Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0045 | 0.0013 | 0.0033 |
Schistosoma mansoni | cell adhesion molecule | 0.0045 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.0328 | 0.1093 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0141 | 0.0193 | 0.0277 |
Trypanosoma cruzi | aurora B kinase, putative | 0.0608 | 0.1079 | 0.2614 |
Loa Loa (eye worm) | hypothetical protein | 0.0234 | 0.037 | 0.1234 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.0231 | 0.0767 |
Echinococcus multilocularis | hemicentin 1 | 0.0045 | 0.0013 | 0.0019 |
Echinococcus granulosus | neuroglian | 0.0049 | 0.0021 | 0.0019 |
Echinococcus granulosus | hemicentin 1 | 0.0045 | 0.0013 | 0.0008 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0141 | 0.0193 | 0.0277 |
Brugia malayi | serine/threonine kinase 12 | 0.0608 | 0.1079 | 0.3626 |
Schistosoma mansoni | neuroglian | 0.0049 | 0.0021 | 0.0021 |
Schistosoma mansoni | hypothetical protein | 0.0255 | 0.041 | 0.041 |
Loa Loa (eye worm) | AUR protein kinase | 0.0608 | 0.1079 | 0.3626 |
Brugia malayi | Cytochrome P450 family protein | 0.0255 | 0.041 | 0.137 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1607 | 0.297 | 1 |
Echinococcus granulosus | lachesin | 0.0045 | 0.0013 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0193 | 0.064 |
Onchocerca volvulus | 0.101 | 0.1839 | 0.6183 | |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0996 | 0.1814 | 0.6102 |
Echinococcus multilocularis | aurora kinase A | 0.0608 | 0.1079 | 0.1545 |
Brugia malayi | hypothetical protein | 0.0215 | 0.0335 | 0.1117 |
Schistosoma mansoni | nephrin | 0.0239 | 0.0379 | 0.0379 |
Loa Loa (eye worm) | hypothetical protein | 0.0828 | 0.1495 | 0.5027 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase F | 0.0049 | 0.0021 | 0.003 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.0014 | 0.0035 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0045 | 0.0013 | 0.0033 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0255 | 0.041 | 0.5 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0045 | 0.0013 | 0.0033 |
Brugia malayi | serine/threonine protein kinase 6 | 0.0608 | 0.1079 | 0.3626 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0255 | 0.041 | 0.5 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.1607 | 0.297 | 1 |
Schistosoma mansoni | nephrin | 0.0049 | 0.0021 | 0.0021 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.1607 | 0.297 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.0335 | 0.1117 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0608 | 0.1079 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0608 | 0.1079 | 0.3626 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0255 | 0.041 | 0.5 |
Trypanosoma brucei | polo-like protein kinase | 0.1607 | 0.297 | 1 |
Echinococcus multilocularis | roundabout 2 | 0.0049 | 0.0021 | 0.003 |
Brugia malayi | cytochrome P450 | 0.0255 | 0.041 | 0.137 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0255 | 0.041 | 0.5 |
Echinococcus multilocularis | Serine:threonine protein kinase PLK4 | 0.3728 | 0.6986 | 1 |
Echinococcus granulosus | aurora kinase A | 0.0608 | 0.1079 | 0.1536 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0141 | 0.0193 | 0.064 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0255 | 0.041 | 0.5 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0141 | 0.0193 | 0.0193 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0049 | 0.0021 | 0.0058 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.1265 | 0.2322 | 0.7816 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0141 | 0.0193 | 0.0193 |
Echinococcus multilocularis | neurotracting:lsamp:neurotrimin:obcam | 0.0045 | 0.0013 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.0335 | 0.1117 |
Trypanosoma brucei | cytochrome P450, putative | 0.0415 | 0.0713 | 0.1185 |
Echinococcus multilocularis | basement membrane specific heparan sulfate | 0.0211 | 0.0328 | 0.0469 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0141 | 0.0193 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0193 | 0.064 |
Onchocerca volvulus | 0.0141 | 0.0193 | 0.0628 | |
Trypanosoma cruzi | cytochrome P450, putative | 0.0415 | 0.0713 | 0.1185 |
Loa Loa (eye worm) | TK protein kinase | 0.0152 | 0.0215 | 0.0714 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0234 | 0.037 | 0.0519 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0013 | 0.0033 |
Echinococcus granulosus | tyrosine protein kinase otk | 0.0045 | 0.0013 | 0.0008 |
Loa Loa (eye worm) | hypothetical protein | 0.0211 | 0.0328 | 0.1093 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0141 | 0.0193 | 0.0267 |
Schistosoma mansoni | titin | 0.0045 | 0.0013 | 0.0013 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0152 | 0.0215 | 0.0714 |
Loa Loa (eye worm) | AUR protein kinase | 0.0608 | 0.1079 | 0.3626 |
Echinococcus multilocularis | fibroblast growth factor receptor 4 | 0.0129 | 0.0171 | 0.0245 |
Schistosoma mansoni | Neurotrimin precursor (hNT) | 0.0211 | 0.0328 | 0.0328 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0141 | 0.0193 | 0.0193 |
Brugia malayi | hypothetical protein | 0.0345 | 0.058 | 0.1945 |
Schistosoma mansoni | titin | 0.0042 | 0.0007 | 0.0007 |
Echinococcus granulosus | tyrosine protein kinase transmembrane receptor | 0.0045 | 0.0012 | 0.0007 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0042 | 0.0007 | 0.0013 |
Echinococcus granulosus | roundabout 2 | 0.0049 | 0.0021 | 0.0019 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1607 | 0.297 | 1 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.1055 | 0.1924 | 0.6468 |
Schistosoma mansoni | tyrosine kinase | 0.0129 | 0.0171 | 0.0171 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0141 | 0.0193 | 0.0277 |
Echinococcus multilocularis | tyrosine protein kinase transmembrane receptor | 0.0045 | 0.0012 | 0.0017 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0255 | 0.041 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0042 | 0.0007 | 0.0007 |
Echinococcus granulosus | Immunoglobulin | 0.0211 | 0.0328 | 0.0459 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0064 | 0.0049 | 0.0155 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.1607 | 0.297 | 1 |
Echinococcus granulosus | defective proboscis extension response | 0.0211 | 0.0328 | 0.0459 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0255 | 0.041 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0215 | 0.0335 | 0.1117 |
Echinococcus multilocularis | roundabout 2 | 0.0261 | 0.0421 | 0.0603 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0255 | 0.041 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 | 0.0255 | 0.041 | 0.137 |
Brugia malayi | hypothetical protein | 0.0141 | 0.0193 | 0.064 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0141 | 0.0193 | 0.0193 |
Brugia malayi | Fibronectin type III domain containing protein | 0.0215 | 0.0335 | 0.1117 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0045 | 0.0012 | 0.0029 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.1607 | 0.297 | 0.4252 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0049 | 0.0021 | 0.003 |
Schistosoma mansoni | cell adhesion molecule | 0.0049 | 0.0021 | 0.0021 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0141 | 0.0193 | 0.0267 |
Leishmania major | protein kinase, putative | 0.0608 | 0.1079 | 0.2614 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0415 | 0.0713 | 0.2393 |
Schistosoma mansoni | protein kinase | 0.0608 | 0.1079 | 0.1079 |
Schistosoma mansoni | cell adhesion molecule | 0.0237 | 0.0377 | 0.0377 |
Echinococcus multilocularis | neuroglian | 0.0049 | 0.0021 | 0.003 |
Echinococcus multilocularis | tyrosine protein kinase otk | 0.0045 | 0.0013 | 0.0019 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0828 | 0.1495 | 0.1495 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.1607 | 0.297 | 1 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.1265 | 0.2322 | 0.7816 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.1607 | 0.297 | 1 |
Echinococcus multilocularis | 0.0255 | 0.041 | 0.0587 | |
Schistosoma mansoni | septate junction protein | 0.0045 | 0.0013 | 0.0013 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0141 | 0.0193 | 0.0267 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.0328 | 0.1094 |
Echinococcus granulosus | basic fibroblast growth factor receptor 1 A | 0.0129 | 0.0171 | 0.0235 |
Loa Loa (eye worm) | CAMK/MLCK protein kinase | 0.0042 | 0.0007 | 0.0013 |
Leishmania major | cytochrome p450-like protein | 0.0415 | 0.0713 | 0.1185 |
Echinococcus multilocularis | neuroglian | 0.0235 | 0.0372 | 0.0532 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0255 | 0.041 | 0.5 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0608 | 0.1079 | 0.1536 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0828 | 0.1495 | 0.1495 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0255 | 0.041 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0255 | 0.041 | 0.5 |
Schistosoma mansoni | defective proboscis extension response (dpr)-related | 0.0211 | 0.0328 | 0.0328 |
Echinococcus granulosus | peroxidasin | 0.0046 | 0.0014 | 0.0009 |
Loa Loa (eye worm) | serotonin transporter b | 0.0828 | 0.1495 | 0.5027 |
Loa Loa (eye worm) | hypothetical protein | 0.0828 | 0.1495 | 0.5027 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0255 | 0.041 | 0.0577 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0415 | 0.0713 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0415 | 0.0713 | 0.2393 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0255 | 0.041 | 0.5 |
Echinococcus multilocularis | contactin neuroglian septate junction protein | 0.0049 | 0.0021 | 0.003 |
Brugia malayi | protein unc-22 | 0.0042 | 0.0007 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0414 | 0.1382 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0255 | 0.041 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1607 | 0.297 | 1 |
Onchocerca volvulus | Basement membrane proteoglycan homolog | 0.0045 | 0.0013 | 0.002 |
Brugia malayi | Prion-like- | 0.0045 | 0.0013 | 0.0033 |
Echinococcus multilocularis | Immunoglobulin | 0.0211 | 0.0328 | 0.0469 |
Brugia malayi | Cytochrome P450 family protein | 0.0415 | 0.0713 | 0.2393 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.1607 | 0.297 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0193 | 0.064 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0045 | 0.0013 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0345 | 0.058 | 0.1945 |
Schistosoma mansoni | cell adhesion molecule | 0.0049 | 0.0021 | 0.0021 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0141 | 0.0193 | 0.0193 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0608 | 0.1079 | 0.1545 |
Echinococcus multilocularis | roundabout 2 | 0.0049 | 0.0021 | 0.003 |
Echinococcus granulosus | receptor type tyrosine protein phosphatase | 0.0049 | 0.0021 | 0.0019 |
Onchocerca volvulus | 0.0141 | 0.0193 | 0.0628 | |
Giardia lamblia | Kinase, PLK | 0.1607 | 0.297 | 1 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0141 | 0.0193 | 0.064 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0828 | 0.1495 | 0.5027 |
Echinococcus granulosus | roundabout 2 | 0.0261 | 0.0421 | 0.0593 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0013 | 0.0033 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0255 | 0.041 | 0.2443 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0193 | 0.064 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0141 | 0.0193 | 0.0193 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0255 | 0.041 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1607 | 0.297 | 1 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0141 | 0.0193 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0215 | 0.0335 | 0.1117 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0193 | 0.064 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0608 | 0.1079 | 1 |
Onchocerca volvulus | 0.0828 | 0.1495 | 0.5021 | |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.1607 | 0.297 | 1 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0141 | 0.0193 | 0.0193 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0141 | 0.0193 | 0.064 |
Echinococcus multilocularis | basic fibroblast growth factor receptor 1 A | 0.0129 | 0.0171 | 0.0245 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0013 | 0.0033 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0255 | 0.041 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.0414 | 0.1382 |
Echinococcus granulosus | neuroglian | 0.0235 | 0.0372 | 0.0522 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0141 | 0.0193 | 0.064 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0045 | 0.0013 | 0.0033 |
Toxoplasma gondii | aurora kinase | 0.0608 | 0.1079 | 1 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0608 | 0.1079 | 0.3626 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0156 | 0.0222 | 0.0222 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0021 | 0.0058 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1607 | 0.297 | 1 |
Echinococcus granulosus | contactin | 0.0049 | 0.0021 | 0.0019 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0255 | 0.041 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0415 | 0.0713 | 0.2393 |
Echinococcus multilocularis | receptor type tyrosine protein phosphatase | 0.0049 | 0.0021 | 0.003 |
Echinococcus multilocularis | titin | 0.0042 | 0.0007 | 0.0011 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0013 | 0.0033 |
Brugia malayi | Peroxidasin | 0.0046 | 0.0014 | 0.0035 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0045 | 0.0013 | 0.0033 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0141 | 0.0193 | 0.0193 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0141 | 0.0193 | 0.0267 |
Loa Loa (eye worm) | immunoglobulin I-set domain-containing protein | 0.0049 | 0.0021 | 0.0058 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0013 | 0.0033 |
Loa Loa (eye worm) | hypothetical protein | 0.0828 | 0.1495 | 0.5027 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0045 | 0.0013 | 0.0033 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0255 | 0.041 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0415 | 0.0713 | 0.2393 |
Schistosoma mansoni | cytochrome P450 | 0.0255 | 0.041 | 0.041 |
Schistosoma mansoni | receptor tyrosine phosphatase type r2a | 0.0049 | 0.0021 | 0.0021 |
Brugia malayi | Cytochrome P450 family protein | 0.0996 | 0.1814 | 0.6102 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0049 | 0.0021 | 0.0058 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0049 | 0.0021 | 0.0058 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1607 | 0.297 | 1 |
Echinococcus multilocularis | lachesin | 0.0045 | 0.0013 | 0.0019 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0415 | 0.0713 | 0.1185 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0141 | 0.0193 | 0.064 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0255 | 0.041 | 0.5 |
Schistosoma mansoni | vesicular amine transporter | 0.0211 | 0.0328 | 0.0328 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0141 | 0.0193 | 0.0267 |
Echinococcus granulosus | serotonin transporter | 0.0828 | 0.1495 | 0.2132 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0193 | 0.064 |
Echinococcus multilocularis | Immunoglobulin | 0.0211 | 0.0328 | 0.0469 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0608 | 0.1079 | 0.1079 |
Schistosoma mansoni | neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule | 0.0045 | 0.0013 | 0.0013 |
Echinococcus granulosus | twitchin | 0.025 | 0.04 | 0.0563 |
Echinococcus granulosus | roundabout 2 | 0.0049 | 0.0021 | 0.0019 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0141 | 0.0193 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0255 | 0.041 | 0.5 |
Echinococcus granulosus | fibroblast growth factor receptor 4 | 0.0129 | 0.0171 | 0.0235 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.1607 | 0.297 | 0.4246 |
Trichomonas vaginalis | CAMK family protein kinase | 0.1607 | 0.297 | 1 |
Trypanosoma brucei | aurora B kinase | 0.0608 | 0.1079 | 0.2614 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0141 | 0.0193 | 0.0277 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0141 | 0.0193 | 0.064 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1607 | 0.297 | 0.297 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0828 | 0.1495 | 0.5027 |
Mycobacterium leprae | putative cytochrome p450 | 0.0255 | 0.041 | 0.5 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0828 | 0.1495 | 0.5027 |
Schistosoma mansoni | septate junction protein | 0.0045 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.0193 | 0.064 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0255 | 0.041 | 0.5 |
Echinococcus multilocularis | serotonin transporter | 0.0828 | 0.1495 | 0.214 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0045 | 0.0013 | 0.0033 |
Schistosoma mansoni | roundabout | 0.0045 | 0.0013 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0013 | 0.0033 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0141 | 0.0193 | 0.0277 |
Schistosoma mansoni | tyrosine kinase | 0.0067 | 0.0054 | 0.0054 |
Echinococcus granulosus | Serine:threonine protein kinase PLK4 | 0.3728 | 0.6986 | 1 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0828 | 0.1495 | 0.5 |
Echinococcus multilocularis | hemicentin 1 | 0.0045 | 0.0013 | 0.0019 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0141 | 0.0193 | 0.0193 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0255 | 0.041 | 0.5 |
Echinococcus multilocularis | peroxidasin | 0.0046 | 0.0014 | 0.002 |
Loa Loa (eye worm) | CAMK protein kinase | 0.0042 | 0.0007 | 0.0013 |
Onchocerca volvulus | 0.0141 | 0.0193 | 0.0628 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.