Detailed information for compound 110174

Basic information

Technical information
  • TDR Targets ID: 110174
  • Name: hexadecyl(trimethyl)azanium bromide
  • MW: 364.447 | Formula: C19H42BrN
  • H donors: 0 H acceptors: 0 LogP: 9 Rotable bonds: 15
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-]
  • InChi: 1S/C19H42N.BrH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(2,3)4;/h5-19H2,1-4H3;1H/q+1;/p-1
  • InChiKey: LZZYPRNAOMGNLH-UHFFFAOYSA-M  


Substructure search Similarity search

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Synonyms

  • hexadecyl(trimethyl)ammonium bromide
  • cetyl(trimethyl)ammonium bromide
  • cetrimonium
  • hexadecylamine
  • hexadecyl-trimethylazanium bromide
  • hexadecyl-trimethyl-ammonium bromide
  • hexadecyl-trimethylammonium bromide
  • cetyl-trimethyl-ammonium bromide
  • hexadecyl-trimethyl-azanium bromide
  • 57-09-0
  • 104302-76-3
  • 108779-80-2
  • 12294-25-6
  • 6899-10-1
  • 69217-35-2
  • 79631-76-8
  • 52365_FLUKA
  • SBB008910
  • H6269_SIGMA
  • NCGC00095012-01
  • NCGC00095012-02
  • C11275
  • Cetrimonium bromide
  • Cetyltrimethylammonium bromide
  • Trimethylcetylammonium bromide
  • 1-Hexadecyltrimethylammonium bromide
  • Lissolamine V
  • H5882_SIGMA
  • Cetrimide
  • Cetrimonium bromide (NF)
  • D03454
  • SPECTRUM1503200
  • WLN: 16K1&1&1 &Q &E
  • H9151_SIGMA
  • (1-Hexadecyl)trimethylammonium bromide
  • 1-Hexadecanaminium, N,N,N-trimethyl-, bromide
  • AI3-12209
  • Acetoquat CTAB
  • Ammonium, hexadecyltrimethyl-, bromide
  • Bromat
  • Bromat (VAN)
  • Bromure de cetrimonium [INN-French]
  • Bromuro de cetrimonio [INN-Spanish]
  • CETAB
  • CTAB
  • Caswell No. 167
  • Cee dee
  • Centimide
  • Cetaflon
  • Cetarol
  • Cetavlon
  • Cetavlon bromide
  • Cetrimide bp
  • Cetrimonii bromidum [INN-Latin]
  • Cetrimonio bromuro [DCIT]
  • Cetrimonium bromide [INN]
  • Cetyl trimethyl ammonium bromide
  • Cirrasol OD
  • Cirrasol-OD
  • Ctmab
  • Cycloton V
  • EINECS 200-311-3
  • EPA Pesticide Chemical Code 069117
  • Hexadecyl trimethyl ammonium bromide
  • Hexadecyltrimethylammonium bromide
  • Lauroseptol
  • Lissolamin V
  • Lissolamine
  • Lissolamine A
  • Lissolamine V (VAN)
  • Mical
  • Micol
  • Micol (VAN)
  • N,N,N-Trimethyl-1-hexadecanaminium bromide
  • N,N,N-Trimethylcetylammonium bromide
  • N-Cetyltrimethylammonium bromide
  • N-HEXADECYLTRIMETHYLAMMONIUM BROMIDE
  • N-Hexadecyl-N,N,N-trimethylammonium bromide
  • NSC 32927
  • Palmityltrimethyl ammonium bromide
  • Pollacid
  • Quamonium
  • Softex KW
  • Suticide
  • Trimethylhexadecylammonium bromide
  • NSC32927
  • 52367_FLUKA
  • 36932_RIEDEL
  • Palmityltrimethylammonium bromide
  • CHEBI:3567
  • N,N,N-trimethylhexadecan-1-aminium bromide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens estrogen receptor 1 Starlite/ChEMBL No references
Homo sapiens galactosylceramidase No references
Homo sapiens retinoid X receptor, alpha Starlite/ChEMBL No references
Mus musculus RAR-related orphan receptor gamma Starlite/ChEMBL No references
Rattus norvegicus Peripheral myelin protein 22 Starlite/ChEMBL No references
Homo sapiens androgen receptor Starlite/ChEMBL No references
Homo sapiens geminin, DNA replication inhibitor Starlite/ChEMBL No references
Homo sapiens peroxisome proliferator-activated receptor delta Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens thyroid hormone receptor, beta Starlite/ChEMBL No references
Homo sapiens survival of motor neuron 2, centromeric Starlite/ChEMBL No references
Homo sapiens dynamin 1 Starlite/ChEMBL References
Homo sapiens microtubule-associated protein tau Starlite/ChEMBL No references
Homo sapiens lamin A/C Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Echinococcus granulosus cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Toxoplasma gondii dynamin gtpase Get druggable targets OG5_126660 All targets in OG5_126660
Cryptosporidium parvum dynamin-related protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Trichomonas vaginalis dynamin, putative Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma mansoni intermediate filament proteins Get druggable targets OG5_128723 All targets in OG5_128723
Toxoplasma gondii dynamin-related protein DRPA Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus granulosus survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Leishmania infantum GTP-binding protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Plasmodium knowlesi dynamin-like protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Trichomonas vaginalis interferon-induced GTP-binding protein mx, putative Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Echinococcus granulosus dynamin Get druggable targets OG5_126660 All targets in OG5_126660
Trichomonas vaginalis dynamin, putative Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma mansoni thyroid hormone receptor Get druggable targets OG5_134830 All targets in OG5_134830
Neospora caninum dynamin-like protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Thyroid hormone receptor alpha, putative Get druggable targets OG5_134830 All targets in OG5_134830
Theileria parva dynamin, putative Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus multilocularis lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma congolense dynamin-1-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma mansoni retinoic acid receptor RXR Get druggable targets OG5_130073 All targets in OG5_130073
Schistosoma japonicum ko:K08524 nuclear receptor, subfamily 2, group B, member 1, putative Get druggable targets OG5_130073 All targets in OG5_130073
Trichomonas vaginalis dynamin, putative Get druggable targets OG5_126660 All targets in OG5_126660
Brugia malayi Intermediate filament tail domain containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Entamoeba histolytica dynamin-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Trypanosoma brucei dynamin-1-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus multilocularis microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Plasmodium yoelii dynamin like protein-related Get druggable targets OG5_126660 All targets in OG5_126660
Brugia malayi Dynamin Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma mansoni thyroid hormone receptor Get druggable targets OG5_134830 All targets in OG5_134830
Schistosoma japonicum ko:K04380 microtubule-associated protein tau, putative Get druggable targets OG5_133504 All targets in OG5_133504
Babesia bovis dynamin central region family protein Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum ko:K01528 dynamin GTPase [EC3.6.5.5], putative Get druggable targets OG5_126660 All targets in OG5_126660
Brugia malayi intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus granulosus microtubule associated protein 2 Get druggable targets OG5_133504 All targets in OG5_133504
Leishmania major GTP-binding protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Candida albicans GTP-binding protein/GTPase Get druggable targets OG5_126660 All targets in OG5_126660
Cryptosporidium hominis dynamin-related protein Get druggable targets OG5_126660 All targets in OG5_126660
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis cytoplasmic intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Dynamin-1, putative Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum ko:K08362 nuclear receptor, subfamily 1, group A, member 2, putative Get druggable targets OG5_134830 All targets in OG5_134830
Babesia bovis dynamin-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Plasmodium vivax dynamin protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania mexicana GTP-binding protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Loa Loa (eye worm) intermediate filament tail domain-containing protein Get druggable targets OG5_128723 All targets in OG5_128723
Trypanosoma brucei gambiense dynamin, putative,vacuolar sortin protein 1, putative Get druggable targets OG5_126660 All targets in OG5_126660
Cryptosporidium parvum dynamin-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Trichomonas vaginalis dynamin, putative Get druggable targets OG5_126660 All targets in OG5_126660
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum expressed protein Get druggable targets OG5_134830 All targets in OG5_134830
Echinococcus granulosus dynamin 1 Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum Lamin-C, putative Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Dynamin Get druggable targets OG5_126660 All targets in OG5_126660
Giardia lamblia Dynamin Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum Dynamin-1, putative Get druggable targets OG5_126660 All targets in OG5_126660
Theileria parva hypothetical protein Get druggable targets OG5_126660 All targets in OG5_126660
Trichomonas vaginalis dynamin, putative Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus multilocularis dynamin 1 protein Get druggable targets OG5_126660 All targets in OG5_126660
Trypanosoma brucei gambiense dynamin, putative,vacuolar sortin protein 1, putative Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum expressed protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni dynamin Get druggable targets OG5_126660 All targets in OG5_126660
Onchocerca volvulus Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium falciparum dynamin-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania braziliensis GTP-binding protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Schistosoma japonicum Dynamin-1, putative Get druggable targets OG5_126660 All targets in OG5_126660
Candida albicans dynamin-related protein Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum ko:K01528 dynamin GTPase [EC3.6.5.5], putative Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal Get druggable targets OG5_134830 All targets in OG5_134830
Trichomonas vaginalis mgm1, putative Get druggable targets OG5_126660 All targets in OG5_126660
Candida albicans GTP-binding protein/GTPase Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum Dynamin-2, putative Get druggable targets OG5_126660 All targets in OG5_126660
Loa Loa (eye worm) DRP-1 protein Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma mansoni dynamin Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum Intermediate filament protein ifa-1, putative Get druggable targets OG5_128723 All targets in OG5_128723
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis musashi Get druggable targets OG5_128723 All targets in OG5_128723
Leishmania donovani dynamin-1-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis dynamin Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum Dynamin-1-like protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Plasmodium berghei dynamin-like protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus granulosus retinoic acid receptor rxr beta a Get druggable targets OG5_130073 All targets in OG5_130073
Toxoplasma gondii dynamin-related protein DRPB Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus multilocularis dynamin 1 Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus multilocularis survival motor neuron protein 1 Get druggable targets OG5_132873 All targets in OG5_132873
Schistosoma mansoni dynamin Get druggable targets OG5_126660 All targets in OG5_126660
Plasmodium knowlesi dynamin-like protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma mansoni hypothetical protein Get druggable targets OG5_134830 All targets in OG5_134830
Trypanosoma cruzi dynamin-1-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Trypanosoma brucei dynamin-1-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum ko:K07611 lamin, putative Get druggable targets OG5_128723 All targets in OG5_128723
Brugia malayi Dynamin central region family protein Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus granulosus lamin dm0 Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma japonicum Thyroid hormone receptor alpha, putative Get druggable targets OG5_134830 All targets in OG5_134830
Trichomonas vaginalis dynamin, putative Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma japonicum expressed protein Get druggable targets OG5_126660 All targets in OG5_126660
Schistosoma mansoni microtubule-associated protein tau Get druggable targets OG5_133504 All targets in OG5_133504
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal Get druggable targets OG5_134830 All targets in OG5_134830
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha Get druggable targets OG5_130073 All targets in OG5_130073
Brugia malayi hypothetical protein Get druggable targets OG5_132873 All targets in OG5_132873
Plasmodium berghei dynamin-like protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus granulosus intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Schistosoma mansoni lamin Get druggable targets OG5_128723 All targets in OG5_128723
Cryptosporidium hominis dynactin 4 (p62) Get druggable targets OG5_126660 All targets in OG5_126660
Plasmodium falciparum dynamin-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Neospora caninum Strain CBS138 chromosome D complete sequence, related Get druggable targets OG5_126660 All targets in OG5_126660
Loa Loa (eye worm) intermediate filament protein Get druggable targets OG5_128723 All targets in OG5_128723
Echinococcus multilocularis thyroid hormone receptor alpha Get druggable targets OG5_134830 All targets in OG5_134830
Plasmodium yoelii dynamin-like protein Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus granulosus lamin Get druggable targets OG5_128723 All targets in OG5_128723
Plasmodium vivax dynamin-like protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Echinococcus granulosus dynamin 1 protein Get druggable targets OG5_126660 All targets in OG5_126660
Entamoeba histolytica dynamin-1-like protein, putative Get druggable targets OG5_126660 All targets in OG5_126660
Plasmodium yoelii dynamin-like protein-related Get druggable targets OG5_126660 All targets in OG5_126660
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi hypothetical protein Peripheral myelin protein 22   160 aa 129 aa 25.6 %
Brugia malayi Hypothetical 65.5 kDa Trp-Asp repeats containing protein F02E8.5 inchromosome X geminin, DNA replication inhibitor 209 aa 176 aa 27.8 %
Brugia malayi ecdysteroid receptor peroxisome proliferator-activated receptor delta 441 aa 369 aa 24.7 %
Brugia malayi ecdysteroid receptor retinoid X receptor, alpha 435 aa 352 aa 23.9 %
Brugia malayi photoreceptor-specific nuclear receptor thyroid hormone receptor, beta 461 aa 414 aa 24.6 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma brucei phosphatidylinositol 3-kinase catalytic subunit, putative 0.00395794 0.0054685 0.0054685
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.00304162 0.00290751 0.00290751
Trichomonas vaginalis STE family protein kinase 0.00797042 0.0166828 0.0138155
Leishmania major phosphatidylinositol kinase, putative 0.00395794 0.0054685 0.0054685
Plasmodium falciparum histone deacetylase, putative 0.272019 0.754663 0.753314
Plasmodium vivax hypothetical protein, conserved 0.00939988 0.020678 0.0152931
Echinococcus granulosus histone deacetylase 6 0.272019 0.754663 0.753638
Trichomonas vaginalis PIKK family atypical protein kinase 0.0147934 0.0357522 0.0329405
Mycobacterium leprae Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0672407 0.182335 1
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0904426 0.247182 0.244987
Trypanosoma cruzi histone deacetylase 1, putative 0.3598 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0162496 0.0398219 0.0370221
Schistosoma mansoni phosphatidylinositol 4-kinase 0.00395794 0.0054685 0.001312
Trichomonas vaginalis PIKK family atypical protein kinase 0.01049 0.0237248 0.020878
Loa Loa (eye worm) histone deacetylase 0.272019 0.754663 0.754663
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.00395794 0.0054685 0.001312
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0590429 0.159424 0.159424
Echinococcus multilocularis acetylcholinesterase 0.00818585 0.0172849 0.0131778
Trichomonas vaginalis PIKK family atypical protein kinase 0.023176 0.0591805 0.056437
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, cytosolic 0.17825 0.492593 0.492593
Toxoplasma gondii FATC domain-containing protein 0.00699957 0.0139695 0.00854769
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.00395794 0.0054685 0.0054685
Entamoeba histolytica phosphatidylinositol 3-kinase 1, putative 0.0864846 0.23612 0.231919
Trichomonas vaginalis PIKK family atypical protein kinase 0.0158007 0.0385675 0.035764
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.023176 0.0591805 0.0591805
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0904426 0.247182 0.244987
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143991 0.0346501 0.0318351
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.17825 0.492593 0.490472
Schistosoma mansoni brca1-associated protein (brap2) 0.00939988 0.020678 0.0165851
Toxoplasma gondii Zn-finger in ubiquitin-hydrolases domain-containing protein 0.00939988 0.020678 0.0152931
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.031132 0.0814165 0.0763656
Trichomonas vaginalis PIKK family atypical protein kinase 0.023176 0.0591805 0.056437
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.0591617 0.159756 0.159756
Brugia malayi Histone deacetylase 1 0.3598 1 1
Toxoplasma gondii target of rapamycin (TOR), putative 0.0182839 0.0455076 0.0402593
Trypanosoma brucei Voltage-dependent calcium channel subunit, putative 0.0232591 0.0594128 0.0594128
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.17825 0.492593 0.492593
Trichomonas vaginalis PIKK family atypical protein kinase 0.00786697 0.0163937 0.0135255
Loa Loa (eye worm) phosphatidylinositol 3 0.00395794 0.0054685 0.0054685
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.11101 0.304664 0.304664
Entamoeba histolytica hypothetical protein 0.0722398 0.196307 0.191888
Echinococcus multilocularis integrin beta 2 0.192028 0.5311 0.52914
Loa Loa (eye worm) phosphatidylinositol 3 0.00395794 0.0054685 0.0054685
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0129293 0.0305422 0.0252116
Leishmania major phosphatidylinositol 4-kinase alpha, putative 0.0129293 0.0305422 0.0305422
Echinococcus granulosus histone deacetylase 1 0.3598 1 1
Schistosoma mansoni histone deacetylase 0.3598 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143749 0.0345824 0.0317673
Trichomonas vaginalis PIKK family atypical protein kinase 0.0192912 0.0483229 0.0455478
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.17825 0.492593 0.489803
Echinococcus granulosus histone deacetylase 3 0.3598 1 1
Brugia malayi hypothetical protein 0.0411781 0.109494 0.109494
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0904426 0.247182 0.244987
Brugia malayi Alpha-L-fucosidase family protein 0.0241763 0.0619761 0.0619761
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.00395794 0.0054685 0.00256846
Loa Loa (eye worm) alpha-L-fucosidase 0.0241763 0.0619761 0.0619761
Toxoplasma gondii histone deacetylase HDAC4 0.157184 0.433715 0.430601
Schistosoma mansoni histone deacetylase hda2 0.157184 0.433715 0.431348
Trypanosoma cruzi histone deacetylase 1, putative 0.3598 1 1
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0129293 0.0305422 0.0264905
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.17825 0.492593 0.490472
Loa Loa (eye worm) phosphatidylinositol 3 0.00395794 0.0054685 0.0054685
Brugia malayi histone deacetylase 3 (HD3) 0.3598 1 1
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0129293 0.0305422 0.0305422
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.492593
Trichomonas vaginalis brca1-associated protein, putative 0.00939988 0.020678 0.0178223
Toxoplasma gondii histone deacetylase HDAC1 0.272019 0.754663 0.753314
Trypanosoma brucei target of rapamycin kinase 3, putative 0.019267 0.0482552 0.0482552
Brugia malayi Carboxylesterase family protein 0.00818585 0.0172849 0.0172849
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.01049 0.0237248 0.0237248
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.01049 0.0237248 0.0237248
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.00395794 0.0054685 0.001312
Schistosoma mansoni brca1-associated protein (brap2) 0.00939988 0.020678 0.0165851
Trypanosoma cruzi histone deacetylase, putative 0.272019 0.754663 0.754663
Echinococcus granulosus voltage dependent calcium channel 0.00800569 0.0167814 0.0126722
Trichomonas vaginalis PIKK family atypical protein kinase 0.01049 0.0237248 0.020878
Schistosoma mansoni family C19 non-peptidase homologue (C19 family) 0.00939988 0.020678 0.0165851
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.00939988 0.020678 0.020678
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182839 0.0455076 0.0427243
Plasmodium falciparum U4/U6.U5 tri-snRNP-associated protein 2, putative 0.00939988 0.020678 0.0152931
Echinococcus multilocularis voltage dependent calcium channel 0.0382352 0.101269 0.0975129
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.0591617 0.159756 0.157306
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.00395794 0.0054685 0.0054685
Leishmania major hypothetical protein, unknown function 0.00395794 0.0054685 0.0054685
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.023176 0.0591805 0.0540073
Trichomonas vaginalis histone deacetylase, putative 0.3598 1 1
Trypanosoma brucei histone deacetylase 1 0.3598 1 1
Echinococcus multilocularis u4:u6.u5 tri snrnp associated protein 2 0.00939988 0.020678 0.0165851
Trichomonas vaginalis PIKK family atypical protein kinase 0.023176 0.0591805 0.056437
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.01049 0.0237248 0.0237248
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.00818585 0.0172849 0.0131778
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.00939988 0.020678 0.020678
Loa Loa (eye worm) hypothetical protein 0.114835 0.315355 0.315355
Plasmodium vivax ubiquitin carboxyl-terminal hydrolase 13, putative 0.00939988 0.020678 0.0152931
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.3598 1 1
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.119089 0.327244 0.324432
Echinococcus multilocularis 0.00395794 0.0054685 0.001312
Trichomonas vaginalis conserved hypothetical protein 0.00744841 0.0152239 0.0123523
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.00699957 0.0139695 0.00984847
Leishmania major phosphatidylinositol 3-kinase, putative 0.0129293 0.0305422 0.0305422
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0625317 0.169175 0.166752
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.00939988 0.020678 0.0178223
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.00939988 0.020678 0.020678
Loa Loa (eye worm) histone deacetylase 11 0.157184 0.433715 0.433715
Loa Loa (eye worm) hypothetical protein 0.00395794 0.0054685 0.0054685
Plasmodium vivax histone deacetylase 2, putative 0.272019 0.754663 0.753314
Loa Loa (eye worm) hypothetical protein 0.00699957 0.0139695 0.0139695
Echinococcus granulosus histone deacetylase 6 0.281419 0.780935 0.780019
Leishmania major phosphatidylinositol 4-kinase, putative 0.00395794 0.0054685 0.0054685
Leishmania major histone deacetylase, putative 0.272019 0.754663 0.754663
Treponema pallidum glyceraldehyde 3-phosphate dehydrogenase (gap) 0.17825 0.492593 0.5
Plasmodium vivax histone deacetylase, putative 0.272019 0.754663 0.753314
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.00699957 0.0139695 0.0139695
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0904426 0.247182 0.243042
Toxoplasma gondii UBA/TS-N domain-containing protein 0.00939988 0.020678 0.0152931
Trichomonas vaginalis alpha-L-fucosidase, putative 0.00971519 0.0215593 0.0187061
Loa Loa (eye worm) voltage-dependent calcium channel 0.00800569 0.0167814 0.0167814
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.00797042 0.0166828 0.0166828
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.051848 0.139315 0.139315
Trichomonas vaginalis STE family protein kinase 0.00797042 0.0166828 0.0138155
Trypanosoma cruzi phosphatidylinositol kinase, putative 0.00395794 0.0054685 0.0054685
Loa Loa (eye worm) hypothetical protein 0.3598 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.00699957 0.0139695 0.0110942
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.00939988 0.020678 0.020678
Mycobacterium ulcerans alpha-L-fucosidase 0.0504952 0.135534 0.275144
Echinococcus multilocularis fucosidase, alpha L 1, tissue 0.0504952 0.135534 0.131921
Loa Loa (eye worm) hypothetical protein 0.00818585 0.0172849 0.0172849
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0625317 0.169175 0.166752
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0129293 0.0305422 0.0305422
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.00395794 0.0054685 0.001312
Schistosoma mansoni fkbp-rapamycin associated protein 0.00699957 0.0139695 0.00984847
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0590429 0.159424 0.155911
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.00939988 0.020678 0.020678
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.00699957 0.0139695 0.0139695
Loa Loa (eye worm) hypothetical protein 0.124235 0.341627 0.341627
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.031132 0.0814165 0.0814165
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.17825 0.492593 0.489803
Trichomonas vaginalis alpha-L-fucosidase, putative 0.00971519 0.0215593 0.0187061
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.00939988 0.020678 0.020678
Echinococcus granulosus voltage dependent L type calcium channel subunit|voltage dependent calcium channel 0.0382352 0.101269 0.0975129
Trichomonas vaginalis PIKK family atypical protein kinase 0.0147934 0.0357522 0.0329405
Loa Loa (eye worm) hypothetical protein 0.00744841 0.0152239 0.0152239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182839 0.0455076 0.0427243
Trypanosoma cruzi histone deacetylase, putative 0.157184 0.433715 0.433715
Toxoplasma gondii histone deacetylase HDAC3 0.3598 1 1
Loa Loa (eye worm) ubiquitin carboxyl-terminal hydrolase 0.00939988 0.020678 0.020678
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.00395794 0.0054685 0.00256846
Mycobacterium ulcerans glyceraldehyde 3-phosphate dehydrogenase Gap 0.17825 0.492593 1
Loa Loa (eye worm) hypothetical protein 0.0313997 0.0821646 0.0821646
Loa Loa (eye worm) hypothetical protein 0.00304162 0.00290751 0.00290751
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.051848 0.139315 0.139315
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.051848 0.139315 0.139315
Echinococcus granulosus c-Jun N-terminal kinases 0.0231588 0.0591325 0.0552003
Echinococcus granulosus dual specificity mitogen activated protein 0.00797042 0.0166828 0.0125732
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.00395794 0.0054685 0.001312
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.00699957 0.0139695 0.00854769
Giardia lamblia Histone deacetylase 0.3598 1 1
Loa Loa (eye worm) hypothetical protein 0.00818585 0.0172849 0.0172849
Brugia malayi histone deacetylase 1 (HD1) 0.3598 1 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.01049 0.0237248 0.020878
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0904426 0.247182 0.247182
Trichomonas vaginalis PIKK family atypical protein kinase 0.0196855 0.0494251 0.0466532
Trypanosoma cruzi Voltage-dependent calcium channel subunit, putative 0.0232591 0.0594128 0.0594128
Echinococcus granulosus serine protein kinase ATM 0.00699957 0.0139695 0.00984847
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.00939988 0.020678 0.020678
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0117518 0.0272513 0.0272513
Onchocerca volvulus 0.0224432 0.0571323 0.12064
Plasmodium vivax U4/U6.U5 tri-snRNP-associated protein 2, putative 0.00939988 0.020678 0.0152931
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0224432 0.0571323 0.0571323
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0382352 0.101269 0.0975129
Trichomonas vaginalis PIKK family atypical protein kinase 0.01049 0.0237248 0.020878
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0590429 0.159424 0.155911
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0382352 0.101269 0.0975129
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.00797042 0.0166828 0.0166828
Giardia lamblia Phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.044329 0.1183 0.113452
Trichomonas vaginalis PIKK family atypical protein kinase 0.00395794 0.0054685 0.00256846
Leishmania major glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.17825 0.492593 0.492593
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.00395794 0.0054685 0.001312
Schistosoma mansoni ubiquitin-specific peptidase 5 (C19 family) 0.00939988 0.020678 0.0165851
Trypanosoma cruzi target of rapamycin kinase 3 0.019267 0.0482552 0.0482552
Schistosoma mansoni hypothetical protein 0.00395794 0.0054685 0.001312
Echinococcus multilocularis voltage dependent L type calcium channel subunit 0.0382352 0.101269 0.0975129
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.00395794 0.0054685 0.001312
Entamoeba histolytica Sir2 family transcriptional regulator, putative 0.00939988 0.020678 0.0152931
Brugia malayi glyceraldehyde 3-phosphate dehydrogenase 0.051848 0.139315 0.139315
Trichomonas vaginalis PIKK family atypical protein kinase 0.0192912 0.0483229 0.0455478
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.031132 0.0814165 0.0787379
Trichomonas vaginalis PIKK family atypical protein kinase 0.0153822 0.0373977 0.0345907
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.168942 0.466577 0.464347
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.01049 0.0237248 0.0237248
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.00699957 0.0139695 0.0139695
Loa Loa (eye worm) hypothetical protein 0.119089 0.327244 0.327244
Toxoplasma gondii histone deacetylase HDAC5 0.157184 0.433715 0.430601
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase 5, putative 0.00939988 0.020678 0.0152931
Echinococcus multilocularis sodium channel protein 0.0162191 0.0397368 0.0357235
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.023176 0.0591805 0.0552484
Echinococcus granulosus histone deacetylase 8 0.157184 0.433715 0.431348
Leishmania major phosphatidylinositol 3-related kinase, putative 0.01049 0.0237248 0.0237248
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.491114
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.491114
Leishmania major histone deacetylase, putative 0.272019 0.754663 0.754663
Echinococcus multilocularis histone deacetylase 3 0.3598 1 1
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.119089 0.327244 0.327244
Wolbachia endosymbiont of Brugia malayi glyceraldehyde-3-phosphate dehydrogenase, GapA 0.17825 0.492593 0.5
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143749 0.0345824 0.0317673
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.00797042 0.0166828 0.0166828
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.126402 0.347685 0.347685
Echinococcus multilocularis histone deacetylase 6 0.281419 0.780935 0.780019
Leishmania major histone deacetylase, putative 0.3598 1 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 14 0.00939988 0.020678 0.0152931
Echinococcus granulosus histone deacetylase 6 0.272019 0.754663 0.753638
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143749 0.0345824 0.0317673
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.17825 0.492593 0.490472
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.17825 0.492593 0.490472
Trypanosoma brucei Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.00939988 0.020678 0.020678
Echinococcus granulosus histone deacetylase 7 0.272019 0.754663 0.753638
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.01049 0.0237248 0.0196446
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182839 0.0455076 0.0427243
Echinococcus multilocularis BRCA1 associated protein 0.00939988 0.020678 0.0165851
Schistosoma mansoni histone deacetylase 1 2 3 0.157184 0.433715 0.431348
Trichomonas vaginalis PIKK family atypical protein kinase 0.00395794 0.0054685 0.00256846
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.00395794 0.0054685 0.0054685
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0411781 0.109494 0.109494
Brugia malayi phosphoinositide 3'-hydroxykinase p110-alpha subunit, putative 0.0784993 0.213802 0.213802
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.492593
Trichomonas vaginalis PIKK family atypical protein kinase 0.0192912 0.0483229 0.0455478
Toxoplasma gondii phosphatidylinositol 3- and 4-kinase 0.0129293 0.0305422 0.0252116
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0129293 0.0305422 0.0264905
Trypanosoma cruzi Emopamil binding protein, putative 0.0224432 0.0571323 0.0571323
Loa Loa (eye worm) histone deacetylase 7A 0.272019 0.754663 0.754663
Chlamydia trachomatis glyceraldehyde-3-phosphate dehydrogenase 0.17825 0.492593 0.5
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.17825 0.492593 0.490472
Leishmania major phosphatidylinositol 3-kinase, putative 0.01049 0.0237248 0.0237248
Trichomonas vaginalis STE family protein kinase 0.00797042 0.0166828 0.0138155
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.00939988 0.020678 0.0178223
Giardia lamblia Kinase, STE STE20 0.00797042 0.0166828 0.011276
Trichomonas vaginalis BRCA1-associated protein, putative 0.00939988 0.020678 0.0178223
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.031132 0.0814165 0.0787379
Onchocerca volvulus Histone deacetylase 10 homolog 0.157184 0.433715 1
Echinococcus granulosus fucosidase alpha L 1 tissue 0.0504952 0.135534 0.131921
Schistosoma mansoni protein kinase 0.00797042 0.0166828 0.0125732
Loa Loa (eye worm) hypothetical protein 0.00800569 0.0167814 0.0167814
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.17825 0.492593 0.489803
Brugia malayi Glyceraldehyde 3-phosphate dehydrogenase 0.17825 0.492593 0.492593
Trichomonas vaginalis histone deacetylase, putative 0.3598 1 1
Trichomonas vaginalis histone deacetylase, putative 0.3598 1 1
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.491114
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.00395794 0.0054685 0.0054685
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.492593
Echinococcus multilocularis voltage dependent calcium channel type d subunit 0.0382352 0.101269 0.0975129
Trypanosoma cruzi phosphatidylinositol 3-kinase vps34-like 0.031132 0.0814165 0.0814165
Loa Loa (eye worm) phosphatidylinositol kinase 0.00395794 0.0054685 0.0054685
Leishmania major hypothetical protein, conserved 0.00939988 0.020678 0.020678
Echinococcus multilocularis serine protein kinase ATM 0.00699957 0.0139695 0.00984847
Echinococcus granulosus carboxylesterase 5A 0.00818585 0.0172849 0.0131778
Echinococcus granulosus acetylcholinesterase 0.00818585 0.0172849 0.0131778
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.00939988 0.020678 0.020678
Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, putative 0.11101 0.304664 0.304664
Echinococcus multilocularis histone deacetylase 6 0.272019 0.754663 0.753638
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.00395794 0.0054685 0.0054685
Trichomonas vaginalis histone deacetylase, putative 0.3598 1 1
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.168942 0.466577 0.464347
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 5 0.00939988 0.020678 0.0165851
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0382352 0.101269 0.0975129
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0129293 0.0305422 0.0264905
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.023176 0.0591805 0.0591805
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0129293 0.0305422 0.0264905
Trypanosoma cruzi histone deacetylase, putative 0.272019 0.754663 0.754663
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0224432 0.0571323 0.0571323
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu 0.0382352 0.101269 0.0975129
Schistosoma mansoni integrin beta subunit 0.15085 0.416013 0.413572
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0382352 0.101269 0.0975129
Trichomonas vaginalis conserved hypothetical protein 0.00349047 0.00416196 0.00125811
Trypanosoma cruzi Emopamil binding protein, putative 0.0224432 0.0571323 0.0571323
Loa Loa (eye worm) hypothetical protein 0.00704005 0.0140826 0.0140826
Echinococcus granulosus voltage dependent calcium channel 0.0382352 0.101269 0.0975129
Echinococcus multilocularis histone deacetylase 8 0.157184 0.433715 0.431348
Leishmania major phosphatidylinositol kinase related protein, putative 0.00395794 0.0054685 0.0054685
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0408401 0.108549 0.103648
Toxoplasma gondii ubiquitin specific protease 39 isoform 2, putative 0.00939988 0.020678 0.0152931
Giardia lamblia Phosphoinositide-3-kinase, class 3 0.0221607 0.0563427 0.051154
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain, putative 0.051848 0.139315 0.139315
Giardia lamblia GTOR 0.023176 0.0591805 0.0540073
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.00395794 0.0054685 0.0054685
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.019267 0.0482552 0.0482552
Loa Loa (eye worm) hypothetical protein 0.0382352 0.101269 0.101269
Loa Loa (eye worm) hypothetical protein 0.0411781 0.109494 0.109494
Brugia malayi Integrin beta pat-3 precursor 0.262273 0.727426 0.727426
Echinococcus granulosus u4:u6.u5 tri snrnp associated protein 2 0.00939988 0.020678 0.0165851
Plasmodium falciparum histone deacetylase 1 0.3598 1 1
Mycobacterium tuberculosis Probable glyceraldehyde 3-phosphate dehydrogenase Gap (GAPDH) 0.0672407 0.182335 1
Loa Loa (eye worm) phosphatidylinositol 3 0.01049 0.0237248 0.0237248
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.491114
Trypanosoma brucei Emopamil binding protein, putative 0.0224432 0.0571323 0.0571323
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.023176 0.0591805 0.0591805
Loa Loa (eye worm) ubiquitin specific peptidase 39 0.00939988 0.020678 0.020678
Trichomonas vaginalis PIKK family atypical protein kinase 0.0192912 0.0483229 0.0455478
Schistosoma mansoni glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) 0.17825 0.492593 0.490472
Trichomonas vaginalis PIKK family atypical protein kinase 0.0192912 0.0483229 0.0455478
Brugia malayi Histone deacetylase family protein 0.272019 0.754663 0.754663
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.17825 0.492593 0.492593
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0904426 0.247182 0.247182
Brugia malayi FAT domain containing protein 0.00349047 0.00416196 0.00416196
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.168942 0.466577 0.464347
Plasmodium falciparum phosphatidylinositol 3-kinase 0.0129293 0.0305422 0.0252116
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.031132 0.0814165 0.0775774
Trypanosoma cruzi Ring finger domain/Zn-finger in ubiquitin-hydrolases and other protein, putative 0.00939988 0.020678 0.020678
Leishmania major hypothetical protein, conserved 0.0224432 0.0571323 0.0571323
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.031132 0.0814165 0.0763656
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143749 0.0345824 0.0317673
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.00939988 0.020678 0.020678
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.023176 0.0591805 0.0552484
Loa Loa (eye worm) glyceraldehyde 3-phosphate dehydrogenase 0.119089 0.327244 0.327244
Trypanosoma cruzi phosphatidylinositol 4-kinase, putative 0.00395794 0.0054685 0.0054685
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.01049 0.0237248 0.0237248
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0113332 0.0260815 0.0260815
Schistosoma mansoni histone deacetylase 0.3598 1 1
Leishmania major glyceraldehyde-3-phosphate dehydrogenase-like protein 0.11101 0.304664 0.304664
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143991 0.0346501 0.0318351
Loa Loa (eye worm) phosphatidylinositol 3 0.00395794 0.0054685 0.0054685
Trichomonas vaginalis PIKK family atypical protein kinase 0.0147934 0.0357522 0.0329405
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.17825 0.492593 0.492593
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.023176 0.0591805 0.0591805
Trypanosoma cruzi Zn-finger in ubiquitin-hydrolases and other protein, putative 0.00939988 0.020678 0.020678
Trypanosoma brucei histone deacetylase, putative 0.272019 0.754663 0.754663
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.3598 1 1
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.023176 0.0591805 0.0540073
Toxoplasma gondii non-specific serine/threonine protein kinase 0.00744841 0.0152239 0.00980904
Schistosoma mansoni histone deacetylase 4 5 0.272019 0.754663 0.753638
Onchocerca volvulus Uncharacterized RING finger protein homolog 0.00939988 0.020678 0.0355158
Trichomonas vaginalis PIKK family atypical protein kinase 0.00699957 0.0139695 0.0110942
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.119089 0.327244 0.325282
Loa Loa (eye worm) phosphatidylinositol 3 0.150739 0.415703 0.415703
Echinococcus granulosus voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 0.0382352 0.101269 0.0975129
Echinococcus multilocularis voltage dependent calcium channel 0.0382352 0.101269 0.0975129
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.00797042 0.0166828 0.0166828
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.492593
Trichomonas vaginalis histone deacetylase, putative 0.3598 1 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.023176 0.0591805 0.0591805
Loa Loa (eye worm) hypothetical protein 0.0590429 0.159424 0.159424
Echinococcus multilocularis dual specificity mitogen activated protein 0.00797042 0.0166828 0.0125732
Schistosoma mansoni histone deacetylase 4 5 0.272019 0.754663 0.753638
Trichomonas vaginalis PIKK family atypical protein kinase 0.01049 0.0237248 0.020878
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.031132 0.0814165 0.0787379
Schistosoma mansoni serine/threonine protein kinase 0.0231588 0.0591325 0.0552003
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182839 0.0455076 0.0427243
Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase, putative 0.11101 0.304664 0.304664
Loa Loa (eye worm) acetylcholinesterase 1 0.00818585 0.0172849 0.0172849
Trypanosoma cruzi phosphatidylinositol 3-kinase 2, putative 0.0904426 0.247182 0.247182
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0224432 0.0571323 0.0571323
Echinococcus multilocularis carboxylesterase 5A 0.00818585 0.0172849 0.0131778
Echinococcus multilocularis glyceraldehyde 3 phosphate dehydrogenase 0.119089 0.327244 0.324432
Entamoeba histolytica histone deacetylase, putative 0.3598 1 1
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0162191 0.0397368 0.0357235
Plasmodium vivax glyceraldehyde-3-phosphate dehydrogenase, putative 0.17825 0.492593 0.489803
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182839 0.0455076 0.0427243
Plasmodium vivax histone deacetylase, putative 0.157184 0.433715 0.430601
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0129293 0.0305422 0.0277153
Echinococcus granulosus integrin beta 2 0.192028 0.5311 0.52914
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.023176 0.0591805 0.0552484
Entamoeba histolytica protein kinase rad3, putative 0.00699957 0.0139695 0.00854769
Trypanosoma brucei histone deacetylase 3 0.272019 0.754663 0.754663
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.00939988 0.020678 0.0178223
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase, putative 0.00939988 0.020678 0.0152931
Entamoeba histolytica hypothetical protein 0.00699957 0.0139695 0.00854769
Loa Loa (eye worm) histone deacetylase 1 0.3598 1 1
Loa Loa (eye worm) histone deacetylase 3 0.3598 1 1
Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenase 0.17825 0.492593 0.489803
Trypanosoma brucei histone deacetylase 2 0.157184 0.433715 0.433715
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.17825 0.492593 0.492593
Entamoeba histolytica phosphatidylinositol 3-kinase, putative 0.0722398 0.196307 0.191888
Loa Loa (eye worm) glyceraldehyde-3-phosphate dehydrogenase 0.126402 0.347685 0.347685
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.00395794 0.0054685 0.001312
Leishmania major hypothetical protein, conserved 0.00395794 0.0054685 0.0054685
Loa Loa (eye worm) hypothetical protein 0.00704005 0.0140826 0.0140826
Giardia lamblia Hypothetical protein 0.00939988 0.020678 0.0152931
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.00797042 0.0166828 0.0166828
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.00395794 0.0054685 0.0054685
Loa Loa (eye worm) integrin beta-2 0.262273 0.727426 0.727426
Echinococcus granulosus acetylcholinesterase 0.00818585 0.0172849 0.0131778
Brugia malayi Carboxylesterase family protein 0.00818585 0.0172849 0.0172849
Loa Loa (eye worm) hypothetical protein 0.00349047 0.00416196 0.00416196
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.00939988 0.020678 0.0178223
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.17825 0.492593 0.491114
Loa Loa (eye worm) phosphatidylinositol 3 0.0271741 0.0703545 0.0703545
Schistosoma mansoni ubiquitin-specific peptidase 44 (C19 family) 0.00939988 0.020678 0.0165851
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0271741 0.0703545 0.0703545
Loa Loa (eye worm) phosphatidylinositol 3 0.023176 0.0591805 0.0591805
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.00939988 0.020678 0.0178223
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0129293 0.0305422 0.0264905
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH2 0.17825 0.492593 0.489803
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.023176 0.0591805 0.0591805
Toxoplasma gondii hypothetical protein 0.00704005 0.0140826 0.00866145
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.00699957 0.0139695 0.00984847
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.17825 0.492593 0.490472
Loa Loa (eye worm) hypothetical protein 0.00390902 0.00533178 0.00533178
Schistosoma mansoni alpha-l-fucosidase 0.0241763 0.0619761 0.0580557
Trichomonas vaginalis histone deacetylase 1, 2 ,3, putative 0.3598 1 1
Loa Loa (eye worm) BRCA1-associated protein 2 containing protein 0.00939988 0.020678 0.020678
Schistosoma mansoni histone deacetylase hda2 0.281419 0.780935 0.780019
Plasmodium falciparum ubiquitin carboxyl-terminal hydrolase 13, putative 0.00939988 0.020678 0.0152931
Echinococcus multilocularis Zinc finger, PHD finger 0.0129293 0.0305422 0.0264905
Loa Loa (eye worm) carboxylesterase 0.00818585 0.0172849 0.0172849
Echinococcus multilocularis histone deacetylase 7 0.272019 0.754663 0.753638
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0129293 0.0305422 0.0305422
Entamoeba histolytica phosphatidylinositol 4-kinase, putative 0.0129293 0.0305422 0.0252116
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0129293 0.0305422 0.0277153
Echinococcus multilocularis acetylcholinesterase 0.00818585 0.0172849 0.0131778
Trypanosoma cruzi histone deacetylase, putative 0.272019 0.754663 0.754663
Echinococcus multilocularis histone deacetylase 0.272019 0.754663 0.753638
Trichomonas vaginalis PIKK family atypical protein kinase 0.0143991 0.0346501 0.0318351
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.01049 0.0237248 0.0196446
Toxoplasma gondii transporter, cation channel family protein 0.00800569 0.0167814 0.0113751
Brugia malayi Stress-activated protein kinase jnk-1 0.0231588 0.0591325 0.0591325
Giardia lamblia Glyceraldehyde 3-phosphate dehydrogenase 0.11101 0.304664 0.300841
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.01049 0.0237248 0.0196446
Leishmania major histone deacetylase, putative 0.3598 1 1
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.00395794 0.0054685 0.001312
Brugia malayi Histone deacetylase family protein 0.272019 0.754663 0.754663
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182839 0.0455076 0.0427243
Echinococcus granulosus glyceraldehyde 3 phosphate dehydrogenase 0.17825 0.492593 0.490472
Echinococcus multilocularis histone deacetylase 1 0.3598 1 1
Brugia malayi histone deacetylase 11 0.157184 0.433715 0.433715
Loa Loa (eye worm) hypothetical protein 0.157184 0.433715 0.433715
Plasmodium falciparum histone deacetylase 2 0.272019 0.754663 0.753314
Trypanosoma brucei histone deacetylase 4 0.272019 0.754663 0.754663
Schistosoma mansoni voltage-gated cation channel 0.0382352 0.101269 0.0975129
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.00939988 0.020678 0.020678
Trichomonas vaginalis PIKK family atypical protein kinase 0.0153822 0.0373977 0.0345907
Echinococcus multilocularis histone deacetylase 6 0.272019 0.754663 0.753638
Plasmodium vivax phosphatidylinositol 3-kinase, putative 0.0129293 0.0305422 0.0252116
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 22 0.00939988 0.020678 0.0165851
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, putative 0.051848 0.139315 0.139315
Trypanosoma brucei Zn-finger in ubiquitin-hydrolases and other protein, putative 0.00939988 0.020678 0.020678
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.00939988 0.020678 0.0152931
Trypanosoma cruzi histone deacetylase, putative 0.157184 0.433715 0.433715
Trichomonas vaginalis glyceraldehyde 3-phosphate dehydrogenase, putative 0.119089 0.327244 0.325282
Trypanosoma cruzi glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative 0.17825 0.492593 0.492593
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.00395794 0.0054685 0.001312
Brugia malayi Voltage-gated calcium channel, L-type, alpha subunit. C. elegans egl-19 ortholog 0.0382352 0.101269 0.101269
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.031132 0.0814165 0.0814165
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.00699957 0.0139695 0.0139695
Trypanosoma brucei glyceraldehyde 3-phosphate dehydrogenase, glycosomal 0.17825 0.492593 0.492593
Plasmodium vivax histone deacetylase 1, putative 0.3598 1 1
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 22 0.00939988 0.020678 0.0165851
Echinococcus granulosus histone deacetylase 0.272019 0.754663 0.753638
Trichomonas vaginalis PIKK family atypical protein kinase 0.0182839 0.0455076 0.0427243
Trypanosoma cruzi phosphatidylinositol 4-kinase alpha, putative 0.0129293 0.0305422 0.0305422
Trypanosoma brucei phosphatidylinositol 4-kinase alpha, putative 0.0129293 0.0305422 0.0305422
Entamoeba histolytica glyceraldehyde-3-phosphate dehydrogenase, putative 0.17825 0.492593 0.489803
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0129293 0.0305422 0.0277153
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.00699957 0.0139695 0.0139695
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0231588 0.0591325 0.0552003
Trichomonas vaginalis histone deacetylase, putative 0.3598 1 1
Loa Loa (eye worm) calcium channel 0.0382352 0.101269 0.101269
Echinococcus granulosus BRCA1 associated protein 0.00939988 0.020678 0.0165851
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.023176 0.0591805 0.0591805
Brugia malayi Kelch motif family protein 0.0411781 0.109494 0.109494
Entamoeba histolytica phosphatidylinositol-4,5-bisphosphate 3-kinase, putative 0.0129293 0.0305422 0.0252116
Brugia malayi BRCA1-associated protein 2 containing protein 0.00939988 0.020678 0.020678
Toxoplasma gondii histone deacetylase HDAC2 0.3598 1 1
Leishmania major hypothetical protein, conserved 0.00939988 0.020678 0.020678
Trichomonas vaginalis PIKK family atypical protein kinase 0.00699957 0.0139695 0.0110942
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0231588 0.0591325 0.0591325
Toxoplasma gondii glyceraldehyde-3-phosphate dehydrogenase GAPDH1 0.17825 0.492593 0.489803
Echinococcus granulosus serine:threonine protein kinase SMG1 0.00699957 0.0139695 0.00984847

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) Induction of plasma membrane disruption in Escherichia coli ATCC 25922 at 2 mg/mL after 2 hrs by Sytox dye based assay ChEMBL. 21937226
Activity (functional) Induction of plasma membrane disruption in Escherichia coli ATCC 25922 at 2 mg/mL after 10 mins by Sytox dye based assay ChEMBL. 21937226
Activity (functional) 0 Inhibition of phosphatidyl choline biosynthesis in Plasmodium falcipuram NF54 assessed as [methlyl-14C]choline incorporation ChEMBL. 17145794
Activity (binding) 0 Inhibition of Plasmodium falciparum choline kinase ChEMBL. 17145794
Activity (binding) 0 Inhibition of synthetic amyloid beta42 fibrillization by light scattering analysis relative to control ChEMBL. 17284452
Activity (binding) 0 Inhibition of synthetic amyloid beta42 oligomer formation by Western blot ChEMBL. 17284452
Activity (binding) 0 Inhibition of synthetic amyloid beta42 fibrillization at 300 uM by light scattering analysis relative to control ChEMBL. 17284452
Activity (binding) 0 Inhibition of synthetic amyloid beta42 fibrillization at 30 uM by light scattering analysis relative to control ChEMBL. 17284452
Activity (functional) = 36.77 % Antimalarial activity against intraperitoneally inoculated Plasmodium yoelii N-67 in Swiss mouse at 5 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 36.77 % Antimalarial activity against intraperitoneally inoculated Plasmodium yoelii N-67 in Swiss mouse at 5 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 48.7 % Antimalarial activity against intravenously inoculated Plasmodium yoelii N-67 in Swiss mouse at 5 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 48.7 % Antimalarial activity against intravenously inoculated Plasmodium yoelii N-67 in Swiss mouse at 5 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 52.44 % Antimalarial activity against intraperitoneally inoculated Plasmodium yoelii N-67 in Swiss mouse at 10 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 52.44 % Antimalarial activity against intraperitoneally inoculated Plasmodium yoelii N-67 in Swiss mouse at 10 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 64.25 % Antimalarial activity against intravenously inoculated Plasmodium yoelii N-67 in Swiss mouse at 10 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 64.25 % Antimalarial activity against intravenously inoculated Plasmodium yoelii N-67 in Swiss mouse at 10 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 77.17 % Antimalarial activity against intraperitoneally inoculated Plasmodium yoelii N-67 in Swiss mouse at 20 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 77.17 % Antimalarial activity against intraperitoneally inoculated Plasmodium yoelii N-67 in Swiss mouse at 20 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 83.68 % Antimalarial activity against intravenously inoculated Plasmodium yoelii N-67 in Swiss mouse at 20 mg/kg, ip on day 4 ChEMBL. 17145794
Activity (functional) = 83.68 % Antimalarial activity against intravenously inoculated Plasmodium yoelii N-67 in Swiss mouse at 20 mg/kg, ip on day 4 ChEMBL. 17145794
IC50 (functional) = 0.75 uM Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay ChEMBL. 19762125
IC50 (functional) = 0.76 uM Cytotoxicity against human A549 cells after 72 hrs by MTT assay ChEMBL. 19762125
IC50 (functional) = 0.8 uM In vitro antimalarial activity against Plasmodium falciparum ChEMBL. 10669577
IC50 (functional) = 0.8 uM Inhibitory activity against Plasmodium falciparum ChEMBL. 9357523
IC50 (functional) = 0.8 uM In vitro antimalarial activity against Plasmodium falciparum ChEMBL. 10669577
IC50 (functional) = 0.8 uM Inhibitory activity against Plasmodium falciparum ChEMBL. 9357523
IC50 (functional) = 1.98 uM Cytotoxicity against human Jurkat cells after 72 hrs by MTT assay ChEMBL. 19762125
IC50 (functional) = 3.25 uM Cytotoxicity against human CCRF-CEM cells after 72 hrs by MTT assay ChEMBL. 19762125
IC50 (functional) = 4.1 uM Cytotoxicity against human HeLa cells after 72 hrs by MTT assay ChEMBL. 19762125
IC50 (binding) = 4.37 uM Concentration required against dynamin-1 GTPase activity of sheep brain. ChEMBL. 15149689
IC50 (binding) = 4.37 uM Concentration required against dynamin-1 GTPase activity of sheep brain. ChEMBL. 15149689
IC50 (functional) = 4.5 uM Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay ChEMBL. 19762125
IC50 (ADMET) = 6.1 uM Cytotoxicity against HUVEC after 72 hrs by MTT assay ChEMBL. 23792315
IC50 (binding) = 7.69 uM Inhibition of synthetic amyloid beta42 oligomerization by ELISA ChEMBL. 17284452
IC50 (functional) = 21 uM Antimicrobial activity against Plasmodium falciparum ChEMBL. 20185316
Inhibition (binding) = 0.5 % Inhibition of synthetic amyloid beta42 fibrillization at 300 uM by ThT fluorescence analysis relative to control ChEMBL. 17284452
Inhibition (binding) = 9.8 % Inhibition of synthetic amyloid beta42 fibrillization at 30 uM by ThT fluorescence analysis relative to control ChEMBL. 17284452
Inhibition (functional) = 33.3 % Inhibition of growth of Plasmodium falcipuram NF54 ring stage at 30 uM relative to control ChEMBL. 17145794
Inhibition (functional) = 33.3 % Inhibition of growth of Plasmodium falcipuram NF54 ring stage at 30 uM relative to control ChEMBL. 17145794
Inhibition (functional) = 42 % Inhibition of phospho choline biosynthesis in Plasmodium falcipuram NF54 assessed as intracellular free choline at 10 uM ChEMBL. 17145794
Inhibition (functional) = 42 % Inhibition of phospho choline biosynthesis in Plasmodium falcipuram NF54 assessed as intracellular free choline at 10 uM ChEMBL. 17145794
Inhibition (functional) = 51 % Inhibition of growth of Plasmodium falcipuram NF54 schizont stage at 10 uM relative to control ChEMBL. 17145794
Inhibition (functional) = 51 % Inhibition of growth of Plasmodium falcipuram NF54 schizont stage at 10 uM relative to control ChEMBL. 17145794
Inhibition (ADMET) = 55.25195353 % Inhibition of sodium fluorescein uptake in OATP1B1-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM ChEMBL. 23571415
Inhibition (binding) = 57 % Inhibition of choline kinase in Plasmodium falcipuram NF54 assessed as incorporation of [methlyl-14C]choline into phosphocholine at 10 uM ChEMBL. 17145794
Inhibition (binding) = 60 % Inhibition of Plasmodium falciparum choline kinase at 100 uM ChEMBL. 17145794
Inhibition (binding) = 60 % Inhibition of Plasmodium falciparum choline kinase at 50 uM in presence of 100 uM ATP ChEMBL. 17145794
Inhibition (functional) = 62 % Inhibition of growth of Plasmodium falciparum NF54 assessed as incorporation of [3H]hypoxanthine at 10 uM relative to control ChEMBL. 17145794
Inhibition (functional) = 62 % Inhibition of growth of Plasmodium falcipuram NF54 trophozont stage at 10 uM relative to control ChEMBL. 17145794
Inhibition (functional) = 62 % Inhibition of growth of Plasmodium falciparum NF54 assessed as incorporation of [3H]hypoxanthine at 10 uM relative to control ChEMBL. 17145794
Inhibition (functional) = 62 % Inhibition of growth of Plasmodium falcipuram NF54 trophozont stage at 10 uM relative to control ChEMBL. 17145794
Inhibition (functional) = 81 % Inhibition of growth of Plasmodium falciparum NF54 assessed as incorporation of [3H]hypoxanthine at 20 uM relative to control ChEMBL. 17145794
Inhibition (functional) = 81 % Inhibition of growth of Plasmodium falciparum NF54 assessed as incorporation of [3H]hypoxanthine at 20 uM relative to control ChEMBL. 17145794
Inhibition (ADMET) = 131.1866297 % Inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells at an equimolar substrate-inhibitor concentration of 10 uM ChEMBL. 23571415
MBC (functional) = 16.9 uM Minimum bactericidal concentration against Escherichia coli ChEMBL. 15916434
MBC (functional) = 16.9 uM Minimum bactericidal concentration against Escherichia coli ChEMBL. 15916434
MBC (functional) = 18.3 uM Minimum bactericidal concentration against Shigella sonnei ChEMBL. 15916434
MBC (functional) = 18.5 uM Minimum bactericidal concentration against Enterococcus faecalis ChEMBL. 15916434
MBC (functional) = 18.9 uM Minimum bactericidal concentration against Staphylococcus aureus ChEMBL. 15916434
MBC (functional) = 63 uM Antibacterial activity against 5 x 10'5 CFU/mL Escherichia coli ATCC 25922 incubated for 72 hrs followed by growing of cells on trypticase soy agar plate for 24 hrs by CLSI M07-A8 broth microdilution method ChEMBL. 21794958
MFC (functional) = 21 uM Antifungal activity against Candida albicans CCM 8186 assessed as inhibition of colony formation after 24 hrs ChEMBL. 19762125
MIC (functional) < 2 p.p.m. Minimum inhibitory concentration of salt was tested against Staphylococcus aureus aureus at 0.1 M NaH2PO4 adjusted to pH 7.0 ChEMBL. 7381846
MIC (functional) < 2 p.p.m. Minimum inhibitory concentration of salt was tested against Bacillus subtilis at 0.1 M NaH2PO4 adjusted to pH 7.0 ChEMBL. 7381846
MIC (functional) < 2 p.p.m. Minimum inhibitory concentration of salt was tested against Streptococcus pyogenes aureus at 0.1 M NaH2PO4 adjusted to pH 7.0 ChEMBL. 7381846
MIC (functional) = 64.3 p.p.m. Minimum inhibitory concentration of salt was tested against Salmonella typhimureum aureus at 0.1 M NaH2PO4 adjusted to pH 7.0 ChEMBL. 7381846
MIC (functional) = 128.5 p.p.m. Minimum inhibitory concentration of salt was tested against Pseudomonas aeruginosa at 0.1 M NaH2PO4 adjusted to pH 7.0 ChEMBL. 7381846
MIC (functional) = 1 ug ml-1 Antibacterial activity against Escherichia coli ATCC 25922 after 12 to 18 hrs by twofold dilution method ChEMBL. 21111625
MIC (functional) = 2 ug ml-1 Ratio of MIC for Escherichia coli KAM32 harboring cloned pSP72 lmrS to MIC for Escherichia coli KAM32 harboring pSP72 ChEMBL. 20855745
MIC (functional) = 3.9 ug ml-1 Antibacterial activity against Escherichia coli KAM32 harboring pSP72 by broth microdilution method ChEMBL. 20855745
MIC (functional) = 5 ug ml-1 Minimum inhibitory concentration against Candida glabrata ChEMBL. 12127527
MIC (functional) = 7.8 ug ml-1 Antibacterial activity against Escherichia coli KAM32 harboring Staphylococcus aureus cloned pSP72 lmrS by broth microdilution method ChEMBL. 20855745
MIC (functional) = 14 uM Minimum inhibitory concentration against Candida glabrata ChEMBL. 12127527
MIC (functional) = 22 uM Antimycotic activity against Candida albicans ATCC 60193 after 48 hrs by NCCLS M-27 microdilution assay ChEMBL. 23792315
MIC (functional) = 44 uM Antimicrobial activity against Escherichia coli after 24 hrs ChEMBL. 19070403
MIC (functional) = 63 uM Antibacterial activity against 5 x 10'5 CFU/mL Escherichia coli ATCC 25922 after 72 hrs by CLSI M07-A8 broth microdilution method ChEMBL. 21794958
Potency (functional) 0.0013 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 0.5623 um PUBCHEM_BIOASSAY: qHTS Assay for Modulators of Lamin A Splicing. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 0.631 uM PubChem BioAssay. A Novel Cell-Based Assay to Identify Small Molecules for B -Galactocerebrosidase. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 1.2589 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of estrogen receptor alpha signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 2.6855 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 2.9855 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 3.1623 um PUBCHEM_BIOASSAY: qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 3.7586 uM PubChem BioAssay. A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 4.7755 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 8.0875 uM PUBCHEM_BIOASSAY: S16 Schwann cell PMP22 intronic element firefly luciferase assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 9.5205 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 10 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Fluorescence Polarization. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Assay for Enhancers of SMN2 Splice Variant Expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) 13.3322 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 15.8489 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 22.3872 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay; Stimulation with EGF. (Class of assay: confirmatory) [Related pubchem assays: 995 ] ChEMBL. No reference
Potency (functional) 22.3872 uM PUBCHEM_BIOASSAY: Inhibitors of USP1/UAF1: Pilot qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504878] ChEMBL. No reference
Potency (functional) 23.9145 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 23.9145 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.0999 uM PUBCHEM_BIOASSAY: S16 Schwann cell PMP22 intronic element beta-lactamase assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of estrogen receptor alpha signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 26.6032 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 27.306 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 28.1838 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 28.1838 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors Targeting the Menin-MLL Interaction in MLL Related Leukemias: Competition With Texas Red Labeled MLL-derived Mutant Peptide. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Inhibitors of Glutaminase (GLS). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 30.6379 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Multiplex Assay to Identify Dual Action Probes in a Cell Model of Huntington: Aggregate Formation (GFP). (Class of assay: confirmatory) [Related pubchem assays: 1482, 1471 ] ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) 31.6228 uM PUBCHEM_BIOASSAY: Inhibitors of USP1/UAF1: Pilot qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504878] ChEMBL. No reference
Potency (functional) 33.4889 uM PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 33.4889 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of the ERK Signaling Pathway using a Homogeneous Screening Assay. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 39.8107 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Fluorescence Polarization Assay for Inhibitors of MLL CXXC domain - DNA interaction. (Class of assay: confirmatory) [Related pubchem assays: 2698 (Summary assay.)] ChEMBL. No reference
Potency (functional) = 44.6684 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Bacillus subtilis Sfp phosphopantetheinyl transferase (PPTase). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of androgen receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 44.6684 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 48.9662 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 50.1187 um PUBCHEM_BIOASSAY: qHTS Assay for Identification of Novel General Anesthetics. In this assay, a GABAergic mimetic model system, apoferritin and a profluorescent 1-aminoanthracene ligand (1-AMA), was used to construct a competitive binding assay for identification of novel general anesthetics (Class of assay: confirmatory) [Related pubchem assays: 2385 (Probe Development Summary for Identification of Novel General Anesthetics), 2323 (Validation apoferritin assay run on SigmaAldrich LOPAC1280 collection)] ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of androgen receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of farnesoid X receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor delta signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of vitamin D receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of retinoid X receptor alpha signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS assay for small molecule activators of the nuclear factor-kappa B (NF-kB) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 50.1187 uM PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.941 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.941 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.941 uM PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.941 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 54.941 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 61.1306 uM PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 61.6448 uM PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 63.0957 uM PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 86.3492 uM PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] ChEMBL. No reference
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against S. aureus at pH 7.0, concentration 1031 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at P. aeruginosa at pH 7.0, concentration 1031 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at S. pyogenes at pH 7.0, concentration 1031 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at S. aureus at pH 6.0, concentration 1007 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at P. aeruginosa at pH 6.0, concentration 1007 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at S. pyogenes at pH 6.0, concentration 1007 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at S. aureus at pH 7.0, concentration 1031 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at S. aureus at pH 8.0, concentration 1042 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at P. aeruginosa at pH 8.0, concentration 1042 ppm ChEMBL. 7381846
Time (functional) = 0.5 min Sterilization time for contact germicidal efficiency (CGE) of salt was tested against at S. pyogenes at pH 8.0, concentration 1042 ppm ChEMBL. 7381846

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23 10669577
Homo sapiens ChEMBL23 19762125

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

17 literature references were collected for this gene.

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