Detailed information for compound 579564

Basic information

Technical information
  • TDR Targets ID: 579564
  • Name: methyl 2-benzamidopropanoate
  • MW: 207.226 | Formula: C11H13NO3
  • H donors: 1 H acceptors: 2 LogP: 1.52 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C(NC(=O)c1ccccc1)C
  • InChi: 1S/C11H13NO3/c1-8(11(14)15-2)12-10(13)9-6-4-3-5-7-9/h3-8H,1-2H3,(H,12,13)
  • InChiKey: QRDFLIILGVFYCF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-benzamidopropanoic acid methyl ester
  • 2-benzamidopropionic acid methyl ester
  • N-benzoylalanine methyl ester
  • methyl 2-(benzoylamino)propanoate
  • 2-[(oxo-phenylmethyl)amino]propanoic acid methyl ester
  • 2-(benzoylamino)propionic acid methyl ester
  • methyl 2-(phenylcarbonylamino)propanoate
  • 7244-67-9
  • 7260-27-7
  • L-Alanine, N-benzoyl-, methyl ester
  • Alanine, N-benzoyl-, methyl ester, L-
  • EINECS 230-649-7
  • Methyl N-benzoyl-L-alaninate
  • N-BENZOYL-L-ALANINE, METHYL ESTER
  • 2-Benzoylaminopropionic acid, methyl ester
  • NSC173195
  • B3380_SIGMA
  • N-Benzoyl-L-alanine methyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0032 0.0368 0.0365
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0021 0.0137 0.0155
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Brugia malayi hypothetical protein 0.0046 0.0662 0.0756
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0116 0.0201
Toxoplasma gondii protein kinase, putative 0.0289 0.5669 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.019 0.3625 0.3968
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0141 0.2612 0.4869
Trypanosoma cruzi hexose transporter, putative 0.0032 0.036 0.6373
Plasmodium falciparum calcium-dependent protein kinase 5 0.0031 0.0352 0.0404
Onchocerca volvulus Peroxidasin homolog 0.0038 0.05 0.0497
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0564 0.0615
Brugia malayi MH2 domain containing protein 0.0249 0.485 0.5542
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0059 0.0061
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0055 0.0831 0.095
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Onchocerca volvulus 0.0038 0.05 0.0497
Echinococcus multilocularis lysine specific demethylase 6a 0.0019 0.0092 0.0098
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0056 0.0061
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0031 0.0339 0.0337
Brugia malayi Peroxidasin 0.0038 0.05 0.0571
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.021 0.0227
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.021 0.0227
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0026 0.0246 0.0559
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0092 0.1593
Echinococcus granulosus histone lysine methyltransferase setb 0.0081 0.1369 0.1496
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0147 0.2745 0.3134
Schistosoma mansoni phd/f-box containing protein 0.0019 0.0092 0.0098
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0031 0.0339 0.0387
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0246 0.0281
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0066 0.1061 0.1159
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.1231 0.1346
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0561 0.0559
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0003 0.0003
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0177 0.0325
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0056 0.0059
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0065 0.1046 0.1143
Echinococcus multilocularis cpg binding protein 0.0036 0.0445 0.0484
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Brugia malayi MH1 domain containing protein 0.0017 0.0056 0.0064
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0141 0.2612 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 0.1468
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Schistosoma mansoni hypothetical protein 0.0036 0.045 0.049
Onchocerca volvulus Alhambra homolog 0.0058 0.0902 0.09
Plasmodium falciparum lysine--tRNA ligase 0.0023 0.0177 0.0201
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0339 0.0369
Loa Loa (eye worm) hypothetical protein 0.003 0.0329 0.0373
Schistosoma mansoni jumonji/arid domain-containing protein 0.0074 0.1231 0.1346
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0059 0.0061
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 1
Echinococcus granulosus cpg binding protein 0.0036 0.0445 0.0484
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.5655 1
Echinococcus multilocularis General substrate transporter 0.0088 0.152 0.1662
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0023 0.0177 0.3105
Onchocerca volvulus 0.003 0.0329 0.0326
Loa Loa (eye worm) hypothetical protein 0.0019 0.0092 0.0102
Leishmania major lysyl-tRNA synthetase, putative 0.0023 0.0177 0.3105
Loa Loa (eye worm) hypothetical protein 0.0031 0.0339 0.0385
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0902 0.1588
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0019 0.0106 0.0396
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0031 0.0352 0.0617
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0564 0.0562
Entamoeba histolytica hypothetical protein 0.0036 0.045 0.0639
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0095 0.0728
Loa Loa (eye worm) hypothetical protein 0.0076 0.1274 0.1453
Trichomonas vaginalis conserved hypothetical protein 0.0102 0.1817 0.1814
Schistosoma mansoni phosphatidylserine receptor 0.0019 0.0092 0.0098
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 0.212
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0564 1
Schistosoma mansoni peroxidasin 0.0038 0.05 0.0544
Brugia malayi MH2 domain containing protein 0.0017 0.0056 0.0064
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0095 0.0173
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.045 0.049
Schistosoma mansoni peroxidasin 0.0038 0.05 0.0544
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0031 0.0339 0.0369
Echinococcus multilocularis apoptotic protease activating factor 1 0.0046 0.0662 0.0722
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.2745 0.3004
Trypanosoma cruzi metacaspase, putative 0.002 0.0116 0.2028
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0026 0.0246 0.0271
Leishmania major hypothetical protein, conserved 0.0015 0.0022 0.0352
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Echinococcus multilocularis JmjC domain containing protein 4 0.0019 0.0092 0.0098
Schistosoma mansoni hypothetical protein 0.0046 0.0662 0.0722
Brugia malayi jmjC domain containing protein 0.0074 0.1231 0.1407
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0056 0.0059
Echinococcus granulosus histone acetyltransferase KAT2B 0.0157 0.2952 0.3231
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 1
Leishmania major glucose transporter, lmgt1 0.0032 0.036 0.6373
Onchocerca volvulus 0.0055 0.0831 0.0829
Brugia malayi Smad1 0.0017 0.0056 0.0064
Echinococcus granulosus geminin 0.017 0.3213 0.3517
Loa Loa (eye worm) latrophilin receptor protein 2 0.0065 0.1046 0.1192
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.1124 0.1282
Echinococcus granulosus caspase 8 0.002 0.0116 0.0125
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0564 0.0615
Brugia malayi hypothetical protein 0.0038 0.05 0.0571
Echinococcus multilocularis phd:f box containing protein 0.0019 0.0092 0.0098
Schistosoma mansoni chromobox protein 0.0069 0.1124 0.1228
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.045 0.049
Brugia malayi CXXC zinc finger family protein 0.0032 0.0368 0.042
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0564 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0174 0.0196
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0003 0.0003
Brugia malayi jmjC domain containing protein 0.0019 0.0092 0.0105
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 0.2372
Echinococcus multilocularis chromobox protein 1 0.0069 0.1124 0.1228
Plasmodium vivax hypothetical protein, conserved 0.0021 0.0137 0.0155
Echinococcus granulosus lysine specific demethylase 5A 0.0074 0.1231 0.1346
Echinococcus multilocularis chromobox protein 1 0.0069 0.1124 0.1228
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Echinococcus multilocularis caspase 8 0.002 0.0116 0.0125
Schistosoma mansoni smad1 5 8 and 0.0017 0.0056 0.0059
Schistosoma mansoni zinc finger protein 0.0025 0.023 0.025
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0015 0.0015 0.0014
Echinococcus granulosus calcium dependent protein kinase 0.0029 0.0312 0.0339
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0023 0.0177 0.0325
Brugia malayi Bromodomain containing protein 0.0081 0.1377 0.1574
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0019 0.0092 0.0098
Brugia malayi Cell death protein 3 precursor 0.0066 0.1073 0.1226
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.1274 0.2243
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0056 0.0061
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0056 0.0059
Schistosoma mansoni smad 0.0017 0.0056 0.0059
Toxoplasma gondii facilitative glucose transporter GT1 0.0102 0.1817 0.3201
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0095 0.0164
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0501 0.0498
Loa Loa (eye worm) hypothetical protein 0.0065 0.1046 0.1192
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0065 0.1046 0.1143
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0564 0.0615
Plasmodium vivax hypothetical protein, conserved 0.002 0.0116 0.0131
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.005 0.0734 0.2801
Toxoplasma gondii lysine-tRNA ligase 0.0023 0.0177 0.0308
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0076 0.1274 0.1393
Plasmodium vivax proline--tRNA ligase, putative 0.0036 0.0444 0.051
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0095 0.1648
Trypanosoma brucei metacaspase 5, putative 0.002 0.0116 0.2028
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0177 0.0174
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0095 0.0109
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0029 0.0309 0.0336
Brugia malayi Sugar transporter family protein 0.0014 0.0003 0.0003
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0095 0.0107
Brugia malayi hypothetical protein 0.0014 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.017 0.3213 0.3517
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Echinococcus multilocularis lysyl tRNA synthetase 0.0023 0.0177 0.0191
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.005 0.0737 0.0735
Echinococcus multilocularis jumonji domain containing protein 0.0081 0.1371 0.1499
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0438 0.8752 1
Plasmodium falciparum protein kinase 7 0.0289 0.5669 0.6542
Echinococcus multilocularis peregrin 0.0064 0.1033 0.1129
Brugia malayi major facilitator superfamily protein 0.0014 0.0003 0.0003
Echinococcus multilocularis zinc finger protein 0.0025 0.023 0.025
Plasmodium falciparum histone acetyltransferase GCN5 0.0044 0.0606 0.0697
Trichomonas vaginalis sugar transporter, putative 0.0032 0.036 0.0358
Echinococcus granulosus chromobox protein 1 0.0069 0.1124 0.1228
Loa Loa (eye worm) hypothetical protein 0.0023 0.0177 0.0199
Plasmodium vivax JmjC domain containing protein 0.0019 0.0092 0.0103
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Giardia lamblia Histone acetyltransferase GCN5 0.0044 0.0606 0.1068
Loa Loa (eye worm) CHromoDomain protein family member 0.0015 0.0015 0.0014
Brugia malayi AF-10 protein 0.0019 0.0097 0.0111
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0031 0.0352 0.6225
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0031 0.0339 0.093
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0092 0.0102
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0018 0.0016
Plasmodium falciparum calcium-dependent protein kinase 1 0.0031 0.0352 0.0404
Plasmodium falciparum metacaspase-like protein 0.002 0.0116 0.0131
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Echinococcus multilocularis calcium dependent protein kinase 0.0029 0.0312 0.0339
Toxoplasma gondii PHD-finger domain-containing protein 0.0019 0.0097 0.0166
Loa Loa (eye worm) Smad1 0.0017 0.0056 0.0061
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0019 0.0092 0.1593
Echinococcus multilocularis caspase 2 0.0066 0.1073 0.1172
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.002 0.0116 0.0125
Plasmodium vivax metacaspase 1, putative 0.002 0.0116 0.0131
Plasmodium falciparum hexose transporter 0.0102 0.1817 0.2094
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0031 0.0352 0.0383
Brugia malayi PHD-finger family protein 0.0031 0.0341 0.0389
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Schistosoma mansoni smad1 5 8 and 0.0017 0.0056 0.0059
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0031 0.0352 0.0617
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0102 0.1817 0.1987
Echinococcus granulosus caspase 0.002 0.0116 0.0125
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Entamoeba histolytica hypothetical protein 0.0036 0.045 0.0639
Echinococcus multilocularis jumonji domain containing 1A 0.0019 0.0092 0.0098
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0902 0.1039
Schistosoma mansoni protein phosphatase 2C 0.0019 0.0092 0.0098
Loa Loa (eye worm) sugar transporter 0.0102 0.1817 0.2073
Schistosoma mansoni protein kinase 0.0031 0.0352 0.0383
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0059 0.0061
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Trichomonas vaginalis chromobox protein, putative 0.0069 0.1124 0.1122
Schistosoma mansoni jumonji domain containing protein 0.0019 0.0092 0.0098
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0564 0.0562
Loa Loa (eye worm) acetyltransferase 0.0164 0.3095 0.3534
Schistosoma mansoni hypothetical protein 0.0457 0.9131 1
Brugia malayi Bromodomain containing protein 0.0064 0.1033 0.1181
Trypanosoma brucei metacaspase 0.002 0.0116 0.2028
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0063 0.1016 0.111
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0352 0.0383
Loa Loa (eye worm) MH2 domain-containing protein 0.0249 0.485 0.5541
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Brugia malayi MH1 domain containing protein 0.0017 0.0056 0.0064
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0031 0.0352 0.0399
Echinococcus granulosus JmjC domain containing protein 4 0.0019 0.0092 0.0098
Loa Loa (eye worm) jmjC domain-containing protein 0.0074 0.1231 0.1405
Giardia lamblia Lysyl-tRNA synthetase 0.0023 0.0177 0.0308
Brugia malayi Calcitonin receptor-like protein seb-1 0.0205 0.3941 0.4503
Schistosoma mansoni hypothetical protein 0.0015 0.0022 0.0022
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.2745 0.3004
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0031 0.0352 0.0404
Loa Loa (eye worm) animal heme peroxidase 0.0038 0.05 0.0568
Plasmodium falciparum metacaspase 1 0.002 0.0116 0.0131
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Plasmodium vivax calcium-dependent protein kinase, putative 0.0031 0.0352 0.0404
Schistosoma mansoni chromobox protein 0.0069 0.1124 0.1228
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0288 0.5655 1
Entamoeba histolytica hypothetical protein 0.0023 0.0177 0.0147
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0501 0.0498
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0036 0.0444 0.0779
Trichomonas vaginalis set domain proteins, putative 0.0499 1 1
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0095 0.1648
Loa Loa (eye worm) hypothetical protein 0.0058 0.0902 0.1028
Loa Loa (eye worm) hypothetical protein 0.0025 0.022 0.0249
Brugia malayi hypothetical protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) glutaminase 2 0.0274 0.5362 0.6125
Loa Loa (eye worm) hypothetical protein 0.0046 0.0662 0.0754
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0031 0.0352 0.0404
Plasmodium falciparum proline--tRNA ligase 0.0036 0.0444 0.051
Leishmania major glucose transporter/membrane transporter D2, putative 0.0032 0.036 0.6373
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0902 0.1588
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Echinococcus granulosus jumonji domain containing 1A 0.0019 0.0092 0.0098
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0095 0.1648
Giardia lamblia Prolyl-tRNA synthetase 0.0031 0.0339 0.0595
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0564 0.0615
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0561 0.0559
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0116 0.2028
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0065 0.1046 0.1195
Trichomonas vaginalis sugar transporter, putative 0.0032 0.036 0.0358
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.002 0.0116 0.0133
Echinococcus granulosus caspase 2 0.0066 0.1073 0.1172
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0063 0.1016 0.1788
Schistosoma mansoni hypothetical protein 0.0055 0.0831 0.0908
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0031 0.0339 0.0387
Brugia malayi Bromodomain containing protein 0.0042 0.058 0.0663
Brugia malayi Sugar transporter family protein 0.0014 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.002 0.0116 0.013
Brugia malayi PHD-finger family protein 0.0023 0.0174 0.0199
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0169 0.0183
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0081 0.1369 0.1496
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0564 0.0644
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0015 0.0015 0.0014
Plasmodium vivax hexose transporter 0.0102 0.1817 0.2094
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0449 0.0489
Schistosoma mansoni hypothetical protein 0.0058 0.0902 0.0986
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0056 0.0059
Schistosoma mansoni hypothetical protein 0.014 0.2601 0.2846
Plasmodium falciparum phd finger protein, putative 0.0058 0.0902 0.1039
Trypanosoma brucei metacaspase MCA2 0.002 0.0116 0.2028
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0564 1
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0165 0.3117 0.5495
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0902 0.0986
Echinococcus multilocularis peptidase Clp (S14 family) 0.005 0.0734 0.0801
Schistosoma mansoni hypothetical protein 0.0065 0.1046 0.1143
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.005 0.0737 0.1296
Entamoeba histolytica protein kinase, putative 0.0031 0.0352 0.0462
Brugia malayi chromobox protein homolog 3 0.0039 0.0501 0.0572
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.036 0.6373
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.021 0.0227
Onchocerca volvulus Cell death protein 3 homolog 0.0066 0.1073 0.107
Trypanosoma cruzi metacaspase, putative 0.002 0.0116 0.2028
Trypanosoma brucei metacaspase MCA3 0.002 0.0116 0.2028
Echinococcus multilocularis geminin 0.017 0.3213 0.3517
Schistosoma mansoni jumonji domain containing protein 0.0151 0.282 0.3086
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0165 0.3117 0.3595
Plasmodium vivax CDK-related protein kinase 6, putative 0.0434 0.8664 1
Echinococcus multilocularis dnaJ subfamily B 0.0457 0.9131 1
Loa Loa (eye worm) hypothetical protein 0.0045 0.0631 0.0718
Trypanosoma brucei glucose transporter 2A 0.0032 0.036 0.6373
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0205 0.3941 0.4501
Onchocerca volvulus Chorion peroxidase homolog 0.0038 0.05 0.0497
Plasmodium vivax histone acetyltransferase GCN5, putative 0.005 0.0737 0.0848
Loa Loa (eye worm) hypothetical protein 0.0031 0.0352 0.0399
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0066 0.1061 0.1159
Trichomonas vaginalis glucose transporter, putative 0.0032 0.036 0.0358
Echinococcus granulosus smad 0.0017 0.0056 0.0059
Leishmania major hypothetical protein, conserved 0.0019 0.0092 0.1593
Brugia malayi Probable ClpP-like protease 0.0076 0.1274 0.1455
Plasmodium falciparum JmjC domain-containing protein, putative 0.0019 0.0092 0.0103
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.2745 0.3004
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0065 0.1046 0.1143
Trypanosoma cruzi metacaspase, putative 0.002 0.0116 0.2028
Loa Loa (eye worm) hypothetical protein 0.014 0.2601 0.297
Loa Loa (eye worm) hypothetical protein 0.0039 0.0501 0.0569
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.005 0.0734 0.2504
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0019 0.0106 0.0396
Toxoplasma gondii histone lysine methyltransferase SET1 0.0069 0.1138 0.2004
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0169 0.0183
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0088 0.0085
Schistosoma mansoni smad1 5 8 and 0.0017 0.0056 0.0059
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Brugia malayi Latrophilin receptor protein 2 0.0065 0.1046 0.1195
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0564 0.0993
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Echinococcus multilocularis Smad4 0.0017 0.0056 0.0059
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0023 0.0177 0.0283
Trypanosoma brucei Metacaspase-4 0.002 0.0116 0.2028
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Echinococcus granulosus phd:f box containing protein 0.0019 0.0092 0.0098
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0031 0.0352 0.0404
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0019 0.0088 0.0085
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0031 0.0352 0.0399
Schistosoma mansoni hypothetical protein 0.017 0.3213 0.3517
Plasmodium falciparum protein kinase 6 0.0434 0.8664 1
Onchocerca volvulus Dual oxidase homolog 0.0038 0.05 0.0497
Loa Loa (eye worm) bromodomain containing protein 0.0022 0.0153 0.0172
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0902 0.1028
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Onchocerca volvulus 0.0075 0.1248 0.1246
Schistosoma mansoni hypothetical protein 0.0065 0.1046 0.1143
Plasmodium falciparum mitogen-activated protein kinase 2 0.0165 0.3117 0.3595
Trypanosoma cruzi hexose transporter, putative 0.0032 0.036 0.6373
Trypanosoma cruzi ISWI complex protein 0.0015 0.0022 0.0352
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0007 0.0005
Mycobacterium ulcerans glutaminase 0.0274 0.5362 1
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Brugia malayi latrophilin 2 splice variant baaae 0.014 0.2601 0.2972
Echinococcus granulosus peroxidasin 0.0038 0.05 0.0544
Trypanosoma cruzi metacaspase, putative 0.002 0.0116 0.2028
Schistosoma mansoni caspase-7 (C14 family) 0.0066 0.1073 0.1172
Leishmania major protein kinase, putative 0.0031 0.0352 0.6225
Loa Loa (eye worm) hypothetical protein 0.0267 0.5223 0.5966
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.036 0.6373
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0116 0.0201
Echinococcus multilocularis survival motor neuron protein 1 0.0267 0.5223 0.5719
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0147 0.2745 0.3004
Brugia malayi hypothetical protein 0.0014 0.0003 0.0003
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0076 0.1274 0.1393
Schistosoma mansoni caspase-7 (C14 family) 0.002 0.0116 0.0125
Brugia malayi CHD4 protein 0.0015 0.0015 0.0017
Echinococcus granulosus jumonji domain containing protein 0.0081 0.1371 0.1499
Plasmodium falciparum calcium-dependent protein kinase 4 0.0031 0.0352 0.0404
Loa Loa (eye worm) hypothetical protein 0.0081 0.1369 0.1561
Loa Loa (eye worm) transcription factor SMAD2 0.0249 0.485 0.5541
Brugia malayi Major Facilitator Superfamily protein 0.0014 0.0003 0.0003
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.1157 0.1265
Trypanosoma brucei THT1 - hexose transporter, putative 0.0032 0.036 0.6373
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0019 0.0092 0.0158
Schistosoma mansoni bromodomain containing protein 0.0069 0.1135 0.124
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.002 0.0119 0.0116
Leishmania major glucose transporter, lmgt2 0.0032 0.036 0.6373
Loa Loa (eye worm) jmjC domain-containing protein 0.012 0.2177 0.2485
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0075 0.1248 0.1364
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.005 0.0734 0.2801
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.019 0.3625 0.3968
Echinococcus multilocularis peroxidasin 0.0038 0.05 0.0544
Trypanosoma brucei glucose transporter, putative 0.0032 0.036 0.6373
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0164 0.3095 0.3387
Brugia malayi glutaminase DH11.1 0.0274 0.5362 0.6127
Entamoeba histolytica protein kinase, putative 0.0031 0.0352 0.0462
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0561 0.0559
Brugia malayi Sugar transporter family protein 0.0102 0.1817 0.2075
Loa Loa (eye worm) animal heme peroxidase 0.0038 0.05 0.0568
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0063 0.1016 0.111
Schistosoma mansoni cpg binding protein 0.0032 0.0368 0.04
Plasmodium vivax SET domain protein, putative 0.0063 0.1016 0.117
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Brugia malayi acetyltransferase, GNAT family protein 0.0164 0.3095 0.3536
Brugia malayi Blistered cuticle protein 3 0.0038 0.05 0.0571
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0902 0.0986
Onchocerca volvulus Peroxidase homolog 0.0038 0.05 0.0497
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.002 0.0116 0.0201
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0095 0.0093
Echinococcus granulosus Smad4 0.0017 0.0056 0.0059
Brugia malayi jmjC domain containing protein 0.0019 0.0092 0.0105
Loa Loa (eye worm) animal heme peroxidase 0.0038 0.05 0.0568
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0501 0.0498
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.2745 0.3004
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0902 0.0986
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0564 1
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Leishmania major glucose transporter, lmgt3 0.0032 0.036 0.6373
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0133 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.036 0.0358
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0031 0.0352 0.0617
Schistosoma mansoni ap endonuclease 0.0019 0.0095 0.0101
Echinococcus multilocularis caspase 0.002 0.0116 0.0125
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0076 0.1274 0.466
Schistosoma mansoni cpg binding protein 0.0036 0.0445 0.0484
Toxoplasma gondii exonuclease III APE 0.0019 0.0095 0.0163
Brugia malayi PHD-finger family protein 0.0058 0.0902 0.1031
Schistosoma mansoni hypothetical protein 0.0019 0.0097 0.0103
Brugia malayi lysyl-tRNA synthetase 0.0023 0.0177 0.0202
Echinococcus granulosus zinc finger protein 0.0025 0.023 0.025
Brugia malayi F/Y-rich N-terminus family protein 0.0033 0.0386 0.0441
Schistosoma mansoni caspase-3 (C14 family) 0.002 0.0116 0.0125
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Schistosoma mansoni glucose transport protein 0.0102 0.1817 0.1987
Echinococcus granulosus peregrin 0.0064 0.1033 0.1129
Trypanosoma cruzi ISWI complex protein 0.0015 0.0022 0.0352
Onchocerca volvulus 0.0046 0.0662 0.066
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0095 0.1648
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Onchocerca volvulus Peroxidase homolog 0.0038 0.05 0.0497
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 0.2372
Loa Loa (eye worm) hypothetical protein 0.0049 0.0708 0.0806
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0095 0.0106
Loa Loa (eye worm) hypothetical protein 0.0042 0.0564 0.0642
Schistosoma mansoni ap endonuclease 0.0019 0.0095 0.0101
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.006 0.0954 0.1042
Brugia malayi Animal haem peroxidase family protein 0.0038 0.05 0.0571
Echinococcus multilocularis GPCR, family 2 0.0065 0.1046 0.1143
Trypanosoma cruzi hexose transporter 0.0032 0.036 0.6373
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0141 0.2612 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Onchocerca volvulus Peroxidasin homolog 0.0038 0.05 0.0497
Brugia malayi hypothetical protein 0.0267 0.5223 0.5967
Schistosoma mansoni glucose transport protein 0.0102 0.1817 0.1987
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0059 0.0061
Schistosoma mansoni survival motor neuron protein 0.0055 0.0831 0.0908
Loa Loa (eye worm) glutaminase 0.0274 0.5362 0.6125
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0018 0.0016
Trichomonas vaginalis glucose transporter, putative 0.0032 0.036 0.0358
Schistosoma mansoni hypothetical protein 0.0065 0.1046 0.1143
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.0019 0.0097 0.0166
Plasmodium vivax lysine--tRNA ligase, putative 0.0023 0.0177 0.0201
Loa Loa (eye worm) hypothetical protein 0.0071 0.1169 0.1333
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0015 0.0015 0.0014
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0065 0.1046 0.1143
Leishmania major metacaspase, putative 0.002 0.0116 0.2028
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0564 0.0615
Schistosoma mansoni protein kinase 0.0031 0.0352 0.0383
Treponema pallidum fructose-bisphosphate aldolase 0.0288 0.5655 1
Loa Loa (eye worm) hypothetical protein 0.0066 0.1073 0.1223
Loa Loa (eye worm) hypothetical protein 0.0031 0.0339 0.0385
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0095 0.0093
Trichomonas vaginalis sugar transporter, putative 0.0032 0.036 0.0358
Brugia malayi jmjC domain containing protein 0.0019 0.0092 0.0105
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0095 0.0107
Schistosoma mansoni Smad4 0.0017 0.0056 0.0059
Onchocerca volvulus 0.0038 0.05 0.0497
Giardia lamblia PHD finger protein 15 0.0058 0.0902 0.1592
Echinococcus granulosus peptidase Clp S14 family 0.005 0.0734 0.0801
Loa Loa (eye worm) animal heme peroxidase 0.0038 0.05 0.0568
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Echinococcus multilocularis smad 0.0017 0.0056 0.0059
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0205 0.3941 0.4503
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Echinococcus granulosus dnaJ subfamily B 0.0457 0.9131 1
Schistosoma mansoni hypothetical protein 0.0065 0.1046 0.1143
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0288 0.5655 0.5654
Entamoeba histolytica hypothetical protein 0.0036 0.045 0.0639
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0095 0.0355
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0564 0.0615
Plasmodium falciparum calcium-dependent protein kinase 2 0.0031 0.0352 0.0404
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0064 0.1087
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Brugia malayi jmjC domain containing protein 0.019 0.3625 0.4142
Plasmodium falciparum calcium-dependent protein kinase 3 0.0031 0.0352 0.0404
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0097 0.168
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0564 0.0844
Schistosoma mansoni cpg binding protein 0.0036 0.0445 0.0484
Brugia malayi jmjC domain containing protein 0.0019 0.0092 0.0105
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0269 0.0266
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.1369 0.1496
Trypanosoma brucei glucose transporter 1E 0.0032 0.036 0.6373
Brugia malayi Heterochromatin protein 1 0.0069 0.1124 0.1284
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Echinococcus granulosus chromobox protein 1 0.0069 0.1124 0.1228
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0019 0.0092 0.0158
Brugia malayi hypothetical protein 0.0036 0.045 0.0514
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0019 0.0092 0.1593
Loa Loa (eye worm) hypothetical protein 0.0205 0.3941 0.4501
Giardia lamblia Fructose-bisphosphate aldolase 0.0288 0.5655 1
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0031 0.0339 0.0439
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0564 0.0562
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0269 0.0266
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.002 0.0116 0.0125
Schistosoma mansoni zinc finger protein 0.0015 0.0022 0.0022
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0056 0.0059
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0095 0.0101
Schistosoma mansoni peptidase Clp (S14 family) 0.0076 0.1274 0.1393
Loa Loa (eye worm) hypothetical protein 0.0038 0.05 0.0568
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.0019 0.0097 0.168
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0564 0.0615
Echinococcus granulosus survival motor neuron protein 1 0.0267 0.5223 0.5719
Entamoeba histolytica acetyltransferase, GNAT family 0.0044 0.0606 0.0919
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0147 0.2745 0.3004
Toxoplasma gondii hypothetical protein 0.0026 0.0246 0.043
Loa Loa (eye worm) CXXC zinc finger family protein 0.0032 0.0368 0.0417
Trypanosoma cruzi hexose transporter, putative 0.0032 0.036 0.6373
Brugia malayi Pre-SET motif family protein 0.0063 0.1016 0.1161
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0147 0.2745 0.3004
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0177 0.0191
Brugia malayi MH2 domain containing protein 0.0017 0.0056 0.0064
Onchocerca volvulus 0.0038 0.05 0.0497
Trichomonas vaginalis CAMK family protein kinase 0.0031 0.0352 0.035
Schistosoma mansoni glucose transport protein 0.0102 0.1817 0.1987
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0081 0.1369 0.1496
Trichomonas vaginalis conserved hypothetical protein 0.0032 0.036 0.0358
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0092 0.0102
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0031 0.0352 0.0383
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0031 0.0352 0.0402
Echinococcus granulosus lysyl tRNA synthetase 0.0023 0.0177 0.0191
Echinococcus granulosus apoptotic protease activating factor 1 0.0046 0.0662 0.0722
Echinococcus granulosus GPCR family 2 0.0065 0.1046 0.1143
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0564 0.0615
Brugia malayi Pre-SET motif family protein 0.0438 0.8752 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0019 0.0088 0.0085
Brugia malayi Cam kinase protein 1 0.0031 0.0352 0.0402
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.002 0.0116 0.0114
Loa Loa (eye worm) blistered cuticle protein 3 0.0038 0.05 0.0568
Schistosoma mansoni hypothetical protein 0.0102 0.1817 0.1987
Trypanosoma cruzi metacaspase 5, putative 0.002 0.0116 0.2028
Echinococcus granulosus General substrate transporter 0.0088 0.152 0.1662
Echinococcus granulosus histone acetyltransferase KAT2B 0.005 0.0737 0.0804
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.045 0.049
Brugia malayi major facilitator superfamily protein 0.0014 0.0003 0.0003
Trichomonas vaginalis glutaminase, putative 0.0274 0.5362 0.5361
Trichomonas vaginalis chromobox protein, putative 0.0069 0.1124 0.1122
Schistosoma mansoni glutaminase 0.0274 0.5362 0.5871
Echinococcus granulosus lysine specific demethylase 6a 0.0019 0.0092 0.0098
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0102 0.1817 0.1987
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0076 0.1274 0.2243
Schistosoma mansoni lysyl-tRNA synthetase 0.0023 0.0177 0.0191
Trypanosoma brucei ISWI complex protein 0.0015 0.0022 0.0352
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0036 0.0444 0.7861
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0026 0.0246 0.0281
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0076 0.1274 0.1468
Loa Loa (eye worm) hypothetical protein 0.0099 0.1757 0.2006
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0095 0.0101
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0116 0.0114
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.1154 0.1262
Schistosoma mansoni hypothetical protein 0.0021 0.0133 0.0143
Trichomonas vaginalis bromodomain-containing protein, putative 0.005 0.0737 0.0735
Loa Loa (eye worm) jmjC domain-containing protein 0.0019 0.0092 0.0102
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0023 0.0177 0.3105
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0164 0.3095 0.3387
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0449 0.0489
Loa Loa (eye worm) hypothetical protein 0.0019 0.0092 0.0102
Entamoeba histolytica hypothetical protein 0.0036 0.045 0.0639
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0147 0.2745 0.3136
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0031 0.0339 0.0369
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.005 0.0737 0.1296
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0076 0.1274 1
Schistosoma mansoni protein kinase 0.0031 0.0352 0.0383
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0031 0.0339 0.0369
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.002 0.0116 0.0125

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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