Detailed information for compound 1318698

Basic information

Technical information
  • TDR Targets ID: 1318698
  • Name: N-[(3R,4R,5Z,11S,12R,13Z)-4,12-dimethyl-11-[( 4-methylphenyl)sulfonylamino]-8,16-dioxo-1,9- dioxacyclohexadeca-5,13-dien-3-yl]-4-methylbe nzenesulfonamide
  • MW: 618.761 | Formula: C30H38N2O8S2
  • H donors: 2 H acceptors: 6 LogP: 4.66 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 2
  • SMILES: C[C@@H]1/C=C\CC(=O)OC[C@@H](NS(=O)(=O)c2ccc(cc2)C)[C@@H](/C=C\CC(=O)OC[C@@H]1NS(=O)(=O)c1ccc(cc1)C)C
  • InChi: 1S/C30H38N2O8S2/c1-21-11-15-25(16-12-21)41(35,36)31-27-19-39-29(33)10-6-8-24(4)28(20-40-30(34)9-5-7-23(27)3)32-42(37,38)26-17-13-22(2)14-18-26/h5-8,11-18,23-24,27-28,31-32H,9-10,19-20H2,1-4H3/b7-5-,8-6-/t23-,24-,27-,28+/m1/s1
  • InChiKey: LNXPTLKVQXCROH-CWXGCFCRSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[(3R,4R,5Z,11S,12R,13Z)-4,12-dimethyl-11-[(4-methylphenyl)sulfonylamino]-8,16-dioxo-1,9-dioxacyclohexadeca-5,13-dien-3-yl]-4-methyl-benzenesulfonamide
  • N-[(3R,4R,5Z,11S,12R,13Z)-8,16-diketo-4,12-dimethyl-11-[(4-methylphenyl)sulfonylamino]-1,9-dioxacyclohexadeca-5,13-dien-3-yl]-4-methyl-benzenesulfonamide

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 Starlite/ChEMBL No references
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania major cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans cytochrome P450 556 Get druggable targets OG5_126554 All targets in OG5_126554
Brugia malayi Cytochrome P450 family protein Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans closely related to C.maltosa N-alkane-inducible cytochrome P-450, alkane hydroxylating monooxygenase CYP52A3-b aka P450Alk1A (BA Get druggable targets OG5_126554 All targets in OG5_126554
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to C.maltosa N-alkane inducible cytochrome P-450, ALK8 CYP52A11 Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma cruzi cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani cytochrome p450-like protein Get druggable targets OG5_126554 All targets in OG5_126554
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) CYP4Cod1 Get druggable targets OG5_126554 All targets in OG5_126554
Trypanosoma congolense cytochrome P450, putative Get druggable targets OG5_126554 All targets in OG5_126554
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans cytochrome P450 56 Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) hypothetical protein Get druggable targets OG5_126554 All targets in OG5_126554
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Brugia malayi cytochrome P450 cytochrome P450, family 3, subfamily A, polypeptide 4 502 aa 492 aa 24.2 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0044 0.0063
Trypanosoma brucei transcription factor BTF3, putative 0.0069 0.0325 0.1143
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0085 0.0416 0.0603
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0022 0.0042 0.0042
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0021 0.003
Loa Loa (eye worm) thrombospondin type 1 domain-containing protein 0.1161 0.6895 1
Schistosoma mansoni ap endonuclease 0.0023 0.0044 0.0063
Echinococcus granulosus dna polymerase kappa 0.0019 0.0021 0.0038
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0044 0.0063
Loa Loa (eye worm) hypothetical protein 0.0538 0.3144 0.456
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0061 0.0214
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0177 0.032
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0061 0.0111
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0021 0.003
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0068
Brugia malayi hypothetical protein 0.005 0.0208 0.0301
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0047 0.0085
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0044 0.1049
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0047 0.0068
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0488 0.2845 0.4126
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0023 0.0047 0.0068
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0047 0.0047
Brugia malayi nuclear hormone receptor 0.0023 0.0047 0.0068
Trypanosoma brucei PAB1-binding protein , putative 0.005 0.0208 0.073
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0023 0.0047 0.0047
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0085 0.0416 0.0751
Schistosoma mansoni nuclear hormone receptor 0.0023 0.0047 0.0068
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0208 0.4989
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0323 0.1852 0.6509
Onchocerca volvulus GPI ethanolamine phosphate transferase 2 homolog 0.0085 0.0416 0.0539
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0488 0.2845 1
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0348 0.1931
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0068
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Giardia lamblia Fructose-bisphosphate aldolase 0.0615 0.3612 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0348 0.0629
Entamoeba histolytica hypothetical protein 0.0035 0.012 0.0275
Onchocerca volvulus GPI ethanolamine phosphate transferase 3 homolog 0.0085 0.0416 0.0539
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0301 0.1717 1
Loa Loa (eye worm) type I phosphodiesterase/nucleotide pyrophosphatase 0.0085 0.0416 0.0603
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0023 0.0047 0.0085
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0281 0.0408
Loa Loa (eye worm) jmjC domain-containing protein 0.0058 0.0256 0.0371
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0047 0.0068
Loa Loa (eye worm) hypothetical protein 0.005 0.0208 0.0301
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0256 0.0371
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0068
Loa Loa (eye worm) ICD-1 protein 0.0069 0.0325 0.0471
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0281 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0023 0.0047 0.0068
Mycobacterium ulcerans hypothetical protein 0.0085 0.0416 0.233
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0318 0.0461
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0047 0.0068
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0021 0.0021
Brugia malayi hypothetical protein 0.0157 0.085 0.1232
Trypanosoma cruzi endonuclease G, putative 0.0323 0.1852 0.6509
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0177 0.032
Plasmodium falciparum basic transcription factor 3b, putative 0.0069 0.0325 0.7814
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0348 0.0348
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0044 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0023 0.0047 0.0068
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0538 0.3144 0.456
Trypanosoma brucei unspecified product 0.0019 0.0021 0.0074
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0074
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0171 0.0926
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0068
Toxoplasma gondii NAC domain-containing protein 0.0069 0.0325 0.1756
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0023 0.0047 0.0047
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0085 0.0416 0.0603
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0061 0.0329
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.3144
Loa Loa (eye worm) acetyltransferase 0.0149 0.0807 0.117
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3612 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0488 0.2845 0.5134
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 7 homolog 0.0085 0.0416 0.0539
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0488 0.2845 0.7865
Loa Loa (eye worm) hypothetical protein 0.0085 0.0416 0.0603
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0058 0.0256 0.0462
Schistosoma mansoni steroid hormone receptor ad4bp 0.0023 0.0047 0.0068
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0488 0.2845 1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0023 0.0047 0.0047
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.3144
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0102 0.0523 0.0944
Onchocerca volvulus 0.0538 0.3144 0.4523
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0044 0.0063
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0615 0.3612 1
Schistosoma mansoni hypothetical protein 0.0085 0.0416 0.0603
Onchocerca volvulus 0.1161 0.6895 1
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0044 0.0133
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0348 0.1931
Echinococcus granulosus neuropeptide s receptor 0.0936 0.5542 1
Schistosoma mansoni thyroid hormone receptor 0.0023 0.0047 0.0068
Toxoplasma gondii LsmAD domain-containing protein 0.005 0.0208 0.1121
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0348 0.0505
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0023 0.0047 0.0068
Brugia malayi hypothetical protein 0.0035 0.012 0.0174
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0177 0.0257
Brugia malayi Type I phosphodiesterase / nucleotide pyrophosphatase family protein 0.0538 0.3144 0.456
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3612 1
Schistosoma mansoni DNA polymerase eta 0.0044 0.0172 0.0249
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Leishmania major ethanolamine phosphotransferase, putative 0.0085 0.0416 0.1462
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0281 0.0281
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0325 0.0847
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0068 0.0318 0.0827
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0044 0.0079
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.5674
Echinococcus multilocularis ecdysone induced protein 78C 0.0023 0.0047 0.0047
Echinococcus multilocularis Alkaline phosphatase, core domain 0.0085 0.0416 0.0416
Brugia malayi nuclear receptor NHR-88 0.0023 0.0047 0.0068
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0149 0.0807 0.117
Echinococcus granulosus ecdysone induced protein 78C 0.0023 0.0047 0.0085
Plasmodium vivax basic transcription factor 3b, putative 0.0069 0.0325 1
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0149 0.0807 0.0807
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0023 0.0047 0.0068
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0068
Brugia malayi hypothetical protein 0.0085 0.0416 0.0603
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0488 0.2845 0.2845
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0023 0.0047 0.0068
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0023 0.0047 0.0047
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0102 0.0523 0.0523
Schistosoma mansoni retinoic acid receptor RXR 0.0326 0.1868 0.271
Schistosoma mansoni jumonji domain containing protein 0.0058 0.0256 0.0371
Echinococcus multilocularis lysine specific demethylase 5A 0.0058 0.0256 0.0256
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0023 0.0047 0.0085
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Onchocerca volvulus GPI ethanolamine phosphate transferase 1 homolog 0.0085 0.0416 0.0539
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0177 0.0177
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0021 0.0074
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0102 0.0523 0.0523
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0325 0.0847
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0061 0.0214
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.5674
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0023 0.0047 0.0068
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0031 0.0093 0.0502
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0044 0.0133
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0177 0.0257
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0023 0.0047 0.0085
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Brugia malayi hypothetical protein 0.0085 0.0416 0.0603
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0538 0.3144 0.456
Schistosoma mansoni hypothetical protein 0.0356 0.2051 0.2974
Entamoeba histolytica hypothetical protein 0.0035 0.012 0.0275
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0044 0.0063
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0281 0.0408
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Brugia malayi acetyltransferase, GNAT family protein 0.0149 0.0807 0.117
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0023 0.0047 0.0068
Brugia malayi Steroid receptor seven-up type 2 0.0023 0.0047 0.0068
Trypanosoma cruzi endonuclease G, putative 0.0323 0.1852 0.6509
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.5674
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0325 0.0847
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0021 0.0038
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0061 0.0214
Plasmodium vivax ataxin-2 like protein, putative 0.005 0.0208 0.6385
Plasmodium falciparum ataxin-2 like protein, putative 0.005 0.0208 0.4989
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Loa Loa (eye worm) hypothetical protein 0.0453 0.2635 0.3822
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3612 1
Leishmania major hypothetical protein, conserved 0.005 0.0208 0.073
Brugia malayi AEL166Cp 0.0085 0.0416 0.0603
Schistosoma mansoni coup transcription factor 0.0023 0.0047 0.0068
Trypanosoma brucei DNA polymerase eta, putative 0.0044 0.0172 0.0603
Trypanosoma cruzi DNA polymerase eta, putative 0.0031 0.0093 0.0327
Echinococcus granulosus geminin 0.0356 0.2051 0.3701
Schistosoma mansoni hypothetical protein 0.0022 0.0042 0.0061
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0058 0.0256 0.0256
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0061 0.0111
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0023 0.0047 0.0068
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0281 0.0408
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.012 0.012
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3612 1
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0281 0.0408
Echinococcus granulosus transferase 0.0085 0.0416 0.0751
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0348 0.1931
Echinococcus granulosus neuropeptide receptor A26 0.0936 0.5542 1
Echinococcus granulosus FTZ F1 alpha 0.0023 0.0047 0.0085
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0023 0.0047 0.0085
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0023 0.0047 0.0068
Schistosoma mansoni transcription factor btf3 0.0069 0.0325 0.0471
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0047 0.0068
Entamoeba histolytica hypothetical protein 0.0069 0.0325 0.0847
Loa Loa (eye worm) hypothetical protein 0.0085 0.0416 0.0603
Schistosoma mansoni hypothetical protein 0.0356 0.2051 0.2974
Entamoeba histolytica hypothetical protein 0.0035 0.012 0.0275
Echinococcus multilocularis neuropeptide receptor A26 0.0936 0.5542 0.5542
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0281 0.0408
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0023 0.0047 0.0068
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0085 0.0416 0.0416
Schistosoma mansoni RAR-like nuclear receptor 0.0023 0.0047 0.0068
Schistosoma mansoni hypothetical protein 0.0035 0.012 0.0174
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.3144
Trypanosoma brucei endonuclease G, putative 0.0323 0.1852 0.6509
Plasmodium falciparum flap endonuclease 1 0.0026 0.0061 0.1463
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0348 0.0505
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0453 0.2635 0.4755
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0044 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0023 0.0047 0.0068
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0313 0.1794 0.1794
Giardia lamblia Phosphatidylinositol-glycan biosynthesis, class O protein 0.0085 0.0416 0.11
Echinococcus multilocularis thyroid hormone receptor alpha 0.0023 0.0047 0.0047
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0074
Echinococcus multilocularis neuropeptide s receptor 0.0936 0.5542 0.5542
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0538 0.3144 0.456
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0325 0.1143
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0021 0.003
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0023 0.0047 0.0068
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0523 0.0759
Echinococcus multilocularis dna polymerase eta 0.0044 0.0172 0.0172
Brugia malayi endonuclease G, mitochondrial precursor 0.0323 0.1852 0.2685
Brugia malayi Flap endonuclease-1 0.0026 0.0061 0.0088
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0301 0.1717 1
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0488 0.2845 0.4126
Loa Loa (eye worm) hypothetical protein 0.0068 0.0318 0.0461
Trypanosoma brucei endonuclease G, putative 0.0323 0.1852 0.6509
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0023 0.0047 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0023 0.0047 0.0068
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0348 0.1882
Leishmania major DNA polymerase eta, putative 0.0031 0.0093 0.0327
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0021 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0058 0.0256 0.0371
Entamoeba histolytica hypothetical protein 0.0035 0.012 0.0275
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0177 0.0257
Treponema pallidum fructose-bisphosphate aldolase 0.0615 0.3612 1
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0348 0.1225
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0044 0.0153
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0085 0.0416 0.11
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0023 0.0047 0.0068
Loa Loa (eye worm) hypothetical protein 0.0044 0.0172 0.0249
Toxoplasma gondii DNA/RNA non-specific endonuclease 0.0323 0.1852 1
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0068
Loa Loa (eye worm) hypothetical protein 0.0085 0.0416 0.0603
Brugia malayi RNA binding protein 0.0062 0.0281 0.0408
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0149 0.0358
Echinococcus multilocularis Endonuclease G 0.0323 0.1852 0.1852
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.012 0.0174
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0061 0.0061
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0023 0.0047 0.0068
Echinococcus granulosus histone acetyltransferase KAT2B 0.0145 0.0781 0.141
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3612 1
Brugia malayi TAR-binding protein 0.0062 0.0281 0.0408
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0023 0.0047 0.0068
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0171 0.0419
Echinococcus multilocularis transcription factor Dp 1 0.0282 0.1608 0.1608
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.3144
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0488 0.2845 0.4126
Loa Loa (eye worm) steroid hormone receptor 0.0023 0.0047 0.0068
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0281 0.0408
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0488 0.2845 1
Brugia malayi hypothetical protein 0.0032 0.0101 0.0147
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0023 0.0047 0.0068
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0523 0.0759
Echinococcus multilocularis geminin 0.0356 0.2051 0.2051
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0281 0.0408
Loa Loa (eye worm) hypothetical protein 0.0157 0.085 0.1232
Schistosoma mansoni hypothetical protein 0.0085 0.0416 0.0603
Leishmania major DNA polymerase eta, putative 0.0044 0.0172 0.0603
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.3144
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0023 0.0044 0.5
Loa Loa (eye worm) hypothetical protein 0.0538 0.3144 0.456
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0044 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3612 1
Plasmodium falciparum GPI ethanolamine phosphate transferase 3, putative 0.0085 0.0416 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0326 0.1868 0.3372
Leishmania major basic transcription factor 3a, putative 0.0069 0.0325 0.1143
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3612 1
Brugia malayi ImpB/MucB/SamB family protein 0.0044 0.0172 0.0249
Echinococcus multilocularis transferase 0.0085 0.0416 0.0416
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0068
Brugia malayi beta-NAC-like protein 0.0069 0.0325 0.0471
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0044 0.0153
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0023 0.0047 0.0047
Echinococcus granulosus transcription factor btf3 0.0069 0.0325 0.0587
Onchocerca volvulus Ectonucleotide pyrophosphatase\/phosphodiesterase family member 6 homolog 0.0085 0.0416 0.0539
Echinococcus multilocularis transcription factor btf3 0.0069 0.0325 0.0325
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0068 0.0318 0.0461
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0044 0.0153
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0061 0.1873
Toxoplasma gondii exonuclease III APE 0.0023 0.0044 0.0236
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0023 0.0047 0.0068
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0348 0.1931
Leishmania major endonuclease G, putative 0.0323 0.1852 0.6509
Schistosoma mansoni hypothetical protein 0.1161 0.6895 1
Onchocerca volvulus 0.0157 0.085 0.1172
Echinococcus granulosus dna polymerase eta 0.0044 0.0172 0.031
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0023 0.0047 0.0085
Brugia malayi Thrombospondin type 1 domain containing protein 0.1161 0.6895 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0044 0.1342
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0061 0.0088
Brugia malayi jmjC domain containing protein 0.0058 0.0256 0.0371
Loa Loa (eye worm) RNA binding protein 0.0062 0.0281 0.0408
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.5674
Schistosoma mansoni ap endonuclease 0.0023 0.0044 0.0063
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0022 0.0042 0.0075
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0177 0.0257
Echinococcus multilocularis ectonucleotide 0.0453 0.2635 0.2635
Echinococcus granulosus transcription factor Dp 1 0.0282 0.1608 0.2901
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0149 0.0358
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0208 0.073
Trypanosoma cruzi transcription factor btf3, putative 0.0069 0.0325 0.1143
Entamoeba histolytica transcription factor BTF3, putative 0.0069 0.0325 0.0847
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0615 0.3612 1
Loa Loa (eye worm) hypothetical protein 0.0085 0.0416 0.0603
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0453 0.2635 0.2635
Trypanosoma cruzi PAB1-binding protein , putative 0.005 0.0208 0.073
Loa Loa (eye worm) hypothetical protein 0.0538 0.3144 0.456
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0023 0.0047 0.0068
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.3144
Toxoplasma gondii melibiase subfamily protein 0.0102 0.0523 0.2825
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0177 0.0257
Schistosoma mansoni hypothetical protein 0.0085 0.0416 0.0603
Trypanosoma brucei endonuclease G, putative 0.0323 0.1852 0.6509
Echinococcus multilocularis FTZ F1 alpha 0.0023 0.0047 0.0047
Echinococcus granulosus Endonuclease G 0.0323 0.1852 0.3342
Trypanosoma cruzi DNA polymerase eta, putative 0.0044 0.0172 0.0603
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0523 0.0759
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0488 0.2845 1
Schistosoma mansoni endonuclease related 0.0323 0.1852 0.2685
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0301 0.1717 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.012 0.0216
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0021 0.0021
Schistosoma mansoni hypothetical protein 0.0085 0.0416 0.0603
Echinococcus granulosus flap endonuclease 1 0.0026 0.0061 0.011
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0171 0.0926
Echinococcus multilocularis gpi ethanolamine phosphate transferase 1 0.0085 0.0416 0.0416
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0023 0.0047 0.0068
Echinococcus multilocularis gpi ethanolamine phosphate transferase 3 0.0085 0.0416 0.0416
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0044 0.0153
Schistosoma mansoni flap endonuclease-1 0.0023 0.0046 0.0067
Echinococcus granulosus lysine specific demethylase 5A 0.0058 0.0256 0.0462
Schistosoma mansoni ectonucleotide pyrophosphatase/phosphodiesterase 0.0538 0.3144 0.456
Leishmania major DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0171 0.0419
Loa Loa (eye worm) hypothetical protein 0.0023 0.0047 0.0068
Leishmania major DNA/RNA non-specific endonuclease-like protein 0.0323 0.1852 0.6509
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0061 0.0111
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0023 0.0047 0.0068
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0021 0.0074
Echinococcus granulosus ectonucleotide pyrophosphatase:phosphodiesterase 0.0538 0.3144 0.5674
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Echinococcus multilocularis ectonucleotide pyrophosphatase:phosphodiesterase 0.0085 0.0416 0.0416
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0177 0.0177
Brugia malayi steroid hormone receptor 0.0023 0.0047 0.0068
Brugia malayi ecdysteroid receptor 0.0023 0.0047 0.0068
Trypanosoma brucei GPI ethanolamine phosphate transferase 3, putative 0.0085 0.0416 0.1462
Entamoeba histolytica phosphatidylinositol-glycan biosynthesis class O protein, putative 0.0085 0.0416 0.11
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0171 0.5274
Brugia malayi jmjC domain containing protein 0.0058 0.0256 0.0371
Onchocerca volvulus 0.0538 0.3144 0.4523
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0615 0.3612 1
Echinococcus granulosus ectonucleotide 0.0453 0.2635 0.4755
Trypanosoma cruzi DNA/RNA non-specific endonuclease protein-like, putative 0.0323 0.1852 0.6509
Echinococcus granulosus gpi ethanolamine phosphate transferase 3 0.0085 0.0416 0.0751
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0021 0.0074
Brugia malayi Melibiase family protein 0.0068 0.0318 0.0461
Echinococcus granulosus tar DNA binding protein 0.0062 0.0281 0.0508
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0102 0.0523 0.0759
Brugia malayi Nuclear hormone receptor-like 1 0.0023 0.0047 0.0068
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0171 0.0309
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0149 0.3591
Brugia malayi photoreceptor-specific nuclear receptor 0.0023 0.0047 0.0068

Activities

Activity type Activity value Assay description Source Reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
AC50 (functional) = 3.16227766 uM PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active ChEMBL. No reference
Potency (ADMET) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Activators of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (ADMET) = 3.1623 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Substrates of Cytochrome P450 3A4. (Class of assay: confirmatory) [Related pubchem assays: 410 ] ChEMBL. No reference
Potency (functional) 7.0795 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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