Detailed information for compound 877532

Basic information

Technical information
  • TDR Targets ID: 877532
  • Name: 1-(2,4-dichlorophenyl)sulfonyl-4-(2,5-dimethy lphenyl)piperazine
  • MW: 399.335 | Formula: C18H20Cl2N2O2S
  • H donors: 0 H acceptors: 2 LogP: 4.65 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccc(c(c1)Cl)S(=O)(=O)N1CCN(CC1)c1cc(C)ccc1C
  • InChi: 1S/C18H20Cl2N2O2S/c1-13-3-4-14(2)17(11-13)21-7-9-22(10-8-21)25(23,24)18-6-5-15(19)12-16(18)20/h3-6,11-12H,7-10H2,1-2H3
  • InChiKey: WZXQIJNUCWGQHT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • Oprea1_813558

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0033 0.0028
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0107 0.0421
Echinococcus granulosus survival motor neuron protein 1 0.0438 0.2887 0.3435
Brugia malayi EGF-like domain containing protein 0.0482 0.3189 0.3184
Schistosoma mansoni hypothetical protein 0.0047 0.0168 0.0159
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0025 0.0019 0.0023
Echinococcus granulosus Mastin 0.0353 0.2293 0.2728
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Echinococcus granulosus glycoprotein Antigen 5 0.0353 0.2293 0.2728
Onchocerca volvulus 0.0027 0.0033 0.0033
Echinococcus multilocularis Mastin 0.0353 0.2293 0.2728
Echinococcus multilocularis tumor protein p63 0.0667 0.4473 0.5322
Schistosoma mansoni hypothetical protein 0.0353 0.2293 0.2285
Onchocerca volvulus Arrow homolog 0.1233 0.8404 0.8404
Loa Loa (eye worm) hypothetical protein 0.0113 0.0629 0.0624
Brugia malayi EGF-like domain containing protein 0.0482 0.3189 0.3184
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.003 0.0054 0.0253
Echinococcus granulosus beta LACTamase domain containing family member 0.0079 0.039 0.0465
Echinococcus multilocularis neurogenic locus protein delta 0.0482 0.3189 0.3794
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1952 1
Brugia malayi cytoplasmic intermediate filament protein 0.0027 0.003 0.0023
Giardia lamblia PHD finger protein 15 0.0058 0.0244 0.0443
Brugia malayi chromobox protein homolog 3 0.0077 0.038 0.0373
Echinococcus multilocularis jumonji domain containing protein 0.008 0.0401 0.0477
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Brugia malayi EGF-like domain containing protein 0.0482 0.3189 0.3184
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0026 0.0026 0.0115
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Toxoplasma gondii PAN domain-containing protein 0.0053 0.0209 0.0236
Echinococcus granulosus lamin 0.005 0.0192 0.0229
Echinococcus multilocularis protein dispatched 1 0.0055 0.0228 0.0272
Echinococcus granulosus neurogenic locus notch protein 0.0482 0.3189 0.3794
Loa Loa (eye worm) hypothetical protein 0.0353 0.2293 0.2289
Onchocerca volvulus 0.0053 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Loa Loa (eye worm) hypothetical protein 0.0077 0.038 0.0375
Loa Loa (eye worm) glutaminase 2 0.0195 0.1197 0.1192
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Echinococcus multilocularis protein patched 0.0049 0.0181 0.0215
Mycobacterium ulcerans hypothetical protein 0.0113 0.0631 0.2668
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0304 0.1952 1
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0038 0.0107 0.0098
Loa Loa (eye worm) hypothetical protein 0.0353 0.2293 0.2289
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0051 0.0195 0.0185
Echinococcus multilocularis enteropeptidase 0.0353 0.2293 0.2728
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0107 0.0128
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.0328 0.0319
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1952 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1952 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.003 0.0054 0.0321
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0033 0.0128
Plasmodium falciparum phd finger protein, putative 0.0058 0.0244 0.1384
Loa Loa (eye worm) hypothetical protein 0.0049 0.0186 0.0181
Mycobacterium ulcerans beta-lactamase 0.0079 0.039 0.1607
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.0385
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.1233 0.8404 0.8404
Toxoplasma gondii hypothetical protein 0.0035 0.0084 0.0088
Brugia malayi jmjC domain containing protein 0.0189 0.1155 0.1149
Onchocerca volvulus 0.0053 0.0209 0.0209
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Mycobacterium tuberculosis Probable lipase LipE 0.0079 0.039 0.1151
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0079 0.039 0.0384
Echinococcus granulosus Niemann Pick C1 protein 0.0162 0.0967 0.115
Brugia malayi Trypsin-like protease protein 5 0.0353 0.2293 0.2287
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0208 0.0199
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.039 0.0381
Schistosoma mansoni notch 0.0482 0.3189 0.3182
Mycobacterium tuberculosis Probable hydrolase 0.0079 0.039 0.1151
Onchocerca volvulus 0.0053 0.0209 0.0209
Loa Loa (eye worm) jmjC domain-containing protein 0.0119 0.067 0.0666
Echinococcus multilocularis peregrin 0.0058 0.0244 0.029
Schistosoma mansoni laminin gamma-3 chain 0.0482 0.3189 0.3182
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0353 0.2293 0.2285
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0349 0.034
Loa Loa (eye worm) hypothetical protein 0.0035 0.0087 0.0082
Brugia malayi Cadherin domain containing protein 0.0482 0.3189 0.3184
Loa Loa (eye worm) hypothetical protein 0.0024 0.001 0.0005
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Echinococcus multilocularis tissue type plasminogen activator 0.0267 0.1694 0.2016
Plasmodium vivax hypothetical protein, conserved 0.0079 0.039 0.2255
Echinococcus multilocularis musashi 0.005 0.0192 0.0229
Echinococcus multilocularis Tolloid protein 1 0.1233 0.8404 1
Echinococcus granulosus notch 0.0482 0.3189 0.3794
Brugia malayi Kringle domain containing protein 0.0267 0.1694 0.1688
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.039 0.1892
Echinococcus multilocularis fibrillin 1 0.1233 0.8404 1
Schistosoma mansoni egf-like domain protein 0.1233 0.8404 0.8403
Echinococcus granulosus neuropeptide receptor A26 0.0331 0.214 0.2547
Echinococcus granulosus delta-like protein 1 0.0482 0.3189 0.3794
Loa Loa (eye worm) hypothetical protein 0.0438 0.2887 0.2883
Loa Loa (eye worm) notch protein 0.0482 0.3189 0.3185
Echinococcus granulosus tumor protein p63 0.0667 0.4473 0.5322
Onchocerca volvulus 0.0053 0.0209 0.0209
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0107 0.0421
Loa Loa (eye worm) RNA binding protein 0.0073 0.0349 0.0344
Mycobacterium ulcerans hypothetical protein 0.0027 0.0033 0.0028
Echinococcus granulosus PHD finger protein rhinoceros 0.0058 0.0244 0.029
Echinococcus multilocularis chromobox protein 1 0.0138 0.0801 0.0953
Echinococcus granulosus fibropellin Ia 0.0482 0.3189 0.3794
Echinococcus granulosus chromobox protein 1 0.0138 0.0801 0.0953
Mycobacterium ulcerans lipase LipD 0.0079 0.039 0.1607
Brugia malayi jmjC domain containing protein 0.007 0.0328 0.0321
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0028 0.0038 0.0045
Trichomonas vaginalis chromobox protein, putative 0.0083 0.0421 0.2049
Schistosoma mansoni notch 0.0482 0.3189 0.3182
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0267 0.1694 1
Onchocerca volvulus 0.0482 0.3189 0.3189
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0033 0.0077
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0033 0.0025
Onchocerca volvulus Putative cubilin 0.0482 0.3189 0.3189
Brugia malayi Bromodomain containing protein 0.0058 0.0244 0.0237
Onchocerca volvulus 0.0079 0.039 0.039
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1952 1
Loa Loa (eye worm) Notch2 0.0482 0.3189 0.3185
Toxoplasma gondii EGF family domain-containing protein 0.0482 0.3189 0.3786
Echinococcus multilocularis protein jagged 1 0.0482 0.3189 0.3794
Trichomonas vaginalis chromobox protein, putative 0.0138 0.0801 0.4022
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0208 0.0248
Trichomonas vaginalis glutaminase, putative 0.0195 0.1197 0.6079
Echinococcus multilocularis survival motor neuron protein 1 0.0438 0.2887 0.3435
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0353 0.2293 0.2285
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0033 0.0025
Mycobacterium tuberculosis Probable lipase LipD 0.0079 0.039 0.1151
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0209 0.0203
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Schistosoma mansoni microtubule-associated protein tau 0.0486 0.3216 0.3209
Echinococcus granulosus transmembrane protease serine 3 0.0353 0.2293 0.2728
Onchocerca volvulus 0.0482 0.3189 0.3189
Schistosoma mansoni hypothetical protein 0.0047 0.0168 0.0159
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0038 0.0028
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0033 0.007
Brugia malayi RNA recognition motif domain containing protein 0.0073 0.0349 0.0342
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0024 0.0011 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0058 0.0244 0.1384
Echinococcus granulosus laminin 0.1233 0.8404 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0208 0.0199
Schistosoma mansoni hypothetical protein 0.0482 0.3189 0.3182
Onchocerca volvulus 0.0223 0.1389 0.1389
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0033 0.0028
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1462 1 1
Trichomonas vaginalis set domain proteins, putative 0.0223 0.1389 0.7079
Echinococcus granulosus enteropeptidase 0.0353 0.2293 0.2728
Echinococcus multilocularis muscleblind protein 1 0.0155 0.0921 0.1096
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0038 0.0028
Brugia malayi EGF-like domain containing protein 0.0482 0.3189 0.3184
Loa Loa (eye worm) beta-lactamase 0.0079 0.039 0.0385
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0203
Echinococcus multilocularis neurogenic locus notch protein 0.0482 0.3189 0.3794
Schistosoma mansoni hypothetical protein 0.0058 0.0244 0.0234
Mycobacterium tuberculosis Conserved protein 0.0079 0.039 0.1151
Echinococcus granulosus lysine specific demethylase 5A 0.007 0.0328 0.039
Echinococcus multilocularis muscleblind protein 0.0155 0.0921 0.1096
Toxoplasma gondii PAN domain-containing protein 0.0053 0.0209 0.0236
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Loa Loa (eye worm) PHD-finger family protein 0.0058 0.0244 0.0239
Brugia malayi Intermediate filament tail domain containing protein 0.005 0.0192 0.0185
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.039 0.2255
Toxoplasma gondii hypothetical protein 0.0053 0.0209 0.0236
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0148 0.0873 0.26
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0079 0.039 0.0385
Onchocerca volvulus 0.0053 0.0209 0.0209
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0482 0.3189 0.3182
Echinococcus granulosus neurogenic locus notch protein 0.0482 0.3189 0.3794
Loa Loa (eye worm) hypothetical protein 0.0087 0.045 0.0445
Onchocerca volvulus 0.0482 0.3189 0.3189
Giardia lamblia High cysteine protein 0.0482 0.3189 1
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.0385
Schistosoma mansoni chromobox protein 0.0138 0.0801 0.0792
Loa Loa (eye worm) hypothetical protein 0.1233 0.8404 0.8404
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0033 0.0028
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0107 0.0128
Mycobacterium ulcerans hypothetical protein 0.0353 0.2293 1
Toxoplasma gondii microneme protein, putative 0.0053 0.0209 0.0236
Onchocerca volvulus 0.0053 0.0209 0.0209
Schistosoma mansoni transcription factor LCR-F1 0.0025 0.0019 0.0009
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0033 0.0128
Echinococcus multilocularis neuropeptide s receptor 0.0331 0.214 0.2547
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Onchocerca volvulus 0.005 0.0192 0.0192
Brugia malayi RNA binding protein 0.0073 0.0349 0.0342
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.1233 0.8404 0.8403
Onchocerca volvulus 0.0353 0.2293 0.2293
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Echinococcus granulosus tar DNA binding protein 0.0073 0.0349 0.0415
Echinococcus multilocularis notch 0.0482 0.3189 0.3794
Echinococcus granulosus neurogenic locus notch protein 4 0.0482 0.3189 0.3794
Echinococcus multilocularis protein jagged 1 0.0482 0.3189 0.3794
Brugia malayi Heterochromatin protein 1 0.0138 0.0801 0.0794
Mycobacterium tuberculosis Probable esterase LipL 0.0079 0.039 0.1151
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.038 0.1837
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1952 1
Loa Loa (eye worm) hypothetical protein 0.0353 0.2293 0.2289
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.039 0.1892
Echinococcus multilocularis PHD finger protein rhinoceros 0.0058 0.0244 0.029
Trichomonas vaginalis D-aminoacylase, putative 0.0079 0.039 0.1892
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0353 0.2293 0.2728
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0083 0.0421 0.0421
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0033 0.0128
Brugia malayi Protein kinase domain containing protein 0.0267 0.1694 0.1688
Onchocerca volvulus Slit protein homolog 0.0482 0.3189 0.3189
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0033 0.0028
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0033 0.0295
Toxoplasma gondii calcium binding egf domain-containing protein 0.1233 0.8404 1
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0353 0.2293 0.2287
Brugia malayi follicle stimulating hormone receptor 0.0165 0.0987 0.098
Loa Loa (eye worm) hypothetical protein 0.0353 0.2293 0.2289
Schistosoma mansoni hypothetical protein 0.0353 0.2293 0.2285
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0203
Trichomonas vaginalis esterase, putative 0.0079 0.039 0.1892
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.0385
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0033 0.007
Schistosoma mansoni notch 0.0482 0.3189 0.3182
Brugia malayi EGF-like domain containing protein 0.0482 0.3189 0.3184
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0033 0.0025
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0026 0.0026 0.009
Schistosoma mansoni inositol monophosphatase 0.0026 0.0026 0.0016
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0244 0.0278
Onchocerca volvulus 0.0098 0.0521 0.0521
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0038 0.0107 0.01
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.003 0.0054 0.0253
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0203
Echinococcus granulosus peregrin 0.0058 0.0244 0.029
Loa Loa (eye worm) hypothetical protein 0.0155 0.0921 0.0916
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0038 0.0107 0.0572
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Schistosoma mansoni hypothetical protein 0.0267 0.1694 0.1686
Trypanosoma brucei hypothetical protein, conserved 0.0079 0.039 0.2859
Loa Loa (eye worm) TK/ROR protein kinase 0.0267 0.1694 0.169
Brugia malayi Niemann-Pick C1 protein precursor 0.0113 0.0629 0.0623
Echinococcus granulosus jumonji domain containing protein 0.008 0.0401 0.0477
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0551 0.3208
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1952 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0102 0.0551 0.3208
Schistosoma mansoni hypothetical protein 0.0047 0.0168 0.0159
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0215 0.1339 0.7887
Echinococcus multilocularis protein jagged 2 0.0482 0.3189 0.3794
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.039 0.1892
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0035 0.0087 0.008
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0209 0.0203
Mycobacterium ulcerans esterase/lipase LipP 0.0079 0.039 0.1607
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0033 0.007
Toxoplasma gondii microneme protein MIC17B 0.0053 0.0209 0.0236
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0079 0.039 0.1151
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0024 0.0012 0.0014
Mycobacterium tuberculosis Conserved hypothetical protein 0.0113 0.0631 0.1872
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0077 0.038 0.038
Leishmania major hypothetical protein, conserved 0.0267 0.1694 1
Echinococcus multilocularis transmembrane protease serine 3 0.0353 0.2293 0.2728
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.0385
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Loa Loa (eye worm) hypothetical protein 0.0127 0.0726 0.0721
Loa Loa (eye worm) hypothetical protein 0.1233 0.8404 0.8404
Onchocerca volvulus 0.0482 0.3189 0.3189
Echinococcus granulosus protein jagged 2 0.0482 0.3189 0.3794
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0027
Schistosoma mansoni notch 0.0482 0.3189 0.3182
Onchocerca volvulus 0.0482 0.3189 0.3189
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Onchocerca volvulus Neurogenic locus notch homolog 0.0482 0.3189 0.3189
Toxoplasma gondii microneme protein MIC17C 0.0053 0.0209 0.0236
Echinococcus multilocularis glycoprotein Antigen 5 0.0353 0.2293 0.2728
Brugia malayi Muscle positioning protein 4 0.0482 0.3189 0.3184
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.005 0.0192 0.0187
Brugia malayi Calcium binding EGF domain containing protein 0.0482 0.3189 0.3184
Brugia malayi Calcium binding EGF domain containing protein 0.0482 0.3189 0.3184
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0053 0.0208 0.0203
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0049 0.0181 0.0175
Schistosoma mansoni cellular tumor antigen P53 0.0098 0.0521 0.0512
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0024 0.0011 0.0013
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0038 0.0107 0.0421
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0353 0.2293 0.2285
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Onchocerca volvulus 0.0089 0.0464 0.0464
Loa Loa (eye worm) hypothetical protein 0.0155 0.0921 0.0916
Loa Loa (eye worm) hypothetical protein 0.1233 0.8404 0.8404
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0203
Plasmodium falciparum cysteine repeat modular protein 1 0.0267 0.1694 1
Brugia malayi EGF-like domain containing protein 0.0482 0.3189 0.3184
Onchocerca volvulus 0.0353 0.2293 0.2293
Brugia malayi Muscleblind-like protein 0.0155 0.0921 0.0914
Brugia malayi beta-lactamase family protein 0.0079 0.039 0.0384
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0033 0.0028
Leishmania major mitochondrial DNA polymerase beta 0.0215 0.1339 0.7887
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0033 0.0295
Loa Loa (eye worm) hypothetical protein 0.0353 0.2293 0.2289
Loa Loa (eye worm) hypothetical protein 0.0028 0.0038 0.0033
Onchocerca volvulus Alhambra homolog 0.0058 0.0244 0.0244
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.1462 1 1
Loa Loa (eye worm) hypothetical protein 0.0087 0.045 0.0445
Echinococcus multilocularis expressed conserved protein 0.0106 0.0582 0.0692
Echinococcus granulosus expressed conserved protein 0.0106 0.0582 0.0692
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Echinococcus granulosus lamin dm0 0.005 0.0192 0.0229
Echinococcus multilocularis fat cadherin tumor suppressor 0.0482 0.3189 0.3794
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0353 0.2293 0.2728
Echinococcus multilocularis ubiquitin specific protease 41 0.0038 0.0107 0.0128
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0053 0.0209 0.0236
Loa Loa (eye worm) hypothetical protein 0.1233 0.8404 0.8404
Echinococcus granulosus protein jagged 1 0.0482 0.3189 0.3794
Schistosoma mansoni cell polarity protein 0.0482 0.3189 0.3182
Trichomonas vaginalis conserved hypothetical protein 0.0049 0.0181 0.0802
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0208 0.0248
Onchocerca volvulus 0.0053 0.0209 0.0209
Echinococcus granulosus Tolloid protein 1 0.1233 0.8404 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0353 0.2293 0.2728
Brugia malayi hypothetical protein 0.0025 0.0019 0.0012
Brugia malayi TAR-binding protein 0.0073 0.0349 0.0342
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1952 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0028 0.0038 0.0045
Echinococcus multilocularis slit 2 protein 0.0482 0.3189 0.3794
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0028 0.0038 0.0045
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0304 0.1952 1
Brugia malayi Trypsin family protein 0.0353 0.2293 0.2287
Brugia malayi hypothetical protein 0.0353 0.2293 0.2287
Brugia malayi GCC2 and GCC3 family protein 0.0482 0.3189 0.3184
Echinococcus granulosus ubiquitin specific protease 41 0.0038 0.0107 0.0128
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0107 0.0572
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Schistosoma mansoni hypothetical protein 0.0089 0.0464 0.0455
Toxoplasma gondii PHD-finger domain-containing protein 0.0058 0.0244 0.0278
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0107 0.0725
Onchocerca volvulus Huntingtin homolog 0.0087 0.045 0.045
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0027 0.0031 0.0037
Onchocerca volvulus 0.0053 0.0209 0.0209
Trichomonas vaginalis penicillin-binding protein, putative 0.0079 0.039 0.1892
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0038 0.0107 0.0456
Echinococcus granulosus microtubule associated protein 2 0.0486 0.3216 0.3826
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0148 0.0873 0.3737
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0025 0.0019 0.0023
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0038 0.0107 0.0572
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0113 0.0629 0.3157
Loa Loa (eye worm) hypothetical protein 0.005 0.0192 0.0187
Onchocerca volvulus 0.0267 0.1694 0.1694
Loa Loa (eye worm) hypothetical protein 0.0038 0.0107 0.0102
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0073 0.0349 0.0344
Echinococcus multilocularis inositol monophosphatase 1 0.0026 0.0026 0.0031
Toxoplasma gondii PAN/Apple domain-containing protein 0.0053 0.0209 0.0236
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0058 0.0244 0.0234
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0037 0.01 0.0526
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0033 0.0077
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0038 0.0107 0.0128
Loa Loa (eye worm) inositol-1 0.0026 0.0026 0.0021
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0209 0.0203
Schistosoma mansoni hypothetical protein 0.0482 0.3189 0.3182
Loa Loa (eye worm) trypsin family protein 0.0353 0.2293 0.2289
Mycobacterium leprae conserved hypothetical protein 0.0079 0.039 0.4427
Echinococcus granulosus chromobox protein 1 0.0138 0.0801 0.0953
Echinococcus multilocularis lysine specific demethylase 5A 0.007 0.0328 0.039
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0026 0.0026 0.009
Brugia malayi beta-lactamase family protein 0.0079 0.039 0.0384
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Echinococcus granulosus protein jagged 1 0.0482 0.3189 0.3794
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0053 0.0208 0.0201
Echinococcus multilocularis neurogenic locus protein delta 0.0482 0.3189 0.3794
Brugia malayi Pre-SET motif family protein 0.0028 0.0038 0.0031
Onchocerca volvulus 0.0079 0.039 0.039
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0932 0.6317 0.7516
Loa Loa (eye worm) TAR-binding protein 0.0073 0.0349 0.0344
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0079 0.039 0.1151
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0349 0.034
Brugia malayi latrophilin 2 splice variant baaae 0.0024 0.001 0.0003
Brugia malayi Calcitonin receptor-like protein seb-1 0.0035 0.0087 0.008
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0027
Loa Loa (eye worm) jmjC domain-containing protein 0.007 0.0328 0.0323
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Brugia malayi CHE-14 protein 0.0049 0.0181 0.0174
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0349 0.034
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0026 0.0026 0.0036
Brugia malayi Fibulin-1 precursor 0.1233 0.8404 0.8403
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Loa Loa (eye worm) hypothetical protein 0.0024 0.0012 0.0006
Toxoplasma gondii calcium binding egf domain-containing protein 0.1233 0.8404 1
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0209 0.0203
Echinococcus granulosus intermediate filament protein 0.005 0.0192 0.0229
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0353 0.2293 0.2285
Mycobacterium tuberculosis Conserved protein 0.0079 0.039 0.1151
Brugia malayi PHD-finger family protein 0.0058 0.0244 0.0237
Echinococcus granulosus inositol monophosphatase 1 0.0026 0.0026 0.0031
Echinococcus granulosus sterol regulatory element binding protein 0.0049 0.0181 0.0215
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.003 0.0054 0.0253
Echinococcus multilocularis neurogenic locus notch protein 4 0.0482 0.3189 0.3794
Echinococcus granulosus Niemann Pick C1 protein 0.0113 0.0629 0.0749
Schistosoma mansoni hypothetical protein 0.0482 0.3189 0.3182
Loa Loa (eye worm) hypothetical protein 0.1462 1 1
Schistosoma mansoni hypothetical protein 0.0482 0.3189 0.3182
Onchocerca volvulus 0.0079 0.039 0.039
Loa Loa (eye worm) hypothetical protein 0.0099 0.053 0.0525
Loa Loa (eye worm) PAN domain-containing protein 0.0053 0.0209 0.0203
Schistosoma mansoni hypothetical protein 0.0025 0.0019 0.0009
Loa Loa (eye worm) hypothetical protein 0.1462 1 1
Echinococcus multilocularis neural cadherin 0.0482 0.3189 0.3794
Echinococcus granulosus neurogenic locus protein delta 0.0482 0.3189 0.3794
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0127 0.0726 0.0726
Onchocerca volvulus 0.0053 0.0209 0.0209
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0053 0.0208 0.0199
Schistosoma mansoni slit 0.0482 0.3189 0.3182
Mycobacterium ulcerans glutaminase 0.0195 0.1197 0.5164
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0035 0.0087 0.0082
Echinococcus multilocularis neuropeptide receptor A26 0.0331 0.214 0.2547
Brugia malayi Delta serrate ligand family protein 0.0482 0.3189 0.3184
Echinococcus multilocularis sterol regulatory element binding protein 0.0049 0.0181 0.0215
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0027 0.003 0.0025
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0353 0.2293 0.2728
Loa Loa (eye worm) intermediate filament protein 0.005 0.0192 0.0187
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0089 0.0464 0.0457
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0203
Loa Loa (eye worm) glutaminase 0.0195 0.1197 0.1192
Brugia malayi notch-like transmembrane receptor 0.0482 0.3189 0.3184
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Schistosoma mansoni hypothetical protein 0.0482 0.3189 0.3182
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0353 0.2293 0.2285
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.038 0.1837
Trypanosoma cruzi hypothetical protein, conserved 0.0267 0.1694 1
Brugia malayi Cadherin domain containing protein 0.0482 0.3189 0.3184
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.1233 0.8404 0.8404
Trichomonas vaginalis chromobox protein, putative 0.0083 0.0421 0.2049
Schistosoma mansoni lamin 0.005 0.0192 0.0182
Schistosoma mansoni hypothetical protein 0.0482 0.3189 0.3182
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0079 0.039 0.1151
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Schistosoma mansoni survival motor neuron protein 0.0089 0.0464 0.0455
Brugia malayi beta-lactamase 0.0079 0.039 0.0384
Toxoplasma gondii ABC1 family protein 0.0079 0.039 0.0452
Loa Loa (eye worm) bone morphogenetic protein 1b 0.1233 0.8404 0.8404
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0148 0.0873 1
Echinococcus granulosus neuropeptide s receptor 0.0331 0.214 0.2547
Loa Loa (eye worm) hepatopoietin HPO2 0.0024 0.0011 0.0006
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0053 0.0208 0.0248
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0038 0.0107 0.0128
Brugia malayi Calcium binding EGF domain containing protein 0.1233 0.8404 0.8403
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0223 0.1023
Plasmodium vivax SET domain protein, putative 0.0028 0.0038 0.0161
Leishmania major hypothetical protein, conserved 0.0079 0.039 0.2255
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0482 0.3189 0.3184
Loa Loa (eye worm) hypothetical protein 0.0059 0.0257 0.0251
Schistosoma mansoni patched 1 0.0049 0.0181 0.0171
Onchocerca volvulus 0.0053 0.0209 0.0209
Schistosoma mansoni chromobox protein 0.0138 0.0801 0.0792
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0079 0.039 0.1607
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.0385
Echinococcus granulosus slit 2 protein 0.0482 0.3189 0.3794
Echinococcus granulosus neural cadherin 0.0482 0.3189 0.3794
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0079 0.039 0.0381
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0203
Onchocerca volvulus 0.0353 0.2293 0.2293
Echinococcus granulosus muscleblind protein 0.0155 0.0921 0.1096
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0189 0.1155 0.1375
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0349 0.034
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0028 0.0038 0.0028
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Schistosoma mansoni tar DNA-binding protein 0.0073 0.0349 0.034
Toxoplasma gondii microneme protein MIC4 0.0053 0.0209 0.0236
Echinococcus granulosus protein jagged 2 0.0482 0.3189 0.3794
Echinococcus multilocularis Niemann Pick C1 protein 0.0113 0.0629 0.0749
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0026 0.0026 0.0018
Schistosoma mansoni hypothetical protein 0.0047 0.0168 0.0159
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0102 0.0551 0.4068
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Toxoplasma gondii kringle domain-containing protein 0.0267 0.1694 0.2005
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0024 0.0012 0.0014
Onchocerca volvulus 0.0053 0.0209 0.0209
Trypanosoma cruzi hypothetical protein, conserved 0.0079 0.039 0.2255
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0033 0.0028
Toxoplasma gondii PAN domain-containing protein 0.0053 0.0209 0.0236
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0189 0.1155 0.1375
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0215 0.1339 0.7887
Schistosoma mansoni notch 0.0482 0.3189 0.3182
Onchocerca volvulus 0.0353 0.2293 0.2293
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0115 0.0641 0.0632
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0482 0.3189 0.3189
Onchocerca volvulus 0.111 0.7551 0.7551
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0165 0.0987 0.0982
Loa Loa (eye worm) hypothetical protein 0.0061 0.0264 0.0259
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Loa Loa (eye worm) hypothetical protein 0.0098 0.0521 0.0516
Trichomonas vaginalis chromobox protein, putative 0.0138 0.0801 0.4022
Brugia malayi EGF-like domain containing protein 0.0482 0.3189 0.3184
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0223 0.1023
Toxoplasma gondii hypothetical protein 0.0053 0.0209 0.0236
Toxoplasma gondii subtilisin SUB12 0.0053 0.0209 0.0236
Schistosoma mansoni septate junction protein 0.0482 0.3189 0.3182
Echinococcus granulosus tissue type plasminogen activator 0.0267 0.1694 0.2016
Schistosoma mansoni hypothetical protein 0.0482 0.3189 0.3182
Echinococcus multilocularis beta LACTamase domain containing family member 0.0079 0.039 0.0465
Brugia malayi Augmenter of liver regeneration 0.0024 0.0011 0.0004
Loa Loa (eye worm) heterochromatin protein 1 0.0138 0.0801 0.0796
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0053 0.0208 0.0248
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0503 0.3339 1
Brugia malayi Trypsin family protein 0.0353 0.2293 0.2287
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0353 0.2293 0.2285
Brugia malayi PAN domain containing protein 0.0053 0.0209 0.0202
Schistosoma mansoni intermediate filament proteins 0.005 0.0192 0.0182
Echinococcus multilocularis neurogenic locus notch protein 0.0482 0.3189 0.3794
Schistosoma mansoni notch 0.0482 0.3189 0.3182
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0215 0.1339 1
Onchocerca volvulus 0.0061 0.0264 0.0264
Schistosoma mansoni glutaminase 0.0195 0.1197 0.1188
Echinococcus granulosus Protein patched homolog 1 0.0049 0.0181 0.0215
Brugia malayi intermediate filament protein 0.005 0.0192 0.0185
Brugia malayi glutaminase DH11.1 0.0195 0.1197 0.119
Toxoplasma gondii PAN domain-containing protein 0.0612 0.4096 0.4867
Onchocerca volvulus Huntingtin homolog 0.0087 0.045 0.045
Onchocerca volvulus 0.1462 1 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0028 0.0038 0.0032
Echinococcus multilocularis laminin 0.1233 0.8404 1
Onchocerca volvulus 0.005 0.0192 0.0192
Onchocerca volvulus 0.0353 0.2293 0.2293
Toxoplasma gondii microneme protein MIC17A 0.0053 0.0209 0.0236
Echinococcus multilocularis fibropellin Ia 0.0482 0.3189 0.3794
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.1233 0.8404 0.8403
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0304 0.1952 1
Loa Loa (eye worm) hypothetical protein 0.0058 0.0244 0.0239
Loa Loa (eye worm) hypothetical protein 0.0053 0.0209 0.0203
Mycobacterium tuberculosis Conserved protein 0.0079 0.039 0.1151
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0026 0.0026 0.5
Loa Loa (eye worm) hypothetical protein 0.0049 0.0181 0.0175
Schistosoma mansoni inositol monophosphatase 0.0026 0.0026 0.0016
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0026 0.0026 0.009
Echinococcus multilocularis Niemann Pick C1 protein 0.0162 0.0967 0.115
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Schistosoma mansoni jumonji/arid domain-containing protein 0.007 0.0328 0.0319
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0033 0.0028
Brugia malayi hypothetical protein 0.0087 0.045 0.0443
Echinococcus multilocularis lamin dm0 0.005 0.0192 0.0229
Echinococcus multilocularis lamin 0.005 0.0192 0.0229
Toxoplasma gondii PAN domain-containing protein 0.0612 0.4096 0.4867
Echinococcus multilocularis microtubule associated protein 2 0.0486 0.3216 0.3826
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0038 0.0107 0.0098
Brugia malayi hypothetical protein 0.0438 0.2887 0.2882
Schistosoma mansoni lamin 0.005 0.0192 0.0182
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0196 0.1202 0.1197
Brugia malayi Pre-SET motif family protein 0.0196 0.1202 0.1195
Toxoplasma gondii PAN domain-containing protein 0.0053 0.0209 0.0236
Onchocerca volvulus 0.0051 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0267 0.1694 0.169
Loa Loa (eye worm) hypothetical protein 0.0027 0.0033 0.0027
Brugia malayi Trypsin family protein 0.0353 0.2293 0.2287
Echinococcus multilocularis chromobox protein 1 0.0138 0.0801 0.0953
Brugia malayi Calcium binding EGF domain containing protein 0.0482 0.3189 0.3184
Mycobacterium leprae Probable lipase LipE 0.0079 0.039 0.4427
Schistosoma mansoni jumonji domain containing protein 0.015 0.0886 0.0877
Brugia malayi Inositol-1 0.0026 0.0026 0.0019
Treponema pallidum fructose-bisphosphate aldolase 0.0304 0.1952 0.5
Giardia lamblia Fructose-bisphosphate aldolase 0.0304 0.1952 0.5986
Echinococcus multilocularis tar DNA binding protein 0.0073 0.0349 0.0415
Schistosoma mansoni cercarial elastase (S01 family) 0.0353 0.2293 0.2285
Loa Loa (eye worm) hypothetical protein 0.0079 0.039 0.0385
Mycobacterium ulcerans hypothetical protein 0.0079 0.039 0.1607
Loa Loa (eye worm) hypothetical protein 0.0482 0.3189 0.3185
Loa Loa (eye worm) hypothetical protein 0.1233 0.8404 0.8404
Brugia malayi N-terminal motif family protein 0.0127 0.0726 0.0719

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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