Detailed information for compound 1256836

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 395.397 | Formula: C15H20F3N3O4S
  • H donors: 2 H acceptors: 3 LogP: 2.32 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCS(=O)(=O)N1CCC(CC1)NC(=O)Nc1ccc(cc1)OC(F)(F)F
  • InChi: 1S/C15H20F3N3O4S/c1-2-26(23,24)21-9-7-12(8-10-21)20-14(22)19-11-3-5-13(6-4-11)25-15(16,17)18/h3-6,12H,2,7-10H2,1H3,(H2,19,20,22)
  • InChiKey: VHDNEAFNRKTMDL-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens epoxide hydrolase 2, cytoplasmic Starlite/ChEMBL References
Mus musculus epoxide hydrolase 2, cytoplasmic Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) Get druggable targets OG5_129061 All targets in OG5_129061
Mycobacterium ulcerans epoxide hydrolase EphA Get druggable targets OG5_129061 All targets in OG5_129061
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0099 0.09
Echinococcus multilocularis G-protein coupled receptor, putative 0.005 0.0391 0.0485
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0099 0.0163
Schistosoma mansoni hypothetical protein 0.0419 0.464 0.5835
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni glucose transport protein 0.0208 0.2218 0.2789
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0166 0.037
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0391 0.0492
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.0391 0.0766
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Onchocerca volvulus Matrilysin homolog 0.0044 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.0062 0.0539 0.106
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Onchocerca volvulus 0.0453 0.504 1
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0334 0.3663 1
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Loa Loa (eye worm) hypothetical protein 0.0125 0.1264 0.2499
Loa Loa (eye worm) follicle stimulating hormone receptor 0.005 0.0391 0.0766
Brugia malayi Matrixin family protein 0.0048 0.0374 0.0732
Echinococcus multilocularis sex peptide receptor 0.005 0.0391 0.0485
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.005 0.0391 0.0485
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.0391 0.0492
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.0055 0.0451 0.0885
Loa Loa (eye worm) matrix metalloproteinase 0.002 0.0049 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0188 0.023
Echinococcus multilocularis g-protein coupled receptor 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.0125 0.1264 0.2499
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0395 0.4366 1
Echinococcus multilocularis fmrfamide receptor 0.005 0.0391 0.0485
Onchocerca volvulus 0.0029 0.0157 0.0216
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0157 0.0322
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus multilocularis g protein coupled receptor 0.005 0.0391 0.0485
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0064 0.0555 0.0706
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0007
Brugia malayi putative neuropeptide receptor 0.005 0.0391 0.0766
Mycobacterium ulcerans epoxide hydrolase EphA 0.0395 0.4366 1
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0564 0.1466
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Brugia malayi ORL1-like opioid receptor 0.005 0.0391 0.0766
Onchocerca volvulus 0.005 0.0391 0.0686
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0024 0.003
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0137 0.1399 0.1753
Echinococcus multilocularis cpg binding protein 0.0033 0.02 0.0245
Schistosoma mansoni hypothetical protein 0.0035 0.0221 0.0278
Onchocerca volvulus 0.0085 0.08 0.1504
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0157 0.0129
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0391 0.0485
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0334 0.3663 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.005 0.0391 0.0686
Brugia malayi G protein-coupled receptor F59B2.13 0.005 0.0391 0.0766
Onchocerca volvulus 0.005 0.0391 0.0686
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0188 0.0236
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0659 0.0632
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0115 0.0217
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0028 0.0035
Brugia malayi Matrixin family protein 0.002 0.0049 0.0086
Echinococcus multilocularis neuropeptide receptor 0.005 0.0391 0.0485
Schistosoma mansoni protein kinase 0.0064 0.0554 0.0697
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0021 0.0019
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0021 0.0026
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0778 0.0978
Schistosoma mansoni cpg binding protein 0.0033 0.02 0.0251
Schistosoma mansoni sugar transporter 0.0029 0.0157 0.0197
Giardia lamblia Sugar-proton symporter 0.0029 0.0157 0.0346
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0039 0.0274 0.0592
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0028 0.0035
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1101 0.2945
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.08 0.0999
Loa Loa (eye worm) hypothetical protein 0.0039 0.0272 0.0529
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0047 0.0043
Echinococcus multilocularis lysyl tRNA synthetase 0.0046 0.0355 0.044
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0543 0.0676
Mycobacterium ulcerans hypothetical protein 0.0024 0.0099 0.0163
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.0391 0.0485
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus granulosus neuropeptide Y receptor 0.005 0.0391 0.0485
Onchocerca volvulus 0.005 0.0391 0.0686
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0221 0.0429
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1101 0.2945
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.005 0.0391 0.0492
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.005 0.0391 0.0485
Brugia malayi G-protein coupled receptor 0.005 0.0391 0.0766
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0157 0.1426
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.0046 0.0355 0.0694
Brugia malayi neuropeptide F receptor 0.005 0.0391 0.0766
Onchocerca volvulus 0.0029 0.0157 0.0216
Schistosoma mansoni hypothetical protein 0.005 0.0391 0.0492
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0188 0.0362
Schistosoma mansoni lozenge 0.0057 0.0475 0.0597
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0564 0.512
Schistosoma mansoni metabotropic glutamate receptor 0.0137 0.1399 0.1759
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0489 0.0605
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0095 0.0866
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0028 0.0026
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus g protein coupled receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.0045 0.0342 0.0667
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0166 0.0108
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.0391 0.0485
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus granulosus neuropeptide receptor A26 0.005 0.0391 0.0485
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0095 0.0067
Onchocerca volvulus 0.0029 0.0157 0.0216
Brugia malayi beta-NAC-like protein 0.004 0.028 0.0544
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0564 0.512
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0046 0.0355 0.3226
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0099 0.0024
Echinococcus granulosus lysyl tRNA synthetase 0.0046 0.0355 0.044
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0564 0.1466
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Echinococcus granulosus orexin receptor type 2 0.005 0.0391 0.0485
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0062 0.0539 0.0672
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0099 0.0186
Echinococcus multilocularis General substrate transporter 0.0179 0.1881 0.236
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0072 0.0653 0.0815
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0166 0.4204
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0047 0.0044
Leishmania major DNA polymerase eta, putative 0.002 0.0047 0.0428
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0042 0.0303 0.0591
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0564 0.512
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Onchocerca volvulus 0.005 0.0391 0.0686
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.08 0.1005
Onchocerca volvulus 0.0029 0.0157 0.0216
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Schistosoma mansoni neuropeptide receptor 0.005 0.0391 0.0492
Trypanosoma brucei glucose transporter 1E 0.0065 0.0564 0.512
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.0391 0.0485
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0166 0.4204
Loa Loa (eye worm) hypothetical protein 0.002 0.0047 0.0083
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0099 0.0189
Brugia malayi Bromodomain containing protein 0.0078 0.0723 0.1425
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0564 0.1466
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.005 0.0391 0.0492
Brugia malayi neuropeptide F receptor 0.005 0.0391 0.0766
Brugia malayi Matrixin family protein 0.002 0.0049 0.0086
Loa Loa (eye worm) matrixin family protein 0.0044 0.0328 0.0641
Schistosoma mansoni neuropeptide receptor 0.005 0.0391 0.0492
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0047 0.0059
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus multilocularis alpha 1A adrenergic receptor 0.005 0.0391 0.0485
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0265 0.0327
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Onchocerca volvulus Putative transporter 0.0029 0.0157 0.0216
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0042 0.0303 0.0591
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0157 0.019
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.0391 0.0492
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0062 0.0539 0.106
Schistosoma mansoni hypothetical protein 0.005 0.0391 0.0492
Entamoeba histolytica protein kinase, putative 0.0064 0.0554 0.1402
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.0391 0.0485
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0064 0.0555 0.0528
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0099 0.0144
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Schistosoma mansoni metabotropic glutamate receptor 0.008 0.0739 0.0929
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0024 0.0098 0.0116
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0105 0.0125
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0166 0.0138
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0099 0.0189
Plasmodium falciparum phd finger protein, putative 0.0032 0.0188 0.016
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0188 0.0143
Trypanosoma brucei transcription factor BTF3, putative 0.004 0.028 0.2539
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus serotonin receptor 0.005 0.0391 0.0485
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1101 1
Echinococcus granulosus peregrin 0.0034 0.0216 0.0265
Echinococcus granulosus somatostatin receptor 0.005 0.0391 0.0485
Echinococcus multilocularis neuropeptide FF receptor 2 0.005 0.0391 0.0485
Onchocerca volvulus 0.005 0.0391 0.0686
Loa Loa (eye worm) ICD-1 protein 0.004 0.028 0.0544
Onchocerca volvulus 0.005 0.0391 0.0686
Onchocerca volvulus 0.005 0.0391 0.0686
Loa Loa (eye worm) hypothetical protein 0.0051 0.0407 0.0798
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0166 0.0138
Echinococcus granulosus alpha 1A adrenergic receptor 0.005 0.0391 0.0485
Echinococcus multilocularis orexin receptor type 2 0.005 0.0391 0.0485
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0407 0.0798
Trypanosoma brucei glucose transporter 2A 0.0065 0.0564 0.512
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Loa Loa (eye worm) hypothetical protein 0.0453 0.504 1
Leishmania major protein kinase, putative 0.0064 0.0554 0.5034
Echinococcus multilocularis solute carrier family 22 0.0029 0.0157 0.019
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0099 0.0186
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0539 0.0678
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0099 0.0024
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0047 0.0083
Echinococcus granulosus neuropeptide FF receptor 2 0.005 0.0391 0.0485
Toxoplasma gondii protein kinase, putative 0.0589 0.6597 1
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.08 0.1577
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0046 0.0355 0.1622
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Brugia malayi Dopamine receptor 0.005 0.0391 0.0766
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Brugia malayi sulfakinin receptor protein 0.005 0.0391 0.0766
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1101 0.2914
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0099 0.0163
Trypanosoma cruzi hexose transporter 0.0065 0.0564 0.512
Brugia malayi lysyl-tRNA synthetase 0.0046 0.0355 0.0694
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Plasmodium falciparum basic transcription factor 3b, putative 0.004 0.028 0.0252
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni peptide (allatostatin)-like receptor 0.005 0.0391 0.0492
Echinococcus multilocularis tachykinin peptides receptor 99D 0.005 0.0391 0.0485
Schistosoma mansoni neuropeptide receptor 0.005 0.0391 0.0492
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1101 0.2175
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Onchocerca volvulus 0.005 0.0391 0.0686
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0157 0.1426
Onchocerca volvulus 0.0029 0.0157 0.0216
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0047 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0274 0.1118
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0157 0.0296
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.0391 0.0485
Brugia malayi Bromodomain containing protein 0.0034 0.0216 0.0418
Echinococcus granulosus dna polymerase eta 0.002 0.0047 0.0052
Echinococcus granulosus metabotropic glutamate receptor 5 0.0202 0.214 0.2686
Schistosoma mansoni microtubule-associated protein tau 0.0706 0.7953 1
Onchocerca volvulus 0.005 0.0391 0.0686
Brugia malayi phosphofructokinase 0.0111 0.1101 0.2175
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0095 0.0154
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0307 0.038
Schistosoma mansoni protein kinase 0.0064 0.0554 0.0697
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0564 0.1466
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0157 0.0296
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0188 0.016
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0028 0.0044
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0099 0.09
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.1101 0.1378
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni opsin-like receptor 0.005 0.0391 0.0492
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Chlamydia trachomatis lysine--tRNA ligase 0.0046 0.0355 1
Echinococcus granulosus solute carrier family 22 0.0029 0.0157 0.019
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0391 0.0485
Giardia lamblia PHD finger protein 15 0.0032 0.0188 0.0432
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Onchocerca volvulus 0.0029 0.0157 0.0216
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Plasmodium falciparum hexose transporter 0.0208 0.2218 0.2196
Onchocerca volvulus 0.0029 0.0157 0.0216
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0148 0.1528 0.3023
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0307 0.0599
Schistosoma mansoni neuropeptide f receptor 76f 0.005 0.0391 0.0492
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0564 0.512
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Toxoplasma gondii facilitative glucose transporter GT1 0.0208 0.2218 0.3266
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Brugia malayi Dopamine receptor protein 1 0.005 0.0391 0.0766
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0047 0.0052
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0064 0.0555 0.0706
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.0391 0.0492
Onchocerca volvulus 0.005 0.0391 0.0686
Plasmodium falciparum calcium-dependent protein kinase 2 0.0064 0.0555 0.0528
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0027 0.0126 0.0154
Onchocerca volvulus 0.0029 0.0157 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Loa Loa (eye worm) hypothetical protein 0.0051 0.0404 0.0792
Echinococcus granulosus hypothetical protein 0.005 0.0391 0.0485
Echinococcus granulosus dnaJ subfamily B 0.0419 0.464 0.5832
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Schistosoma mansoni biogenic amine receptor 0.005 0.0391 0.0492
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.005 0.0391 0.0766
Leishmania major lysyl-tRNA synthetase, putative 0.0046 0.0355 0.3226
Plasmodium vivax CDK-related protein kinase 6, putative 0.0884 1 1
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Entamoeba histolytica hypothetical protein 0.0024 0.0095 0.0133
Loa Loa (eye worm) sugar transporter 0.0029 0.0157 0.0301
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0047 0.0428
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0047 0.0428
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Brugia malayi Serotonin receptor 0.005 0.0391 0.0766
Leishmania major DNA polymerase kappa, putative 0.002 0.0047 0.0428
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.0391 0.0492
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi putative neuropeptide receptor NPR1 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.005 0.0391 0.0766
Toxoplasma gondii proteasome regulatory subunit 0.0024 0.0098 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0086
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0047 0.0364 0.0458
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0157 0.0301
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0564 0.1466
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Echinococcus granulosus 7tm_1 domain containing protein 0.005 0.0391 0.0485
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0018 0.0031 0.0032
Echinococcus granulosus g protein coupled receptor 0.005 0.0391 0.0485
Brugia malayi G protein-coupled receptor 0.005 0.0391 0.0766
Schistosoma mansoni protein kinase 0.0064 0.0554 0.0697
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni adenoreceptor 0.005 0.0391 0.0492
Loa Loa (eye worm) proteasome 26S subunit 0.0018 0.0031 0.0051
Brugia malayi Cam kinase protein 1 0.0064 0.0554 0.109
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.005 0.0391 0.0766
Plasmodium falciparum mitogen-activated protein kinase 2 0.0337 0.3696 0.3678
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0157 0.019
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.005 0.0391 0.0485
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.028 0.2539
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0186
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0243 0.0299
Brugia malayi CXXC zinc finger family protein 0.0029 0.0158 0.0303
Brugia malayi Hemopexin family protein 0.0028 0.0145 0.0276
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0099 0.0163
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1101 0.1384
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0024 0.0098 0.0183
Echinococcus multilocularis g protein coupled receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) melatonin receptor type 1A 0.005 0.0391 0.0766
Mycobacterium ulcerans sugar transporter 0.0029 0.0157 0.0296
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.1101 0.2861
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.005 0.0391 0.0485
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0166 0.0138
Entamoeba histolytica protein kinase, putative 0.0064 0.0554 0.1402
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0074 0.139
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus peptide allatostatin:somatostatin 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0086
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0105 0.1026 0.1284
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0099 0.09
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0095 0.0067
Schistosoma mansoni sugar transporter 0.0029 0.0157 0.0197
Echinococcus multilocularis g protein coupled receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Trypanosoma brucei unspecified product 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.0391 0.0492
Schistosoma mansoni myosin xvIII 0.005 0.0391 0.0492
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0157 0.1426
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0539 0.0678
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi hypothetical protein 0.0029 0.0157 0.0301
Toxoplasma gondii sugar transporter ST3 0.0029 0.0157 0.0095
Schistosoma mansoni hypothetical protein 0.005 0.0391 0.0492
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Brugia malayi Melatonin receptor type 1A 0.005 0.0391 0.0766
Echinococcus granulosus G protein coupled receptor 139 0.005 0.0391 0.0485
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.005 0.0391 0.0485
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0024 0.0098 0.014
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Leishmania major glucose transporter, lmgt2 0.0065 0.0564 0.512
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.0391 0.0492
Echinococcus multilocularis neuropeptide receptor 0.005 0.0391 0.0485
Plasmodium falciparum calcium-dependent protein kinase 4 0.0064 0.0555 0.0528
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0157 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.2218 0.6021
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0021 0.0019
Echinococcus multilocularis dna polymerase kappa 0.002 0.0047 0.0052
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0554 0.0697
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0062 0.0539 0.1399
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0018 0.0031 0.0284
Onchocerca volvulus 0.0029 0.0157 0.0216
Onchocerca volvulus 0.005 0.0391 0.0686
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0062 0.0539 0.1361
Onchocerca volvulus 0.0029 0.0157 0.0216
Brugia malayi hypothetical protein 0.0125 0.1264 0.2499
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Echinococcus granulosus neuropeptide Y receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) matrixin family protein 0.0048 0.0374 0.0732
Echinococcus granulosus solute carrier family 22 0.0029 0.0157 0.019
Onchocerca volvulus Huntingtin homolog 0.0125 0.1264 0.2434
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0355 0.0753
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0659 0.0632
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0024 0.0098 0.0069
Onchocerca volvulus 0.0029 0.0157 0.0216
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0157 0.0301
Brugia malayi major facilitator superfamily protein 0.0029 0.0157 0.0301
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0047 0.0083
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0564 0.1466
Schistosoma mansoni sugar transporter 0.0029 0.0157 0.0197
Plasmodium vivax lysine--tRNA ligase, putative 0.0046 0.0355 0.0328
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0188 0.0143
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.0391 0.0485
Giardia lamblia Prolyl-tRNA synthetase 0.0062 0.0539 0.1399
Brugia malayi Sugar transporter family protein 0.0208 0.2218 0.4395
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0099 0.0163
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Schistosoma mansoni glucose transport protein 0.0208 0.2218 0.2789
Loa Loa (eye worm) hypothetical protein 0.0453 0.504 1
Echinococcus multilocularis microtubule associated protein 2 0.0706 0.7953 1
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0105 0.0132
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Loa Loa (eye worm) sugar transporter 0.0208 0.2218 0.4395
Loa Loa (eye worm) glutamate receptor 0.0164 0.1705 0.3375
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.0391 0.0485
Echinococcus granulosus dna polymerase kappa 0.002 0.0047 0.0052
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0407 0.0798
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Echinococcus multilocularis dro:myosuppressin receptor 0.005 0.0391 0.0485
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0166 0.0256
Brugia malayi 6-phosphofructokinase 0.0111 0.1101 0.2175
Echinococcus multilocularis serotonin receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0018 0.0031 0.0284
Plasmodium vivax calcium-dependent protein kinase, putative 0.0064 0.0555 0.0528
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Toxoplasma gondii NAC domain-containing protein 0.004 0.028 0.0283
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1101 0.2175
Trichomonas vaginalis conserved hypothetical protein 0.004 0.028 0.0684
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0018 0.0031 0.0284
Schistosoma mansoni histamine h1 receptor 0.005 0.0391 0.0492
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0047 0.0428
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0391 0.0492
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0062 0.0539 0.106
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1101 0.2945
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0564 0.512
Onchocerca volvulus Matrix metalloproteinase homolog 0.0044 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.0032 0.0188 0.0362
Schistosoma mansoni hypothetical protein 0.0028 0.0145 0.0182
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0046 0.0355 0.3226
Trichomonas vaginalis conserved hypothetical protein 0.004 0.028 0.0684
Echinococcus multilocularis biogenic amine (5HT) receptor 0.005 0.0391 0.0485
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0099 0.0163
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Echinococcus multilocularis somatostatin receptor 0.005 0.0391 0.0485
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni bromodomain containing protein 0.0066 0.0585 0.0735
Loa Loa (eye worm) hypothetical protein 0.0202 0.214 0.4241
Loa Loa (eye worm) hypothetical protein 0.0064 0.0554 0.109
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0047 0.0428
Schistosoma mansoni opsin-like receptor 0.005 0.0391 0.0492
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0166 0.0108
Echinococcus granulosus neuropeptide receptor 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0064 0.0554 0.069
Trypanosoma brucei sugar transporter, putative 0.0029 0.0157 0.1426
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.005 0.0391 0.0766
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.005 0.0391 0.0485
Echinococcus granulosus fmrfamide receptor 0.005 0.0391 0.0485
Echinococcus multilocularis zinc finger protein 0.0022 0.007 0.0081
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0095 0.006
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0157 0.019
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Leishmania major basic transcription factor 3a, putative 0.004 0.028 0.2539
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0158
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Brugia malayi hypothetical protein 0.0453 0.504 1
Schistosoma mansoni glucose transporter 0.0029 0.0157 0.0197
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0028 0.0028
Echinococcus multilocularis serotonin receptor 0.005 0.0391 0.0485
Brugia malayi Sugar transporter family protein 0.0029 0.0157 0.0301
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0307 0.0386
Echinococcus multilocularis neuropeptide s receptor 0.005 0.0391 0.0485
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Schistosoma mansoni cpg binding protein 0.0029 0.0158 0.0199
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.08 0.0999
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0157 0.0301
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Onchocerca volvulus 0.005 0.0391 0.0686
Loa Loa (eye worm) hypothetical protein 0.0085 0.08 0.1577
Onchocerca volvulus Poor gastrulation protein homolog 0.0027 0.0126 0.0154
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni biogenic amine receptor 0.005 0.0391 0.0492
Onchocerca volvulus 0.0029 0.0157 0.0216
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.005 0.0391 0.0492
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0072 0.0653 0.0815
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0208 0.2218 0.2784
Echinococcus granulosus metabotropic glutamate receptor 2 0.0137 0.1399 0.1753
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Schistosoma mansoni neuropeptide receptor 0.005 0.0391 0.0492
Brugia malayi GnHR receptor homolog 0.005 0.0391 0.0766
Echinococcus granulosus tachykinin peptides receptor 99D 0.005 0.0391 0.0485
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Brugia malayi 6-phosphofructokinase 0.0111 0.1101 0.2175
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Brugia malayi gonadotropin-releasing hormone receptor 2 0.005 0.0391 0.0766
Giardia lamblia Fructose-bisphosphate aldolase 0.0334 0.3663 1
Loa Loa (eye worm) phosphofructokinase 0.0111 0.1101 0.2175
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi larval opioid receptor 0.005 0.0391 0.0766
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0062 0.0539 0.0672
Plasmodium vivax hexose transporter 0.0208 0.2218 0.2196
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1101 1
Onchocerca volvulus 0.0024 0.0099 0.01
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.058 0.1141
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0564 0.512
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0186
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.005 0.0391 0.0492
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.0391 0.0766
Leishmania major glucose transporter, lmgt3 0.0065 0.0564 0.512
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.028 0.2539
Echinococcus multilocularis solute carrier family 22 0.0029 0.0157 0.019
Schistosoma mansoni hypothetical protein 0.0208 0.2218 0.2789
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0086
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi Sugar transporter family protein 0.0029 0.0157 0.0301
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0024 0.0098 0.0183
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0307 0.0386
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0157 0.0322
Plasmodium falciparum calcium-dependent protein kinase 1 0.0064 0.0555 0.0528
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0391 0.0485
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Brugia malayi Metabotropic glutamate receptor precursor. 0.0164 0.1705 0.3375
Brugia malayi Matrixin family protein 0.002 0.0049 0.0086
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Echinococcus granulosus General substrate transporter 0.0179 0.1881 0.236
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.0391 0.0766
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0095 0.2046
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.002 0.0049 0.0062
Echinococcus multilocularis transcription factor btf3 0.004 0.028 0.0345
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0188 0.023
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Entamoeba histolytica hypothetical protein 0.0046 0.0355 0.0852
Plasmodium falciparum calcium-dependent protein kinase 3 0.0064 0.0555 0.0528
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0554 0.144
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0064 0.0555 0.0706
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.1101 0.6276
Echinococcus granulosus neuropeptides capa receptor 0.005 0.0391 0.0485
Echinococcus multilocularis G protein coupled receptor 139 0.005 0.0391 0.0485
Brugia malayi Matrixin family protein 0.002 0.0049 0.0086
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0186 0.1963 0.2469
Echinococcus granulosus zinc finger protein 0.0022 0.007 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Brugia malayi hypothetical protein 0.0029 0.0157 0.0301
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.0042 0.0303 0.0591
Schistosoma mansoni hypothetical protein 0.005 0.0391 0.0492
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0047 0.0043
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.005 0.0391 0.0492
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Echinococcus granulosus g protein coupled receptor 0.005 0.0391 0.0485
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0047 0.0428
Entamoeba histolytica hypothetical protein 0.004 0.028 0.0643
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0064 0.0554 0.109
Schistosoma mansoni hypothetical protein 0.0021 0.0063 0.0079
Onchocerca volvulus 0.005 0.0391 0.0686
Echinococcus multilocularis peregrin 0.0034 0.0216 0.0265
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0018 0.0031 0.0032
Mycobacterium ulcerans hydrolase 0.0024 0.0099 0.0162
Toxoplasma gondii sugar transporter ST2 0.0029 0.0157 0.0095
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.005 0.0391 0.0766
Echinococcus multilocularis GPCR, family 3, C terminal 0.0027 0.0126 0.0151
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus granulosus GPCR family 3 C terminal 0.0027 0.0126 0.0151
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni biogenic amine receptor 0.005 0.0391 0.0492
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Plasmodium falciparum calcium-dependent protein kinase 5 0.0064 0.0555 0.0528
Onchocerca volvulus Huntingtin homolog 0.0125 0.1264 0.2434
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.005 0.0391 0.0492
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0064 0.0554 0.109
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi metabotropic glutamate receptor type 2 0.008 0.0739 0.1456
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi Bromodomain containing protein 0.0039 0.0271 0.0527
Echinococcus granulosus neuropeptide receptor 0.005 0.0391 0.0485
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0289 0.071
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0509 0.0633
Loa Loa (eye worm) runx1 0.0057 0.0475 0.0931
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0355 0.0753
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0186
Brugia malayi Receptor family ligand binding region containing protein 0.0042 0.0303 0.0591
Brugia malayi G-protein coupled receptor 0.005 0.0391 0.0766
Echinococcus granulosus allatostatin A receptor 0.005 0.0391 0.0485
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0028 0.0028
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0064 0.0554 0.109
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Onchocerca volvulus 0.0029 0.0157 0.0216
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0337 0.3696 0.3678
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1101 0.1384
Toxoplasma gondii lysine-tRNA ligase 0.0046 0.0355 0.04
Schistosoma mansoni DNA polymerase eta 0.002 0.0047 0.0059
Onchocerca volvulus 0.005 0.0391 0.0686
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.0391 0.0485
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0564 0.1466
Mycobacterium leprae PROBABLE HYDROLASE 0.0024 0.0099 0.0023
Treponema pallidum fructose-bisphosphate aldolase 0.0334 0.3663 1
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0105 0.0125
Onchocerca volvulus 0.0029 0.0157 0.0216
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni alpha-1 adrenergic receptor 0.005 0.0391 0.0492
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0047 0.0083
Schistosoma mansoni growth hormone secretagogue receptor 0.005 0.0391 0.0492
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0543 0.0676
Onchocerca volvulus Alhambra homolog 0.0032 0.0188 0.0279
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0064 0.0555 0.0528
Plasmodium vivax basic transcription factor 3b, putative 0.004 0.028 0.0252
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0047 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0157 0.0296
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1101 0.2945
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0024 0.0099 0.0188
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0099 0.0144
Echinococcus granulosus solute carrier family 22 0.0029 0.0157 0.019
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Echinococcus granulosus microtubule associated protein 2 0.0706 0.7953 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0391 0.0492
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0538 0.0676
Onchocerca volvulus 0.0028 0.0145 0.0192
Schistosoma mansoni glucose transport protein 0.0208 0.2218 0.2789
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0166 0.0328
Echinococcus granulosus transcription factor btf3 0.004 0.028 0.0345
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Schistosoma mansoni hypothetical protein 0.0032 0.0188 0.0236
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0157 1
Giardia lamblia DINP protein human, muc B family 0.002 0.0047 0.0044
Schistosoma mansoni sugar transporter 0.0029 0.0157 0.0197
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0332 0.0411
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0095 0.018
Loa Loa (eye worm) glutamate receptor 0.0064 0.0561 0.1104
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0099 0.0163
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Brugia malayi Serotonin receptor 0.005 0.0391 0.0766
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0226 0.2056
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0007
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0027 0.0126 0.0239
Brugia malayi major facilitator superfamily protein 0.0029 0.0157 0.0301
Giardia lamblia Hexose transporter 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.0042 0.03 0.0584
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.1101 0.2472
Brugia malayi follicle stimulating hormone receptor 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0166 0.0108
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0157 0.1426
Echinococcus granulosus sex peptide receptor 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Plasmodium falciparum lysine--tRNA ligase 0.0046 0.0355 0.0328
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0064 0.0554 0.5034
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0337 0.3696 0.5538
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni transcription factor btf3 0.004 0.028 0.0351
Echinococcus multilocularis allatostatin A receptor 0.005 0.0391 0.0485
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0024 0.0098 0.0069
Leishmania major glucose transporter, lmgt1 0.0065 0.0564 0.512
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0355 0.0446
Brugia malayi Dopamine receptor protein 2 0.005 0.0391 0.0766
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0024 0.0098 0.0183
Brugia malayi RE15519p 0.005 0.0391 0.0766
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0035 0.0221 0.0429
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0074 0.0105
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0105 0.1026 0.1284
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Onchocerca volvulus 0.0029 0.0158 0.0219
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0099 0.0186
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0047 0.0428
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0274 0.0592
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0024 0.0098 0.0116
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0391 0.0485
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0047 0.0428
Echinococcus multilocularis solute carrier family 22 0.0029 0.0157 0.019
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0355 0.0446
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0163 0.1697 1
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0332 0.0411
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Toxoplasma gondii sugar transporter ST1 0.0029 0.0157 0.0095
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Echinococcus granulosus g-protein coupled receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0407 0.0798
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0166 0.037
Giardia lamblia Lysyl-tRNA synthetase 0.0046 0.0355 0.0892
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.005 0.0391 0.0766
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0157 0.0197
Echinococcus multilocularis dna polymerase eta 0.002 0.0047 0.0052
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0355 0.0892
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0099 0.0144
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0185
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Brugia malayi PHD-finger family protein 0.0032 0.0188 0.0362
Onchocerca volvulus 0.005 0.0391 0.0686
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Echinococcus multilocularis dnaJ subfamily B 0.0419 0.464 0.5832
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus dro:myosuppressin receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.0239
Plasmodium vivax sugar transporter, putative 0.0029 0.0157 0.0129
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.005 0.0391 0.0492
Plasmodium falciparum protein kinase 7 0.0589 0.6597 0.6587
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus neuropeptide s receptor 0.005 0.0391 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.004 0.028 0.0684
Echinococcus multilocularis neuropeptide receptor A26 0.005 0.0391 0.0485
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0099 0.0163
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0021 0.0026
Brugia malayi AKH receptor 0.005 0.0391 0.0766
Brugia malayi Serotonin/octopamine receptor family protein 7 0.005 0.0391 0.0766
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Leishmania major hypothetical protein, conserved 0.0029 0.0157 0.1426
Echinococcus multilocularis Protein lozenge 0.0057 0.0475 0.059
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.0391 0.0766
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0157 0.1426
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0243 0.0299
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0066 0.012
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0064 0.0555 0.0528
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis fmrfamide receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0158 0.0303
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0063 0.0114
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1101 0.2914
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0047 0.0428
Brugia malayi jmjC domain containing protein 0.0105 0.1026 0.2027
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0166 0.0138
Onchocerca volvulus 0.005 0.0391 0.0686
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0163 0.1697 0.3848
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0659 0.0866
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.1101 0.1378
Onchocerca volvulus 0.0029 0.0157 0.0216
Onchocerca volvulus Neuropeptide F receptor homolog 0.005 0.0391 0.0686
Brugia malayi hypothetical protein 0.0029 0.0157 0.0301
Echinococcus granulosus solute carrier family 22 0.0029 0.0157 0.019
Brugia malayi jmjC domain containing protein 0.0042 0.0307 0.0599
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus multilocularis solute carrier family 22 0.0029 0.0157 0.019
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0047 0.0059
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0024 0.0099 0.0185
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0564 0.512
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1101 0.2914
Echinococcus granulosus 7TM GPCR rhodopsin 0.005 0.0391 0.0485
Loa Loa (eye worm) TYRA-2 protein 0.005 0.0391 0.0766
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Onchocerca volvulus 0.0029 0.0157 0.0216
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0062 0.0539 0.2771
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.1101 1
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0095 0.0154
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0157 0.019
Brugia malayi Tachykinin-like peptides receptor 99D 0.005 0.0391 0.0766
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0509 0.0633
Loa Loa (eye worm) hypothetical protein 0.0072 0.0653 0.1286
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0018 0.0031 0.0284
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Onchocerca volvulus 0.005 0.0391 0.0686
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.005 0.0391 0.0485
Schistosoma mansoni opsin-like receptor 0.005 0.0391 0.0492
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0391 0.0485
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0157 0.0095
Schistosoma mansoni zinc finger protein 0.0022 0.007 0.0088
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0047 0.0069
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0202 0.214 0.2686
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0163 0.1697 0.3864
Echinococcus granulosus cpg binding protein 0.0033 0.02 0.0245
Echinococcus granulosus thyrotropin releasing hormone receptor 0.005 0.0391 0.0485
Brugia malayi PHD-finger family protein 0.0027 0.0133 0.0252
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0095 0.0866
Entamoeba histolytica transcription factor BTF3, putative 0.004 0.028 0.0643
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Schistosoma mansoni cpg binding protein 0.0033 0.02 0.0251
Loa Loa (eye worm) hypothetical protein 0.0062 0.0539 0.106
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.0391 0.0485
Echinococcus granulosus neuropeptides capa receptor 0.005 0.0391 0.0485
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.1101 0.2492

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 0.4 nM Inhibition of human recombinant soluble epoxide hydrolase by fluorescence assay ChEMBL. 20812725
IC50 (binding) = 0.4 nM Fluorescent Based Assay BINDINGDB. No reference
IC50 (binding) = 0.7 nM Inhibition of mouse recombinant soluble epoxide hydrolase by fluorescence assay ChEMBL. 20812725
IC50 (binding) = 0.7 nM Fluorescent Based Assay BINDINGDB. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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