Detailed information for compound 681162

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 459.539 | Formula: C21H21N3O5S2
  • H donors: 0 H acceptors: 3 LogP: 2.79 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: C#CCn1c(=NC(=O)c2ccc(cc2)S(=O)(=O)N(C)C)sc2c1cc(OC)c(c2)OC
  • InChi: 1S/C21H21N3O5S2/c1-6-11-24-16-12-17(28-4)18(29-5)13-19(16)30-21(24)22-20(25)14-7-9-15(10-8-14)31(26,27)23(2)3/h1,7-10,12-13H,11H2,2-5H3/b22-21-
  • InChiKey: KDPXFSWOYUBVOZ-DQRAZIAOSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0343 0.0953
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0698 0.1978
Onchocerca volvulus 0.0053 0.0562 0.2738
Schistosoma mansoni bromodomain containing protein 0.0063 0.072 0.2959
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.1372 0.5639
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0013 0.0053
Echinococcus granulosus lamin 0.0053 0.0562 0.0557
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.0013 0.0053
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0043 0.0421 1
Mycobacterium leprae conserved hypothetical protein 0.0107 0.1372 0.5
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0026 0.0014
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0017 0.0018 0.0005
Echinococcus granulosus GPCR family 2 0.0078 0.0943 0.0944
Loa Loa (eye worm) hypothetical protein 0.0107 0.1372 0.3922
Brugia malayi MH2 domain containing protein 0.0242 0.3401 0.9779
Echinococcus granulosus fetal alzheimer antigen falz 0.0023 0.0109 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0159 0.1077
Loa Loa (eye worm) hypothetical protein 0.015 0.2019 0.5791
Schistosoma mansoni zinc finger protein 0.002 0.0064 0.0264
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.1372 1
Giardia lamblia PHD finger protein 15 0.003 0.022 0.2047
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0026 0.0014
Loa Loa (eye worm) hypothetical protein 0.0169 0.2304 0.6615
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0043 0.0421 0.307
Entamoeba histolytica kinesin, putative 0.0027 0.0168 0.3799
Loa Loa (eye worm) hypothetical protein 0.0038 0.0346 0.0962
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0043 0.0421 0.307
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0078 0.0943 0.0944
Echinococcus granulosus jumonji domain containing protein 0.0042 0.0396 0.0388
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.022 0.0904
Schistosoma mansoni smad1 5 8 and 0.0017 0.0018 0.0073
Leishmania major cathepsin L-like protease 0.0062 0.0694 0.5059
Leishmania major hypothetical protein, conserved 0.0107 0.1372 1
Brugia malayi Latrophilin receptor protein 2 0.0078 0.0943 0.2686
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0343 0.141
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0025 0.0153 0.0142
Brugia malayi Bromodomain containing protein 0.0038 0.0345 0.0959
Brugia malayi PHD-finger family protein 0.003 0.022 0.0597
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0094
Loa Loa (eye worm) Smad1 0.0017 0.0018 0.0014
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0694 0.5059
Echinococcus granulosus Smad4 0.0017 0.0018 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0122 0.0801
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0421 0.3004
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0026 0.0014
Trypanosoma cruzi cruzipain precursor, putative 0.0062 0.0694 0.5059
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Brugia malayi jmjC domain containing protein 0.0038 0.0343 0.0953
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0036 0.0309 0.0301
Brugia malayi Bromodomain containing protein 0.0075 0.0895 0.2548
Echinococcus granulosus beta LACTamase domain containing family member 0.0107 0.1372 0.1379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0122 0.0801
Mycobacterium ulcerans hypothetical protein 0.0107 0.1372 0.5
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Plasmodium falciparum kinesin-5 0.0027 0.0168 0.7496
Loa Loa (eye worm) hypothetical protein 0.0051 0.0541 0.1524
Echinococcus multilocularis musashi 0.0053 0.0562 0.0557
Plasmodium vivax hypothetical protein, conserved 0.0107 0.1372 1
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0094
Echinococcus granulosus TGF beta signal transducer SmadC 0.0017 0.0018 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0254 0.1777
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0288 0.2024
Loa Loa (eye worm) hypothetical protein 0.0071 0.0831 0.2362
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0094
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0094
Schistosoma mansoni hypothetical protein 0.0021 0.008 0.0329
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0043 0.0421 0.1731
Schistosoma mansoni lamin 0.0053 0.0562 0.2311
Echinococcus multilocularis peregrin 0.0032 0.0255 0.0246
Brugia malayi MH2 domain containing protein 0.0017 0.0018 0.0014
Schistosoma mansoni smad1 5 8 and 0.0017 0.0018 0.0073
Schistosoma mansoni kinesin eg-5 0.0027 0.0168 0.0691
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0155 0.1049
Schistosoma mansoni smad 0.0017 0.0018 0.0073
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0056 0.0614 0.4475
Loa Loa (eye worm) transcription factor SMAD2 0.0242 0.3401 0.9779
Schistosoma mansoni smad1 5 8 and 0.0017 0.0018 0.0073
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0026 0.0108
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0043 0.0421 0.307
Brugia malayi hypothetical protein 0.015 0.2019 0.5791
Brugia malayi Bromodomain containing protein 0.0032 0.0255 0.07
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0247 0.3477 1
Brugia malayi jmjC domain containing protein 0.0098 0.1242 0.3547
Echinococcus multilocularis tumor protein p63 0.0674 0.9867 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0242 0.3401 0.9779
Schistosoma mansoni Smad4 0.0017 0.0018 0.0073
Loa Loa (eye worm) hypothetical protein 0.0025 0.0153 0.0403
Brugia malayi beta-lactamase family protein 0.0107 0.1372 0.3922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0288 0.2024
Trichomonas vaginalis esterase, putative 0.0107 0.1372 1
Echinococcus multilocularis beta LACTamase domain containing family member 0.0107 0.1372 0.1379
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.1372 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0247 0.3477 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0107 0.1372 0.3922
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0247 0.3477 1
Onchocerca volvulus 0.0107 0.1372 0.6773
Echinococcus multilocularis mothers against decapentaplegic 5 0.0017 0.0018 0.0005
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0207 0.1428
Leishmania major cathepsin L-like protease 0.0062 0.0694 0.5059
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.0041 0.0297
Loa Loa (eye worm) hypothetical protein 0.003 0.022 0.0597
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0107 0.1372 0.3922
Echinococcus multilocularis lamin dm0 0.0053 0.0562 0.0557
Leishmania major cysteine peptidase A (CPA) 0.0016 0.0013 0.0094
Mycobacterium leprae Probable lipase LipE 0.0107 0.1372 0.5
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0036 0.0065
Echinococcus granulosus mothers against decapentaplegic 5 0.0017 0.0018 0.0005
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0043 0.0421 0.0414
Schistosoma mansoni cellular tumor antigen P53 0.0099 0.1248 0.5132
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.1242 0.1247
Loa Loa (eye worm) hypothetical protein 0.0078 0.0943 0.2686
Loa Loa (eye worm) hypothetical protein 0.0247 0.3477 1
Brugia malayi MH1 domain containing protein 0.0017 0.0018 0.0014
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0043 0.0421 0.307
Loa Loa (eye worm) hypothetical protein 0.0017 0.0026 0.0039
Loa Loa (eye worm) hypothetical protein 0.0099 0.1248 0.3566
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0121 0.0797
Mycobacterium ulcerans lipase LipD 0.0107 0.1372 0.5
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.1372 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0382 0.1064
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0078 0.0943 0.0944
Onchocerca volvulus 0.0107 0.1372 0.6773
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0078 0.0943 0.2686
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.008 0.0194
Onchocerca volvulus 0.0107 0.1372 0.6773
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0036 0.0309 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0254 0.1777
Trypanosoma brucei hypothetical protein, conserved 0.0107 0.1372 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0254 0.1777
Plasmodium vivax kinesin-5 0.0027 0.0168 0.1141
Schistosoma mansoni hypothetical protein 0.0078 0.0943 0.3878
Echinococcus multilocularis jumonji domain containing protein 0.0042 0.0396 0.0388
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0121 0.0797
Echinococcus multilocularis zinc finger protein 0.002 0.0064 0.0052
Trichomonas vaginalis PIKK family atypical protein kinase 0.0037 0.0326 0.2304
Brugia malayi PHD-finger family protein 0.0025 0.0144 0.0379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0155 0.1049
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0107 0.1372 0.5
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.0666 0.0663
Echinococcus multilocularis smad 0.0017 0.0018 0.0005
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0343 0.141
Onchocerca volvulus 0.0053 0.0562 0.2738
Trichomonas vaginalis penicillin-binding protein, putative 0.0107 0.1372 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0138 0.0361
Mycobacterium ulcerans beta-lactamase 0.0107 0.1372 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0254 0.1777
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0053 0.0562 0.1585
Loa Loa (eye worm) beta-lactamase 0.0107 0.1372 0.3922
Schistosoma mansoni hypothetical protein 0.0078 0.0943 0.3878
Loa Loa (eye worm) MH2 domain-containing protein 0.0017 0.0018 0.0014
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.022 0.021
Giardia lamblia GTOR 0.0043 0.0421 1
Brugia malayi Intermediate filament tail domain containing protein 0.0053 0.0562 0.1585
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0078 0.0943 0.0944
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0026 0.0014
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0121 0.0797
Loa Loa (eye worm) PHD-finger family protein 0.003 0.022 0.0597
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0288 0.2024
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0026 0.0108
Loa Loa (eye worm) hypothetical protein 0.0107 0.1372 0.3922
Loa Loa (eye worm) hypothetical protein 0.0025 0.0138 0.0361
Plasmodium vivax hypothetical protein, conserved 0.003 0.022 0.1522
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.022 0.1522
Trichomonas vaginalis PIKK family atypical protein kinase 0.0028 0.0193 0.1324
Echinococcus granulosus lamin dm0 0.0053 0.0562 0.0557
Schistosoma mansoni hypothetical protein 0.0178 0.2432 1
Brugia malayi Kinesin motor domain containing protein 0.0027 0.0168 0.0448
Plasmodium falciparum phd finger protein, putative 0.003 0.022 1
Leishmania major cathepsin L-like protease 0.0016 0.0013 0.0094
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.1242 0.1247
Echinococcus granulosus intermediate filament protein 0.0053 0.0562 0.0557
Loa Loa (eye worm) hypothetical protein 0.0107 0.1372 0.3922
Leishmania major cathepsin L-like protease 0.0062 0.0694 0.5059
Brugia malayi beta-lactamase family protein 0.0107 0.1372 0.3922
Brugia malayi latrophilin 2 splice variant baaae 0.0169 0.2304 0.6615
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0694 0.5059
Onchocerca volvulus Alhambra homolog 0.003 0.022 0.1031
Schistosoma mansoni hypothetical protein 0.0169 0.2304 0.9474
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0043 0.0421 0.0414
Brugia malayi cytoplasmic intermediate filament protein 0.0028 0.0195 0.0525
Toxoplasma gondii ABC1 family protein 0.0107 0.1372 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0254 0.1777
Echinococcus multilocularis lamin 0.0053 0.0562 0.0557
Brugia malayi intermediate filament protein 0.0053 0.0562 0.1585
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0107 0.1372 0.5639
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0043 0.0421 0.1178
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0254 0.1777
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0343 0.0335
Schistosoma mansoni hypothetical protein 0.003 0.022 0.0904
Schistosoma mansoni intermediate filament proteins 0.0053 0.0562 0.2311
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0288 0.2103
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0017 0.0018 0.0073
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.0013 0.0094
Echinococcus multilocularis kinesin family 1 0.0204 0.283 0.2859
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0043 0.0421 0.307
Brugia malayi MH2 domain containing protein 0.0017 0.0018 0.0014
Echinococcus granulosus kinesin family 1 0.0204 0.283 0.2859
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0025 0.0153 0.0142
Loa Loa (eye worm) hypothetical protein 0.0043 0.041 0.1147
Onchocerca volvulus 0.015 0.2019 1
Loa Loa (eye worm) hypothetical protein 0.0107 0.1372 0.3922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0421 0.3004
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.1372 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0159 0.1077
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0122 0.0801
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.022 0.021
Brugia malayi beta-lactamase 0.0107 0.1372 0.3922
Loa Loa (eye worm) kinesin-like protein KLP2 0.0027 0.0168 0.0448
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0288 0.2024
Trichomonas vaginalis PIKK family atypical protein kinase 0.0032 0.0254 0.1777
Loa Loa (eye worm) hypothetical protein 0.0107 0.1372 0.3922
Trichomonas vaginalis PIKK family atypical protein kinase 0.0023 0.0122 0.0801
Trypanosoma cruzi cysteine peptidase, putative 0.0062 0.0694 0.5059
Loa Loa (eye worm) hypothetical protein 0.0052 0.0548 0.1544
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0078 0.057
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0023 0.0109 0.0447
Echinococcus granulosus peregrin 0.0032 0.0255 0.0246
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0314 0.0306
Loa Loa (eye worm) intermediate filament protein 0.0053 0.0562 0.1585
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Toxoplasma gondii target of rapamycin (TOR), putative 0.0032 0.0254 0.1777
Onchocerca volvulus 0.0099 0.1248 0.6158
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0026 0.0108
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Schistosoma mansoni hypothetical protein 0.0078 0.0943 0.3878
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.0666 0.0663
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0028 0.0195 0.0525
Trichomonas vaginalis D-aminoacylase, putative 0.0107 0.1372 1
Toxoplasma gondii kinesin motor domain-containing protein 0.0027 0.0168 0.1141
Loa Loa (eye worm) latrophilin receptor protein 2 0.0078 0.0943 0.2686
Loa Loa (eye worm) MH1 domain-containing protein 0.0017 0.0018 0.0014
Schistosoma mansoni lamin 0.0053 0.0562 0.2311
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0062 0.0694 0.5059
Loa Loa (eye worm) hypothetical protein 0.0053 0.0562 0.1585
Trypanosoma cruzi major cysteine proteinase, putative 0.0048 0.0496 0.3618
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0288 0.2103
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0043 0.0421 1
Brugia malayi Smad1 0.0017 0.0018 0.0014
Echinococcus multilocularis GPCR, family 2 0.0078 0.0943 0.0944
Brugia malayi MH1 domain containing protein 0.0017 0.0018 0.0014
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0939 0.3862
Trichomonas vaginalis PIKK family atypical protein kinase 0.0043 0.0421 0.3004
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0159 0.1077
Echinococcus multilocularis Smad4 0.0017 0.0018 0.0005
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0078 0.0943 0.0944
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0023 0.0109 0.0097
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0043 0.0421 0.307
Loa Loa (eye worm) phosphatidylinositol 3 0.0043 0.0421 0.1178
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.022 0.1522
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0288 0.2103
Echinococcus granulosus tumor protein p63 0.0674 0.9867 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0288 0.2024
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0026 0.0108
Loa Loa (eye worm) hypothetical protein 0.0107 0.1372 0.3922
Echinococcus granulosus zinc finger protein 0.002 0.0064 0.0052
Echinococcus granulosus smad 0.0017 0.0018 0.0005
Schistosoma mansoni hypothetical protein 0.0078 0.0943 0.3878
Trypanosoma cruzi hypothetical protein, conserved 0.0107 0.1372 1
Mycobacterium ulcerans esterase/lipase LipP 0.0107 0.1372 0.5

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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