Detailed information for compound 1030567

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 372.864 | Formula: C21H22ClFN2O
  • H donors: 1 H acceptors: 1 LogP: 4.3 Rotable bonds: 2
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1CCN(CC1)C1=Nc2ccccc2CC=C1c1ccc(cc1)F.Cl
  • InChi: 1S/C21H21FN2O.ClH/c22-17-8-5-15(6-9-17)19-10-7-16-3-1-2-4-20(16)23-21(19)24-13-11-18(25)12-14-24;/h1-6,8-10,18,25H,7,11-14H2;1H
  • InChiKey: AJXWWTMRDZWUBA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0033 0.0123 0.0739
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0183 0.0977 0.178
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0219 0.1187 0.1187
Loa Loa (eye worm) hypothetical protein 0.0259 0.1411 0.269
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.024 0.024
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0019 0.0045 0.0031
Schistosoma mansoni glucose transport protein 0.0211 0.1137 0.2852
Schistosoma mansoni chromosome transmission fidelity factor 0.0021 0.0052 0.013
Schistosoma mansoni hypothetical protein 0.0085 0.0421 0.1056
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.007 0.0335 0.0549
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0299 0.0751
Loa Loa (eye worm) hypothetical protein 0.0076 0.0368 0.0702
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0104 0.0195
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.007 0.0038
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Mycobacterium ulcerans adenosylmethionine-8-amino-7-oxononanoate aminotransferase 0.0494 0.2756 0.5206
Brugia malayi metabotropic glutamate receptor type 2 0.0032 0.0115 0.0218
Trypanosoma brucei glucose transporter, putative 0.0065 0.0307 0.1951
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0059 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0307 0.0584
Trypanosoma brucei protein kinase, putative 0.0053 0.024 0.1518
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0022 0.006 0.0125
Brugia malayi topoisomerase 0.0021 0.0052 0.0099
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0497 0.0497
Trypanosoma cruzi hexose transporter, putative 0.003 0.0104 0.0412
Trypanosoma cruzi extracellular receptor, putative 0.0032 0.0115 0.0484
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0019 0.0045 0.0281
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.003 0.0104 0.0167
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Plasmodium falciparum calcium-dependent protein kinase 1 0.0033 0.0123 0.0295
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0299 0.0751
Mycobacterium tuberculosis Conserved protein 0.0076 0.0368 0.091
Toxoplasma gondii ornithine aminotransferase, mitochondrial precursor, putative 0.007 0.0335 0.2028
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0059 0.0112
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0117 0.0604 0.0604
Trypanosoma cruzi glucose transporter, putative 0.003 0.0104 0.0412
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0024 0.007 0.0438
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0019 0.004 0.01
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Trichomonas vaginalis acetylornithine aminotransferase, putative 0.0494 0.2756 0.5251
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0062 0.0286 0.0286
Wolbachia endosymbiont of Brugia malayi acetylornithine transaminase protein 0.007 0.0335 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0052 0.0097
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0045 0.0031
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0059 0.0145
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0059 0.0112
Brugia malayi hypothetical protein 0.0021 0.0052 0.0099
Echinococcus multilocularis tyrosine kinase 0.0032 0.0115 0.0115
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0076 0.0368 0.0702
Echinococcus granulosus glutamate receptor subunit protein glur 0.0062 0.0286 0.0709
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0068 0.0325 0.0816
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0115 0.0218
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.024 0.0601
Trichomonas vaginalis PIKK family atypical protein kinase 0.0025 0.008 0.0151
Loa Loa (eye worm) glutamate receptor 2 0.0062 0.0286 0.0545
Echinococcus granulosus metabotropic glutamate receptor 2 0.0032 0.0115 0.0284
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.024 0.0383
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0033 0.0123 0.0304
Brugia malayi 4-aminobutyrate aminotransferase, mitochondrial precursor 0.007 0.0335 0.0639
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0307 0.1951
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0368 0.07
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Schistosoma mansoni hypothetical protein 0.0076 0.0368 0.0923
Brugia malayi Guanylyl cyclase protein 23 0.0032 0.0115 0.0218
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Plasmodium falciparum ornithine aminotransferase 0.007 0.0335 0.1159
Plasmodium falciparum protein kinase 6 0.0451 0.2511 1
Trichomonas vaginalis conserved hypothetical protein 0.0211 0.1137 0.2166
Brugia malayi Glutamate receptor 2 precursor 0.0062 0.0286 0.0545
Brugia malayi latrophilin 2 splice variant baaae 0.0177 0.0944 0.1799
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0096
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.0158 0.0838 0.2102
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0158 0.0835 0.2219
Onchocerca volvulus 0.003 0.0104 0.0099
Brugia malayi Metabotropic glutamate receptor precursor. 0.0032 0.0115 0.0218
Brugia malayi Low molecular weight phosphotyrosine protein phosphatase containing protein 0.093 0.5247 1
Echinococcus granulosus General substrate transporter 0.0181 0.0968 0.24
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0059 0.0147
Brugia malayi calpain family protein 1 0.0065 0.0306 0.0584
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0033 0.0123 0.0775
Schistosoma mansoni hypothetical protein 0.0082 0.0402 0.1008
Entamoeba histolytica hypothetical protein 0.0109 0.0554 0.0987
Schistosoma mansoni glutamate receptor kainate 0.0062 0.0286 0.0717
Onchocerca volvulus 0.0105 0.0534 0.0929
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0158 0.0835 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Trypanosoma brucei glucose transporter, putative 0.0065 0.0307 0.1951
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0059 0.0147
Echinococcus granulosus solute carrier family 22 0.003 0.0104 0.0257
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0032 0.0116 0.0222
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.1137 0.1137
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0019 0.004 0.01
Onchocerca volvulus 0.003 0.0104 0.0099
Loa Loa (eye worm) hypothetical protein 0.0022 0.0059 0.0112
Loa Loa (eye worm) hypothetical protein 0.0076 0.0368 0.0702
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0089 0.0148
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0017 0.0029 0.0073
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Schistosoma mansoni glutamate receptor NMDA 0.0093 0.0466 0.1169
Mycobacterium tuberculosis Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase) 0.0644 0.3609 1
Schistosoma mansoni glutamate receptor kainate 0.0062 0.0286 0.0717
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.024 0.13
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0089 0.0075
Trypanosoma cruzi FHA domain containing protein, putative 0.0021 0.0052 0.0076
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0123 0.0123
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0032 0.0115 0.0115
Schistosoma mansoni metabotropic glutamate receptor 0.0032 0.0115 0.0287
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0033 0.0123 0.0739
Entamoeba histolytica hypothetical protein 0.0109 0.0554 0.0987
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0059 0.0059
Schistosoma mansoni glutamate receptor AMPA 0.0062 0.0286 0.0717
Chlamydia trachomatis DNA ligase 0.0021 0.0052 0.0022
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0019 0.004 0.0251
Echinococcus multilocularis glutamate receptor 2 0.0062 0.0286 0.0286
Brugia malayi hypothetical protein 0.0032 0.0115 0.0218
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0604 0.1516
Onchocerca volvulus 0.0032 0.0115 0.012
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0123 0.0304
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.0089 0.0075
Schistosoma mansoni cellular tumor antigen P53 0.0105 0.0534 0.134
Onchocerca volvulus 0.003 0.0104 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Echinococcus granulosus protein will die slowly 0.0076 0.0368 0.0912
Loa Loa (eye worm) hypothetical protein 0.0076 0.0368 0.0702
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0089 0.0094
Echinococcus granulosus atrial natriuretic peptide receptor 0.0032 0.0115 0.0284
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0109 0.0554 0.1374
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0082 0.0402 0.0996
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0032 0.0115 0.0218
Schistosoma mansoni transcription factor LCR-F1 0.0109 0.0554 0.139
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0497 0.1246
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0096
Schistosoma mansoni calpain-7 (C02 family) 0.0023 0.0064 0.0159
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0045 0.0031
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0059 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0104 0.0195
Mycobacterium ulcerans 4-aminobutyrate aminotransferase 0.007 0.0335 0.0549
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0059 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0021 0.0052 0.0022
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0076 0.0368 0.091
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.004 0.0077
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0299 0.057
Plasmodium vivax calcium-dependent protein kinase, putative 0.0033 0.0123 0.0315
Loa Loa (eye worm) hypothetical protein 0.0012 0.0001 0.0002
Loa Loa (eye worm) beta-lactamase 0.0076 0.0368 0.0702
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0093 0.0466 0.1155
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0033 0.0123 0.0739
Toxoplasma gondii target of rapamycin (TOR), putative 0.0019 0.004 0.0239
Echinococcus granulosus nibrin 0.0021 0.0052 0.0129
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0497 0.0946
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.024 0.13
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0307 0.1951
Schistosoma mansoni protein kinase 0.0033 0.0123 0.0308
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Mycobacterium ulcerans L-lysine aminotransferase 0.007 0.0335 0.0549
Entamoeba histolytica protein tyrosine phosphatase, putative 0.093 0.5247 1
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Brugia malayi hypothetical protein 0.0019 0.0042 0.0081
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0104 0.0195
Echinococcus multilocularis tumor protein p63 0.0718 0.4034 0.4034
Schistosoma mansoni hypothetical protein 0.0082 0.0402 0.1008
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0158 0.0835 0.1511
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0299 0.057
Loa Loa (eye worm) hypothetical protein 0.0024 0.007 0.0133
Echinococcus multilocularis solute carrier family 22 0.003 0.0104 0.0104
Onchocerca volvulus 0.003 0.0104 0.0099
Mycobacterium tuberculosis Probable acetylornithine aminotransferase ArgD 0.007 0.0335 0.0818
Onchocerca volvulus 0.0046 0.0196 0.0277
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0076 0.0368 0.091
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Mycobacterium tuberculosis Probable L-lysine-epsilon aminotransferase Lat (L-lysine aminotransferase) (lysine 6-aminotransferase) 0.007 0.0335 0.0818
Echinococcus granulosus ornithine aminotransferase 0.007 0.0335 0.0832
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0146 0.0693
Toxoplasma gondii facilitative glucose transporter GT1 0.0211 0.1137 0.6889
Onchocerca volvulus 0.0076 0.0368 0.0609
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0059 0.0145
Loa Loa (eye worm) hypothetical protein 0.0076 0.0368 0.0702
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0102 0.0611
Onchocerca volvulus 0.0076 0.0368 0.0609
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0089 0.032
Echinococcus granulosus voltage dependent calcium channel subunit 0.0363 0.2006 0.4974
Mycobacterium ulcerans acetylornithine aminotransferase 0.007 0.0335 0.0549
Loa Loa (eye worm) hypothetical protein 0.0046 0.0196 0.0373
Brugia malayi Receptor family ligand binding region containing protein 0.0032 0.0115 0.0218
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Schistosoma mansoni coup transcription factor 0.0022 0.0059 0.0147
Plasmodium falciparum proline--tRNA ligase 0.0037 0.0146 0.0391
Schistosoma mansoni calpain-7 (C02 family) 0.0023 0.0064 0.0159
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0059 0.0112
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Mycobacterium tuberculosis Probable aminotransferase 0.0494 0.2756 0.7605
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.1137 0.1137
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0291 0.0721
Giardia lamblia Replication factor C, subunit 1 0.0021 0.0052 0.0022
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0172 0.0917 0.5553
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0115 0.0284
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0299 0.0751
Echinococcus multilocularis geminin 0.0377 0.2086 0.2086
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0025 0.008 0.0152
Trypanosoma brucei glucose transporter, putative 0.0065 0.0307 0.1951
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0059 0.0059
Brugia malayi steroid hormone receptor 0.0022 0.0059 0.0112
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0604 0.1516
Loa Loa (eye worm) hypothetical protein 0.0177 0.0944 0.1799
Loa Loa (eye worm) hypothetical protein 0.0032 0.0116 0.0222
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0123 0.0123
Onchocerca volvulus Putative transporter 0.003 0.0104 0.0099
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0062 0.0286 0.0286
Trypanosoma cruzi kinesin, putative 0.0019 0.0045 0.0031
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0045 0.0281
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0059 0.0145
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0045 0.0031
Plasmodium falciparum calcium-dependent protein kinase 5 0.0033 0.0123 0.0295
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0368 0.07
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0052 0.0324
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0052 0.0076
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0307 0.0584
Mycobacterium ulcerans phosphotyrosine protein phosphatase PtpA 0.093 0.5247 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0045 0.0031
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0497 0.1231
Brugia malayi beta-lactamase family protein 0.0076 0.0368 0.0702
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0093 0.0466 0.1155
Trypanosoma cruzi hypothetical protein, conserved 0.0021 0.0052 0.0076
Schistosoma mansoni dihydropyridine-sensitive l-type calcium channel 0.008 0.039 0.0978
Onchocerca volvulus 0.0076 0.0368 0.0608
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0019 0.004 0.0101
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0045 0.0031
Echinococcus granulosus family C2 unassigned peptidase C02 family 0.0068 0.0325 0.0806
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0062 0.0286 0.0709
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0033 0.0123 0.0234
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0032 0.0116 0.022
Onchocerca volvulus 0.0076 0.0368 0.0609
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0059 0.0059
Loa Loa (eye worm) calpain 0.0019 0.0045 0.0086
Leishmania major hypothetical protein, conserved 0.003 0.0104 0.0412
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0052 0.0097
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.003 0.0104 0.0217
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0604 0.1516
Loa Loa (eye worm) calpain family protein 1 0.0065 0.0306 0.0584
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0019 0.004 0.0251
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0287 0.1572 0.2995
Loa Loa (eye worm) hypothetical protein 0.0022 0.0059 0.0112
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0307 0.1744
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0307 0.0584
Toxoplasma gondii ATPase, AAA family protein 0.0021 0.0052 0.0309
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0062 0.0286 0.0709
Onchocerca volvulus 0.003 0.0104 0.0099
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0099
Plasmodium vivax hypothetical protein, conserved 0.0076 0.0368 0.1311
Echinococcus multilocularis GPCR, family 2 0.0082 0.0402 0.0402
Echinococcus multilocularis serine protein kinase ATM 0.0025 0.008 0.008
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0045 0.0281
Schistosoma mansoni DNA ligase IV 0.0021 0.0052 0.013
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0076 0.0368 0.0612
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.007 0.0175
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0099
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0102 0.0209
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0089 0.017
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.1137 0.2819
Echinococcus granulosus solute carrier family 22 0.003 0.0104 0.0257
Plasmodium falciparum calcium-dependent protein kinase 3 0.0033 0.0123 0.0295
Onchocerca volvulus 0.003 0.0104 0.0099
Leishmania major hypothetical protein, conserved 0.0287 0.1572 1
Mycobacterium ulcerans integral membrane transport protein 0.003 0.0104 0.0103
Schistosoma mansoni serine-rich repeat protein 0.0085 0.0421 0.1056
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0115 0.0218
Loa Loa (eye worm) hypothetical protein 0.0082 0.0402 0.0766
Schistosoma mansoni protein kinase 0.0033 0.0123 0.0308
Plasmodium vivax proline--tRNA ligase, putative 0.0037 0.0146 0.0411
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0104 0.0197
Schistosoma mansoni hypothetical protein 0.0082 0.0402 0.1008
Plasmodium vivax ornithine aminotransferase, putative 0.007 0.0335 0.1178
Echinococcus granulosus metabotropic glutamate receptor 5 0.0032 0.0115 0.0284
Loa Loa (eye worm) phosphatidylinositol 3 0.0019 0.004 0.0077
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0059 0.0112
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.093 0.5247 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Loa Loa (eye worm) hypothetical protein 0.0022 0.0059 0.0112
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0033 0.0123 0.0234
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0059 0.0112
Brugia malayi hypothetical protein 0.0109 0.0554 0.1056
Echinococcus granulosus Aminotransferase class III 0.007 0.0335 0.0832
Echinococcus granulosus nmda type glutamate receptor 0.0219 0.1187 0.2942
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0076 0.0368 0.0702
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Entamoeba histolytica protein tyrosine phosphatase, putative 0.093 0.5247 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Echinococcus multilocularis Sugar transporter ERD6 protein 0.003 0.0104 0.0104
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0307 0.1744
Schistosoma mansoni ATP-binding cassette transporter 0.0062 0.0286 0.0717
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Loa Loa (eye worm) hypothetical protein 0.0022 0.0059 0.0112
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0019 0.004 0.0101
Loa Loa (eye worm) hypothetical protein 0.0022 0.0059 0.0112
Schistosoma mansoni tyrosine kinase 0.0032 0.0115 0.0287
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.003 0.0104 0.0103
Echinococcus multilocularis ornithine aminotransferase 0.007 0.0335 0.0335
Trypanosoma brucei glucose transporter, putative 0.0065 0.0307 0.1951
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0165 0.0877 0.0877
Onchocerca volvulus 0.003 0.0104 0.0099
Mycobacterium ulcerans beta-lactamase 0.0076 0.0368 0.0612
Mycobacterium tuberculosis Conserved protein 0.0076 0.0368 0.091
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0059 0.0112
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0093 0.0466 0.0466
Echinococcus multilocularis hypothetical protein 0.0019 0.0045 0.0045
Brugia malayi DKFZp564C0469 protein 0.0021 0.0052 0.0099
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0032 0.0116 0.0146
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0158 0.0835 1
Toxoplasma gondii melibiase subfamily protein 0.0117 0.0604 0.3658
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Loa Loa (eye worm) MH2 domain-containing protein 0.0139 0.0727 0.1385
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0045 0.0281
Echinococcus granulosus serine protein kinase ATM 0.0025 0.008 0.0198
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0019 0.004 0.004
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0045 0.0031
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0117 0.0604 0.0604
Echinococcus granulosus calpain A 0.0068 0.0325 0.0806
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0062 0.0286 0.0709
Echinococcus multilocularis calpain A 0.0068 0.0325 0.0325
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0104 0.0197
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0082 0.0402 0.0766
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0052 0.0097
Brugia malayi Latrophilin receptor protein 2 0.0082 0.0402 0.0766
Schistosoma mansoni serine/threonine protein kinase 0.0033 0.0123 0.0308
Plasmodium vivax lysine--tRNA ligase, putative 0.0024 0.007 0.01
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.003 0.0104 0.026
Echinococcus multilocularis replication factor c subunit 1 0.0021 0.0052 0.0052
Onchocerca volvulus 0.0027 0.0089 0.0072
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0062 0.0286 0.0286
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0307 0.0584
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0021 0.0052 0.0099
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0082 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0497 0.0497
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.0089 0.0128
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.024 0.0455
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0059 0.0112
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0291 0.0463
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0045 0.0031
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0307 0.0584
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.0287 0.1572 0.2995
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0019 0.004 0.004
Loa Loa (eye worm) RGC/RGC protein kinase 0.0032 0.0115 0.0218
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0381 0.0956
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0307 0.0584
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Echinococcus granulosus synaptic vesicle 2 protein 0.003 0.0104 0.0257
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0093 0.0466 0.1155
Loa Loa (eye worm) hypothetical protein 0.0026 0.0082 0.0157
Brugia malayi lysyl-tRNA synthetase 0.0024 0.007 0.0133
Leishmania major glucose transporter, lmgt3 0.0065 0.0307 0.1744
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0307 0.0584
Brugia malayi hypothetical protein 0.0021 0.0052 0.0099
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0032 0.0116 0.0288
Loa Loa (eye worm) calpain 5 0.0019 0.0045 0.0086
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0052 0.0097
Entamoeba histolytica hypothetical protein 0.0109 0.0554 0.0987
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0059 0.0112
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0059 0.0059
Leishmania major lysyl-tRNA synthetase, putative 0.0024 0.007 0.0192
Brugia malayi hypothetical protein 0.003 0.0104 0.0197
Schistosoma mansoni glucose transport protein 0.0211 0.1137 0.2852
Echinococcus multilocularis ornithine aminotransferase 0.007 0.0335 0.0335
Entamoeba histolytica hypothetical protein 0.0032 0.0115 0.0143
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0059 0.0147
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Plasmodium falciparum lysine--tRNA ligase 0.0024 0.007 0.0079
Plasmodium falciparum hexose transporter 0.0211 0.1137 0.4418
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0059 0.0147
Echinococcus multilocularis microtubule associated protein 2 0.071 0.3987 0.3987
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0116 0.0292
Brugia malayi beta-lactamase 0.0076 0.0368 0.0702
Leishmania major kinesin, putative 0.0019 0.0045 0.0031
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0032 0.0116 0.0222
Trypanosoma cruzi hypothetical protein, conserved 0.0287 0.1572 1
Echinococcus multilocularis solute carrier family 22 0.003 0.0104 0.0104
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0093 0.0466 0.0466
Brugia malayi RNA binding protein 0.0064 0.0299 0.057
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0009 0.0009
Onchocerca volvulus 0.003 0.0104 0.0099
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0123 0.0304
Echinococcus multilocularis receptor type guanylyl cyclase 0.0032 0.0115 0.0115
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Brugia malayi hypothetical protein 0.003 0.0104 0.0197
Echinococcus multilocularis synaptic vesicle 2 protein 0.003 0.0104 0.0104
Schistosoma mansoni calpain (C02 family) 0.0019 0.0045 0.0113
Loa Loa (eye worm) hypothetical protein 0.0076 0.0368 0.0702
Plasmodium falciparum replication factor C subunit 1, putative 0.0021 0.0052 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0497 0.1246
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0078 0.0381 0.0725
Mycobacterium ulcerans esterase/lipase LipP 0.0076 0.0368 0.0612
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Echinococcus granulosus receptor type guanylyl cyclase 0.0032 0.0115 0.0284
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0021 0.0052 0.0097
Entamoeba histolytica hypothetical protein 0.0025 0.008 0.0076
Toxoplasma gondii sugar transporter ST3 0.003 0.0104 0.0622
Loa Loa (eye worm) phosphotyrosine protein phosphatase 0.093 0.5247 1
Leishmania major hypothetical protein, conserved 0.0029 0.0102 0.0401
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0368 0.2142
Echinococcus multilocularis protein will die slowly 0.0076 0.0368 0.0368
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0307 0.1744
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0102 0.0641
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0486 0.2707 0.7469
Trypanosoma brucei low molecular weight protein tyrosine phosphatase, putative 0.0287 0.1572 1
Loa Loa (eye worm) hypothetical protein 0.0065 0.0306 0.0584
Chlamydia trachomatis glutamine binding protein 0.0158 0.0835 1
Trichomonas vaginalis CAMK family protein kinase 0.0033 0.0123 0.0232
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0123 0.0123
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0059 0.0147
Loa Loa (eye worm) sugar transporter 0.003 0.0104 0.0197
Onchocerca volvulus 0.003 0.0104 0.0099
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0025 0.008 0.02
Brugia malayi MAP kinase sur-1 0.0053 0.024 0.0456
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0059 0.0112
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0021 0.0053 0.0099
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Echinococcus multilocularis nmda type glutamate receptor 0.0219 0.1187 0.1187
Trichomonas vaginalis glucose transporter, putative 0.003 0.0104 0.0195
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.024 0.0456
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.1137 0.2819
Trypanosoma cruzi hexose transporter, putative 0.0036 0.0138 0.0639
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0059 0.0059
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.024 0.0455
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0021 0.0052 0.0003
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0025 0.008 0.0503
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0172 0.0917 0.3536
Mycobacterium leprae conserved hypothetical protein 0.0076 0.0368 0.1179
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0059 0.0112
Brugia malayi hypothetical protein 0.003 0.0104 0.0197
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0059 0.0112
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0307 0.1744
Mycobacterium ulcerans hypothetical protein 0.0494 0.2756 0.5206
Echinococcus granulosus calpain 5 0.0019 0.0045 0.0112
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Brugia malayi Pax transcription activation domain interacting protein 0.0021 0.0052 0.0099
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.093 0.5247 1
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0025 0.008 0.0258
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Onchocerca volvulus 0.003 0.0104 0.0099
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0021 0.0052 0.0309
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0045 0.0031
Echinococcus multilocularis solute carrier family 22 0.003 0.0104 0.0104
Onchocerca volvulus 0.0022 0.0059 0.0013
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Echinococcus granulosus neuropeptide receptor A26 0.0528 0.2948 0.7309
Entamoeba histolytica protein kinase, putative 0.0033 0.0123 0.0158
Echinococcus granulosus beta LACTamase domain containing family member 0.0076 0.0368 0.0913
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0096
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0059 0.0145
Entamoeba histolytica hypothetical protein 0.0109 0.0554 0.0987
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Echinococcus granulosus calcium dependent protein kinase 0.0031 0.0109 0.0269
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0291 0.073
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0059 0.0059
Echinococcus multilocularis calpain family protein 1, d 0.0046 0.0196 0.0196
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.024 0.1446
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0009 0.0023
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0104 0.0197
Brugia malayi nuclear receptor NHR-88 0.0022 0.0059 0.0112
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Loa Loa (eye worm) hypothetical protein 0.0032 0.0116 0.0222
Schistosoma mansoni topbp1 0.0021 0.0052 0.013
Plasmodium falciparum protein kinase 7 0.0301 0.165 0.6503
Schistosoma mansoni Mername-AA248 (C02 family) 0.0019 0.0045 0.0113
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.0089 0.0075
Brugia malayi TAR-binding protein 0.0064 0.0299 0.057
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0059 0.0112
Brugia malayi Major Facilitator Superfamily protein 0.003 0.0104 0.0197
Schistosoma mansoni hypothetical protein 0.0082 0.0402 0.1008
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.024 0.0455
Plasmodium vivax CDK-related protein kinase 6, putative 0.0451 0.2511 1
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.093 0.5247 1
Giardia lamblia Hexose transporter 0.003 0.0104 0.0121
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0158 0.0835 1
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0045 0.0031
Schistosoma mansoni sugar transporter 0.003 0.0104 0.026
Echinococcus multilocularis neuropeptide receptor A26 0.0528 0.2948 0.2948
Onchocerca volvulus 0.093 0.5247 1
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.024 0.0455
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0033 0.0123 0.0315
Loa Loa (eye worm) calpain family protein 1 0.0046 0.0196 0.0373
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0059 0.0059
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Loa Loa (eye worm) hypothetical protein 0.0183 0.0977 0.1861
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0104 0.0195
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0062 0.0286 0.0286
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.003 0.0104 0.1819
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0059 0.0145
Mycobacterium tuberculosis Probable esterase LipL 0.0076 0.0368 0.091
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0089 0.032
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0299 0.057
Toxoplasma gondii sugar transporter ST1 0.003 0.0104 0.0622
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.003 0.0104 0.0167
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0093 0.0466 0.1155
Echinococcus multilocularis solute carrier family 22 0.003 0.0104 0.0104
Echinococcus granulosus tumor protein p63 0.0718 0.4034 1
Brugia malayi Will die slowly protein 0.0076 0.0368 0.0701
Schistosoma mansoni tyrosine kinase 0.0032 0.0115 0.0287
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0021 0.0052 0.001
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Leishmania major hypothetical protein, conserved 0.0076 0.0368 0.2142
Schistosoma mansoni hypothetical protein 0.0109 0.0554 0.139
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0059 0.0145
Trypanosoma brucei glucose transporter, putative 0.0065 0.0307 0.1951
Giardia lamblia Low molecular weight protein-tyrosine-phosphatase 0.093 0.5247 1
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Loa Loa (eye worm) hypothetical protein 0.0027 0.0089 0.017
Brugia malayi major facilitator superfamily protein 0.003 0.0104 0.0197
Schistosoma mansoni calpain C (C02 family) 0.0019 0.0045 0.0113
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0291 0.1636
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Schistosoma mansoni hypothetical protein 0.0013 0.0009 0.0024
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0032 0.0116 0.0292
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0082 0.0402 0.0402
Echinococcus granulosus Sugar transporter ERD6 protein 0.003 0.0104 0.0257
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0059 0.0147
Schistosoma mansoni protein kinase 0.0033 0.0123 0.0308
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0024 0.007 0.0038
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.024 0.1518
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0068 0.0325 0.0816
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0082 0.0402 0.0996
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0021 0.0052 0.0076
Schistosoma mansoni family C2 unassigned peptidase (C02 family) 0.0065 0.0306 0.0768
Mycobacterium ulcerans lipase LipD 0.0076 0.0368 0.0612
Brugia malayi Sugar transporter family protein 0.003 0.0104 0.0197
Schistosoma mansoni glucose transport protein 0.0211 0.1137 0.2852
Giardia lamblia Lysyl-tRNA synthetase 0.0024 0.007 0.0056
Echinococcus multilocularis calcium dependent protein kinase 0.0031 0.0109 0.0109
Brugia malayi major facilitator superfamily protein 0.003 0.0104 0.0197
Loa Loa (eye worm) hypothetical protein 0.0022 0.0059 0.0112
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0019 0.0045 0.0031
Schistosoma mansoni microtubule-associated protein tau 0.071 0.3987 1
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0368 0.07
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0059 0.0013
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0059 0.0147
Echinococcus multilocularis calpain 5 0.0019 0.0045 0.0045
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Trypanosoma cruzi hypothetical protein, conserved 0.0076 0.0368 0.2142
Echinococcus multilocularis glutamate receptor 2 0.0032 0.0115 0.0115
Brugia malayi calpain family protein 1 0.0065 0.0306 0.0584
Mycobacterium tuberculosis Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA 0.0494 0.2756 0.7605
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.024 0.024
Toxoplasma gondii lysine-tRNA ligase 0.0024 0.007 0.0417
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.1137 0.2819
Echinococcus multilocularis nibrin 0.0021 0.0052 0.0052
Echinococcus multilocularis neuropeptide s receptor 0.0528 0.2948 0.2948
Trichomonas vaginalis low molecular weight protein-tyrosine-phosphatase, putative 0.093 0.5247 1
Loa Loa (eye worm) WD40 repeat protein 0.0076 0.0368 0.0701
Plasmodium vivax sugar transporter, putative 0.003 0.0104 0.0237
Brugia malayi Cache domain containing protein 0.0073 0.0352 0.067
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.0089 0.0075
Plasmodium vivax acyl-CoA synthetase, putative 0.002 0.005 0.0021
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0146 0.0693
Brugia malayi Cam kinase protein 1 0.0033 0.0123 0.0234
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Echinococcus granulosus tar DNA binding protein 0.0064 0.0299 0.0742
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0059 0.0147
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0102 0.0401
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0059 0.0112
Brugia malayi MH2 domain containing protein 0.0139 0.0727 0.1385
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0109 0.0554 0.0554
Onchocerca volvulus 0.003 0.0104 0.0099
Trypanosoma cruzi sugar transporter, putative 0.003 0.0104 0.0412
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0102 0.0209
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0059 0.0112
Brugia malayi Glutamate receptor 1 precursor 0.0062 0.0286 0.0545
Leishmania major extracellular receptor, putative 0.0032 0.0115 0.0484
Leishmania major phosphatidylinositol kinase related protein, putative 0.0019 0.0041 0.0001
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.005 0.0018
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0146 0.0693
Loa Loa (eye worm) transcription factor SMAD2 0.0139 0.0727 0.1385
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Loa Loa (eye worm) glutamate receptor 1 0.0062 0.0286 0.0545
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Entamoeba histolytica hypothetical protein 0.0024 0.007 0.0056
Trypanosoma brucei glucose transporter, putative 0.0065 0.0307 0.1951
Echinococcus granulosus neuropeptide s receptor 0.0528 0.2948 0.7309
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0027 0.0089 0.0148
Mycobacterium tuberculosis Probable lipase LipE 0.0076 0.0368 0.091
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0089 0.0075
Trypanosoma brucei kinesin, putative 0.0019 0.0045 0.0281
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0033 0.0123 0.0234
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0211 0.1137 0.1137
Toxoplasma gondii protein kinase, putative 0.0301 0.165 1
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0102 0.0401
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0059 0.0112
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0497 0.1246
Onchocerca volvulus 0.003 0.0104 0.0099
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0099
Onchocerca volvulus 0.003 0.0104 0.0099
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.0089 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0102 0.0194
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0059 0.0145
Schistosoma mansoni topbp1 0.0021 0.0052 0.013
Brugia malayi Sugar transporter family protein 0.0211 0.1137 0.2167
Brugia malayi N-terminal motif family protein 0.0183 0.0977 0.1861
Loa Loa (eye worm) hypothetical protein 0.0022 0.0059 0.0112
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.093 0.5247 1
Echinococcus granulosus calpain 7 C02 family 0.0019 0.0045 0.0112
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.003 0.0104 0.0103
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.004 0.0077
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0291 0.1758
Mycobacterium ulcerans hypothetical protein 0.0027 0.0089 0.0075
Plasmodium vivax hexose transporter 0.0211 0.1137 0.4429
Toxoplasma gondii ABC1 family protein 0.0076 0.0368 0.2227
Trichomonas vaginalis sugar transport protein, putative 0.003 0.0104 0.0195
Echinococcus multilocularis Aminotransferase class III 0.007 0.0335 0.0335
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.024 0.0594
Chlamydia trachomatis glutamate-1-semialdehyde-2,1-aminomutase 0.007 0.0335 0.3633
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0024 0.007 0.0075
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0099
Mycobacterium leprae PROBABLE GLUTAMATE-1-SEMIALDEHYDE 2,1-AMINOMUTASE HEML (GSA) (GLUTAMATE-1-SEMIALDEHYDE AMINOTRANSFERASE) (GSA-AT) 0.007 0.0335 0.1057
Plasmodium falciparum calcium-dependent protein kinase 4 0.0033 0.0123 0.0295
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Schistosoma mansoni hypothetical protein 0.0062 0.0286 0.0717
Brugia malayi beta-lactamase family protein 0.0076 0.0368 0.0702
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0299 0.0751
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0059 0.0059
Plasmodium falciparum mitogen-activated protein kinase 2 0.0172 0.0917 0.3522
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0059 0.0147
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0059 0.0013
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0021 0.0052 0.0097
Leishmania major myo-inositol/proton symporter (MIT) 0.003 0.0104 0.0412
Trichomonas vaginalis low molecular weight protein tyrosine phosphatase, putative 0.093 0.5247 1
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0307 0.1951
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0032 0.0115 0.0218
Mycobacterium tuberculosis Probable hydrolase 0.0076 0.0368 0.091
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0032 0.0116 0.0116
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0032 0.0115 0.0218
Mycobacterium ulcerans glutamate-1-semialdehyde aminotransferase 0.007 0.0335 0.0549
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0259 0.1411 0.269
Entamoeba histolytica calpain large subunit domain III containing protein 0.0019 0.0045 0.0009
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0299 0.0751
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0032 0.0116 0.0248
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.024 0.0594
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0078 0.0381 0.0956
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0089 0.017
Echinococcus multilocularis family C2 unassigned peptidase (C02 family) 0.0068 0.0325 0.0325
Echinococcus granulosus solute carrier family 22 0.003 0.0104 0.0257
Schistosoma mansoni glucose transporter 0.003 0.0104 0.026
Schistosoma mansoni protein kinase 0.0032 0.0115 0.0287
Onchocerca volvulus 0.0032 0.0115 0.012
Echinococcus granulosus calpain A 0.0019 0.0045 0.0112
Leishmania major glucose transporter, lmgt1 0.0065 0.0307 0.1744
Schistosoma mansoni sugar transporter 0.003 0.0104 0.026
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0059 0.0147
Echinococcus granulosus calpain 0.0019 0.0045 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0104 0.0195
Loa Loa (eye worm) hypothetical protein 0.0105 0.0534 0.1019
Schistosoma mansoni sugar transporter 0.003 0.0104 0.026
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0059 0.0112
Leishmania major glucose transporter, lmgt2 0.0065 0.0307 0.1744
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.024 0.13
Echinococcus granulosus glutamate NMDA receptor subunit 0.0062 0.0286 0.0709
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0093 0.0466 0.0466
Chlamydia trachomatis lysine--tRNA ligase 0.0024 0.007 0.0248
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.0089 0.0128
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0019 0.004 0.0251
Mycobacterium tuberculosis Probable ornithine aminotransferase (N-terminus part) RocD1 (ornithine--oxo-acid aminotransferase) 0.007 0.0335 0.0818
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0019 0.004 0.0251
Trypanosoma brucei glucose transporter 2A 0.0065 0.0307 0.1951
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0291 0.0463
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0019 0.004 0.0077
Schistosoma mansoni sugar transporter 0.003 0.0104 0.026
Brugia malayi AMP-binding enzyme family protein 0.0027 0.0089 0.017
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.0089 0.032
Brugia malayi ecdysteroid receptor 0.0022 0.0059 0.0112
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0052 0.0097
Echinococcus multilocularis calpain 7 (C02 family) 0.0019 0.0045 0.0045
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.024 0.13
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0059 0.0059
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0059 0.0112
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Echinococcus granulosus replication factor c subunit 1 0.0021 0.0052 0.0129
Schistosoma mansoni hypothetical protein 0.0377 0.2086 0.5232
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.002 0.0049 0.0015
Schistosoma mansoni metabotropic glutamate receptor 0.0032 0.0115 0.0287
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0045 0.0281
Trypanosoma cruzi kinesin, putative 0.0019 0.0045 0.0031
Loa Loa (eye worm) RNA binding protein 0.0064 0.0299 0.057
Trypanosoma brucei antigen, putative 0.0019 0.0045 0.0281
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0019 0.0041 0.0001
Entamoeba histolytica hypothetical protein 0.0021 0.0052 0.0022
Onchocerca volvulus 0.003 0.0104 0.0099
Brugia malayi calpain 7 0.0019 0.0045 0.0086
Mycobacterium ulcerans sugar transporter 0.003 0.0104 0.0103
Mycobacterium tuberculosis Conserved protein 0.0076 0.0368 0.091
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0032 0.0115 0.012
Loa Loa (eye worm) hypothetical protein 0.0073 0.0352 0.067
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0059 0.0013
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0037 0.0146 0.0882
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0059 0.0112
Mycobacterium ulcerans ornithine aminotransferase RocD1 and RocD2 0.007 0.0335 0.0549
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0096
Giardia lamblia Prolyl-tRNA synthetase 0.0032 0.0116 0.0146
Echinococcus multilocularis voltage dependent calcium channel subunit 0.0363 0.2006 0.2006
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0099
Mycobacterium tuberculosis Probable lipase LipD 0.0076 0.0368 0.091
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0052 0.0097
Leishmania major calpain, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0045 0.0031
Loa Loa (eye worm) hypothetical protein 0.0076 0.0368 0.0702
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0291 0.0291
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0368 0.0924
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0117 0.0604 0.1498
Trypanosoma brucei calpain-like protein, putative 0.0019 0.0045 0.0281
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0024 0.007 0.0192
Trypanosoma brucei hypothetical protein, conserved 0.0076 0.0368 0.2338
Echinococcus multilocularis lysyl tRNA synthetase 0.0024 0.007 0.007
Trichomonas vaginalis myo-inositol transporter, putative 0.003 0.0104 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Echinococcus granulosus solute carrier family 22 0.003 0.0104 0.0257
Echinococcus granulosus glutamate receptor 2 0.0032 0.0115 0.0284
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0032 0.0115 0.0115
Schistosoma mansoni hypothetical protein 0.0211 0.1137 0.2852
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Loa Loa (eye worm) hypothetical protein 0.0027 0.0089 0.017
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0037 0.0146 0.0693
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0032 0.0115 0.0218
Trypanosoma brucei glucose transporter, putative 0.0065 0.0307 0.1951
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.024 0.13
Loa Loa (eye worm) hypothetical protein 0.003 0.0104 0.0197
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.0089 0.0094
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0033 0.0123 0.0123
Trichomonas vaginalis replication factor C large subunit, putative 0.0021 0.0052 0.0097
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Trypanosoma brucei glucose transporter, putative 0.0065 0.0307 0.1951
Trypanosoma brucei sugar transporter, putative 0.003 0.0104 0.0653
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0093 0.0466 0.0466
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0059 0.0145
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0259 0.1411 0.269
Echinococcus granulosus tyrosine kinase 0.0032 0.0115 0.0284
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0211 0.1137 0.1137
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0291 0.0463
Loa Loa (eye worm) hypothetical protein 0.0046 0.0196 0.0373
Trypanosoma cruzi hypothetical protein, conserved 0.0287 0.1572 1
Schistosoma mansoni hypothetical protein 0.0177 0.0944 0.2368
Schistosoma mansoni ornithine--oxo-acid transaminase 0.007 0.0335 0.0841
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0052 0.0097
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0291 0.073
Schistosoma mansoni hypothetical protein 0.0377 0.2086 0.5232
Loa Loa (eye worm) hypothetical protein 0.0021 0.0052 0.0099
Trypanosoma cruzi hexose transporter 0.0065 0.0307 0.1744
Brugia malayi nuclear hormone receptor 0.0022 0.0059 0.0112
Schistosoma mansoni glutamate receptor AMPA 0.0062 0.0286 0.0717
Echinococcus granulosus microtubule associated protein 2 0.071 0.3987 0.9884
Schistosoma mansoni glutamate receptor kainate 0.0062 0.0286 0.0717
Loa Loa (eye worm) hypothetical protein 0.0027 0.0089 0.017
Toxoplasma gondii FATC domain-containing protein 0.0025 0.008 0.0479
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0024 0.007 0.0131
Loa Loa (eye worm) hypothetical protein 0.002 0.005 0.0096
Entamoeba histolytica protein kinase, putative 0.0022 0.0059 0.0036
Echinococcus granulosus GPCR family 2 0.0082 0.0402 0.0996
Brugia malayi Receptor family ligand binding region containing protein 0.0032 0.0115 0.0218
Schistosoma mansoni glutamate receptor NMDA 0.0062 0.0286 0.0717
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.0089 0.0075
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0115 0.0115
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.003 0.0104 0.0653
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0032 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0065 0.0306 0.0584
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0059 0.0112
Brugia malayi Calcitonin receptor-like protein seb-1 0.0259 0.1411 0.269
Onchocerca volvulus 0.003 0.0104 0.0099
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0059 0.0147
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0117 0.0604 0.1516
Trichomonas vaginalis penicillin-binding protein, putative 0.0076 0.0368 0.07
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Mycobacterium ulcerans hypothetical protein 0.0076 0.0368 0.0612
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0059 0.0145
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0013 0.0009 0.0017
Echinococcus granulosus voltage dependent calcium channel subunit 0.0165 0.0877 0.2173
Loa Loa (eye worm) hypothetical protein 0.0078 0.0381 0.0726
Brugia malayi Sugar transporter family protein 0.003 0.0104 0.0197
Echinococcus granulosus geminin 0.0377 0.2086 0.5172
Loa Loa (eye worm) sugar transporter 0.0211 0.1137 0.2167
Mycobacterium leprae Probable Acetylornithine aminotransferase ArgD 0.007 0.0335 0.1057
Trichomonas vaginalis esterase, putative 0.0076 0.0368 0.07
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Toxoplasma gondii transporter, major facilitator family protein 0.003 0.0104 0.0622
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0059 0.0147
Mycobacterium leprae Probable 4-aminobutyrate aminotransferase GabT (GAMMA-AMINO-N-BUTYRATE TRANSAMINASE) (GABA TRANSAMINASE) (GLUTAMATE:SUCCINIC SEM 0.007 0.0335 0.1057
Schistosoma mansoni lysyl-tRNA synthetase 0.0024 0.007 0.0175
Toxoplasma gondii Alpha-galactosidase 0.0017 0.0029 0.0171
Echinococcus multilocularis General substrate transporter 0.0181 0.0968 0.0968
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Echinococcus multilocularis beta LACTamase domain containing family member 0.0076 0.0368 0.0368
Loa Loa (eye worm) hypothetical protein 0.0032 0.0115 0.0218
Entamoeba histolytica protein kinase, putative 0.0033 0.0123 0.0158
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0291 0.0693
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0059 0.0112
Loa Loa (eye worm) latrophilin receptor protein 2 0.0082 0.0402 0.0766
Brugia malayi calpain 5 0.0019 0.0045 0.0086
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.002 0.0049 0.0015
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0076 0.0368 0.0924
Mycobacterium tuberculosis Probable glutamate-1-semialdehyde 2,1-aminomutase HemL (GSA) (glutamate-1-semialdehyde aminotransferase) (GSA-at) 0.007 0.0335 0.0818
Brugia malayi hypothetical protein 0.0029 0.0102 0.0194
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Plasmodium falciparum calcium-dependent protein kinase 2 0.0033 0.0123 0.0295
Trichomonas vaginalis WD repeat domain, putative 0.0076 0.0368 0.07
Trichomonas vaginalis sugar transporter, putative 0.003 0.0104 0.0195
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.0089 0.0075
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0211 0.1137 0.2819
Leishmania major protein kinase, putative 0.0033 0.0123 0.0538
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0497 0.0946
Trichomonas vaginalis PIKK family atypical protein kinase 0.0019 0.004 0.0075
Trypanosoma brucei glucose transporter 1E 0.0065 0.0307 0.1951
Brugia malayi Melibiase family protein 0.0078 0.0381 0.0726
Loa Loa (eye worm) glutamate receptor 0.0032 0.0115 0.0218
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0033 0.0123 0.0304
Echinococcus granulosus lysyl tRNA synthetase 0.0024 0.007 0.0173
Plasmodium vivax replication factor C subunit 1, putative 0.0021 0.0052 0.0028
Echinococcus multilocularis calpain 0.0019 0.0045 0.0045
Mycobacterium leprae PROBABLE ADENOSYLMETHIONINE-8-AMINO-7-OXONONANOATE AMINOTRANSFERASE BIOA 0.0494 0.2756 1
Toxoplasma gondii sugar transporter ST2 0.003 0.0104 0.0622
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0299 0.0299
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0497 0.1231
Echinococcus multilocularis glutamate receptor 2 0.0093 0.0466 0.0466
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0036 0.0142 0.0392
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0037 0.0146 0.0926
Onchocerca volvulus 0.003 0.0104 0.0099
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0019 0.0045 0.0031
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0076 0.0368 0.091
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.0113
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0019 0.004 0.0251
Mycobacterium leprae Probable lipase LipE 0.0076 0.0368 0.1179
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0102 0.023
Echinococcus multilocularis NMDA receptor 0.0062 0.0286 0.0286
Echinococcus granulosus glutamate receptor 2 0.0093 0.0466 0.1155
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.024 0.13
Loa Loa (eye worm) major facilitator superfamily transporter 0.003 0.0104 0.0197
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0033 0.0123 0.0315
Trichomonas vaginalis D-aminoacylase, putative 0.0076 0.0368 0.07
Loa Loa (eye worm) hypothetical protein 0.0022 0.0059 0.0112
Giardia lamblia Sugar-proton symporter 0.003 0.0104 0.0121
Loa Loa (eye worm) hypothetical protein 0.0033 0.0123 0.0234
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0059 0.0112

Activities

Activity type Activity value Assay description Source Reference
Inhibition (functional) < 30 % Antiexploratory activity (EXPL) of mice determined by an antimex activity meter, 50 mg/kg of dose was administered perorally; No inhibition ChEMBL. 2891853
Inhibition (functional) < 30 % Antireserpine activity (RES) of mice after peroral administration of 100 mg/kg of compound; No inhibition ChEMBL. 2891853
Inhibition (functional) < 30 % Antitremorine activity(TRM) of mice after peroral administration of 50 mg/kg of compound; No inhibition ChEMBL. 2891853

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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