Detailed information for compound 705591

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 385.404 | Formula: C17H18F3N3O2S
  • H donors: 1 H acceptors: 2 LogP: 4.11 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)OC(F)(F)F)CSc1nccn1C1CCCC1
  • InChi: 1S/C17H18F3N3O2S/c18-17(19,20)25-14-7-5-12(6-8-14)22-15(24)11-26-16-21-9-10-23(16)13-3-1-2-4-13/h5-10,13H,1-4,11H2,(H,22,24)
  • InChiKey: UUQVPCSOWSBUOF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0014 0.0061
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0258 0.1107
Leishmania major protein kinase, putative 0.0068 0.0656 0.5482
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0068 0.0657 0.0984
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0014 0.0061
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0004 0.0019
Echinococcus multilocularis caspase 0.0019 0.0125 0.0545
Brugia malayi MH2 domain containing protein 0.0122 0.1238 0.5382
Echinococcus multilocularis calcium dependent protein kinase 0.0063 0.0606 0.2639
Echinococcus granulosus Smad4 0.0008 0.0014 0.0061
Echinococcus granulosus General substrate transporter 0.0189 0.1964 0.8548
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0267 0.0263
Echinococcus multilocularis lysyl tRNA synthetase 0.0049 0.0454 0.1977
Schistosoma mansoni protein kinase 0.0068 0.0656 0.2857
Echinococcus granulosus intermediate filament protein 0.0026 0.021 0.0912
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0656 0.2857
Loa Loa (eye worm) hypothetical protein 0.0037 0.0321 0.138
Chlamydia trachomatis histidine--tRNA ligase 0.0007 0.0005 0.0008
Schistosoma mansoni caspase-7 (C14 family) 0.0019 0.0125 0.0545
Echinococcus multilocularis solute carrier family 22 0.0031 0.0258 0.1124
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trypanosoma cruzi hexose transporter 0.0068 0.066 0.5516
Plasmodium falciparum lysine--tRNA ligase 0.0049 0.0454 0.045
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Plasmodium falciparum proline--tRNA ligase 0.0077 0.0754 0.075
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0267 0.0263
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0058 0.0253
Onchocerca volvulus 0.0031 0.0258 0.1269
Loa Loa (eye worm) phosphofructokinase 0.0118 0.1194 0.5187
Toxoplasma gondii sugar transporter ST2 0.0031 0.0258 0.0383
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0058 0.0451
Brugia malayi lysyl-tRNA synthetase 0.0049 0.0454 0.1962
Schistosoma mansoni cpg binding protein 0.003 0.0245 0.1068
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0066 0.0636 0.277
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.021 0.0895
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0077 0.0318
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0068 0.0657 0.0653
Leishmania major glucose transporter, lmgt3 0.0068 0.066 0.5516
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0258 0.2134
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Brugia malayi major facilitator superfamily protein 0.0031 0.0258 0.1107
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.0754 0.6306
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0125 0.0527
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.1238 0.5382
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0043 0.0389 0.1677
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0345 0.15
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0125 0.0527
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0321 0.1153
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.066 0.2861
Trypanosoma cruzi metacaspase, putative 0.0019 0.0125 0.1016
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0058 0.0081
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0011 0.0043 0.0058
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0125 0.0182
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0258 0.1107
Loa Loa (eye worm) hypothetical protein 0.0037 0.0321 0.138
Brugia malayi hypothetical protein 0.0043 0.0392 0.169
Mycobacterium ulcerans sugar transporter 0.0031 0.0258 0.2134
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2297 1
Echinococcus multilocularis caspase 3, apoptosis cysteine peptidase 0.0019 0.0125 0.0545
Echinococcus multilocularis solute carrier family 22 0.0031 0.0258 0.1124
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0252
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0356 0.3764 0.3761
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0321 0.138
Echinococcus multilocularis aspartyl tRNA synthetase, cytoplasmic 0.0007 0.0004 0.0019
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0548 0.237
Toxoplasma gondii lysine-tRNA ligase 0.0049 0.0454 0.0678
Schistosoma mansoni sugar transporter 0.0031 0.0258 0.1124
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0058 0.0253
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0068 0.0656 0.2843
Trichomonas vaginalis glycyl-tRNA synthetase, putative 0.0007 0.0005 0.0002
Trypanosoma brucei glucose transporter 2A 0.0068 0.066 0.5516
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.0754 0.6306
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0043 0.0321
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0258 0.1124
Leishmania major hypothetical protein, conserved 0.0031 0.0258 0.2134
Loa Loa (eye worm) hypothetical protein 0.0037 0.0321 0.138
Brugia malayi MAP kinase sur-1 0.0058 0.0548 0.237
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Onchocerca volvulus 0.0031 0.0258 0.1269
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0068 0.0656 0.2843
Brugia malayi 6-phosphofructokinase 0.0118 0.1194 0.5187
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0007 0.0005 0.0003
Leishmania major hypothetical protein, conserved 0.0011 0.0043 0.0321
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0004 0.0019
Wolbachia endosymbiont of Brugia malayi histidyl-tRNA synthetase 0.0007 0.0005 0.0014
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0345 0.15
Trypanosoma cruzi metacaspase, putative 0.0019 0.0125 0.1016
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0004 0.0019
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0032 0.0267 0.2212
Schistosoma mansoni glucose transport protein 0.022 0.2297 1
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0566 0.2465
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Mycobacterium ulcerans 6-phosphofructokinase 0.0118 0.1194 1
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0267 0.0397
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0018 0.0123 0.0537
Loa Loa (eye worm) hypothetical protein 0.0066 0.0636 0.2756
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0258 0.2134
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0066 0.0636 0.5314
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0068 0.0657 0.0653
Mycobacterium ulcerans histidyl-tRNA synthetase 0.0007 0.0005 0.0003
Brugia malayi major facilitator superfamily protein 0.0031 0.0258 0.1107
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0058 0.2114
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0267 0.1147
Onchocerca volvulus 0.0043 0.0392 0.4759
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0062 0.0271
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0568 0.2474
Plasmodium falciparum hexose transporter 0.022 0.2297 0.2294
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Entamoeba histolytica hypothetical protein 0.0039 0.0345 0.2861
Plasmodium falciparum metacaspase 1 0.0019 0.0125 0.0121
Echinococcus granulosus histidyl tRNA synthetase 0.0007 0.0005 0.0021
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0566 0.4725
Schistosoma mansoni threonyl-tRNA synthetase 0.0007 0.0005 0.0021
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0017 0.0056
Plasmodium falciparum calcium-dependent protein kinase 4 0.0068 0.0657 0.0653
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0031 0.0258 0.0894
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.006 0.0566 0.217
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0018 0.0123 0.0519
Onchocerca volvulus 0.0031 0.0258 0.1269
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0019 0.0061
Echinococcus multilocularis General substrate transporter 0.0189 0.1964 0.8548
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0465 0.2023
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0058 0.0081
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0656 0.2857
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.1238 0.5382
Loa Loa (eye worm) hypothetical protein 0.0037 0.0321 0.138
Toxoplasma gondii protein kinase, putative 0.0622 0.6633 1
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0176 0.1443
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0062 0.0271
Leishmania major hypothetical protein, conserved 0.0011 0.0043 0.0321
Echinococcus multilocularis 6 phosphofructokinase 0.0118 0.1194 0.5196
Loa Loa (eye worm) hypothetical protein 0.0026 0.021 0.0895
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0321 0.266
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0049 0.0454 0.1962
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0548 0.457
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0321 0.0317
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0007 0.0004 0.0019
Giardia lamblia Glycyl-tRNA synthetase 0.0012 0.0058 0.0849
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Onchocerca volvulus 0.0031 0.0258 0.1269
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0058 0.2114
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0018 0.0123 0.1
Schistosoma mansoni histidyl-tRNA synthetase 0.0007 0.0005 0.0021
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Echinococcus granulosus asparaginyl tRNA synthetase, cytoplasmic 0.0007 0.0004 0.0019
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0258 0.0383
Trypanosoma cruzi metacaspase, putative 0.0019 0.0125 0.1016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0465 0.2023
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0018 0.0123 0.1
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0267 0.1147
Echinococcus granulosus lamin 0.0026 0.021 0.0912
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.066 0.5516
Schistosoma mansoni smad 0.0008 0.0014 0.0061
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0058 0.0234
Trichomonas vaginalis sugar transport protein, putative 0.0031 0.0258 0.1107
Onchocerca volvulus 0.0031 0.0258 0.1269
Trypanosoma brucei histidyl-tRNA synthetase 0.0007 0.0005 0.0003
Trypanosoma cruzi glycyl-tRNA synthetase, putative 0.0007 0.0005 0.0003
Echinococcus granulosus cpg binding protein 0.003 0.0245 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0258 0.1107
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0321 0.266
Brugia malayi hypothetical protein 0.0039 0.0345 0.1484
Brugia malayi beta-lactamase 0.0037 0.0321 0.138
Trypanosoma brucei glucose transporter, putative 0.0068 0.066 0.5516
Onchocerca volvulus 0.0031 0.0258 0.1269
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0566 0.4725
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0321 0.266
Echinococcus multilocularis mitogen activated protein kinase 0.0058 0.0548 0.2385
Brugia malayi MH2 domain containing protein 0.0008 0.0014 0.0042
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0018 0.0123 0.1
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0058 0.0253
Entamoeba histolytica hypothetical protein 0.0039 0.0345 0.2861
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0454 0.3782
Trichomonas vaginalis sugar transporter, putative 0.0068 0.066 0.2861
Mycobacterium tuberculosis Conserved protein 0.0037 0.0321 0.1153
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0018 0.0123 0.0335
Echinococcus granulosus caspase 3 apoptosis cysteine peptidase 0.0019 0.0125 0.0545
Echinococcus granulosus lysyl tRNA synthetase 0.0049 0.0454 0.1977
Schistosoma mansoni smad1 5 8 and 0.0008 0.0014 0.0061
Schistosoma mansoni serine/threonine protein kinase 0.0058 0.0548 0.2385
Schistosoma mansoni glucose transport protein 0.022 0.2297 1
Plasmodium vivax calcium-dependent protein kinase, putative 0.0068 0.0657 0.0653
Trypanosoma brucei metacaspase MCA3 0.0019 0.0125 0.1016
Brugia malayi hypothetical protein 0.0031 0.0258 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0321 0.266
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.1194 1
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.0454 0.3782
Mycobacterium tuberculosis Conserved protein 0.0037 0.0321 0.1153
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0656 0.2857
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0068 0.0657 0.0984
Onchocerca volvulus 0.0031 0.0258 0.1269
Trypanosoma brucei metacaspase MCA2 0.0019 0.0125 0.1016
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0123 0.0119
Loa Loa (eye worm) hypothetical protein 0.0066 0.0636 0.2756
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0066 0.0636 0.277
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0014 0.0042
Leishmania major ATP-dependent phosphofructokinase 0.0118 0.1194 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0321 0.138
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0754 0.6306
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0176 0.1443
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0058 0.0548 0.457
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0267 0.5848
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0018 0.0123 0.1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0057 0.0229
Treponema pallidum exodeoxyribonuclease (exoA) 0.0018 0.0123 0.1
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0321 0.1153
Loa Loa (eye worm) hypothetical protein 0.0054 0.0503 0.2174
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.1194 1
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0321 0.1153
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0125 0.0527
Loa Loa (eye worm) sugar transporter 0.0031 0.0258 0.1107
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0058 0.0548 0.457
Trypanosoma brucei protein kinase, putative 0.0058 0.0548 0.457
Mycobacterium ulcerans beta-lactamase 0.0037 0.0321 0.266
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0321 0.138
Trypanosoma brucei glucose transporter, putative 0.0068 0.066 0.5516
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Schistosoma mansoni hypothetical protein 0.022 0.2297 1
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.1194 0.5187
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0019 0.0081
Leishmania major histidyl-tRNA synthetase, putative 0.0007 0.0005 0.0003
Onchocerca volvulus 0.0031 0.0258 0.1269
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.1194 0.5187
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0058 0.0548 0.237
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0656 0.2857
Loa Loa (eye worm) hypothetical protein 0.0037 0.0321 0.138
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.0465 0.2023
Mycobacterium leprae Probable lipase LipE 0.0037 0.0321 0.2417
Giardia lamblia Hexose transporter 0.0031 0.0258 0.4016
Echinococcus multilocularis asparaginyl tRNA synthetase, cytoplasmic 0.0007 0.0004 0.0019
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0321 0.1153
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0235 0.2456 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0118 0.1194 0.477
Echinococcus multilocularis caspase 8 0.0019 0.0125 0.0545
Echinococcus multilocularis solute carrier family 22 0.0031 0.0258 0.1124
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0258 0.1124
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0018 0.0123 0.0119
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0656 0.2843
Brugia malayi Sugar transporter family protein 0.0031 0.0258 0.1107
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0043 0.0321
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0656 0.2857
Trypanosoma brucei Metacaspase-4 0.0019 0.0125 0.1016
Entamoeba histolytica protein kinase, putative 0.0068 0.0656 0.5482
Schistosoma mansoni Smad4 0.0008 0.0014 0.0061
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0068 0.0656 0.5482
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.1194 0.5187
Schistosoma mansoni lamin 0.0026 0.021 0.0912
Onchocerca volvulus 0.0031 0.0258 0.1269
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.1194 0.5196
Brugia malayi intermediate filament protein 0.0026 0.021 0.0895
Trichomonas vaginalis myo-inositol transporter, putative 0.0031 0.0258 0.1107
Schistosoma mansoni caspase-7 (C14 family) 0.0062 0.0593 0.2579
Brugia malayi beta-lactamase family protein 0.0037 0.0321 0.138
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trypanosoma brucei glucose transporter, putative 0.0068 0.066 0.5516
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2297 1
Brugia malayi Smad1 0.0008 0.0014 0.0042
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0068 0.0656 0.2843
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Treponema pallidum glycyl-tRNA synthetase 0.0007 0.0005 0.0003
Trichomonas vaginalis sugar transporter, putative 0.0068 0.066 0.2861
Leishmania major metacaspase, putative 0.0019 0.0125 0.1016
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0656 0.2857
Giardia lamblia Threonyl-tRNA synthetase 0.0012 0.0058 0.0849
Schistosoma mansoni caspase-3 (C14 family) 0.0019 0.0125 0.0545
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0258 0.2134
Echinococcus multilocularis caspase 2 0.0062 0.0593 0.2579
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0321 0.266
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Chlamydia trachomatis lysine--tRNA ligase 0.0049 0.0454 1
Brugia malayi 6-phosphofructokinase 0.0118 0.1194 0.5187
Mycobacterium ulcerans hypothetical protein 0.0037 0.0321 0.266
Entamoeba histolytica hypothetical protein 0.0049 0.0454 0.3782
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0258 0.1107
Plasmodium falciparum protein kinase 7 0.0622 0.6633 0.6632
Plasmodium vivax hexose transporter 0.022 0.2297 0.2294
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.1194 0.5187
Plasmodium vivax proline--tRNA ligase, putative 0.0077 0.0754 0.075
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.1194 1
Trypanosoma brucei metacaspase 5, putative 0.0019 0.0125 0.1016
Trypanosoma brucei glucose transporter 1E 0.0068 0.066 0.5516
Echinococcus multilocularis musashi 0.0026 0.021 0.0912
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0058 0.0451
Toxoplasma gondii sugar transporter ST1 0.0031 0.0258 0.0383
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.066 0.5516
Toxoplasma gondii exonuclease III APE 0.0018 0.0123 0.0179
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.0374 0.1375
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0123 0.0519
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0058 0.0548 0.082
Onchocerca volvulus 0.0037 0.0321 0.2904
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0058 0.0234
Schistosoma mansoni ap endonuclease 0.0018 0.0123 0.0537
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0258 0.0254
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0125 0.0527
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0066 0.0636 0.2756
Echinococcus granulosus caspase 0.0019 0.0125 0.0545
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0049 0.0454 0.3782
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0656 0.2857
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0321 0.1396
Onchocerca volvulus 0.0028 0.0228 0.0483
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0058 0.0548 0.457
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0058 0.0451
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.05 0.0747
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trypanosoma brucei glucose transporter, putative 0.0068 0.066 0.5516
Schistosoma mansoni smad1 5 8 and 0.0008 0.0014 0.0061
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.0374 0.2883
Leishmania major glucose transporter, lmgt2 0.0068 0.066 0.5516
Schistosoma mansoni cpg binding protein 0.003 0.0245 0.1068
Giardia lamblia Sugar-proton symporter 0.0031 0.0258 0.4016
Schistosoma mansoni lamin 0.0026 0.021 0.0912
Brugia malayi MH2 domain containing protein 0.0008 0.0014 0.0042
Schistosoma mansoni hypothetical protein 0.0039 0.0345 0.15
Onchocerca volvulus 0.0031 0.0258 0.1269
Echinococcus granulosus mitogen activated protein kinase 0.0058 0.0548 0.2385
Schistosoma mansoni histidyl-tRNA synthetase 0.0007 0.0005 0.0021
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0465 0.2023
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0321 0.1396
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0258 0.1124
Echinococcus multilocularis lamin 0.0026 0.021 0.0912
Onchocerca volvulus Cell death protein 3 homolog 0.0062 0.0593 1
Onchocerca volvulus 0.0031 0.0258 0.1269
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0321 0.138
Echinococcus multilocularis asparaginyl tRNA synthetase 0.0007 0.0004 0.0019
Trypanosoma cruzi glucose transporter, putative 0.0031 0.0258 0.2134
Giardia lamblia Lysyl-tRNA synthetase 0.0049 0.0454 0.7117
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.006 0.0566 0.4725
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0049 0.0454 0.3782
Loa Loa (eye worm) 6-phosphofructokinase 0.0118 0.1194 0.5187
Leishmania major glycyl tRNA synthetase, putative 0.0007 0.0005 0.0003
Echinococcus granulosus mitogen activated protein kinase 3 0.0058 0.0548 0.2385
Entamoeba histolytica hypothetical protein 0.0039 0.0345 0.2861
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0125 0.0527
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0058 0.0548 0.457
Loa Loa (eye worm) Smad1 0.0008 0.0014 0.0042
Trypanosoma brucei glucose transporter, putative 0.0068 0.066 0.5516
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0049 0.0454 0.3576
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0014 0.0061
Trichomonas vaginalis conserved hypothetical protein 0.022 0.2297 1
Echinococcus granulosus solute carrier family 22 0.0031 0.0258 0.1124
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0058 0.0548 0.457
Plasmodium vivax CDK-related protein kinase 6, putative 0.0935 1 1
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0267 0.0263
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0031 0.0258 0.2134
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0321 0.2417
Toxoplasma gondii facilitative glucose transporter GT1 0.022 0.2297 0.3459
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0636 0.277
Trypanosoma brucei metacaspase 0.0019 0.0125 0.1016
Echinococcus multilocularis Smad4 0.0008 0.0014 0.0061
Mycobacterium tuberculosis Conserved protein 0.0037 0.0321 0.1153
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0004 0.0019
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0321 0.1153
Loa Loa (eye worm) hypothetical protein 0.0019 0.0125 0.0527
Mycobacterium ulcerans lipase LipD 0.0037 0.0321 0.266
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.0019 0.0125 0.0527
Echinococcus granulosus caspase 2 0.0062 0.0593 0.2579
Echinococcus granulosus lamin dm0 0.0026 0.021 0.0912
Onchocerca volvulus 0.0031 0.0258 0.1269
Giardia lamblia Kinase, CMGC MAPK 0.0058 0.0548 0.8599
Echinococcus multilocularis lamin dm0 0.0026 0.021 0.0912
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0321 0.138
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0345 0.15
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0258 0.1107
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0058 0.0234
Onchocerca volvulus 0.0037 0.0321 0.2904
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0018 0.0123 0.1
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.0465 0.2008
Toxoplasma gondii anticodon binding domain-containing protein 0.0007 0.0005 0.0001
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2297 1
Onchocerca volvulus 0.0031 0.0258 0.1269
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0267 0.1147
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0068 0.0657 0.0653
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0356 0.3764 0.5671
Schistosoma mansoni 6-phosphofructokinase 0.0118 0.1194 0.5196
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0058 0.0451
Echinococcus granulosus apoptotic protease activating factor 1 0.0043 0.0392 0.1706
Toxoplasma gondii histidyl-tRNA synthetase (HisRS), putative 0.0007 0.0005 0.0001
Echinococcus granulosus calcium dependent protein kinase 0.0063 0.0606 0.2639
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0327 0.2711
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0058 0.0234
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0656 0.2857
Echinococcus granulosus solute carrier family 22 0.0031 0.0258 0.1124
Echinococcus multilocularis mitogen activated protein kinase 3 0.0058 0.0548 0.2385
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0018 0.0123 0.4686
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0267 0.0263
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.021 0.0895
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0032 0.0267 0.1147
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0068 0.0656 0.2857
Echinococcus multilocularis solute carrier family 22 0.0031 0.0258 0.1124
Plasmodium vivax threonine--tRNA ligase, putative 0.0012 0.0058 0.0054
Entamoeba histolytica histidyl-tRNA synthetase, putative 0.0007 0.0005 0.0003
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0258 0.1107
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0754 0.6306
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0014 0.0061
Echinococcus granulosus 6 phosphofructokinase 0.0118 0.1194 0.5196
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0031 0.0258 0.0894
Trichomonas vaginalis glucose transporter, putative 0.0068 0.066 0.2861
Brugia malayi exodeoxyribonuclease III family protein 0.0018 0.0123 0.0519
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0004 0.0019
Onchocerca volvulus 0.0031 0.0258 0.1269
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0043 0.0321
Loa Loa (eye worm) beta-lactamase 0.0037 0.0321 0.138
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0118 0.1194 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0058 0.0548 0.457
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Schistosoma mansoni cpg binding protein 0.0028 0.0228 0.0993
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0548 0.237
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0077 0.0318
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0019 0.0081
Loa Loa (eye worm) hypothetical protein 0.0049 0.0454 0.1962
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0258 0.2134
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0258 0.1107
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0058 0.0253
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0636 0.277
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Echinococcus multilocularis apoptotic protease activating factor 1 0.0043 0.0392 0.1706
Echinococcus granulosus solute carrier family 22 0.0031 0.0258 0.1124
Brugia malayi MH1 domain containing protein 0.0008 0.0014 0.0042
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0548 0.237
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2297 1
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Plasmodium falciparum mitogen-activated protein kinase 2 0.0356 0.3764 0.3761
Entamoeba histolytica protein kinase, putative 0.0068 0.0656 0.5482
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0465 0.2023
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0068 0.0657 0.0984
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0125 0.0182
Echinococcus granulosus aspartyl tRNA synthetase cytoplasmic 0.0007 0.0004 0.0019
Loa Loa (eye worm) hypothetical protein 0.0026 0.0204 0.0872
Trypanosoma cruzi metacaspase, putative 0.0019 0.0125 0.1016
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.006 0.0566 0.2465
Loa Loa (eye worm) hypothetical protein 0.0012 0.0058 0.0234
Schistosoma mansoni ap endonuclease 0.0018 0.0123 0.0537
Loa Loa (eye worm) histidyl-tRNA synthetase 0.0007 0.0005 0.0002
Echinococcus granulosus solute carrier family 22 0.0031 0.0258 0.1124
Toxoplasma gondii ICE family protease (caspase) p20 domain-containing protein 0.0019 0.0125 0.0182
Loa Loa (eye worm) hypothetical protein 0.0068 0.0656 0.2843
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Brugia malayi MH1 domain containing protein 0.0008 0.0014 0.0042
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0058 0.0234
Leishmania major glucose transporter/membrane transporter D2, putative 0.0068 0.066 0.5516
Loa Loa (eye worm) hypothetical protein 0.0062 0.0593 0.2565
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0018 0.0123 0.1
Trypanosoma cruzi hexose transporter, putative 0.0068 0.066 0.5516
Trichomonas vaginalis interferon-induced, double-stranded RNA-activated protein kinase, putative 0.0007 0.0005 0.0002
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0258 0.1107
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0258 0.1107
Mycobacterium ulcerans hypothetical protein 0.0011 0.0043 0.0321
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0258 0.1124
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.0166
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Brugia malayi CXXC zinc finger family protein 0.0028 0.0228 0.0976
Trichomonas vaginalis sugar transporter, putative 0.0068 0.066 0.2861
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0066 0.0636 0.2756
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0228 0.0976
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0066 0.0636 0.5159
Leishmania major glucose transporter, lmgt1 0.0068 0.066 0.5516
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trichomonas vaginalis phosphofructokinase, putative 0.0118 0.1194 0.5187
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0014 0.0061
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0018 0.0123 0.0537
Echinococcus multilocularis smad 0.0008 0.0014 0.0061
Brugia malayi Sugar transporter family protein 0.0031 0.0258 0.1107
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Plasmodium vivax sugar transporter, putative 0.0031 0.0258 0.0254
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0217 0.0926
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0058 0.0451
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.066 0.5516
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0258 0.1107
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0176 0.3815
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0454 0.1977
Toxoplasma gondii aldehyde dehydrogenase 0.006 0.0566 0.0848
Schistosoma mansoni aldehyde dehydrogenase 0.006 0.0566 0.2465
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0321 0.138
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0321 0.138
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0018 0.0123 0.1882
Brugia malayi Cam kinase protein 1 0.0068 0.0656 0.2843
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0058 0.0064
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0058 0.0253
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0043 0.0321
Plasmodium vivax glycine--tRNA ligase, putative 0.0012 0.0058 0.0054
Plasmodium falciparum calcium-dependent protein kinase 1 0.0068 0.0657 0.0653
Plasmodium vivax lysine--tRNA ligase, putative 0.0049 0.0454 0.045
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0032 0.0267 0.2212
Schistosoma mansoni sugar transporter 0.0031 0.0258 0.1124
Schistosoma mansoni intermediate filament proteins 0.0026 0.021 0.0912
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0014 0.0042
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.0754 0.6306
Leishmania major lysyl-tRNA synthetase, putative 0.0049 0.0454 0.3782
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Brugia malayi beta-lactamase family protein 0.0037 0.0321 0.138
Trypanosoma cruzi histidyl-tRNA synthetase 0.0007 0.0005 0.0003
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0267 0.1147
Schistosoma mansoni subfamily C14A unassigned peptidase (C14 family) 0.0019 0.0125 0.0545
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.0166
Toxoplasma gondii ABC1 family protein 0.0037 0.0321 0.0477
Entamoeba histolytica hypothetical protein 0.0039 0.0345 0.2861
Trichomonas vaginalis ap endonuclease, putative 0.0018 0.0123 0.0519
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0004 0.0019
Echinococcus granulosus smad 0.0008 0.0014 0.0061
Plasmodium vivax metacaspase 1, putative 0.0019 0.0125 0.0121
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Schistosoma mansoni hypothetical protein 0.0043 0.0392 0.1706
Onchocerca volvulus 0.0031 0.0258 0.1269
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0267 0.0397
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0321 0.1396
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0066 0.0636 0.2756
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0125 0.1016
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0321 0.1153
Loa Loa (eye worm) hypothetical protein 0.0043 0.0392 0.169
Plasmodium vivax hypothetical protein, conserved 0.0019 0.0125 0.0121
Mycobacterium ulcerans aldehyde dehydrogenase 0.006 0.0566 0.4725
Giardia lamblia Prolyl-tRNA synthetase 0.0066 0.0636 1
Entamoeba histolytica phosphofructokinase, putative 0.0118 0.1194 1
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0058 0.0054
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.0465 0.2023
Plasmodium falciparum calcium-dependent protein kinase 3 0.0068 0.0657 0.0653
Onchocerca volvulus Putative transporter 0.0031 0.0258 0.1269
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0118 0.1194 1
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2297 1
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0267 0.4162
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2297 1
Trypanosoma brucei glucose transporter, putative 0.0068 0.066 0.5516
Loa Loa (eye worm) hypothetical protein 0.0012 0.0057 0.0229
Trypanosoma cruzi hexose transporter, putative 0.0068 0.066 0.5516
Echinococcus granulosus asparaginyl tRNA synthetase cytoplasmic 0.0007 0.0004 0.0019
Brugia malayi hypothetical protein 0.0031 0.0258 0.1107
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Trichomonas vaginalis CMGC family protein kinase 0.0058 0.0548 0.237
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0267 0.5848
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0004 0.0019
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0058 0.0451
Trichomonas vaginalis glucose transporter, putative 0.0068 0.066 0.2861
Leishmania major hypothetical protein, conserved 0.0037 0.0321 0.266
Trypanosoma brucei glucose transporter, putative 0.0068 0.066 0.5516
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0058 0.0451
Schistosoma mansoni aspartyl-tRNA synthetase 0.0007 0.0004 0.0019
Plasmodium falciparum calcium-dependent protein kinase 2 0.0068 0.0657 0.0653
Schistosoma mansoni protein kinase 0.0068 0.0656 0.2857
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0058 0.0234
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0267 0.1147
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0042 0.0374 0.1375
Trypanosoma brucei sugar transporter, putative 0.0031 0.0258 0.2134
Echinococcus granulosus caspase 8 0.0019 0.0125 0.0545
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.0465 0.2023
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Schistosoma mansoni sugar transporter 0.0031 0.0258 0.1124
Echinococcus multilocularis histidyl tRNA synthetase 0.0007 0.0005 0.0021
Chlamydia trachomatis threonine--tRNA ligase 0.0012 0.0058 0.1193
Leishmania major myo-inositol/proton symporter (MIT) 0.0031 0.0258 0.2134
Schistosoma mansoni protein kinase 0.0068 0.0656 0.2857
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Schistosoma mansoni glucose transporter 0.0031 0.0258 0.1124
Onchocerca volvulus 0.0037 0.0321 0.2904
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0258 0.1124
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0058 0.0451
Brugia malayi Sugar transporter family protein 0.022 0.2297 1
Trypanosoma cruzi metacaspase 5, putative 0.0019 0.0125 0.1016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0321 0.138
Loa Loa (eye worm) intermediate filament protein 0.0026 0.021 0.0895
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.0465 0.2008
Trichomonas vaginalis Clan CD, family C14, metacaspase-like cysteine peptidase 0.0019 0.0125 0.0527
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0043 0.0321
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0118 0.1194 1
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0321 0.1396
Trichomonas vaginalis phosphofructokinase, putative 0.0032 0.0267 0.1147
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0258 0.1107
Trypanosoma brucei glucose transporter, putative 0.0068 0.066 0.5516
Brugia malayi phosphofructokinase 0.0118 0.1194 0.5187
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.022 0.2297 1
Loa Loa (eye worm) sugar transporter 0.022 0.2297 1
Plasmodium falciparum metacaspase-like protein 0.0019 0.0125 0.0121
Onchocerca volvulus 0.0031 0.0258 0.1269
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.0454 0.1977
Brugia malayi mucosa associated lymphoid tissue lymphoma translocation protein 1 0.0019 0.0125 0.0527
Echinococcus multilocularis cpg binding protein 0.003 0.0245 0.1068
Loa Loa (eye worm) hypothetical protein 0.0031 0.0258 0.1107
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.066 0.2861
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2297 1
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0058 0.0135
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0258 0.1107
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0267 0.0397
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.006 0.0566 0.2465
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.0166
Toxoplasma gondii sugar transporter ST3 0.0031 0.0258 0.0383
Schistosoma mansoni smad1 5 8 and 0.0008 0.0014 0.0061
Trichomonas vaginalis esterase, putative 0.0037 0.0321 0.138
Plasmodium falciparum calcium-dependent protein kinase 5 0.0068 0.0657 0.0653
Schistosoma mansoni glucose transport protein 0.022 0.2297 1
Brugia malayi Cell death protein 3 precursor 0.0062 0.0593 0.2565
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0258 1
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0077 0.0754 0.1131
Brugia malayi hypothetical protein 0.0031 0.0258 0.1107
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0058 0.0451
Trypanosoma cruzi hexose transporter, putative 0.0068 0.066 0.5516
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0058 0.0451
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0321 0.1153
Schistosoma mansoni sugar transporter 0.0031 0.0258 0.1124
Trypanosoma cruzi sugar transporter, putative 0.0031 0.0258 0.2134

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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