Detailed information for compound 787186

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 489.998 | Formula: C21H20ClN5O3S2
  • H donors: 0 H acceptors: 3 LogP: 4.48 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCS(=O)(=O)c1nn2c(=NC(=O)/C(=C/c3cc(n(c3C)c3ccc(c(c3)Cl)C)C)/C2=N)s1
  • InChi: 1S/C21H20ClN5O3S2/c1-5-32(29,30)21-25-27-18(23)16(19(28)24-20(27)31-21)9-14-8-12(3)26(13(14)4)15-7-6-11(2)17(22)10-15/h6-10,23H,5H2,1-4H3/b16-9+,23-18?
  • InChiKey: ABPCYJOMACOXPA-NWECJKKASA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major glucose transporter/membrane transporter D2, putative 0.0037 0.0644 0.868
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0644 0.274
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0124 0.0345
Loa Loa (eye worm) hypothetical protein 0.0029 0.0486 0.143
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0947 0.1019
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0726 0.3102
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Plasmodium falciparum calcium-dependent protein kinase 1 0.0036 0.0635 0.0597
Trypanosoma cruzi DNA polymerase eta, putative 0.0007 0.0043 0.0253
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0069 0.1292 0.1403
Schistosoma mansoni hypothetical protein 0.0018 0.0265 0.0288
Onchocerca volvulus 0.0017 0.0241 0.0694
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0026 0.0437 0.1826
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0124 0.0345
Loa Loa (eye worm) hypothetical protein 0.0006 0.0021 0.0037
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0006 0.002 0.0012
Leishmania major DNA damage repair protein, putative 0.0007 0.0043 0.0253
Leishmania major DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0345
Trichomonas vaginalis glucose transporter, putative 0.0037 0.0644 0.274
Trypanosoma brucei unspecified product 0.0022 0.0345 0.4498
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0022 0.0345 0.1008
Onchocerca volvulus 0.0017 0.0241 0.0694
Leishmania major lysyl-tRNA synthetase, putative 0.0026 0.0437 0.5783
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0022 0.0345 0.142
Brugia malayi glycyl-tRNA synthetase 0.0007 0.004 0.0093
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0345
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0043 0.0253
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0345
Toxoplasma gondii sugar transporter ST1 0.0017 0.0241 0.0327
Trypanosoma cruzi hexose transporter, putative 0.002 0.0309 0.3994
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0124 0.0345
Schistosoma mansoni cpg binding protein 0.0034 0.0597 0.0648
Mycobacterium tuberculosis Conserved protein 0.0041 0.0726 0.137
Leishmania major DNA polymerase eta, putative 0.0007 0.0043 0.0253
Plasmodium falciparum calcium-dependent protein kinase 5 0.0036 0.0635 0.0597
Trichomonas vaginalis bromodomain-containing protein, putative 0.0046 0.0825 0.3543
Trichomonas vaginalis sugar transporter, putative 0.0037 0.0644 0.274
Trypanosoma brucei glucose transporter, putative 0.0037 0.0644 0.868
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0437 0.5885
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0634 0.0679
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0124 0.0345
Onchocerca volvulus 0.0017 0.0241 0.0694
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0738 1
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0007 0.004 0.0093
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0043 0.0253
Trichomonas vaginalis helicase, putative 0.0007 0.0054 0.0132
Loa Loa (eye worm) hypothetical protein 0.0041 0.0726 0.2148
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0069 0.0065
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0345 0.4498
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.1221 0.1813
Echinococcus multilocularis solute carrier family 22 0.0017 0.0241 0.0252
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0017 0.0241 0.0201
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0124 0.0345
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0054 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0241 0.0956
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0124 0.0125
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0124 0.0135
Brugia malayi Nuclear hormone receptor-like 1 0.0006 0.0021 0.0037
Schistosoma mansoni sugar transporter 0.0017 0.0241 0.0261
Schistosoma mansoni zinc finger protein 0.0006 0.002 0.0022
Trypanosoma brucei unspecified product 0.0015 0.0209 0.2588
Trypanosoma brucei glucose transporter 1E 0.0037 0.0644 0.868
Schistosoma mansoni hypothetical protein 0.0039 0.0682 0.074
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Treponema pallidum prolyl-tRNA synthetase 0.0013 0.0158 1
Toxoplasma gondii glycyl-tRNA synthetase 0.0007 0.004 0.0024
Echinococcus granulosus solute carrier family 22 0.0017 0.0241 0.0252
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0726 0.3102
Trypanosoma brucei THT1 - hexose transporter, putative 0.0037 0.0644 0.868
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0124 0.0135
Mycobacterium tuberculosis Conserved protein 0.0041 0.0726 0.137
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0644 0.868
Trypanosoma brucei DNA polymerase kappa, putative 0.0007 0.0043 0.0253
Brugia malayi Sugar transporter family protein 0.0017 0.0241 0.0694
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Brugia malayi PHD-finger family protein 0.0006 0.002 0.0033
Mycobacterium tuberculosis Probable lipase LipE 0.0041 0.0726 0.137
Brugia malayi Sugar transporter family protein 0.0017 0.0241 0.0694
Trypanosoma brucei glucose transporter, putative 0.0037 0.0644 0.868
Onchocerca volvulus 0.0172 0.3345 1
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0017 0.0241 0.303
Echinococcus granulosus dna polymerase kappa 0.0022 0.0345 0.0365
Echinococcus granulosus solute carrier family 22 0.0017 0.0241 0.0252
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Onchocerca volvulus 0.0041 0.0726 0.2148
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0046 0.0825 0.1213
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Schistosoma mansoni sugar transporter 0.0017 0.0241 0.0261
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Trypanosoma brucei DNA damage repair protein, putative 0.0007 0.0043 0.0253
Schistosoma mansoni hypothetical protein 0.0192 0.3762 0.4083
Echinococcus multilocularis beta LACTamase domain containing family member 0.0041 0.0726 0.0778
Mycobacterium tuberculosis Probable esterase LipL 0.0041 0.0726 0.137
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0006 0.002 0.0012
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0007 0.0043 0.0027
Trypanosoma brucei glucose transporter 2A 0.0037 0.0644 0.868
Schistosoma mansoni hypothetical protein 0.0018 0.0265 0.0288
Trichomonas vaginalis glucose transporter, putative 0.0017 0.0241 0.0956
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0124 0.0345
Brugia malayi acetyltransferase, GNAT family protein 0.0156 0.3031 0.906
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0192 0.3749 0.5643
Echinococcus granulosus General substrate transporter 0.0102 0.195 0.2109
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0749 1
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0017 0.0241 0.0252
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0209 0.2588
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0124 0.0345
Schistosoma mansoni cpg binding protein 0.0034 0.0597 0.0648
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0192 0.3749 0.3724
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0007 0.004 0.0069
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0241 0.0956
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Trypanosoma cruzi hexose transporter, putative 0.0017 0.0241 0.303
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0345 0.4578
Toxoplasma gondii lysine-tRNA ligase 0.0026 0.0437 0.0625
Onchocerca volvulus 0.0017 0.0241 0.0694
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0119 0.2284 0.2472
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0124 0.0345
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0345
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0634 0.0679
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0345 0.1008
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0124 0.0125
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0036 0.0634 0.1875
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0124 0.0345
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Echinococcus granulosus lysyl tRNA synthetase 0.0026 0.0437 0.0465
Schistosoma mansoni hypothetical protein 0.0018 0.0265 0.0288
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0041 0.0738 0.1081
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Brugia malayi hypothetical protein 0.0017 0.0241 0.0694
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0009 0.001
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Onchocerca volvulus 0.0017 0.0241 0.0694
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0007 0.004 0.0034
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0041 0.0726 0.137
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0726 0.0787
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0738 1
Schistosoma mansoni nuclear receptor nhr-48 0.0005 0.0009 0.001
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0265 0.0278
Loa Loa (eye worm) hypothetical protein 0.0036 0.062 0.1831
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0241 0.0956
Leishmania major DNA polymerase eta, putative 0.0022 0.0345 0.4498
Echinococcus granulosus beta LACTamase domain containing family member 0.0041 0.0726 0.0778
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Echinococcus granulosus histone acetyltransferase KAT2B 0.0152 0.2944 0.3188
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0265 0.0768
Loa Loa (eye worm) acetyltransferase 0.0156 0.3031 0.906
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0017 0.0241 0.0261
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Plasmodium vivax sugar transporter, putative 0.0017 0.0241 0.0201
Mycobacterium tuberculosis Probable hydrolase 0.0041 0.0726 0.137
Mycobacterium tuberculosis Conserved protein 0.0041 0.0726 0.137
Leishmania major threonyl-tRNA synthetase, putative 0.0007 0.004 0.0218
Onchocerca volvulus 0.0017 0.0241 0.0694
Schistosoma mansoni nuclear receptor 0.0005 0.0009 0.001
Brugia malayi hypothetical protein 0.0172 0.3345 1
Schistosoma mansoni protein kinase 0.0036 0.0634 0.0689
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0108 0.0108
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0054 0.0132
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0041 0.0726 0.2148
Onchocerca volvulus 0.0017 0.0241 0.0694
Loa Loa (eye worm) hypothetical protein 0.0018 0.0265 0.0768
Leishmania major glucose transporter, lmgt1 0.0037 0.0644 0.868
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0124 0.0345
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0124 0.0135
Plasmodium vivax lysine--tRNA ligase, putative 0.0026 0.0437 0.0399
Onchocerca volvulus 0.0017 0.0241 0.0694
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0023 0.0372 0.1536
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0124 0.0345
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0036 0.062 0.2634
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0241 0.0956
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0006 0.0021 0.0023
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0644 0.274
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0124 0.0345
Onchocerca volvulus 0.0017 0.0241 0.0694
Trichomonas vaginalis DNA polymerase eta, putative 0.0022 0.0345 0.142
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0124 0.0125
Schistosoma mansoni DNA polymerase eta 0.0022 0.0345 0.0375
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Schistosoma mansoni bromodomain containing protein 0.0006 0.002 0.0022
Schistosoma mansoni glucose transport protein 0.0119 0.2284 0.2479
Echinococcus granulosus calcium dependent protein kinase 0.0034 0.0589 0.0631
Plasmodium falciparum mitogen-activated protein kinase 2 0.0192 0.3749 0.3724
Leishmania major hypothetical protein, conserved 0.0017 0.0241 0.303
Giardia lamblia DINP protein human, muc B family 0.0022 0.0345 0.4309
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0265 0.0278
Plasmodium vivax CDK-related protein kinase 6, putative 0.0504 1 1
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0124 0.0135
Schistosoma mansoni protein kinase 0.0036 0.0634 0.0689
Trypanosoma cruzi glucose transporter, putative 0.0017 0.0241 0.303
Loa Loa (eye worm) hypothetical protein 0.0041 0.0726 0.2148
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0006 0.0021 0.0037
Giardia lamblia Prolyl-tRNA synthetase 0.0036 0.062 0.818
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0124 0.0345
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0026 0.0437 0.5783
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0022 0.0357 0.065
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Leishmania major glucose transporter, lmgt2 0.0037 0.0644 0.868
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0124 0.0135
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Loa Loa (eye worm) hypothetical protein 0.0057 0.1041 0.3093
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0036 0.0634 0.1875
Plasmodium falciparum calcium-dependent protein kinase 4 0.0036 0.0635 0.0597
Trypanosoma cruzi hexose transporter 0.0037 0.0644 0.868
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0634 0.0679
Echinococcus granulosus Sugar transporter ERD6 protein 0.0017 0.0241 0.0252
Brugia malayi Nuclear hormone receptor-like 1 0.0006 0.0021 0.0037
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0006 0.0021 0.0023
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0345
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0209 0.2588
Mycobacterium ulcerans DNA polymerase IV 0.0022 0.0345 0.4578
Entamoeba histolytica protein kinase, putative 0.0036 0.0634 0.8388
Plasmodium falciparum calcium-dependent protein kinase 3 0.0036 0.0635 0.0597
Onchocerca volvulus Putative transporter 0.0017 0.0241 0.0694
Echinococcus multilocularis lysyl tRNA synthetase 0.0026 0.0437 0.0465
Loa Loa (eye worm) hypothetical protein 0.0006 0.002 0.0033
Mycobacterium leprae conserved hypothetical protein 0.0041 0.0726 1
Trichomonas vaginalis sugar transport protein, putative 0.0017 0.0241 0.0956
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0007 0.004 0.0093
Trichomonas vaginalis CAMK family protein kinase 0.0036 0.0634 0.2699
Chlamydia trachomatis lysine--tRNA ligase 0.0026 0.0437 1
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0726 0.9826
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Toxoplasma gondii ABC1 family protein 0.0041 0.0726 0.1062
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0124 0.0125
Schistosoma mansoni sugar transporter 0.0017 0.0241 0.0261
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0006 0.0021 0.0013
Brugia malayi polk-prov protein 0.0007 0.0043 0.01
Loa Loa (eye worm) hypothetical protein 0.0006 0.002 0.0033
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0124 0.0125
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0726 0.0688
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0007 0.0043 0.0027
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0069 0.0065
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0345
Trichomonas vaginalis sugar transporter, putative 0.0037 0.0644 0.274
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0124 0.0345
Echinococcus multilocularis geminin 0.0192 0.3762 0.4077
Plasmodium vivax calcium-dependent protein kinase, putative 0.0036 0.0635 0.0597
Loa Loa (eye worm) hypothetical protein 0.0006 0.0021 0.0037
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0036 0.062 0.1831
Leishmania major hypothetical protein, conserved 0.0041 0.0726 0.9826
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Toxoplasma gondii protein kinase, putative 0.0335 0.6626 1
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0017 0.0241 0.0423
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0043 0.0253
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Schistosoma mansoni glucose transporter 0.0017 0.0241 0.0261
Brugia malayi CXXC zinc finger family protein 0.0033 0.056 0.1651
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0007 0.0043 0.0027
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Brugia malayi hypothetical protein 0.0017 0.0241 0.0694
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0241 0.0694
Echinococcus granulosus synaptic vesicle 2 protein 0.0017 0.0241 0.0252
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.056 0.1651
Loa Loa (eye worm) major facilitator superfamily transporter 0.0017 0.0241 0.0694
Trypanosoma brucei glucose transporter, putative 0.0037 0.0644 0.868
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0119 0.2284 0.2472
Echinococcus multilocularis dna polymerase eta 0.0022 0.0345 0.0365
Trypanosoma brucei chrX additional, unordered contigs 0.0007 0.0043 0.0253
Onchocerca volvulus 0.0017 0.0241 0.0694
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0036 0.0634 0.0679
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0013 0.0158 0.1908
Brugia malayi hypothetical protein 0.0017 0.0241 0.0694
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0634 0.0679
Trichomonas vaginalis conserved hypothetical protein 0.0119 0.2284 1
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0007 0.004 0.0222
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0046 0.0825 0.1213
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0124 0.0135
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0738 1
Giardia lamblia Hexose transporter 0.0017 0.0241 0.2831
Loa Loa (eye worm) hypothetical protein 0.0041 0.0726 0.2148
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0124 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0124 0.0345
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0265 0.0278
Onchocerca volvulus 0.0017 0.0241 0.0694
Brugia malayi hypothetical protein 0.0006 0.0021 0.0037
Giardia lamblia DNA damage repair protein 0.0007 0.0043 0.0035
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Trypanosoma brucei hypothetical protein, conserved 0.0007 0.0043 0.0253
Giardia lamblia Lysyl-tRNA synthetase 0.0026 0.0437 0.5603
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0947 0.1028
Echinococcus granulosus dnaJ subfamily B 0.0464 0.9214 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0124 0.0125
Schistosoma mansoni protein kinase 0.0036 0.0634 0.0689
Mycobacterium ulcerans beta-lactamase 0.0041 0.0726 1
Echinococcus granulosus solute carrier family 22 0.0017 0.0241 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0007 0.004 0.0218
Trypanosoma brucei glucose transporter, putative 0.0037 0.0644 0.868
Loa Loa (eye worm) hypothetical protein 0.0006 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0437 0.1283
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0041 0.0726 0.0787
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0345 0.4498
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0036 0.062 0.0663
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0036 0.0634 0.1875
Onchocerca volvulus 0.0011 0.0124 0.0345
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0947 0.1019
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0119 0.2284 0.2472
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0124 0.0125
Schistosoma mansoni terminal deoxycytidyl transferase 0.0022 0.0345 0.0375
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0036 0.062 0.0673
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0052 0.0947 0.2812
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0124 0.0345
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0947 0.1028
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0124 0.0125
Loa Loa (eye worm) hypothetical protein 0.0022 0.0345 0.1008
Entamoeba histolytica protein kinase, putative 0.0036 0.0634 0.8388
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0007 0.004 0.0218
Leishmania major DNA polymerase kappa, putative 0.0007 0.0043 0.0253
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0682 0.2017
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0069 0.0065
Trypanosoma brucei glucose transporter, putative 0.0037 0.0644 0.868
Brugia malayi ecdysteroid receptor 0.0011 0.0124 0.0345
Onchocerca volvulus 0.0017 0.0241 0.0694
Brugia malayi Sugar transporter family protein 0.0119 0.2284 0.6821
Brugia malayi Bromodomain containing protein 0.0006 0.002 0.0033
Trypanosoma cruzi DNA polymerase eta, putative 0.0022 0.0345 0.4498
Brugia malayi Cam kinase protein 1 0.0036 0.0634 0.1875
Echinococcus multilocularis General substrate transporter 0.0102 0.195 0.2109
Trypanosoma brucei DNA polymerase eta, putative 0.0022 0.0345 0.4498
Echinococcus multilocularis solute carrier family 22 0.0017 0.0241 0.0252
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0041 0.0726 0.2148
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0041 0.0738 1
Echinococcus granulosus cpg binding protein 0.0034 0.0597 0.0639
Schistosoma mansoni coup transcription factor 0.0011 0.0124 0.0135
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0124 0.0345
Trypanosoma cruzi sugar transporter, putative 0.0017 0.0241 0.303
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Loa Loa (eye worm) hypothetical protein 0.0172 0.3345 1
Brugia malayi nuclear hormone receptor 0.0011 0.0124 0.0345
Loa Loa (eye worm) hypothetical protein 0.0041 0.0726 0.2148
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0036 0.0635 0.0597
Loa Loa (eye worm) hypothetical protein 0.0006 0.0021 0.0037
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0036 0.062 0.818
Trypanosoma brucei DNA polymerase IV, putative 0.0022 0.0345 0.4498
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0644 0.868
Loa Loa (eye worm) major facilitator superfamily transporter 0.0017 0.0241 0.0694
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0749 0.0712
Echinococcus granulosus dna polymerase eta 0.0022 0.0345 0.0365
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0022 0.0345 0.0627
Onchocerca volvulus 0.0041 0.0726 0.2148
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0036 0.0635 0.0925
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0026 0.0437 0.5783
Echinococcus granulosus glycyl tRNA synthetase 0.0007 0.004 0.0034
Echinococcus granulosus zinc finger protein 0.0006 0.002 0.0012
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0106 0.029
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0006 0.0021 0.0013
Brugia malayi major facilitator superfamily protein 0.0017 0.0241 0.0694
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0007 0.004 0.0218
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0437 0.0474
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Trypanosoma brucei DNA polymerase kappa, putative 0.0015 0.0209 0.2588
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0005 0.0009 0.001
Onchocerca volvulus 0.0017 0.0241 0.0694
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0124 0.0125
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0017 0.0241 0.0423
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0345
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0726 0.3102
Echinococcus multilocularis GPCR, family 2 0.0018 0.0265 0.0278
Trypanosoma cruzi DNA damage repair protein, putative 0.0007 0.0043 0.0253
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0635 0.0597
Trypanosoma cruzi DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Mycobacterium ulcerans hypothetical protein 0.0041 0.0726 1
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0036 0.0635 0.0925
Trichomonas vaginalis glucose transporter, putative 0.0037 0.0644 0.274
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0124 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0124 0.0345
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0015 0.0199 0.057
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0069 0.0074
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0036 0.062 0.0673
Chlamydia trachomatis proline--tRNA ligase 0.0013 0.0158 0.2978
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0007 0.004 0.0222
Leishmania major myo-inositol/proton symporter (MIT) 0.0017 0.0241 0.303
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0124 0.0345
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0041 0.0726 1
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0357 0.065
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0036 0.0635 0.0597
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0043 0.0253
Entamoeba histolytica hypothetical protein 0.0026 0.0437 0.5603
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0108 0.0108
Brugia malayi beta-lactamase 0.0041 0.0726 0.2148
Plasmodium falciparum hexose transporter 0.0119 0.2284 0.2253
Leishmania major protein kinase, putative 0.0036 0.0634 0.855
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0022 0.0345 0.4498
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0022 0.0357 0.4744
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0124 0.0345
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0057 0.1041 0.3093
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0052 0.0947 0.1019
Brugia malayi Calcitonin receptor-like protein seb-1 0.0057 0.1041 0.3093
Schistosoma mansoni hypothetical protein 0.0464 0.9214 1
Echinococcus granulosus geminin 0.0192 0.3762 0.4077
Mycobacterium ulcerans integral membrane transport protein 0.0017 0.0241 0.3083
Echinococcus multilocularis cpg binding protein 0.0034 0.0597 0.0639
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0041 0.0726 0.137
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0124 0.0345
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0749 1
Brugia malayi nuclear receptor RXR 0.0006 0.0021 0.0037
Trypanosoma brucei THT1 - hexose transporter, putative 0.0037 0.0644 0.868
Echinococcus multilocularis solute carrier family 22 0.0017 0.0241 0.0252
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0124 0.0135
Plasmodium falciparum DNA repair protein REV1, putative 0.0007 0.0043 0.0003
Mycobacterium tuberculosis Conserved hypothetical protein 0.0022 0.0345 0.0627
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Leishmania major glucose transporter, lmgt3 0.0037 0.0644 0.868
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0124 0.0135
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0119 0.2284 0.2472
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Mycobacterium ulcerans lipase LipD 0.0041 0.0726 1
Mycobacterium ulcerans hypothetical protein 0.0007 0.0043 0.0258
Schistosoma mansoni glucose transport protein 0.0119 0.2284 0.2479
Loa Loa (eye worm) beta-lactamase 0.0041 0.0726 0.2148
Echinococcus multilocularis synaptic vesicle 2 protein 0.0017 0.0241 0.0252
Trichomonas vaginalis esterase, putative 0.0041 0.0726 0.3102
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0007 0.004 0.0024
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0041 0.0738 1
Echinococcus granulosus solute carrier family 22 0.0017 0.0241 0.0252
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0124 0.0135
Schistosoma mansoni hypothetical protein 0.0119 0.2284 0.2479
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0046 0.0825 0.3543
Brugia malayi hypothetical protein 0.0006 0.0021 0.0037
Mycobacterium leprae Probable lipase LipE 0.0041 0.0726 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0124 0.0345
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Loa Loa (eye worm) histone methyltransferase 0.001 0.0108 0.0298
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0124 0.0125
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0057 0.1041 0.3093
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0261 0.5141 1
Trypanosoma cruzi hypothetical protein, conserved 0.0041 0.0726 0.9826
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0036 0.062 0.1831
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0052 0.0947 0.2812
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0007 0.004 0.0093
Schistosoma mansoni nuclear hormone receptor 0.0005 0.0009 0.001
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Echinococcus multilocularis solute carrier family 22 0.0017 0.0241 0.0252
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0634 0.0679
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0022 0.0345 0.0365
Loa Loa (eye worm) sugar transporter 0.0017 0.0241 0.0694
Echinococcus multilocularis glycyl tRNA synthetase 0.0007 0.004 0.0034
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Onchocerca volvulus 0.0017 0.0241 0.0694
Schistosoma mansoni serine/threonine protein kinase 0.0036 0.0634 0.0689
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Brugia malayi major facilitator superfamily protein 0.0017 0.0241 0.0694
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Loa Loa (eye worm) hypothetical protein 0.0007 0.004 0.0093
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0046 0.0825 0.0788
Loa Loa (eye worm) hypothetical protein 0.0041 0.0726 0.2148
Schistosoma mansoni zinc finger protein 0.0005 0.0009 0.001
Onchocerca volvulus 0.0041 0.0726 0.2148
Plasmodium falciparum protein kinase 7 0.0335 0.6626 0.6612
Brugia malayi lysyl-tRNA synthetase 0.0026 0.0437 0.1283
Trichomonas vaginalis conserved hypothetical protein 0.0007 0.0054 0.0132
Onchocerca volvulus 0.0017 0.0241 0.0694
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0124 0.0125
Trypanosoma brucei sugar transporter, putative 0.0017 0.0241 0.303
Mycobacterium ulcerans sugar transporter 0.0017 0.0241 0.3083
Trichomonas vaginalis conserved hypothetical protein 0.0017 0.0241 0.0956
Echinococcus multilocularis calcium dependent protein kinase 0.0034 0.0589 0.0631
Loa Loa (eye worm) hypothetical protein 0.0036 0.062 0.1831
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0005 0.0009 0.001
Toxoplasma gondii transporter, major facilitator family protein 0.0017 0.0241 0.0327
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0124 0.0345
Schistosoma mansoni glycyl-tRNA synthetase 0.0007 0.004 0.0043
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0054 0.0132
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0124 0.0125
Plasmodium falciparum proline--tRNA ligase 0.0041 0.0738 0.0701
Schistosoma mansoni hypothetical protein 0.0192 0.3762 0.4083
Toxoplasma gondii sugar transporter ST3 0.0017 0.0241 0.0327
Brugia malayi ImpB/MucB/SamB family protein 0.0022 0.0345 0.1008
Onchocerca volvulus 0.0033 0.056 0.1651
Brugia malayi nuclear receptor NHR-88 0.0011 0.0124 0.0345
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0052 0.0947 0.1019
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0241 0.0694
Trypanosoma brucei DNA polymerase kappa, putative 0.0022 0.0345 0.4498
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0124 0.0135
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0026 0.0437 0.5885
Schistosoma mansoni cpg binding protein 0.0033 0.056 0.0608
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0119 0.2284 0.2472
Trypanosoma cruzi DNA damage repair protein, putative 0.0007 0.0043 0.0253
Trypanosoma brucei unspecified product 0.0015 0.0209 0.2588
Trypanosoma brucei glucose transporter, putative 0.0037 0.0644 0.868
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0124 0.0345
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0054 0.0132
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0036 0.0634 0.0679
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Trichomonas vaginalis myo-inositol transporter, putative 0.0017 0.0241 0.0956
Brugia malayi Major Facilitator Superfamily protein 0.0017 0.0241 0.0694
Trypanosoma brucei hypothetical protein, conserved 0.0041 0.0726 0.9826
Brugia malayi beta-lactamase family protein 0.0041 0.0726 0.2148
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Trichomonas vaginalis D-aminoacylase, putative 0.0041 0.0726 0.3102
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0036 0.0634 0.855
Schistosoma mansoni sugar transporter 0.0017 0.0241 0.0261
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0124 0.0125
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0052 0.0947 0.1028
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0007 0.004 0.003
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0265 0.0768
Echinococcus granulosus histone acetyltransferase KAT2B 0.0046 0.0825 0.0887
Trypanosoma brucei glucose transporter, putative 0.0037 0.0644 0.868
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0119 0.2284 0.2472
Entamoeba histolytica deoxycytidyl transferase, putative 0.0022 0.0345 0.4309
Loa Loa (eye worm) hypothetical protein 0.0041 0.0726 0.2148
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0124 0.0345
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0036 0.0635 0.0925
Mycobacterium tuberculosis Probable lipase LipD 0.0041 0.0726 0.137
Echinococcus granulosus GPCR family 2 0.0018 0.0265 0.0278
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0119 0.2284 0.2472
Schistosoma mansoni bromodomain containing protein 0.0006 0.002 0.0022
Plasmodium vivax proline--tRNA ligase, putative 0.0041 0.0738 0.0701
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0041 0.0726 0.137
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0054 0.0132
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0124 0.0125
Loa Loa (eye worm) hypothetical protein 0.0006 0.0021 0.0037
Loa Loa (eye worm) hypothetical protein 0.0011 0.0124 0.0345
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0007 0.0054 0.0132
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0022 0.0345 0.0375
Plasmodium falciparum calcium-dependent protein kinase 2 0.0036 0.0635 0.0597
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0124 0.0345
Trypanosoma cruzi hypothetical protein, conserved 0.0007 0.0043 0.0253
Onchocerca volvulus 0.0017 0.0241 0.0694
Echinococcus multilocularis dnaJ subfamily B 0.0464 0.9214 1
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0036 0.062 0.0663
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0022 0.0345 0.0365
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0124 0.0135
Loa Loa (eye worm) hypothetical protein 0.0007 0.0043 0.01
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0054 0.0132
Plasmodium vivax hexose transporter 0.0119 0.2284 0.2253
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0124 0.0125
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0007 0.004 0.0093
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0036 0.062 0.849
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0119 0.2284 0.2472
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0007 0.004 0.0222
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0069 0.0065
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Loa Loa (eye worm) hypothetical protein 0.0036 0.0634 0.1875
Echinococcus multilocularis dna polymerase kappa 0.0022 0.0345 0.0365
Brugia malayi beta-lactamase family protein 0.0041 0.0726 0.2148
Loa Loa (eye worm) sugar transporter 0.0119 0.2284 0.6821
Plasmodium falciparum lysine--tRNA ligase 0.0026 0.0437 0.0399
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0017 0.0241 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0156 0.3031 0.329
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0644 0.868
Giardia lamblia Sugar-proton symporter 0.0017 0.0241 0.2831
Loa Loa (eye worm) hypothetical protein 0.0039 0.0682 0.2017
Plasmodium vivax DNA repair protein REV1, putative 0.0007 0.0043 0.0003
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0036 0.0634 0.0679
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0124 0.0125
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0265 0.0278
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0007 0.004 0.0218
Toxoplasma gondii sugar transporter ST2 0.0017 0.0241 0.0327
Echinococcus multilocularis zinc finger protein 0.0006 0.002 0.0012
Trichomonas vaginalis penicillin-binding protein, putative 0.0041 0.0726 0.3102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0007 0.0054 0.0132
Schistosoma mansoni lysyl-tRNA synthetase 0.0026 0.0437 0.0474
Trypanosoma brucei THT1 - hexose transporter, putative 0.0037 0.0644 0.868
Echinococcus granulosus Threonyl tRNA synthetase C 0.0007 0.004 0.0034
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0265 0.0768
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0124 0.0135
Toxoplasma gondii facilitative glucose transporter GT1 0.0119 0.2284 0.3424
Loa Loa (eye worm) hypothetical protein 0.0017 0.0241 0.0694
Trichomonas vaginalis sugar transporter, putative 0.0037 0.0644 0.274
Trichomonas vaginalis sugar transporter, putative 0.0017 0.0241 0.0956
Brugia malayi steroid hormone receptor 0.0011 0.0124 0.0345
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0124 0.0345
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0026 0.0437 0.5885
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0017 0.0241 0.3083
Trypanosoma brucei glucose transporter, putative 0.0037 0.0644 0.868
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0156 0.3031 0.3283
Schistosoma mansoni hypothetical protein 0.0018 0.0265 0.0288
Mycobacterium ulcerans esterase/lipase LipP 0.0041 0.0726 1
Schistosoma mansoni glucose transport protein 0.0119 0.2284 0.2479
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0017 0.0241 0.3083
Schistosoma mansoni DNA polymerase IV / kappa 0.0007 0.0043 0.0046
Schistosoma mansoni nuclear receptor 0.0005 0.0009 0.001

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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