Detailed information for compound 58617

Basic information

Technical information
  • TDR Targets ID: 58617
  • Name: 4,5-diacetyloxy-9,10-dioxoanthracene-2-carbox ylic acid
  • MW: 368.294 | Formula: C19H12O8
  • H donors: 1 H acceptors: 6 LogP: 1.9 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC(=O)Oc1cc(cc2c1C(=O)c1c(C2=O)cccc1OC(=O)C)C(=O)O
  • InChi: 1S/C19H12O8/c1-8(20)26-13-5-3-4-11-15(13)18(23)16-12(17(11)22)6-10(19(24)25)7-14(16)27-9(2)21/h3-7H,1-2H3,(H,24,25)
  • InChiKey: TYNLGDBUJLVSMA-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • 4,5-diacetoxy-9,10-dioxo-anthracene-2-carboxylic acid
  • 4,5-diacetoxy-9,10-dioxo-2-anthracenecarboxylic acid
  • 4,5-diacetyloxy-9,10-dioxo-anthracene-2-carboxylic acid
  • 4,5-diacetoxy-9,10-diketo-anthracene-2-carboxylic acid
  • diacetylrhein
  • 13739-02-1
  • KW-4800
  • 1,8-Diacetoxyanthraquinone-3-carboxylic acid
  • 2-ANTHROIC ACID, 9,10-DIHYDRO-4,5-DIHYDROXY-9,10-DIOXO-, DIACETATE
  • 2-Anthracenecarboxylic acid, 4,5-bis(acetyloxy)-9,10-dihydro-9,10-dioxo- (9CI)
  • 3-10-00-04790 (Beilstein Handbook Reference)
  • 4,5-Diacetoxy-9,10-dihydro-9,10-dioxo-2-anthrylcarbonsaeure
  • 4,5-Diacetylrhein
  • 9,10-Dihydro-4,5-diacetoxy-9,10-2-anthracenecarboxylic acid
  • 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroic acid diacetate
  • 9,10-Dihydro-4,5-dihydroxy-9,10-dioxo-2-anthroic acid, diacetate
  • Artrodar
  • BRN 2184909
  • Diacerein
  • Diacerein [INN]
  • Diacereina [Spanish]
  • Diacereine [French]
  • Diacereinum [Latin]
  • Diacerhein
  • EINECS 237-310-2
  • Fisiodar
  • Rhein, diacetate (6CI)
  • SF-277
  • SMR000058958
  • Spectrum2_000823
  • NCGC00022114-03
  • KBioGR_001591
  • Spectrum_001876
  • SpecPlus_000643
  • SPECTRUM1502010
  • 1,8-DIACETOXY-3-CARBOXYANTHRAQUINONE
  • KBio3_001974
  • D9302_SIGMA
  • KBio1_001683
  • KBioSS_002400
  • Spectrum5_001819
  • Spectrum3_000937
  • SPBio_000745
  • MLS000028577
  • KBio2_002395
  • KBio2_004963
  • KBio2_007531
  • BB_SC-5077
  • Spectrum4_001036
  • DivK1c_006739

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references
Homo sapiens polymerase (DNA directed), eta Starlite/ChEMBL No references
Homo sapiens caspase 3, apoptosis-related cysteine peptidase Starlite/ChEMBL No references
Homo sapiens heat shock protein 90kDa alpha (cytosolic), class A member 1 No references
Homo sapiens EYA transcriptional coactivator and phosphatase 2 Starlite/ChEMBL No references
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens euchromatic histone-lysine N-methyltransferase 2 Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Homo sapiens lysine (K)-specific methyltransferase 2A Starlite/ChEMBL No references
Homo sapiens caspase 7, apoptosis-related cysteine peptidase Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens nuclear factor, erythroid 2-like 2 Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references
Caenorhabditis elegans Protein GLD-1 Starlite/ChEMBL No references
Homo sapiens multiple endocrine neoplasia I No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens heat shock protein 90kDa alpha (cytosolic), class B member 1 Starlite/ChEMBL No references
Homo sapiens peptidylprolyl cis/trans isomerase, NIMA-interacting 1 Starlite/ChEMBL No references
Homo sapiens isocitrate dehydrogenase 1 (NADP+), soluble Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Plasmodium knowlesi isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium knowlesi endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K04397 caspase 7, apoptosis-related cysteine protease, putative Get druggable targets OG5_130238 All targets in OG5_130238
Trypanosoma brucei isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni hypothetical protein Get druggable targets OG5_133913 All targets in OG5_133913
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) Get druggable targets OG5_126623 All targets in OG5_126623
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni eyes absent homolog Get druggable targets OG5_129664 All targets in OG5_129664
Leishmania infantum lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Cryptosporidium parvum Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum Isocitrate dehydrogenase-like protein, related Get druggable targets OG5_127057 All targets in OG5_127057
Plasmodium vivax heat shock protein 86, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium yoelii putative heat shock protein 81-2 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Echinococcus granulosus heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Giardia lamblia Grp94/Hsp90 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus granulosus heat shock protein heat shock protein 90 alpha Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Leishmania braziliensis heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei gambiense peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Neospora caninum peptidyl-prolyl cis-trans isomerase NIMA- interacting 1, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania braziliensis DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum IPR003367,Thrombospondin type 3 repeat;IPR002048,Calcium-binding EF-hand,domain-containing Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Menin, putative Get druggable targets OG5_133913 All targets in OG5_133913
Plasmodium berghei isocitrate dehydrogenase [NADP], mitochondrial, putative Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium yoelii heat shock 90 kDa protein homolog Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K04079 molecular chaperone HtpG, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania braziliensis isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans N terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma brucei Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum hypothetical protein Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum Pc21g17280 protein, related Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma cruzi Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Cryptosporidium parvum DinB/family X-type DNA polymerase Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) pre-SET domain-containing protein family protein Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni DNA polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium falciparum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania donovani heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium ulcerans heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi tumor suppressor. Get druggable targets OG5_170288 All targets in OG5_170288
Loa Loa (eye worm) heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trichomonas vaginalis conserved hypothetical protein Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 Get druggable targets OG5_128367 All targets in OG5_128367
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Neospora caninum HSP90, related Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans Mitochondrial NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Loa Loa (eye worm) endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans C terminus of cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni caspase-3 (C14 family) Get druggable targets OG5_130238 All targets in OG5_130238
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans cytosolic NADP-specific isocitrate dehydrogenase. Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni rotamase Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma congolense peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Onchocerca volvulus Get druggable targets OG5_131470 All targets in OG5_131470
Schistosoma japonicum Heat shock protein HSP 90-alpha, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma mansoni NADP-specific isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase Get druggable targets OG5_130238 All targets in OG5_130238
Echinococcus granulosus caspase 3 Get druggable targets OG5_130238 All targets in OG5_130238
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis set domain proteins, putative Get druggable targets OG5_131470 All targets in OG5_131470
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis caspase Get druggable targets OG5_130238 All targets in OG5_130238
Leishmania infantum isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania donovani heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum HSP90-like protein, related Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana Get druggable targets OG5_128521 All targets in OG5_128521
Toxoplasma gondii peptidylprolyl isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus dnaJ subfamily B Get druggable targets OG5_133913 All targets in OG5_133913
Brugia malayi Isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Babesia bovis isocitrate dehydrogenase, NADP-dependent family protein Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis caspase 3 Get druggable targets OG5_130238 All targets in OG5_130238
Brugia malayi isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania infantum DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trichomonas vaginalis rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Brugia malayi ImpB/MucB/SamB family protein Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent, putative Get druggable targets OG5_127057 All targets in OG5_127057
Treponema pallidum heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans hypothetical protein Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Trypanosoma cruzi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) tumor suppressor Get druggable targets OG5_170288 All targets in OG5_170288
Brugia malayi Endoplasmin precursor Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Trypanosoma congolense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium knowlesi heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K03509 DNA polymerase eta subunit, putative Get druggable targets OG5_128521 All targets in OG5_128521
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium vivax endoplasmin, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Schistosoma japonicum ko:K01104 protein-tyrosine phosphatase [EC3.1.3.48], putative Get druggable targets OG5_129664 All targets in OG5_129664
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Entamoeba histolytica heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus endoplasmin Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense heat shock protein 83,heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K00031 isocitrate dehydrogenase [EC1.1.1.42], putative Get druggable targets OG5_127057 All targets in OG5_127057
Theileria parva heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Plasmodium yoelii heat shock protein 90 Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus multilocularis dna polymerase eta Get druggable targets OG5_128521 All targets in OG5_128521
Leishmania infantum heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Neospora caninum Multidomain chromatinic protein with the following architecture: 3x PHD-bromo-3xPHD-SET domain and associated cysteine cluster a Get druggable targets OG5_130642 All targets in OG5_130642
Theileria parva peptidyl-prolyl cis-trans isomerase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma brucei gambiense Heat shock protein 83, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Brugia malayi Pre-SET motif family protein Get druggable targets OG5_131470 All targets in OG5_131470
Candida albicans peptidylprolyl cis/trans isomerase isolated by functional complementation of S. cerevisiae ESS1 (YJR017C) which interacts with t Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania donovani peptidyl-prolyl cis-trans isomerase/rotamase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania infantum peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative Get druggable targets OG5_128367 All targets in OG5_128367
Schistosoma mansoni caspase-7 (C14 family) Get druggable targets OG5_130238 All targets in OG5_130238
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K09188 myeloid/lymphoid or mixed-lineage leukemia protein 3, putative Get druggable targets OG5_130642 All targets in OG5_130642
Plasmodium yoelii isocitrate dehydrogenase, NADP-dependent Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania braziliensis lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus caspase Get druggable targets OG5_130238 All targets in OG5_130238
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Theileria parva isocitrate dehydrogenase (NADP+), putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma japonicum ko:K02187 caspase 3, apoptosis-related cysteine protease, putative Get druggable targets OG5_130238 All targets in OG5_130238
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania mexicana heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative Get druggable targets OG5_126623 All targets in OG5_126623
Candida albicans similar to S. cerevisiae DNA polymerase pol-eta, involved in the bypass of distorted DNA lesions Get druggable targets OG5_128521 All targets in OG5_128521
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Heat shock protein HSP 90-beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma japonicum ko:K09487 heat shock protein 90kDa beta, putative Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania mexicana isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128521 All targets in OG5_128521
Giardia lamblia Heat shock protein HSP 90-alpha Get druggable targets OG5_126623 All targets in OG5_126623
Plasmodium berghei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Toxoplasma gondii heat shock protein HSP90 Get druggable targets OG5_126623 All targets in OG5_126623
Babesia bovis hsp90 protein Get druggable targets OG5_126623 All targets in OG5_126623
Echinococcus granulosus expressed protein Get druggable targets OG5_128367 All targets in OG5_128367
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma congolense isocitrate dehydrogenase, putative Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei gambiense isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Schistosoma mansoni mixed-lineage leukemia protein mll Get druggable targets OG5_130642 All targets in OG5_130642
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_129664 All targets in OG5_129664
Trypanosoma congolense heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trichomonas vaginalis heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein 90, putative Get druggable targets OG5_126623 All targets in OG5_126623
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) Get druggable targets OG5_127057 All targets in OG5_127057
Toxoplasma gondii histone lysine methyltransferase SET1 Get druggable targets OG5_130642 All targets in OG5_130642
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania major heat shock protein 83-1 Get druggable targets OG5_126623 All targets in OG5_126623
Schistosoma mansoni heat shock protein Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma brucei heat shock protein, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi heat shock protein 85, putative Get druggable targets OG5_126623 All targets in OG5_126623
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase Get druggable targets OG5_128367 All targets in OG5_128367
Trypanosoma cruzi DNA polymerase eta, putative Get druggable targets OG5_128521 All targets in OG5_128521
Toxoplasma gondii isocitrate dehydrogenase Get druggable targets OG5_127057 All targets in OG5_127057
Leishmania donovani isocitrate dehydrogenase [NADP], mitochondrial precursor, putative Get druggable targets OG5_127057 All targets in OG5_127057
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Cryptosporidium hominis heat shock protein 83 Get druggable targets OG5_126623 All targets in OG5_126623
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi Cell death protein 3 precursor caspase 7, apoptosis-related cysteine peptidase 303 aa 256 aa 37.1 %
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Leishmania major peptidyl-prolyl cis-trans isomerase, putative peptidylprolyl cis/trans isomerase, NIMA-interacting 1 163 aa 133 aa 27.8 %
Plasmodium falciparum heat shock protein 90, putative heat shock protein 90kDa alpha (cytosolic), class B member 1 724 aa 725 aa 35.6 %
Brugia malayi Cell death protein 3 precursor caspase 3, apoptosis-related cysteine peptidase 277 aa 253 aa 38.7 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0064 0.0655 0.0655
Plasmodium falciparum heat shock protein 90, putative 0.0032 0.0267 0.3215
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0016 0.007 0.0846
Loa Loa (eye worm) hypothetical protein 0.006 0.0602 0.0605
Trypanosoma brucei metacaspase 5, putative 0.0064 0.0655 0.7892
Schistosoma mansoni heat shock protein 0.0032 0.0267 0.0267
Trypanosoma brucei heat shock protein, putative 0.0078 0.083 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0828 0.9935 0.9935
Brugia malayi sulfakinin receptor protein 0.0828 0.9935 1
Onchocerca volvulus 0.0828 0.9935 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0828 0.9935 1
Brugia malayi Isocitrate dehydrogenase 0.0019 0.0108 0.0108
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Onchocerca volvulus 0.0828 0.9935 1
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0354 0.4273
Brugia malayi hypothetical protein 0.0828 0.9935 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0828 0.9935 0.9935
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0016 0.007 0.1105
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0032 0.0267 0.0269
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0024 0.0024
Giardia lamblia DINP protein human, muc B family 0.0023 0.0159 0.1918
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Loa Loa (eye worm) histone methyltransferase 0.0012 0.0022 0.0023
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0024 0.0024
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0024 0.0024
Echinococcus granulosus dna polymerase kappa 0.0023 0.0159 0.0159
Onchocerca volvulus 0.0035 0.0297 0.0299
Echinococcus granulosus rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Brugia malayi hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni hypothetical protein 0.0828 0.9935 0.9935
Trichomonas vaginalis rotamase, putative 0.004 0.0366 0.1089
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0366 0.1089
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0016 0.007 0.0741
Leishmania major metacaspase, putative 0.0064 0.0655 0.7892
Echinococcus granulosus rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0063 0.0635 0.7659
Mycobacterium leprae Probable two component sensor kinase MprB 0.0016 0.007 0.1105
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0012 0.0024 0.0024
Echinococcus granulosus tumor protein p63 0.0408 0.4833 0.4833
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0016 0.0067 0.0067
Giardia lamblia Pms1-like protein 0.0016 0.007 0.0846
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0024 0.0024
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0012 0.0024 0.0024
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0828 0.9935 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0828 0.9935 0.9935
Mycobacterium tuberculosis Conserved protein 0.0016 0.007 0.1105
Schistosoma mansoni retinoic acid receptor RXR 0.0012 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0024 0.0024
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0828 0.9935 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0012 0.0024 0.0024
Trypanosoma brucei heat shock protein, putative 0.0078 0.083 1
Brugia malayi Serotonin receptor 0.0828 0.9935 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0016 0.007 0.1105
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0828 0.9935 0.9935
Echinococcus granulosus peptide allatostatin:somatostatin 0.0828 0.9935 0.9935
Onchocerca volvulus 0.0828 0.9935 1
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) isocitrate dehydrogenase 0.0019 0.0108 0.0108
Brugia malayi F/Y-rich N-terminus family protein 0.0012 0.0021 0.0021
Echinococcus granulosus alpha 1A adrenergic receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0043 0.0404 0.0404
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni biogenic amine receptor 0.0828 0.9935 0.9935
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0016 0.007 0.0846
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0828 0.9935 0.9935
Schistosoma mansoni neuropeptide receptor 0.0828 0.9935 0.9935
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Onchocerca volvulus 0.0828 0.9935 1
Echinococcus granulosus caspase 2 0.0064 0.0655 0.0655
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Brugia malayi neuropeptide F receptor 0.0828 0.9935 1
Schistosoma mansoni neuropeptide receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0012 0.0024 0.0024
Brugia malayi hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Schistosoma mansoni opsin-like receptor 0.0828 0.9935 0.9935
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Echinococcus multilocularis survival motor neuron protein 1 0.0286 0.3345 0.3345
Toxoplasma gondii histone lysine methyltransferase SET1 0.0067 0.069 0.8321
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni DNA polymerase eta 0.0054 0.0533 0.0533
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0037 0.0323 0.0323
Trypanosoma cruzi metacaspase 5, putative 0.0064 0.0655 0.7892
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0828 0.9935 0.9935
Giardia lamblia Heat shock protein HSP 90-alpha 0.0078 0.083 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0828 0.9935 1
Echinococcus granulosus lamin 0.0033 0.0272 0.0272
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Onchocerca volvulus 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0016 0.007 0.1105
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0025 0.0301
Mycobacterium tuberculosis Possible two component sensor kinase 0.0016 0.007 0.1105
Schistosoma mansoni transcription factor LCR-F1 0.0043 0.0404 0.0404
Brugia malayi isocitrate dehydrogenase 0.0019 0.0108 0.0108
Brugia malayi CXXC zinc finger family protein 0.0035 0.0297 0.0299
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0012 0.0024 0.0024
Echinococcus multilocularis serotonin receptor 0.0828 0.9935 0.9935
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0019 0.0108 0.1299
Echinococcus multilocularis dnaJ subfamily B 0.0494 0.5877 0.5877
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Brugia malayi RE15519p 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Entamoeba histolytica 90 kDa heat shock protein, putative 0.0032 0.0267 0.3215
Trypanosoma cruzi heat shock protein 90, putative 0.0063 0.0635 0.7659
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0159 0.1918
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0016 0.007 0.0209
Echinococcus granulosus rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0016 0.007 0.1105
Echinococcus multilocularis allatostatin A receptor 0.0828 0.9935 0.9935
Schistosoma mansoni coup transcription factor 0.0012 0.0024 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0106 0.1169 0.1176
Brugia malayi hypothetical protein 0.0106 0.1169 0.1176
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0071 0.0859
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Echinococcus granulosus 7TM GPCR rhodopsin 0.0828 0.9935 0.9935
Leishmania major heat shock protein, putative 0.0032 0.0267 0.3215
Plasmodium vivax heat shock protein, putative 0.0032 0.0267 0.3215
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0828 0.9935 0.9935
Schistosoma mansoni steroid hormone receptor ad4bp 0.0012 0.0024 0.0024
Mycobacterium ulcerans two component sensor kinase MprB 0.0016 0.007 0.1105
Brugia malayi nuclear hormone receptor 0.0012 0.0024 0.0024
Trypanosoma cruzi heat shock protein 85, putative 0.0078 0.083 1
Echinococcus granulosus expressed protein 0.004 0.0366 0.0366
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Leishmania major developmentally regulated phosphoprotein-like protein 0.0016 0.007 0.0846
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0016 0.007 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0655 0.1949
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Brugia malayi AKH receptor 0.0828 0.9935 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0106 0.1169 0.1176
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0039 0.0354 0.4273
Brugia malayi Dopamine receptor protein 1 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Entamoeba histolytica DNA topoisomerase II, putative 0.0016 0.007 0.0846
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0016 0.007 0.007
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Echinococcus multilocularis neuropeptides capa receptor 0.0828 0.9935 0.9935
Schistosoma mansoni hypothetical protein 0.0033 0.0275 0.0275
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0064 0.0655 0.0659
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0828 0.9935 0.9935
Trypanosoma brucei metacaspase MCA2 0.0064 0.0655 0.7892
Entamoeba histolytica heat shock protein 90, putative 0.0078 0.083 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0828 0.9935 0.9935
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0828 0.9935 1
Trypanosoma brucei unspecified product 0.0016 0.0071 0.0859
Entamoeba histolytica hypothetical protein 0.0043 0.0404 0.4867
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0012 0.0024 0.0024
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0016 0.007 0.0846
Echinococcus granulosus intermediate filament protein 0.0033 0.0272 0.0272
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0012 0.0024 0.0024
Echinococcus multilocularis somatostatin receptor 0.0828 0.9935 0.9935
Brugia malayi hypothetical protein 0.0043 0.0404 0.0406
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0016 0.007 0.1105
Loa Loa (eye worm) hypothetical protein 0.0054 0.0533 0.0536
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0071
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0828 0.9935 0.9935
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0019 0.0108 0.1299
Echinococcus multilocularis lamin 0.0033 0.0272 0.0272
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0039 0.0354 0.4273
Schistosoma mansoni amine GPCR 0.0828 0.9935 0.9935
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0828 0.9935 0.9935
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0012 0.0024 0.0024
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0828 0.9935 0.9935
Echinococcus granulosus endoplasmin 0.0063 0.0635 0.0635
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0828 0.9935 0.9935
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0159 0.2504
Chlamydia trachomatis DNA gyrase subunit B 0.0016 0.007 1
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0016 0.007 0.0846
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0655 0.1949
Echinococcus granulosus FTZ F1 alpha 0.0012 0.0024 0.0024
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0071 0.0859
Schistosoma mansoni caspase-7 (C14 family) 0.0064 0.0655 0.0655
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0108 0.1299
Echinococcus multilocularis rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Schistosoma mansoni heat shock protein 0.0078 0.083 0.083
Echinococcus granulosus dna polymerase eta 0.0054 0.0533 0.0533
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0828 0.9935 0.9935
Schistosoma mansoni lamin 0.0033 0.0272 0.0272
Echinococcus granulosus protein quaking 0.0033 0.0275 0.0275
Brugia malayi G-protein coupled receptor 0.0828 0.9935 1
Leishmania major DNA topoisomerase ii 0.0016 0.007 0.0846
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni amine GPCR 0.0828 0.9935 0.9935
Schistosoma mansoni amine GPCR 0.0828 0.9935 0.9935
Schistosoma mansoni alpha-1 adrenergic receptor 0.0828 0.9935 0.9935
Schistosoma mansoni RAR-like nuclear receptor 0.0012 0.0024 0.0024
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0064 0.0655 0.7892
Echinococcus granulosus caspase 3 0.0176 0.201 0.201
Echinococcus granulosus caspase 0.024 0.2789 0.2789
Trypanosoma brucei Heat shock protein 83, putative 0.0078 0.083 1
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0016 0.007 0.0846
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0012 0.0025 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0655 0.1949
Trypanosoma cruzi metacaspase, putative 0.0064 0.0655 0.7892
Trypanosoma brucei DNA polymerase kappa, putative 0.0016 0.0071 0.0859
Plasmodium vivax metacaspase 1, putative 0.0064 0.0655 0.7892
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Leishmania major hypothetical protein, conserved 0.0016 0.007 0.0846
Echinococcus granulosus g protein coupled receptor 0.0828 0.9935 0.9935
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Toxoplasma gondii DNA topoisomerase 2, putative 0.0016 0.007 0.0846
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0108 0.1299
Schistosoma mansoni terminal deoxycytidyl transferase 0.0023 0.0159 0.0159
Brugia malayi steroid hormone receptor 0.0012 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Plasmodium falciparum metacaspase-like protein 0.0064 0.0655 0.7892
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0075 0.0786 0.0786
Brugia malayi nuclear receptor NHR-88 0.0012 0.0024 0.0024
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0016 0.007 0.1105
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Schistosoma mansoni endoplasmin 0.0078 0.083 0.083
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0019 0.0108 0.1299
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0828 0.9935 1
Brugia malayi hypothetical protein 0.0828 0.9935 1
Echinococcus granulosus tm gpcr rhodopsin 0.0828 0.9935 0.9935
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0012 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Plasmodium falciparum heat shock protein 90, putative 0.0032 0.0267 0.3215
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0038 0.0338 0.4069
Brugia malayi hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0272 0.0273
Brugia malayi tumor suppressor. 0.0388 0.4594 0.4624
Brugia malayi Tachykinin-like peptides receptor 99D 0.0828 0.9935 1
Loa Loa (eye worm) neuropeptide F receptor 0.0828 0.9935 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0828 0.9935 0.9935
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0828 0.9935 0.9935
Brugia malayi G-protein coupled receptor 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus granulosus caspase 8 0.0064 0.0655 0.0655
Plasmodium vivax hypothetical protein, conserved 0.0016 0.007 0.0846
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0159 0.1918
Echinococcus multilocularis heat shock protein 0.0078 0.083 0.083
Echinococcus multilocularis dna polymerase eta 0.0054 0.0533 0.0533
Plasmodium vivax DNA topoisomerase II, putative 0.0016 0.007 0.0846
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0016 0.007 0.1105
Trypanosoma brucei DNA polymerase eta, putative 0.0054 0.0533 0.6422
Schistosoma mansoni microtubule-associated protein tau 0.0833 1 1
Schistosoma mansoni DNA topoisomerase II 0.0016 0.007 0.007
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Schistosoma mansoni amine GPCR 0.0828 0.9935 0.9935
Echinococcus multilocularis lamin dm0 0.0033 0.0272 0.0272
Brugia malayi ImpB/MucB/SamB family protein 0.0054 0.0533 0.0536
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0016 0.007 0.0209
Schistosoma mansoni neuropeptide F-like receptor 0.0828 0.9935 0.9935
Schistosoma mansoni caspase-7 (C14 family) 0.024 0.2789 0.2789
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Brugia malayi Cell death protein 3 precursor 0.0064 0.0655 0.0659
Echinococcus granulosus g protein coupled receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis g protein coupled receptor 0.0828 0.9935 0.9935
Schistosoma mansoni neuropeptide receptor 0.0828 0.9935 0.9935
Schistosoma mansoni heat shock protein 0.0078 0.083 0.083
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0019 0.0108 0.0108
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0012 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Onchocerca volvulus 0.0828 0.9935 1
Echinococcus multilocularis protein quaking 0.0033 0.0275 0.0275
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0828 0.9935 0.9935
Schistosoma mansoni histamine h1 receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis heat shock protein 90 0.0078 0.083 0.083
Echinococcus granulosus orexin receptor type 2 0.0828 0.9935 0.9935
Brugia malayi Probable DNA topoisomerase II 0.0016 0.007 0.0071
Schistosoma mansoni amine GPCR 0.0828 0.9935 0.9935
Onchocerca volvulus 0.0828 0.9935 1
Schistosoma mansoni cpg binding protein 0.0037 0.0321 0.0321
Schistosoma mansoni neuropeptide f receptor 76f 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus multilocularis fmrfamide receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) TYRA-2 protein 0.0828 0.9935 1
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0016 0.007 0.1105
Echinococcus granulosus somatostatin receptor 0.0828 0.9935 0.9935
Trypanosoma cruzi Heat shock protein 83, putative 0.0078 0.083 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Onchocerca volvulus Bile acid receptor homolog 0.0012 0.0024 0.0024
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0828 0.9935 0.9935
Brugia malayi follicle stimulating hormone receptor 0.0828 0.9935 1
Brugia malayi putative neuropeptide receptor 0.0828 0.9935 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0828 0.9935 0.9935
Mycobacterium tuberculosis Conserved hypothetical protein 0.0023 0.0159 0.2504
Onchocerca volvulus 0.0828 0.9935 1
Brugia malayi Serotonin receptor 0.0828 0.9935 1
Echinococcus granulosus dro:myosuppressin receptor 0.0828 0.9935 0.9935
Onchocerca volvulus 0.0828 0.9935 1
Brugia malayi Pre-SET motif family protein 0.0037 0.0323 0.0325
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Trypanosoma brucei heat shock protein, putative 0.0078 0.083 1
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0016 0.007 0.0209
Brugia malayi GnHR receptor homolog 0.0828 0.9935 1
Plasmodium vivax DNA gyrase subunit B, putative 0.0016 0.007 0.0846
Loa Loa (eye worm) heat shock protein 75 0.0032 0.0267 0.0269
Echinococcus multilocularis neuropeptide s receptor 0.0828 0.9935 0.9935
Brugia malayi Dopamine receptor protein 2 0.0828 0.9935 1
Trypanosoma brucei unspecified product 0.0023 0.0159 0.1918
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0024 0.0024
Onchocerca volvulus 0.0287 0.336 0.3382
Echinococcus multilocularis rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Brugia malayi photoreceptor-specific nuclear receptor 0.0012 0.0024 0.0024
Schistosoma mansoni caspase-3 (C14 family) 0.024 0.2789 0.2789
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Brugia malayi intermediate filament protein 0.0033 0.0272 0.0273
Schistosoma mansoni biogenic amine (5HT) receptor 0.0828 0.9935 0.9935
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0016 0.007 0.007
Echinococcus granulosus histone lysine methyltransferase setb 0.0037 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0108 0.1299
Loa Loa (eye worm) G-protein coupled receptor 0.0828 0.9935 1
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0012 0.0024 0.0024
Plasmodium vivax hypothetical protein, conserved 0.0064 0.0655 0.7892
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.0655 0.0659
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus multilocularis fmrfamide receptor 0.0828 0.9935 0.9935
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.024 0.2789 0.2789
Brugia malayi G protein-coupled receptor 0.0828 0.9935 1
Schistosoma mansoni intermediate filament proteins 0.0033 0.0272 0.0272
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0016 0.007 0.007
Trypanosoma brucei Metacaspase-4 0.0064 0.0655 0.7892
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0828 0.9935 1
Plasmodium falciparum DNA topoisomerase 2 0.0016 0.007 0.0846
Echinococcus multilocularis isocitrate dehydrogenase 0.0019 0.0108 0.0108
Echinococcus multilocularis microtubule associated protein 2 0.0833 1 1
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0019 0.0108 0.1299
Mycobacterium ulcerans heat shock protein 90 0.0063 0.0635 1
Toxoplasma gondii PPIC-type PPIASE domain-containing protein 0.0012 0.0025 0.0301
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0016 0.007 0.1105
Schistosoma mansoni survival motor neuron protein 0.0058 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0033 0.0272 0.0273
Schistosoma mansoni neuropeptide F-like receptor 0.0828 0.9935 0.9935
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0016 0.007 0.0846
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Echinococcus granulosus neuropeptide receptor 0.0828 0.9935 0.9935
Trypanosoma brucei DNA polymerase IV, putative 0.0023 0.0159 0.1918
Schistosoma mansoni rotamase 0.004 0.0366 0.0366
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0016 0.007 0.1105
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0012 0.0024 0.0024
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0828 0.9935 0.9935
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Brugia malayi Dopamine receptor 0.0828 0.9935 1
Trypanosoma cruzi heat shock protein 90, putative 0.0046 0.0439 0.529
Plasmodium vivax endoplasmin, putative 0.0078 0.083 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0012 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0058 0.0584 0.0584
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0024 0.0024
Mycobacterium leprae Probable two-component sensor kinase 0.0016 0.007 0.1105
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0016 0.007 0.0846
Trichomonas vaginalis heat shock protein, putative 0.0048 0.0461 0.1372
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0012 0.0024 0.0024
Echinococcus granulosus fmrfamide receptor 0.0828 0.9935 0.9935
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0016 0.007 0.1105
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0063 0.0635 1
Trypanosoma brucei metacaspase MCA3 0.0064 0.0655 0.7892
Trichomonas vaginalis receptor histidine kinase, putative 0.0016 0.007 0.0209
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0016 0.007 0.0846
Echinococcus multilocularis heat shock protein 90 0.0063 0.0635 0.0635
Trypanosoma brucei heat shock protein, putative 0.0078 0.083 1
Echinococcus granulosus heat shock protein 90 0.0063 0.0635 0.0635
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0012 0.0024 0.0024
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0016 0.007 1
Trypanosoma cruzi heat shock protein 90, putative 0.0078 0.083 1
Mycobacterium ulcerans two component regulator - sensor kinase 0.0016 0.007 0.1105
Leishmania major DNA polymerase eta, putative 0.0054 0.0533 0.6422
Echinococcus granulosus neuropeptide s receptor 0.0828 0.9935 0.9935
Trypanosoma brucei heat shock protein 90, putative 0.0078 0.083 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0828 0.9935 1
Trichomonas vaginalis heat shock protein, putative 0.0078 0.083 0.2469
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0019 0.0108 0.0108
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0828 0.9935 1
Loa Loa (eye worm) G-protein coupled receptor 0.0828 0.9935 1
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.0063 0.0635 1
Loa Loa (eye worm) tumor suppressor 0.0388 0.4594 0.4624
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0016 0.007 0.0846
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0016 0.007 0.1105
Echinococcus granulosus heat shock protein 0.0078 0.083 0.083
Trichomonas vaginalis endoplasmin, putative 0.0048 0.0461 0.1372
Schistosoma mansoni biogenic amine (5HT) receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis FTZ F1 alpha 0.0012 0.0024 0.0024
Echinococcus multilocularis orexin receptor type 2 0.0828 0.9935 0.9935
Brugia malayi Steroid receptor seven-up type 2 0.0012 0.0024 0.0024
Echinococcus multilocularis neuropeptide Y receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) CXXC zinc finger family protein 0.0035 0.0297 0.0299
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0012 0.0024 0.0024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0323 0.0323
Onchocerca volvulus 0.0828 0.9935 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0012 0.0024 0.0024
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0828 0.9935 0.9935
Toxoplasma gondii heat shock protein HSP90 0.0078 0.083 1
Schistosoma mansoni hypothetical protein 0.0043 0.0404 0.0404
Echinococcus granulosus sex peptide receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0063 0.0635 1
Echinococcus multilocularis musashi 0.0033 0.0272 0.0272
Entamoeba histolytica hypothetical protein 0.0043 0.0404 0.4867
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0016 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Trichomonas vaginalis rotamase, putative 0.0039 0.0354 0.1055
Echinococcus multilocularis caspase 2 0.0064 0.0655 0.0655
Trypanosoma cruzi DNA polymerase eta, putative 0.0054 0.0533 0.6422
Echinococcus granulosus dnaJ subfamily B 0.0494 0.5877 0.5877
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0088 0.0089
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0655 0.1949
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Trichomonas vaginalis heat shock protein, putative 0.0032 0.0267 0.0794
Echinococcus multilocularis thyroid hormone receptor alpha 0.0012 0.0024 0.0024
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0019 0.0108 0.0108
Echinococcus granulosus g protein coupled receptor 0.0828 0.9935 0.9935
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Trypanosoma cruzi heat shock protein 85, putative 0.0078 0.083 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0037 0.0323 0.0323
Giardia lamblia Grp94/Hsp90 0.0063 0.0635 0.7659
Treponema pallidum heat shock protein 90 0.0063 0.0635 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Echinococcus granulosus tm gpcr rhodopsin 0.0828 0.9935 0.9935
Trypanosoma brucei heat shock protein 90, putative 0.0078 0.083 1
Loa Loa (eye worm) intermediate filament protein 0.0033 0.0272 0.0273
Schistosoma mansoni myosin xvIII 0.0828 0.9935 0.9935
Onchocerca volvulus Neuropeptide F receptor homolog 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus granulosus neuropeptides capa receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0019 0.0108 0.1696
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0012 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0016 0.007 0.007
Giardia lamblia Heat shock protein HSP 90-alpha 0.0063 0.0635 0.7659
Schistosoma mansoni biogenic amine receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) neuropeptide F receptor 0.0828 0.9935 1
Echinococcus multilocularis neuropeptide Y receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0252 0.2939 0.2958
Loa Loa (eye worm) hypothetical protein 0.0033 0.0275 0.0277
Mycobacterium ulcerans putative regultory protein 0.0016 0.007 0.1105
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0012 0.0024 0.0024
Trypanosoma cruzi DNA topoisomerase II, putative 0.0016 0.007 0.0846
Onchocerca volvulus 0.0828 0.9935 1
Echinococcus multilocularis expressed protein 0.004 0.0366 0.0366
Loa Loa (eye worm) hypothetical protein 0.0286 0.3345 0.3367
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0016 0.007 0.1105
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Trypanosoma brucei metacaspase 0.0064 0.0655 0.7892
Mycobacterium ulcerans DNA gyrase subunit B 0.0016 0.007 0.1105
Echinococcus multilocularis rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Onchocerca volvulus 0.0012 0.0024 0.0024
Echinococcus multilocularis tumor protein p63 0.0408 0.4833 0.4833
Trypanosoma cruzi heat shock protein 85, putative 0.0063 0.0635 0.7659
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0037 0.0323 0.0323
Schistosoma mansoni pyruvate dehydrogenase 0.0016 0.007 0.007
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0023 0.0159 0.0159
Echinococcus granulosus neuropeptide Y receptor 0.0828 0.9935 0.9935
Trypanosoma brucei heat shock protein, putative 0.0078 0.083 1
Brugia malayi hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0323 0.0323
Echinococcus multilocularis dro:myosuppressin receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis sex peptide receptor 0.0828 0.9935 0.9935
Trichomonas vaginalis set domain proteins, putative 0.0287 0.336 1
Brugia malayi hypothetical protein 0.0828 0.9935 1
Leishmania major DNA polymerase eta, putative 0.0038 0.0338 0.4069
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0108 0.0108
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0039 0.0354 0.4273
Echinococcus granulosus hypothetical protein 0.0828 0.9935 0.9935
Brugia malayi Pre-SET motif family protein 0.0252 0.2939 0.2958
Echinococcus granulosus biogenic amine 5HT receptor 0.0828 0.9935 0.9935
Echinococcus granulosus ecdysone induced protein 78C 0.0012 0.0024 0.0024
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0012 0.0024 0.0024
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0828 0.9935 0.9935
Echinococcus multilocularis g-protein coupled receptor 0.0828 0.9935 0.9935
Brugia malayi hypothetical protein 0.0033 0.0275 0.0277
Echinococcus granulosus neuropeptides capa receptor 0.0828 0.9935 0.9935
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0012 0.0024 0.0024
Trypanosoma cruzi DNA topoisomerase II, putative 0.0016 0.007 0.0846
Schistosoma mansoni biogenic amine receptor 0.0828 0.9935 0.9935
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0655 0.1949
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus granulosus heat shock protein 90 0.0078 0.083 0.083
Entamoeba histolytica deoxycytidyl transferase, putative 0.0023 0.0159 0.1918
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0016 0.007 0.1105
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0012 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0064 0.0655 0.0659
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Onchocerca volvulus 0.0828 0.9935 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Echinococcus multilocularis ecdysone induced protein 78C 0.0012 0.0024 0.0024
Trypanosoma cruzi metacaspase 5, putative 0.0064 0.0655 0.7892
Brugia malayi Endoplasmin precursor 0.0078 0.083 0.0835
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0016 0.007 0.1105
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0016 0.007 0.1105
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni opsin-like receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0108 0.0108
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0023 0.0159 0.0159
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0016 0.007 0.1105
Echinococcus multilocularis neuropeptide receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis g protein coupled receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0037 0.0323 0.0325
Brugia malayi kinase, mitochondrial precursor 0.0016 0.007 0.0071
Echinococcus granulosus rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0016 0.007 0.0071
Brugia malayi hypothetical protein 0.0828 0.9935 1
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0338 0.4069
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0012 0.0024 0.0024
Trypanosoma brucei developmentally regulated phosphoprotein 0.0016 0.007 0.0846
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.024 0.2789 0.2789
Echinococcus granulosus neuropeptide FF receptor 2 0.0828 0.9935 0.9935
Toxoplasma gondii isocitrate dehydrogenase 0.0019 0.0108 0.1299
Trypanosoma brucei heat shock protein, putative 0.0078 0.083 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis caspase 8 0.0064 0.0655 0.0655
Loa Loa (eye worm) steroid hormone receptor 0.0012 0.0024 0.0024
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0016 0.007 0.0846
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0043 0.0404 0.0404
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0032 0.0267 0.0267
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0063 0.0635 0.0635
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0655 0.1949
Echinococcus multilocularis rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Brugia malayi neuropeptide F receptor 0.0828 0.9935 1
Chlamydia trachomatis DNA gyrase subunit B 0.0016 0.007 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0012 0.0024 0.0024
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.004 0.0366 0.0368
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0037 0.0323 0.3895
Plasmodium vivax SET domain protein, putative 0.0037 0.0323 0.3895
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0602 0.0602
Plasmodium vivax heat shock protein 86, putative 0.0078 0.083 1
Onchocerca volvulus 0.0037 0.0323 0.0325
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0012 0.0024 0.0024
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0828 0.9935 0.9935
Echinococcus multilocularis G-protein coupled receptor, putative 0.0828 0.9935 0.9935
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0064 0.0655 0.7892
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0037 0.0323 0.0323
Plasmodium falciparum endoplasmin, putative 0.0048 0.0461 0.5556
Entamoeba histolytica heat shock protein 90, putative 0.0078 0.083 1
Brugia malayi larval opioid receptor 0.0828 0.9935 1
Brugia malayi hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0024 0.0024
Trypanosoma brucei heat shock protein 84, putative 0.0032 0.0267 0.3215
Mycobacterium tuberculosis Probable two component sensor kinase 0.0016 0.007 0.1105
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0012 0.0024 0.0024
Brugia malayi Intermediate filament tail domain containing protein 0.0033 0.0272 0.0273
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni opsin-like receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0828 0.9935 0.9935
Brugia malayi putative neuropeptide receptor NPR1 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0016 0.007 0.0209
Echinococcus multilocularis caspase 0.024 0.2789 0.2789
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0012 0.0024 0.0024
Loa Loa (eye worm) endoplasmin 0.0078 0.083 0.0835
Brugia malayi hypothetical protein 0.0828 0.9935 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0828 0.9935 0.9935
Echinococcus multilocularis caspase 3 0.0176 0.201 0.201
Echinococcus multilocularis serotonin receptor 0.0828 0.9935 0.9935
Brugia malayi hypothetical protein 0.0286 0.3345 0.3367
Schistosoma mansoni hypothetical protein 0.0828 0.9935 0.9935
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0016 0.007 0.0071
Trichomonas vaginalis heat shock protein, putative 0.0063 0.0635 0.1891
Trypanosoma brucei heat shock protein, putative 0.0078 0.083 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0828 0.9935 1
Trypanosoma cruzi metacaspase, putative 0.0064 0.0655 0.7892
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0019 0.0108 0.0108
Onchocerca volvulus 0.0033 0.0272 0.0273
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0023 0.0159 0.0474
Plasmodium vivax heat shock protein 90, putative 0.0032 0.0267 0.3215
Schistosoma mansoni cpg binding protein 0.0037 0.0321 0.0321
Brugia malayi ImpB/MucB/SamB family protein 0.0023 0.0159 0.016
Entamoeba histolytica hypothetical protein 0.0043 0.0404 0.4867
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.006
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0088 0.0089
Loa Loa (eye worm) hypothetical protein 0.0015 0.006 0.006
Echinococcus granulosus lamin dm0 0.0033 0.0272 0.0272
Echinococcus multilocularis g protein coupled receptor 0.0828 0.9935 0.9935
Schistosoma mansoni thyroid hormone receptor 0.0012 0.0024 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Entamoeba histolytica hypothetical protein 0.0043 0.0404 0.4867
Schistosoma mansoni nuclear hormone receptor 0.0012 0.0024 0.0024
Echinococcus granulosus allatostatin A receptor 0.0828 0.9935 0.9935
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0012 0.0022 0.0022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Echinococcus multilocularis neuropeptide receptor A26 0.0828 0.9935 0.9935
Trypanosoma brucei DNA topoisomerase ii 0.0016 0.007 0.0846
Trypanosoma cruzi heat shock protein 85, putative 0.0078 0.083 1
Schistosoma mansoni hypothetical protein 0.0033 0.0275 0.0275
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0012 0.0024 0.0024
Echinococcus multilocularis neuropeptide receptor 0.0828 0.9935 0.9935
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0828 0.9935 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0828 0.9935 1
Plasmodium falciparum metacaspase 1 0.0064 0.0655 0.7892
Trichomonas vaginalis DNA topoisomerase II, putative 0.0016 0.007 0.0209
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0025 0.0301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0828 0.9935 0.9935
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0016 0.007 0.0071
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0016 0.007 0.0071
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0012 0.0024 0.0024
Onchocerca volvulus 0.0828 0.9935 1
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Echinococcus multilocularis dna polymerase kappa 0.0023 0.0159 0.0159
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0058 0.0584 0.0587
Echinococcus multilocularis neuropeptides capa receptor 0.0828 0.9935 0.9935
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0023 0.0159 0.016
Leishmania major DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Trichomonas vaginalis DNA polymerase eta, putative 0.0023 0.0159 0.0474
Plasmodium falciparum heat shock protein 90 0.0078 0.083 1
Trypanosoma cruzi metacaspase, putative 0.0064 0.0655 0.7892
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0016 0.007 0.1105
Schistosoma mansoni adenoreceptor 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0071
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0012 0.0024 0.0024
Plasmodium falciparum DNA gyrase subunit B 0.0016 0.007 0.0846
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0828 0.9935 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0828 0.9935 0.9935
Toxoplasma gondii heat shock protein 75, putative 0.0032 0.0267 0.3215
Brugia malayi heat shock protein 90 0.0078 0.083 0.0835
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0064 0.0655 0.7892
Echinococcus granulosus cpg binding protein 0.0037 0.0321 0.0321
Echinococcus multilocularis rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0032 0.0267 0.0267
Onchocerca volvulus 0.0058 0.0584 0.0587
Onchocerca volvulus 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Schistosoma mansoni endoplasmin 0.0078 0.083 0.083
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0016 0.0067 0.0067
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0016 0.007 0.0846
Trypanosoma cruzi metacaspase, putative 0.0064 0.0655 0.7892
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0012 0.0024 0.0024
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0016 0.007 0.1105
Trichomonas vaginalis heat shock protein, putative 0.0063 0.0635 0.1891
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0159 0.2504
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Toxoplasma gondii peptidylprolyl isomerase 0.0039 0.0354 0.4273
Brugia malayi Hsp90 protein 0.0032 0.0267 0.0269
Echinococcus granulosus 7tm_1 domain containing protein 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0016 0.0067 0.0067
Leishmania major peptidyl-prolyl cis-trans isomerase, putative 0.0012 0.0025 0.0301
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus granulosus serotonin receptor 0.0828 0.9935 0.9935
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0016 0.007 0.1105
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0016 0.007 0.1105
Toxoplasma gondii heat shock protein 90, putative 0.0078 0.083 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0828 0.9935 0.9935
Echinococcus granulosus neuropeptide receptor 0.0828 0.9935 0.9935
Echinococcus granulosus G protein coupled receptor 139 0.0828 0.9935 0.9935
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.004 0.0366 0.0368
Schistosoma mansoni cpg binding protein 0.0035 0.0297 0.0297
Onchocerca volvulus 0.0828 0.9935 1
Brugia malayi Melatonin receptor type 1A 0.0828 0.9935 1
Onchocerca volvulus Cell death protein 3 homolog 0.0064 0.0655 0.0659
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0828 0.9935 0.9935
Echinococcus granulosus neuropeptide receptor A26 0.0828 0.9935 0.9935
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0035 0.0298 0.0298
Echinococcus granulosus neuropeptide Y receptor 0.0828 0.9935 0.9935
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0012 0.0024 0.0024
Echinococcus multilocularis cpg binding protein 0.0037 0.0321 0.0321
Brugia malayi Temporarily assigned gene name protein 44 0.0033 0.0275 0.0277
Onchocerca volvulus 0.0033 0.0272 0.0273
Echinococcus multilocularis rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0016 0.007 0.0741
Onchocerca volvulus 0.006 0.0602 0.0605
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0012 0.0024 0.0024
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0012 0.0024 0.0024
Mycobacterium ulcerans DNA polymerase IV 0.0023 0.0159 0.2504
Onchocerca volvulus 0.0828 0.9935 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0023 0.0159 0.0159
Leishmania major heat shock protein 83-1 0.0078 0.083 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0828 0.9935 0.9935
Trypanosoma cruzi heat shock protein, putative 0.0032 0.0267 0.3215
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0023 0.0159 0.1918
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0016 0.007 0.1105
Loa Loa (eye worm) heat shock protein 90 0.0078 0.083 0.0835
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0012 0.0024 0.0024
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Echinococcus granulosus survival motor neuron protein 1 0.0286 0.3345 0.3345
Loa Loa (eye worm) hypothetical protein 0.0016 0.007 0.0071
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0039 0.0354 0.4273
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0016 0.007 0.1105
Trypanosoma brucei heat shock protein, putative 0.0078 0.083 1
Onchocerca volvulus 0.0828 0.9935 1
Trichomonas vaginalis sensor histidine kinase, putative 0.0016 0.007 0.0209
Schistosoma mansoni eyes absent homolog 0.0106 0.1169 0.1169
Schistosoma mansoni hypothetical protein 0.0828 0.9935 0.9935
Toxoplasma gondii Hsp90 domain-containing protein 0.0032 0.0267 0.3215
Leishmania major mitochondrial DNA topoisomerase II 0.0016 0.007 0.0846
Echinococcus granulosus hypothetical protein 0.0033 0.0275 0.0275
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0064 0.0655 0.1949
Echinococcus granulosus tachykinin peptides receptor 99D 0.0828 0.9935 0.9935
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0024 0.0024
Loa Loa (eye worm) TOPoisomerase family member 0.0016 0.007 0.0071
Schistosoma mansoni lamin 0.0033 0.0272 0.0272
Echinococcus multilocularis neuropeptide FF receptor 2 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0016 0.007 0.0741
Brugia malayi ecdysteroid receptor 0.0012 0.0024 0.0024
Schistosoma mansoni hypothetical protein 0.0494 0.5877 0.5877
Schistosoma mansoni hypothetical protein 0.0828 0.9935 0.9935
Loa Loa (eye worm) hypothetical protein 0.0032 0.0264 0.0266
Loa Loa (eye worm) hypothetical protein 0.0828 0.9935 1
Trichomonas vaginalis heat shock protein, putative 0.0063 0.0635 0.1891
Trypanosoma brucei unspecified product 0.0016 0.0071 0.0859
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0012 0.0024 0.0024
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0019 0.0108 0.1299
Trichomonas vaginalis receptor histidine kinase, putative 0.0016 0.007 0.0209
Echinococcus granulosus g-protein coupled receptor 0.0828 0.9935 0.9935
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0016 0.007 0.0071
Brugia malayi ORL1-like opioid receptor 0.0828 0.9935 1
Echinococcus granulosus tm gpcr rhodopsin 0.0828 0.9935 0.9935
Echinococcus multilocularis G protein coupled receptor 139 0.0828 0.9935 0.9935
Trypanosoma cruzi DNA polymerase kappa, putative 0.0023 0.0159 0.1918
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0828 0.9935 0.9935
Schistosoma mansoni neuropeptide receptor 0.0828 0.9935 0.9935
Echinococcus multilocularis endoplasmin 0.0063 0.0635 0.0635
Echinococcus granulosus rhodopsin orphan GPCR 0.0828 0.9935 0.9935

Activities

Activity type Activity value Assay description Source Reference
EC50 (binding) = 7.894 uM PUBCHEM_BIOASSAY: Absorbance-based biochemical high throughput dose response assay for activators of procaspase-3. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463141, AID463197, AID463210, AID488941, AID488954, AID493114, AID493115, AID504328, AID504330] ChEMBL. No reference
EC50 (binding) = 14.802 uM PUBCHEM_BIOASSAY: Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID463141, AID463197, AID463210, AID488941, AID488954, AID493114, AID493115, AID504328, AID504330] ChEMBL. No reference
EC50 (functional) > 99 uM PUBCHEM_BIOASSAY: Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504720, AID504743] ChEMBL. No reference
EC50 (functional) > 99 uM PUBCHEM_BIOASSAY: Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504720, AID504743] ChEMBL. No reference
IC50 (binding) = 7.308 uM PUBCHEM_BIOASSAY: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of GLD-1 protein - TGE RNA interaction. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID2280, AID2290, AID2459] ChEMBL. No reference
IC50 (functional) = 9.234 um PUBCHEM_BIOASSAY: Tumor Hsp90 Inhibitors Dose Response Confirmation. (Class of assay: confirmatory) [Related pubchem assays: 429 (Primary screen preceding this dose response confirmation assay.)] ChEMBL. No reference
IC50 (binding) > 75.411 um PUBCHEM_BIOASSAY: Counterscreen for inhibitors of gld-1: Fluorescence polarization-based biochemical high throughput dose response assay for inhibitors of the HIV Rev protein-RRE RNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2290 (Summary (gld-1 inhibitors)), 2280 (Primary screen (gld-1 inhibitors in singlicate))] ChEMBL. No reference
Inhibition (binding) % Inhibitory activity of the compound against Chymotrypsinogen at 70 microM concentration; NI = no inhibition ChEMBL. 1578486
Inhibition (binding) % Inhibitory activity of the compound against Porcine Pancreatic Elastase (PPE) at 70 microM concentration; NI = no inhibition ChEMBL. 1578486
Inhibition (binding) % Inhibitory activity of the compound against Human Leukocyte Elastase (HLE) at 70 microM concentration; NI = no inhibition ChEMBL. 1578486
Inhibition (binding) 0 % Inhibitory activity of the compound against Porcine Pancreatic Elastase (PPE) at 70 microM concentration; NI = no inhibition ChEMBL. 1578486
Inhibition (binding) 0 % Inhibitory activity of the compound against Human Leukocyte Elastase (HLE) at 70 microM concentration; NI = no inhibition ChEMBL. 1578486
Inhibition (binding) 0 % Inhibitory activity of the compound against Chymotrypsinogen at 70 microM concentration; NI = no inhibition ChEMBL. 1578486
Inhibition (binding) = 5 % Inhibitory activity of the compound against Cathepsin G (CatG) at 70 microM concentration ChEMBL. 1578486
Inhibition (binding) = 5 % Inhibitory activity of the compound against Cathepsin G (CatG) at 70 microM concentration ChEMBL. 1578486
Inhibition (functional) = 29.22 % Antiinflammatory activity in Kunming mouse assessed as inhibition of xylene-induced auricle tumefaction at 0.2 mmol/kg, po qd administered prior to challenge for 5 days measured 30 mins post challenge ChEMBL. 22901311
Inhibition (functional) = 39.1 % Antiinflammatory activity in Kunming mouse assessed as inhibition of croton oil-induced ear swelling at 0.105 mmol/kg, ig administered for 3 days followed by croton oil challenge at 1 hrs post last dose measured after 4 hrs relative to control ChEMBL. 26471089
Inhibition (ADMET) = 72.57906743 % Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM ChEMBL. 23571415
Inhibition (ADMET) = 86.68783924 % Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM ChEMBL. 23571415
Potency (functional) 1.3115 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 1.4125 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 2.8184 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 3.5481 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) 4.4668 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Eta. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588636] ChEMBL. No reference
Potency (functional) 6.3096 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 7.3078 uM PubChem BioAssay. qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 11.2202 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.1254 uM PubChem BioAssay. qHTS Assay to Find Inhibitors of Pin1. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 14.9589 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 15.8489 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) 16.9469 uM PubChem BioAssay. qHTS for Inhibitors of the Phosphatase Activity of Eya2: Confirmatory Assay for Cherry-picked Compounds. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 19.9526 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) 21.1923 uM PubChem BioAssay. qHTS for Inhibitors of PLK1-PDB (polo-like kinase 1 - polo-box domain): Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3342 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Fructose-1,6-bisphosphate Aldolase from Giardia Lamblia. (Class of assay: confirmatory) [Related pubchem assays: 2472, 2464 ] ChEMBL. No reference
Potency (functional) 23.1093 uM PUBCHEM_BIOASSAY: Nrf2 qHTS screen for inhibitors. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493153, AID493163, AID504648] ChEMBL. No reference
Potency (functional) 23.9145 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Ubiquitin-specific Protease USP2a. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Muscle isoform 2 Pyruvate Kinase. (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (binding) 28.1838 uM PubChem BioAssay. qHTS Assay for Inhibitors of MBNL1-poly(CUG) RNA binding. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Fluorescein Labeled MLL-derived Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Leishmania Mexicana Pyruvate Kinase (LmPK). (Class of assay: confirmatory) [Related pubchem assays: 1379 ] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Leishmania Mexicana Pyruvate Kinase (LmPK). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 33.4889 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 35.4813 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of mutant isocitrate dehydrogenase 1 (IDH1): qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS for Inhibitors of WRN Helicase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 56.2341 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of BAZ2B. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504391] ChEMBL. No reference
Potency (functional) 79.4328 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of JMJD2A-Tudor Domain. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504402] ChEMBL. No reference
Potency (functional) 100 uM PUBCHEM_BIOASSAY: qHTS Assay for the Inhibitors of Human Flap endonuclease 1 (FEN1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488813] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

2 literature references were collected for this gene.

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