Detailed information for compound 1169163

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 305.599 | Formula: C11H14BrClN2O
  • H donors: 0 H acceptors: 1 LogP: 2.89 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN(C1(CC1)COc1cnc(c(c1)Br)Cl)C
  • InChi: 1S/C11H14BrClN2O/c1-15(2)11(3-4-11)7-16-8-5-9(12)10(13)14-6-8/h5-6H,3-4,7H2,1-2H3
  • InChiKey: UGWDIIDORRQTIW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni hypothetical protein 0.0053 0.0132 0.0562
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0195 0.0584 0.2833
Loa Loa (eye worm) TYRA-2 protein 0.021 0.0631 0.3602
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.021 0.0631 0.3602
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.021 0.0631 0.0631
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0043 0.0099 1
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0085 0.0234 0.0234
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.021 0.0631 0.0631
Echinococcus granulosus orexin receptor type 2 0.021 0.0631 0.0631
Echinococcus multilocularis neuropeptide receptor A26 0.1666 0.5275 0.5275
Echinococcus granulosus 7tm_1 domain containing protein 0.021 0.0631 0.0631
Plasmodium vivax SET domain protein, putative 0.0029 0.0056 0.3873
Echinococcus granulosus importin subunit beta 1 0.0029 0.0055 0.0055
Brugia malayi larval opioid receptor 0.021 0.0631 0.3062
Loa Loa (eye worm) G-protein coupled receptor 0.021 0.0631 0.3602
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.021 0.0631 0.3062
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0195 0.0584 0.0584
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0029 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.007 0.0186 0.1062
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0076 0.1078
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.0631 0.0631
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Schistosoma mansoni neuropeptide f receptor 76f 0.021 0.0631 0.2686
Mycobacterium ulcerans cytochrome P450 142A3 Cyp142A3 0.0015 0.0009 0.0023
Brugia malayi G-protein coupled receptor 0.021 0.0631 0.3062
Brugia malayi Dopamine receptor protein 2 0.021 0.0631 0.3062
Onchocerca volvulus 0.028 0.0856 1
Echinococcus multilocularis conserved hypothetical protein 0.0672 0.2106 0.2106
Onchocerca volvulus 0.0233 0.0704 0.8226
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.021 0.0631 0.2686
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0014 0.0007 0.0007
Leishmania major cytochrome p450-like protein 0.0024 0.0038 1
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0195 0.0584 0.3332
Brugia malayi Serotonin receptor 0.021 0.0631 0.3062
Schistosoma mansoni biogenic amine (dopamine) receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus granulosus lamin dm0 0.0029 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0292 0.1242
Onchocerca volvulus 0.021 0.0631 0.7367
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.021 0.0631 0.3062
Mycobacterium tuberculosis Possible cytochrome P450 126 Cyp126 0.0015 0.0009 0.0023
Mycobacterium ulcerans cytochrome P450 124A1, Cyp124A1 0.0015 0.0009 0.0023
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0031 0.7478
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.0631 0.0631
Mycobacterium tuberculosis Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) 0.0015 0.0009 0.0023
Mycobacterium ulcerans cytochrome P450 140A5 Cyp140A5 0.0015 0.0009 0.0023
Onchocerca volvulus Putative nachr subunit 0.0195 0.0584 0.6817
Brugia malayi Cation transporter family protein 0.0195 0.0584 0.2833
Onchocerca volvulus 0.021 0.0631 0.7367
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0292 0.1242
Brugia malayi Carboxylesterase family protein 0.007 0.0186 0.0903
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.021 0.0631 0.3602
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Echinococcus multilocularis neuropeptide Y receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.021 0.0631 0.3602
Brugia malayi Cation transporter family protein 0.028 0.0856 0.4156
Loa Loa (eye worm) melatonin receptor type 1A 0.021 0.0631 0.3602
Schistosoma mansoni acetylcholine receptor-related 0.0085 0.0234 0.0998
Onchocerca volvulus 0.021 0.0631 0.7367
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0021 0.0028 0.0028
Echinococcus granulosus tm gpcr rhodopsin 0.021 0.0631 0.0631
Brugia malayi Intermediate filament tail domain containing protein 0.0029 0.0055 0.0269
Schistosoma mansoni cytochrome P450 0.0015 0.0009 0.0038
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0043 0.0099 0.1412
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.021 0.0631 0.0631
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.011 0.0312 0.1512
Mycobacterium ulcerans cytochrome P450 189A7 Cyp189A7 0.0015 0.0009 0.0023
Echinococcus granulosus neuropeptide receptor 0.021 0.0631 0.0631
Echinococcus granulosus carboxylesterase 5A 0.007 0.0186 0.0186
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0195 0.0584 0.2833
Brugia malayi Serotonin/octopamine receptor family protein 7 0.021 0.0631 0.3062
Echinococcus granulosus neuropeptides capa receptor 0.021 0.0631 0.0631
Brugia malayi Dopamine receptor 0.021 0.0631 0.3062
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus granulosus histone lysine methyltransferase setb 0.0029 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.011 0.0312 0.1779
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0028 0.0398
Schistosoma mansoni nAChR subunit 0.0195 0.0584 0.2485
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.021 0.0631 0.0631
Mycobacterium ulcerans cytochrome P450 187A5 Cyp187A5 0.0015 0.0009 0.0023
Schistosoma mansoni apoptosis regulator bax 0.0561 0.1752 0.7457
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Schistosoma mansoni neuropeptide F-like receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Echinococcus granulosus tm gpcr rhodopsin 0.021 0.0631 0.0631
Brugia malayi ORL1-like opioid receptor 0.021 0.0631 0.3062
Onchocerca volvulus 0.021 0.0631 0.7367
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.021 0.0631 0.3602
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0195 0.0584 0.2833
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Loa Loa (eye worm) hypothetical protein 0.028 0.0856 0.4889
Loa Loa (eye worm) hypothetical protein 0.011 0.0312 0.1779
Brugia malayi Pre-SET motif family protein 0.0204 0.0614 0.2982
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Schistosoma mansoni hypothetical protein 0.0561 0.1752 0.7457
Mycobacterium ulcerans cytochrome P450 126A3 Cyp126A3 0.0015 0.0009 0.0023
Onchocerca volvulus Neuropeptide F receptor homolog 0.021 0.0631 0.7367
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0056 0.0237
Schistosoma mansoni nAChR subunit 0.0195 0.0584 0.2485
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0014 0.0007 0.0007
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0021 0.0028 0.0072
Echinococcus granulosus glycine receptor subunit alpha 1 0.0195 0.0584 0.0584
Echinococcus granulosus tm gpcr rhodopsin 0.021 0.0631 0.0631
Echinococcus multilocularis sex peptide receptor 0.021 0.0631 0.0631
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.0794 0.0794
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Onchocerca volvulus 0.021 0.0631 0.7367
Echinococcus multilocularis g protein coupled receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Trichomonas vaginalis bromodomain-containing protein, putative 0.0043 0.0099 0.1412
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0195 0.0584 0.0584
Schistosoma mansoni lamin 0.0029 0.0055 0.0236
Echinococcus multilocularis neuropeptide Y receptor 0.021 0.0631 0.0631
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0561 0.1752 0.7457
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Brugia malayi putative neuropeptide receptor NPR1 0.021 0.0631 0.3062
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0195 0.0584 0.2833
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0095 0.0405
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0038 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0195 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.011 0.0312 0.1779
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0031 0.7478
Mycobacterium ulcerans naphthoate synthase 0.124 0.3916 1
Onchocerca volvulus 0.0195 0.0584 0.6817
Onchocerca volvulus 0.021 0.0631 0.7367
Mycobacterium ulcerans cytochrome P450 144A4 Cyp144A4 0.0015 0.0009 0.0023
Echinococcus multilocularis g protein coupled receptor 0.021 0.0631 0.0631
Brugia malayi exodeoxyribonuclease III family protein 0.0021 0.0028 0.0136
Loa Loa (eye worm) neuropeptide F receptor 0.021 0.0631 0.3602
Echinococcus multilocularis acetylcholinesterase 0.007 0.0186 0.0186
Echinococcus granulosus g protein coupled receptor 0.021 0.0631 0.0631
Mycobacterium tuberculosis Probable cytochrome P450 125 Cyp125 0.0015 0.0009 0.0023
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0195 0.0584 0.0584
Onchocerca volvulus 0.021 0.0631 0.7367
Entamoeba histolytica acetyltransferase, GNAT family 0.0039 0.0088 0.2116
Brugia malayi sulfakinin receptor protein 0.021 0.0631 0.3062
Mycobacterium tuberculosis Probable cytochrome P450 136 Cyp136 0.0015 0.0009 0.0023
Onchocerca volvulus 0.0195 0.0584 0.6817
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0146 0.0429 0.0429
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0561 0.1752 0.1752
Brugia malayi Cytochrome P450 family protein 0.0034 0.0072 0.0349
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus multilocularis alpha 1A adrenergic receptor 0.021 0.0631 0.0631
Echinococcus granulosus G protein coupled receptor 139 0.021 0.0631 0.0631
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0195 0.0584 0.2833
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0031 0.0414
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.021 0.0631 0.0631
Mycobacterium ulcerans cytochrome P450 150A6 Cyp150A6 0.0015 0.0009 0.0023
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0195 0.0584 0.0584
Loa Loa (eye worm) GABA receptor subunit 0.011 0.0312 0.1779
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0031 0.0414
Echinococcus granulosus neuropeptide Y receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Trypanosoma brucei cytochrome P450, putative 0.0024 0.0038 0.6267
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0038 0.0532
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0195 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Schistosoma mansoni voltage-gated potassium channel 0.0042 0.0095 0.0405
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0195 0.0584 0.0584
Schistosoma mansoni amine GPCR 0.021 0.0631 0.2686
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.021 0.0631 0.2686
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.011 0.0312 0.1512
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0043 0.0099 1
Schistosoma mansoni hypothetical protein 0.021 0.0631 0.2686
Schistosoma mansoni neurotransmitter gated ion channel 0.0085 0.0234 0.0998
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Brugia malayi hypothetical protein 0.0261 0.0794 0.3856
Schistosoma mansoni opsin-like receptor 0.021 0.0631 0.2686
Onchocerca volvulus 0.021 0.0631 0.7367
Brugia malayi hypothetical protein 0.0085 0.0234 0.1137
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0195 0.0584 0.3332
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0195 0.0584 0.2485
Schistosoma mansoni amine GPCR 0.021 0.0631 0.2686
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.011 0.0312 0.1779
Loa Loa (eye worm) hypothetical protein 0.0029 0.0056 0.0318
Schistosoma mansoni neuropeptide receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) LGC-31 protein 0.0195 0.0584 0.3332
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0311 0.0954 0.5445
Onchocerca volvulus 0.021 0.0631 0.7367
Echinococcus multilocularis glycine receptor subunit beta 0.0195 0.0584 0.0584
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.011 0.0312 0.1512
Brugia malayi acetyltransferase, GNAT family protein 0.0146 0.0429 0.2083
Onchocerca volvulus 0.028 0.0856 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.0631 0.0631
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.0631 0.0631
Mycobacterium ulcerans cytochrome P450 136A2 Cyp136A2 0.0015 0.0009 0.0023
Schistosoma mansoni opsin-like receptor 0.021 0.0631 0.2686
Mycobacterium ulcerans cytochrome P450 143A3 Cyp143A3 0.0015 0.0009 0.0023
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0085 0.0234 0.1137
Schistosoma mansoni growth hormone secretagogue receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0038 0.0084 0.0479
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0195 0.0584 0.2833
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Loa Loa (eye worm) follicle stimulating hormone receptor 0.021 0.0631 0.3602
Onchocerca volvulus 0.021 0.0631 0.7367
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0561 0.1752 0.8502
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0292 0.1242
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Mycobacterium ulcerans cytochrome P450 188A3 Cyp188A3 0.0015 0.0009 0.0023
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0195 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.011 0.0312 0.1779
Schistosoma mansoni hypothetical protein 0.0561 0.1752 0.7457
Loa Loa (eye worm) hypothetical protein 0.0029 0.0055 0.0314
Brugia malayi G-protein coupled receptor 0.021 0.0631 0.3062
Brugia malayi follicle stimulating hormone receptor 0.021 0.0631 0.3062
Echinococcus multilocularis biogenic amine (5HT) receptor 0.021 0.0631 0.0631
Mycobacterium tuberculosis Probable cytochrome P450 monooxygenase 142 Cyp142 0.0015 0.0009 0.0023
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0055 1
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0085 0.0234 0.0234
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0103 0.0292 0.1665
Echinococcus granulosus neuropeptide receptor 0.021 0.0631 0.0631
Onchocerca volvulus 0.0029 0.0056 0.0651
Mycobacterium tuberculosis Probable cytochrome P450 128 Cyp128 0.0015 0.0009 0.0023
Onchocerca volvulus 0.0085 0.0234 0.2736
Echinococcus granulosus neuropeptide receptor A26 0.1666 0.5275 0.5275
Echinococcus multilocularis 0.0015 0.0009 0.0009
Echinococcus multilocularis neuropeptide receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0014 0.0005 0.0031
Schistosoma mansoni ap endonuclease 0.0021 0.0028 0.0119
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.0631 0.0631
Giardia lamblia Histone acetyltransferase GCN5 0.0039 0.0088 1
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Schistosoma mansoni biogenic amine receptor 0.021 0.0631 0.2686
Echinococcus granulosus histone acetyltransferase KAT2B 0.0043 0.0099 0.0099
Schistosoma mansoni microtubule-associated protein tau 0.0748 0.2349 1
Schistosoma mansoni hypothetical protein 0.0311 0.0954 0.4061
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0029 0.0056 0.0056
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0031 0.0031
Entamoeba histolytica hypothetical protein 0.011 0.0312 1
Mycobacterium tuberculosis Probable cytochrome P450 144 Cyp144 0.0015 0.0009 0.0023
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.021 0.0631 0.0631
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0146 0.0429 0.1827
Loa Loa (eye worm) acetylcholinesterase 1 0.007 0.0186 0.1062
Echinococcus granulosus serotonin receptor 0.021 0.0631 0.0631
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0195 0.0584 0.0584
Echinococcus multilocularis neuropeptides capa receptor 0.021 0.0631 0.0631
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0195 0.0584 0.0584
Schistosoma mansoni biogenic amine (dopamine) receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0021 0.0028 0.016
Mycobacterium ulcerans cytochrome P450 143A4 Cyp143A4 0.0015 0.0009 0.0023
Plasmodium vivax importin-beta 2, putative 0.0029 0.0055 0.3781
Echinococcus granulosus g protein coupled receptor 0.021 0.0631 0.0631
Mycobacterium ulcerans cytochrome P450 125A7 Cyp125A7 0.0015 0.0009 0.0023
Schistosoma mansoni ran 0.0021 0.0031 0.013
Loa Loa (eye worm) apoptosis regulator protein 0.0561 0.1752 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0195 0.0584 0.2833
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0021 0.0028 0.0028
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0031 0.2388
Schistosoma mansoni amine GPCR 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) hypothetical protein 0.0561 0.1752 1
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0021 0.0028 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.0631 0.0631
Echinococcus granulosus snurportin 1 0.0311 0.0954 0.0954
Mycobacterium tuberculosis Possible cytochrome P450 135B1 Cyp135B1 0.0015 0.0009 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0085 0.0234 0.1338
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0038 0.0532
Echinococcus granulosus fmrfamide receptor 0.021 0.0631 0.0631
Schistosoma mansoni neuropeptide receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0031 0.0174
Mycobacterium tuberculosis Probable cytochrome P450 130 Cyp130 0.0015 0.0009 0.0023
Leishmania major GTP-binding protein, putative 0.0021 0.0031 0.7478
Loa Loa (eye worm) hypothetical protein 0.0014 0.0007 0.0041
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.021 0.0631 0.2686
Trichomonas vaginalis ap endonuclease, putative 0.0021 0.0028 0.0398
Echinococcus multilocularis allatostatin A receptor 0.021 0.0631 0.0631
Mycobacterium tuberculosis Probable cytochrome P450 137 Cyp137 0.0015 0.0009 0.0023
Mycobacterium tuberculosis Probable cytochrome P450 139 Cyp139 0.0015 0.0009 0.0023
Onchocerca volvulus 0.021 0.0631 0.7367
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0195 0.0584 0.0584
Brugia malayi intermediate filament protein 0.0029 0.0055 0.0269
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3335
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0029 0.0056 0.0237
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0021 0.0028 0.6619
Echinococcus multilocularis neuropeptide receptor 0.021 0.0631 0.0631
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0031 0.0148
Echinococcus granulosus acetylcholinesterase 0.007 0.0186 0.0186
Loa Loa (eye worm) hypothetical protein 0.007 0.0186 0.1062
Echinococcus granulosus 7TM GPCR rhodopsin 0.021 0.0631 0.0631
Schistosoma mansoni hypothetical protein 0.0561 0.1752 0.7457
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Schistosoma mansoni histamine h1 receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) ACC-1 protein 0.0195 0.0584 0.3332
Loa Loa (eye worm) neuropeptide F receptor 0.021 0.0631 0.3602
Onchocerca volvulus 0.0053 0.0132 0.1541
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0021 0.0028 0.6619
Echinococcus granulosus alpha 1A adrenergic receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Onchocerca volvulus 0.021 0.0631 0.7367
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) ACC-1 protein 0.0195 0.0584 0.3332
Schistosoma mansoni neurotransmitter gated ion channel 0.011 0.0312 0.1326
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0038 0.0084 0.0084
Brugia malayi Tachykinin-like peptides receptor 99D 0.021 0.0631 0.3062
Schistosoma mansoni ap endonuclease 0.0021 0.0028 0.0119
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0195 0.0584 0.2833
Loa Loa (eye worm) hypothetical protein 0.0261 0.0794 0.4536
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.021 0.0631 0.0631
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0085 0.0234 0.1137
Brugia malayi neuropeptide F receptor 0.021 0.0631 0.3062
Trichomonas vaginalis ran, putative 0.0021 0.0031 0.0434
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Schistosoma mansoni nAChR subunit 0.0195 0.0584 0.2485
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0085 0.0234 0.1338
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0029 0.0054 0.0307
Loa Loa (eye worm) intermediate filament protein 0.0029 0.0055 0.0317
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.007 0.0186 0.0792
Echinococcus multilocularis lamin 0.0029 0.0055 0.0055
Onchocerca volvulus 0.0085 0.0234 0.2736
Brugia malayi GnHR receptor homolog 0.021 0.0631 0.3062
Schistosoma mansoni opsin-like receptor 0.021 0.0631 0.2686
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0021 0.0028 0.6619
Brugia malayi Pre-SET motif family protein 0.0029 0.0056 0.027
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) hypothetical protein 0.011 0.0312 0.1779
Schistosoma mansoni acetylcholine receptor subunit beta 0.0085 0.0234 0.0998
Echinococcus multilocularis carboxylesterase 5A 0.007 0.0186 0.0186
Brugia malayi cytochrome P450 0.0015 0.0009 0.0043
Schistosoma mansoni myosin xvIII 0.021 0.0631 0.2686
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0052 0.0052
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0195 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0195 0.0584 0.2485
Echinococcus multilocularis dro:myosuppressin receptor 0.021 0.0631 0.0631
Echinococcus multilocularis fmrfamide receptor 0.021 0.0631 0.0631
Echinococcus granulosus allatostatin A receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Echinococcus granulosus neuropeptide Y receptor 0.021 0.0631 0.0631
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0024 0.0038 0.0097
Echinococcus granulosus biogenic amine 5HT receptor 0.021 0.0631 0.0631
Mycobacterium tuberculosis Probable cytochrome P450 123 Cyp123 0.0015 0.0009 0.0023
Echinococcus granulosus microtubule associated protein 2 0.0748 0.2349 0.2349
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0038 0.0216
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0055 0.0055
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Schistosoma mansoni neurotransmitter gated ion channel 0.0085 0.0234 0.0998
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.0631 0.0631
Brugia malayi Cation transporter family protein 0.0195 0.0584 0.2833
Brugia malayi hypothetical protein 0.0085 0.0234 0.1137
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0038 0.0216
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0195 0.0584 0.0584
Schistosoma mansoni nAChR subunit 0.0085 0.0234 0.0998
Schistosoma mansoni adenoreceptor 0.021 0.0631 0.2686
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Trypanosoma cruzi cytochrome P450, putative 0.0024 0.0038 1
Echinococcus multilocularis fmrfamide receptor 0.021 0.0631 0.0631
Mycobacterium ulcerans cytochrome P450 51B1 Cyp51B1 0.0015 0.0009 0.0023
Echinococcus multilocularis lamin dm0 0.0029 0.0055 0.0055
Brugia malayi RNA, U transporter 1 0.0083 0.0226 0.1098
Treponema pallidum exodeoxyribonuclease (exoA) 0.0021 0.0028 0.5
Schistosoma mansoni survival motor neuron protein 0.0053 0.0132 0.0562
Schistosoma mansoni biogenic amine (5HT) receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0029 0.0055 0.0317
Mycobacterium tuberculosis Probable cytochrome P450 124 Cyp124 0.0015 0.0009 0.0023
Brugia malayi AKH receptor 0.021 0.0631 0.3062
Loa Loa (eye worm) hypothetical protein 0.0033 0.0068 0.0388
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0195 0.0584 0.2833
Schistosoma mansoni hypothetical protein 0.0015 0.0009 0.0038
Brugia malayi Cytochrome P450 family protein 0.0024 0.0038 0.0184
Schistosoma mansoni nAChR subunit 0.0195 0.0584 0.2485
Mycobacterium ulcerans cytochrome P450 191A3 Cyp191A3 0.0015 0.0009 0.0023
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Onchocerca volvulus 0.0085 0.0234 0.2736
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0195 0.0584 0.2485
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.021 0.0631 0.2686
Echinococcus multilocularis acetylcholinesterase 0.007 0.0186 0.0186
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.011 0.0312 0.1512
Echinococcus multilocularis microtubule associated protein 2 0.0748 0.2349 0.2349
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.0631 0.0631
Schistosoma mansoni alpha-1 adrenergic receptor 0.021 0.0631 0.2686
Echinococcus granulosus neuropeptide FF receptor 2 0.021 0.0631 0.0631
Echinococcus granulosus lamin 0.0029 0.0055 0.0055
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Echinococcus granulosus neuropeptides capa receptor 0.021 0.0631 0.0631
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0195 0.0584 0.2833
Echinococcus multilocularis musashi 0.0029 0.0055 0.0055
Echinococcus multilocularis orexin receptor type 2 0.021 0.0631 0.0631
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Echinococcus multilocularis glycine receptor subunit beta 0.0195 0.0584 0.0584
Echinococcus granulosus somatostatin receptor 0.021 0.0631 0.0631
Echinococcus granulosus hypothetical protein 0.0882 0.2775 0.2775
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.028 0.0856 0.3646
Onchocerca volvulus 0.0029 0.0055 0.0648
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0021 0.0028 0.4149
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0195 0.0584 0.2833
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0195 0.0584 0.2833
Loa Loa (eye worm) hypothetical protein 0.028 0.0856 0.4889
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0103 0.0292 0.0292
Mycobacterium ulcerans cytochrome P450 105Q4 Cyp105Q4 0.0015 0.0009 0.0023
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0103 0.0292 0.1416
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0085 0.0234 0.1137
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0704 1
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Onchocerca volvulus 0.011 0.0312 0.3639
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0195 0.0584 0.2833
Echinococcus granulosus peptide allatostatin:somatostatin 0.021 0.0631 0.0631
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0038 0.0084 0.0084
Mycobacterium tuberculosis Naphthoate synthase MenB (dihydroxynaphthoic acid synthetase) (DHNA synthetase) 0.124 0.3916 1
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Mycobacterium leprae PROBABLE NAPHTHOATE SYNTHASE MENB (DIHYDROXYNAPHTHOIC ACID SYNTHETASE) (DHNA SYNTHETASE) 0.124 0.3916 1
Echinococcus granulosus intermediate filament protein 0.0029 0.0055 0.0055
Mycobacterium tuberculosis Probable cytochrome P450 143 Cyp143 0.0015 0.0009 0.0023
Echinococcus multilocularis nAChR subunit 0.011 0.0312 0.0312
Echinococcus multilocularis tachykinin peptides receptor 99D 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.011 0.0312 0.1779
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0204 0.0614 0.3507
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0103 0.0292 0.0292
Schistosoma mansoni amine GPCR 0.021 0.0631 0.2686
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0195 0.0584 0.3332
Echinococcus granulosus neuropeptide s receptor 0.1666 0.5275 0.5275
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Plasmodium falciparum histone acetyltransferase GCN5 0.0039 0.0088 1
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0085 0.0234 0.1137
Onchocerca volvulus 0.021 0.0631 0.7367
Schistosoma mansoni neuropeptide F-like receptor 0.021 0.0631 0.2686
Brugia malayi hypothetical protein 0.0085 0.0234 0.1137
Onchocerca volvulus 0.021 0.0631 0.7367
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.3147 1 1
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.011 0.0312 0.1326
Echinococcus granulosus sex peptide receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0195 0.0584 0.0584
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.0794 0.0794
Echinococcus multilocularis serotonin receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus multilocularis serotonin receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0029 0.0055 0.0317
Loa Loa (eye worm) cytochrome P450 family protein 0.0034 0.0072 0.0411
Schistosoma mansoni biogenic amine (5HT) receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0038 0.0532
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.021 0.0631 0.0631
Mycobacterium tuberculosis Probable cytochrome P450 138 Cyp138 0.0015 0.0009 0.0023
Mycobacterium ulcerans cytochrome P450 123A3 Cyp123A3 0.0015 0.0009 0.0023
Echinococcus granulosus biogenic amine 5HT receptor 0.021 0.0631 0.0631
Echinococcus granulosus g protein coupled receptor 0.021 0.0631 0.0631
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.021 0.0631 0.7367
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0195 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Onchocerca volvulus 0.028 0.0856 1
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus granulosus nAChR subunit 0.0195 0.0584 0.0584
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Echinococcus multilocularis snurportin 1 0.0311 0.0954 0.0954
Echinococcus granulosus dro:myosuppressin receptor 0.021 0.0631 0.0631
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0043 0.0099 1
Schistosoma mansoni nAChR subunit 0.0085 0.0234 0.0998
Mycobacterium ulcerans cytochrome p450 150 cyp150 0.0015 0.0009 0.0023
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0195 0.0584 0.2833
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0879 0.2767 0.2767
Schistosoma mansoni nAChR subunit 0.0195 0.0584 0.2485
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.021 0.0631 0.2686
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0012 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.0631 0.0631
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0085 0.0234 0.0234
Brugia malayi RE15519p 0.021 0.0631 0.3062
Loa Loa (eye worm) acetylcholine receptor protein 0.0085 0.0234 0.1338
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Echinococcus multilocularis neuropeptide s receptor 0.1666 0.5275 0.5275
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0085 0.0234 0.1137
Onchocerca volvulus 0.021 0.0631 0.7367
Mycobacterium ulcerans cytochrome P450 187A4 Cyp187A4 0.0015 0.0009 0.0023
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Mycobacterium tuberculosis Probable cytochrome P450 140 Cyp140 0.0015 0.0009 0.0023
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0085 0.0234 0.1137
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0012 0.0069
Brugia malayi Carboxylesterase family protein 0.007 0.0186 0.0903
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0195 0.0584 0.2833
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0021 0.0028 0.0072
Brugia malayi Melatonin receptor type 1A 0.021 0.0631 0.3062
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.0631 0.0631
Brugia malayi neuropeptide F receptor 0.021 0.0631 0.3062
Brugia malayi Cytochrome P450 family protein 0.0024 0.0038 0.0184
Echinococcus multilocularis neuropeptide FF receptor 2 0.021 0.0631 0.0631
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.021 0.0631 0.3062
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Brugia malayi Importin beta-1 subunit 0.0029 0.0055 0.0267
Echinococcus granulosus cytochrome P450 2K1 0.0015 0.0009 0.0009
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0561 0.1752 0.1752
Onchocerca volvulus 0.0029 0.0055 0.0648
Brugia malayi hypothetical protein 0.0085 0.0234 0.1137
Mycobacterium tuberculosis Possible cytochrome P450 135A1 Cyp135A1 0.0015 0.0009 0.0023
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0195 0.0584 0.0584
Echinococcus multilocularis rhodopsin orphan GPCR 0.021 0.0631 0.0631
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.021 0.0631 0.0631
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0103 0.0292 0.0292
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Loa Loa (eye worm) cytochrome P450 0.0015 0.0009 0.0051
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Echinococcus multilocularis neuropeptides capa receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Mycobacterium ulcerans cytochrome P450 108B4 Cyp108B4 0.0015 0.0009 0.0023
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Echinococcus multilocularis somatostatin receptor 0.021 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0195 0.0584 0.2485
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus granulosus nAChR subunit 0.011 0.0312 0.0312
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Schistosoma mansoni intermediate filament proteins 0.0029 0.0055 0.0236
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Entamoeba histolytica Ran family GTPase 0.0021 0.0031 0.0088
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0031 0.4686
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0132 0.0641
Brugia malayi Dopamine receptor protein 1 0.021 0.0631 0.3062
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.021 0.0631 0.0631
Brugia malayi G protein-coupled receptor 0.021 0.0631 0.3062
Leishmania major importin beta-1 subunit, putative 0.0024 0.0038 0.9883
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0031 0.0031
Echinococcus multilocularis g-protein coupled receptor 0.021 0.0631 0.0631
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Brugia malayi G protein-coupled receptor F59B2.13 0.021 0.0631 0.3062
Echinococcus multilocularis nAChR subunit 0.0195 0.0584 0.0584
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0055 0.5096
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0085 0.0234 0.0234
Schistosoma mansoni hypothetical protein 0.021 0.0631 0.2686
Schistosoma mansoni rhodopsin-like orphan GPCR 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Brugia malayi Serotonin receptor 0.0658 0.206 1
Schistosoma mansoni hypothetical protein 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Echinococcus granulosus glycine receptor subunit beta 0.0195 0.0584 0.0584
Schistosoma mansoni importin beta-1 0.0029 0.0055 0.0234
Echinococcus multilocularis G-protein coupled receptor, putative 0.021 0.0631 0.0631
Schistosoma mansoni ran 0.0021 0.0031 0.013
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Brugia malayi hypothetical protein 0.021 0.0631 0.3062
Entamoeba histolytica hypothetical protein 0.0024 0.0038 0.0333
Brugia malayi excitatory GABA receptor EXP-1A 0.0195 0.0584 0.2833
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Schistosoma mansoni biogenic amine receptor 0.021 0.0631 0.2686
Echinococcus granulosus acetylcholinesterase 0.007 0.0186 0.0186
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0038 0.0216
Loa Loa (eye worm) G-protein coupled receptor 0.021 0.0631 0.3602
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0195 0.0584 0.0584
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.028 0.0856 0.3646
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0038 0.0084 0.0408
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0195 0.0584 0.3332
Schistosoma mansoni amine GPCR 0.0532 0.166 0.7068
Echinococcus multilocularis g protein coupled receptor 0.021 0.0631 0.0631
Onchocerca volvulus 0.021 0.0631 0.7367
Onchocerca volvulus 0.011 0.0312 0.3639
Onchocerca volvulus 0.021 0.0631 0.7367
Schistosoma mansoni nAChR subunit 0.0195 0.0584 0.2485
Toxoplasma gondii exonuclease III APE 0.0021 0.0028 0.2114
Echinococcus granulosus g-protein coupled receptor 0.021 0.0631 0.0631
Mycobacterium tuberculosis Cytochrome P450 121 Cyp121 0.0015 0.0009 0.0023
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0036 0.0076 0.1078
Loa Loa (eye worm) acetyltransferase 0.0146 0.0429 0.245
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0056 0.0237
Loa Loa (eye worm) hypothetical protein 0.0195 0.0584 0.3332
Loa Loa (eye worm) carboxylesterase 0.007 0.0186 0.1062
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.0631 0.0631
Plasmodium falciparum importin beta, putative 0.0029 0.0055 0.4502
Echinococcus multilocularis G protein coupled receptor 139 0.021 0.0631 0.0631
Echinococcus granulosus glycine receptor subunit beta 0.0195 0.0584 0.0584
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0195 0.0584 0.0584
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0195 0.0584 0.2833
Mycobacterium tuberculosis Probable cytochrome P450 141 Cyp141 0.0015 0.0009 0.0023
Schistosoma mansoni lamin 0.0029 0.0055 0.0236
Mycobacterium tuberculosis Probable cytochrome P450 132 Cyp132 0.0015 0.0009 0.0023
Brugia malayi Cytochrome P450 family protein 0.0015 0.0009 0.0043
Schistosoma mansoni biogenic amine (dopamine) receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.011 0.0312 0.1326
Echinococcus granulosus histone acetyltransferase KAT2B 0.0142 0.0416 0.0416
Schistosoma mansoni nAChR subunit 0.0195 0.0584 0.2485
Loa Loa (eye worm) hypothetical protein 0.011 0.0312 0.1779
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0103 0.0292 0.0292
Brugia malayi putative neuropeptide receptor 0.021 0.0631 0.3062
Brugia malayi gonadotropin-releasing hormone receptor 2 0.021 0.0631 0.3062
Echinococcus granulosus glycine receptor subunit alpha 1 0.0195 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.021 0.0631 0.3602
Onchocerca volvulus 0.0195 0.0584 0.6817
Brugia malayi hypothetical protein 0.0085 0.0234 0.1137
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0195 0.0584 0.3332
Schistosoma mansoni hypothetical protein 0.021 0.0631 0.2686
Schistosoma mansoni biogenic amine receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) hypothetical protein 0.0085 0.0234 0.1338
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0055 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.021 0.0631 0.0631
Echinococcus granulosus rhodopsin orphan GPCR 0.021 0.0631 0.0631
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0029 0.0056 0.5168
Schistosoma mansoni neuropeptide receptor 0.021 0.0631 0.2686
Schistosoma mansoni neuropeptide receptor 0.021 0.0631 0.2686
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0195 0.0584 0.3332
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0038 0.9883
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0029 0.0056 0.0237
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0031 0.0348
Echinococcus granulosus glycine receptor subunit alpha 1 0.0195 0.0584 0.0584
Echinococcus granulosus thyrotropin releasing hormone receptor 0.021 0.0631 0.0631
Echinococcus granulosus tachykinin peptides receptor 99D 0.021 0.0631 0.0631
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0085 0.0234 0.0234
Schistosoma mansoni peptide (allatostatin)-like receptor 0.021 0.0631 0.2686

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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