Detailed information for compound 579563

Basic information

Technical information
  • TDR Targets ID: 579563
  • Name: methyl (2S)-2-benzamidopropanoate
  • MW: 207.226 | Formula: C11H13NO3
  • H donors: 1 H acceptors: 2 LogP: 1.52 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)[C@@H](NC(=O)c1ccccc1)C
  • InChi: 1S/C11H13NO3/c1-8(11(14)15-2)12-10(13)9-6-4-3-5-7-9/h3-8H,1-2H3,(H,12,13)/t8-/m0/s1
  • InChiKey: QRDFLIILGVFYCF-QMMMGPOBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2S)-2-benzamidopropanoic acid methyl ester
  • (2S)-2-benzamidopropionic acid methyl ester
  • N-benzoylalanine methyl ester
  • methyl (2S)-2-(benzoylamino)propanoate
  • (2S)-2-[(oxo-phenylmethyl)amino]propanoic acid methyl ester
  • (2S)-2-(benzoylamino)propionic acid methyl ester
  • methyl (2S)-2-(phenylcarbonylamino)propanoate
  • ZINC00394817
  • ST5405317

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0737 0.1296
Schistosoma mansoni hypothetical protein 0.0065 0.1046 0.1143
Entamoeba histolytica protein kinase, putative 0.0031 0.0352 0.0462
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0734 0.0801
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0165 0.3117 0.5495
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0902 0.0986
Onchocerca volvulus Cell death protein 3 homolog 0.0066 0.1073 0.107
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.021 0.0227
Trypanosoma cruzi metacaspase, putative 0.002 0.0116 0.2028
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.036 0.6373
Brugia malayi chromobox protein homolog 3 0.0039 0.0501 0.0572
Plasmodium falciparum phd finger protein, putative 0.0058 0.0902 0.1039
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0564 1
Trypanosoma brucei metacaspase MCA2 0.002 0.0116 0.2028
Schistosoma mansoni hypothetical protein 0.014 0.2601 0.2846
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.1369 0.1496
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0564 0.0644
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0449 0.0489
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0056 0.0059
Schistosoma mansoni hypothetical protein 0.0058 0.0902 0.0986
Plasmodium vivax hexose transporter 0.0102 0.1817 0.2094
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0015 0.0014
Brugia malayi Bromodomain containing protein 0.0042 0.058 0.0663
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0339 0.0387
Schistosoma mansoni hypothetical protein 0.0055 0.0831 0.0908
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.1016 0.1788
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0169 0.0183
Brugia malayi PHD-finger family protein 0.0023 0.0174 0.0199
Brugia malayi Sugar transporter family protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0116 0.013
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.1046 0.1195
Trichomonas vaginalis sugar transporter, putative 0.0032 0.036 0.0358
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0116 0.2028
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0561 0.0559
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0564 0.0615
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0339 0.0595
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.002 0.0116 0.0133
Echinococcus granulosus caspase 2 0.0066 0.1073 0.1172
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0352 0.0404
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0444 0.051
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0092 0.0098
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0095 0.1648
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0902 0.1588
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.036 0.6373
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Loa Loa (eye worm) hypothetical protein 0.0025 0.022 0.0249
Trichomonas vaginalis set domain proteins, putative 0.0499 1 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0095 0.1648
Loa Loa (eye worm) hypothetical protein 0.0058 0.0902 0.1028
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0444 0.0779
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.5655 1
Entamoeba histolytica hypothetical protein 0.0023 0.0177 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0501 0.0498
Loa Loa (eye worm) glutaminase 2 0.0274 0.5362 0.6125
Brugia malayi hypothetical protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0662 0.0754
Plasmodium falciparum metacaspase 1 0.002 0.0116 0.0131
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0352 0.0404
Loa Loa (eye worm) animal heme peroxidase 0.0038 0.05 0.0568
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0352 0.0404
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Schistosoma mansoni chromobox protein 0.0069 0.1124 0.1228
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0177 0.0308
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.1231 0.1405
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0092 0.0098
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.2745 0.3004
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.3941 0.4503
Schistosoma mansoni hypothetical protein 0.0015 0.0022 0.0022
Trypanosoma brucei metacaspase 0.002 0.0116 0.2028
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.1016 0.111
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0352 0.0383
Brugia malayi Bromodomain containing protein 0.0064 0.1033 0.1181
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0352 0.0399
Brugia malayi MH1 domain containing protein 0.0017 0.0056 0.0064
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.485 0.5541
Trichomonas vaginalis chromobox protein, putative 0.0069 0.1124 0.1122
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0059 0.0061
Schistosoma mansoni protein kinase 0.0031 0.0352 0.0383
Loa Loa (eye worm) sugar transporter 0.0102 0.1817 0.2073
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0092 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0902 0.1039
Schistosoma mansoni hypothetical protein 0.0457 0.9131 1
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0564 0.0562
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0092 0.0098
Loa Loa (eye worm) acetyltransferase 0.0164 0.3095 0.3534
Schistosoma mansoni smad1 5 8 and 0.0017 0.0056 0.0059
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0352 0.0617
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Echinococcus granulosus caspase 0.002 0.0116 0.0125
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0092 0.0098
Entamoeba histolytica hypothetical protein 0.0036 0.045 0.0639
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.1817 0.1987
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0116 0.0125
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0092 0.1593
Echinococcus multilocularis caspase 2 0.0066 0.1073 0.1172
Loa Loa (eye worm) Smad1 0.0017 0.0056 0.0061
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0097 0.0166
Brugia malayi PHD-finger family protein 0.0031 0.0341 0.0389
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0352 0.0383
Plasmodium falciparum hexose transporter 0.0102 0.1817 0.2094
Plasmodium vivax metacaspase 1, putative 0.002 0.0116 0.0131
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0018 0.0016
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0092 0.0102
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0312 0.0339
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0352 0.0404
Plasmodium falciparum metacaspase-like protein 0.002 0.0116 0.0131
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Echinococcus granulosus chromobox protein 1 0.0069 0.1124 0.1228
Trichomonas vaginalis sugar transporter, putative 0.0032 0.036 0.0358
Echinococcus multilocularis zinc finger protein 0.0025 0.023 0.025
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0606 0.0697
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0352 0.6225
Brugia malayi AF-10 protein 0.0019 0.0097 0.0111
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0339 0.093
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0606 0.1068
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0015 0.0014
Plasmodium vivax JmjC domain containing protein 0.0019 0.0092 0.0103
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Loa Loa (eye worm) hypothetical protein 0.0023 0.0177 0.0199
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0438 0.8752 1
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.1371 0.1499
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0737 0.0735
Echinococcus multilocularis peregrin 0.0064 0.1033 0.1129
Brugia malayi major facilitator superfamily protein 0.0014 0.0003 0.0003
Plasmodium falciparum protein kinase 7 0.0289 0.5669 0.6542
Brugia malayi Sugar transporter family protein 0.0014 0.0003 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0095 0.0107
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0309 0.0336
Brugia malayi hypothetical protein 0.0014 0.0003 0.0003
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0177 0.0174
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0095 0.0109
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0095 0.1648
Trypanosoma brucei metacaspase 5, putative 0.002 0.0116 0.2028
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0177 0.0191
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Schistosoma mansoni hypothetical protein 0.017 0.3213 0.3517
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0095 0.0164
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0501 0.0498
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.1817 0.3201
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0056 0.0061
Schistosoma mansoni smad 0.0017 0.0056 0.0059
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0056 0.0059
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.1274 0.1393
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0444 0.051
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0734 0.2801
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0177 0.0308
Plasmodium vivax hypothetical protein, conserved 0.002 0.0116 0.0131
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.1046 0.1143
Loa Loa (eye worm) hypothetical protein 0.0065 0.1046 0.1192
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0564 0.0615
Brugia malayi Bromodomain containing protein 0.0081 0.1377 0.1574
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0177 0.0325
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0015 0.0014
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0312 0.0339
Brugia malayi Cell death protein 3 precursor 0.0066 0.1073 0.1226
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.1274 0.2243
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0092 0.0098
Echinococcus multilocularis chromobox protein 1 0.0069 0.1124 0.1228
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 0.2372
Schistosoma mansoni zinc finger protein 0.0025 0.023 0.025
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Echinococcus multilocularis caspase 8 0.002 0.0116 0.0125
Schistosoma mansoni smad1 5 8 and 0.0017 0.0056 0.0059
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0137 0.0155
Echinococcus multilocularis chromobox protein 1 0.0069 0.1124 0.1228
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.1231 0.1346
Schistosoma mansoni chromobox protein 0.0069 0.1124 0.1228
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0092 0.0098
Brugia malayi hypothetical protein 0.0038 0.05 0.0571
Brugia malayi jmjC domain containing protein 0.0019 0.0092 0.0105
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0174 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.045 0.049
Brugia malayi CXXC zinc finger family protein 0.0032 0.0368 0.042
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0564 1
Echinococcus granulosus geminin 0.017 0.3213 0.3517
Brugia malayi Smad1 0.0017 0.0056 0.0064
Onchocerca volvulus 0.0055 0.0831 0.0829
Echinococcus granulosus histone acetyltransferase KAT2B 0.0157 0.2952 0.3231
Leishmania major glucose transporter, lmgt1 0.0032 0.036 0.6373
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0564 0.0615
Echinococcus granulosus caspase 8 0.002 0.0116 0.0125
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.1124 0.1282
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.1046 0.1192
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.2745 0.3004
Echinococcus multilocularis apoptotic protease activating factor 1 0.0046 0.0662 0.0722
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0056 0.0059
Schistosoma mansoni hypothetical protein 0.0046 0.0662 0.0722
Brugia malayi jmjC domain containing protein 0.0074 0.1231 0.1407
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0092 0.0098
Leishmania major hypothetical protein, conserved 0.0015 0.0022 0.0352
Trypanosoma cruzi metacaspase, putative 0.002 0.0116 0.2028
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0246 0.0271
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0095 0.0173
Brugia malayi MH2 domain containing protein 0.0017 0.0056 0.0064
Schistosoma mansoni peroxidasin 0.0038 0.05 0.0544
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0564 1
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0339 0.0369
Schistosoma mansoni peroxidasin 0.0038 0.05 0.0544
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.045 0.049
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.1817 0.1814
Loa Loa (eye worm) hypothetical protein 0.0076 0.1274 0.1453
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0095 0.0728
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 0.212
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0092 0.0098
Loa Loa (eye worm) hypothetical protein 0.0031 0.0339 0.0385
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0177 0.3105
Loa Loa (eye worm) hypothetical protein 0.0019 0.0092 0.0102
Onchocerca volvulus 0.003 0.0329 0.0326
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0177 0.3105
Echinococcus multilocularis General substrate transporter 0.0088 0.152 0.1662
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0564 0.0562
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0352 0.0617
Entamoeba histolytica hypothetical protein 0.0036 0.045 0.0639
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0106 0.0396
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0902 0.1588
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0059 0.0061
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.1231 0.1346
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0339 0.0369
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Loa Loa (eye worm) hypothetical protein 0.003 0.0329 0.0373
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.5655 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Echinococcus granulosus cpg binding protein 0.0036 0.0445 0.0484
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 0.1468
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0177 0.0201
Onchocerca volvulus Alhambra homolog 0.0058 0.0902 0.09
Schistosoma mansoni hypothetical protein 0.0036 0.045 0.049
Echinococcus multilocularis cpg binding protein 0.0036 0.0445 0.0484
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0177 0.0325
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0056 0.0059
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.1046 0.1143
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0561 0.0559
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0003 0.0003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.1231 0.1346
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.2612 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Brugia malayi MH1 domain containing protein 0.0017 0.0056 0.0064
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0092 0.0098
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.2745 0.3134
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0339 0.0387
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0092 0.1593
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.1369 0.1496
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0246 0.0559
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.021 0.0227
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.1061 0.1159
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0246 0.0281
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0092 0.0098
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0831 0.095
Onchocerca volvulus 0.0038 0.05 0.0497
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Brugia malayi MH2 domain containing protein 0.0249 0.485 0.5542
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0059 0.0061
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Onchocerca volvulus Peroxidasin homolog 0.0038 0.05 0.0497
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0564 0.0615
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.021 0.0227
Brugia malayi Peroxidasin 0.0038 0.05 0.0571
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0339 0.0337
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0056 0.0061
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Brugia malayi hypothetical protein 0.0046 0.0662 0.0756
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Onchocerca volvulus 0.0032 0.0368 0.0365
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0137 0.0155
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0352 0.0404
Toxoplasma gondii protein kinase, putative 0.0289 0.5669 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Trypanosoma cruzi hexose transporter, putative 0.0032 0.036 0.6373
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.019 0.3625 0.3968
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.2612 0.4869
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0116 0.0201
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.2745 0.3136
Loa Loa (eye worm) hypothetical protein 0.0019 0.0092 0.0102
Entamoeba histolytica hypothetical protein 0.0036 0.045 0.0639
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0449 0.0489
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0164 0.3095 0.3387
Schistosoma mansoni protein kinase 0.0031 0.0352 0.0383
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0339 0.0369
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0116 0.0125
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0339 0.0369
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0737 0.1296
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.1274 0.1468
Loa Loa (eye worm) hypothetical protein 0.0099 0.1757 0.2006
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0246 0.0281
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0177 0.3105
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0737 0.0735
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0092 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.1154 0.1262
Schistosoma mansoni hypothetical protein 0.0021 0.0133 0.0143
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0095 0.0101
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0092 0.0098
Trypanosoma brucei ISWI complex protein 0.0015 0.0022 0.0352
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0177 0.0191
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.1274 0.2243
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.045 0.049
Trichomonas vaginalis glutaminase, putative 0.0274 0.5362 0.5361
Brugia malayi major facilitator superfamily protein 0.0014 0.0003 0.0003
Echinococcus granulosus General substrate transporter 0.0088 0.152 0.1662
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0737 0.0804
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0116 0.2028
Schistosoma mansoni hypothetical protein 0.0102 0.1817 0.1987
Loa Loa (eye worm) blistered cuticle protein 3 0.0038 0.05 0.0568
Schistosoma mansoni glutaminase 0.0274 0.5362 0.5871
Trichomonas vaginalis chromobox protein, putative 0.0069 0.1124 0.1122
Echinococcus granulosus GPCR family 2 0.0065 0.1046 0.1143
Echinococcus granulosus apoptotic protease activating factor 1 0.0046 0.0662 0.0722
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0177 0.0191
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0352 0.0402
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Brugia malayi Cam kinase protein 1 0.0031 0.0352 0.0402
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Brugia malayi Pre-SET motif family protein 0.0438 0.8752 1
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0564 0.0615
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Schistosoma mansoni glucose transport protein 0.0102 0.1817 0.1987
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.1369 0.1496
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.2745 0.3004
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0177 0.0191
Onchocerca volvulus 0.0038 0.05 0.0497
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0352 0.035
Brugia malayi MH2 domain containing protein 0.0017 0.0056 0.0064
Brugia malayi Pre-SET motif family protein 0.0063 0.1016 0.1161
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0368 0.0417
Trypanosoma cruzi hexose transporter, putative 0.0032 0.036 0.6373
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0092 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.036 0.0358
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0564 0.0615
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0606 0.0919
Echinococcus granulosus survival motor neuron protein 1 0.0267 0.5223 0.5719
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0097 0.168
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.2745 0.3004
Toxoplasma gondii hypothetical protein 0.0026 0.0246 0.043
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0564 0.0562
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0339 0.0439
Giardia lamblia Fructose-bisphosphate aldolase 0.0288 0.5655 1
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0095 0.0101
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.1274 0.1393
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0056 0.0059
Schistosoma mansoni zinc finger protein 0.0015 0.0022 0.0022
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0116 0.0125
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0269 0.0266
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Brugia malayi Heterochromatin protein 1 0.0069 0.1124 0.1284
Trypanosoma brucei glucose transporter 1E 0.0032 0.036 0.6373
Loa Loa (eye worm) hypothetical protein 0.0205 0.3941 0.4501
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0092 0.1593
Brugia malayi hypothetical protein 0.0036 0.045 0.0514
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0092 0.0158
Echinococcus granulosus chromobox protein 1 0.0069 0.1124 0.1228
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0564 0.0844
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0097 0.168
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.1369 0.1496
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0269 0.0266
Brugia malayi jmjC domain containing protein 0.0019 0.0092 0.0105
Schistosoma mansoni cpg binding protein 0.0036 0.0445 0.0484
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0064 0.1087
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0352 0.0404
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Brugia malayi jmjC domain containing protein 0.019 0.3625 0.4142
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Entamoeba histolytica hypothetical protein 0.0036 0.045 0.0639
Schistosoma mansoni hypothetical protein 0.0065 0.1046 0.1143
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0352 0.0404
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0564 0.0615
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0095 0.0355
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.3941 0.4503
Echinococcus multilocularis smad 0.0017 0.0056 0.0059
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Loa Loa (eye worm) animal heme peroxidase 0.0038 0.05 0.0568
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0734 0.0801
Echinococcus granulosus dnaJ subfamily B 0.0457 0.9131 1
Brugia malayi jmjC domain containing protein 0.0019 0.0092 0.0105
Trichomonas vaginalis sugar transporter, putative 0.0032 0.036 0.0358
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0095 0.0093
Loa Loa (eye worm) hypothetical protein 0.0031 0.0339 0.0385
Giardia lamblia PHD finger protein 15 0.0058 0.0902 0.1592
Onchocerca volvulus 0.0038 0.05 0.0497
Schistosoma mansoni Smad4 0.0017 0.0056 0.0059
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0095 0.0107
Leishmania major metacaspase, putative 0.002 0.0116 0.2028
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.1046 0.1143
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0015 0.0014
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0177 0.0201
Loa Loa (eye worm) hypothetical protein 0.0071 0.1169 0.1333
Loa Loa (eye worm) hypothetical protein 0.0066 0.1073 0.1223
Treponema pallidum fructose-bisphosphate aldolase 0.0288 0.5655 1
Schistosoma mansoni protein kinase 0.0031 0.0352 0.0383
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0564 0.0615
Schistosoma mansoni glucose transport protein 0.0102 0.1817 0.1987
Brugia malayi hypothetical protein 0.0267 0.5223 0.5967
Onchocerca volvulus Peroxidasin homolog 0.0038 0.05 0.0497
Schistosoma mansoni hypothetical protein 0.0065 0.1046 0.1143
Trichomonas vaginalis glucose transporter, putative 0.0032 0.036 0.0358
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0097 0.0166
Loa Loa (eye worm) glutaminase 0.0274 0.5362 0.6125
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0018 0.0016
Schistosoma mansoni survival motor neuron protein 0.0055 0.0831 0.0908
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0059 0.0061
Loa Loa (eye worm) hypothetical protein 0.0042 0.0564 0.0642
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0095 0.0106
Schistosoma mansoni ap endonuclease 0.0019 0.0095 0.0101
Loa Loa (eye worm) hypothetical protein 0.0049 0.0708 0.0806
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 0.2372
Onchocerca volvulus Peroxidase homolog 0.0038 0.05 0.0497
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.2612 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Echinococcus multilocularis GPCR, family 2 0.0065 0.1046 0.1143
Trypanosoma cruzi hexose transporter 0.0032 0.036 0.6373
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0954 0.1042
Echinococcus granulosus peregrin 0.0064 0.1033 0.1129
Trypanosoma cruzi ISWI complex protein 0.0015 0.0022 0.0352
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0116 0.0125
Schistosoma mansoni glucose transport protein 0.0102 0.1817 0.1987
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Echinococcus granulosus zinc finger protein 0.0025 0.023 0.025
Brugia malayi F/Y-rich N-terminus family protein 0.0033 0.0386 0.0441
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Onchocerca volvulus 0.0046 0.0662 0.066
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0095 0.1648
Toxoplasma gondii exonuclease III APE 0.0019 0.0095 0.0163
Brugia malayi PHD-finger family protein 0.0058 0.0902 0.1031
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.1274 0.466
Echinococcus multilocularis caspase 0.002 0.0116 0.0125
Schistosoma mansoni cpg binding protein 0.0036 0.0445 0.0484
Schistosoma mansoni hypothetical protein 0.0019 0.0097 0.0103
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0177 0.0202
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.036 0.0358
Leishmania major glucose transporter, lmgt3 0.0032 0.036 0.6373
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0133 0.0149
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0564 1
Schistosoma mansoni ap endonuclease 0.0019 0.0095 0.0101
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0352 0.0617
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0095 0.0093
Echinococcus granulosus Smad4 0.0017 0.0056 0.0059
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0902 0.0986
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0116 0.0201
Onchocerca volvulus Peroxidase homolog 0.0038 0.05 0.0497
Brugia malayi Blistered cuticle protein 3 0.0038 0.05 0.0571
Brugia malayi acetyltransferase, GNAT family protein 0.0164 0.3095 0.3536
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0501 0.0498
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.2745 0.3004
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0902 0.0986
Loa Loa (eye worm) animal heme peroxidase 0.0038 0.05 0.0568
Brugia malayi jmjC domain containing protein 0.0019 0.0092 0.0105
Brugia malayi glutaminase DH11.1 0.0274 0.5362 0.6127
Entamoeba histolytica protein kinase, putative 0.0031 0.0352 0.0462
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0164 0.3095 0.3387
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Loa Loa (eye worm) animal heme peroxidase 0.0038 0.05 0.0568
Schistosoma mansoni cpg binding protein 0.0032 0.0368 0.04
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.1016 0.111
Plasmodium vivax SET domain protein, putative 0.0063 0.1016 0.117
Brugia malayi Sugar transporter family protein 0.0102 0.1817 0.2075
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0561 0.0559
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0075 0.1248 0.1364
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.2177 0.2485
Echinococcus multilocularis peroxidasin 0.0038 0.05 0.0544
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0734 0.2801
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.019 0.3625 0.3968
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.485 0.5541
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0119 0.0116
Leishmania major glucose transporter, lmgt2 0.0032 0.036 0.6373
Schistosoma mansoni bromodomain containing protein 0.0069 0.1135 0.124
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0092 0.0158
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.1157 0.1265
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.036 0.6373
Brugia malayi hypothetical protein 0.0014 0.0003 0.0003
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0116 0.0125
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.1274 0.1393
Echinococcus multilocularis survival motor neuron protein 1 0.0267 0.5223 0.5719
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.2745 0.3004
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.036 0.6373
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0116 0.0201
Loa Loa (eye worm) hypothetical protein 0.0081 0.1369 0.1561
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0352 0.0404
Echinococcus granulosus jumonji domain containing protein 0.0081 0.1371 0.1499
Brugia malayi CHD4 protein 0.0015 0.0015 0.0017
Mycobacterium ulcerans glutaminase 0.0274 0.5362 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.2601 0.2972
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0005
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Loa Loa (eye worm) hypothetical protein 0.0267 0.5223 0.5966
Schistosoma mansoni caspase-7 (C14 family) 0.0066 0.1073 0.1172
Leishmania major protein kinase, putative 0.0031 0.0352 0.6225
Trypanosoma cruzi metacaspase, putative 0.002 0.0116 0.2028
Echinococcus granulosus peroxidasin 0.0038 0.05 0.0544
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0902 0.1028
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0153 0.0172
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Trypanosoma cruzi ISWI complex protein 0.0015 0.0022 0.0352
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Trypanosoma cruzi hexose transporter, putative 0.0032 0.036 0.6373
Onchocerca volvulus 0.0075 0.1248 0.1246
Plasmodium falciparum mitogen-activated protein kinase 2 0.0165 0.3117 0.3595
Schistosoma mansoni hypothetical protein 0.0065 0.1046 0.1143
Schistosoma mansoni hypothetical protein 0.017 0.3213 0.3517
Plasmodium falciparum protein kinase 6 0.0434 0.8664 1
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0352 0.0404
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0352 0.0399
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0088 0.0085
Echinococcus granulosus phd:f box containing protein 0.0019 0.0092 0.0098
Onchocerca volvulus Dual oxidase homolog 0.0038 0.05 0.0497
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0564 0.0993
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Brugia malayi Latrophilin receptor protein 2 0.0065 0.1046 0.1195
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Trypanosoma brucei Metacaspase-4 0.002 0.0116 0.2028
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0177 0.0283
Echinococcus multilocularis Smad4 0.0017 0.0056 0.0059
Trypanosoma cruzi metacaspase, putative 0.002 0.0116 0.2028
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.1046 0.1143
Schistosoma mansoni smad1 5 8 and 0.0017 0.0056 0.0059
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0088 0.0085
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0169 0.0183
Loa Loa (eye worm) hypothetical protein 0.014 0.2601 0.297
Loa Loa (eye worm) hypothetical protein 0.0039 0.0501 0.0569
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0734 0.2504
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0106 0.0396
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.1138 0.2004
Leishmania major hypothetical protein, conserved 0.0019 0.0092 0.1593
Echinococcus granulosus smad 0.0017 0.0056 0.0059
Trichomonas vaginalis glucose transporter, putative 0.0032 0.036 0.0358
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.1061 0.1159
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.2745 0.3004
Brugia malayi Probable ClpP-like protease 0.0076 0.1274 0.1455
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0092 0.0103
Trypanosoma brucei glucose transporter 2A 0.0032 0.036 0.6373
Loa Loa (eye worm) hypothetical protein 0.0045 0.0631 0.0718
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0165 0.3117 0.3595
Echinococcus multilocularis dnaJ subfamily B 0.0457 0.9131 1
Plasmodium vivax CDK-related protein kinase 6, putative 0.0434 0.8664 1
Echinococcus multilocularis geminin 0.017 0.3213 0.3517
Trypanosoma brucei metacaspase MCA3 0.002 0.0116 0.2028
Schistosoma mansoni jumonji domain containing protein 0.0151 0.282 0.3086
Loa Loa (eye worm) hypothetical protein 0.0031 0.0352 0.0399
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.3941 0.4501
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0737 0.0848
Onchocerca volvulus Chorion peroxidase homolog 0.0038 0.05 0.0497

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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