Detailed information for compound 568102

Basic information

Technical information
  • TDR Targets ID: 568102
  • Name: 8-methyl-8-azabicyclo[3.2.1]octan-3-one hydro bromide
  • MW: 220.107 | Formula: C8H14BrNO
  • H donors: 0 H acceptors: 1 LogP: 1.31 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN1C2CCC1CC(=O)C2.Br
  • InChi: 1S/C8H13NO.BrH/c1-9-6-2-3-7(9)5-8(10)4-6;/h6-7H,2-5H2,1H3;1H
  • InChiKey: NFIYUASUOPYSJQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1alpha-4,5alpha-4-Tropan-3-one, hydrobromide
  • 8-Azabicyclo(3.2.1)octan-3-one, 8-methyl-, hydrobromide (9CI)
  • NSC 83230
  • ST5443831
  • 1-alpha-H,5-alpha-H-Tropan-3-one, hydrobromide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0031 0.0245 0.0518
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0012 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0045 0.0077
Leishmania major mitochondrial DNA polymerase beta 0.0303 0.3626 1
Schistosoma mansoni hypothetical protein 0.0364 0.4386 0.928
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0061 0.062 0.3347
Schistosoma mansoni hypothetical protein 0.0075 0.0794 0.1679
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0031 0.0245 0.1792
Schistosoma mansoni retinoic acid receptor RXR 0.0031 0.0245 0.0518
Trichomonas vaginalis Phospholipase C precursor, putative 0.0012 0.0017 0.0231
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0391 0.4726 0.741
Schistosoma mansoni carbon catabolite repressor protein 0.0012 0.0017 0.0036
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0012 0.0017 0.0039
Echinococcus granulosus cpg binding protein 0.0031 0.0244 0.0383
Schistosoma mansoni nuclear receptor nhr-48 0.0014 0.0044 0.0093
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0017 0.0074 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0031 0.0245 0.0416
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0073 0.0154
Onchocerca volvulus 0.0027 0.0202 0.1472
Brugia malayi steroid hormone receptor 0.0031 0.0245 0.0416
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0017 0.0074 0.0074
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0017 0.0231
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0391 0.4726 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0303 0.3626 1
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0016 0.0066 0.0103
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.004 0.0366 0.0574
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0012 0.0017 0.0039
Onchocerca volvulus Huntingtin homolog 0.012 0.1354 1
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0031 0.0245 0.0384
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0017 0.0074 0.0125
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0035 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.0025 0.0179 0.0304
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0031 0.0245 0.0416
Loa Loa (eye worm) hypothetical protein 0.0017 0.0073 0.0123
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0012 0.0017 0.0017
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0665 0.1406
Entamoeba histolytica hypothetical protein 0.004 0.0366 0.5883
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0005
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0111
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0025 0.0179 0.0487
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0031 0.0245 0.0384
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0111
Loa Loa (eye worm) hypothetical protein 0.0031 0.0245 0.0416
Brugia malayi jmjC domain containing protein 0.0017 0.0073 0.0123
Loa Loa (eye worm) hypothetical protein 0.0025 0.0179 0.0304
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0143 0.1645 0.4532
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0005
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0073 0.0114
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0031 0.0245 0.0518
Mycobacterium ulcerans hypothetical protein 0.016 0.1846 1
Echinococcus multilocularis transcription factor btf3 0.004 0.0356 0.0356
Onchocerca volvulus Bile acid receptor homolog 0.0031 0.0245 0.1792
Onchocerca volvulus Putative neutral sphingomyelinase 0.0012 0.0017 0.0105
Brugia malayi hypothetical protein 0.0017 0.0074 0.0125
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0245 0.0416
Loa Loa (eye worm) ICD-1 protein 0.004 0.0356 0.0604
Onchocerca volvulus Protein ultraspiracle homolog 0.0031 0.0245 0.1792
Entamoeba histolytica hypothetical protein 0.0025 0.0179 0.2858
Schistosoma mansoni cpg binding protein 0.0029 0.0224 0.0473
Loa Loa (eye worm) hypothetical protein 0.0017 0.0073 0.0123
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0044 0.0305
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0012 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0111
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0245 0.0245
Echinococcus multilocularis nibrin 0.0011 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0125
Echinococcus granulosus neuropeptide s receptor 0.0524 0.6379 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0064 0.0665 0.1128
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0036
Entamoeba histolytica hypothetical protein 0.004 0.0366 0.5883
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0012 0.0017 0.0027
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0391 0.4726 0.4726
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0031 0.0245 0.0416
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0012 0.0017 0.0036
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0017 0.0029
Brugia malayi jmjC domain containing protein 0.0017 0.0073 0.0123
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0224 0.038
Echinococcus multilocularis expressed protein 0.0017 0.0074 0.0074
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0394 0.1078
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0073 0.0123
Brugia malayi hypothetical protein 0.0016 0.0066 0.0111
Schistosoma mansoni nocturnin 0.0012 0.0017 0.0036
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0044 0.0093
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0017 0.0039
Treponema pallidum exodeoxyribonuclease (exoA) 0.0061 0.062 1
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0012 0.0017 0.0231
Loa Loa (eye worm) nuclear receptor NHR-67 0.0014 0.0044 0.0075
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0093 0.0093
Entamoeba histolytica transcription factor BTF3, putative 0.004 0.0356 0.5716
Brugia malayi Calcitonin receptor-like protein seb-1 0.0109 0.1223 0.2077
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0073 0.0073
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0245 0.0416
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0017 0.0074 0.1145
Plasmodium vivax sphingomyelin synthase 2, putative 0.0025 0.0179 0.2858
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0061 0.062 0.1703
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.0356 0.0973
Onchocerca volvulus 0.0031 0.0245 0.1792
Echinococcus granulosus neuropeptide receptor A26 0.0524 0.6379 1
Echinococcus granulosus transcription factor btf3 0.004 0.0356 0.0557
Schistosoma mansoni hypothetical protein 0.004 0.0366 0.0774
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0044 0.0069
Trypanosoma brucei transcription factor BTF3, putative 0.004 0.0356 0.0973
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.004 0.0366 0.0366
Schistosoma mansoni GTP-binding protein alpha subunit 0.0017 0.0074 0.0156
Plasmodium vivax exodeoxyribonuclease III, putative 0.0012 0.0017 0.0231
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0017 0.0074 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0031 0.0245 0.0416
Treponema pallidum hypothetical protein 0.0012 0.0017 0.0231
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0073 0.0192
Echinococcus multilocularis tumor protein p63 0.0331 0.3972 0.3972
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0017 0.0074 0.0156
Plasmodium falciparum basic transcription factor 3b, putative 0.004 0.0356 0.5716
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0031 0.0245 0.0518
Schistosoma mansoni DNA ligase IV 0.0011 0.0003 0.0006
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0061 0.062 0.1703
Echinococcus granulosus muscleblind protein 0.0148 0.1702 0.2668
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0003 0.0000056329
Loa Loa (eye worm) hypothetical protein 0.012 0.1354 0.2298
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0005
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0012 0.0017 0.0039
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0017 0.0039
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0391 0.4726 0.4726
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0017 0.0074 0.0156
Echinococcus multilocularis lamin dm0 0.0027 0.0202 0.0202
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0012 0.0017 0.0029
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0014 0.0044 0.0305
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0016 0.0066 0.0139
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0029
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Brugia malayi hypothetical protein 0.004 0.0366 0.0621
Echinococcus multilocularis muscleblind protein 1 0.0148 0.1702 0.1702
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0073 0.1129
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0012 0.0017 0.0231
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0017 0.0039
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0073 0.0114
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0005
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0061 0.062 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0061 0.062 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0031 0.0245 0.0416
Entamoeba histolytica hypothetical protein 0.004 0.0366 0.5883
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0061 0.062 0.0972
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0017 0.0074 0.0115
Brugia malayi Nuclear hormone receptor-like 1 0.0031 0.0245 0.0416
Brugia malayi jmjC domain containing protein 0.0064 0.0665 0.1128
Loa Loa (eye worm) fli-1 protein 0.0228 0.2696 0.4576
Entamoeba histolytica hypothetical protein 0.004 0.0356 0.5716
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0017 0.0074 0.0115
Brugia malayi nuclear hormone receptor 0.0031 0.0245 0.0416
Schistosoma mansoni synaptojanin 0.0012 0.0017 0.0036
Schistosoma mansoni cript-related 0.0012 0.0017 0.0036
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Echinococcus multilocularis cpg binding protein 0.0031 0.0244 0.0244
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0017 0.0231
Onchocerca volvulus 0.0017 0.0074 0.0523
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0093 0.0146
Brugia malayi nuclear hormone receptor family member nhr-6 0.0014 0.0044 0.0075
Entamoeba histolytica hypothetical protein 0.0025 0.0179 0.2858
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0017 0.0074 0.1145
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0017 0.0074 0.0115
Brugia malayi nuclear receptor NHR-67 0.0014 0.0044 0.0075
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0017 0.0074 0.0125
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0143 0.0243
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0012 0.0017 0.0017
Onchocerca volvulus 0.0012 0.0017 0.0105
Loa Loa (eye worm) hypothetical protein 0.0027 0.0196 0.0332
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0626 0.1325
Loa Loa (eye worm) hypothetical protein 0.0075 0.0794 0.1347
Brugia malayi ecdysone receptor 0.0014 0.0044 0.0075
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0017 0.0074 0.0156
Echinococcus granulosus GPCR family 2 0.0035 0.0295 0.0462
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0125
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0073 0.0073
Leishmania major hypothetical protein, conserved 0.0017 0.0073 0.0153
Plasmodium vivax JmjC domain containing protein 0.0017 0.0073 0.1129
Echinococcus granulosus tumor protein p63 0.0331 0.3972 0.6226
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0017 0.0074 0.0125
Echinococcus multilocularis lamin 0.0027 0.0202 0.0202
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0025 0.0179 0.0487
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0017 0.0074 0.0156
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0644 0.0644
Giardia lamblia Inositol 5-phosphatase 4 0.0012 0.0017 0.0231
Echinococcus granulosus phd:f box containing protein 0.0017 0.0073 0.0114
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0394 0.1078
Echinococcus granulosus nuclear receptor nhr 48 0.0014 0.0044 0.0069
Schistosoma mansoni nuclear hormone receptor 0.0031 0.0245 0.0518
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0356 0.5716
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0012 0.0017 0.0039
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0012 0.0017 0.0231
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0111
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0017 0.0074 0.0156
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0027 0.0027
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0017 0.0074 0.0125
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0025 0.0179 0.2858
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0061 0.062 1
Entamoeba histolytica G protein alpha subunit, putative 0.0017 0.0074 0.1145
Schistosoma mansoni chromosome transmission fidelity factor 0.0011 0.0003 0.0006
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0017 0.0074 0.0125
Trypanosoma cruzi mitochondrial protein 99, putative 0.0012 0.0017 0.0039
Brugia malayi G-protein alpha subunit 0.0017 0.0074 0.0125
Trypanosoma cruzi sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0025 0.0179 0.0487
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0394 0.1078
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0012 0.0017 0.0039
Brugia malayi Latrophilin receptor protein 2 0.0035 0.0295 0.05
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0017 0.0074 0.1145
Toxoplasma gondii ATPase, AAA family protein 0.0011 0.0003 0.0000056329
Mycobacterium tuberculosis Conserved hypothetical protein 0.016 0.1846 1
Schistosoma mansoni hypothetical protein 0.0035 0.0295 0.0623
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.0356 0.0973
Loa Loa (eye worm) G protein alpha subunit 3 0.0017 0.0074 0.0125
Schistosoma mansoni nuclear hormone receptor 0.0014 0.0044 0.0093
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0017 0.0231
Echinococcus granulosus synaptojanin 1 0.0012 0.0017 0.0027
Echinococcus granulosus geminin 0.0364 0.4386 0.6876
Schistosoma mansoni nuclear receptor 0.0014 0.0044 0.0093
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0017 0.0074 0.0125
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 3 0.0025 0.0179 0.0304
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0073 0.0073
Brugia malayi nuclear hormone receptor family member odr-7 0.0014 0.0044 0.0075
Echinococcus granulosus GA binding protein alpha chain 0.0075 0.0797 0.125
Echinococcus multilocularis traf and tnf receptor associated protein 0.0012 0.0017 0.0017
Schistosoma mansoni lamin 0.0027 0.0202 0.0427
Brugia malayi hypothetical protein 0.0016 0.0066 0.0111
Brugia malayi follicle stimulating hormone receptor 0.0269 0.3205 0.5441
Plasmodium falciparum sphingomyelin synthase 1, putative 0.0025 0.0179 0.2858
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0011 0.0003 0.0000056329
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0017 0.0074 0.0125
Echinococcus granulosus lysine specific demethylase 5A 0.0064 0.0665 0.1042
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0012 0.0017 0.0039
Echinococcus granulosus sphingomyelin synthase protein 1 0.0025 0.0179 0.0281
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0017 0.0074 0.1145
Giardia lamblia hypothetical protein 0.0012 0.0017 0.0231
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0202 0.0343
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0109 0.1223 0.2077
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0644 0.1363
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0073 0.0192
Loa Loa (eye worm) hypothetical protein 0.0025 0.0179 0.0304
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0025 0.0179 0.0304
Schistosoma mansoni hypothetical protein 0.0012 0.0017 0.0036
Brugia malayi hypothetical protein 0.0014 0.0044 0.0075
Trichomonas vaginalis hypothetical protein 0.0025 0.0179 0.2858
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0061 0.062 0.167
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Toxoplasma gondii exonuclease III APE 0.0061 0.062 1
Loa Loa (eye worm) steroid hormone receptor 0.0031 0.0245 0.0416
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0073 0.0073
Echinococcus multilocularis geminin 0.0364 0.4386 0.4386
Schistosoma mansoni synaptojanin 0.0012 0.0017 0.0036
Loa Loa (eye worm) hypothetical protein 0.0017 0.0073 0.0123
Loa Loa (eye worm) hypothetical protein 0.0031 0.0245 0.0416
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0031 0.0245 0.0416
Leishmania major basic transcription factor 3a, putative 0.004 0.0356 0.0938
Chlamydia trachomatis DNA ligase 0.0011 0.0003 0.5
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0025 0.0179 0.2858
Echinococcus multilocularis sphingomyelin synthase protein 1 0.0025 0.0179 0.0179
Loa Loa (eye worm) DR-78 0.0014 0.0044 0.0075
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Echinococcus granulosus Nuclear hormone receptor HR96 0.0014 0.0044 0.0069
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0073 0.1129
Echinococcus multilocularis synaptojanin 1 0.0012 0.0017 0.0017
Brugia malayi Steroid receptor seven-up type 2 0.0031 0.0245 0.0416
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0017 0.0231
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0031 0.0245 0.0416
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0148 0.1702 0.2889
Schistosoma mansoni neutral sphingomyelinase 0.0012 0.0017 0.0036
Echinococcus granulosus traf and tnf receptor associated protein 0.0012 0.0017 0.0027
Brugia malayi hypothetical protein 0.0014 0.0044 0.0075
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0029
Onchocerca volvulus 0.0048 0.0466 0.3427
Echinococcus multilocularis musashi 0.0027 0.0202 0.0202
Echinococcus multilocularis thyroid hormone receptor alpha 0.0031 0.0245 0.0245
Schistosoma mansoni ets-related 0.0228 0.2696 0.5704
Brugia malayi topoisomerase 0.0011 0.0003 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0031 0.0245 0.0416
Echinococcus granulosus FTZ F1 alpha 0.0031 0.0245 0.0384
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0031 0.0245 0.0384
Brugia malayi CCR4 0.0012 0.0017 0.0029
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0035 0.0295 0.0295
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0644 0.0644
Schistosoma mansoni ap endonuclease 0.0061 0.062 0.1311
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0014 0.0044 0.0075
Echinococcus multilocularis neutral sphingomyelinase 0.0012 0.0017 0.0017
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0012 0.0017 0.0231
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0073 0.0123
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0014 0.0044 0.0044
Entamoeba histolytica hypothetical membrane-spanning protein 0.0025 0.0179 0.2858
Echinococcus granulosus thyroid hormone receptor alpha 0.0014 0.0044 0.0069
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0016 0.0066 0.0111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0031 0.0245 0.0416
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0031 0.0245 0.0416
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0031 0.0245 0.0245
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0017 0.0074 0.0074
Echinococcus multilocularis ecdysone induced protein 78C 0.0031 0.0245 0.0245
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0025 0.0179 0.2858
Echinococcus multilocularis neuropeptide s receptor 0.0524 0.6379 0.6379
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0014 0.0044 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0031 0.0245 0.0416
Brugia malayi photoreceptor-specific nuclear receptor 0.0031 0.0245 0.0416
Loa Loa (eye worm) hypothetical protein 0.0048 0.0466 0.0791
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0017 0.0074 0.0156
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0391 0.4726 0.8023
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0044 0.0044
Schistosoma mansoni cpg binding protein 0.0031 0.0244 0.0517
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0061 0.062 0.3295
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0036
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0017 0.0074 0.0115
Onchocerca volvulus 0.0017 0.0074 0.0523
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0031 0.0245 0.0416
Loa Loa (eye worm) hypothetical protein 0.0016 0.0066 0.0111
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0061 0.062 0.1052
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0044 0.0075
Schistosoma mansoni topbp1 0.0011 0.0003 0.0006
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0245 0.0416
Loa Loa (eye worm) hypothetical protein 0.0031 0.0245 0.0416
Entamoeba histolytica hypothetical protein 0.0025 0.0179 0.2858
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0031 0.0245 0.0416
Toxoplasma gondii hypothetical protein 0.0049 0.0471 0.7594
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0014 0.0044 0.0093
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0017 0.0029
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.1645 0.451
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0466 0.0986
Loa Loa (eye worm) hypothetical protein 0.0031 0.0245 0.0416
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0391 0.4726 1
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0011 0.0003 0.0000056329
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0245 0.0518
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0027 0.0043
Trichomonas vaginalis replication factor C large subunit, putative 0.0011 0.0003 0.0000056329
Brugia malayi Ets-domain containing protein 0.0075 0.0797 0.1353
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0031 0.0245 0.0384
Echinococcus granulosus replication factor c subunit 1 0.0011 0.0003 0.0005
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0073 0.0154
Loa Loa (eye worm) hypothetical protein 0.0148 0.1702 0.2889
Onchocerca volvulus 0.0017 0.0074 0.0523
Loa Loa (eye worm) hypothetical protein 0.0031 0.0245 0.0416
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0005
Brugia malayi beta-NAC-like protein 0.004 0.0356 0.0604
Plasmodium falciparum DNase I-like protein, putative 0.0012 0.0017 0.0231
Brugia malayi hypothetical protein 0.0011 0.0003 0.0005
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Echinococcus multilocularis replication factor c subunit 1 0.0011 0.0003 0.0003
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0109 0.1223 0.2077
Brugia malayi conserved hypotetical protein 0.0014 0.0044 0.0075
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0017 0.0074 0.0074
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Loa Loa (eye worm) latrophilin receptor protein 2 0.0035 0.0295 0.05
Onchocerca volvulus 0.0014 0.0044 0.0305
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0012 0.0017 0.0231
Loa Loa (eye worm) hypothetical protein 0.0064 0.0662 0.1124
Brugia malayi nuclear hormone receptor 0.0014 0.0044 0.0075
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0202 0.0343
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0017 0.0039
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0017 0.0074 0.0125
Brugia malayi ecdysteroid receptor 0.0031 0.0245 0.0416
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0391 0.4726 0.8023
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Loa Loa (eye worm) hypothetical protein 0.0035 0.0295 0.05
Echinococcus granulosus lamin 0.0027 0.0202 0.0316
Loa Loa (eye worm) hypothetical protein 0.0025 0.0179 0.0304
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0014 0.0044 0.0044
Schistosoma mansoni steroid hormone receptor ad4bp 0.0031 0.0245 0.0518
Brugia malayi Muscleblind-like protein 0.0148 0.1702 0.2889
Brugia malayi exodeoxyribonuclease III family protein 0.0061 0.062 0.1052
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0143 0.1645 0.4532
Schistosoma mansoni coup transcription factor 0.0031 0.0245 0.0518
Brugia malayi Ets-domain containing protein 0.0075 0.0797 0.1353
Schistosoma mansoni zinc finger protein 0.0014 0.0044 0.0093
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0029
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0031 0.0245 0.0518
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0031 0.0245 0.0245
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0031 0.0245 0.0518
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0025 0.0179 0.0304
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0073 0.1129
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0017 0.0039
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0017 0.0074 0.1145
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0125
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0014 0.0044 0.0069
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0066 0.0111
Entamoeba histolytica hypothetical protein 0.0025 0.0179 0.2858
Echinococcus multilocularis FTZ F1 alpha 0.0031 0.0245 0.0245
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0025 0.0179 0.2858
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0125
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0012 0.0017 0.0017
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0017 0.0039
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0017 0.0074 0.0156
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0269 0.3205 0.5441
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0245 0.0384
Loa Loa (eye worm) hypothetical protein 0.0031 0.0245 0.0416
Brugia malayi intermediate filament protein 0.0027 0.0202 0.0343
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.062 1
Entamoeba histolytica hypothetical protein 0.0025 0.0179 0.2858
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0394 0.1078
Onchocerca volvulus Huntingtin homolog 0.012 0.1354 1
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0031 0.0245 0.0384
Brugia malayi jmjC domain containing protein 0.0017 0.0073 0.0123
Echinococcus multilocularis deoxyribonuclease 1 2 0.0012 0.0017 0.0017
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0025 0.0179 0.0304
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0017 0.0231
Brugia malayi hypothetical protein 0.0011 0.0003 0.0005
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0017 0.0074 0.0074
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0014 0.0044 0.0044
Brugia malayi jmjC domain containing protein 0.0017 0.0073 0.0123
Loa Loa (eye worm) hypothetical protein 0.0011 0.0003 0.0005
Onchocerca volvulus 0.0029 0.0224 0.1634
Onchocerca volvulus 0.0014 0.0044 0.0305
Brugia malayi orphan nuclear receptor NR2E1 0.0014 0.0044 0.0075
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0061 0.062 1
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Echinococcus granulosus intermediate filament protein 0.0027 0.0202 0.0316
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Schistosoma mansoni RAR-like nuclear receptor 0.0031 0.0245 0.0518
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0017 0.0074 0.0125
Brugia malayi nuclear receptor NHR-88 0.0014 0.0044 0.0075
Echinococcus granulosus ecdysone induced protein 78C 0.0031 0.0245 0.0384
Plasmodium falciparum sphingomyelin synthase 2, putative 0.0025 0.0179 0.2858
Schistosoma mansoni topbp1 0.0011 0.0003 0.0006
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Toxoplasma gondii NAC domain-containing protein 0.004 0.0356 0.5716
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0017 0.0074 0.0115
Brugia malayi Sphingomyelin synthase-related 1 0.0025 0.0179 0.0304
Trichomonas vaginalis sphingomyelin synthetase, putative 0.0025 0.0179 0.2858
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0061 0.062 0.062
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0045 0.0077
Loa Loa (eye worm) hypothetical protein 0.0031 0.0245 0.0416
Entamoeba histolytica hypothetical protein 0.004 0.0366 0.5883
Brugia malayi hypothetical protein 0.012 0.1354 0.2298
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0011 0.0003 0.5
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0012 0.0017 0.0231
Plasmodium vivax basic transcription factor 3b, putative 0.004 0.0356 0.5716
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0035 0.0295 0.0462
Trichomonas vaginalis conserved hypothetical protein 0.0025 0.0179 0.2858
Schistosoma mansoni GTP-binding protein alpha subunit 0.0017 0.0074 0.0156
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0017 0.0074 0.0074
Schistosoma mansoni intermediate filament proteins 0.0027 0.0202 0.0427
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0073 0.0192
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0031 0.0245 0.0518
Schistosoma mansoni hypothetical protein 0.0035 0.0295 0.0623
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0012 0.0017 0.0231
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0017 0.0039
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0012 0.0017 0.0231
Leishmania major phosphatidylcholine:ceramide cholinephosphotransferase 2 0.0025 0.0179 0.0449
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0017 0.0074 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0031 0.0245 0.0416
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Trypanosoma brucei inositol phosphorylceramide synthase 0.0025 0.0179 0.0487
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.062 1
Schistosoma mansoni thyroid hormone receptor 0.0031 0.0245 0.0518
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0391 0.4726 1
Brugia malayi tailless protein 0.0014 0.0044 0.0075
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0391 0.4726 0.741
Echinococcus granulosus neutral sphingomyelinase 0.0012 0.0017 0.0027
Echinococcus multilocularis GPCR, family 2 0.0035 0.0295 0.0295
Brugia malayi DKFZp564C0469 protein 0.0011 0.0003 0.0005
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0017 0.0029
Schistosoma mansoni hypothetical protein 0.0035 0.0295 0.0623
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0356 0.5716
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0012 0.0017 0.0039
Brugia malayi Cytochrome P450 family protein 0.0022 0.0143 0.0243
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0017 0.0074 0.0156
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0303 0.3626 1
Trypanosoma brucei ceramide phosphorylethanolamine synthase 0.0025 0.0179 0.0487
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0073 0.0154
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0303 0.3626 1
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0014 0.0044 0.0075
Schistosoma mansoni ap endonuclease 0.0061 0.062 0.1311
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0017 0.0074 0.1145
Trypanosoma cruzi mitochondrial protein 99, putative 0.0012 0.0017 0.0039
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0075 0.0797 0.1353
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0644 0.101
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0017 0.0074 0.0156
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0011 0.0003 0.0005
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0031 0.0245 0.0416
Echinococcus granulosus nibrin 0.0011 0.0003 0.0005
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0035 0.0295 0.05
Trypanosoma brucei sphingomyelin/ceramide phosphorylethanolamine synthase, bifunctional 0.0025 0.0179 0.0487
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0014 0.0044 0.0069
Brugia malayi jmjC domain containing protein 0.0063 0.0644 0.1093
Trichomonas vaginalis ap endonuclease, putative 0.0061 0.062 1
Schistosoma mansoni gabp alpha 0.0075 0.0797 0.1687
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0012 0.0017 0.0231
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0017 0.0074 0.1145
Loa Loa (eye worm) hypothetical protein 0.012 0.1354 0.2298
Loa Loa (eye worm) hypothetical protein 0.0031 0.0245 0.0416
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0012 0.0017 0.0231
Brugia malayi Phosphatidylcholine:ceramide cholinephosphotransferase 1 0.0485 0.5891 1
Brugia malayi nuclear receptor RXR 0.0016 0.0066 0.0111
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0014 0.0044 0.0093
Brugia malayi Nuclear hormone receptor E75 0.0014 0.0044 0.0075
Plasmodium vivax hypothetical protein, conserved 0.0012 0.0017 0.0231
Brugia malayi nuclear receptor RXR 0.0014 0.0044 0.0075
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0012 0.0017 0.0231
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0073 0.0154
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0202 0.0343
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0017 0.0074 0.1145
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0017 0.0074 0.0125
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0012 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0109 0.1223 0.2077
Brugia malayi Pax transcription activation domain interacting protein 0.0011 0.0003 0.0005
Schistosoma mansoni cpg binding protein 0.0031 0.0244 0.0517
Schistosoma mansoni lamin 0.0027 0.0202 0.0427
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0012 0.0017 0.0027
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0545 0.8784
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0031 0.0245 0.0245
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0035 0.0295 0.0462
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0073 0.0154
Loa Loa (eye worm) hypothetical protein 0.0027 0.0202 0.0343
Echinococcus multilocularis GA binding protein alpha chain 0.0075 0.0797 0.0797
Echinococcus multilocularis neuropeptide receptor A26 0.0524 0.6379 0.6379
Schistosoma mansoni hypothetical protein 0.0364 0.4386 0.928
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0012 0.0017 0.0039
Brugia malayi latrophilin 2 splice variant baaae 0.0075 0.0794 0.1347
Onchocerca volvulus 0.0027 0.0202 0.1472
Loa Loa (eye worm) nuclear hormone receptor 0.0014 0.0044 0.0075
Schistosoma mansoni jumonji/arid domain-containing protein 0.0064 0.0665 0.1406
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0016 0.0066 0.0066
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0012 0.0017 0.0029
Brugia malayi nuclear receptor NHR-88 0.0031 0.0245 0.0416
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0012 0.0017 0.0231
Brugia malayi Fli-1 protein 0.0228 0.2696 0.4576
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0356 0.5716
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0012 0.0017 0.0231
Onchocerca volvulus 0.0012 0.0017 0.0105
Loa Loa (eye worm) hypothetical protein 0.0017 0.0074 0.0125
Schistosoma mansoni spingomyelin synthetase-related 0.0025 0.0179 0.0379
Schistosoma mansoni transcription factor LCR-F1 0.004 0.0366 0.0774
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0012 0.0017 0.0231
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0017 0.0074 0.0156
Schistosoma mansoni hypothetical protein 0.0035 0.0295 0.0623
Loa Loa (eye worm) hypothetical protein 0.0012 0.0017 0.0029
Loa Loa (eye worm) hypothetical protein 0.0025 0.0179 0.0304
Echinococcus multilocularis muscleblind protein 0.0148 0.1702 0.1702
Brugia malayi CXXC zinc finger family protein 0.0029 0.0224 0.038
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0073 0.0123
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0031 0.0245 0.0416
Loa Loa (eye worm) hypothetical protein 0.0485 0.5891 1
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0017 0.0074 0.0156
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0073 0.0114
Plasmodium vivax sphingomyelin synthase 1, putative 0.0025 0.0179 0.2858
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0061 0.062 0.1703
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0031 0.0245 0.0245
Schistosoma mansoni transcription factor btf3 0.004 0.0356 0.0752
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0031 0.0245 0.0245
Trypanosoma brucei RNA editing exonuclease 2 0.0012 0.0017 0.0039
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0012 0.0017 0.0029
Echinococcus multilocularis nuclear receptor nhr 48 0.0014 0.0044 0.0044
Echinococcus granulosus expressed protein 0.0017 0.0074 0.0115
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0012 0.0017 0.0231
Loa Loa (eye worm) hypothetical protein 0.0013 0.0027 0.0047
Brugia malayi Nuclear hormone receptor-like 1 0.0016 0.0066 0.0111
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0052 0.0509 0.1398
Loa Loa (eye worm) hypothetical protein 0.0014 0.0044 0.0075
Schistosoma mansoni nuclear receptor 0.0014 0.0044 0.0093
Echinococcus granulosus lamin dm0 0.0027 0.0202 0.0316
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0016 0.0066 0.0139
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0031 0.0245 0.0384
Toxoplasma gondii hypothetical protein 0.0025 0.0179 0.2858
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0031 0.0245 0.0416
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0012 0.0017 0.0039

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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