Detailed information for compound 972241

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 329.46 | Formula: C18H23N3OS
  • H donors: 0 H acceptors: 1 LogP: 4.85 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN1CCCC(C1)COc1nc2ccsc2n2c1ccc2
  • InChi: 1S/C18H23N3OS/c1-2-8-20-9-3-5-14(12-20)13-22-17-16-6-4-10-21(16)18-15(19-17)7-11-23-18/h4,6-7,10-11,14H,2-3,5,8-9,12-13H2,1H3
  • InChiKey: UMXQETCBUUJJNG-UHFFFAOYSA-N  


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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0178
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0066 0.1717
Plasmodium falciparum glutathione reductase 0.005 0.0119 0.0101
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0172 0.0438
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0009 0.002
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0077 0.0049
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0013 0.0033
Echinococcus granulosus thioredoxin glutathione reductase 0.005 0.0119 0.0302
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0013 0.0033
Onchocerca volvulus 0.0012 0.0013 0.0067
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0066 0.0167
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0901
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0018 0.0029 0.0074
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0042 0.0098 0.025
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0166 0.0423
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi Calcitonin receptor-like protein seb-1 0.0056 0.0137 0.2137
Onchocerca volvulus 0.0046 0.0108 0.1374
Loa Loa (eye worm) hypothetical protein 0.0035 0.0076 0.1178
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Echinococcus granulosus CD36 class B scavenger receptor 0.0115 0.0302 0.077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0013 0.0033
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0076 0.0193
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0028 0.0069
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0013 0.0033
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi AKH receptor 0.0012 0.0013 0.0201
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0066 0.1022
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0018 0.0008
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0041 0.0104
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0114 0.0297 0.0405
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0013 0.0033
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0126 0.0333 0.0456
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.018
Plasmodium falciparum thioredoxin reductase 0.005 0.0119 0.0101
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0041 0.0104
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0041 0.0104
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0033
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0172 0.0155
Echinococcus granulosus lamin 0.0025 0.005 0.0125
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0039 0.0087 0.1356
Schistosoma mansoni coup transcription factor 0.0022 0.0041 0.0104
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0012 0.018
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0013 0.0201
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0031 0.0066 0.0049
Toxoplasma gondii thioredoxin reductase 0.005 0.0119 0.0101
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi hypothetical protein 0.0114 0.0298 0.4643
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0018 0.0008
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0042 0.0098 0.1527
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0109 0.3253
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0039 0.0532
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0013 0.0067
Echinococcus granulosus geminin 0.0332 0.0909 0.232
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.03 0.4674
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0013 0.0033
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0066 0.1717
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0041 0.0104
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.1186
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0031 0.0066 0.0076
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0033
Schistosoma mansoni survival motor neuron protein 0.0045 0.0105 0.0266
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0013 0.0033
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0066 0.1717
Onchocerca volvulus 0.0012 0.0013 0.0067
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0013 0.0015 0.0224
Brugia malayi nuclear receptor NHR-67 0.001 0.0009 0.0125
Brugia malayi nuclear receptor RXR 0.001 0.0009 0.0125
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0013 0.0033
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0028 0.0359
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0013 0.0033
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0041 0.0635
Schistosoma mansoni histamine h1 receptor 0.0012 0.0013 0.0033
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0098 0.025
Schistosoma mansoni cd36 antigen 0.0044 0.0101 0.0257
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0028 0.0359
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0039 0.0098
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0021 0.0039 0.0759
Echinococcus multilocularis geminin 0.0332 0.0909 0.232
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0266
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0009 0.002
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Schistosoma mansoni nuclear receptor 0.001 0.0009 0.002
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0013 0.0033
Loa Loa (eye worm) oxidoreductase 0.0014 0.0018 0.0266
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0076 0.0193
Schistosoma mansoni hypothetical protein 0.0045 0.0105 0.0266
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.03 0.4096
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0074
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0018 0.0029 0.045
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0012 0.0013 0.0032
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0013 0.0033
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0041 0.0635
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Mycobacterium ulcerans 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.3579 1 1
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0635
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0009 0.002
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0028 0.0359
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0013 0.0033
Echinococcus granulosus 6 phosphofructokinase 0.0114 0.03 0.0765
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0071 0.0084
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus granulosus neuropeptide receptor 0.0012 0.0013 0.0033
Schistosoma mansoni adenoreceptor 0.0012 0.0013 0.0033
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0046 0.0109 0.0092
Schistosoma mansoni intermediate filament proteins 0.0025 0.005 0.0125
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0041 0.0104
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0013 0.0201
Brugia malayi 6-phosphofructokinase 0.0114 0.03 0.4674
Plasmodium vivax SET domain protein, putative 0.0035 0.0076 0.0059
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0098 0.025
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0013 0.0201
Trypanosoma brucei trypanothione reductase 0.005 0.0119 0.3586
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0013 0.0033
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0028 0.001
Echinococcus multilocularis CD36 class B scavenger receptor 0.0115 0.0302 0.077
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0109 0.3253
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0012 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) RNA binding protein 0.0067 0.0166 0.2586
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0042 0.0098 0.025
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0013 0.0033
Echinococcus granulosus lysosome membrane protein 2 0.0115 0.0302 0.077
Echinococcus granulosus CD36 class B scavenger receptor 0.0115 0.0302 0.077
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0009 0.002
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0039 0.0021
Brugia malayi sulfakinin receptor protein 0.0012 0.0013 0.0201
Leishmania major trypanothione reductase 0.005 0.0119 0.3586
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0013 0.0033
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0005 0.0013
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0041 0.0104
Brugia malayi MH2 domain containing protein 0.0111 0.029 0.4516
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Echinococcus multilocularis CD36 class B scavenger receptor 0.0115 0.0302 0.077
Schistosoma mansoni lamin 0.0025 0.005 0.0125
Echinococcus multilocularis muscleblind protein 1 0.0154 0.041 0.1046
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0066 0.0049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0041 0.0635
Brugia malayi CXXC zinc finger family protein 0.0033 0.007 0.1091
Echinococcus multilocularis survival motor neuron protein 1 0.022 0.0594 0.1517
Plasmodium vivax 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.3579 1 1
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0076 0.0059
Echinococcus granulosus neuropeptide receptor 0.0012 0.0013 0.0033
Echinococcus granulosus lamin dm0 0.0025 0.005 0.0125
Brugia malayi hypothetical protein 0.0012 0.0012 0.018
Schistosoma mansoni CD36-like class B scavenger receptor 0.0115 0.0302 0.077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Loa Loa (eye worm) 6-phosphofructokinase 0.0114 0.03 0.4674
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0028 0.0359
Onchocerca volvulus 0.0012 0.0013 0.0067
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0005 0.0013
Brugia malayi cytoplasmic intermediate filament protein 0.0013 0.0017 0.0256
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0013 0.0033
Onchocerca volvulus 0.0012 0.0013 0.0067
Onchocerca volvulus 0.0012 0.0013 0.0067
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0009 0.0125
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0041 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0041 0.0635
Echinococcus granulosus cpg binding protein 0.0034 0.0076 0.0192
Loa Loa (eye worm) phosphofructokinase 0.0114 0.03 0.4674
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0028 0.0359
Schistosoma mansoni opsin-like receptor 0.0012 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0074
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0013 0.0015 0.0224
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0076 0.0193
Leishmania major ATP-dependent phosphofructokinase 0.0114 0.03 1
Brugia malayi nuclear hormone receptor 0.0022 0.0041 0.0635
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0018 0.0043
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0028 0.001
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0018 0.0266
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0013 0.0017 0.0256
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Echinococcus granulosus g protein coupled receptor 0.0012 0.0013 0.0033
Onchocerca volvulus 0.0046 0.0109 0.1394
Onchocerca volvulus 0.0012 0.0013 0.0067
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0011 0.0164
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0013 0.0033
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Brugia malayi phosphofructokinase 0.0114 0.03 0.4674
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0028 0.0359
Brugia malayi nuclear receptor NHR-88 0.0022 0.0041 0.0635
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Echinococcus multilocularis microtubule associated protein 2 0.1406 0.3916 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0013 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0046 0.0109 0.0138
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0009 0.0125
Echinococcus multilocularis lamin dm0 0.0025 0.005 0.0125
Onchocerca volvulus 0.0014 0.0018 0.0124
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus granulosus microtubule associated protein 2 0.1406 0.3916 1
Echinococcus granulosus g protein coupled receptor 0.0012 0.0013 0.0033
Loa Loa (eye worm) thioredoxin reductase 0.005 0.0119 0.1846
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0041 0.0104
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0041 0.0635
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0018 0.024
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0028 0.0022
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0013 0.0033
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0013 0.0033
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0028 0.0359
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0013 0.0201
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0041 0.0635
Loa Loa (eye worm) CXXC zinc finger family protein 0.0033 0.007 0.1091
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0041 0.0635
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0039 0.0759
Loa Loa (eye worm) DR-78 0.001 0.0009 0.0125
Schistosoma mansoni biogenic amine receptor 0.0012 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0074
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0041 0.0104
Brugia malayi neuropeptide F receptor 0.0012 0.0013 0.0201
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0066 0.1717
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0041 0.0104
Entamoeba histolytica acyl-coA synthetase, putative 0.0046 0.0109 0.3253
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0013 0.0033
Brugia malayi hypothetical protein 0.0044 0.0101 0.1572
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Schistosoma mansoni neuropeptide receptor 0.0012 0.0013 0.0033
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0041 0.0104
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0013 0.0033
Brugia malayi hypothetical protein 0.001 0.0009 0.0125
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Echinococcus multilocularis muscleblind protein 0.0154 0.041 0.1046
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0635
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0033
Echinococcus multilocularis neuropeptide receptor A26 0.0439 0.121 0.3088
Echinococcus granulosus hypothetical protein 0.0012 0.0013 0.0033
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0066 0.0049
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.005 0.0119 0.0152
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Onchocerca volvulus 0.0014 0.0018 0.0124
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.1186
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0172 0.0155
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0193
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0013 0.0033
Schistosoma mansoni biogenic amine receptor 0.0012 0.0013 0.0033
Brugia malayi nuclear hormone receptor 0.001 0.0009 0.0125
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0009 0.0125
Onchocerca volvulus 0.0269 0.0732 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0066 0.0049
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0031 0.0066 0.1715
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0018 0.0266
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0013 0.0033
Brugia malayi Thioredoxin reductase 0.005 0.0119 0.1846
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0018 0.0008
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0114 0.0297 0.028
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.03 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0012 0.0013 0.0032
Schistosoma mansoni cellular tumor antigen P53 0.0046 0.0108 0.0274
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Toxoplasma gondii 6-phosphofructokinase 0.0031 0.0066 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0066 0.0038
Brugia malayi hypothetical protein 0.0012 0.0012 0.018
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0901
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.1186
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.03 0.0765
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0635
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0012 0.0012 0.0029
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0018 0.0008
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0013 0.0033
Leishmania major 4-coumarate:coa ligase-like protein 0.0046 0.0109 0.3253
Loa Loa (eye worm) hypothetical protein 0.0115 0.0302 0.4707
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0066 0.0049
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.17
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0009 0.002
Brugia malayi glutathione reductase 0.005 0.0119 0.1846
Onchocerca volvulus 0.0012 0.0013 0.0067
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0041 0.0635
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0018 0.0008
Schistosoma mansoni CD36-like class B scavenger receptor 0.0115 0.0302 0.077
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0018 0.0029 0.0074
Brugia malayi Dopamine receptor protein 2 0.0012 0.0013 0.0201
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0018 0.0008
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0901
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0041 0.0104
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0041 0.0635
Onchocerca volvulus 0.0022 0.0041 0.0451
Mycobacterium tuberculosis Probable reductase 0.0114 0.0297 0.0405
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0018 0.0029 0.0074
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0028 0.0359
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Onchocerca volvulus Lysosome membrane protein 2 homolog 0.0115 0.0302 0.4056
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0018 0.0266
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0041 0.0104
Schistosoma mansoni neuropeptide receptor 0.0012 0.0013 0.0033
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0031 0.0066 0.0038
Echinococcus granulosus muscleblind protein 0.0154 0.041 0.1046
Echinococcus multilocularis CD36 class B scavenger receptor 0.0115 0.0302 0.077
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0166 0.0423
Brugia malayi Latrophilin receptor protein 2 0.0018 0.0029 0.045
Brugia malayi nuclear receptor NHR-88 0.001 0.0009 0.0125
Brugia malayi Serotonin receptor 0.0012 0.0013 0.0201
Onchocerca volvulus 0.0025 0.005 0.0566
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.03 0.4096
Schistosoma mansoni cpg binding protein 0.0033 0.007 0.0179
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0166 0.0423
Loa Loa (eye worm) hypothetical protein 0.0154 0.041 0.6395
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0013 0.0033
Loa Loa (eye worm) transcription factor SMAD2 0.0111 0.029 0.4516
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0009 0.002
Toxoplasma gondii histone lysine methyltransferase SET1 0.0063 0.0155 0.0138
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0028 0.0359
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0066 0.1717
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.018
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0028 0.001
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0041 0.0104
Toxoplasma gondii phosphofructokinase PFKII 0.0031 0.0066 0.0049
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0018 0.024
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0033
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0028 0.0424
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0042 0.0098 0.025
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0018 0.0043
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0901
Brugia malayi Nuclear hormone receptor E75 0.001 0.0009 0.0125
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0041 0.0451
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0109 0.3253
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0077 0.0059
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0028 0.0359
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0013 0.0201
Schistosoma mansoni zinc finger protein 0.001 0.0009 0.002
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0041 0.0104
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0013 0.0033
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0013 0.0033
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0039 0.0532
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0066 0.0167
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.1186
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0028 0.0359
Brugia malayi ecdysteroid receptor 0.0022 0.0041 0.0635
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0033
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0013 0.0033
Brugia malayi steroid hormone receptor 0.0022 0.0041 0.0635
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0046 0.0109 0.0092
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0012 0.0012 0.0029
Entamoeba histolytica acyl-CoA synthetase, putative 0.0046 0.0109 0.3253
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0011 0.0027
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Onchocerca volvulus 0.0012 0.0013 0.0067
Echinococcus granulosus survival motor neuron protein 1 0.022 0.0594 0.1517
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0028 0.0069
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0028 0.0378
Brugia malayi TAR-binding protein 0.0067 0.0166 0.2586
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0066 0.0049
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0041 0.0451
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0013 0.0033
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0045 0.0105 0.1628
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0635
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0013 0.0033
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0042 0.0098 0.025
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0013 0.0033
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0041 0.0635
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0028 0.001
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0013 0.0201
Brugia malayi RNA binding protein 0.0067 0.0166 0.2586
Brugia malayi Dopamine receptor 0.0012 0.0013 0.0201
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0028 0.0069
Onchocerca volvulus Huntingtin homolog 0.0114 0.0298 0.3999
Schistosoma mansoni hypothetical protein 0.0039 0.0087 0.0222
Brugia malayi Pre-SET motif family protein 0.0236 0.0641 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0018 0.0043
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0012 0.0012 0.0029
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0109 0.0092
Brugia malayi intermediate filament protein 0.0025 0.005 0.0765
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0109 0.0092
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0013 0.0033
Brugia malayi G-protein coupled receptor 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0041 0.0635
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0013 0.0033
Echinococcus multilocularis GPCR, family 2 0.0018 0.0029 0.0074
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0041 0.0104
Schistosoma mansoni hypothetical protein 0.0018 0.0029 0.0074
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0013 0.0201
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0009 0.002
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0018 0.0029 0.0074
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0114 0.03 0.0409
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0028 0.0359
Brugia malayi neuropeptide F receptor 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0198
Onchocerca volvulus 0.0012 0.0013 0.0067
Echinococcus multilocularis tumor protein p63 0.0314 0.0858 0.219
Schistosoma mansoni myosin xvIII 0.0012 0.0013 0.0033
Brugia malayi tailless protein 0.001 0.0009 0.0125
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0069 0.0172 0.0227
Loa Loa (eye worm) hypothetical protein 0.0025 0.0048 0.0744
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0031 0.0066 1
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0041 0.0104
Brugia malayi hypothetical protein 0.001 0.0009 0.0125
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0039 0.06
Onchocerca volvulus 0.0033 0.007 0.0855
Echinococcus granulosus serotonin receptor 0.0012 0.0013 0.0033
Schistosoma mansoni ap endonuclease 0.0021 0.0039 0.0098
Plasmodium vivax thioredoxin reductase, putative 0.005 0.0119 0.0101
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0042 0.0098 0.025
Plasmodium falciparum glutathione reductase 0.0017 0.0028 0.001
Brugia malayi GnHR receptor homolog 0.0012 0.0013 0.0201
Schistosoma mansoni nuclear receptor 0.001 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.0178
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.03 0.4096
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Mycobacterium leprae PROBABLE 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE DXR (DXP REDUCTOISOMERASE) (1-DEOXYXYLULOSE-5-PHOSPHATE REDUCTOISOMERAS 0.3579 1 1
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0011 0.0027
Loa Loa (eye worm) latrophilin receptor protein 2 0.0018 0.0029 0.045
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0013 0.0201
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0013 0.0033
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0041 0.0635
Schistosoma mansoni scavenger receptor class B type-2 (sr-B2) 0.0115 0.0302 0.077
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus granulosus fmrfamide receptor 0.0012 0.0013 0.0033
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0066 0.0167
Onchocerca volvulus 0.0035 0.0076 0.0932
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0005 0.0013
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0009 0.0125
Mycobacterium tuberculosis Probable 1-deoxy-D-xylulose 5-phosphate reductoisomerase Dxr (DXP reductoisomerase) (1-deoxyxylulose-5-phosphate reductoisomeras 0.2524 0.7047 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0013 0.0033
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0041 0.0104
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0236 0.0641 1
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi larval opioid receptor 0.0012 0.0013 0.0201
Schistosoma mansoni biogenic amine receptor 0.0012 0.0013 0.0033
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0077 0.0059
Loa Loa (eye worm) hypothetical protein 0.0056 0.0137 0.2137
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0018 0.0266
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0042 0.0098 0.1527
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Plasmodium vivax 6-phosphofructokinase, putative 0.0031 0.0066 0.0049
Echinococcus granulosus intermediate filament protein 0.0025 0.005 0.0125
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis 6 phosphofructokinase 0.0114 0.03 0.0765
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0126 0.0333 0.0456
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0066 0.0049
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0009 0.002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0077 0.1186
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis CD36 class B scavenger receptor 0.0115 0.0302 0.077
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0009 0.002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0041 0.0635
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.17
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0018 0.0266
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0041 0.0104
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0066 0.1022
Mycobacterium ulcerans hypothetical protein 0.0046 0.0109 0.0092
Onchocerca volvulus 0.0045 0.0105 0.133
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0013 0.0033
Mycobacterium ulcerans aldehyde dehydrogenase 0.0069 0.0172 0.0155
Onchocerca volvulus 0.0025 0.005 0.0566
Brugia malayi hypothetical protein 0.0044 0.0101 0.1572
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Schistosoma mansoni nuclear hormone receptor 0.001 0.0009 0.002
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0126 0.0333 0.0316
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0076 0.0193
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0031 0.0066 0.0049
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0041 0.0104
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0166 0.2586
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0041 0.0635
Echinococcus multilocularis thioredoxin glutathione reductase 0.005 0.0119 0.0302
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0021 0.0039 0.0021
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0069 0.0172 0.5465
Loa Loa (eye worm) hypothetical protein 0.0154 0.041 0.6395
Echinococcus granulosus neuropeptide receptor A26 0.0439 0.121 0.3088
Schistosoma mansoni microtubule-associated protein tau 0.1406 0.3916 1
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0114 0.0297 0.0405
Schistosoma mansoni opsin-like receptor 0.0012 0.0013 0.0033
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.03 1
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0018 0.0266
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0046 0.0109 0.0092
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0013 0.0033
Trichomonas vaginalis phosphofructokinase, putative 0.0114 0.03 0.4096
Schistosoma mansoni nuclear hormone receptor 0.001 0.0009 0.002
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Brugia malayi Dopamine receptor protein 1 0.0012 0.0013 0.0201
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0028 0.0359
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0635
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0028 0.001
Schistosoma mansoni hypothetical protein 0.0463 0.1276 0.3258
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0071 0.0084
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0635
Schistosoma mansoni cpg binding protein 0.0034 0.0076 0.0192
Loa Loa (eye worm) hypothetical protein 0.0044 0.0101 0.1572
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0901
Loa Loa (eye worm) intermediate filament protein 0.0025 0.005 0.0765
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0028 0.0359
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Schistosoma mansoni 6-phosphofructokinase 0.0114 0.03 0.0765
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0013 0.0201
Treponema pallidum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.3579 1 1
Loa Loa (eye worm) hypothetical protein 0.0115 0.0302 0.4707
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0039 0.06
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0166 0.0423
Schistosoma mansoni mixed-lineage leukemia protein mll 0.007 0.0176 0.0448
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0013 0.0033
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0041 0.0635
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0041 0.0104
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0013 0.0033
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0021 0.0039 0.2952
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0041 0.0635
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0069 0.0172 0.0438
Echinococcus granulosus neuropeptide s receptor 0.0439 0.121 0.3088
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0005 0.0013
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0013 0.0033
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0031 0.0066 0.0038
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0013 0.0033
Echinococcus granulosus dnaJ subfamily B 0.0463 0.1276 0.3258
Onchocerca volvulus 0.0012 0.0013 0.0067
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0018 0.0266
Brugia malayi Nuclear hormone receptor E75 0.001 0.0009 0.0125
Echinococcus multilocularis lysosome membrane protein 2 0.0115 0.0302 0.077
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0066 0.0167
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0039 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0029 0.045
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0041 0.0104
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0041 0.0635
Brugia malayi G protein-coupled receptor 0.0012 0.0013 0.0201
Toxoplasma gondii exonuclease III APE 0.0021 0.0039 0.0021
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0013 0.0201
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.005 0.0765
Schistosoma mansoni lamin 0.0025 0.005 0.0125
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0013 0.0033
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0013 0.0033
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0013 0.0033
Onchocerca volvulus 0.0012 0.0013 0.0067
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0013 0.0033
Echinococcus multilocularis somatostatin receptor 0.0012 0.0013 0.0033
Brugia malayi Nuclear hormone receptor-like 1 0.0012 0.0012 0.018
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0193
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0025 0.005 0.0765
Schistosoma mansoni cpg binding protein 0.0034 0.0076 0.0192
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0013 0.0033
Brugia malayi putative neuropeptide receptor 0.0012 0.0013 0.0201
Onchocerca volvulus 0.0018 0.003 0.0294
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0012 0.0012 0.018
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0039 0.0759
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0013 0.0033
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Echinococcus granulosus sex peptide receptor 0.0012 0.0013 0.0033
Echinococcus granulosus GPCR family 2 0.0018 0.0029 0.0074
Brugia malayi 6-phosphofructokinase 0.0114 0.03 0.4674
Schistosoma mansoni aldehyde dehydrogenase 0.0069 0.0172 0.0438
Mycobacterium ulcerans 6-phosphofructokinase 0.0114 0.03 0.0283
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0114 0.03 1
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0009 0.002
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0166 0.0423
Onchocerca volvulus 0.0012 0.0013 0.0067
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0077 0.0059
Brugia malayi nuclear receptor RXR 0.0012 0.0012 0.018
Onchocerca volvulus 0.0012 0.0013 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0041 0.0635
Echinococcus multilocularis serotonin receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis CD36 class B scavenger receptor 0.0115 0.0302 0.077
Loa Loa (eye worm) hypothetical protein 0.022 0.0594 0.9269
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0028 0.0359
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0013 0.0033
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0028 0.001
Echinococcus granulosus somatostatin receptor 0.0012 0.0013 0.0033
Onchocerca volvulus 0.0012 0.0013 0.0067
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0013 0.0201
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0028 0.0359
Brugia malayi Muscleblind-like protein 0.0154 0.041 0.6395
Brugia malayi RE15519p 0.0012 0.0013 0.0201
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0028 0.001
Schistosoma mansoni opsin-like receptor 0.0012 0.0013 0.0033
Brugia malayi ecdysone receptor 0.001 0.0009 0.0125
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0166 0.0423
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0041 0.0104
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0041 0.0104
Echinococcus granulosus CD36 class B scavenger receptor 0.0115 0.0302 0.077
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0056 0.0137 0.2137
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis cpg binding protein 0.0034 0.0076 0.0192
Toxoplasma gondii 1-deoxy-D-xylulose 5-phosphate reductoisomerase, putative 0.3579 1 1
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0018 0.0008
Schistosoma mansoni neuropeptide receptor 0.0012 0.0013 0.0033
Wolbachia endosymbiont of Brugia malayi 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.3579 1 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0041 0.0104
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0041 0.0635
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0013 0.0033
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0009 0.002
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0013 0.0033
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0041 0.0104
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0014 0.0018 0.0266
Loa Loa (eye worm) MH2 domain-containing protein 0.0111 0.029 0.4516
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0041 0.0104
Echinococcus granulosus CD36 class B scavenger receptor 0.0115 0.0302 0.077
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0041 0.0635
Onchocerca volvulus 0.0012 0.0013 0.0067
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0039 0.0098
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0109 0.17
Echinococcus granulosus tumor protein p63 0.0314 0.0858 0.219
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Schistosoma mansoni amine GPCR 0.0012 0.0013 0.0033
Schistosoma mansoni hypothetical protein 0.0332 0.0909 0.232
Toxoplasma gondii aldehyde dehydrogenase 0.0069 0.0172 0.0155
Echinococcus multilocularis musashi 0.0025 0.005 0.0125
Onchocerca volvulus 0.0014 0.0018 0.0124
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0114 0.03 0.0283
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.005 0.0765
Brugia malayi hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis lamin 0.0025 0.005 0.0125
Trichomonas vaginalis set domain proteins, putative 0.0269 0.0732 1
Mycobacterium tuberculosis Probable dehydrogenase 0.0114 0.0297 0.0405
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0013 0.0033
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0028 0.001
Brugia malayi follicle stimulating hormone receptor 0.0012 0.0013 0.0201
Brugia malayi ORL1-like opioid receptor 0.0012 0.0013 0.0201
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0046 0.0109 0.0092
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0013 0.0033
Echinococcus granulosus allatostatin A receptor 0.0012 0.0013 0.0033
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0009 0.002
Brugia malayi Melatonin receptor type 1A 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis neuropeptide s receptor 0.0439 0.121 0.3088
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.018
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0009 0.0125
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0076 0.0193
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0005 0.0013
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0071 0.0179
Schistosoma mansoni hypothetical protein 0.0012 0.0013 0.0033
Loa Loa (eye worm) glutathione reductase 0.005 0.0119 0.1846
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Onchocerca volvulus 0.0012 0.0013 0.0067
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0077 0.0091
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0041 0.0635
Brugia malayi Pre-SET motif family protein 0.0035 0.0076 0.1178
Schistosoma mansoni ap endonuclease 0.0021 0.0039 0.0098
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0046 0.0109 0.0092
Loa Loa (eye worm) hypothetical protein 0.0114 0.0298 0.4643
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0018 0.0008
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0028 0.001
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0039 0.0759
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Echinococcus granulosus CD36 class B scavenger receptor 0.0115 0.0302 0.077
Brugia malayi hypothetical protein 0.022 0.0594 0.9269
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0013 0.0033
Brugia malayi isocitrate dehydrogenase 0.0031 0.0066 0.1022
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0013 0.0033
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0028 0.0359
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0009 0.002
Brugia malayi G-protein coupled receptor 0.0012 0.0013 0.0201
Echinococcus granulosus orexin receptor type 2 0.0012 0.0013 0.0033
Echinococcus granulosus g protein coupled receptor 0.0012 0.0013 0.0033
Mycobacterium tuberculosis Probable oxidoreductase 0.0126 0.0333 0.0456
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.03 1
Brugia malayi latrophilin 2 splice variant baaae 0.0039 0.0087 0.1356
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0039 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0635
Echinococcus granulosus tar DNA binding protein 0.0067 0.0166 0.0423
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0041 0.0635
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0166 0.2586
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Trichomonas vaginalis phosphofructokinase, putative 0.0031 0.0066 0.0901
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0109 0.0092
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0018 0.0008
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0013 0.0201
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0114 0.0297 0.0405
Loa Loa (eye worm) hypothetical protein 0.0046 0.0108 0.1677
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0918 0.255 0.6511
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0041 0.0451
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0066 0.0167
Brugia malayi conserved hypotetical protein 0.001 0.0009 0.0125
Loa Loa (eye worm) hypothetical protein 0.0114 0.0298 0.4643
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0041 0.0104
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0041 0.0104
Onchocerca volvulus Huntingtin homolog 0.0114 0.0298 0.3999
Entamoeba histolytica phosphofructokinase, putative 0.0114 0.03 1
Schistosoma mansoni hypothetical protein 0.0332 0.0909 0.232
Echinococcus multilocularis sex peptide receptor 0.0012 0.0013 0.0033
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0056 0.0137 0.2137
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0009 0.0125
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0041 0.0635
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.001 0.0009 0.0125
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0041 0.0104
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0166 0.2586
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.018
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0109 0.17
Brugia malayi F/Y-rich N-terminus family protein 0.0011 0.0011 0.0158
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0114 0.03 0.0273
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0069 0.0172 0.0438
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0013 0.0201
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0066 0.0167
Loa Loa (eye worm) hypothetical protein 0.0022 0.0041 0.0635
Loa Loa (eye worm) hypothetical protein 0.0044 0.0101 0.1572
Onchocerca volvulus 0.0012 0.0013 0.0067
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0013 0.0033
Loa Loa (eye worm) hypothetical protein 0.0044 0.0101 0.1572
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0046 0.0109 0.0138
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0031 0.0066 0.0901
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0071 0.0084
Brugia malayi Serotonin receptor 0.0012 0.0013 0.0201
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0013 0.0033
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0009 0.0125
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0013 0.0033
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0012 0.0013 0.0201
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0009 0.002
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0013 0.0033
Echinococcus multilocularis dnaJ subfamily B 0.0463 0.1276 0.3258
Trypanosoma cruzi trypanothione reductase, putative 0.005 0.0119 0.3586
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0013 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0033 0.0071 0.0084
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0013 0.0201
Plasmodium falciparum thioredoxin reductase 0.0017 0.0028 0.001
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0013 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0018 0.0008
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0039 0.0021
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0013 0.0033
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0066 0.0167
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0114 0.0297 0.0405
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0018 0.0266
Plasmodium falciparum 1-deoxy-D-xylulose 5-phosphate reductoisomerase 0.3579 1 1
Loa Loa (eye worm) hypothetical protein 0.0012 0.0012 0.018
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0013 0.0201
Brugia malayi AMP-binding enzyme family protein 0.0046 0.0109 0.17
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0013 0.0067
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0041 0.0635
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0028 0.0378
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0013 0.0201
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0039 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0039 0.0759
Loa Loa (eye worm) hypothetical protein 0.0012 0.0013 0.0201
Loa Loa (eye worm) hypothetical protein 0.0046 0.0109 0.17
Echinococcus multilocularis serotonin receptor 0.0012 0.0013 0.0033
Schistosoma mansoni neuropeptide receptor 0.0012 0.0013 0.0033
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0018 0.0008
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0013 0.0201
Mycobacterium ulcerans acyl-CoA synthetase 0.0046 0.0109 0.0092
Loa Loa (eye worm) hypothetical protein 0.0115 0.0302 0.4707
Brugia malayi CD36 family protein 0.0115 0.0302 0.4707
Plasmodium vivax glutathione reductase, putative 0.005 0.0119 0.0101

Activities

Activity type Activity value Assay description Source Reference
Inhibition (binding) = 0 % Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane at 10 nM ChEMBL. 19261477
Inhibition (binding) = 91 % Displacement of [3H]GR-113808 from 5HT4 receptor in guinea pig striatum membrane at 1 uM ChEMBL. 19261477

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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