Detailed information for compound 1125805

Basic information

Technical information
  • TDR Targets ID: 1125805
  • Name: 3-(4-methylpiperidin-1-yl)-N-phenylpropanamid e
  • MW: 246.348 | Formula: C15H22N2O
  • H donors: 1 H acceptors: 1 LogP: 2.35 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1CCN(CC1)CCC(=O)Nc1ccccc1
  • InChi: 1S/C15H22N2O/c1-13-7-10-17(11-8-13)12-9-15(18)16-14-5-3-2-4-6-14/h2-6,13H,7-12H2,1H3,(H,16,18)
  • InChiKey: BLYSKUXPYAJHOI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-(4-methyl-1-piperidyl)-N-phenyl-propanamide
  • 3-(4-methyl-1-piperidinyl)-N-phenylpropanamide
  • 3-(4-methyl-1-piperidyl)-N-phenyl-propionamide
  • 3-(4-methylpiperidin-1-yl)-N-phenyl-propanamide
  • Oprea1_481511
  • STK193345
  • MLS000709456
  • SMR000286823
  • 3-(4-Methyl-piperidin-1-yl)-N-phenyl-propionamide
  • BAS 03086439
  • Oprea1_611669

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.1193 0.2335
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0031 0.0936 0.1613
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0031 0.0036
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0894 0.1891
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.1742 0.375
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0055 0.1956 0.4219
Trypanosoma brucei GMP reductase 0.0116 0.4592 1
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0031 0.0936 0.1754
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.1956 0.4219
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0894 0.1481
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0116 0.4592 1
Trichomonas vaginalis set domain proteins, putative 0.0242 1 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0016 0.0251 0.0287
Brugia malayi RNA binding protein 0.0062 0.2265 0.2566
Brugia malayi G-protein coupled receptor 0.0055 0.1956 0.2211
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.1956 0.4219
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Mycobacterium leprae putative cytochrome p450 0.0031 0.0936 0.1577
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0894 0.1891
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0041 0.1355 0.2543
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Echinococcus granulosus tachykinin peptides receptor 99D 0.0055 0.1956 0.4219
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0031 0.0936 0.1577
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0031 0.0936 0.1577
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2265 0.4897
Onchocerca volvulus 0.0055 0.1956 0.193
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0031 0.0936 0.1754
Schistosoma mansoni opsin-like receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.1956 0.4219
Brugia malayi G-protein coupled receptor 0.0055 0.1956 0.2211
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.005 0.1742 0.1994
Echinococcus granulosus somatostatin receptor 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.1026 0.0933
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.1026 0.0933
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.1126 0.1035
Echinococcus granulosus 7TM GPCR rhodopsin 0.0055 0.1956 0.4219
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Loa Loa (eye worm) IMP dehydrogenase 1 0.0116 0.4592 0.5257
Brugia malayi larval opioid receptor 0.0055 0.1956 0.2211
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.1956 0.4219
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1863 0.374
Echinococcus multilocularis neuropeptide FF receptor 2 0.0055 0.1956 0.4219
Loa Loa (eye worm) phosphatidylinositol 3 0.0045 0.1524 0.1745
Echinococcus multilocularis dro:myosuppressin receptor 0.0055 0.1956 0.4219
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0232 0.0132
Mycobacterium ulcerans hypothetical protein 0.0053 0.1863 0.3714
Brugia malayi Dopamine receptor protein 2 0.0055 0.1956 0.2211
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Echinococcus multilocularis serotonin receptor 0.0055 0.1956 0.4219
Onchocerca volvulus 0.0055 0.1956 0.193
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0016 0.0251 0.0481
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0031 0.0936 0.1577
Brugia malayi G protein-coupled receptor 0.0055 0.1956 0.2211
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0031 0.0936 0.1754
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0707 0.0611
Loa Loa (eye worm) hypothetical protein 0.003 0.0894 0.1023
Echinococcus multilocularis tar DNA binding protein 0.0062 0.2265 0.4897
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.2265 0.2593
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0055 0.1956 0.4219
Schistosoma mansoni cytochrome P450 0.0031 0.0936 0.1982
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0031 0.0936 0.1577
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0031 0.0036
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.1355 0.1551
Loa Loa (eye worm) hypothetical protein 0.0016 0.0251 0.0287
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0232 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.1524 0.1436
Onchocerca volvulus 0.0055 0.1956 0.193
Onchocerca volvulus 0.0016 0.0251 0.022
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Schistosoma mansoni opsin-like receptor 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0031 0.0936 0.1754
Schistosoma mansoni myosin xvIII 0.0055 0.1956 0.4219
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0055 0.1956 0.2239
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1863 0.374
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.1956 0.4219
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1863 0.2104
Brugia malayi neuropeptide F receptor 0.0055 0.1956 0.2211
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0031 0.0936 0.1754
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0742 0.0646
Schistosoma mansoni hypothetical protein 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.004 0.1286 0.1472
Mycobacterium ulcerans inosine 5-monophosphate dehydrogenase 0.0051 0.1795 0.3557
Schistosoma mansoni flap endonuclease-1 0.0024 0.0599 0.1243
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0016 0.0251 0.021
Plasmodium vivax inosine-5'-monophosphate dehydrogenase, putative 0.0116 0.4592 1
Trypanosoma cruzi target of rapamycin kinase 3 0.0036 0.1128 0.2054
Echinococcus multilocularis 0.0031 0.0936 0.1982
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.1863 0.3714
Brugia malayi Cytochrome P450 family protein 0.0116 0.4588 0.5236
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.005 0.1742 0.375
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0053 0.1863 0.3714
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0055 0.1956 0.4219
Schistosoma mansoni opsin-like receptor 0.0055 0.1956 0.4219
Brugia malayi cytochrome P450 0.0031 0.0936 0.1039
Echinococcus multilocularis allatostatin A receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Leishmania major inosine-5-monophosphate dehydrogenase 0.0116 0.4592 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0045 0.1524 0.2962
Echinococcus granulosus neuropeptide s receptor 0.0055 0.1956 0.4219
Echinococcus granulosus serotonin receptor 0.0055 0.1956 0.4219
Onchocerca volvulus 0.0055 0.1956 0.193
Schistosoma mansoni hypothetical protein 0.0055 0.1956 0.4219
Brugia malayi putative neuropeptide receptor 0.0055 0.1956 0.2211
Loa Loa (eye worm) CYP4Cod1 0.0041 0.1355 0.1551
Echinococcus granulosus neuropeptide receptor 0.0055 0.1956 0.4219
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0031 0.0936 0.1754
Toxoplasma gondii IMP dehydrogenas 0.0116 0.4592 1
Echinococcus granulosus allatostatin A receptor 0.0055 0.1956 0.4219
Brugia malayi sulfakinin receptor protein 0.0055 0.1956 0.2211
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Brugia malayi Melatonin receptor type 1A 0.0055 0.1956 0.2211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.1026 0.0933
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0251 0.021
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0053 0.1863 0.3714
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0031 0.0036
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0031 0.0936 0.1577
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0031 0.0936 0.1577
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.073 0.0635
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0232 0.0441
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0031 0.0936 0.1613
Schistosoma mansoni biogenic amine (5HT) receptor 0.0055 0.1956 0.4219
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.1956 0.4219
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.1524 0.1436
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0894 0.1891
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0036
Onchocerca volvulus 0.0055 0.1956 0.193
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.1742 0.375
Plasmodium vivax acyl-CoA synthetase, putative 0.004 0.1286 0.2385
Echinococcus granulosus inosine 5' monophosphate dehydrogenase 2 0.0116 0.4592 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.1126 0.1035
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0884 0.079
Onchocerca volvulus 0.0055 0.1956 0.193
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0232 0.0231
Plasmodium falciparum inosine-5'-monophosphate dehydrogenase 0.0116 0.4592 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0894 0.1891
Trichomonas vaginalis PIKK family atypical protein kinase 0.0045 0.1524 0.1436
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0016 0.0251 0.0042
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.1355 0.2575
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0045 0.1524 0.3272
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0251 0.021
Loa Loa (eye worm) hypothetical protein 0.0053 0.1863 0.2133
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0045 0.1524 0.2962
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0031 0.0936 0.1754
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0251 0.0252
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB3 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0065 0.2378 0.5007
Giardia lamblia GTOR 0.0045 0.1524 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2265 0.4897
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0031 0.0936 0.1754
Echinococcus granulosus g protein coupled receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0055 0.1956 0.2239
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0053 0.1863 0.3714
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Brugia malayi ORL1-like opioid receptor 0.0055 0.1956 0.2211
Brugia malayi Cytochrome P450 family protein 0.0041 0.1355 0.1521
Entamoeba histolytica acyl-coA synthetase, putative 0.0053 0.1863 1
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0036
Onchocerca volvulus 0.0055 0.1956 0.193
Echinococcus granulosus neuropeptides capa receptor 0.0055 0.1956 0.4219
Schistosoma mansoni amine GPCR 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0251 0.0252
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0031 0.0936 0.1613
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0894 0.1891
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.1956 0.4219
Plasmodium vivax SET domain protein, putative 0.003 0.0894 0.1481
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0019 0.0388 0.0357
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.1956 0.2239
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0031 0.0936 0.1754
Echinococcus multilocularis serotonin receptor 0.0055 0.1956 0.4219
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0031 0.0936 0.1577
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0036
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2265 0.4897
Brugia malayi Pre-SET motif family protein 0.0212 0.8735 1
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0031 0.0936 0.1754
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Onchocerca volvulus Putative GMP reductase 0.0051 0.1795 0.1769
Echinococcus granulosus biogenic amine 5HT receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis inosine 5' monophosphate dehydrogenase 2 0.0116 0.4592 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0055 0.1956 0.2211
Echinococcus granulosus orexin receptor type 2 0.0055 0.1956 0.4219
Echinococcus multilocularis neuropeptides capa receptor 0.0055 0.1956 0.4219
Schistosoma mansoni acetyl-CoA synthetase 0.0016 0.0251 0.0481
Echinococcus granulosus flap endonuclease 1 0.0026 0.0707 0.1481
Echinococcus multilocularis neuropeptide receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0055 0.1956 0.4219
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.1956 0.2239
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0055 0.1956 0.4219
Brugia malayi Cytochrome P450 family protein 0.0041 0.1355 0.1521
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Trichomonas vaginalis antibiotic synthetase, putative 0.0016 0.0251 0.015
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0031 0.0036
Onchocerca volvulus 0.0016 0.0251 0.022
Onchocerca volvulus 0.0055 0.1956 0.193
Trypanosoma cruzi GMP reductase 0.0116 0.4592 1
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0031 0.0936 0.1577
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0845 0.1785
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0031 0.0936 0.1754
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2265 0.4897
Brugia malayi Cytochrome P450 family protein 0.0031 0.0936 0.1039
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Mycobacterium ulcerans inosine 5'-monophosphate dehydrogenase 0.0116 0.4592 1
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0031 0.0936 0.1613
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0894 0.1891
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.063 0.0533
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0055 0.1956 0.4219
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0055 0.1956 0.4219
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.8735 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0039 0.124 0.1149
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0055 0.1956 0.4219
Trichomonas vaginalis antibiotic synthetase, putative 0.0016 0.0251 0.015
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0251 0.0042
Brugia malayi AKH receptor 0.0055 0.1956 0.2211
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0251 0.0252
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.1863 0.3714
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.1126 0.1035
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) G-protein coupled receptor 0.0055 0.1956 0.2239
Echinococcus granulosus tar DNA binding protein 0.0062 0.2265 0.4897
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0116 0.4592 1
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0031 0.0936 0.1577
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0031 0.0936 0.1577
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Schistosoma mansoni neuropeptide receptor 0.0055 0.1956 0.4219
Leishmania major cytochrome p450-like protein 0.0031 0.0936 0.1613
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0232 0.0266
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0628 0.0532
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0628 0.0532
Leishmania major acetyl-CoA synthetase, putative 0.0016 0.0251 0.0042
Loa Loa (eye worm) hypothetical protein 0.004 0.1286 0.1472
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0031 0.0936 0.1577
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0036
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0045 0.1524 0.7896
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.063 0.0533
Brugia malayi Pre-SET motif family protein 0.003 0.0894 0.0991
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Schistosoma mansoni amine GPCR 0.0055 0.1956 0.4219
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0055 0.1956 0.2211
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0707 0.105
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0036
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0707 0.0809
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1863 0.3714
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0031 0.0936 0.1754
Brugia malayi TAR-binding protein 0.0062 0.2265 0.2566
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0232 0.0132
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0707 0.1088
Schistosoma mansoni hypothetical protein 0.0055 0.1956 0.4219
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.004 0.1286 0.5
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0055 0.1956 0.4219
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0707 0.1481
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.005 0.1742 0.1965
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0031 0.0936 0.1577
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.063 0.0533
Brugia malayi putative neuropeptide receptor NPR1 0.0055 0.1956 0.2211
Schistosoma mansoni biogenic amine receptor 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.073 0.0635
Schistosoma mansoni amine GPCR 0.0055 0.1956 0.4219
Schistosoma mansoni amine GPCR 0.0055 0.1956 0.4219
Schistosoma mansoni neuropeptide F-like receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0055 0.1956 0.4219
Brugia malayi GMP reductase 0.0051 0.1795 0.2026
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) neuropeptide F receptor 0.0055 0.1956 0.2239
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0707 0.105
Schistosoma mansoni hypothetical protein 0.0031 0.0936 0.1982
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.1193 0.2335
Brugia malayi neuropeptide F receptor 0.0055 0.1956 0.2211
Onchocerca volvulus 0.0016 0.0251 0.022
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.1026 0.0933
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.063 0.0533
Schistosoma mansoni adenoreceptor 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.004 0.1286 0.2545
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0031 0.0036
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0251 0.021
Echinococcus granulosus g-protein coupled receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0031 0.0036
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0016 0.0251 0.021
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1863 0.3714
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0031 0.0936 0.1754
Onchocerca volvulus 0.0055 0.1956 0.193
Schistosoma mansoni neuropeptide f receptor 76f 0.0055 0.1956 0.4219
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis G-protein coupled receptor, putative 0.0055 0.1956 0.4219
Echinococcus multilocularis orexin receptor type 2 0.0055 0.1956 0.4219
Schistosoma mansoni neuropeptide receptor 0.0055 0.1956 0.4219
Plasmodium falciparum flap endonuclease 1 0.0026 0.0707 0.105
Onchocerca volvulus 0.003 0.0894 0.0865
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0031 0.0936 0.1577
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.2265 0.2566
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0031 0.0936 0.1577
Onchocerca volvulus 0.0055 0.1956 0.193
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0031 0.0936 0.1577
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0031 0.0936 0.1577
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0055 0.1956 0.4219
Echinococcus granulosus dro:myosuppressin receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis sex peptide receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) oxidoreductase 0.0016 0.0251 0.0287
Schistosoma mansoni amine GPCR 0.0055 0.1956 0.4219
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.1956 0.4219
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Trypanosoma brucei inosine-5'-monophosphate dehydrogenase 0.0116 0.4592 1
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0045 0.1524 0.2962
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0055 0.1956 0.2239
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.1863 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0055 0.1956 0.2211
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0036
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0051 0.1795 0.2026
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0251 0.0042
Onchocerca volvulus 0.0053 0.1863 0.1837
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0031 0.0936 0.1613
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0707 0.1088
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0232 0.0132
Trypanosoma cruzi GMP reductase 0.0116 0.4592 1
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1863 0.2104
Schistosoma mansoni neuropeptide receptor 0.0055 0.1956 0.4219
Echinococcus granulosus alpha 1A adrenergic receptor 0.0055 0.1956 0.4219
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0031 0.0936 0.1754
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0053 0.1863 0.3714
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0055 0.1956 0.2239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.1026 0.0933
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Schistosoma mansoni histamine h1 receptor 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.1193 0.2335
Mycobacterium leprae PROBABLE INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE GUAB1(IMP DEHYDROGENASE) (IMPDH) (IMPD) 0.0051 0.1795 0.3557
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0031 0.0936 0.1577
Trypanosoma cruzi cytochrome P450, putative 0.0041 0.1355 0.2575
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.1126 0.1035
Brugia malayi inosine-5'-monophosphate dehydrogenase 0.0051 0.1795 0.2026
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.1026 0.0933
Brugia malayi Tachykinin-like peptides receptor 99D 0.0055 0.1956 0.2211
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0031 0.0936 0.1754
Echinococcus multilocularis g-protein coupled receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0016 0.0251 0.0287
Brugia malayi Dopamine receptor 0.0055 0.1956 0.2211
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Entamoeba histolytica acyl-CoA synthetase, putative 0.0053 0.1863 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Leishmania major guanosine monophosphate reductase 0.0116 0.4592 1
Brugia malayi Serotonin receptor 0.0055 0.1956 0.2211
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Brugia malayi Serotonin receptor 0.0055 0.1956 0.2211
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0016 0.0251 0.0042
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0031 0.0936 0.1754
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0116 0.4592 1
Loa Loa (eye worm) hypothetical protein 0.004 0.1286 0.1472
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0031 0.0036
Onchocerca volvulus 0.0055 0.1956 0.193
Brugia malayi inosine-5'-monophosphate dehydrogenase family protein 0.0116 0.4592 0.524
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0016 0.0251 0.0481
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0016 0.0251 0.0252
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) TYRA-2 protein 0.0055 0.1956 0.2239
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0251 0.0042
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1742 0.375
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0055 0.1956 0.193
Brugia malayi AMP-binding enzyme family protein 0.0053 0.1863 0.2104
Plasmodium falciparum acyl-CoA synthetase 0.004 0.1286 0.2385
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0045 0.1524 0.3272
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0055 0.1956 0.2239
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0055 0.1956 0.2211
Loa Loa (eye worm) RNA binding protein 0.0062 0.2265 0.2593
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) GMP reductase 0.0051 0.1795 0.2055
Echinococcus granulosus g protein coupled receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Echinococcus granulosus tm gpcr rhodopsin 0.0055 0.1956 0.4219
Leishmania major cytochrome p450-like protein 0.0041 0.1355 0.2575
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0045 0.1524 0.7896
Wolbachia endosymbiont of Brugia malayi IMP dehydrogenase 0.0116 0.4592 0.5
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Echinococcus multilocularis neuropeptide receptor A26 0.0055 0.1956 0.4219
Loa Loa (eye worm) cytochrome P450 0.0031 0.0936 0.1071
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0016 0.0251 0.021
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0034 0.1026 0.0933
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0031 0.0936 0.1754
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Schistosoma mansoni biogenic amine receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Echinococcus multilocularis g protein coupled receptor 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0016 0.0251 0.021
Echinococcus granulosus 7tm_1 domain containing protein 0.0055 0.1956 0.4219
Trypanosoma brucei cytochrome P450, putative 0.0041 0.1355 0.2575
Brugia malayi hypothetical protein 0.0055 0.1956 0.2211
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0053 0.1863 0.3846
Echinococcus granulosus g protein coupled receptor 0.0055 0.1956 0.4219
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0232 0.0441
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0707 0.2828
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0045 0.1524 0.2962
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0037 0.1193 0.2335
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0055 0.1956 0.2211
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Schistosoma mansoni tar DNA-binding protein 0.0062 0.2265 0.4897
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0031 0.0936 0.1754
Trypanosoma cruzi inosine-5'-monophosphate dehydrogenase, putative 0.0116 0.4592 1
Echinococcus granulosus G protein coupled receptor 139 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) cytochrome P450 family protein 0.0116 0.4588 0.5253
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.005 0.1742 0.375
Echinococcus multilocularis fmrfamide receptor 0.0055 0.1956 0.4219
Schistosoma mansoni inosine-5-monophosphate dehydrogenase 0.0116 0.4592 1
Toxoplasma gondii cytochrome p450 superfamily protein 0.0031 0.0936 0.1577
Echinococcus granulosus neuropeptide Y receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Leishmania major 4-coumarate:coa ligase-like protein 0.0053 0.1863 0.374
Loa Loa (eye worm) hypothetical protein 0.001 0.0031 0.0036
Loa Loa (eye worm) melatonin receptor type 1A 0.0055 0.1956 0.2239
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.05 0.0613
Echinococcus granulosus neuropeptide receptor A26 0.0055 0.1956 0.4219
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0045 0.1524 0.2962
Onchocerca volvulus 0.0055 0.1956 0.193
Echinococcus granulosus peptide allatostatin:somatostatin 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.004 0.1286 0.1472
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0055 0.1956 0.2211
Leishmania major cytochrome p450-like protein 0.0031 0.0936 0.1613
Mycobacterium ulcerans acyl-CoA synthetase 0.0053 0.1863 0.3714
Echinococcus granulosus hypothetical protein 0.0055 0.1956 0.4219
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0016 0.0251 0.0042
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0742 0.0646
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0016 0.0251 0.0042
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0045 0.1524 0.3272
Echinococcus granulosus neuropeptide receptor 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0031 0.0936 0.1754
Onchocerca volvulus 0.0055 0.1956 0.193
Loa Loa (eye worm) TAR-binding protein 0.0062 0.2265 0.2593
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0232 0.0441
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1742 0.375
Onchocerca volvulus 0.0055 0.1956 0.193
Onchocerca volvulus 0.0055 0.1956 0.193
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0031 0.0936 0.1577
Brugia malayi GnHR receptor homolog 0.0055 0.1956 0.2211
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Brugia malayi RE15519p 0.0055 0.1956 0.2211
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) hypothetical protein 0.0053 0.1863 0.2133
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.004 0.1286 0.1472
Brugia malayi AMP-binding enzyme family protein 0.0016 0.0251 0.0252
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0016 0.0251 0.021
Echinococcus granulosus rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Echinococcus granulosus neuropeptide FF receptor 2 0.0055 0.1956 0.4219
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0031 0.0936 0.1577
Echinococcus granulosus cytochrome P450 2K1 0.0031 0.0936 0.1982
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0036 0.1128 0.2054
Onchocerca volvulus 0.0055 0.1956 0.193
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0232 0.0132
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0045 0.1524 0.1715
Schistosoma mansoni alpha-1 adrenergic receptor 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0016 0.0251 0.021
Echinococcus multilocularis fmrfamide receptor 0.0055 0.1956 0.4219
Trichomonas vaginalis PIKK family atypical protein kinase 0.0036 0.1126 0.1035
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0036 0.1128 0.2054
Echinococcus granulosus fmrfamide receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0053 0.1863 0.3846
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0016 0.0251 0.021
Brugia malayi follicle stimulating hormone receptor 0.0055 0.1956 0.2211
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB3 (IMP dehydrogenase 2) (inosinic acid dehydrogenase) (inosinate dehydrogena 0.0065 0.2378 0.49
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0055 0.1956 0.4219
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Mycobacterium tuberculosis Probable inosine-5'-monophosphate dehydrogenase GuaB2 (imp dehydrogenase) (inosinic acid dehydrogenase) (inosinate dehydrogenase 0.0116 0.4592 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Leishmania major acetyl-CoA synthetase, putative 0.0016 0.0251 0.0042
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0031 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0027 0.0742 0.0646
Echinococcus multilocularis g protein coupled receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis g protein coupled receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis neuropeptide Y receptor 0.0055 0.1956 0.4219
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0707 0.1088
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0016 0.0251 0.0287
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0031 0.0936 0.1577
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0055 0.1956 0.4219
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.005 0.1742 0.375
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Schistosoma mansoni hypothetical protein 0.0055 0.1956 0.4219
Schistosoma mansoni growth hormone secretagogue receptor 0.0055 0.1956 0.4219
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0031 0.0936 0.1754
Echinococcus multilocularis rhodopsin orphan GPCR 0.0055 0.1956 0.4219
Schistosoma mansoni neuropeptide receptor 0.0055 0.1956 0.4219
Onchocerca volvulus 0.0016 0.0251 0.022
Schistosoma mansoni biogenic amine receptor 0.0055 0.1956 0.4219
Mycobacterium leprae Probable inosine-5'-monophosphate dehydrogenase GuaB2 (IMP dehydrogenase) (IMPDH) (IMPD) 0.0116 0.4592 1
Loa Loa (eye worm) hypothetical protein 0.0053 0.1863 0.2133
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0842 0.0748
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0016 0.0251 0.0252
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0016 0.0251 0.021
Mycobacterium ulcerans fatty-acid-CoA ligase 0.004 0.1286 0.2385
Brugia malayi Flap endonuclease-1 0.0026 0.0707 0.0776
Loa Loa (eye worm) cytochrome P450 family protein 0.0041 0.1355 0.1551
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0055 0.1956 0.4219
Echinococcus multilocularis somatostatin receptor 0.0055 0.1956 0.4219
Mycobacterium leprae Conserved hypothetical protein 0.0031 0.0936 0.1577
Loa Loa (eye worm) hypothetical protein 0.0055 0.1956 0.2239
Onchocerca volvulus 0.0055 0.1956 0.193
Onchocerca volvulus Neuropeptide F receptor homolog 0.0055 0.1956 0.193
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0894 0.1891
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0628 0.0532
Echinococcus multilocularis neuropeptide receptor 0.0055 0.1956 0.4219
Echinococcus multilocularis G protein coupled receptor 139 0.0055 0.1956 0.4219
Brugia malayi Dopamine receptor protein 1 0.0055 0.1956 0.2211
Toxoplasma gondii target of rapamycin (TOR), putative 0.0034 0.1026 0.1785
Echinococcus multilocularis neuropeptide s receptor 0.0055 0.1956 0.4219
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0055 0.1956 0.4219
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0045 0.1524 0.2962
Echinococcus granulosus sex peptide receptor 0.0055 0.1956 0.4219

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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