Detailed information for compound 835483

Basic information

Technical information
  • TDR Targets ID: 835483
  • Name: N-(2-ethoxyphenyl)-N'-(2-hydroxyethyl)oxamide
  • MW: 252.266 | Formula: C12H16N2O4
  • H donors: 3 H acceptors: 3 LogP: 0.46 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: OCCNC(=O)C(=O)Nc1ccccc1OCC
  • InChi: 1S/C12H16N2O4/c1-2-18-10-6-4-3-5-9(10)14-12(17)11(16)13-7-8-15/h3-6,15H,2,7-8H2,1H3,(H,13,16)(H,14,17)
  • InChiKey: BHHVNZXIXAGJIC-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(2-ethoxyphenyl)-N'-(2-hydroxyethyl)ethanediamide
  • 6065-02-7
  • BIM-0021183.P001
  • CBMicro_021217
  • ZINC02944608

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei Dipeptidyl-peptidase 8-like, putative 0.0116 0.0387 0.0702
Brugia malayi SH2 domain containing protein 0.0018 0.0014 0.0014
Echinococcus granulosus cathepsin L 0.0283 0.1025 0.1012
Toxoplasma gondii hypothetical protein 0.0027 0.0049 0.0095
Echinococcus multilocularis hypothetical protein 0.0021 0.0024 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0047 0.0047
Toxoplasma gondii cathepsin CPC1 0.0229 0.0821 0.2212
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0031 0.0063 0.0049
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0116 0.0115
Trypanosoma brucei antigen, putative 0.0021 0.0024 0.0043
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0031 0.0063 0.0049
Entamoeba histolytica hypothetical protein 0.0024 0.0037 0.014
Echinococcus granulosus cathepsin l1 0.069 0.2581 0.257
Onchocerca volvulus 0.069 0.2581 1
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0038 0.0092
Schistosoma mansoni hypothetical protein 0.0314 0.1146 0.1133
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0014 0.0014
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Brugia malayi Sex muscle abnormal protein 5 0.0018 0.0014 0.0014
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0031 0.0063 0.0049
Schistosoma mansoni inhibitor of apoptosis protein 0.0178 0.0625 0.0611
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0229 0.0821 0.2184
Onchocerca volvulus 0.069 0.2581 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0063 0.0063
Echinococcus granulosus microtubule associated protein 2 0.0696 0.2605 0.2595
Echinococcus multilocularis tyrosine protein kinase Abl 0.0031 0.0063 0.0049
Echinococcus granulosus tyrosine protein kinase Src42A 0.0031 0.0063 0.0049
Leishmania major cathepsin L-like protease 0.069 0.2581 0.4687
Echinococcus multilocularis tar DNA binding protein 0.0063 0.0186 0.0172
Echinococcus granulosus TGF beta signal transducer SmadC 0.0024 0.0036 0.0022
Loa Loa (eye worm) hypothetical protein 0.0744 0.2787 0.2787
Brugia malayi Cathepsin L-like precursor 0.069 0.2581 0.2581
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0229 0.0821 0.0821
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0047 0.0047
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0053 0.0149 0.0149
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0045 0.0116 0.0116
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2631 1 1
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0031 0.0063 0.0049
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0049 0.019
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0229 0.0821 0.0808
Echinococcus multilocularis musashi 0.0027 0.0047 0.0033
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Schistosoma mansoni hypothetical protein 0.0405 0.1492 0.1479
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0229 0.0821 0.3143
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Trypanosoma brucei serine peptidase, Clan SC, Family S9B 0.0116 0.0387 0.0702
Echinococcus multilocularis lamin 0.0027 0.0047 0.0033
Echinococcus granulosus histone deacetylase 6 0.0045 0.0116 0.0101
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0037 0.0023
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0058 0.0104
Loa Loa (eye worm) calpain 0.0021 0.0024 0.0024
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0022 0.0028 0.0028
Schistosoma mansoni dipeptidyl-peptidase 9 (S09 family) 0.0116 0.0387 0.0373
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0229 0.0821 0.0821
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0283 0.1025 0.1012
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0024 0.0024
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0024 0.0043
Onchocerca volvulus 0.0018 0.0015 0.0002
Schistosoma mansoni tyrosine kinase 0.0031 0.0063 0.0049
Loa Loa (eye worm) TK/ROR protein kinase 0.0031 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0178 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Schistosoma mansoni acylaminoacyl-peptidase (S09 family) 0.0027 0.0049 0.0035
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0229 0.0821 0.0808
Leishmania major importin beta-1 subunit, putative 0.0024 0.0037 0.0065
Mycobacterium ulcerans protease II (oligopeptidase B), PtrB 0.0027 0.0049 0.5
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Entamoeba histolytica cysteine proteinase 2 0.0283 0.1025 0.3972
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0058 0.0104
Echinococcus granulosus lamin 0.0027 0.0047 0.0033
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Plasmodium falciparum serine repeat antigen 4 0.0229 0.0821 0.3143
Echinococcus granulosus tyrosine protein kinase Srms 0.0031 0.0063 0.0049
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0972 0.366 0.366
Schistosoma mansoni smad1 5 8 and 0.0024 0.0036 0.0022
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0027 0.0049 0.0089
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.0461 0.0448
Schistosoma mansoni hypothetical protein 0.0047 0.0123 0.0109
Onchocerca volvulus 0.0031 0.0063 0.0189
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0031 0.0063 0.0049
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0014 0.0014
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0229 0.0821 0.0808
Trypanosoma brucei histone deacetylase 4 0.0045 0.0116 0.0209
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0054 0.0054
Onchocerca volvulus Cell death protein 3 homolog 0.0095 0.031 0.1152
Plasmodium falciparum cysteine proteinase falcipain 3 0.069 0.2581 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Leishmania major hypothetical protein, conserved 0.0024 0.0038 0.0069
Brugia malayi Histone deacetylase family protein 0.0045 0.0116 0.0116
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0229 0.0821 0.3143
Trypanosoma cruzi serine peptidase, Clan SC, Family S9B 0.0116 0.0387 0.0386
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0049 0.0049
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.0027 0.0049 0.0049
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0047 0.0047
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0178 0.0625 0.0625
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0821 0.2184
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0031 0.0063 0.0049
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0031 0.0063 0.0049
Schistosoma mansoni ran 0.0022 0.0028 0.0014
Trypanosoma brucei oligopeptidase b 0.0027 0.0049 0.0089
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0229 0.0821 0.0808
Trypanosoma cruzi prolyl endopeptidase 0.0027 0.0049 0.0049
Echinococcus multilocularis apoptotic protease activating factor 1 0.0095 0.031 0.0296
Entamoeba histolytica cysteine protease, putative 0.0229 0.0821 0.3181
Echinococcus granulosus apoptotic protease activating factor 1 0.0095 0.031 0.0296
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0116 0.0101
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0055 0.0154 0.014
Echinococcus granulosus Smad4 0.0024 0.0036 0.0022
Schistosoma mansoni Mername-AA248 (C02 family) 0.0021 0.0024 0.001
Loa Loa (eye worm) gamma-secretase subunit aph-1 0.0254 0.0914 0.0914
Brugia malayi hypothetical protein 0.0016 0.0005 0.0005
Giardia lamblia Cathepsin B precursor 0.0229 0.0821 0.2184
Plasmodium falciparum serine repeat antigen 5 0.0229 0.0821 0.3143
Loa Loa (eye worm) cytochrome P450 family protein 0.0022 0.0029 0.0029
Toxoplasma gondii preprocathepsin c precursor, putative 0.0229 0.0821 0.2212
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0014 0.0014
Onchocerca volvulus 0.0031 0.0063 0.0189
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0229 0.0821 0.2184
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0057 0.0164 0.015
Loa Loa (eye worm) hypothetical protein 0.0229 0.0821 0.0821
Brugia malayi Papain family cysteine protease containing protein 0.0229 0.0821 0.0821
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Schistosoma mansoni microtubule-associated protein tau 0.0696 0.2605 0.2595
Echinococcus multilocularis mothers against decapentaplegic 5 0.0024 0.0036 0.0022
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0024 0.0024
Plasmodium falciparum importin beta, putative 0.0029 0.0058 0.0167
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0021 0.0024 0.0024
Brugia malayi MH2 domain containing protein 0.0024 0.0036 0.0036
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.0461 0.0448
Onchocerca volvulus 0.0028 0.0054 0.0154
Echinococcus granulosus snurportin 1 0.0314 0.1146 0.1133
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0027 0.0049 0.0049
Schistosoma mansoni survival motor neuron protein 0.0047 0.0123 0.0109
Schistosoma mansoni inhibitor of apoptosis (iap) domain family member 0.0178 0.0625 0.0611
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0461 0.0448
Trypanosoma cruzi cysteine peptidase, putative 0.0053 0.0149 0.0149
Giardia lamblia Alanyl dipeptidyl peptidase 0.0027 0.0049 0.0059
Schistosoma mansoni tyrosine kinase 0.0031 0.0063 0.0049
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0024 0.0043
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0024 0.001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0049 0.0049
Leishmania major cathepsin L-like protease 0.0884 0.3324 0.6038
Schistosoma mansoni histone deacetylase 4 5 0.0045 0.0116 0.0101
Trypanosoma brucei prolyl endopeptidase 0.0027 0.0049 0.0089
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0031 0.0063 0.0049
Echinococcus granulosus tyrosine kinase 0.0031 0.0063 0.0049
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0047 0.0047
Brugia malayi Cytochrome P450 family protein 0.0022 0.0029 0.0029
Echinococcus multilocularis cathepsin l cysteine peptidase 0.069 0.2581 0.257
Schistosoma mansoni cpg binding protein 0.003 0.006 0.0046
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0323 0.0322
Echinococcus multilocularis acylamino acid releasing enzyme 0.0027 0.0049 0.0035
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0151 0.0373
Echinococcus granulosus caspase 2 0.0095 0.031 0.0296
Echinococcus multilocularis baculoviral IAP repeat containing protein 0.0178 0.0625 0.0611
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0636 0.2377 0.6466
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.02 0.0185
Brugia malayi Protein kinase domain containing protein 0.0031 0.0063 0.0063
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0024 0.0043
Schistosoma mansoni P2X receptor subunit 0.0067 0.02 0.0185
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0229 0.0821 0.0808
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0972 0.366 0.3651
Loa Loa (eye worm) hypothetical protein 0.0228 0.0818 0.0818
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0461 0.0448
Brugia malayi SH2 domain containing protein 0.0018 0.0014 0.0014
Echinococcus multilocularis lamin dm0 0.0027 0.0047 0.0033
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0027 0.0049 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Brugia malayi ERG2 and Sigma1 receptor like protein 0.1455 0.5505 0.5505
Schistosoma mansoni cathepsin F (C01 family) 0.069 0.2581 0.257
Schistosoma mansoni histone deacetylase 4 5 0.0045 0.0116 0.0101
Giardia lamblia Cathepsin L precursor 0.0229 0.0821 0.2184
Schistosoma mansoni hypothetical protein 0.0667 0.2495 0.2484
Entamoeba histolytica cysteine protease, putative 0.0229 0.0821 0.3181
Echinococcus multilocularis histone deacetylase 7 0.0045 0.0116 0.0101
Giardia lamblia Cysteine protease 0.0229 0.0821 0.2184
Brugia malayi Cathepsin L-like precursor 0.0636 0.2377 0.2377
Echinococcus granulosus calpain 0.0021 0.0024 0.001
Onchocerca volvulus 0.0636 0.2377 0.9205
Brugia malayi tRNA modification GTPase TrmE family protein 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0034 0.0076 0.0076
Plasmodium falciparum serine repeat antigen 3 0.0229 0.0821 0.3143
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0024 0.0024
Plasmodium vivax histone deacetylase 2, putative 0.0045 0.0116 0.0393
Onchocerca volvulus 0.0047 0.0123 0.0425
Giardia lamblia Cathepsin B precursor 0.0229 0.0821 0.2184
Entamoeba histolytica cysteine proteinase, putative 0.0283 0.1025 0.3972
Loa Loa (eye worm) hypothetical protein 0.0088 0.0283 0.0283
Brugia malayi calpain family protein 1 0.0055 0.0154 0.0154
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0018 0.0014 0.0014
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Schistosoma mansoni tyrosine kinase 0.0031 0.0063 0.0049
Plasmodium vivax unspecified product 0.0283 0.1025 0.3938
Brugia malayi SRC-1 0.0031 0.0063 0.0063
Echinococcus multilocularis dipeptidyl aminopeptidaseprotein 0.0344 0.1258 0.1246
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0283 0.1025 0.2745
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0229 0.0821 0.3143
Echinococcus multilocularis tyrosine kinase 0.0031 0.0063 0.0049
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0135 0.0461 0.0461
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0229 0.0821 0.0808
Giardia lamblia Cathepsin B precursor 0.0972 0.366 1
Entamoeba histolytica Ran family GTPase 0.0022 0.0028 0.0107
Brugia malayi MH2 domain containing protein 0.0024 0.0036 0.0036
Echinococcus multilocularis dnaJ subfamily B 0.0405 0.1492 0.1479
Schistosoma mansoni lamin 0.0027 0.0047 0.0033
Loa Loa (eye worm) Smad1 0.0024 0.0036 0.0036
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0031 0.0063 0.0049
Echinococcus granulosus geminin 0.0667 0.2495 0.2484
Onchocerca volvulus 0.0027 0.0047 0.0128
Leishmania major GTP-binding protein, putative 0.0022 0.0028 0.005
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0229 0.0821 0.2184
Loa Loa (eye worm) MH2 domain-containing protein 0.0349 0.1279 0.1279
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0024 0.0036 0.0022
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0186 0.0172
Entamoeba histolytica cysteine proteinase, putative 0.0636 0.2377 0.9209
Brugia malayi calpain 7 0.0021 0.0024 0.0024
Giardia lamblia Cathepsin L precursor 0.0229 0.0821 0.2184
Echinococcus granulosus inhibitor of apoptosis protein 0.0178 0.0625 0.0611
Schistosoma mansoni tyrosine kinase 0.0031 0.0063 0.0049
Brugia malayi cathepsin F-like cysteine proteinase 0.0229 0.0821 0.0821
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0049 0.0049
Onchocerca volvulus Deterin homolog 0.0178 0.0625 0.2378
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2631 1 1
Entamoeba histolytica cysteine protease, putative 0.0229 0.0821 0.3181
Onchocerca volvulus Prolyl endopeptidase homolog 0.0027 0.0049 0.0136
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.2631 1 1
Loa Loa (eye worm) hypothetical protein 0.0049 0.0131 0.0131
Echinococcus granulosus smad 0.0024 0.0036 0.0022
Trypanosoma cruzi cysteine proteinase, putative 0.0283 0.1025 0.1025
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0022 0.0028 0.0028
Plasmodium vivax importin-beta 2, putative 0.0029 0.0058 0.0167
Brugia malayi MH1 domain containing protein 0.0024 0.0036 0.0036
Trichomonas vaginalis conserved hypothetical protein 0.0229 0.0821 0.2184
Loa Loa (eye worm) hypothetical protein 0.0053 0.0149 0.0149
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0229 0.0821 0.3143
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0037 0.0023
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0024 0.0043
Schistosoma mansoni hypothetical protein 0.0667 0.2495 0.2484
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0636 0.2377 0.6466
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0229 0.0821 0.2184
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0024 0.0024
Brugia malayi Cell death protein 3 precursor 0.0095 0.031 0.031
Brugia malayi Tyrosine-protein kinase abl-1 0.0031 0.0063 0.0063
Schistosoma mansoni cathepsin F (C01 family) 0.069 0.2581 0.257
Plasmodium falciparum histone deacetylase, putative 0.0045 0.0116 0.0393
Trypanosoma brucei Alpha/beta hydrolase domain-containing protein 0.0027 0.0049 0.0089
Echinococcus multilocularis tyrosine protein kinase Blk 0.0031 0.0063 0.0049
Trypanosoma cruzi cysteine peptidase, putative 0.0884 0.3324 0.3324
Trypanosoma cruzi C-8 sterol isomerase, putative 0.1455 0.5505 0.5505
Onchocerca volvulus 0.069 0.2581 1
Entamoeba histolytica cysteine proteinase, putative 0.0283 0.1025 0.3972
Brugia malayi prolyl oligopeptidase family protein 0.0027 0.0049 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0229 0.0821 0.2184
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0821 0.2184
Loa Loa (eye worm) MH1 domain-containing protein 0.0024 0.0036 0.0036
Giardia lamblia Cathepsin L precursor 0.0229 0.0821 0.2184
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0024 0.0043
Plasmodium vivax unspecified product 0.0229 0.0821 0.3143
Leishmania major cathepsin L-like protease 0.0884 0.3324 0.6038
Brugia malayi Papain family cysteine protease containing protein 0.0283 0.1025 0.1025
Echinococcus multilocularis calpain 5 0.0021 0.0024 0.001
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0028 0.0028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0027 0.0049 0.0049
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0831 0.312 0.312
Plasmodium falciparum cysteine proteinase falcipain 2a 0.069 0.2581 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Leishmania major cathepsin L-like protease 0.069 0.2581 0.4687
Echinococcus granulosus tar DNA binding protein 0.0063 0.0186 0.0172
Toxoplasma gondii acylaminoacyl-peptidase, putative 0.0027 0.0049 0.0095
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0031 0.0063 0.0049
Toxoplasma gondii dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein 0.0116 0.0387 0.102
Echinococcus granulosus tyrosine protein kinase Fyn 0.0031 0.0063 0.0049
Echinococcus granulosus cathepsin L cysteine proteinase 0.069 0.2581 0.257
Brugia malayi cathepsin L-like cysteine proteinase 0.0229 0.0821 0.0821
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0229 0.0821 0.2184
Giardia lamblia Cathepsin B precursor 0.0229 0.0821 0.2184
Brugia malayi protein-tyrosine kinase 0.0031 0.0063 0.0063
Echinococcus granulosus Dipeptidyl peptidase 9 0.0116 0.0387 0.0373
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0018 0.0014 0.0014
Echinococcus granulosus importin subunit beta 1 0.0029 0.0058 0.0043
Giardia lamblia Cathepsin B precursor 0.0229 0.0821 0.2184
Onchocerca volvulus Cathepsin L homolog 0.0229 0.0821 0.3144
Echinococcus multilocularis cathepsin b 0.2631 1 1
Leishmania major dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B 0.0116 0.0387 0.0702
Trichomonas vaginalis Clan SC, family S33, methylesterase-like serine peptidase 0.0027 0.0049 0.0059
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0038 0.0092
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0229 0.0821 0.3143
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.069 0.2581 0.7028
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0186 0.0172
Giardia lamblia Alanyl dipeptidyl peptidase 0.0027 0.0049 0.0059
Trypanosoma cruzi oligopeptidase b 0.0027 0.0049 0.0049
Echinococcus granulosus histone deacetylase 6 0.0045 0.0116 0.0101
Brugia malayi CXXC zinc finger family protein 0.0028 0.0054 0.0054
Schistosoma mansoni hypothetical protein 0.0178 0.0625 0.0611
Trypanosoma cruzi cruzipain precursor, putative 0.0884 0.3324 0.3324
Mycobacterium tuberculosis Probable protease II PtrBb [second part] (oligopeptidase B) 0.0027 0.0049 0.5
Onchocerca volvulus Dipeptidyl peptidase family member 1 homolog 0.0344 0.1258 0.4847
Brugia malayi Importin beta-1 subunit 0.0029 0.0058 0.0058
Brugia malayi calpain family protein 1 0.0055 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0022 0.0028 0.0051
Entamoeba histolytica cysteine proteinase, putative 0.069 0.2581 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0024 0.0024
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0116 0.0101
Brugia malayi RNA, U transporter 1 0.0084 0.0265 0.0265
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0186 0.0172
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0821 0.2184
Echinococcus granulosus calpain A 0.0021 0.0024 0.001
Entamoeba histolytica hypothetical protein, conserved 0.0027 0.0049 0.019
Onchocerca volvulus 0.0031 0.0063 0.0189
Brugia malayi hypothetical protein 0.0095 0.031 0.031
Giardia lamblia Cathepsin L precursor 0.0229 0.0821 0.2184
Entamoeba histolytica cysteine protease, putative 0.0229 0.0821 0.3181
Trypanosoma cruzi cysteine peptidase, putative 0.069 0.2581 0.258
Echinococcus multilocularis calpain 7 (C02 family) 0.0021 0.0024 0.001
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0229 0.0821 0.0808
Echinococcus multilocularis cathepsin L 0.0283 0.1025 0.1012
Loa Loa (eye worm) hypothetical protein 0.0178 0.0625 0.0625
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.1025 0.1862
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.0027 0.0049 0.0089
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0135 0.0461 0.0461
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0821 0.2184
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0283 0.1025 0.1012
Mycobacterium tuberculosis Probable peptidase 0.0027 0.0049 0.5
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0229 0.0821 0.3143
Brugia malayi Inhibitor of Apoptosis domain containing protein 0.0178 0.0625 0.0625
Plasmodium vivax hypothetical protein, conserved 0.0027 0.0049 0.0134
Entamoeba histolytica SH2 domain containing protein 0.0018 0.0014 0.0054
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0038 0.0038
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0018 0.0014 0.0014
Brugia malayi Protein kinase domain containing protein 0.0031 0.0063 0.0063
Echinococcus multilocularis calpain A 0.0057 0.0164 0.015
Echinococcus multilocularis cathepsin b 0.2631 1 1
Giardia lamblia Encystation-specific protease 0.0229 0.0821 0.2184
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.2631 1 1
Brugia malayi cathepsin L-like precursor 0.0636 0.2377 0.2377
Schistosoma mansoni P2X receptor subunit 0.0067 0.02 0.0185
Entamoeba histolytica cysteine protease, putative 0.069 0.2581 1
Echinococcus granulosus dnaJ subfamily B 0.0405 0.1492 0.1479
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0038 0.0092
Plasmodium falciparum peptidase, putative 0.0027 0.0049 0.0134
Onchocerca volvulus 0.0178 0.0625 0.2378
Echinococcus multilocularis smad 0.0024 0.0036 0.0022
Brugia malayi cathepsin Z-like cysteine proteinase 0.0229 0.0821 0.0821
Leishmania major cathepsin L-like protease 0.069 0.2581 0.4687
Onchocerca volvulus 0.0031 0.0063 0.0189
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Echinococcus multilocularis prolyl endopeptidase 0.0027 0.0049 0.0035
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0135 0.0461 0.0448
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0229 0.0821 0.2184
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0031 0.0063 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0229 0.0821 0.2184
Leishmania major hypothetical protein, conserved 0.0018 0.0015 0.0026
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Loa Loa (eye worm) prolyl oligopeptidase 0.0344 0.1258 0.1258
Echinococcus granulosus cpg binding protein 0.003 0.006 0.0046
Plasmodium vivax serine-repeat antigen (SERA) 0.0229 0.0821 0.3143
Entamoeba histolytica cysteine protease, putative 0.0229 0.0821 0.3181
Echinococcus multilocularis calpain 0.0021 0.0024 0.001
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0022 0.0028 0.0028
Brugia malayi Papain family cysteine protease containing protein 0.069 0.2581 0.2581
Schistosoma mansoni hypothetical protein 0.0095 0.031 0.0296
Echinococcus granulosus c src tyrosine kinase 0.0031 0.0063 0.0049
Brugia malayi cathepsin L precursor 0.0229 0.0821 0.0821
Giardia lamblia Cysteine protease 0.0229 0.0821 0.2184
Echinococcus multilocularis histone deacetylase 6 0.0045 0.0116 0.0101
Brugia malayi Cathepsin L-like precursor 0.069 0.2581 0.2581
Brugia malayi Papain family cysteine protease containing protein 0.0229 0.0821 0.0821
Entamoeba histolytica hypothetical protein 0.0229 0.0821 0.3181
Brugia malayi hypothetical protein 0.0088 0.0283 0.0283
Onchocerca volvulus 0.069 0.2581 1
Trypanosoma cruzi cysteine proteinase, putative 0.0283 0.1025 0.1025
Echinococcus granulosus tyrosine protein kinase Src64B 0.0031 0.0063 0.0049
Toxoplasma gondii cathepsin B 0.0972 0.366 1
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0229 0.0821 0.3143
Loa Loa (eye worm) histone deacetylase 0.0045 0.0116 0.0116
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0283 0.1025 0.1025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0283 0.1025 0.1012
Loa Loa (eye worm) hypothetical protein 0.0229 0.0821 0.0821
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Loa Loa (eye worm) hypothetical protein 0.0029 0.0058 0.0058
Giardia lamblia Hypothetical protein 0.0229 0.0821 0.2184
Onchocerca volvulus 0.0031 0.0063 0.0189
Loa Loa (eye worm) SH2 domain-containing protein 0.0018 0.0014 0.0014
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0229 0.0821 0.3143
Echinococcus multilocularis snurportin 1 0.0314 0.1146 0.1133
Loa Loa (eye worm) calpain 5 0.0014 0.0001 0.0001
Plasmodium vivax histone deacetylase, putative 0.0045 0.0116 0.0393
Echinococcus granulosus cysteine protease 0.0283 0.1025 0.1012
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0031 0.0063 0.0049
Echinococcus multilocularis histone deacetylase 0.0045 0.0116 0.0101
Brugia malayi RhoGAP domain containing protein 0.0018 0.0014 0.0014
Echinococcus granulosus cathepsin L 0.0229 0.0821 0.0808
Brugia malayi calpain 5 0.0014 0.0001 0.0001
Plasmodium vivax vivapain-2 0.069 0.2581 1
Loa Loa (eye worm) hypothetical protein 0.0027 0.0049 0.0049
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0229 0.0821 0.0808
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0024 0.0036 0.0022
Plasmodium falciparum serine repeat antigen 1 0.0229 0.0821 0.3143
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0037 0.0023
Onchocerca volvulus 0.069 0.2581 1
Trypanosoma brucei histone deacetylase 3 0.0045 0.0116 0.0209
Loa Loa (eye worm) fibroinase 0.069 0.2581 0.2581
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0972 0.366 0.6648
Brugia malayi Histone deacetylase family protein 0.0045 0.0116 0.0116
Plasmodium falciparum serine repeat antigen 7 0.0229 0.0821 0.3143
Giardia lamblia Cathepsin L precursor 0.0229 0.0821 0.2184
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0038 0.0064
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Plasmodium falciparum serine repeat antigen 2 0.0229 0.0821 0.3143
Echinococcus granulosus calpain 7 C02 family 0.0021 0.0024 0.001
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0022 0.0028 0.005
Echinococcus granulosus cathepsin b 0.2631 1 1
Brugia malayi Protein kinase domain containing protein 0.0031 0.0063 0.0063
Toxoplasma gondii prolyl endopeptidase 0.0027 0.0049 0.0095
Brugia malayi Cathepsin L-like precursor 0.0636 0.2377 0.2377
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0821 0.2184
Loa Loa (eye worm) hypothetical protein 0.0053 0.0149 0.0149
Loa Loa (eye worm) cathepsin B 0.0972 0.366 0.366
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0022 0.0028 0.0014
Leishmania major histone deacetylase, putative 0.0045 0.0116 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0229 0.0821 0.2184
Leishmania major cathepsin L-like protease 0.069 0.2581 0.4687
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0821 0.2184
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0018 0.0014 0.0014
Trypanosoma brucei C-8 sterol isomerase, putative 0.1455 0.5505 1
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.0164 0.015
Echinococcus granulosus lamin dm0 0.0027 0.0047 0.0033
Schistosoma mansoni histone deacetylase hda2 0.0045 0.0116 0.0101
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0229 0.0821 0.3143
Entamoeba histolytica cysteine proteinase, putative 0.069 0.2581 1
Leishmania major cathepsin L-like protease 0.0884 0.3324 0.6038
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0022 0.0028 0.0036
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Schistosoma mansoni calpain (C02 family) 0.0021 0.0024 0.001
Plasmodium vivax vivapain-2 0.069 0.2581 1
Plasmodium falciparum histone deacetylase 2 0.0045 0.0116 0.0393
Onchocerca volvulus 0.0095 0.031 0.1152
Loa Loa (eye worm) calpain family protein 1 0.004 0.0099 0.0099
Loa Loa (eye worm) SRC-1 0.0031 0.0063 0.0063
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0027 0.0049 0.0035
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0135 0.0461 0.0448
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.02 0.0185
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0229 0.0821 0.3181
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Onchocerca volvulus 0.069 0.2581 1
Leishmania major oligopeptidase b 0.0027 0.0049 0.0089
Schistosoma mansoni cathepsin C 0.0229 0.0821 0.0808
Echinococcus multilocularis cathepsin L cysteine protease 0.069 0.2581 0.257
Trypanosoma cruzi cysteine protease, putative 0.0283 0.1025 0.1025
Brugia malayi Kringle domain containing protein 0.0018 0.0015 0.0015
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0049 0.019
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0024 0.0024
Brugia malayi TAR-binding protein 0.0063 0.0186 0.0186
Trypanosoma brucei calpain-like protein, putative 0.0021 0.0024 0.0043
Plasmodium vivax vivapain-1 0.0283 0.1025 0.3938
Echinococcus granulosus gamma secretase subunit aph 1 0.0254 0.0914 0.0901
Brugia malayi Tensin 0.0018 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0636 0.2377 0.2377
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0057 0.0164 0.015
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0229 0.0821 0.2184
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0038 0.0038
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.0186 0.0186
Echinococcus granulosus calpain 5 0.0021 0.0024 0.001
Echinococcus multilocularis geminin 0.0667 0.2495 0.2484
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Schistosoma mansoni gamma-secretase subunit aph-1 0.0254 0.0914 0.0901
Onchocerca volvulus 0.0034 0.0076 0.0238
Onchocerca volvulus 0.0031 0.0063 0.0189
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0049 0.0049
Brugia malayi Protein kinase domain containing protein 0.0031 0.0063 0.0063
Entamoeba histolytica cysteine proteinase, putative 0.0283 0.1025 0.3972
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0031 0.0063 0.0049
Brugia malayi fibroinase precursor 0.0229 0.0821 0.0821
Trypanosoma cruzi cysteine peptidase, putative 0.0283 0.1025 0.1025
Echinococcus multilocularis cpg binding protein 0.003 0.006 0.0046
Brugia malayi Papain family cysteine protease containing protein 0.0229 0.0821 0.0821
Echinococcus granulosus survival motor neuron protein 1 0.0228 0.0818 0.0805
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0038 0.0069
Schistosoma mansoni cathepsin F (C01 family) 0.0636 0.2377 0.2366
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Entamoeba histolytica cysteine proteinase 1, putative 0.0283 0.1025 0.3972
Schistosoma mansoni smad1 5 8 and 0.0024 0.0036 0.0022
Trypanosoma cruzi cruzipain precursor, putative 0.0053 0.0149 0.0149
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0053 0.0149 0.0149
Toxoplasma gondii cathepsin CPL 0.069 0.2581 0.7039
Loa Loa (eye worm) hypothetical protein 0.0229 0.0821 0.0821
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.02 0.0185
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0057 0.0164 0.015
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0031 0.0063 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0018 0.0015 0.0014
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0027 0.0049 0.0089
Echinococcus multilocularis inhibitor of apoptosis protein 0.0178 0.0625 0.0611
Loa Loa (eye worm) hypothetical protein 0.2631 1 1
Brugia malayi hypothetical protein 0.0024 0.0038 0.0038
Trypanosoma cruzi Aph-1 protein, putative 0.0099 0.0323 0.0322
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.02 0.0185
Entamoeba histolytica cysteine protease, putative 0.0229 0.0821 0.3181
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0031 0.0063 0.0049
Trypanosoma cruzi major cysteine proteinase, putative 0.0229 0.0821 0.0821
Brugia malayi hypothetical protein 0.0031 0.0063 0.0063
Schistosoma mansoni cpg binding protein 0.003 0.006 0.0046
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0018 0.0014 0.0054
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0821 0.2184
Loa Loa (eye worm) calpain family protein 1 0.0055 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.069 0.2581 0.2581
Schistosoma mansoni smad1 5 8 and 0.0024 0.0036 0.0022
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0024 0.0024
Schistosoma mansoni P2X receptor subunit 0.0067 0.02 0.0185
Trichomonas vaginalis Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase 0.0027 0.0049 0.0059
Schistosoma mansoni subfamily S9B unassigned peptidase (S09 family) 0.0344 0.1258 0.1246
Giardia lamblia Cysteine protease 0.0229 0.0821 0.2184
Echinococcus multilocularis Dipeptidyl peptidase 9 0.0116 0.0387 0.0373
Echinococcus granulosus mothers against decapentaplegic 5 0.0024 0.0036 0.0022
Echinococcus granulosus dipeptidyl aminopeptidaseprotein 0.0344 0.1258 0.1246
Toxoplasma gondii histone deacetylase HDAC1 0.0045 0.0116 0.0276
Loa Loa (eye worm) hypothetical protein 0.0095 0.031 0.031
Toxoplasma gondii cathepsin CPC2 0.0229 0.0821 0.2212
Loa Loa (eye worm) TAR-binding protein 0.0063 0.0186 0.0186
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0176 0.0161
Schistosoma mansoni intermediate filament proteins 0.0027 0.0047 0.0033
Echinococcus multilocularis cysteine protease 0.069 0.2581 0.257
Schistosoma mansoni caspase-7 (C14 family) 0.0095 0.031 0.0296
Echinococcus granulosus calpain A 0.0057 0.0164 0.015
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0024 0.0043
Giardia lamblia Cathepsin B precursor 0.0972 0.366 1
Echinococcus multilocularis cysteine protease 0.069 0.2581 0.257
Brugia malayi Cathepsin L-like precursor 0.069 0.2581 0.2581
Loa Loa (eye worm) SH2 domain-containing protein 0.0018 0.0014 0.0014
Brugia malayi SH2 domain containing protein 0.0018 0.0014 0.0014
Trypanosoma cruzi dipeptidyl-peptidase 8-like serine peptidase 0.0116 0.0387 0.0386
Loa Loa (eye worm) hypothetical protein 0.1455 0.5505 0.5505
Brugia malayi cytokine inducible SH2-containing protein 5 0.0018 0.0014 0.0014
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Loa Loa (eye worm) hypothetical protein 0.0045 0.0116 0.0116
Loa Loa (eye worm) TK protein kinase 0.0031 0.0063 0.0063
Brugia malayi Cathepsin L-like precursor 0.0053 0.0149 0.0149
Schistosoma mansoni P2X receptor subunit 0.0067 0.02 0.0185
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0058 0.0043
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Entamoeba histolytica cysteine proteinase, putative 0.0283 0.1025 0.3972
Brugia malayi MH1 domain containing protein 0.0024 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Leishmania major cysteine peptidase A (CPA) 0.069 0.2581 0.4687
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0229 0.0821 0.3143
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0014 0.0014
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0229 0.0821 0.2184
Plasmodium falciparum serine repeat antigen 9 0.0229 0.0821 0.3143
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0186 0.0172
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Brugia malayi Protein kinase domain containing protein 0.0031 0.0063 0.0063
Echinococcus granulosus tyrosine protein kinase Fyn 0.0031 0.0063 0.0049
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0123 0.0123
Brugia malayi Cathepsin L-like precursor 0.069 0.2581 0.2581
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0027 0.0049 0.019
Loa Loa (eye worm) transcription factor SMAD2 0.0349 0.1279 0.1279
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0031 0.0063 0.0049
Loa Loa (eye worm) hypothetical protein 0.0053 0.0149 0.0149
Plasmodium vivax serine-repeat antigen (SERA) 0.0229 0.0821 0.3143
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Brugia malayi SH2 domain containing protein 0.0018 0.0014 0.0014
Echinococcus multilocularis p2X purinoceptor 4 0.0067 0.02 0.0185
Loa Loa (eye worm) TK/ABL protein kinase 0.0031 0.0063 0.0063
Brugia malayi MH2 domain containing protein 0.0349 0.1279 0.1279
Brugia malayi SH2 domain containing protein 0.0018 0.0014 0.0014
Brugia malayi Cathepsin L-like cysteine proteinase 0.0636 0.2377 0.2377
Brugia malayi cathepsin F-like cysteine proteinase 0.0053 0.0149 0.0149
Brugia malayi intermediate filament protein 0.0027 0.0047 0.0047
Onchocerca volvulus 0.0229 0.0821 0.3144
Trypanosoma brucei histone deacetylase, putative 0.0045 0.0116 0.0209
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0031 0.0063 0.0049
Trypanosoma cruzi hypothetical protein, conserved 0.0027 0.0049 0.0049
Schistosoma mansoni tar DNA-binding protein 0.0063 0.0186 0.0172
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0049 0.0059
Schistosoma mansoni lamin 0.0027 0.0047 0.0033
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.069 0.2581 0.2581
Echinococcus granulosus prolyl endopeptidase 0.0027 0.0049 0.0035
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Echinococcus granulosus cathepsin L cysteine protease 0.0283 0.1025 0.1012
Schistosoma mansoni Smad4 0.0024 0.0036 0.0022
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0031 0.0063 0.0049
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0229 0.0821 0.3143
Brugia malayi Protein kinase domain containing protein 0.0031 0.0063 0.0063
Brugia malayi RNA binding protein 0.0063 0.0186 0.0186
Echinococcus multilocularis gamma secretase subunit aph 1 0.0254 0.0914 0.0901
Schistosoma mansoni calpain C (C02 family) 0.0021 0.0024 0.001
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Trypanosoma cruzi cysteine peptidase, putative 0.0884 0.3324 0.3324
Echinococcus multilocularis cathepsin l cysteine peptidase 0.069 0.2581 0.257
Loa Loa (eye worm) hypothetical protein 0.004 0.0099 0.0099
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.0027 0.0049 0.0035
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Schistosoma mansoni ran 0.0022 0.0028 0.0014
Echinococcus multilocularis c src tyrosine kinase 0.0031 0.0063 0.0049
Echinococcus multilocularis tyrosine protein kinase Srms 0.0031 0.0063 0.0049
Echinococcus granulosus baculoviral IAP repeat containing protein 0.0178 0.0625 0.0611
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0024 0.0043
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0283 0.1025 0.1862
Trypanosoma brucei Aph-1 protein, putative 0.0099 0.0323 0.0586
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0116 0.0115
Echinococcus granulosus intermediate filament protein 0.0027 0.0047 0.0033
Onchocerca volvulus Cathepsin L homolog 0.069 0.2581 1
Entamoeba histolytica protein kinase, putative 0.0018 0.0014 0.0054
Brugia malayi gamma-secretase subunit aph-1 0.0254 0.0914 0.0914
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Schistosoma mansoni tyrosine kinase 0.0031 0.0063 0.0049
Brugia malayi Cathepsin L-like precursor 0.069 0.2581 0.2581
Echinococcus granulosus acylamino acid releasing enzyme 0.0027 0.0049 0.0035
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0021 0.0024 0.0024
Schistosoma mansoni calpain-7 (C02 family) 0.0021 0.0024 0.001
Giardia lamblia Cathepsin L precursor 0.0229 0.0821 0.2184
Giardia lamblia Cathepsin B precursor 0.0229 0.0821 0.2184
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0022 0.0028 0.0051
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Mycobacterium leprae PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) 0.0027 0.0049 0.5
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0229 0.0821 0.3143
Leishmania major cathepsin L-like protease 0.069 0.2581 0.4687
Schistosoma mansoni cathepsin s 0.0053 0.0149 0.0135
Echinococcus multilocularis caspase 2 0.0095 0.031 0.0296
Giardia lamblia Cathepsin L-like protease 0.0229 0.0821 0.2184
Loa Loa (eye worm) cytokine inducible SH2-containing protein 5 0.0018 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0229 0.0821 0.2184
Loa Loa (eye worm) papain family cysteine protease containing protein 0.069 0.2581 0.2581
Brugia malayi prolyl oligopeptidase family protein 0.0116 0.0387 0.0387
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.069 0.2581 0.7028
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0229 0.0821 0.2184
Loa Loa (eye worm) MH2 domain-containing protein 0.0024 0.0036 0.0036
Echinococcus granulosus tyrosine kinase 0.0031 0.0063 0.0049
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0229 0.0821 0.3181
Loa Loa (eye worm) histone deacetylase 7A 0.0045 0.0116 0.0116
Echinococcus multilocularis cathepsin L 0.0229 0.0821 0.0808
Trypanosoma cruzi cysteine peptidase, putative 0.0884 0.3324 0.3324
Plasmodium falciparum cysteine proteinase falcipain 1 0.0283 0.1025 0.3938
Echinococcus multilocularis calpain family protein 1, d 0.004 0.0099 0.0085
Echinococcus granulosus histone deacetylase 0.0045 0.0116 0.0101
Echinococcus granulosus histone deacetylase 6 0.0045 0.0116 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Brugia malayi Cathepsin L-like precursor 0.069 0.2581 0.2581
Loa Loa (eye worm) prolyl oligopeptidase 0.0027 0.0049 0.0049
Echinococcus multilocularis survival motor neuron protein 1 0.0228 0.0818 0.0805
Schistosoma mansoni cathepsin B (C01 family) 0.0229 0.0821 0.0808
Schistosoma mansoni cpg binding protein 0.0028 0.0054 0.004
Onchocerca volvulus 0.0027 0.0047 0.0128
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0135 0.0461 0.0448
Plasmodium falciparum cysteine proteinase falcipain 2b 0.069 0.2581 1
Schistosoma mansoni smad 0.0024 0.0036 0.0022
Plasmodium vivax calpain, putative 0.0021 0.0024 0.0036
Schistosoma mansoni importin beta-1 0.0029 0.0058 0.0043
Echinococcus multilocularis Smad4 0.0024 0.0036 0.0022
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0031 0.0063 0.0242
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0283 0.1025 0.2745
Echinococcus granulosus cathepsin l cysteine peptidase 0.069 0.2581 0.257
Loa Loa (eye worm) STAT protein 0.0018 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Plasmodium falciparum serine repeat antigen 8 0.0229 0.0821 0.3143
Giardia lamblia Cathepsin B precursor 0.0972 0.366 1
Brugia malayi SH2 domain containing protein 0.0018 0.0014 0.0014
Plasmodium vivax unspecified product 0.0053 0.0149 0.0524
Entamoeba histolytica cysteine protease, putative 0.0283 0.1025 0.3972
Loa Loa (eye worm) hypothetical protein 0.0229 0.0821 0.0821
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0018 0.0014 0.0014
Trypanosoma cruzi major cysteine proteinase, putative 0.0424 0.1565 0.1564
Brugia malayi Smad1 0.0024 0.0036 0.0036
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0229 0.0821 0.3143
Echinococcus multilocularis tyrosine protein kinase shark 0.0031 0.0063 0.0049
Brugia malayi SH2 domain containing protein 0.0031 0.0063 0.0063
Echinococcus granulosus cathepsin b 0.2631 1 1
Giardia lamblia Cysteine protease 0.0229 0.0821 0.2184
Schistosoma mansoni tyrosine kinase 0.0031 0.0063 0.0049
Loa Loa (eye worm) hypothetical protein 0.0095 0.031 0.031
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0058 0.0118
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0229 0.0821 0.0821
Plasmodium falciparum serine repeat antigen 6 0.0229 0.0821 0.3143
Onchocerca volvulus 0.069 0.2581 1
Echinococcus granulosus cathepsin l1 0.0636 0.2377 0.2366
Brugia malayi Papain family cysteine protease containing protein 0.0283 0.1025 0.1025
Trypanosoma cruzi oligopeptidase b 0.0027 0.0049 0.0049
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0031 0.0063 0.0049
Brugia malayi SH2 domain containing protein 0.0031 0.0063 0.0063
Loa Loa (eye worm) SH2 domain-containing protein 0.0018 0.0014 0.0014
Trypanosoma brucei prolyl oligopeptidase, putative 0.0027 0.0049 0.0089
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Brugia malayi prolyl oligopeptidase family protein 0.0344 0.1258 0.1258
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0229 0.0821 0.2184
Entamoeba histolytica prolyl oligopeptidase family protein 0.0027 0.0049 0.019
Echinococcus granulosus tyrosine protein kinase Blk 0.0031 0.0063 0.0049
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0972 0.366 1
Loa Loa (eye worm) hypothetical protein 0.0229 0.0821 0.0821
Brugia malayi SH2 domain containing protein 0.0018 0.0014 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0229 0.0821 0.0821
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Loa Loa (eye worm) cysteine protease 0.069 0.2581 0.2581
Echinococcus granulosus histone deacetylase 7 0.0045 0.0116 0.0101
Echinococcus multilocularis microtubule associated protein 2 0.0696 0.2605 0.2595
Plasmodium vivax vivapain-3 0.0283 0.1025 0.3938
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Onchocerca volvulus Cathepsin F homolog 0.069 0.2581 1
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0229 0.0821 0.0808
Echinococcus granulosus tyrosine protein kinase Lyn 0.0031 0.0063 0.0049
Trypanosoma cruzi histone deacetylase, putative 0.0045 0.0116 0.0115
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.2631 1 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.0154 0.0154
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0884 0.3324 0.6038
Loa Loa (eye worm) hypothetical protein 0.0229 0.0821 0.0821
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0229 0.0821 0.2184
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Echinococcus granulosus tyrosine protein kinase ABL1 0.0031 0.0063 0.0049
Trypanosoma brucei cysteine peptidase C (CPC) 0.0972 0.366 0.6648
Loa Loa (eye worm) ctsf protein 0.069 0.2581 0.2581
Loa Loa (eye worm) hypothetical protein 0.0636 0.2377 0.2377
Echinococcus granulosus p2X purinoceptor 4 0.0067 0.02 0.0185
Loa Loa (eye worm) hypothetical protein 0.0018 0.0014 0.0014
Echinococcus granulosus tyrosine protein kinase Fyn 0.0031 0.0063 0.0049
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0314 0.1146 0.1146
Brugia malayi STAT protein, DNA binding domain containing protein 0.0018 0.0014 0.0014
Entamoeba histolytica dipeptidyl-peptidase, putative 0.0027 0.0049 0.019
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028
Echinococcus granulosus GTP binding nuclear protein Ran 0.0022 0.0028 0.0014
Loa Loa (eye worm) RNA binding protein 0.0063 0.0186 0.0186
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0021 0.0024 0.0043
Leishmania major histone deacetylase, putative 0.0045 0.0116 0.0209
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0021 0.0024 0.0024
Loa Loa (eye worm) TK/FER protein kinase 0.0031 0.0063 0.0063
Loa Loa (eye worm) hypothetical protein 0.0636 0.2377 0.2377
Brugia malayi cathepsin Z-like cysteine proteinase 0.0229 0.0821 0.0821
Loa Loa (eye worm) hypothetical protein 0.0018 0.0015 0.0015
Giardia lamblia Hypothetical protein 0.0229 0.0821 0.2184
Loa Loa (eye worm) hypothetical protein 0.0024 0.0038 0.0038
Giardia lamblia Cathepsin L-like protease 0.0229 0.0821 0.2184
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.069 0.2581 0.7028
Loa Loa (eye worm) hypothetical protein 0.0026 0.0045 0.0045
Brugia malayi hypothetical protein 0.0228 0.0818 0.0818
Schistosoma mansoni cathepsin S (C01 family) 0.0229 0.0821 0.0808
Echinococcus multilocularis cathepsin L cysteine protease 0.069 0.2581 0.257
Onchocerca volvulus Cathepsin L homolog 0.069 0.2581 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0037 0.0036
Leishmania major C-8 sterol isomerase-like protein 0.1455 0.5505 1
Echinococcus granulosus tyrosine protein kinase shark 0.0031 0.0063 0.0049
Brugia malayi hypothetical protein 0.0018 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.069 0.2581 0.7028

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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