Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0397 | 0.0769 | 0.516 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0023 | 0.0017 | 0.0017 |
Brugia malayi | nuclear receptor RXR | 0.0018 | 0.0007 | 0.0044 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0007 | 0.0044 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0023 | 0.0017 | 0.0641 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0034 | 0.0039 | 0.0246 |
Brugia malayi | tailless protein | 0.0016 | 0.0003 | 0.0019 |
Schistosoma mansoni | coup transcription factor | 0.0034 | 0.0039 | 0.0246 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0016 | 0.0003 | 0.0019 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0099 | 0.017 | 0.8837 |
Echinococcus granulosus | mothers against decapentaplegic 2 | 0.0023 | 0.0018 | 0.011 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0034 | 0.0039 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Toxoplasma gondii | ABC1 family protein | 0.011 | 0.0192 | 0.0258 |
Leishmania major | DNA polymerase eta, putative | 0.002 | 0.0013 | 0.04 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.004 | 0.0051 | 0.246 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0034 | 0.0039 | 0.0258 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0029 | 0.0029 | 0.0627 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.025 | 0.0474 | 0.342 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0034 | 0.0039 | 0.0258 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0048 | 0.1344 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0258 |
Echinococcus granulosus | ubiquitin carboxyl terminal hydrolase 8 | 0.004 | 0.0051 | 0.0322 |
Echinococcus granulosus | Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 | 0.004 | 0.0051 | 0.0322 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0093 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0034 | 0.0039 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0026 | 0.017 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0058 | 0.0089 | 0.059 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0099 | 0.0171 | 0.017 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0016 | 0.0003 | 0.0018 |
Trypanosoma brucei | trypanothione reductase | 0.0099 | 0.017 | 0.8869 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0099 | 0.017 | 0.1138 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0034 | 0.0039 | 0.0258 |
Brugia malayi | MH2 domain containing protein | 0.0023 | 0.0018 | 0.0115 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0048 | 0.9136 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0058 | 0.0089 | 0.059 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0029 | 0.0189 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0034 | 0.0039 | 0.0246 |
Schistosoma mansoni | DNA polymerase eta | 0.002 | 0.0013 | 0.0077 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0093 | 0.0776 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0017 | 0.0006 | 0.0035 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.002 | 0.0013 | 0.04 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0034 | 0.0039 | 0.0038 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.002 | 0.0013 | 0.04 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.002 | 0.0013 | 0.0054 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.011 | 0.0192 | 0.0191 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0052 | 0.0075 | 0.0501 |
Mycobacterium ulcerans | hypothetical protein | 0.011 | 0.0192 | 0.1738 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0312 | 0.0599 | 0.4018 |
Mycobacterium leprae | Probable lipase LipE | 0.011 | 0.0192 | 0.3649 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.0273 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0668 | 0.1313 | 0.1313 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0023 | 0.0017 | 0.0044 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0034 | 0.0039 | 0.0258 |
Mycobacterium ulcerans | lipase LipD | 0.011 | 0.0192 | 0.1738 |
Echinococcus granulosus | ubiquitin specific protease 41 | 0.004 | 0.0051 | 0.0322 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0052 | 0.0075 | 0.0475 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0034 | 0.004 | 1 |
Echinococcus multilocularis | neuropeptide receptor | 0.0487 | 0.0948 | 0.0948 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0034 | 0.0039 | 0.0246 |
Onchocerca volvulus | 0.011 | 0.0192 | 0.6518 | |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0031 | 0.0034 | 0.0226 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0016 | 0.0003 | 0.0003 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0029 | 0.0029 | 0.0159 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0016 | 0.0003 | 0.0019 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0225 | 0.0424 | 0.3052 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0016 | 0.0003 | 0.0018 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0034 | 0.004 | 0.2106 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0025 | 0.0022 | 0.0144 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0034 | 0.0039 | 0.0258 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0034 | 0.004 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0034 | 0.0039 | 0.1313 |
Schistosoma mansoni | smad | 0.0023 | 0.0018 | 0.011 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0016 | 0.0003 | 0.0095 |
Brugia malayi | MH2 domain containing protein | 0.0052 | 0.0075 | 0.0499 |
Mycobacterium tuberculosis | Possible conserved lipoprotein LpqK | 0.011 | 0.0192 | 0.1358 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0258 |
Schistosoma mansoni | cpg binding protein | 0.0059 | 0.009 | 0.057 |
Schistosoma mansoni | ap endonuclease | 0.0023 | 0.0017 | 0.0106 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0023 | 0.0017 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.0794 | 0.1566 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0029 | 0.0191 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.011 | 0.0192 | 0.1219 |
Schistosoma mansoni | tar DNA-binding protein | 0.0397 | 0.0769 | 0.4906 |
Brugia malayi | hypothetical protein | 0.0253 | 0.048 | 0.3219 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.0246 | 0.1568 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0016 | 0.0003 | 0.0019 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0034 | 0.0039 | 0.0258 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0093 | 0.0587 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0258 |
Plasmodium falciparum | glutathione reductase | 0.0034 | 0.004 | 0.2129 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0141 | 0.0254 | 0.1619 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0007 | 0.0044 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0253 | 0.048 | 0.3061 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.04 |
Brugia malayi | beta-lactamase | 0.011 | 0.0192 | 0.1282 |
Toxoplasma gondii | thioredoxin reductase | 0.0099 | 0.017 | 0.0228 |
Brugia malayi | nuclear receptor NHR-88 | 0.0034 | 0.0039 | 0.0258 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0021 | 0.0015 | 0.0499 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.002 | 0.0013 | 0.0077 |
Echinococcus multilocularis | dna polymerase eta | 0.002 | 0.0013 | 0.0012 |
Brugia malayi | beta-lactamase family protein | 0.011 | 0.0192 | 0.1282 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0034 | 0.004 | 0.0268 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0099 | 0.017 | 0.12 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.002 | 0.0013 | 0.0054 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0013 | 0.0077 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0034 | 0.004 | 0.1882 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0034 | 0.004 | 0.0048 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.0003 | 0.0019 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0034 | 0.0039 | 0.0258 |
Brugia malayi | conserved hypotetical protein | 0.0016 | 0.0003 | 0.0019 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0034 | 0.0039 | 0.1313 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0016 | 0.0003 | 0.0019 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0029 | 0.0191 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0016 | 0.0003 | 0.0003 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0034 | 0.0039 | 0.0246 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0041 | 0.0055 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 0.0222 | 0.1416 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0034 | 0.004 | 0.004 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0021 | 0.0015 | 0.0564 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0034 | 0.0039 | 0.0246 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0023 | 0.0017 | 0.0044 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.002 | 0.0013 | 0.0666 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0013 | 0.0081 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0018 | 0.0115 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0034 | 0.004 | 0.2106 |
Schistosoma mansoni | nuclear receptor | 0.0016 | 0.0003 | 0.0018 |
Loa Loa (eye worm) | glutaminase 2 | 0.0533 | 0.1041 | 0.6992 |
Loa Loa (eye worm) | DR-78 | 0.0016 | 0.0003 | 0.0019 |
Brugia malayi | intermediate filament protein | 0.0058 | 0.0089 | 0.059 |
Schistosoma mansoni | cpg binding protein | 0.0059 | 0.009 | 0.057 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Echinococcus multilocularis | GPCR, family 2 | 0.0099 | 0.017 | 0.0169 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0016 | 0.0003 | 0.0018 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0012 | 0.0051 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0034 | 0.0039 | 0.0258 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.004 | 0.0051 | 0.0373 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0016 | 0.0003 | 0.0018 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0034 | 0.004 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0052 | 0.0075 | 0.0499 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0099 | 0.017 | 0.0169 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0029 | 0.0029 | 0.1278 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0225 | 0.0424 | 0.3052 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0192 | 0.1282 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0034 | 0.0039 | 0.1313 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0192 | 0.1282 |
Brugia malayi | MH2 domain containing protein | 0.0756 | 0.1489 | 1 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0052 | 0.0075 | 0.0074 |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0192 | 0.1358 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0099 | 0.017 | 0.1082 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0258 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0034 | 0.0039 | 0.0246 |
Brugia malayi | MH1 domain containing protein | 0.0028 | 0.0029 | 0.0189 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.07 | 0.1377 | 1 |
Echinococcus granulosus | Smad4 | 0.0052 | 0.0075 | 0.0475 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0093 | 0.0776 |
Echinococcus multilocularis | cpg binding protein | 0.0059 | 0.009 | 0.0089 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0034 | 0.004 | 0.2129 |
Brugia malayi | Thioredoxin reductase | 0.0099 | 0.017 | 0.1137 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0034 | 0.0039 | 0.0246 |
Schistosoma mansoni | smad1 5 8 and | 0.0052 | 0.0075 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0013 | 0.0081 |
Schistosoma mansoni | Smad4 | 0.0052 | 0.0075 | 0.0475 |
Schistosoma mansoni | ubiquitin-specific peptidase 8 (C19 family) | 0.004 | 0.0051 | 0.0322 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0034 | 0.0039 | 0.0246 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0225 | 0.0424 | 0.8867 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.025 | 0.0474 | 0.342 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0034 | 0.004 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0093 |
Onchocerca volvulus | 0.0029 | 0.0029 | 0.097 | |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0041 | 0.0055 | 0.0068 |
Echinococcus multilocularis | mothers against decapentaplegic 2 | 0.0023 | 0.0018 | 0.0017 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0016 | 0.0003 | 0.0019 |
Loa Loa (eye worm) | TAR-binding protein | 0.0397 | 0.0769 | 0.516 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0109 | 0.0191 | 0.0256 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0026 | 0.017 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0756 | 0.1489 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0034 | 0.004 | 0.0268 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Onchocerca volvulus | 0.016 | 0.0293 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0029 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.017 | 0.1138 |
Trichomonas vaginalis | conserved hypothetical protein | 0.004 | 0.0051 | 0.0373 |
Schistosoma mansoni | glutaminase | 0.0533 | 0.1041 | 0.6649 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0016 | 0.0003 | 0.0018 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0034 | 0.004 | 0.0253 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.017 | 0.1082 |
Echinococcus multilocularis | Smad4 | 0.0052 | 0.0075 | 0.0074 |
Plasmodium vivax | hypothetical protein, conserved | 0.011 | 0.0192 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0034 | 0.0039 | 0.0246 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0099 | 0.017 | 0.1138 |
Schistosoma mansoni | nuclear hormone receptor | 0.0034 | 0.0039 | 0.0246 |
Brugia malayi | nuclear hormone receptor | 0.0034 | 0.0039 | 0.0258 |
Trypanosoma brucei | isocitrate dehydrogenase, putative | 0.0017 | 0.0005 | 0.0277 |
Schistosoma mansoni | cpg binding protein | 0.0056 | 0.0084 | 0.053 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0023 | 0.0017 | 0.0172 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0192 | 0.1738 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Treponema pallidum | NADH oxidase | 0.0034 | 0.004 | 1 |
Giardia lamblia | Ubiquitin carboxyl-terminal hydrolase 4 | 0.004 | 0.0051 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.011 | 0.0192 | 0.1219 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.002 | 0.0013 | 0.0077 |
Echinococcus granulosus | GPCR family 2 | 0.0099 | 0.017 | 0.1082 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0016 | 0.0003 | 0.0018 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0017 | 0.0006 | 0.0036 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0034 | 0.004 | 0.2106 |
Schistosoma mansoni | tar DNA-binding protein | 0.0397 | 0.0769 | 0.4906 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.04 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0034 | 0.004 | 0.0253 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0052 | 0.0075 | 0.0074 |
Schistosoma mansoni | Smad4 | 0.0023 | 0.0018 | 0.011 |
Brugia malayi | glutathione reductase | 0.0099 | 0.017 | 0.1137 |
Brugia malayi | ecdysone receptor | 0.0016 | 0.0003 | 0.0019 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0041 | 0.0055 | 0.2653 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0018 | 0.0007 | 0.0044 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0034 | 0.0039 | 0.0258 |
Echinococcus granulosus | dnaJ subfamily B | 0.0794 | 0.1566 | 1 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0034 | 0.004 | 0.2129 |
Schistosoma mansoni | smad1 5 8 and | 0.0052 | 0.0075 | 0.0475 |
Toxoplasma gondii | 1,3-beta-glucan synthase component protein | 0.3619 | 0.7236 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.011 | 0.0192 | 1 |
Brugia malayi | Ubiquitin carboxyl-terminal hydrolase family protein | 0.004 | 0.0051 | 0.0339 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0034 | 0.0039 | 0.0246 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0041 | 0.0055 | 0.0408 |
Mycobacterium tuberculosis | Probable hydrolase | 0.011 | 0.0192 | 0.1358 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0013 | 0.0666 |
Mycobacterium ulcerans | hypothetical protein | 0.0029 | 0.0029 | 0.0159 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0018 | 0.0007 | 0.0042 |
Leishmania major | hypothetical protein, conserved | 0.011 | 0.0192 | 1 |
Loa Loa (eye worm) | glutaminase | 0.0533 | 0.1041 | 0.6992 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0192 | 0.1282 |
Brugia malayi | nuclear hormone receptor | 0.0016 | 0.0003 | 0.0019 |
Brugia malayi | MH1 domain containing protein | 0.0052 | 0.0075 | 0.0499 |
Echinococcus granulosus | dna polymerase eta | 0.002 | 0.0013 | 0.0077 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0034 | 0.0039 | 0.0246 |
Echinococcus multilocularis | tar DNA binding protein | 0.0397 | 0.0769 | 0.0768 |
Echinococcus granulosus | FTZ F1 alpha | 0.0034 | 0.0039 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0007 | 0.0044 |
Schistosoma mansoni | hypothetical protein | 0.0214 | 0.04 | 0.2553 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0034 | 0.004 | 0.0268 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.0016 | 0.0003 | 0.0095 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0034 | 0.0039 | 0.0246 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0048 | 0.2582 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0052 | 0.0075 | 0.0499 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0016 | 0.0003 | 0.0019 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0034 | 0.004 | 0.0268 |
Mycobacterium tuberculosis | Probable conserved lipoprotein | 0.011 | 0.0192 | 0.1358 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0029 | 0.0029 | 0.0174 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0016 | 0.0003 | 0.0019 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0125 | 0.0222 | 0.1416 |
Loa Loa (eye worm) | hypothetical protein | 0.0253 | 0.048 | 0.3219 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.0334 | 0.2237 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0225 | 0.0424 | 0.3052 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0192 | 0.1282 |
Leishmania major | ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative | 0.004 | 0.0051 | 0.246 |
Loa Loa (eye worm) | hypothetical protein | 0.0312 | 0.0599 | 0.4018 |
Echinococcus granulosus | cpg binding protein | 0.0059 | 0.009 | 0.057 |
Schistosoma mansoni | nuclear hormone receptor | 0.0016 | 0.0003 | 0.0018 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0034 | 0.004 | 0.0048 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0075 | 0.0477 |
Onchocerca volvulus | 0.0052 | 0.0075 | 0.2548 | |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0141 | 0.0254 | 0.0253 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.017 | 0.1082 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0018 | 0.0007 | 0.0042 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.011 | 0.0192 | 0.1282 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0023 | 0.0018 | 0.0115 |
Leishmania major | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.04 |
Schistosoma mansoni | tar DNA-binding protein | 0.0397 | 0.0769 | 0.4906 |
Echinococcus multilocularis | geminin | 0.054 | 0.1055 | 0.1055 |
Echinococcus granulosus | mothers against decapentaplegic 6 | 0.0023 | 0.0018 | 0.011 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0052 | 0.0075 | 0.0475 |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0192 | 0.1358 |
Mycobacterium tuberculosis | Conserved protein | 0.011 | 0.0192 | 0.1358 |
Echinococcus multilocularis | ubiquitin specific protease 41 | 0.004 | 0.0051 | 0.005 |
Brugia malayi | ecdysteroid receptor | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0051 | 0.0339 |
Brugia malayi | Isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0031 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0034 | 0.0039 | 0.0258 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0005 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0029 | 0.0029 | 0.0159 |
Brugia malayi | isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0031 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0034 | 0.0039 | 0.0246 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0794 | 0.1566 | 0.1565 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.011 | 0.0192 | 0.1738 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0029 | 0.0029 | 0.1278 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0034 | 0.004 | 0.0266 |
Onchocerca volvulus | 0.011 | 0.0192 | 0.6518 | |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0253 | 0.048 | 0.0479 |
Schistosoma mansoni | lamin | 0.0058 | 0.0089 | 0.0561 |
Loa Loa (eye worm) | hypothetical protein | 0.018 | 0.0334 | 0.2237 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0025 | 0.0022 | 0.0144 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0023 | 0.0017 | 0.09 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.011 | 0.0192 | 0.1738 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0029 | 0.0029 | 0.0159 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0034 | 0.0039 | 0.0258 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.04 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0034 | 0.0039 | 0.0258 |
Echinococcus multilocularis | musashi | 0.0058 | 0.0089 | 0.0088 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0016 | 0.0003 | 0.0018 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0034 | 0.0039 | 0.0038 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0017 | 0.0006 | 0.0006 |
Echinococcus multilocularis | lamin | 0.0058 | 0.0089 | 0.0088 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0018 | 0.0007 | 0.0042 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0192 | 0.1738 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.002 | 0.0013 | 0.0012 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0093 | 0.0121 |
Loa Loa (eye worm) | glutathione reductase | 0.0099 | 0.017 | 0.1137 |
Trypanosoma brucei | unspecified product | 0.002 | 0.0013 | 0.0666 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0023 | 0.0018 | 0.0115 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0023 | 0.0017 | 0.0725 |
Brugia malayi | nuclear receptor NHR-67 | 0.0016 | 0.0003 | 0.0019 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0029 | 0.0029 | 0.0159 |
Schistosoma mansoni | thyroid hormone receptor | 0.0159 | 0.029 | 0.1848 |
Loa Loa (eye worm) | beta-lactamase | 0.011 | 0.0192 | 0.1282 |
Echinococcus granulosus | geminin | 0.054 | 0.1055 | 0.6738 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0034 | 0.0039 | 0.0246 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0016 | 0.0003 | 0.0019 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0241 | 0.0454 | 0.0454 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0034 | 0.0039 | 0.0258 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0028 | 0.0028 | 0.0027 |
Echinococcus multilocularis | G protein coupled receptor 139 | 0.0487 | 0.0948 | 0.0948 |
Echinococcus multilocularis | ubiquitin carboxyl terminal hydrolase 8 | 0.004 | 0.0051 | 0.005 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0034 | 0.004 | 0.0268 |
Plasmodium vivax | glutathione reductase, putative | 0.0099 | 0.017 | 0.8837 |
Echinococcus multilocularis | mothers against decapentaplegic 6 | 0.0023 | 0.0018 | 0.0017 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0034 | 0.0039 | 0.0258 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0029 | 0.0191 |
Brugia malayi | AMP-binding enzyme family protein | 0.0029 | 0.0029 | 0.0191 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0029 | 0.0029 | 0.1278 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0099 | 0.017 | 0.8837 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0016 | 0.0003 | 0.0018 |
Loa Loa (eye worm) | intermediate filament protein | 0.0058 | 0.0089 | 0.059 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0028 | 0.0184 |
Schistosoma mansoni | hypothetical protein | 0.015 | 0.0273 | 0.1743 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.011 | 0.0192 | 0.1282 |
Schistosoma mansoni | smad1 5 8 and | 0.0052 | 0.0075 | 0.0475 |
Schistosoma mansoni | hypothetical protein | 0.054 | 0.1055 | 0.6738 |
Echinococcus granulosus | neuropeptide receptor | 0.0487 | 0.0948 | 0.6054 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0023 | 0.0017 | 0.0641 |
Schistosoma mansoni | intermediate filament proteins | 0.0058 | 0.0089 | 0.0561 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0034 | 0.0039 | 0.0038 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0756 | 0.1489 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0016 | 0.0003 | 0.0018 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.011 | 0.0192 | 1 |
Trypanosoma brucei | ubiquitin carboxyl-terminal hydrolase, putative | 0.004 | 0.0051 | 0.2669 |
Toxoplasma gondii | exonuclease III APE | 0.0023 | 0.0017 | 0.0017 |
Mycobacterium ulcerans | glutaminase | 0.0533 | 0.1041 | 1 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0021 | 0.0015 | 0.0018 |
Plasmodium falciparum | thioredoxin reductase | 0.0034 | 0.004 | 0.2129 |
Schistosoma mansoni | tar DNA-binding protein | 0.0397 | 0.0769 | 0.4906 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0093 | 0.4687 |
Trichomonas vaginalis | esterase, putative | 0.011 | 0.0192 | 0.1738 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0012 | 0.0051 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0225 | 0.0424 | 0.3052 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0093 | 0.0776 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0034 | 0.0039 | 0.0038 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.002 | 0.0013 | 0.0081 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.0273 | 1 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0023 | 0.0017 | 0.0111 |
Schistosoma mansoni | ubiquitin-specific peptidase 2 (C19 family) | 0.004 | 0.0051 | 0.0322 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.0273 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Echinococcus granulosus | tar DNA binding protein | 0.0397 | 0.0769 | 0.4906 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0034 | 0.004 | 0.7193 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0034 | 0.0039 | 0.0038 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0099 | 0.017 | 0.0169 |
Schistosoma mansoni | ap endonuclease | 0.0023 | 0.0017 | 0.0106 |
Plasmodium falciparum | thioredoxin reductase | 0.0099 | 0.017 | 1 |
Echinococcus multilocularis | isocitrate dehydrogenase 2 (NADP+) | 0.0017 | 0.0005 | 0.0005 |
Mycobacterium tuberculosis | Probable lipase LipE | 0.011 | 0.0192 | 0.1358 |
Brugia malayi | RNA binding protein | 0.0397 | 0.0769 | 0.516 |
Onchocerca volvulus | 0.0058 | 0.0089 | 0.3001 | |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Brugia malayi | MH1 domain containing protein | 0.0028 | 0.0029 | 0.0189 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0052 | 0.0075 | 0.0475 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0397 | 0.0769 | 0.516 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0029 | 0.0029 | 0.0159 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.017 | 0.1082 |
Echinococcus granulosus | intermediate filament protein | 0.0058 | 0.0089 | 0.0561 |
Trypanosoma brucei | hypothetical protein, conserved | 0.011 | 0.0192 | 1 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0029 | 0.0029 | 0.0627 |
Schistosoma mansoni | smad | 0.0052 | 0.0075 | 0.0475 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0192 | 0.1282 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0241 | 0.0454 | 0.3049 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.0089 | 0.059 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0034 | 0.0039 | 0.0258 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.04 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0034 | 0.0039 | 0.0258 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Trypanosoma cruzi | ubiquitin carboxyl-terminal hydrolase, putative | 0.004 | 0.0051 | 0.246 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0018 | 0.0007 | 0.0044 |
Brugia malayi | TAR-binding protein | 0.0397 | 0.0769 | 0.516 |
Echinococcus multilocularis | muscleblind protein | 0.018 | 0.0334 | 0.0333 |
Entamoeba histolytica | hypothetical protein | 0.015 | 0.0273 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0023 | 0.0017 | 0.0641 |
Loa Loa (eye worm) | nuclear factor I | 0.0028 | 0.0029 | 0.0189 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0093 |
Brugia malayi | steroid hormone receptor | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0241 | 0.0454 | 0.3049 |
Echinococcus multilocularis | Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 | 0.004 | 0.0051 | 0.005 |
Schistosoma mansoni | neuropeptide receptor | 0.0487 | 0.0948 | 0.6054 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0005 |
Brugia malayi | MH1 domain containing protein | 0.0052 | 0.0075 | 0.0499 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0099 | 0.017 | 0.1137 |
Schistosoma mansoni | NADP-specific isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0029 |
Echinococcus multilocularis | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0005 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0241 | 0.0454 | 0.2899 |
Schistosoma mansoni | hypothetical protein | 0.0099 | 0.017 | 0.1082 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0258 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0118 | 0.0209 | 0.1331 |
Onchocerca volvulus | 0.011 | 0.0192 | 0.6518 | |
Echinococcus granulosus | dna polymerase kappa | 0.002 | 0.0013 | 0.0077 |
Onchocerca volvulus | 0.0016 | 0.0003 | 0.0095 | |
Echinococcus granulosus | microtubule associated protein 2 | 0.0668 | 0.1313 | 0.8385 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0041 | 0.0055 | 0.0345 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0034 | 0.004 | 0.1882 |
Schistosoma mansoni | zinc finger protein | 0.0016 | 0.0003 | 0.0018 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0016 | 0.0003 | 0.0003 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.0454 | 0.2899 |
Onchocerca volvulus | 0.0058 | 0.0089 | 0.3001 | |
Brugia malayi | glutaminase DH11.1 | 0.0533 | 0.1041 | 0.6992 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0023 | 0.0017 | 0.0106 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0093 | 0.0587 |
Echinococcus multilocularis | smad | 0.0052 | 0.0075 | 0.0074 |
Mycobacterium tuberculosis | Probable esterase/lipase LipP | 0.011 | 0.0192 | 0.1358 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0258 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0016 | 0.0003 | 0.0003 |
Schistosoma mansoni | nuclear receptor | 0.0016 | 0.0003 | 0.0018 |
Leishmania major | trypanothione reductase | 0.0099 | 0.017 | 0.8837 |
Schistosoma mansoni | thyroid hormone receptor | 0.0159 | 0.029 | 0.1848 |
Echinococcus multilocularis | muscleblind protein 1 | 0.018 | 0.0334 | 0.0333 |
Loa Loa (eye worm) | Smad1 | 0.0052 | 0.0075 | 0.0499 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0016 | 0.0003 | 0.0019 |
Brugia malayi | nuclear receptor NHR-88 | 0.0016 | 0.0003 | 0.0019 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0125 | 0.0222 | 0.0222 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0013 | 0.0666 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0093 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0023 | 0.0017 | 0.1167 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.011 | 0.0192 | 0.1738 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.0454 | 0.2899 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0016 | 0.0003 | 0.0003 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0034 | 0.0039 | 0.0258 |
Trypanosoma brucei | isocitrate dehydrogenase [NADP], mitochondrial precursor, putative | 0.0017 | 0.0005 | 0.0277 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.025 | 0.0474 | 1 |
Onchocerca volvulus | 0.0056 | 0.0084 | 0.2831 | |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.015 | 0.0273 | 0.0273 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.015 | 0.0273 | 0.1743 |
Schistosoma mansoni | hypothetical protein | 0.054 | 0.1055 | 0.6738 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0034 | 0.004 | 0.1882 |
Schistosoma mansoni | survival motor neuron protein | 0.0052 | 0.0075 | 0.0477 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0052 | 0.0075 | 0.0499 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0214 | 0.04 | 0.2685 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0034 | 0.0039 | 0.0038 |
Brugia malayi | Muscleblind-like protein | 0.018 | 0.0334 | 0.2237 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0029 | 0.0029 | 0.0174 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0021 | 0.0015 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0007 | 0.0044 |
Mycobacterium ulcerans | fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE | 0.011 | 0.0192 | 0.1738 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0007 | 0.0044 |
Plasmodium falciparum | glutathione reductase | 0.0099 | 0.017 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0056 | 0.0084 | 0.0557 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0007 | 0.0044 |
Trichomonas vaginalis | glutaminase, putative | 0.0533 | 0.1041 | 1 |
Mycobacterium tuberculosis | Probable reductase | 0.0225 | 0.0424 | 0.3052 |
Mycobacterium tuberculosis | Probable esterase LipL | 0.011 | 0.0192 | 0.1358 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0031 | 0.0034 | 0.0226 |
Echinococcus granulosus | NADP dependent isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0029 |
Schistosoma mansoni | Smad4 | 0.0023 | 0.0018 | 0.011 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0668 | 0.1313 | 0.8385 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0028 | 0.0028 | 0.0175 |
Loa Loa (eye worm) | RNA binding protein | 0.0397 | 0.0769 | 0.516 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0034 | 0.0039 | 0.0246 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.002 | 0.0013 | 0.0081 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0086 | 0.0576 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.011 | 0.0192 | 0.1219 |
Brugia malayi | hypothetical protein | 0.015 | 0.0273 | 0.1833 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0023 | 0.0017 | 0.0087 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.025 | 0.0474 | 0.342 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0099 | 0.017 | 0.1138 |
Entamoeba histolytica | ubiquitin carboxyl-terminal hydrolase domain containing protein | 0.004 | 0.0051 | 0.1471 |
Loa Loa (eye worm) | acetyltransferase | 0.0141 | 0.0254 | 0.1703 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0225 | 0.0424 | 0.3052 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0093 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0029 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.016 | 0.0293 | 0.1967 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.015 | 0.0273 | 0.1743 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0015 | 0.0093 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0018 | 0.0007 | 0.0007 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0034 | 0.0039 | 0.0258 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0099 | 0.017 | 0.1082 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0012 | 0.0051 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0029 | 0.0029 | 0.0159 |
Brugia malayi | beta-lactamase family protein | 0.011 | 0.0192 | 0.1282 |
Mycobacterium ulcerans | esterase/lipase LipP | 0.011 | 0.0192 | 0.1738 |
Onchocerca volvulus | Mothers against decapentaplegic homolog | 0.0023 | 0.0018 | 0.0586 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0016 | 0.0003 | 0.0003 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0034 | 0.0039 | 0.0038 |
Echinococcus multilocularis | dna polymerase kappa | 0.002 | 0.0013 | 0.0012 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0023 | 0.0017 | 0.0111 |
Mycobacterium ulcerans | beta-lactamase | 0.011 | 0.0192 | 0.1738 |
Echinococcus granulosus | lamin dm0 | 0.0058 | 0.0089 | 0.0561 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0029 | 0.0029 | 0.0159 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0159 | 0.029 | 0.0289 |
Echinococcus multilocularis | isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0005 |
Schistosoma mansoni | nuclear hormone receptor | 0.0016 | 0.0003 | 0.0018 |
Brugia malayi | mothers against decapentaplegic homolog 3 | 0.0023 | 0.0018 | 0.0115 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0241 | 0.0454 | 0.0454 |
Echinococcus granulosus | lamin | 0.0058 | 0.0089 | 0.0561 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | histone methyltransferase | 0.0017 | 0.0006 | 0.0038 |
Trichomonas vaginalis | Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase | 0.004 | 0.0051 | 0.0373 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0034 | 0.0039 | 0.0258 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0093 | 0.0092 |
Schistosoma mansoni | tar DNA-binding protein | 0.0397 | 0.0769 | 0.4906 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0034 | 0.0039 | 0.0038 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Mycobacterium tuberculosis | Probable lipase LipD | 0.011 | 0.0192 | 0.1358 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0023 | 0.0017 | 0.0641 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0034 | 0.004 | 0.1882 |
Brugia malayi | Smad1 | 0.0052 | 0.0075 | 0.0499 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.0192 | 0.1282 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0041 | 0.0055 | 0.0408 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0034 | 0.004 | 0.1882 |
Brugia malayi | hypothetical protein | 0.016 | 0.0293 | 0.1967 |
Echinococcus granulosus | smad | 0.0052 | 0.0075 | 0.0475 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0034 | 0.0039 | 0.0258 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0056 | 0.0084 | 0.0557 |
Echinococcus granulosus | muscleblind protein | 0.018 | 0.0334 | 0.2127 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0141 | 0.0254 | 0.1703 |
Echinococcus multilocularis | lamin dm0 | 0.0058 | 0.0089 | 0.0088 |
Onchocerca volvulus | 0.0016 | 0.0003 | 0.0095 | |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0312 | 0.0599 | 0.4018 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0241 | 0.0454 | 0.2899 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.002 | 0.0013 | 0.0666 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.002 | 0.0013 | 0.0666 |
Onchocerca volvulus | 0.0034 | 0.0039 | 0.1313 | |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0099 | 0.0171 | 0.1088 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0034 | 0.004 | 0.1882 |
Loa Loa (eye worm) | hypothetical protein | 0.0214 | 0.04 | 0.2685 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.002 | 0.0012 | 0.0051 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.0454 | 0.2899 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0003 | 0.0019 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0007 | 0.0044 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0007 | 0.0044 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0093 | 0.0587 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0034 | 0.004 | 0.2106 |
Loa Loa (eye worm) | isocitrate dehydrogenase | 0.0017 | 0.0005 | 0.0031 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0029 | 0.0029 | 0.0627 |
Schistosoma mansoni | lamin | 0.0058 | 0.0089 | 0.0561 |
Mycobacterium leprae | conserved hypothetical protein | 0.011 | 0.0192 | 0.3649 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0312 | 0.0599 | 0.4018 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Potency (functional) | 89.1251 uM | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] | ChEMBL. | No reference |
Potency (functional) | 100 uM | PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.