Detailed information for compound 827336

Basic information

Technical information
  • TDR Targets ID: 827336
  • Name: 3-[(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4- d][1,3]thiazol-2-yl)amino]-N-(3-ethoxypropyl) -4-methylbenzamide
  • MW: 411.539 | Formula: C18H25N3O4S2
  • H donors: 2 H acceptors: 3 LogP: 1.19 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOCCCNC(=O)c1ccc(c(c1)NC1=NC2C(S1)CS(=O)(=O)C2)C
  • InChi: 1S/C18H25N3O4S2/c1-3-25-8-4-7-19-17(22)13-6-5-12(2)14(9-13)20-18-21-15-10-27(23,24)11-16(15)26-18/h5-6,9,15-16H,3-4,7-8,10-11H2,1-2H3,(H,19,22)(H,20,21)
  • InChiKey: GATYQMORIPNRSY-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 3-[(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d]thiazol-2-yl)amino]-N-(3-ethoxypropyl)-4-methyl-benzamide
  • 3-[(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d]thiazol-2-yl)amino]-N-(3-ethoxypropyl)-4-methylbenzamide
  • 3-[(5,5-diketo-3a,4,6,6a-tetrahydrothieno[3,4-d]thiazol-2-yl)amino]-N-(3-ethoxypropyl)-4-methyl-benzamide
  • 3-[(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d][1,3]thiazol-2-yl)amino]-N-(3-ethoxypropyl)-4-methyl-benzamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0141 0.0193 0.0193
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0045 0.0013 0.0019
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0255 0.041 0.5
Schistosoma mansoni sodium/chloride dependent transporter 0.0141 0.0193 0.0193
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0021 0.0058
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1265 0.2322 0.7816
Echinococcus granulosus aurora kinase A 0.0608 0.1079 0.1536
Echinococcus multilocularis Serine:threonine protein kinase PLK4 0.3728 0.6986 1
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0141 0.0193 0.064
Echinococcus multilocularis roundabout 2 0.0049 0.0021 0.003
Brugia malayi cytochrome P450 0.0255 0.041 0.137
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0255 0.041 0.5
Loa Loa (eye worm) AUR protein kinase 0.0608 0.1079 0.3626
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0255 0.041 0.5
Trypanosoma brucei polo-like protein kinase 0.1607 0.297 1
Schistosoma mansoni nephrin 0.0049 0.0021 0.0021
Trypanosoma cruzi polo-like protein kinase, putative 0.1607 0.297 1
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0608 0.1079 1
Loa Loa (eye worm) hypothetical protein 0.0215 0.0335 0.1117
Echinococcus granulosus tyrosine protein kinase otk 0.0045 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0211 0.0328 0.1093
Schistosoma mansoni titin 0.0045 0.0013 0.0013
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0141 0.0193 0.0267
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0234 0.037 0.0519
Loa Loa (eye worm) hypothetical protein 0.0045 0.0013 0.0033
Trypanosoma cruzi cytochrome P450, putative 0.0415 0.0713 0.1185
Loa Loa (eye worm) TK protein kinase 0.0152 0.0215 0.0714
Onchocerca volvulus 0.0141 0.0193 0.0628
Echinococcus granulosus sodium and chloride dependent glycine 0.0141 0.0193 0.0267
Loa Loa (eye worm) hypothetical protein 0.0141 0.0193 0.064
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0211 0.0328 0.0469
Loa Loa (eye worm) hypothetical protein 0.0215 0.0335 0.1117
Trypanosoma brucei cytochrome P450, putative 0.0415 0.0713 0.1185
Echinococcus granulosus hemicentin 1 0.0045 0.0013 0.0008
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0141 0.0193 0.0277
Brugia malayi serine/threonine kinase 12 0.0608 0.1079 0.3626
Echinococcus multilocularis hemicentin 1 0.0045 0.0013 0.0019
Loa Loa (eye worm) hypothetical protein 0.016 0.0231 0.0767
Echinococcus granulosus neuroglian 0.0049 0.0021 0.0019
Echinococcus multilocularis sodium and chloride dependent glycine 0.0141 0.0193 0.0277
Loa Loa (eye worm) hypothetical protein 0.0211 0.0328 0.1093
Trypanosoma cruzi aurora B kinase, putative 0.0608 0.1079 0.2614
Loa Loa (eye worm) hypothetical protein 0.0234 0.037 0.1234
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0013 0.0033
Schistosoma mansoni cell adhesion molecule 0.0045 0.0013 0.0013
Brugia malayi serine/threonine-protein kinase plk-2 0.1607 0.297 1
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0255 0.041 0.5
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0013 0.0033
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0255 0.041 0.5
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0045 0.0013 0.0033
Brugia malayi serine/threonine protein kinase 6 0.0608 0.1079 0.3626
Loa Loa (eye worm) hypothetical protein 0.0828 0.1495 0.5027
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0049 0.0021 0.003
Loa Loa (eye worm) hypothetical protein 0.0046 0.0014 0.0035
Schistosoma mansoni nephrin 0.0239 0.0379 0.0379
Loa Loa (eye worm) cytochrome P450 family protein 0.0996 0.1814 0.6102
Onchocerca volvulus 0.101 0.1839 0.6183
Brugia malayi hypothetical protein 0.0215 0.0335 0.1117
Echinococcus multilocularis aurora kinase A 0.0608 0.1079 0.1545
Trichomonas vaginalis CAMK family protein kinase 0.1607 0.297 1
Echinococcus granulosus lachesin 0.0045 0.0013 0.0008
Loa Loa (eye worm) hypothetical protein 0.0141 0.0193 0.064
Schistosoma mansoni neuroglian 0.0049 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0255 0.041 0.041
Loa Loa (eye worm) AUR protein kinase 0.0608 0.1079 0.3626
Brugia malayi Cytochrome P450 family protein 0.0255 0.041 0.137
Schistosoma mansoni protein kinase 0.0608 0.1079 0.1079
Leishmania major protein kinase, putative 0.0608 0.1079 0.2614
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0141 0.0193 0.0267
Loa Loa (eye worm) CYP4Cod1 0.0415 0.0713 0.2393
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0049 0.0021 0.003
Schistosoma mansoni cell adhesion molecule 0.0049 0.0021 0.0021
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1607 0.297 0.4252
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0012 0.0029
Brugia malayi Fibronectin type III domain containing protein 0.0215 0.0335 0.1117
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0129 0.0171 0.0235
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0042 0.0007 0.0013
Leishmania major cytochrome p450-like protein 0.0415 0.0713 0.1185
Echinococcus granulosus sodium and chloride dependent glycine 0.0141 0.0193 0.0267
Loa Loa (eye worm) hypothetical protein 0.0212 0.0328 0.1094
Onchocerca volvulus Serine\/threonine kinase homolog 0.1607 0.297 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.1265 0.2322 0.7816
Echinococcus multilocularis 0.0255 0.041 0.0587
Schistosoma mansoni septate junction protein 0.0045 0.0013 0.0013
Entamoeba histolytica serine/threonine protein kinase, putative 0.1607 0.297 1
Echinococcus multilocularis tyrosine protein kinase otk 0.0045 0.0013 0.0019
Schistosoma mansoni sodium/chloride dependent transporter 0.0828 0.1495 0.1495
Schistosoma mansoni cell adhesion molecule 0.0237 0.0377 0.0377
Echinococcus multilocularis neuroglian 0.0049 0.0021 0.003
Echinococcus granulosus roundabout 2 0.0049 0.0021 0.0019
Trichomonas vaginalis CAMK family protein kinase 0.1607 0.297 1
Onchocerca volvulus Tyrosine kinase homolog 0.1055 0.1924 0.6468
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0045 0.0012 0.0007
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0007 0.0013
Schistosoma mansoni titin 0.0042 0.0007 0.0007
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0129 0.0171 0.0245
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0211 0.0328 0.0328
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0141 0.0193 0.0193
Brugia malayi hypothetical protein 0.0345 0.058 0.1945
Loa Loa (eye worm) AUR protein kinase 0.0608 0.1079 0.3626
Brugia malayi Immunoglobulin I-set domain containing protein 0.0152 0.0215 0.0714
Brugia malayi hypothetical protein 0.0141 0.0193 0.064
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0141 0.0193 0.0193
Loa Loa (eye worm) cytochrome P450 0.0255 0.041 0.137
Brugia malayi Immunoglobulin I-set domain containing protein 0.0215 0.0335 0.1117
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0255 0.041 0.5
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0255 0.041 0.5
Echinococcus multilocularis roundabout 2 0.0261 0.0421 0.0603
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1607 0.297 1
Echinococcus granulosus defective proboscis extension response 0.0211 0.0328 0.0459
Echinococcus granulosus Immunoglobulin 0.0211 0.0328 0.0459
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0064 0.0049 0.0155
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0007 0.0007
Mycobacterium leprae Conserved hypothetical protein 0.0255 0.041 0.5
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0045 0.0012 0.0017
Schistosoma mansoni tyrosine kinase 0.0129 0.0171 0.0171
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0141 0.0193 0.0277
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0141 0.0193 0.064
Echinococcus granulosus neuroglian 0.0235 0.0372 0.0522
Loa Loa (eye worm) hypothetical protein 0.0257 0.0414 0.1382
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0255 0.041 0.5
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0141 0.0193 0.0193
Trypanosoma cruzi polo-like protein kinase, putative 0.1607 0.297 1
Plasmodium falciparum serine/threonine protein kinase, putative 0.0608 0.1079 1
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0129 0.0171 0.0245
Onchocerca volvulus 0.0828 0.1495 0.5021
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0141 0.0193 0.064
Loa Loa (eye worm) hypothetical protein 0.0045 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0215 0.0335 0.1117
Loa Loa (eye worm) hypothetical protein 0.0141 0.0193 0.064
Trichomonas vaginalis CAMK family protein kinase 0.1607 0.297 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0141 0.0193 0.0193
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0255 0.041 0.5
Loa Loa (eye worm) hypothetical protein 0.0141 0.0193 0.064
Toxoplasma gondii cytochrome p450 superfamily protein 0.0255 0.041 0.2443
Schistosoma mansoni sodium-dependent amino acid transporter 0.0141 0.0193 0.0193
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0828 0.1495 0.5027
Echinococcus granulosus roundabout 2 0.0261 0.0421 0.0593
Loa Loa (eye worm) hypothetical protein 0.0045 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0045 0.0013 0.0033
Brugia malayi Peroxidasin 0.0046 0.0014 0.0035
Loa Loa (eye worm) cytochrome P450 family protein 0.0415 0.0713 0.2393
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0255 0.041 0.5
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0049 0.0021 0.003
Echinococcus multilocularis titin 0.0042 0.0007 0.0011
Echinococcus granulosus contactin 0.0049 0.0021 0.0019
Brugia malayi serine/threonine-protein kinase 6 0.0608 0.1079 0.3626
Schistosoma mansoni sodium/chloride dependent transporter 0.0156 0.0222 0.0222
Toxoplasma gondii aurora kinase 0.0608 0.1079 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0021 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.1607 0.297 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0013 0.0033
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0045 0.0013 0.002
Brugia malayi protein unc-22 0.0042 0.0007 0.0013
Loa Loa (eye worm) hypothetical protein 0.0257 0.0414 0.1382
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0255 0.041 0.5
Trichomonas vaginalis CAMK family protein kinase 0.1607 0.297 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0415 0.0713 0.2393
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0255 0.041 0.5
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0049 0.0021 0.003
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0415 0.0713 1
Loa Loa (eye worm) serotonin transporter b 0.0828 0.1495 0.5027
Echinococcus granulosus peroxidasin 0.0046 0.0014 0.0009
Echinococcus granulosus cytochrome P450 2K1 0.0255 0.041 0.0577
Loa Loa (eye worm) hypothetical protein 0.0828 0.1495 0.5027
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0255 0.041 0.5
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0255 0.041 0.5
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0828 0.1495 0.1495
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0211 0.0328 0.0328
Echinococcus multilocularis neuroglian 0.0235 0.0372 0.0532
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0255 0.041 0.5
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0608 0.1079 0.1536
Onchocerca volvulus 0.0141 0.0193 0.0628
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0141 0.0193 0.064
Giardia lamblia Kinase, PLK 0.1607 0.297 1
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0608 0.1079 0.1545
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0049 0.0021 0.0019
Echinococcus multilocularis roundabout 2 0.0049 0.0021 0.003
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0141 0.0193 0.0193
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0345 0.058 0.1945
Schistosoma mansoni cell adhesion molecule 0.0049 0.0021 0.0021
Brugia malayi Cytochrome P450 family protein 0.0415 0.0713 0.2393
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1607 0.297 1
Loa Loa (eye worm) hypothetical protein 0.0141 0.0193 0.064
Echinococcus multilocularis Immunoglobulin 0.0211 0.0328 0.0469
Brugia malayi Prion-like- 0.0045 0.0013 0.0033
Echinococcus multilocularis sodium and chloride dependent glycine 0.0141 0.0193 0.0277
Loa Loa (eye worm) hypothetical protein 0.0045 0.0013 0.0033
Echinococcus granulosus Serine:threonine protein kinase PLK4 0.3728 0.6986 1
Schistosoma mansoni tyrosine kinase 0.0067 0.0054 0.0054
Schistosoma mansoni roundabout 0.0045 0.0013 0.0013
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0013 0.0033
Echinococcus multilocularis serotonin transporter 0.0828 0.1495 0.214
Loa Loa (eye worm) hypothetical protein 0.0141 0.0193 0.064
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0255 0.041 0.5
Loa Loa (eye worm) norepinephrine transporter 0.0828 0.1495 0.5027
Schistosoma mansoni septate junction protein 0.0045 0.0013 0.0013
Loa Loa (eye worm) solute carrier family 6 member 4 0.0828 0.1495 0.5027
Mycobacterium leprae putative cytochrome p450 0.0255 0.041 0.5
Onchocerca volvulus 0.0141 0.0193 0.0628
Loa Loa (eye worm) CAMK protein kinase 0.0042 0.0007 0.0013
Echinococcus multilocularis peroxidasin 0.0046 0.0014 0.002
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0255 0.041 0.5
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0141 0.0193 0.0193
Echinococcus multilocularis hemicentin 1 0.0045 0.0013 0.0019
Treponema pallidum sodium- and chloride- dependent transporter 0.0828 0.1495 0.5
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0255 0.041 0.5
Schistosoma mansoni vesicular amine transporter 0.0211 0.0328 0.0328
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0141 0.0193 0.0267
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0141 0.0193 0.064
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0021 0.0058
Brugia malayi Immunoglobulin I-set domain containing protein 0.0049 0.0021 0.0058
Trichomonas vaginalis CAMK family protein kinase 0.1607 0.297 1
Brugia malayi Cytochrome P450 family protein 0.0996 0.1814 0.6102
Trypanosoma cruzi cytochrome P450, putative 0.0415 0.0713 0.1185
Echinococcus multilocularis lachesin 0.0045 0.0013 0.0019
Brugia malayi Cytochrome P450 family protein 0.0415 0.0713 0.2393
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0255 0.041 0.5
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0049 0.0021 0.0021
Schistosoma mansoni cytochrome P450 0.0255 0.041 0.041
Loa Loa (eye worm) hypothetical protein 0.0045 0.0013 0.0033
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0828 0.1495 0.5027
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0141 0.0193 0.0193
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0141 0.0193 0.0267
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0049 0.0021 0.0058
Brugia malayi Immunoglobulin I-set domain containing protein 0.0045 0.0013 0.0033
Schistosoma mansoni serine/threonine protein kinase 0.1607 0.297 0.297
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0141 0.0193 0.064
Trypanosoma brucei aurora B kinase 0.0608 0.1079 0.2614
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0141 0.0193 0.0277
Trichomonas vaginalis CAMK family protein kinase 0.1607 0.297 1
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1607 0.297 0.4246
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0255 0.041 0.5
Echinococcus granulosus fibroblast growth factor receptor 4 0.0129 0.0171 0.0235
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0045 0.0013 0.0013
Echinococcus granulosus twitchin 0.025 0.04 0.0563
Schistosoma mansoni serine/threonine protein kinase 0.0608 0.1079 0.1079
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0141 0.0193 0.5
Echinococcus granulosus roundabout 2 0.0049 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.0141 0.0193 0.064
Echinococcus multilocularis Immunoglobulin 0.0211 0.0328 0.0469
Echinococcus granulosus serotonin transporter 0.0828 0.1495 0.2132

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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