Detailed information for compound 712845

Basic information

Technical information
  • TDR Targets ID: 712845
  • Name: methyl 1-(2-aminophenyl)sulfonylpyrrolidine-2 -carboxylate
  • MW: 284.331 | Formula: C12H16N2O4S
  • H donors: 1 H acceptors: 3 LogP: 1.38 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COC(=O)C1CCCN1S(=O)(=O)c1ccccc1N
  • InChi: 1S/C12H16N2O4S/c1-18-12(15)10-6-4-8-14(10)19(16,17)11-7-3-2-5-9(11)13/h2-3,5,7,10H,4,6,8,13H2,1H3
  • InChiKey: MSRAJCZQZJXDGV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(2-aminophenyl)sulfonyl-2-pyrrolidinecarboxylic acid methyl ester
  • 1-(2-aminophenyl)sulfonylpyrrolidine-2-carboxylic acid methyl ester
  • BAS 13090458
  • A3476/0147409
  • 1-(2-Amino-benzenesulfonyl)-pyrrolidine-2-carboxylic acid methyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0058 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0038 0.0128 0.0149
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.1804
Schistosoma mansoni biogenic amine receptor 0.0083 0.0404 0.0982
Schistosoma mansoni biogenic amine receptor 0.0083 0.0404 0.0982
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0083 0.0404 0.0982
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0025 0.0047 0.0049
Onchocerca volvulus 0.0083 0.0404 0.0477
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0128 0.0146
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0031 0.0085 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0083 0.0404 0.0982
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0025 0.0047 0.0053
Echinococcus multilocularis FTZ F1 alpha 0.0038 0.0128 0.0124
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052
Schistosoma mansoni single-minded 0.003 0.0077 0.0176
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0304 0.1753 0.1751
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0005 0.0002
Brugia malayi nuclear receptor NHR-88 0.0038 0.0128 0.0146
Loa Loa (eye worm) hypothetical protein 0.0101 0.051 0.0606
Onchocerca volvulus Bile acid receptor homolog 0.0038 0.0128 0.0146
Echinococcus multilocularis fmrfamide receptor 0.0083 0.0404 0.0401
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0083 0.0404 0.0479
Onchocerca volvulus Huntingtin homolog 0.0121 0.0636 0.0755
Echinococcus multilocularis musashi 0.0043 0.0159 0.0156
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0404 0.0982
Schistosoma mansoni hypothetical protein 0.0032 0.0091 0.021
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.003 0.0082 0.0079
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Brugia malayi Cation transporter family protein 0.0168 0.0919 0.1094
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0083 0.0404 0.0401
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0083 0.0404 0.0401
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Schistosoma mansoni nAChR subunit 0.0168 0.0919 0.2252
Entamoeba histolytica hypothetical protein 0.0093 0.0464 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0017 0.2943
Echinococcus granulosus sterol regulatory element binding protein 0.0023 0.0036 0.0039
Brugia malayi Kelch motif family protein 0.0038 0.0128 0.0147
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0148
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Onchocerca volvulus 0.0083 0.0404 0.0477
Entamoeba histolytica hypothetical protein 0.0038 0.0128 0.2559
Trichomonas vaginalis glucosylceramidase, putative 0.0097 0.049 0.6058
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0083 0.0404 0.0479
Schistosoma mansoni amine GPCR 0.0083 0.0404 0.0982
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0168 0.0919 0.0916
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Loa Loa (eye worm) hypothetical protein 0.0028 0.0067 0.0076
Trichomonas vaginalis glucosylceramidase, putative 0.0103 0.0522 0.6463
Leishmania major aldo-keto reductase-like protein 0.0025 0.0047 0.4708
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0026 0.0058 1
Schistosoma mansoni thyroid hormone receptor 0.0102 0.0522 0.1273
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis survival motor neuron protein 1 0.0264 0.1505 0.1502
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.1804
Loa Loa (eye worm) nuclear receptor NHR-67 0.0018 0.0005 0.0002
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0035 0.011 0.1246
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0083 0.0404 0.0477
Schistosoma mansoni retinoic acid receptor RXR 0.0038 0.0128 0.0301
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Brugia malayi Dopamine receptor 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Schistosoma mansoni hypothetical protein 0.0083 0.0404 0.0982
Loa Loa (eye worm) neuropeptide F receptor 0.0083 0.0404 0.0479
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis nuclear receptor nhr 48 0.0018 0.0005 0.0002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Brugia malayi RE15519p 0.0083 0.0404 0.0477
Giardia lamblia Kinase, CMGC MAPK 0.0031 0.0085 1
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0023 0.0036 0.0038
Echinococcus granulosus FTZ F1 alpha 0.0038 0.0128 0.0149
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0316 0.0372
Onchocerca volvulus 0.0025 0.0047 0.0049
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0024 0.0045 0.005
Onchocerca volvulus 0.0022 0.003 0.0029
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0038 0.0128 0.0301
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0083 0.0404 0.0983
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0083 0.0404 0.0477
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0404 0.048
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0404 0.0401
Schistosoma mansoni biogenic amine receptor 0.0083 0.0404 0.0982
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Echinococcus multilocularis nAChR subunit 0.0093 0.0464 0.0461
Echinococcus granulosus neuropeptide receptor 0.0083 0.0404 0.048
Trichomonas vaginalis glucosylceramidase, putative 0.0103 0.0522 0.6463
Brugia malayi Melatonin receptor type 1A 0.0083 0.0404 0.0477
Echinococcus multilocularis allatostatin A receptor 0.0083 0.0404 0.0401
Echinococcus multilocularis aldo keto reductase 0.0025 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Echinococcus granulosus g protein coupled receptor 0.0083 0.0404 0.048
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Echinococcus multilocularis geminin 0.0185 0.1023 0.102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0038 0.0128 0.0148
Loa Loa (eye worm) LGC-31 protein 0.0168 0.0919 0.1096
Schistosoma mansoni amine GPCR 0.0083 0.0404 0.0982
Onchocerca volvulus 0.0168 0.0919 0.1094
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0128 0.0149
Mycobacterium leprae PROBABLE OXIDOREDUCTASE 0.0025 0.0047 0.8075
Onchocerca volvulus 0.0168 0.0919 0.1094
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0083 0.0404 0.0479
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0168 0.0919 0.0916
Brugia malayi Integrin beta pat-3 precursor 0.025 0.142 0.1694
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0031 0.0085 1
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0168 0.0919 0.2252
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.003 0.0082 0.0094
Echinococcus multilocularis neuropeptides capa receptor 0.0083 0.0404 0.0401
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0168 0.0919 0.0916
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0083 0.0404 0.0479
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0016
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0038 0.0128 0.0301
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0083 0.0404 0.0401
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0168 0.0919 0.2252
Echinococcus granulosus neuropeptides capa receptor 0.0083 0.0404 0.048
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0024 0.0046 1
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0026 0.0058 1
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0083 0.0404 0.0401
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0091 0.0087
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0021 0.0023 0.0024
Echinococcus multilocularis Niemann Pick C1 protein 0.0076 0.0361 0.0358
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0083 0.0404 0.048
Onchocerca volvulus Huntingtin homolog 0.0121 0.0636 0.0755
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0168 0.0919 0.0916
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0404 0.0401
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0168 0.0919 0.1094
Loa Loa (eye worm) neuropeptide F receptor 0.0083 0.0404 0.0479
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0018 0.0005 0.0002
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0801 1
Echinococcus multilocularis expressed conserved protein 0.005 0.0202 0.0198
Echinococcus granulosus histone acetyltransferase KAT2B 0.0024 0.0046 0.0051
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0404 0.0982
Schistosoma mansoni steroid hormone receptor ad4bp 0.0038 0.0128 0.0301
Echinococcus multilocularis neuropeptide receptor 0.0127 0.0674 0.0671
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0083 0.0404 0.048
Mycobacterium leprae Conserved hypothetical protein 0.0017 0.0003 0.0547
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0026 0.0058 1
Echinococcus granulosus GPCR family 2 0.0032 0.0091 0.0105
Onchocerca volvulus 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Trichomonas vaginalis inositol monophosphatase, putative 0.0019 0.0012 0.0002
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0404 0.048
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.1804
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0148
Brugia malayi MH2 domain containing protein 0.0118 0.0617 0.0733
Schistosoma mansoni acetylcholine receptor-related 0.0075 0.0351 0.0853
Echinococcus granulosus aldo keto reductase 0.0025 0.0047 0.0052
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0404 0.048
Schistosoma mansoni nAChR subunit 0.0168 0.0919 0.2252
Echinococcus multilocularis transfer RNA-Lys 0.0022 0.003 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0038 0.0128 0.0146
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0058 0.6224
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0801 1
Entamoeba histolytica hypothetical protein 0.0038 0.0128 0.2559
Echinococcus multilocularis fmrfamide receptor 0.0083 0.0404 0.0401
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0168 0.0919 0.1097
Schistosoma mansoni amine GPCR 0.0083 0.0404 0.0982
Brugia malayi bHLH-PAS transcription factor 0.0022 0.003 0.0029
Brugia malayi hypothetical protein 0.002 0.0019 0.0016
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0318 0.1835 0.2193
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Onchocerca volvulus 0.0025 0.0047 0.0049
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0058 0.0063
Trichomonas vaginalis bromodomain-containing protein, putative 0.0024 0.0046 0.0429
Echinococcus granulosus G protein coupled receptor 139 0.0083 0.0404 0.048
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0404 0.048
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0038 0.0128 0.0146
Loa Loa (eye worm) hypothetical protein 0.0023 0.0036 0.0038
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0801 1
Brugia malayi cytoplasmic intermediate filament protein 0.0023 0.0037 0.0038
Schistosoma mansoni coup transcription factor 0.0038 0.0128 0.0301
Echinococcus multilocularis protein patched 0.0023 0.0036 0.0033
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0053 0.0217 0.0522
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Schistosoma mansoni RAR-like nuclear receptor 0.0038 0.0128 0.0301
Onchocerca volvulus 0.0168 0.0919 0.1094
Echinococcus multilocularis inhibitor of apoptosis protein 0.038 0.2216 0.2213
Brugia malayi Steroid receptor seven-up type 2 0.0038 0.0128 0.0146
Echinococcus granulosus serotonin receptor 0.0083 0.0404 0.048
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0019 0.0012 0.5
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0031 0.0085 1
Echinococcus multilocularis lamin 0.0043 0.0159 0.0156
Brugia malayi sulfakinin receptor protein 0.0083 0.0404 0.0477
Onchocerca volvulus Protein ultraspiracle homolog 0.0038 0.0128 0.0146
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0058 1
Echinococcus granulosus integrin beta 2 0.0185 0.1025 0.1224
Onchocerca volvulus 0.0083 0.0404 0.0477
Mycobacterium ulcerans oxidoreductase 0.0025 0.0047 0.7564
Toxoplasma gondii aldose reductase, putative 0.0025 0.0047 0.1685
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0038 0.0128 0.0125
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0083 0.0404 0.0401
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Onchocerca volvulus 0.0093 0.0464 0.0549
Loa Loa (eye worm) MH2 domain-containing protein 0.0118 0.0617 0.0735
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Onchocerca volvulus 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0083 0.0404 0.0401
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0054 0.0226 0.0544
Onchocerca volvulus 0.0038 0.0128 0.0146
Loa Loa (eye worm) oxidoreductase 0.0025 0.0047 0.0051
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Onchocerca volvulus 0.0083 0.0404 0.0477
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Loa Loa (eye worm) calpain family protein 1 0.0029 0.0073 0.0083
Loa Loa (eye worm) oxidoreductase 0.0025 0.0047 0.0051
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0083 0.0404 0.0401
Echinococcus multilocularis somatostatin receptor 0.0083 0.0404 0.0401
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0168 0.0919 0.1094
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0083 0.0404 0.0477
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0038 0.0128 0.0146
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0058 0.0063
Echinococcus granulosus microtubule associated protein 2 0.0683 0.4061 0.4861
Loa Loa (eye worm) TYRA-2 protein 0.0083 0.0404 0.0479
Chlamydia trachomatis methionine--tRNA ligase 0.0046 0.0174 1
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0021 0.0023 0.002
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Brugia malayi hypothetical protein 0.0121 0.0636 0.0755
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0038 0.0128 0.0149
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Giardia lamblia Aldose reductase 0.0025 0.0047 0.2547
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0058 0.6224
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.002 0.0019 0.0032
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0083 0.0404 0.0982
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0018 0.0005 0.0003
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0038 0.0128 0.0301
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Echinococcus granulosus Solute carrier family 22 5 0.0531 0.3137 0.3753
Trichomonas vaginalis aldo/keto reductase, putative 0.0025 0.0047 0.044
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0404 0.0401
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Echinococcus granulosus neuropeptide receptor 0.0127 0.0674 0.0803
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0351 0.0414
Onchocerca volvulus 0.0025 0.0047 0.0049
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0065 0.0291 0.0344
Entamoeba histolytica hypothetical protein 0.0038 0.0128 0.2559
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Schistosoma mansoni aldo-keto reductase 0.0025 0.0047 0.0101
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Onchocerca volvulus 0.0075 0.0351 0.0414
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0404 0.0401
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0075 0.0351 0.0416
Schistosoma mansoni adenoreceptor 0.0083 0.0404 0.0982
Onchocerca volvulus 0.002 0.002 0.0018
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Loa Loa (eye worm) hypoxia-induced factor 1 0.0092 0.0455 0.054
Loa Loa (eye worm) hypothetical protein 0.0029 0.0073 0.0083
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0404 0.048
Onchocerca volvulus 0.0083 0.0404 0.0477
Brugia malayi putative neuropeptide receptor NPR1 0.0083 0.0404 0.0477
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Echinococcus granulosus potassium voltage gated channel subfamily H 0.002 0.002 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0038 0.0128 0.0148
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0168 0.0919 0.1096
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0083 0.0404 0.0401
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0168 0.0919 0.2252
Echinococcus granulosus methionyl tRNA synthetase cytoplasmic 0.0046 0.0174 0.0205
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0075 0.0351 0.0348
Brugia malayi Intermediate filament tail domain containing protein 0.0043 0.0159 0.0184
Echinococcus multilocularis aldo keto reductase 0.0025 0.0047 0.0044
Schistosoma mansoni lipoxygenase 0.0072 0.0334 0.081
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Brugia malayi Cytochrome P450 family protein 0.0039 0.0135 0.0155
Brugia malayi hypothetical protein 0.0038 0.0128 0.0147
Echinococcus granulosus neuropeptides capa receptor 0.0083 0.0404 0.048
Mycobacterium tuberculosis Probable oxidoreductase 0.0025 0.0047 0.8075
Loa Loa (eye worm) hypothetical protein 0.1386 0.8352 1
Echinococcus granulosus neuropeptide receptor A26 0.0083 0.0404 0.048
Loa Loa (eye worm) hypothetical protein 0.0264 0.1505 0.1798
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0168 0.0919 0.1094
Schistosoma mansoni hypothetical protein 0.0024 0.0045 0.0097
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus sex peptide receptor 0.0083 0.0404 0.048
Echinococcus granulosus geminin 0.0185 0.1023 0.1222
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0168 0.0919 0.1097
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0404 0.048
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Echinococcus multilocularis g-protein coupled receptor 0.0083 0.0404 0.0401
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0025 0.0047 0.044
Loa Loa (eye worm) calpain family protein 1 0.002 0.002 0.002
Schistosoma mansoni neurotransmitter gated ion channel 0.0075 0.0351 0.0853
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0038 0.0128 0.0146
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0801 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0058 1
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0168 0.0919 0.1094
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0168 0.0919 0.1094
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0038 0.0128 0.0124
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0026 0.0058 1
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0019 0.0012 0.0002
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0168 0.0919 0.0916
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0168 0.0919 0.0916
Echinococcus multilocularis mitogen activated protein kinase 3 0.0031 0.0085 0.0082
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0058 0.101
Schistosoma mansoni thyroid hormone receptor 0.0102 0.0522 0.1273
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Loa Loa (eye worm) apoptosis regulator protein 0.0024 0.0045 0.0049
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0031 0.0085 1
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0075 0.0351 0.0417
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0038 0.0128 0.0148
Echinococcus granulosus mitogen activated protein kinase 3 0.0031 0.0085 0.0099
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0168 0.0919 0.1096
Brugia malayi calpain family protein 1 0.0029 0.0073 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Brugia malayi Niemann-Pick C1 protein precursor 0.0053 0.0221 0.0259
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0093 0.0464 0.0549
Echinococcus granulosus nAChR subunit 0.0093 0.0464 0.0552
Loa Loa (eye worm) steroid hormone receptor 0.0038 0.0128 0.0148
Trypanosoma brucei protein kinase, putative 0.0031 0.0085 1
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0031 0.0085 0.3578
Mycobacterium ulcerans fatty-acid-CoA ligase 0.002 0.0017 0.107
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0025 0.0047 0.0103
Schistosoma mansoni acetylcholine receptor subunit beta 0.0075 0.0351 0.0853
Loa Loa (eye worm) acetyltransferase 0.0083 0.0404 0.048
Schistosoma mansoni nAChR subunit 0.0168 0.0919 0.2252
Schistosoma mansoni lipoxygenase 0.005 0.0202 0.0485
Echinococcus granulosus g protein coupled receptor 0.0083 0.0404 0.048
Trichomonas vaginalis glucosylceramidase, putative 0.0097 0.049 0.6058
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0128 0.0146
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0149
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0029 0.0073 0.0166
Onchocerca volvulus 0.0083 0.0404 0.0477
Echinococcus multilocularis tumor protein p63 0.0713 0.4247 0.4245
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0031 0.0085 0.0098
Schistosoma mansoni lamin 0.0043 0.0159 0.0379
Echinococcus multilocularis dro:myosuppressin receptor 0.0083 0.0404 0.0401
Schistosoma mansoni nAChR subunit 0.0168 0.0919 0.2252
Brugia malayi intermediate filament protein 0.0043 0.0159 0.0184
Echinococcus granulosus tm gpcr rhodopsin 0.0083 0.0404 0.048
Schistosoma mansoni methionine-tRNA synthetase 0.0046 0.0174 0.0416
Schistosoma mansoni hypothetical protein 0.0022 0.0031 0.0063
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus aldo keto reductase 0.0025 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis GPCR, family 2 0.0032 0.0091 0.0087
Schistosoma mansoni neuropeptide receptor 0.0083 0.0404 0.0982
Brugia malayi PAS domain containing protein 0.003 0.0077 0.0086
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0025 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0032 0.0091 0.0104
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Trichomonas vaginalis glucosylceramidase, putative 0.0097 0.049 0.6058
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0083 0.0404 0.0982
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0075 0.0351 0.0414
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0093 0.0464 0.0549
Schistosoma mansoni lamin 0.0043 0.0159 0.0379
Schistosoma mansoni biogenic amine (5HT) receptor 0.0083 0.0404 0.0982
Echinococcus granulosus Niemann Pick C1 protein 0.0076 0.0361 0.0428
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0024 0.0045 0.0042
Schistosoma mansoni inhibitor of apoptosis protein 0.038 0.2216 0.5449
Loa Loa (eye worm) hypothetical protein 0.0069 0.0316 0.0374
Onchocerca volvulus 0.0083 0.0404 0.0477
Brugia malayi neuropeptide F receptor 0.0083 0.0404 0.0477
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0038 0.0128 0.0301
Schistosoma mansoni hypothetical protein 0.0022 0.0031 0.0063
Echinococcus multilocularis neuropeptide Y receptor 0.0083 0.0404 0.0401
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.0085 0.0931
Schistosoma mansoni neurotransmitter gated ion channel 0.0093 0.0464 0.1131
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0083 0.0404 0.0982
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0038 0.0128 0.0149
Leishmania major prostaglandin f2-alpha synthase/D-arabinose dehydrogenase 0.0025 0.0047 0.4708
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0025 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0016
Schistosoma mansoni inositol monophosphatase 0.0019 0.0012 0.0016
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0075 0.0351 0.0416
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0075 0.0351 0.0414
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Trypanosoma brucei prostaglandin f synthase 0.0025 0.0047 0.4708
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0025 0.0047 0.0053
Loa Loa (eye worm) intermediate filament protein 0.0043 0.0159 0.0186
Trichomonas vaginalis glucosylceramidase, putative 0.0097 0.049 0.6058
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0019 0.0016
Toxoplasma gondii melibiase subfamily protein 0.0053 0.0217 1
Brugia malayi putative neuropeptide receptor 0.0083 0.0404 0.0477
Brugia malayi hypothetical protein 0.0099 0.0502 0.0595
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Echinococcus granulosus single minded 2 0.0024 0.0041 0.0046
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.038 0.2216 0.5449
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0083 0.0404 0.048
Schistosoma mansoni histamine h1 receptor 0.0083 0.0404 0.0982
Schistosoma mansoni serine/threonine protein kinase 0.0031 0.0085 0.0197
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0404 0.0401
Echinococcus granulosus g protein coupled receptor 0.0083 0.0404 0.048
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0038 0.0128 0.0301
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Schistosoma mansoni nAChR subunit 0.0168 0.0919 0.2252
Echinococcus granulosus hypothetical protein 0.0083 0.0404 0.048
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0801 1
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0023 0.0037 0.004
Loa Loa (eye worm) oxidoreductase 0.0025 0.0047 0.0051
Echinococcus granulosus orexin receptor type 2 0.0083 0.0404 0.048
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0168 0.0919 0.1094
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0038 0.0128 0.0124
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0083 0.0404 0.0401
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0038 0.0128 0.0146
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Brugia malayi hypothetical protein 0.0075 0.0351 0.0414
Brugia malayi ORL1-like opioid receptor 0.0083 0.0404 0.0477
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0038 0.0128 0.0301
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0225 0.0263
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0072 0.0334 0.0396
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0168 0.0919 0.1097
Brugia malayi neuropeptide F receptor 0.0083 0.0404 0.0477
Brugia malayi Inositol-1 0.0019 0.0012 0.0008
Schistosoma mansoni neuropeptide f receptor 76f 0.0083 0.0404 0.0982
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Loa Loa (eye worm) hypothetical protein 0.0024 0.0045 0.0049
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0031 0.0085 1
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0168 0.0919 0.1094
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0168 0.0919 0.0916
Schistosoma mansoni hypothetical protein 0.0032 0.0091 0.021
Schistosoma mansoni intermediate filament proteins 0.0043 0.0159 0.0379
Onchocerca volvulus Neuropeptide F receptor homolog 0.0083 0.0404 0.0477
Echinococcus granulosus neuropeptide Y receptor 0.0083 0.0404 0.048
Echinococcus multilocularis ecdysone induced protein 78C 0.0038 0.0128 0.0124
Loa Loa (eye worm) hypothetical protein 0.0042 0.0154 0.0181
Brugia malayi ecdysteroid receptor 0.0038 0.0128 0.0146
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0025 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Loa Loa (eye worm) nuclear hormone receptor 0.0018 0.0005 0.0002
Echinococcus multilocularis glycine receptor subunit beta 0.0168 0.0919 0.0916
Loa Loa (eye worm) multisynthetase complex auxiliary component p43 0.0046 0.0176 0.0206
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Loa Loa (eye worm) hypothetical protein 0.002 0.002 0.002
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0083 0.0404 0.0982
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0168 0.0919 0.1097
Loa Loa (eye worm) DR-78 0.0018 0.0005 0.0002
Brugia malayi Nuclear hormone receptor-like 1 0.0038 0.0128 0.0146
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Onchocerca volvulus 0.0104 0.0533 0.0632
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0128 0.0124
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0404 0.048
Trichomonas vaginalis glucosylceramidase, putative 0.0148 0.0801 1
Brugia malayi hypothetical protein 0.0075 0.0351 0.0414
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0026 0.0058 1
Schistosoma mansoni hypothetical protein 0.0032 0.0091 0.021
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0168 0.0919 0.1097
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0168 0.0919 0.0916
Echinococcus granulosus fmrfamide receptor 0.0083 0.0404 0.048
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0065 0.0291 0.0288
Leishmania major prostaglandin f synthase, putative 0.0025 0.0047 0.4708
Echinococcus granulosus glycine receptor subunit alpha 1 0.0168 0.0919 0.1097
Trichomonas vaginalis conserved hypothetical protein 0.0023 0.0036 0.0303
Echinococcus granulosus glycine receptor subunit beta 0.0168 0.0919 0.1097
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0148 0.0801 0.0953
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus granulosus expressed conserved protein 0.005 0.0202 0.0238
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.051 0.0606
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0083 0.0404 0.0982
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0038 0.0128 0.0149
Schistosoma mansoni hypothetical protein 0.0024 0.0045 0.0097
Echinococcus multilocularis orexin receptor type 2 0.0083 0.0404 0.0401
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.0085 0.0931
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus nuclear receptor nhr 48 0.0018 0.0005 0.0003
Echinococcus multilocularis Niemann Pick C1 protein 0.0053 0.0221 0.0218
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.051 0.0604
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0083 0.0404 0.0401
Schistosoma mansoni hypothetical protein 0.0054 0.0225 0.054
Loa Loa (eye worm) transcription factor SMAD2 0.0118 0.0617 0.0735
Schistosoma mansoni apoptosis regulator bax 0.0024 0.0045 0.0097
Brugia malayi Tachykinin-like peptides receptor 99D 0.0083 0.0404 0.0477
Onchocerca volvulus 0.0054 0.0225 0.0263
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.1386 0.8352 1
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Schistosoma mansoni opsin-like receptor 0.0083 0.0404 0.0982
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0053 0.0217 0.0256
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0075 0.0351 0.0348
Loa Loa (eye worm) hypothetical protein 0.0029 0.0073 0.0083
Echinococcus multilocularis aldo keto reductase 0.0025 0.0047 0.0044
Schistosoma mansoni neuropeptide F-like receptor 0.0083 0.0404 0.0982
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Schistosoma mansoni hypothetical protein 0.0032 0.0091 0.021
Brugia malayi CHE-14 protein 0.0023 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0148
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0083 0.0404 0.0477
Schistosoma mansoni amine GPCR 0.0083 0.0404 0.0982
Schistosoma mansoni hypothetical protein 0.0069 0.0316 0.0765
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0148 0.0801 0.0955
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0035 0.011 0.0258
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus granulosus biogenic amine 5HT receptor 0.0441 0.2586 0.3094
Echinococcus multilocularis calpain A 0.003 0.0082 0.0079
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0053 0.0221 0.0261
Schistosoma mansoni hypothetical protein 0.0022 0.0031 0.0063
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0025 0.0047 0.044
Leishmania major 4-coumarate:coa ligase-like protein 0.0026 0.0058 0.6224
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0043 0.0159 0.0186
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0019 0.001 0.1804
Brugia malayi Melibiase family protein 0.0035 0.011 0.0126
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0083 0.0404 0.0982
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0005 0.0003
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0533 0.1301
Echinococcus granulosus intermediate filament protein 0.0043 0.0159 0.0187
Onchocerca volvulus 0.0093 0.0464 0.0549
Trypanosoma cruzi aldo-keto reductase 0.0025 0.0047 0.4708
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0093 0.0464 0.1131
Brugia malayi Dopamine receptor protein 2 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Leishmania major aldehyde reductase, putative,oxidoreductase, putative 0.0025 0.0047 0.4708
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0168 0.0919 0.1097
Loa Loa (eye worm) hypothetical protein 0.0099 0.0502 0.0597
Loa Loa (eye worm) hypothetical protein 0.0026 0.0058 0.0065
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Brugia malayi photoreceptor-specific nuclear receptor 0.0038 0.0128 0.0146
Brugia malayi excitatory GABA receptor EXP-1A 0.0168 0.0919 0.1094
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0038 0.0128 0.0146
Echinococcus multilocularis methionyl tRNA synthetase, cytoplasmic 0.0046 0.0174 0.0171
Echinococcus granulosus calpain A 0.003 0.0082 0.0094
Onchocerca volvulus Putative nachr subunit 0.0168 0.0919 0.1094
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0404 0.0401
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0025 0.0047 0.0049
Echinococcus granulosus ecdysone induced protein 78C 0.0038 0.0128 0.0149
Echinococcus multilocularis neuropeptides capa receptor 0.0083 0.0404 0.0401
Entamoeba histolytica acyl-CoA synthetase, putative 0.0026 0.0058 0.101
Loa Loa (eye worm) oxidoreductase 0.0025 0.0047 0.0051
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0168 0.0919 0.1094
Schistosoma mansoni nAChR subunit 0.0168 0.0919 0.2252
Loa Loa (eye worm) hypothetical protein 0.002 0.0017 0.0016
Echinococcus multilocularis g protein coupled receptor 0.0083 0.0404 0.0401
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0024 0.0045 0.0097
Schistosoma mansoni hypothetical protein 0.038 0.2216 0.5449
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0083 0.0404 0.048
Loa Loa (eye worm) hypothetical protein 0.0441 0.2586 0.3094
Onchocerca volvulus 0.0083 0.0404 0.0477
Onchocerca volvulus 0.0083 0.0404 0.0477
Echinococcus multilocularis sterol regulatory element binding protein 0.0023 0.0036 0.0033
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0168 0.0919 0.2252
Entamoeba histolytica aldose reductase, putative 0.0025 0.0047 0.0764
Trichomonas vaginalis dihydrodiol dehydrogenase, putative 0.0025 0.0047 0.044
Echinococcus granulosus neuropeptide s receptor 0.0083 0.0404 0.048
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0168 0.0919 0.1094
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0018 0.0005 0.0002
Echinococcus multilocularis neuropeptide s receptor 0.0083 0.0404 0.0401
Schistosoma mansoni neuropeptide receptor 0.0127 0.0674 0.1648
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0168 0.0919 0.1096
Echinococcus multilocularis mitogen activated protein kinase 0.0031 0.0085 0.0082
Trichomonas vaginalis glucosylceramidase, putative 0.0097 0.049 0.6058
Schistosoma mansoni opsin-like receptor 0.0083 0.0404 0.0982
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0168 0.0919 0.0916
Onchocerca volvulus 0.0025 0.0047 0.0049
Onchocerca volvulus 0.0025 0.0047 0.0049
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0168 0.0919 0.1094
Brugia malayi Serotonin receptor 0.0083 0.0404 0.0477
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0093 0.0464 0.0549
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0083 0.0404 0.0401
Brugia malayi calpain family protein 1 0.0029 0.0073 0.0081
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0404 0.0401
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0038 0.0128 0.0148
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0148
Echinococcus multilocularis aldo keto reductase 0.0025 0.0047 0.0044
Trichomonas vaginalis aldo/keto reductase, putative 0.0025 0.0047 0.044
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Echinococcus granulosus aldo keto reductase 0.0025 0.0047 0.0052
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0025 0.0047 0.0044
Brugia malayi G protein-coupled receptor F59B2.13 0.0083 0.0404 0.0477
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0404 0.048
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0128 0.0146
Brugia malayi hypothetical protein 0.0264 0.1505 0.1797
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0083 0.0404 0.0401
Loa Loa (eye worm) hypothetical protein 0.0104 0.0533 0.0634
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Loa Loa (eye worm) G-protein coupled receptor 0.0083 0.0404 0.0479
Onchocerca volvulus 0.0075 0.0351 0.0414
Echinococcus granulosus glycine receptor subunit alpha 1 0.0168 0.0919 0.1097
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0024 0.0045 0.0047
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Schistosoma mansoni integrin beta subunit 0.0147 0.0793 0.1942
Brugia malayi steroid hormone receptor 0.0038 0.0128 0.0146
Loa Loa (eye worm) hypothetical protein 0.0026 0.0058 0.0065
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Brugia malayi Dopamine receptor protein 1 0.0083 0.0404 0.0477
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0351 0.0414
Loa Loa (eye worm) GABA receptor subunit 0.0093 0.0464 0.0551
Echinococcus multilocularis serotonin receptor 0.0441 0.2586 0.2584
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.003 0.0082 0.0188
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Schistosoma mansoni survival motor neuron protein 0.0054 0.0225 0.054
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0075 0.0351 0.0417
Loa Loa (eye worm) hypothetical protein 0.0046 0.0174 0.0204
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052
Onchocerca volvulus 0.0026 0.0058 0.0063
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0091 0.0105
Entamoeba histolytica methionyl-tRNA synthetase, putative 0.0053 0.022 0.4602
Brugia malayi nuclear hormone receptor 0.0038 0.0128 0.0146
Loa Loa (eye worm) hypothetical protein 0.0121 0.0636 0.0757
Brugia malayi hypothetical protein 0.0038 0.0128 0.0147
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0072 0.0334 0.0331
Schistosoma mansoni hypothetical protein 0.0083 0.0404 0.0982
Schistosoma mansoni patched 1 0.0023 0.0036 0.0075
Schistosoma mansoni hypothetical protein 0.0022 0.0031 0.0063
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0038 0.0128 0.0124
Echinococcus granulosus 7tm_1 domain containing protein 0.0083 0.0404 0.048
Brugia malayi AMP-binding enzyme family protein 0.0026 0.0058 0.0063
Schistosoma mansoni hypothetical protein 0.0024 0.0045 0.0097
Schistosoma mansoni nAChR subunit 0.0168 0.0919 0.2252
Echinococcus multilocularis inositol monophosphatase 1 0.0019 0.0012 0.0009
Brugia malayi follicle stimulating hormone receptor 0.0318 0.1835 0.2191
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0038 0.0128 0.0146
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0031 0.0085 1
Echinococcus granulosus inhibitor of apoptosis protein 0.038 0.2216 0.265
Trichomonas vaginalis glucosylceramidase, putative 0.0097 0.049 0.6058
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Schistosoma mansoni myosin xvIII 0.0083 0.0404 0.0982
Onchocerca volvulus 0.038 0.2216 0.2648
Loa Loa (eye worm) G-protein coupled receptor 0.0083 0.0404 0.0479
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0168 0.0919 0.1094
Brugia malayi larval opioid receptor 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Onchocerca volvulus 0.0083 0.0404 0.0477
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0168 0.0919 0.1094
Schistosoma mansoni neurotransmitter gated ion channel 0.0075 0.0351 0.0853
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0038 0.0128 0.0146
Brugia malayi hypothetical protein 0.002 0.0019 0.0016
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Entamoeba histolytica aldose reductase, putative 0.0025 0.0047 0.0764
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0053 0.0217 0.0522
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0083 0.0404 0.0477
Brugia malayi G-protein coupled receptor 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Onchocerca volvulus 0.0083 0.0404 0.0477
Schistosoma mansoni transcription factor LCR-F1 0.0038 0.0128 0.0302
Schistosoma mansoni alpha-1 adrenergic receptor 0.0083 0.0404 0.0982
Echinococcus granulosus neuropeptide Y receptor 0.0083 0.0404 0.048
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.1386 0.8352 0.8352
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0031 0.0064
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0075 0.0351 0.0348
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0024 0.0046 0.1645
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0038 0.0128 0.0124
Echinococcus granulosus tumor protein p63 0.0713 0.4247 0.5083
Echinococcus multilocularis nAChR subunit 0.0168 0.0919 0.0916
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0026 0.0058 1
Brugia malayi oxidoreductase, aldo/keto reductase family protein 0.0025 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0148
Schistosoma mansoni growth hormone secretagogue receptor 0.0083 0.0404 0.0982
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0038 0.0128 0.0148
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0168 0.0919 0.1094
Onchocerca volvulus 0.0083 0.0404 0.0477
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0168 0.0919 0.1097
Brugia malayi GnHR receptor homolog 0.0083 0.0404 0.0477
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.002 0.0019 0.0018
Entamoeba histolytica acetyltransferase, GNAT family 0.0022 0.0033 0.0471
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Echinococcus granulosus mitogen activated protein kinase 0.0031 0.0085 0.0099
Loa Loa (eye worm) integrin beta-2 0.025 0.142 0.1696
Schistosoma mansoni neuropeptide F-like receptor 0.0083 0.0404 0.0982
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0091 0.0102
Brugia malayi hypothetical protein 0.0075 0.0351 0.0414
Echinococcus multilocularis protein dispatched 1 0.0026 0.0056 0.0052
Brugia malayi hypothetical protein 0.0075 0.0351 0.0414
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0083 0.0404 0.0982
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0148
Schistosoma mansoni nAChR subunit 0.0075 0.0351 0.0853
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus granulosus survival motor neuron protein 1 0.0264 0.1505 0.1799
Loa Loa (eye worm) inositol-1 0.0019 0.0012 0.001
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0168 0.0919 0.0916
Loa Loa (eye worm) cytochrome P450 family protein 0.0039 0.0135 0.0157
Brugia malayi AKH receptor 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0051
Echinococcus granulosus glycine receptor subunit alpha 1 0.0168 0.0919 0.1097
Loa Loa (eye worm) ACC-1 protein 0.0168 0.0919 0.1096
Onchocerca volvulus 0.0168 0.0919 0.1094
Echinococcus multilocularis calpain family protein 1, d 0.002 0.002 0.0017
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0168 0.0919 0.1094
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0025 0.0047 0.0103
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0148
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0018 0.0005 0.0002
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0053 0.0217 0.0214
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0018 0.0005 0.0002
Schistosoma mansoni nuclear hormone receptor 0.0038 0.0128 0.0301
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0168 0.0919 0.2252
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0083 0.0404 0.0982
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0083 0.0404 0.0982
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.002 0.002 0.002
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0038 0.0128 0.0149
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0404 0.0401
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.003 0.0082 0.0188
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Plasmodium falciparum histone acetyltransferase GCN5 0.0022 0.0033 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0038 0.0128 0.0149
Brugia malayi hypoxia-induced factor 1 0.0092 0.0455 0.0538
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0053 0.0221 0.4627
Echinococcus granulosus allatostatin A receptor 0.0083 0.0404 0.048
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0053 0.0217 0.0214
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0031 0.0064
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Giardia lamblia Aldose reductase 0.0025 0.0047 0.2547
Trypanosoma cruzi aldo/keto reductase, putative 0.0025 0.0047 0.4708
Treponema pallidum methionyl-tRNA synthetase 0.0053 0.022 0.5
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Onchocerca volvulus 0.0043 0.0159 0.0184
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.0085 0.0931
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Echinococcus granulosus Niemann Pick C1 protein 0.0053 0.0221 0.0261
Echinococcus granulosus lamin 0.0043 0.0159 0.0187
Loa Loa (eye worm) hypothetical protein 0.0043 0.0159 0.0186
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.002 0.002 0.0017
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0091 0.0104
Onchocerca volvulus 0.0083 0.0404 0.0477
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0025 0.0047 0.005
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Echinococcus granulosus dro:myosuppressin receptor 0.0083 0.0404 0.048
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0026 0.0058 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0404 0.0401
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0019 0.0032
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0083 0.0404 0.0477
Brugia malayi nuclear receptor RXR 0.002 0.0019 0.0016
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0038 0.0128 0.0149
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Schistosoma mansoni neuropeptide receptor 0.0083 0.0404 0.0982
Trypanosoma brucei aldo-keto reductase, putative 0.0025 0.0047 0.4708
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0083 0.0404 0.0982
Schistosoma mansoni biogenic amine (5HT) receptor 0.0441 0.2586 0.6363
Brugia malayi methionyl-tRNA synthetase 0.0053 0.022 0.0257
Mycobacterium ulcerans acyl-CoA synthetase 0.0026 0.0058 1
Echinococcus granulosus nAChR subunit 0.0168 0.0919 0.1097
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Loa Loa (eye worm) hypothetical protein 0.038 0.2216 0.2649
Loa Loa (eye worm) ACC-1 protein 0.0168 0.0919 0.1096
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0018 0.0005 0.0003
Echinococcus granulosus tachykinin peptides receptor 99D 0.0083 0.0404 0.048
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0075 0.0351 0.0414
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0038 0.0128 0.0124
Echinococcus granulosus biogenic amine 5HT receptor 0.0083 0.0404 0.048
Brugia malayi Serotonin receptor 0.0083 0.0404 0.0477
Loa Loa (eye worm) hypothetical protein 0.0026 0.0058 0.0065
Onchocerca volvulus 0.0083 0.0404 0.0477
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0083 0.0404 0.0401
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0168 0.0919 0.1094
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.002 0.0019 0.0018
Onchocerca volvulus 0.0043 0.0159 0.0184
Echinococcus multilocularis glycine receptor subunit beta 0.0168 0.0919 0.0916
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0024 0.0046 0.0429
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0038 0.0128 0.0148
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0168 0.0919 0.2252
Schistosoma mansoni neuropeptide receptor 0.0083 0.0404 0.0982
Schistosoma mansoni nAChR subunit 0.0075 0.0351 0.0853
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0168 0.0919 0.1094
Echinococcus multilocularis sex peptide receptor 0.0083 0.0404 0.0401
Loa Loa (eye worm) hypothetical protein 0.0035 0.011 0.0128
Echinococcus granulosus baculoviral IAP repeat containing protein 0.1386 0.8352 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0083 0.0404 0.048
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Schistosoma mansoni inositol monophosphatase 0.0019 0.0012 0.0016
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Brugia malayi MAP kinase sur-1 0.0031 0.0085 0.0096
Echinococcus multilocularis G-protein coupled receptor, putative 0.0083 0.0404 0.0401
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0053 0.0217 0.0522
Trichomonas vaginalis glucosylceramidase, putative 0.0097 0.049 0.6058
Onchocerca volvulus 0.0083 0.0404 0.0477
Schistosoma mansoni hypothetical protein 0.0083 0.0404 0.0982
Echinococcus multilocularis neuropeptide receptor A26 0.0083 0.0404 0.0401
Echinococcus multilocularis serotonin receptor 0.0441 0.2586 0.2584
Schistosoma mansoni aldo-keto reductase 0.0025 0.0047 0.0101
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Schistosoma mansoni opsin-like receptor 0.0083 0.0404 0.0982
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0091 0.0102
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0091 0.0105
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.051 0.0604
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0168 0.0919 0.1096
Loa Loa (eye worm) hypothetical protein 0.0021 0.0023 0.0023
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0038 0.0128 0.0149
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0035 0.011 0.0258
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0168 0.0919 0.1096
Loa Loa (eye worm) hypothetical protein 0.0441 0.2586 0.3094
Schistosoma mansoni microtubule-associated protein tau 0.0683 0.4061 1
Mycobacterium ulcerans putative regulatory protein 0.0022 0.003 0.3922
Schistosoma mansoni hypothetical protein 0.0083 0.0404 0.0982
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.002 0.0019 0.0015
Brugia malayi G protein-coupled receptor 0.0083 0.0404 0.0477
Schistosoma mansoni hypothetical protein 0.0185 0.1023 0.2509
Brugia malayi Cation transporter family protein 0.0168 0.0919 0.1094
Echinococcus multilocularis neuropeptide FF receptor 2 0.0083 0.0404 0.0401
Onchocerca volvulus 0.0168 0.0919 0.1094
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis integrin beta 2 0.0185 0.1025 0.1022
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0404 0.0401
Echinococcus granulosus hypothetical protein 0.0025 0.0047 0.0052
Brugia malayi hypothetical protein 0.0075 0.0351 0.0414
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0093 0.0464 0.1131
Loa Loa (eye worm) melatonin receptor type 1A 0.0083 0.0404 0.0479
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Loa Loa (eye worm) hypothetical protein 0.0038 0.0128 0.0148
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0031 0.0085 1
Onchocerca volvulus 0.0168 0.0919 0.1094
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0018 0.0005 0.0002
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0053 0.0217 0.0522
Onchocerca volvulus Glucosylceramidase homolog 0.0097 0.049 0.0581
Brugia malayi G-protein coupled receptor 0.0083 0.0404 0.0477
Echinococcus granulosus inositol monophosphatase 1 0.0019 0.0012 0.0011
Loa Loa (eye worm) acetylcholine receptor protein 0.0075 0.0351 0.0416
Echinococcus multilocularis thyroid hormone receptor alpha 0.0102 0.0522 0.0519
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Echinococcus granulosus neuropeptide FF receptor 2 0.0083 0.0404 0.048
Loa Loa (eye worm) oxidoreductase 0.0025 0.0047 0.0051
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Echinococcus granulosus somatostatin receptor 0.0083 0.0404 0.048
Schistosoma mansoni aryl hydrocarbon receptor 0.003 0.0077 0.0176
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Schistosoma mansoni pol-related 0.0025 0.0047 0.0101
Loa Loa (eye worm) hypothetical protein 0.0121 0.0636 0.0757
Brugia malayi acetyltransferase, GNAT family protein 0.0083 0.0404 0.0478
Trichomonas vaginalis aldo-keto reductase, putative 0.0025 0.0047 0.044
Loa Loa (eye worm) hypothetical protein 0.0168 0.0919 0.1096
Schistosoma mansoni hypothetical protein 0.0185 0.1023 0.2509
Echinococcus granulosus Nuclear hormone receptor HR96 0.0018 0.0005 0.0003
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0075 0.0351 0.0414
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0093 0.0464 0.0549
Entamoeba histolytica acyl-coA synthetase, putative 0.0026 0.0058 0.101
Echinococcus granulosus g-protein coupled receptor 0.0083 0.0404 0.048
Echinococcus granulosus thyroid hormone receptor alpha 0.0018 0.0005 0.0003
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0083 0.0404 0.048
Echinococcus granulosus alpha 1A adrenergic receptor 0.0083 0.0404 0.048
Schistosoma mansoni hypothetical protein 0.0038 0.0128 0.0302
Echinococcus granulosus histone acetyltransferase KAT2B 0.0081 0.039 0.0463
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0024 0.0046 0.1645
Loa Loa (eye worm) hypothetical protein 0.002 0.0019 0.0018
Trichomonas vaginalis CMGC family protein kinase 0.0031 0.0085 0.0931
Brugia malayi Cation transporter family protein 0.0168 0.0919 0.1094
Schistosoma mansoni hypothetical protein 0.0065 0.0291 0.0703
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0038 0.0128 0.0146
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0038 0.0128 0.0148
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0304 0.1753 0.2096
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0404 0.0401
Echinococcus granulosus rhodopsin orphan GPCR 0.0083 0.0404 0.048
Mycobacterium ulcerans hypothetical protein 0.0026 0.0058 1
Echinococcus multilocularis lamin dm0 0.0043 0.0159 0.0156
Echinococcus multilocularis microtubule associated protein 2 0.0683 0.4061 0.406
Entamoeba histolytica aldose reductase, putative 0.0025 0.0047 0.0764
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0025 0.0047 0.0103
Echinococcus granulosus lamin dm0 0.0043 0.0159 0.0187
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0038 0.0128 0.0146
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0019 0.0012 0.0002
Echinococcus multilocularis neuropeptide Y receptor 0.0083 0.0404 0.0401
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0168 0.0919 0.1097
Echinococcus granulosus Protein patched homolog 1 0.0023 0.0036 0.0039
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0168 0.0919 0.1096
Loa Loa (eye worm) hypothetical protein 0.0075 0.0351 0.0416
Trichomonas vaginalis aldo/keto reductase, putative 0.0025 0.0047 0.044
Schistosoma mansoni amine GPCR 0.0083 0.0404 0.0982
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0091 0.0087
Loa Loa (eye worm) hypothetical protein 0.0093 0.0464 0.0551
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Onchocerca volvulus 0.0025 0.0047 0.0049
Onchocerca volvulus Deterin homolog 0.1386 0.8352 1
Entamoeba histolytica hypothetical protein 0.0038 0.0128 0.2559
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0018 0.0005 0.0002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0083 0.0404 0.0401
Echinococcus multilocularis G protein coupled receptor 139 0.0127 0.0674 0.0671
Brugia malayi hypothetical protein 0.0083 0.0404 0.0477
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0083 0.0404 0.048
Echinococcus multilocularis aldo keto reductase family 1, member B4 0.0025 0.0047 0.0044
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0083 0.0404 0.0401
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0038 0.0128 0.0146
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.038 0.2216 0.2648
Onchocerca volvulus 0.0075 0.0351 0.0414
Echinococcus granulosus 7TM GPCR rhodopsin 0.0083 0.0404 0.048
Echinococcus granulosus glycine receptor subunit beta 0.0168 0.0919 0.1097
Loa Loa (eye worm) hypothetical protein 0.0083 0.0404 0.0479
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.002 0.002 0.0017
Echinococcus granulosus aldo keto reductase family 1 member B4 0.0025 0.0047 0.0052

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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