotonin receptor 0.01 0.064 0.064
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Trichomonas vaginalis diacylglycerol kinase, putative 0.0038 0.0198 0.1168
Schistosoma mansoni thyroid hormone receptor 0.0021 0.008 0.0079
Schistosoma mansoni sphingoid long chain base kinase 0.097 0.6801 0.6801
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0888 0.0886
Echinococcus granulosus biogenic amine 5HT receptor 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus multilocularis allatostatin A receptor 0.01 0.064 0.064
Brugia malayi hypothetical protein 0.0038 0.0198 0.053
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.0154 0.0154
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0187 0.1102
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.01 0.064 0.0639
Brugia malayi hypothetical protein 0.0011 0.001 0.0023
Schistosoma mansoni hypothetical protein 0.0728 0.5086 0.5085
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus multilocularis tachykinin peptides receptor 99D 0.01 0.064 0.064
Echinococcus multilocularis dro:myosuppressin receptor 0.01 0.064 0.064
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0046 0.0253 0.0253
Brugia malayi hypothetical protein 0.0229 0.1552 0.4174
Onchocerca volvulus 0.01 0.064 0.172
Echinococcus granulosus G protein coupled receptor 139 0.01 0.064 0.064
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.008 0.0213
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.008 0.008
Brugia malayi MH2 domain containing protein 0.0024 0.0102 0.0272
Echinococcus granulosus g-protein coupled receptor 0.01 0.064 0.064
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0001 0.0001
Onchocerca volvulus 0.01 0.064 0.172
Echinococcus granulosus neuropeptide receptor 0.01 0.064 0.064
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0239 0.1624 0.1623
Brugia malayi diacylglycerol kinase 0.0038 0.0198 0.053
Plasmodium vivax diacylglycerol kinase, putative 0.0038 0.0198 1
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0046 0.0253 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0001 0.0001
Loa Loa (eye worm) G protein alpha subunit 3 0.001 0.0003 0.0005
Onchocerca volvulus 0.01 0.064 0.172
Entamoeba histolytica diacylglycerol kinase, putative 0.0038 0.0198 0.0287
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0046 0.0253 0.0367
Echinococcus multilocularis Diacylglycerol kinase theta 0.0038 0.0198 0.0198
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0162 0.6373
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0104 0.0606
Brugia malayi Dopamine receptor protein 1 0.01 0.064 0.172
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.0154 0.0154
Trichomonas vaginalis rotamase, putative 0.0033 0.0162 0.0953
Brugia malayi hypothetical protein 0.01 0.064 0.172
Echinococcus multilocularis geminin 0.0728 0.5086 0.5086
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0117 0.4588
Loa Loa (eye worm) hypothetical protein 0.0032 0.0154 0.0226
Trichomonas vaginalis set domain proteins, putative 0.0246 0.1671 1
Leishmania major diacylglycerol kinase-like protein 0.0038 0.0198 0.781
Brugia malayi MH1 domain containing protein 0.0013 0.0026 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0105 0.0608
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0039 0.1438
Echinococcus multilocularis rhodopsin orphan GPCR 0.01 0.064 0.064
Echinococcus multilocularis mothers against decapentaplegic 2 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Brugia malayi ecdysteroid receptor 0.0021 0.008 0.0213
Loa Loa (eye worm) hypothetical protein 0.0155 0.1025 0.1508
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.008 0.008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0239 0.1624 0.2388
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0014
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.008 0.008
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0315 1
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.001 0.0003 0.0002
Schistosoma mansoni neuropeptide receptor 0.01 0.064 0.0639
Brugia malayi Muscleblind-like protein 0.0155 0.1025 0.2755
Echinococcus multilocularis mothers against decapentaplegic 6 0.0011 0.0007 0.0007
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0154 0.0154
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.014 0.0819
Brugia malayi MH1 domain containing protein 0.0024 0.0102 0.0272
Brugia malayi hypothetical protein 0.0017 0.0051 0.0134
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0046 0.0253 1
Echinococcus multilocularis neuropeptide Y receptor 0.01 0.064 0.064
Brugia malayi neuropeptide F receptor 0.01 0.064 0.172
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0123 0.0719
Loa Loa (eye worm) hypothetical protein 0.0038 0.0199 0.0293
Echinococcus multilocularis muscleblind protein 0.0155 0.1025 0.1025
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.017 0.1002
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Onchocerca volvulus Mothers against decapentaplegic homolog 0.0011 0.0007 0.0016
Brugia malayi G-protein alpha subunit 0.001 0.0003 0.0005
Schistosoma mansoni cpg binding protein 0.003 0.014 0.0139
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni opsin-like receptor 0.01 0.064 0.0639
Echinococcus granulosus geminin 0.0728 0.5086 0.5086
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0118
Echinococcus granulosus tar DNA binding protein 0.0135 0.0888 0.0888
Loa Loa (eye worm) diacylglycerol kinase 2 0.0038 0.0198 0.0291
Onchocerca volvulus 0.0047 0.0261 0.07
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.001 0.0003 0.0005
Brugia malayi Eye-specific diacylglycerol kinase 0.0038 0.0198 0.053
Loa Loa (eye worm) hypothetical protein 0.0027 0.0122 0.0179
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.008 0.0213
Echinococcus multilocularis fmrfamide receptor 0.01 0.064 0.064
Echinococcus multilocularis acylglycerol kinase, mitochondrial 0.0038 0.0198 0.0198
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0055 0.0081
Trypanosoma cruzi Diacylglycerol kinase catalytic domain containing protein, putative 0.0038 0.0198 0.781
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.01 0.064 0.064
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0055 0.0145
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.01 0.064 0.172
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.001 0.0003 0.0003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0123 0.0719
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0055 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.036 0.0359
Onchocerca volvulus 0.01 0.064 0.172
Brugia malayi nuclear hormone receptor 0.0021 0.008 0.0213
Trichomonas vaginalis rotamase, putative 0.0034 0.0168 0.0986
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0001 0.0001
Echinococcus multilocularis expressed protein 0.001 0.0003 0.0003
Schistosoma mansoni GTP-binding protein alpha subunit 0.001 0.0003 0.0002
Brugia malayi hypothetical protein 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0291
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0117 0.4588
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.001 0.0003 0.0002
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0012 0.0014 0.0014
Echinococcus granulosus neuropeptide Y receptor 0.01 0.064 0.064
Brugia malayi Tachykinin-like peptides receptor 99D 0.01 0.064 0.172
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0154 0.0152
Echinococcus multilocularis sphingosine kinase 1 0.097 0.6801 0.6801
Entamoeba histolytica diacylglycerol kinase, putative 0.0038 0.0198 0.0287
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0253 0.1497
Brugia malayi steroid hormone receptor 0.0021 0.008 0.0213
Trypanosoma brucei hypothetical protein, conserved 0.0038 0.0198 0.781
Trichomonas vaginalis bmru protein, putative 0.0038 0.0198 0.1168
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.001 0.0003 0.0002
Plasmodium vivax SET domain protein, putative 0.0032 0.0154 0.4484
Onchocerca volvulus 0.0027 0.0122 0.0325
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0039 0.1438
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.001 0.001
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0054
Trypanosoma brucei Sphingosine kinase 0.0038 0.0198 0.781
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0105 0.0608
Loa Loa (eye worm) transcription factor SMAD2 0.0356 0.2454 0.3608
Echinococcus granulosus neuropeptide receptor 0.01 0.064 0.064
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.01 0.064 0.0639
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni biogenic amine receptor 0.01 0.064 0.0639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.008 0.0118
Mycobacterium ulcerans hypothetical protein 0.097 0.6801 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0187 0.1102
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0102 0.0102
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0888 0.0886
Echinococcus granulosus hypothetical protein 0.01 0.064 0.064
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.01 0.064 0.064
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0039 0.0057
Schistosoma mansoni biogenic amine (dopamine) receptor 0.01 0.064 0.0639
Schistosoma mansoni diacylglycerol kinase theta 0.0038 0.0198 0.0197
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.008 0.008
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0033 0.0162 0.0234
Brugia malayi follicle stimulating hormone receptor 0.01 0.064 0.172
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.008 0.008
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.008 0.0213
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.01 0.064 0.064
Schistosoma mansoni biogenic amine (dopamine) receptor 0.01 0.064 0.0639
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.01 0.064 0.064
Schistosoma mansoni cellular tumor antigen P53 0.005 0.0285 0.0284
Brugia malayi intermediate filament protein 0.0027 0.0122 0.0325
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.001 0.0003 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.017 0.1002
Schistosoma mansoni peptide (allatostatin)-like receptor 0.01 0.064 0.0639
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0005
Schistosoma mansoni sphingosine kinase A B 0.097 0.6801 0.6801
Brugia malayi AKH receptor 0.01 0.064 0.172
Trypanosoma cruzi Sphingosine kinase 0.0038 0.0198 0.781
Trypanosoma brucei diacylglycerol kinase, putative 0.0038 0.0198 0.781
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0118
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0122 0.0325
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.001 0.0008
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0.0003 0.0002
Schistosoma mansoni proteasome subunit alpha 6 (T01 family) 0.0038 0.0198 0.0197
Onchocerca volvulus Neuropeptide F receptor homolog 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0039 0.0212
Brugia malayi hypothetical protein 0.01 0.064 0.172
Schistosoma mansoni microtubule-associated protein tau 0.1422 1 1
Brugia malayi hypothetical protein 0.01 0.064 0.172
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.001 0.0008
Echinococcus multilocularis rhodopsin orphan GPCR 0.01 0.064 0.064
Echinococcus multilocularis smad 0.0024 0.0102 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0168 0.0986
Loa Loa (eye worm) MH1 domain-containing protein 0.0011 0.0007 0.0011
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0239 0.1624 0.1624
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0012 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0535 0.3718 0.5466
Schistosoma mansoni smad1 5 8 and 0.0024 0.0102 0.0101
Trypanosoma cruzi diacylglycerol kinase, putative 0.0038 0.0198 0.781
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0187 0.1102
Echinococcus multilocularis lamin 0.0027 0.0122 0.0122
Schistosoma mansoni coup transcription factor 0.0021 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0013 0.0023 0.0034
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0.0003 0.0002
Schistosoma mansoni hypothetical protein 0.01 0.064 0.0639
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.001 0.0003 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.01 0.064 0.064
Brugia malayi G protein-coupled receptor 0.01 0.064 0.172
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.008 0.0079
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0102 0.0102
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.01 0.064 0.0941
Loa Loa (eye worm) ceramide kinase 0.0038 0.0198 0.0291
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.01 0.064 0.064
Echinococcus multilocularis rhodopsin orphan GPCR 0.01 0.064 0.064
Schistosoma mansoni hypothetical protein 0.04 0.276 0.2759
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.008 0.008
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.008 0.008
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.008 0.0213
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Onchocerca volvulus 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Brugia malayi MH1 domain containing protein 0.0024 0.0102 0.0272
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.017 0.1002
Brugia malayi Dopamine receptor 0.01 0.064 0.172
Schistosoma mansoni hypothetical protein 0.0047 0.0261 0.026
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0154 0.0152
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0029
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.001 0.0003 0.0005
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.001 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.01 0.064 0.064
Onchocerca volvulus 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Echinococcus granulosus ceramide kinase 0.0038 0.0198 0.0198
Brugia malayi nuclear receptor NHR-88 0.0021 0.008 0.0213
Echinococcus multilocularis Smad4 0.0024 0.0102 0.0102
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0046 0.0253 1
Schistosoma mansoni diacylglycerol kinase zeta iota 0.0038 0.0198 0.0197
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.008 0.0213
Echinococcus multilocularis Diacylglycerol kinase zeta 0.0038 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.0026 0.0117 0.0173
Schistosoma mansoni lamin 0.0027 0.0122 0.0121
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0033 0.0162 0.6373
Brugia malayi hypothetical protein 0.01 0.064 0.172
Trichomonas vaginalis diacylglycerol kinase, putative 0.0038 0.0198 0.1168
Echinococcus multilocularis GPCR, family 2 0.0018 0.0055 0.0055
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.01 0.064 0.064
Trichomonas vaginalis diacylglycerol kinase, epsilon, putative 0.0038 0.0198 0.1168
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.001 0.001
Echinococcus granulosus expressed protein 0.001 0.0003 0.0003
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0239 0.1624 0.1624
Echinococcus granulosus smad 0.0024 0.0102 0.0102
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0122 0.0179
Brugia malayi sulfakinin receptor protein 0.01 0.064 0.172
Schistosoma mansoni smad1 5 8 and 0.0024 0.0102 0.0101
Echinococcus multilocularis neuropeptide s receptor 0.01 0.064 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0253 0.1497
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.008 0.0213
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.017 0.1002
Echinococcus granulosus 7TM GPCR rhodopsin 0.01 0.064 0.064
Echinococcus multilocularis g-protein coupled receptor 0.01 0.064 0.064
Schistosoma mansoni hypothetical protein 0.01 0.064 0.0639
Brugia malayi MH1 domain containing protein 0.0013 0.0026 0.0066
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Brugia malayi latrophilin 2 splice variant baaae 0.0038 0.0199 0.0533
Echinococcus granulosus mothers against decapentaplegic 2 0.0011 0.0007 0.0007
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.087 0.6094 0.6094
Onchocerca volvulus 0.01 0.064 0.172
Entamoeba histolytica diacylglycerol kinase, putative 0.0038 0.0198 0.0287
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0039 0.1438
Onchocerca volvulus Ceramide kinase 1 homolog 0.0038 0.0198 0.053
Echinococcus granulosus g protein coupled receptor 0.01 0.064 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0039 0.0212
Schistosoma mansoni lamin 0.0027 0.0122 0.0121
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.008 0.0079
Echinococcus granulosus peptide allatostatin:somatostatin 0.01 0.064 0.064
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0001 0.0002
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.001 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.008 0.0213
Onchocerca volvulus 0.01 0.064 0.172
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.008 0.0118
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0118
Onchocerca volvulus 0.01 0.064 0.172
Loa Loa (eye worm) neuropeptide F receptor 0.01 0.064 0.0941
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0129 0.019
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0055 0.0055
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0154 0.4835
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0046 0.0253 0.0252
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0187 0.1102
Brugia malayi diacylglycerol kinase 0.0038 0.0198 0.053
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0034 0.0168 0.0247
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0239 0.1624 0.1623
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.001 0.0003 0.0002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.008 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.01 0.064 0.064
Loa Loa (eye worm) runx1 0.0067 0.0406 0.0596
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.008 0.0079
Brugia malayi RNA recognition motif domain containing protein 0.0135 0.0888 0.2385
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.01 0.064 0.064
Echinococcus granulosus muscleblind protein 0.0155 0.1025 0.1025
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.01 0.064 0.172
Brugia malayi hypothetical protein 0.01 0.064 0.172
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0216 0.146 0.2147
Onchocerca volvulus 0.01 0.064 0.172
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0001 0.0001
Echinococcus granulosus rhodopsin orphan GPCR 0.01 0.064 0.064
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0888 0.0886
Loa Loa (eye worm) nuclear factor I 0.0013 0.0026 0.0038
Entamoeba histolytica hypothetical protein, conserved 0.097 0.6801 1
Echinococcus granulosus tm gpcr rhodopsin 0.01 0.064 0.064
Brugia malayi G-protein coupled receptor 0.01 0.064 0.172
Wolbachia endosymbiont of Brugia malayi parvulin-like peptidyl-prolyl isomerase, PPID 0.001 0.0003 0.5
Leishmania major diacylglycerol kinase, putative 0.0038 0.0198 0.781
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0039 0.0039
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0039 0.0101
Onchocerca volvulus 0.0021 0.008 0.0213
Schistosoma mansoni GTP-binding protein alpha subunit 0.001 0.0003 0.0002
Loa Loa (eye worm) DR-78 0.001 0.0001 0.0002
Echinococcus granulosus Diacylglycerol kinase zeta 0.0038 0.0198 0.0198
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.001 0.0003 0.0003
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0064 0.2469
Leishmania major sphingosine kinase A, B, putative 0.0038 0.0198 0.781
Schistosoma mansoni Smad4 0.0011 0.0007 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.017 0.1002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.008 0.008
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.001 0.0003 0.0005
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0046 0.0253 0.0253
Echinococcus granulosus Smad4 0.0024 0.0102 0.0102
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0023 0.0023
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0046 0.0253 0.0367
Toxoplasma gondii diacylglycerol kinase, putative 0.0038 0.0198 0.6259
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0014
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.008 0.0079
Echinococcus granulosus survival motor neuron protein 1 0.0229 0.1552 0.1552
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0102 0.0151
Brugia malayi gonadotropin-releasing hormone receptor 2 0.01 0.064 0.172
Loa Loa (eye worm) melatonin receptor type 1A 0.01 0.064 0.0941
Brugia malayi Ceramide kinase 0.0038 0.0198 0.053
Onchocerca volvulus 0.005 0.0285 0.0764
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0054
Schistosoma mansoni neuropeptide receptor 0.01 0.064 0.0639
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus multilocularis neuropeptide receptor 0.01 0.064 0.064
Echinococcus granulosus acylglycerol kinase mitochondrial 0.0038 0.0198 0.0198
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0033 0.0049
Echinococcus granulosus intermediate filament protein 0.0027 0.0122 0.0122
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0033 0.0162 0.6373
Schistosoma mansoni histamine h1 receptor 0.01 0.064 0.0639
Echinococcus granulosus GPCR family 2 0.0018 0.0055 0.0055
Onchocerca volvulus 0.0038 0.0198 0.053
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0038 0.0198 0.1168
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Toxoplasma gondii diacylglycerol kinase accessory domain (presumed) domain-containing protein 0.0038 0.0198 0.6259
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.008 0.0079
Entamoeba histolytica diacylglycerol kinase, putative 0.0038 0.0198 0.0287
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0001 0.0001
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.008 0.0213
Brugia malayi TAR-binding protein 0.0135 0.0888 0.2385
Echinococcus granulosus guanine nucleotide binding protein G protein 0.001 0.0003 0.0003
Schistosoma mansoni neuropeptide F-like receptor 0.01 0.064 0.0639
Brugia malayi putative neuropeptide receptor NPR1 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.0013 0.0026 0.0038
Echinococcus multilocularis neuropeptides capa receptor 0.01 0.064 0.064
Schistosoma mansoni cpg binding protein 0.0028 0.0129 0.0128
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.008 0.0118
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.001 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0056 0.0324 0.0476
Echinococcus multilocularis rhodopsin orphan GPCR 0.01 0.064 0.064
Brugia malayi MH2 domain containing protein 0.0011 0.0007 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0121 0.0708
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0014
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0102 0.0102
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0039 0.0212
Schistosoma mansoni diacylglycerol kinase theta 0.0038 0.0198 0.0197
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.01 0.064 0.0639
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0039 0.1438
Schistosoma mansoni Smad4 0.0011 0.0007 0.0006
Onchocerca volvulus 0.0027 0.0122 0.0325
Echinococcus multilocularis alpha 1A adrenergic receptor 0.01 0.064 0.064
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.01 0.064 0.064
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0034 0.0168 0.0448
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus granulosus g protein coupled receptor 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Echinococcus multilocularis survival motor neuron protein 1 0.0229 0.1552 0.1552
Onchocerca volvulus 0.0246 0.1671 0.4493
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0102 0.0151
Echinococcus granulosus g protein coupled receptor 0.01 0.064 0.064
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.01 0.064 0.172
Echinococcus multilocularis muscleblind protein 1 0.0155 0.1025 0.1025
Trichomonas vaginalis sphingosine kinase, putative 0.0038 0.0198 0.1168
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.001 0.0003 0.0002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.01 0.064 0.0639
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.01 0.064 0.0639
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni hypothetical protein 0.0012 0.0014 0.0013
Echinococcus multilocularis rhodopsin orphan GPCR 0.01 0.064 0.064
Schistosoma mansoni lozenge 0.0067 0.0406 0.0404
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.008 0.0213
Loa Loa (eye worm) hypothetical protein 0.097 0.6801 1
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0055 0.0145
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.001 0.0003 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0123 0.0719
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0046 0.0253 1
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Onchocerca volvulus 0.001 0.0003 0.0005
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.01 0.064 0.0639
Schistosoma mansoni hypothetical protein 0.01 0.064 0.0639
Brugia malayi hypothetical protein 0.01 0.064 0.172
Leishmania major hypothetical protein, conserved 0.0038 0.0198 0.781
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.001 0.0003 0.0003
Trypanosoma cruzi diacylglycerol kinase-like protein, putative 0.0038 0.0198 0.781
Echinococcus multilocularis somatostatin receptor 0.01 0.064 0.064
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0039 0.1438
Onchocerca volvulus 0.0535 0.3718 1
Onchocerca volvulus 0.01 0.064 0.172
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.01 0.064 0.0941
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.0187 0.7375
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0046 0.0253 1
Leishmania major hypothetical protein, conserved 0.0038 0.0198 0.781
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0118
Toxoplasma gondii diacylglycerol kinase catalytic domain-containing protein 0.0038 0.0198 0.6259
Brugia malayi hypothetical protein 0.001 0.0003 0.0005
Echinococcus granulosus orexin receptor type 2 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0027 0.0119 0.0174
Loa Loa (eye worm) follicle stimulating hormone receptor 0.01 0.064 0.0941
Onchocerca volvulus 0.001 0.0003 0.0005
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.01 0.064 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0105 0.0608
Schistosoma mansoni hypothetical protein 0.0728 0.5086 0.5085
Schistosoma mansoni amine GPCR 0.01 0.064 0.0639
Echinococcus granulosus dro:myosuppressin receptor 0.01 0.064 0.064
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0046 0.0253 1
Schistosoma mansoni neuropeptide receptor 0.01 0.064 0.0639
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.003 0.0141 0.0141
Loa Loa (eye worm) MH2 domain-containing protein 0.0011 0.0007 0.0011
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.0187 0.7375
Onchocerca volvulus 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0118
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0118
Loa Loa (eye worm) hypothetical protein 0.0535 0.3718 0.5466
Echinococcus granulosus alpha 1A adrenergic receptor 0.01 0.064 0.064
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0055 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.01 0.064 0.064
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0888 0.0886
Leishmania major hypothetical protein, conserved 0.0026 0.0117 0.4588
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0291
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.008 0.008
Schistosoma mansoni hypothetical protein 0.0018 0.0055 0.0054
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Echinococcus granulosus rhodopsin orphan GPCR 0.01 0.064 0.064
Echinococcus multilocularis microtubule associated protein 2 0.1422 1 1
Loa Loa (eye worm) neuropeptide F receptor 0.01 0.064 0.0941
Schistosoma mansoni survival motor neuron protein 0.0047 0.0261 0.026
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.001 0.0003 0.0003
Plasmodium falciparum diacylglycerol kinase, putative 0.0038 0.0198 1
Echinococcus multilocularis orexin receptor type 2 0.01 0.064 0.064
Brugia malayi Serotonin/octopamine receptor family protein 7 0.01 0.064 0.172
Onchocerca volvulus 0.0032 0.0154 0.041
Brugia malayi G protein-coupled receptor F59B2.13 0.01 0.064 0.172
Brugia malayi RE15519p 0.01 0.064 0.172
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.0187 0.7375
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0324 0.0476
Schistosoma mansoni biogenic amine (5HT) receptor 0.01 0.064 0.0639
Echinococcus multilocularis rhodopsin orphan GPCR 0.01 0.064 0.064
Loa Loa (eye worm) eye-specific diacylglycerol kinase 0.0038 0.0198 0.0291
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.001 0.0003 0.0005
Echinococcus multilocularis neuropeptides capa receptor 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Brugia malayi Pre-SET motif family protein 0.0032 0.0154 0.041
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.0187 0.1102
Onchocerca volvulus 0.001 0.0003 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0154 0.0152
Echinococcus granulosus neuropeptide Y receptor 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0033 0.0086
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.008 0.0213
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0118
Loa Loa (eye worm) hypothetical protein 0.005 0.0285 0.042
Echinococcus multilocularis expressed protein 0.0034 0.0168 0.0168
Echinococcus granulosus tachykinin peptides receptor 99D 0.01 0.064 0.064
Brugia malayi ORL1-like opioid receptor 0.01 0.064 0.172
Schistosoma mansoni thyroid hormone receptor 0.0021 0.008 0.0079
Echinococcus multilocularis G-protein coupled receptor, putative 0.01 0.064 0.064
Schistosoma mansoni biogenic amine receptor 0.01 0.064 0.0639
Echinococcus multilocularis g protein coupled receptor 0.01 0.064 0.064
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.001 0.0003 0.0005
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni biogenic amine (dopamine) receptor 0.01 0.064 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.017 0.1002
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.008 0.008
Schistosoma mansoni amine GPCR 0.01 0.064 0.0639
Loa Loa (eye worm) hypothetical protein 0.0155 0.1025 0.1508
Echinococcus multilocularis neuropeptide receptor A26 0.01 0.064 0.064
Echinococcus granulosus mothers against decapentaplegic 6 0.0011 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.01 0.064 0.0941
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.008 0.0213
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Schistosoma mansoni opsin-like receptor 0.01 0.064 0.0639
Schistosoma mansoni neuropeptide receptor 0.01 0.064 0.0639
Echinococcus granulosus allatostatin A receptor 0.01 0.064 0.064
Loa Loa (eye worm) phosphatidylinositol 3 0.0046 0.0253 0.0372
Echinococcus multilocularis biogenic amine (5HT) receptor 0.01 0.064 0.064
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0001 0.0001
Echinococcus granulosus neuropeptides capa receptor 0.01 0.064 0.064
Schistosoma mansoni neuropeptide F-like receptor 0.01 0.064 0.0639
Brugia malayi Pre-SET motif family protein 0.0216 0.146 0.3925
Schistosoma mansoni cpg binding protein 0.003 0.014 0.0139
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0001 0.0001
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0105 0.0608
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0239 0.1624 0.1624
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0117 0.4588
Brugia malayi RNA binding protein 0.0135 0.0888 0.2385
Echinococcus multilocularis neuropeptide FF receptor 2 0.01 0.064 0.064
Echinococcus granulosus cpg binding protein 0.003 0.014 0.014
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0029
Schistosoma mansoni tar DNA-binding protein 0.0135 0.0888 0.0886
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.001 0.0003 0.0002
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.008 0.0118
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0005
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.001 0.0003 0.0002
Giardia lamblia GTOR 0.0046 0.0253 0.5
Echinococcus granulosus sphingosine kinase 1 0.097 0.6801 0.6801
Plasmodium vivax diacylglycerol kinase, putative 0.0038 0.0198 1
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0198 0.781
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Trypanosoma brucei Diacylglycerol kinase catalytic domain containing protein, putative 0.0038 0.0198 0.781
Schistosoma mansoni growth hormone secretagogue receptor 0.01 0.064 0.0639
Loa Loa (eye worm) TAR-binding protein 0.0135 0.0888 0.1305
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0046 0.0253 0.0677
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.008 0.0118
Schistosoma mansoni smad1 5 8 and 0.0024 0.0102 0.0101
Echinococcus multilocularis g protein coupled receptor 0.01 0.064 0.064
Schistosoma mansoni amine GPCR 0.01 0.064 0.0639
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0033 0.0162 0.6373
Brugia malayi nuclear receptor RXR 0.0011 0.001 0.0023
Trypanosoma cruzi diacylglycerol kinase, putative 0.0038 0.0198 0.781
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0055 0.0055
Echinococcus granulosus rhodopsin orphan GPCR 0.01 0.064 0.064
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0039 0.1438
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.008 0.0213
Loa Loa (eye worm) MH2 domain-containing protein 0.0356 0.2454 0.3608
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0121 0.0708
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.008 0.0213
Echinococcus granulosus serotonin receptor 0.01 0.064 0.064
Echinococcus granulosus lamin dm0 0.0027 0.0122 0.0122
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.001 0.0003 0.0003
Schistosoma mansoni biogenic amine (5HT) receptor 0.01 0.064 0.0639
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0135 0.0888 0.1305
Schistosoma mansoni rhodopsin-like orphan GPCR 0.01 0.064 0.0639
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0102 0.0102
Loa Loa (eye worm) RNA binding protein 0.0135 0.0888 0.1305
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.008 0.008
Echinococcus granulosus tm gpcr rhodopsin 0.01 0.064 0.064
Echinococcus granulosus sex peptide receptor 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0014
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.01 0.064 0.064
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.008 0.008
Brugia malayi Serotonin receptor 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Onchocerca volvulus 0.01 0.064 0.172
Echinococcus granulosus neuropeptide FF receptor 2 0.01 0.064 0.064
Brugia malayi hypothetical protein 0.01 0.064 0.172
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.008 0.0213
Loa Loa (eye worm) G-protein coupled receptor 0.01 0.064 0.0941
Echinococcus granulosus neuropeptides capa receptor 0.01 0.064 0.064
Loa Loa (eye worm) Smad1 0.0024 0.0102 0.0151
Echinococcus multilocularis dnaJ subfamily B 0.04 0.276 0.276
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0039 0.0037
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.0206 0.1214
Schistosoma mansoni neuropeptide f receptor 76f 0.01 0.064 0.0639
Brugia malayi Smad1 0.0024 0.0102 0.0272
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.008 0.0213
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.01 0.064 0.064
Brugia malayi Dopamine receptor protein 2 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Brugia malayi G-protein coupled receptor 0.01 0.064 0.172
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0001 0.0002
Schistosoma mansoni alpha-1 adrenergic receptor 0.01 0.064 0.0639
Brugia malayi MH2 domain containing protein 0.0024 0.0102 0.0272
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0039 0.0039
Toxoplasma gondii peptidylprolyl isomerase 0.0033 0.0162 0.5108
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.008 0.0079
Mycobacterium tuberculosis Conserved protein 0.097 0.6801 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0005
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.017 0.5369
Onchocerca volvulus 0.01 0.064 0.172
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0239 0.1624 0.1623
Brugia malayi neuropeptide F receptor 0.01 0.064 0.172
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0239 0.1624 0.1624
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0001 0.0001
Brugia malayi putative neuropeptide receptor 0.01 0.064 0.172
Loa Loa (eye worm) TYRA-2 protein 0.01 0.064 0.0941
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0239 0.1624 0.4367
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.001 0.0003 0.0005
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0022 0.0083 0.321
Echinococcus multilocularis g protein coupled receptor 0.01 0.064 0.064
Echinococcus multilocularis ceramide kinase 0.0038 0.0198 0.0198
Echinococcus multilocularis cpg binding protein 0.003 0.014 0.014
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.01 0.064 0.0639
Echinococcus multilocularis musashi 0.0027 0.0122 0.0122
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.01 0.064 0.0639
Echinococcus granulosus tumor protein p63 0.0342 0.2355 0.2355
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0154 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.008 0.0213
Brugia malayi hypothetical protein 0.01 0.064 0.172
Echinococcus multilocularis fmrfamide receptor 0.01 0.064 0.064
Echinococcus multilocularis lamin dm0 0.0027 0.0122 0.0122
Brugia malayi GnHR receptor homolog 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Brugia malayi hypothetical protein 0.01 0.064 0.172
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.001 0.0003 0.0005
Echinococcus multilocularis neuropeptide receptor 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.0038 0.0198 0.0291
Plasmodium falciparum diacylglycerol kinase, putative 0.0038 0.0198 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Brugia malayi hypothetical protein 0.0011 0.001 0.0023
Schistosoma mansoni biogenic amine receptor 0.01 0.064 0.0639
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.0104 0.0606
Schistosoma mansoni nuclear hormone receptor 0.0021 0.008 0.0079
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0001 0.0002
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.017 0.1002
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Trypanosoma cruzi Sphingosine kinase 0.0038 0.0198 0.781
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.008 0.0079
Loa Loa (eye worm) hypothetical protein 0.0021 0.008 0.0118
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0261 0.07
Trichomonas vaginalis diacylglycerol kinase, zeta, iota, putative 0.0038 0.0198 0.1168
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Schistosoma mansoni hypothetical protein 0.0038 0.0199 0.0198
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.008 0.0213
Brugia malayi larval opioid receptor 0.01 0.064 0.172
Loa Loa (eye worm) hypothetical protein 0.0018 0.0055 0.0081
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.008 0.0118
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0039 0.0212
Brugia malayi Melatonin receptor type 1A 0.01 0.064 0.172
Schistosoma mansoni Smad4 0.0024 0.0102 0.0101
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.001 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.001 0.0001 0.0002
Echinococcus granulosus neuropeptide receptor A26 0.01 0.064 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0012 0.0017 0.0083
Brugia malayi CXXC zinc finger family protein 0.0028 0.0129 0.0344
Schistosoma mansoni rotamase 0.0034 0.0168 0.0167
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.008 0.008
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.008 0.0213
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.008 0.0118
Echinococcus multilocularis rhodopsin orphan GPCR 0.01 0.064 0.064
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.01 0.064 0.064
Onchocerca volvulus 0.01 0.064 0.172
Echinococcus granulosus rhodopsin orphan GPCR 0.01 0.064 0.064
Echinococcus granulosus 7tm_1 domain containing protein 0.01 0.064 0.064
Loa Loa (eye worm) hypothetical protein 0.001 0.0003 0.0005
Echinococcus granulosus somatostatin receptor 0.01 0.064 0.064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0046 0.0253 0.1497
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0324 0.0868
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0039 0.0212
Loa Loa (eye worm) hypothetical protein 0.01 0.064 0.0941
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0122 0.0179
Echinococcus multilocularis serotonin receptor 0.01 0.064 0.064
Schistosoma mansoni trimeric G-protein alpha o subunit 0.001 0.0003 0.0002
Loa Loa (eye worm) G-protein coupled receptor 0.01 0.064 0.0941
Echinococcus granulosus expressed protein 0.0034 0.0168 0.0168
Brugia malayi MH2 domain containing protein 0.0356 0.2454 0.6599
Echinococcus multilocularis G protein coupled receptor 139 0.01 0.064 0.064
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.0011 0.001 0.0014

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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