Detailed information for compound 1361077

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 229.253 | Formula: C9H11NO4S
  • H donors: 2 H acceptors: 3 LogP: 0.68 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: Oc1ccc(cc1)C1CCOS(=O)(=O)N1
  • InChi: 1S/C9H11NO4S/c11-8-3-1-7(2-4-8)9-5-6-14-15(12,13)10-9/h1-4,9-11H,5-6H2
  • InChiKey: GGBKNTQDZLPWHD-UHFFFAOYSA-N  

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens APEX nuclease (multifunctional DNA repair enzyme) 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Cryptosporidium parvum conserved hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Entamoeba histolytica exodeoxyribonuclease III, putative Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Cryptosporidium hominis dna-(apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania braziliensis apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania major apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma cruzi apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Wolbachia endosymbiont of Brugia malayi exonuclease III Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10771 AP endonuclease 1, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum ko:K10772 AP endonuclease 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Loa Loa (eye worm) exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Theileria parva hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Candida albicans similar to S. cerevisiae APN2 (YBL019W) DNA repair apurinic/apyrimidinic endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium knowlesi AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania infantum apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Brugia malayi exodeoxyribonuclease III family protein Get druggable targets OG5_126768 All targets in OG5_126768
Treponema pallidum exodeoxyribonuclease (exoA) Get druggable targets OG5_126768 All targets in OG5_126768
Giardia lamblia Endonuclease/Exonuclease/phosphatase Get druggable targets OG5_126768 All targets in OG5_126768
Toxoplasma gondii exonuclease III APE Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania mexicana apurinic/apyrimidinic endonuclease-redox protein,AP-endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Trichomonas vaginalis ap endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei gambiense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase Get druggable targets OG5_126768 All targets in OG5_126768
Trypanosoma congolense apurinic/apyrimidinic endonuclease, putative Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma mansoni ap endonuclease Get druggable targets OG5_126768 All targets in OG5_126768
Neospora caninum hypothetical protein Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA Get druggable targets OG5_126768 All targets in OG5_126768
Schistosoma japonicum DNA-(apurinic or apyrimidinic site) lyase 2, putative Get druggable targets OG5_126768 All targets in OG5_126768
Leishmania donovani apurinic/apyrimidinic endonuclease-redox protein Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium berghei AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative Get druggable targets OG5_126768 All targets in OG5_126768
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) Get druggable targets OG5_126768 All targets in OG5_126768
Plasmodium yoelii putative AP endonuclease-related Get druggable targets OG5_126768 All targets in OG5_126768

By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.1914 0.1567 0.1567
Echinococcus multilocularis transfer RNA-Thr 0.1903 0.1556 0.1556
Entamoeba histolytica protein kinase, putative 0.0461 0.0133 0.1289
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0408 0.0081 0.0081
Brugia malayi Immunoglobulin I-set domain containing protein 0.0483 0.0155 0.0151
Echinococcus granulosus glycogen synthase kinase 3 beta 0.1177 0.084 0.084
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0343 0.0017 0.0017
Brugia malayi cell division control protein 2 homolog 0.0407 0.008 0.0076
Giardia lamblia Kinase, AGC PKA 0.0745 0.0414 0.3804
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0343 0.0017 0.0017
Entamoeba histolytica hypothetical protein 0.1256 0.0918 1
Echinococcus multilocularis tyrosine protein kinase Src64B 0.1043 0.0708 0.0708
Entamoeba histolytica protein kinase , putative 0.0609 0.0279 0.291
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0974 0.064 0.0636
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1038 0.0703 0.0628
Brugia malayi Protein kinase domain containing protein 0.5536 0.5141 0.5139
Schistosoma mansoni protein kinase 0.2249 0.1898 0.5005
Onchocerca volvulus 0.045 0.0123 0.0147
Leishmania major protein kinase A catalytic subunit isoform 1 0.0745 0.0414 0.0337
Brugia malayi casein kinase 1, delta 0.0589 0.026 0.0255
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0589 0.026 0.026
Brugia malayi Tyrosine-protein kinase abl-1 0.1412 0.1072 0.1068
Trypanosoma cruzi casein kinase, putative 0.0589 0.026 0.0181
Giardia lamblia Kinase, CMGC CDK 0.0407 0.008 0.0604
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0682 0.0352 0.0352
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.158 0.1238 0.1238
Plasmodium falciparum protein serine/threonine kinase-1 0.1038 0.0703 0.8194
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0461 0.0133 0.0133
Trichomonas vaginalis AGC family protein kinase 0.0461 0.0133 0.1112
Echinococcus multilocularis protein kinase shaggy 0.1177 0.084 0.084
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.2204 0.1853 0.1853
Echinococcus multilocularis N chimaerin 0.033 0.0004 0.0004
Trichomonas vaginalis AGC family protein kinase 0.0503 0.0175 0.1516
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Schistosoma mansoni tyrosine kinase 0.1111 0.0775 0.2045
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0415 0.0088 0.0008
Schistosoma mansoni tyrosine kinase 0.0527 0.0199 0.0525
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.033 0.0004 0.0004
Schistosoma mansoni protein kinase C mu 0.0974 0.064 0.1688
Trichomonas vaginalis AGC family protein kinase 0.0505 0.0176 0.1528
Brugia malayi Protein kinase domain containing protein 0.4215 0.3837 0.3835
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.096 0.0626 0.0626
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0441 0.0114 0.0114
Schistosoma mansoni protein kinase 0.2249 0.1898 0.5005
Echinococcus multilocularis serine threonine protein kinase 0.0461 0.0133 0.0133
Echinococcus granulosus TGF-beta receptor type-1 0.0965 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0657 0.0326 0.0326
Entamoeba histolytica protein kinase, putative 0.0503 0.0175 0.1756
Plasmodium falciparum calcium-dependent protein kinase 5 0.0528 0.02 0.1578
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 1.046 1 1
Onchocerca volvulus 0.0494 0.0166 0.0205
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.158 0.1238 0.1234
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.1256 0.0918 0.0918
Schistosoma mansoni serine/threonine protein kinase 0.0745 0.0414 0.1093
Loa Loa (eye worm) hypothetical protein 0.0848 0.0516 0.0516
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.13 0.0961 0.0961
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.2118 0.1768 0.1768
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0653 0.0323 0.0853
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.5626 0.523 0.523
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0528 0.02 0.1578
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.1038 0.0703 0.0628
Plasmodium falciparum glycogen synthase kinase 3 0.1177 0.084 1
Trichomonas vaginalis CAMK family protein kinase 0.0528 0.02 0.1753
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.2439 0.2085 0.2085
Entamoeba histolytica protein kinase domain containing protein 0.0609 0.0279 0.291
Echinococcus granulosus tyrosine kinase 0.0872 0.0539 0.0539
Echinococcus multilocularis serine:threonine protein kinase N2 0.1613 0.127 0.127
Brugia malayi serine/threonine-protein kinase PAK 7 0.2204 0.1853 0.185
Echinococcus multilocularis serine:threonine protein kinase N2 0.1152 0.0815 0.0815
Loa Loa (eye worm) gastrulation defective protein 1 0.1745 0.1401 0.1401
Loa Loa (eye worm) TK protein kinase 0.154 0.1199 0.1199
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.1038 0.0703 0.0628
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0528 0.02 0.0121
Loa Loa (eye worm) thyroid receptor interactor 0.0809 0.0477 0.0477
Brugia malayi hypothetical protein 0.2888 0.2528 0.2525
Schistosoma mansoni serine/threonine protein kinase 0.0609 0.0279 0.0736
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0528 0.02 0.2031
Echinococcus granulosus mitogen activated protein kinase 14 1.046 1 1
Schistosoma mansoni serine/threonine protein kinase 0.0591 0.0262 0.0692
Echinococcus multilocularis death associated protein kinase 1 1.0112 0.9657 0.9657
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0408 0.0081 0.0081
Brugia malayi Hr1 repeat family protein 0.1613 0.127 0.1266
Schistosoma mansoni serine/threonine protein kinase 0.1768 0.1423 0.3754
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.1038 0.0703 0.0628
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.2439 0.2085 0.2085
Trypanosoma brucei rac serine-threonine kinase, putative 0.0503 0.0175 0.0096
Plasmodium falciparum calcium-dependent protein kinase 4 0.0528 0.02 0.1578
Echinococcus multilocularis twitchin 0.0363 0.0037 0.0037
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.1256 0.0918 0.0845
Schistosoma mansoni tyrosine kinase 0.0636 0.0306 0.0808
Schistosoma mansoni tyrosine kinase 0.039 0.0063 0.0166
Plasmodium vivax casein kinase 1, putative 0.0589 0.026 0.2772
Echinococcus multilocularis growth factor receptor bound protein 2 0.0375 0.0048 0.0048
Brugia malayi Protein kinase domain containing protein 0.1914 0.1567 0.1564
Onchocerca volvulus 0.0423 0.0096 0.011
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0415 0.0088 0.0008
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0745 0.0414 0.0337
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.1038 0.0703 0.8194
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.203 0.1681 0.1681
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0395 0.0069 0.0069
Echinococcus granulosus TGF beta receptor type 1 0.0965 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0745 0.0414 0.0414
Echinococcus multilocularis tyrosine protein kinase Src42A 0.1043 0.0708 0.0708
Brugia malayi Protein kinase domain containing protein 0.118 0.0843 0.0839
Loa Loa (eye worm) TK/ROR protein kinase 0.0441 0.0114 0.0114
Trichomonas vaginalis CK1 family protein kinase 0.0589 0.026 0.2323
Trichomonas vaginalis AGC family protein kinase 0.0609 0.0279 0.2511
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0745 0.0414 0.0337
Brugia malayi SRC-1 0.1043 0.0708 0.0704
Entamoeba histolytica protein kinase, putative 0.0503 0.0175 0.1756
Schistosoma mansoni serine/threonine protein kinase 0.0494 0.0166 0.0438
Schistosoma mansoni protein kinase 0.0609 0.0279 0.0736
Schistosoma mansoni protein kinase 0.2249 0.1898 0.5005
Echinococcus granulosus activated cdc42 kinase 1 0.1903 0.1556 0.1556
Loa Loa (eye worm) hypothetical protein 0.0638 0.0308 0.0308
Echinococcus granulosus activated cdc42 kinase 1 0.1903 0.1556 0.1556
Brugia malayi Protein kinase domain containing protein 0.045 0.0123 0.0118
Onchocerca volvulus 0.045 0.0123 0.0147
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.1737 0.1392 0.1392
Echinococcus multilocularis cyclin dependent kinase 9 0.042 0.0093 0.0093
Loa Loa (eye worm) TK/EGFR protein kinase 0.0636 0.0306 0.0306
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0415 0.0088 0.0008
Loa Loa (eye worm) hypothetical protein 0.1087 0.0751 0.0751
Loa Loa (eye worm) TK/DDR protein kinase 0.0401 0.0074 0.0074
Leishmania major casein kinase, putative 0.0589 0.026 0.0181
Plasmodium vivax serine/threonine protein kinase 6, putative 0.0609 0.0279 0.3016
Trichomonas vaginalis AGC family protein kinase 0.0461 0.0133 0.1112
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0848 0.0515 0.0515
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.118 0.0843 0.0843
Entamoeba histolytica protein kinase, putative 0.1256 0.0918 1
Entamoeba histolytica protein kinase, putative 0.1177 0.084 0.9135
Echinococcus granulosus tyrosine protein kinase Src42A 0.0641 0.0311 0.0311
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0587 0.0258 0.0258
Onchocerca volvulus 0.0848 0.0515 0.0678
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0528 0.02 0.1578
Entamoeba histolytica casein kinase, putative 0.0589 0.026 0.2692
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0671 0.0341 0.0341
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0375 0.0048 0.0048
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.1177 0.084 0.084
Entamoeba histolytica protein kinase, putative 0.0528 0.02 0.2032
Brugia malayi Fibronectin type III domain containing protein 0.0685 0.0355 0.0351
Echinococcus multilocularis tyrosine protein kinase shark 0.045 0.0123 0.0123
Echinococcus granulosus casein kinase I delta 0.0589 0.026 0.026
Echinococcus granulosus calcium dependent protein kinase 0.0359 0.0033 0.0033
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.254 0.2185 0.2185
Trichomonas vaginalis STE family protein kinase 0.1401 0.1061 1
Schistosoma mansoni tyrosine kinase 0.0636 0.0306 0.0808
Loa Loa (eye worm) SRC-1 0.1043 0.0708 0.0708
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.084 0.0508 0.0508
Trichomonas vaginalis AGC family protein kinase 0.0503 0.0175 0.1516
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.1051 0.0715 0.064
Brugia malayi Cam kinase protein 1 0.0528 0.02 0.0196
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Entamoeba histolytica protein kinase, putative 0.0386 0.0059 0.0467
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.2249 0.1898 0.1898
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0528 0.02 0.02
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2118 0.1768 0.1768
Trypanosoma brucei casein kinase I, isoform 2 0.0589 0.026 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0967 0.0632 0.1668
Loa Loa (eye worm) hypothetical protein 0.1903 0.1556 0.1556
Brugia malayi probable protein kinase 0.1573 0.1231 0.1227
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0965 0.0631 0.0631
Onchocerca volvulus 0.0671 0.0341 0.0442
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0671 0.0341 0.0899
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1038 0.0703 0.0628
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.1346 0.1007 0.1007
Loa Loa (eye worm) hypothetical protein 0.0805 0.0473 0.0473
Entamoeba histolytica cell division protein kinase 2, putative 0.0451 0.0123 0.1182
Trypanosoma cruzi aurora B kinase, putative 0.0609 0.0279 0.0201
Leishmania major protein kinase A catalytic subunit 0.0745 0.0414 0.0337
Loa Loa (eye worm) hypothetical protein 0.1087 0.0751 0.0751
Schistosoma mansoni serine/threonine protein kinase 0.344 0.3073 0.8106
Trichomonas vaginalis CK1 family protein kinase 0.0589 0.026 0.2323
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.096 0.0626 0.0626
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0407 0.008 0.008
Trichomonas vaginalis AGC family protein kinase 0.0503 0.0175 0.1516
Schistosoma mansoni tyrosine kinase 0.2316 0.1963 0.5179
Echinococcus granulosus tyrosine kinase 0.045 0.0123 0.0123
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.2888 0.2528 0.2528
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0482 0.0154 0.0154
Loa Loa (eye worm) AGC/PKN protein kinase 0.1613 0.127 0.127
Echinococcus granulosus tyrosine protein kinase Src42A 0.1043 0.0708 0.0708
Entamoeba histolytica p21-activated kinase 0.0386 0.0059 0.0467
Echinococcus granulosus cyclin dependent kinase 19 0.1914 0.1567 0.1567
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0848 0.0515 0.0515
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.1038 0.0703 0.0628
Schistosoma mansoni protein kinase 0.0343 0.0017 0.0045
Loa Loa (eye worm) hypothetical protein 0.0375 0.0048 0.0048
Echinococcus multilocularis serine:threonine protein kinase 38 0.0461 0.0133 0.0133
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0745 0.0414 0.0414
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.1043 0.0708 0.0708
Trypanosoma cruzi casein kinase, putative 0.0589 0.026 0.0181
Loa Loa (eye worm) hypothetical protein 0.0848 0.0516 0.0516
Echinococcus granulosus serine:threonine protein kinase mig 15 0.1404 0.1064 0.1064
Loa Loa (eye worm) AGC/PKA protein kinase 0.0745 0.0414 0.0414
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0653 0.0323 0.0853
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.1043 0.0707 0.0707
Schistosoma mansoni serine/threonine protein kinase 0.1914 0.1567 0.4134
Toxoplasma gondii aurora kinase 0.0609 0.0279 0.2619
Trichomonas vaginalis AGC family protein kinase 0.0609 0.0279 0.2511
Loa Loa (eye worm) CAMK protein kinase 0.0395 0.0069 0.0069
Entamoeba histolytica protein kinase, putative 0.1256 0.0918 1
Echinococcus multilocularis cyclin dependent kinase 5 0.0407 0.008 0.008
Loa Loa (eye worm) TK/ABL protein kinase 0.2519 0.2164 0.2164
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0745 0.0414 0.0337
Loa Loa (eye worm) hypothetical protein 0.0528 0.02 0.02
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1043 0.0708 0.0708
Trichomonas vaginalis AGC family protein kinase 0.0503 0.0175 0.1516
Entamoeba histolytica protein kinase domain containing protein 0.0415 0.0088 0.0794
Loa Loa (eye worm) hypothetical protein 0.0653 0.0323 0.0323
Leishmania major protein kinase A catalytic subunit isoform 2 0.0745 0.0414 0.0337
Trichomonas vaginalis AGC family protein kinase 0.0503 0.0175 0.1516
Trichomonas vaginalis AGC family protein kinase 0.0503 0.0175 0.1516
Echinococcus granulosus protein kinase 0.0902 0.0568 0.0568
Schistosoma mansoni tyrosine kinase 0.0621 0.0291 0.0768
Schistosoma mansoni protein kinase 0.1573 0.1231 0.3246
Loa Loa (eye worm) hypothetical protein 0.0671 0.0341 0.0341
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 1.046 1 1
Trichomonas vaginalis CMGC family protein kinase 0.0407 0.008 0.0604
Plasmodium falciparum protein kinase, putative 0.0415 0.0088 0.0111
Brugia malayi Immunoglobulin I-set domain containing protein 0.0685 0.0355 0.0351
Loa Loa (eye worm) AGC/AKT protein kinase 0.0503 0.0175 0.0175
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0745 0.0414 0.0414
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0636 0.0306 0.0306
Schistosoma mansoni tyrosine kinase 0.0621 0.0291 0.0768
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0671 0.0341 0.0899
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0589 0.026 0.026
Schistosoma mansoni nephrin 0.088 0.0547 0.1442
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0671 0.0341 0.0263
Entamoeba histolytica protein kinase domain containing protein 0.1177 0.084 0.9135
Schistosoma mansoni titin 0.0395 0.0069 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0373 0.0047 0.0123
Schistosoma mansoni tyrosine kinase 0.4168 0.3791 1
Loa Loa (eye worm) TK protein kinase 0.0668 0.0338 0.0338
Trichomonas vaginalis AGC family protein kinase 0.0609 0.0279 0.2511
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.2439 0.2085 0.2085
Schistosoma mansoni tyrosine kinase 0.045 0.0123 0.0323
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.1737 0.1392 0.1389
Plasmodium vivax serine/threonine kinase-1, putative 0.1038 0.0703 0.8291
Echinococcus granulosus aurora kinase A 0.0609 0.0279 0.0279
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0461 0.0133 0.0133
Brugia malayi Protein kinase domain 0.0343 0.0017 0.0013
Giardia lamblia Kinase, CMGC GSK 0.1177 0.084 0.7883
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.008 0.0211
Giardia lamblia Kinase, CAMK CAMKL 0.0363 0.0037 0.0191
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.045 0.0123 0.0123
Echinococcus multilocularis Immunoglobulin 0.0653 0.0323 0.0323
Echinococcus multilocularis cyclin dependent kinase 1 0.0407 0.008 0.008
Schistosoma mansoni tyrosine kinase 0.1043 0.0708 0.1866
Echinococcus multilocularis protein kinase c iota type 0.0587 0.0258 0.0258
Echinococcus multilocularis neuroglian 0.0848 0.0515 0.0515
Trichomonas vaginalis STE family protein kinase 0.1401 0.1061 1
Brugia malayi Protein kinase domain containing protein 0.7837 0.7412 0.7411
Loa Loa (eye worm) hypothetical protein 0.0679 0.0349 0.0349
Schistosoma mansoni protein kinase 0.1401 0.1061 0.2799
Echinococcus multilocularis activated cdc42 kinase 1 0.1903 0.1556 0.1556
Schistosoma mansoni serine/threonine protein kinase 0.0461 0.0133 0.0351
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0641 0.0311 0.0311
Entamoeba histolytica protein kinase, putative 0.0609 0.0279 0.291
Leishmania major protein kinase, putative 0.0528 0.02 0.0121
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.0609 0.0279 0.291
Echinococcus granulosus insulin receptor 0.1111 0.0775 0.0775
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.172 0.1376 0.1373
Echinococcus multilocularis titin 0.0395 0.0069 0.0069
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0745 0.0414 0.4396
Entamoeba histolytica protein kinase, putative 0.0528 0.02 0.2032
Echinococcus granulosus cyclin dependent kinase 1 0.0407 0.008 0.008
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0745 0.0414 0.041
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.2118 0.1768 0.1768
Plasmodium falciparum casein kinase 1 0.0589 0.026 0.2362
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.1043 0.0708 0.0708
Brugia malayi intracellular kinase 0.1177 0.084 0.0836
Trichomonas vaginalis AGC family protein kinase 0.0503 0.0175 0.1516
Echinococcus multilocularis aurora kinase A 0.0609 0.0279 0.0279
Trichomonas vaginalis CMGC family protein kinase 0.1177 0.084 0.7883
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0589 0.026 0.0181
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0745 0.0414 0.0337
Brugia malayi p70 ribosomal S6 kinase beta 0.0461 0.0133 0.0129
Brugia malayi Serine/threonine-protein kinase SULU 0.2888 0.2528 0.2525
Loa Loa (eye worm) hypothetical protein 0.0869 0.0536 0.0536
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0415 0.0088 0.0088
Schistosoma mansoni protein kinase 0.0902 0.0568 0.1499
Schistosoma mansoni serine/threonine protein kinase 0.1737 0.1392 0.3672
Echinococcus multilocularis casein kinase I alpha 0.0589 0.026 0.026
Brugia malayi Immunoglobulin I-set domain containing protein 0.0395 0.0069 0.0065
Echinococcus multilocularis casein kinase I alpha 0.0589 0.026 0.026
Loa Loa (eye worm) CMGC/CLK protein kinase 0.1038 0.0703 0.0703
Echinococcus granulosus protein tyrosine kinase 0.4168 0.3791 0.3791
Onchocerca volvulus 0.7837 0.7412 1
Leishmania major protein kinase, putative 0.1038 0.0703 0.0628
Echinococcus granulosus fibroblast growth factor receptor 4 0.1346 0.1007 0.1007
Echinococcus multilocularis tyrosine protein kinase Fgr 0.1043 0.0708 0.0708
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.1401 0.1061 0.0989
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0848 0.0515 0.0515
Trichomonas vaginalis CMGC family protein kinase 0.0407 0.008 0.0604
Echinococcus granulosus serine:threonine protein kinase TAO1 0.2888 0.2528 0.2528
Toxoplasma gondii casein kinase I 0.0589 0.026 0.2362
Schistosoma mansoni serine/threonine protein kinase 0.0745 0.0414 0.1093
Echinococcus granulosus activin receptor type 0.4482 0.4101 0.4101
Entamoeba histolytica protein kinase domain containing protein 0.1256 0.0918 1
Loa Loa (eye worm) hypothetical protein 0.0898 0.0564 0.0564
Brugia malayi serine/threonine kinase 12 0.0609 0.0279 0.0275
Brugia malayi Protein kinase domain containing protein 0.0461 0.0133 0.0129
Echinococcus multilocularis mitogen activated protein kinase 14 1.046 1 1
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0483 0.0155 0.0155
Schistosoma mansoni growth factor receptor-bound protein 0.0375 0.0048 0.0127
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0745 0.0414 0.0414
Echinococcus granulosus MAM 0.0376 0.005 0.005
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0528 0.02 0.1578
Echinococcus granulosus defective proboscis extension response 0.0653 0.0323 0.0323
Loa Loa (eye worm) hypothetical protein 0.0679 0.0349 0.0349
Loa Loa (eye worm) hypothetical protein 0.0934 0.0601 0.0601
Trypanosoma cruzi casein kinase, putative 0.0589 0.026 0.0181
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0587 0.0258 0.0258
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.042 0.0093 0.0093
Schistosoma mansoni rap gtpase-activating protein 0.0671 0.0341 0.0899
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.033 0.0004 0.0004
Brugia malayi Protein kinase domain containing protein 0.0423 0.0096 0.0091
Schistosoma mansoni hypothetical protein 0.0376 0.005 0.0131
Schistosoma mansoni tyrosine kinase 0.2385 0.2032 0.5359
Brugia malayi bone morphogenetic protein type 1 receptor 0.1043 0.0707 0.0704
Trichomonas vaginalis STE family protein kinase 0.1401 0.1061 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0415 0.0088 0.0111
Schistosoma mansoni serine/threonine protein kinase 0.1038 0.0703 0.1854
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.2249 0.1898 0.1898
Loa Loa (eye worm) hypothetical protein 0.0771 0.0439 0.0439
Brugia malayi serine/threonine-protein kinase 6 0.0609 0.0279 0.0275
Trypanosoma brucei protein kinase, putative 0.0415 0.0088 0.0008
Echinococcus granulosus casein kinase I delta 0.0589 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.1656 0.1313 0.1313
Loa Loa (eye worm) AUR protein kinase 0.0609 0.0279 0.0279
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.203 0.1681 0.1681
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0343 0.0017 0.0017
Echinococcus multilocularis c Jun NH2 terminal kinase 0.344 0.3073 0.3073
Onchocerca volvulus 0.0376 0.005 0.0048
Brugia malayi Furin-like cysteine rich region family protein 0.0636 0.0306 0.0302
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.344 0.3073 0.3073
Brugia malayi Protein kinase domain containing protein 0.0407 0.008 0.0076
Echinococcus multilocularis roundabout 2 0.0966 0.0632 0.0632
Loa Loa (eye worm) AUR protein kinase 0.0609 0.0279 0.0279
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.1043 0.0708 0.0708
Trypanosoma cruzi casein kinase, putative 0.0589 0.026 0.0181
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.1346 0.1007 0.1007
Brugia malayi Immunoglobulin I-set domain containing protein 0.3488 0.312 0.3117
Echinococcus multilocularis raf serine:threonine protein kinase 0.0373 0.0047 0.0047
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0375 0.0048 0.0048
Echinococcus multilocularis epidermal growth factor receptor 0.0636 0.0306 0.0306
Brugia malayi Tyrosine-protein kinase abl-1 0.1278 0.094 0.0936
Schistosoma mansoni protein kinase 0.1043 0.0707 0.1866
Plasmodium vivax glycogen synthase kinase 3, putative 0.1177 0.084 1
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.096 0.0626 0.0626
Schistosoma mansoni vav2 0.0373 0.0046 0.0122
Echinococcus multilocularis epidermal growth factor receptor 0.0636 0.0306 0.0306
Brugia malayi Protein kinase domain containing protein 0.2439 0.2085 0.2082
Schistosoma mansoni vesicular amine transporter 0.0653 0.0323 0.0853
Echinococcus granulosus raf serine:threonine protein kinase 0.0373 0.0047 0.0047
Entamoeba histolytica casein kinase 1, putative 0.0589 0.026 0.2692
Loa Loa (eye worm) hypothetical protein 0.0376 0.005 0.005
Loa Loa (eye worm) CAMK/PIM protein kinase 0.2118 0.1768 0.1768
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0528 0.02 0.02
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0967 0.0632 0.0632
Entamoeba histolytica protein kinase, putative 0.0668 0.0338 0.3563
Echinococcus multilocularis protein KINase family member (kin 25) 0.0884 0.0551 0.0551
Echinococcus granulosus cyclin dependent kinase 9 0.042 0.0093 0.0093
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0441 0.0114 0.0114
Schistosoma mansoni kinase 0.042 0.0093 0.0244
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0745 0.0414 0.4396
Schistosoma mansoni serine/threonine protein kinase 0.0408 0.0081 0.0214
Brugia malayi Protein kinase domain containing protein 0.1903 0.1556 0.1553
Schistosoma mansoni tyrosine kinase 0.0636 0.0306 0.0808
Brugia malayi Temporarily assigned gene name protein 59 0.0671 0.0341 0.0337
Echinococcus granulosus mitogen activated protein kinase 11 1.046 1 1
Onchocerca volvulus 0.0805 0.0473 0.0621
Plasmodium falciparum serine/threonine protein kinase, putative 0.0609 0.0279 0.2619
Schistosoma mansoni serine/threonine kinase 0.0461 0.0133 0.0351
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.033 0.0004 0.0011
Brugia malayi Stress-activated protein kinase jnk-1 0.344 0.3073 0.307
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.1177 0.084 0.0766
Leishmania major protein kinase, putative 0.0415 0.0088 0.0008
Echinococcus multilocularis casein kinase i 0.0589 0.026 0.026
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0745 0.0414 0.0414
Loa Loa (eye worm) AGC/NDR protein kinase 0.0461 0.0133 0.0133
Schistosoma mansoni protein kinase 0.0415 0.0088 0.0233
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1256 0.0918 0.0845
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 1.046 1 1
Brugia malayi C1-like domain containing protein 0.0974 0.064 0.0636
Brugia malayi cyclin-dependent kinase 7 homolog 0.0726 0.0395 0.0391
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0408 0.0081 0.0081
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.1401 0.1061 0.1057
Loa Loa (eye worm) hypothetical protein 0.0771 0.0439 0.0439
Trypanosoma cruzi casein kinase, delta isoform, putative 0.042 0.0093 0.0013
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0407 0.008 0.008
Echinococcus multilocularis Immunoglobulin 0.0653 0.0323 0.0323
Brugia malayi Protein kinase domain containing protein 0.2118 0.1768 0.1765
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.1256 0.0918 0.0845
Echinococcus granulosus roundabout 2 0.0966 0.0632 0.0632
Echinococcus granulosus cyclin dependent kinase 7 0.0682 0.0352 0.0352
Schistosoma mansoni serine/threonine protein kinase 0.042 0.0093 0.0244
Schistosoma mansoni tyrosine kinase 0.1043 0.0708 0.1866
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.074 0.0409 0.0409
Echinococcus granulosus serine:threonine protein kinase N2 0.1152 0.0815 0.0815
Echinococcus granulosus twitchin 0.1017 0.0682 0.0682
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0372 0.0046 0.0323
Brugia malayi Protein kinase domain containing protein 0.1111 0.0775 0.0771
Echinococcus granulosus rho-associated protein kinase 1 0.0494 0.0166 0.0166
Echinococcus granulosus serine:threonine protein kinase 12 B 0.0609 0.0279 0.0279
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 1.046 1 1
Brugia malayi Protein kinase domain containing protein 0.045 0.0123 0.0118
Echinococcus granulosus cyclin dependent kinase 5 0.0407 0.008 0.008
Echinococcus granulosus N chimaerin 0.033 0.0004 0.0004
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0745 0.0414 0.0337
Loa Loa (eye worm) AGC/PKA protein kinase 0.0745 0.0414 0.0414
Giardia lamblia Kinase, CMGC GSK 0.1177 0.084 0.7883
Echinococcus granulosus tyrosine protein kinase Srms 0.045 0.0123 0.0123
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1177 0.084 0.084
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0461 0.0133 0.0133
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0528 0.02 0.02
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.1401 0.1061 0.0989
Brugia malayi protein kinase C II. 0.0587 0.0258 0.0254
Schistosoma mansoni nck2/grb4 0.0375 0.0048 0.0127
Schistosoma mansoni growth factor receptor-bound protein 0.039 0.0064 0.0169
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0902 0.0568 0.0568
Brugia malayi Fes/CIP4 homology domain containing protein 0.0809 0.0477 0.0473
Echinococcus granulosus protein kinase C gamma type 0.0461 0.0133 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0967 0.0632 0.1668
Schistosoma mansoni serine/threonine protein kinase 0.0682 0.0352 0.0928
Schistosoma mansoni atypical protein kinase C 0.0587 0.0258 0.068
Schistosoma mansoni serine/threonine protein kinase 0.2888 0.2528 0.6668
Loa Loa (eye worm) RhoGAP domain-containing protein 0.033 0.0004 0.0004
Echinococcus multilocularis 0.0869 0.0536 0.0536
Brugia malayi Protein kinase domain containing protein 0.0503 0.0175 0.0171
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.1177 0.084 1
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.084 0.0508 0.0508
Echinococcus granulosus casein kinase I alpha 0.0589 0.026 0.026
Echinococcus multilocularis activin receptor type 0.4482 0.4101 0.4101
Loa Loa (eye worm) hypothetical protein 0.0475 0.0148 0.0148
Schistosoma mansoni tyrosine kinase 0.0884 0.0551 0.1453
Loa Loa (eye worm) TK/INSR protein kinase 0.1111 0.0775 0.0775
Loa Loa (eye worm) hypothetical protein 0.0848 0.0516 0.0516
Echinococcus multilocularis dual specificity mitogen activated protein 0.1401 0.1061 0.1061
Plasmodium falciparum calcium-dependent protein kinase 2 0.0528 0.02 0.1578
Schistosoma mansoni cell adhesion molecule 0.0772 0.044 0.1161
Trichomonas vaginalis CMGC family protein kinase 0.1038 0.0703 0.6568
Onchocerca volvulus 0.0589 0.026 0.0332
Echinococcus granulosus tyrosine protein kinase HCK 0.0668 0.0338 0.0338
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0653 0.0323 0.0323
Echinococcus granulosus dual specificity mitogen activated protein 0.1401 0.1061 0.1061
Echinococcus multilocularis insulin receptor 0.1111 0.0775 0.0775
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0967 0.0632 0.0632
Echinococcus multilocularis tyrosine kinase 0.045 0.0123 0.0123
Echinococcus granulosus tyrosine protein kinase Lyn 0.1212 0.0874 0.0874
Schistosoma mansoni tyrosine kinase 0.039 0.0063 0.0166
Giardia lamblia Kinase, CMGC CDK 0.0407 0.008 0.0604
Loa Loa (eye worm) hypothetical protein 0.4912 0.4525 0.4525
Schistosoma mansoni hypothetical protein 0.0376 0.005 0.0131
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0528 0.02 0.02
Schistosoma mansoni serine/threonine protein kinase 0.13 0.0961 0.2535
Schistosoma mansoni serine/threonine protein kinase 0.0407 0.008 0.0211
Loa Loa (eye worm) TK/KIN16 protein kinase 0.3488 0.312 0.312
Loa Loa (eye worm) hypothetical protein 0.0685 0.0355 0.0355
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0577 0.0248 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.1038 0.0703 0.1854
Trypanosoma brucei mitogen-activated protein kinase 3, putative 1.046 1 1
Echinococcus granulosus tyrosine protein kinase shark 0.045 0.0123 0.0123
Leishmania major protein kinase, putative 0.1038 0.0703 0.0628
Entamoeba histolytica PH domain containing protein kinase, putative 0.0788 0.0456 0.4876
Brugia malayi Protein kinase domain containing protein 0.045 0.0123 0.0118
Loa Loa (eye worm) hypothetical protein 0.0685 0.0355 0.0355
Echinococcus multilocularis mitogen activated protein kinase 14 1.046 1 1
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0528 0.02 0.2031
Entamoeba histolytica protein kinase, putative 0.0461 0.0133 0.1289
Schistosoma mansoni protein kinase 0.0965 0.0631 0.1664
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0407 0.008 0.008
Entamoeba histolytica protein kinase, putative 0.0386 0.0059 0.0467
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.0609 0.0279 0.0279
Brugia malayi protein unc-22 0.0395 0.0069 0.0065
Echinococcus granulosus insulin growth factor 1 receptor beta 0.1143 0.0807 0.0807
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0621 0.0291 0.0768
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0577 0.0248 0.0248
Entamoeba histolytica cell division protein kinase 2, putative 0.0407 0.008 0.07
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.1177 0.084 0.0766
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.096 0.0626 0.0622
Brugia malayi hypothetical protein 0.0685 0.0355 0.0351
Loa Loa (eye worm) hypothetical protein 0.0884 0.0551 0.0551
Brugia malayi Protein kinase domain containing protein 0.1256 0.0918 0.0914
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0343 0.0017 0.0017
Loa Loa (eye worm) CMGC/GSK protein kinase 0.1177 0.084 0.084
Echinococcus granulosus serine:threonine protein kinase N2 0.1613 0.127 0.127
Echinococcus multilocularis cyclin dependent kinase 1 0.0407 0.008 0.008
Loa Loa (eye worm) hypothetical protein 0.1038 0.0702 0.0702
Echinococcus multilocularis dual specificity protein kinase clk2 0.1038 0.0703 0.0703
Brugia malayi Protein kinase domain containing protein 0.045 0.0123 0.0118
Echinococcus multilocularis tyrosine protein kinase Srms 0.0872 0.0539 0.0539
Echinococcus multilocularis MAM 0.0376 0.005 0.005
Echinococcus multilocularis tyrosine protein kinase HCK 0.0668 0.0338 0.0338
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0872 0.0539 0.0539
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.13 0.0961 0.0961
Loa Loa (eye worm) hypothetical protein 0.0376 0.005 0.005
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.1256 0.0918 0.0845
Echinococcus granulosus dual specificity protein kinase clk2 0.1038 0.0703 0.0703
Echinococcus granulosus titin 0.0395 0.0069 0.0069
Trichomonas vaginalis AGC family protein kinase 0.0609 0.0279 0.2511
Echinococcus granulosus c-Jun N-terminal kinases 0.344 0.3073 0.3073
Loa Loa (eye worm) IKK protein kinase 0.7837 0.7412 0.7412
Echinococcus granulosus Protein kinase C brain isozyme 0.0587 0.0258 0.0258
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0528 0.02 0.2031
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0589 0.026 0.026
Loa Loa (eye worm) hypothetical protein 0.1404 0.1064 0.1064
Trypanosoma cruzi casein kinase, putative 0.0589 0.026 0.0181
Brugia malayi Protein kinase domain containing protein 0.0461 0.0133 0.0129
Echinococcus multilocularis fibroblast growth factor receptor 4 0.1346 0.1007 0.1007
Echinococcus granulosus epidermal growth factor receptor 0.0636 0.0306 0.0306
Loa Loa (eye worm) inward rectifying k channel family protein 1 0.0848 0.0516 0.0516
Brugia malayi hypothetical protein 0.0671 0.0341 0.0337
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0872 0.0539 0.0539
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0461 0.0133 0.0133
Giardia lamblia Kinase, CMGC CLK 0.1038 0.0703 0.6568
Echinococcus granulosus NDR protein kinase 0.0461 0.0133 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.2118 0.1768 0.4664
Plasmodium falciparum calcium-dependent protein kinase 1 0.0528 0.02 0.1578
Loa Loa (eye worm) hypothetical protein 0.0771 0.0439 0.0439
Brugia malayi protein C17H12.11 0.0679 0.0349 0.0345
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1043 0.0708 0.0708
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.2888 0.2528 0.2528
Echinococcus granulosus tyrosine protein kinase Blk 0.0872 0.0539 0.0539
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0375 0.0048 0.0127
Brugia malayi Immunoglobulin I-set domain containing protein 0.154 0.1199 0.1195
Brugia malayi Serine/threonine-protein kinase Pim-3 0.2118 0.1768 0.1765
Echinococcus multilocularis cyclin dependent kinase 19 0.1914 0.1567 0.1567
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0415 0.0088 0.0088
Echinococcus multilocularis NCK adaptor protein 0.039 0.0064 0.0064
Echinococcus multilocularis tyrosine protein kinase ABL1 0.2519 0.2164 0.2164
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.158 0.1238 0.1238
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0343 0.0017 0.0017
Echinococcus granulosus c src tyrosine kinase 0.0621 0.0291 0.0291
Entamoeba histolytica PH domain containing protein kinase, putative 0.0788 0.0456 0.4876
Trichomonas vaginalis CMGC family protein kinase 0.0407 0.008 0.0604
Schistosoma mansoni protein kinase 0.2439 0.2085 0.5501
Brugia malayi Protein kinase domain containing protein 0.0848 0.0515 0.0511
Echinococcus multilocularis 0.0902 0.0568 0.0568
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.0258 0.068
Echinococcus granulosus NCK adaptor protein 0.0375 0.0048 0.0048
Onchocerca volvulus 0.0408 0.0081 0.0091
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.1401 0.1061 0.0989
Schistosoma mansoni serine/threonine protein kinase 0.0363 0.0037 0.0098
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0461 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0401 0.0074 0.0074
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0343 0.0017 0.0017
Echinococcus granulosus tyrosine protein kinase Fyn 0.1043 0.0708 0.0708
Giardia lamblia Aurora kinase 0.0609 0.0279 0.2511
Schistosoma mansoni serine/threonine protein kinase 0.0589 0.026 0.0685
Echinococcus granulosus Vam6:Vps39 protein 0.0671 0.0341 0.0341
Loa Loa (eye worm) hypothetical protein 0.0934 0.0601 0.0601
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0884 0.0551 0.0551
Onchocerca volvulus 0.0395 0.0069 0.0074
Schistosoma mansoni serine/threonine protein kinase 0.0745 0.0414 0.1093
Loa Loa (eye worm) TK protein kinase 0.0872 0.0539 0.0539
Schistosoma mansoni protein kinase 0.0343 0.0017 0.0045
Brugia malayi Variant SH3 domain containing protein 0.0375 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.045 0.0123 0.0123
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0528 0.02 0.02
Plasmodium vivax calcium-dependent protein kinase, putative 0.0528 0.02 0.2031
Echinococcus multilocularis casein kinase I delta 0.0589 0.026 0.026
Onchocerca volvulus Tyrosine kinase homolog 0.2943 0.2582 0.3471
Schistosoma mansoni tyrosine kinase 0.042 0.0093 0.0246
Loa Loa (eye worm) hypothetical protein 0.074 0.0409 0.0409
Trichomonas vaginalis CMGC family protein kinase 0.1177 0.084 0.7883
Schistosoma mansoni protein kinase 0.0415 0.0088 0.0233
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.0609 0.0279 0.291
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0461 0.0133 0.0133
Schistosoma mansoni serine/threonine protein kinase 0.0682 0.0352 0.0928
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0495 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0679 0.0349 0.0349
Entamoeba histolytica protein kinase, putative 0.0609 0.0279 0.291
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Loa Loa (eye worm) TK/FAK protein kinase 0.4215 0.3837 0.3837
Toxoplasma gondii AGC kinase 0.0745 0.0414 0.4396
Brugia malayi hypothetical protein 0.0679 0.0349 0.0345
Brugia malayi Protein kinase domain containing protein 0.1038 0.0703 0.0699
Echinococcus granulosus hypothetical protein 0.0869 0.0536 0.0536
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.13 0.0961 0.0961
Schistosoma mansoni serine/threonine protein kinase 0.096 0.0626 0.1652
Echinococcus multilocularis mitogen activated protein kinase 11 1.046 1 1
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.172 0.1376 0.1376
Echinococcus multilocularis casein kinase I alpha 0.0589 0.026 0.026
Giardia lamblia Kinase, STE STE20 0.1401 0.1061 1
Brugia malayi cyclin-dependent kinase 9 0.042 0.0093 0.0089
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Echinococcus granulosus tyrosine protein kinase Btk29A 0.254 0.2185 0.2185
Echinococcus multilocularis PAK box P21 Rho binding 0.0343 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0685 0.0355 0.0355
Schistosoma mansoni hypothetical protein 0.0671 0.0341 0.0899
Onchocerca volvulus 0.045 0.0123 0.0147
Echinococcus multilocularis serine:threonine protein kinase N2 0.0461 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0671 0.0341 0.0341
Trypanosoma brucei aurora B kinase 0.0609 0.0279 0.0201
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.2118 0.1768 0.2371
Onchocerca volvulus 0.045 0.0123 0.0147
Schistosoma mansoni tyrosine kinase 0.039 0.0063 0.0166
Giardia lamblia Kinase, CAMK CAMKL 0.0363 0.0037 0.0191
Loa Loa (eye worm) hypothetical protein 0.0638 0.0308 0.0308
Echinococcus granulosus Immunoglobulin 0.0653 0.0323 0.0323
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0495 0.0167 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.1256 0.0918 0.2421
Echinococcus granulosus tyrosine protein kinase Fyn 0.1043 0.0708 0.0708
Trichomonas vaginalis AGC family protein kinase 0.0503 0.0175 0.1516
Leishmania major protein kinase, putative 0.0609 0.0279 0.0201
Loa Loa (eye worm) hypothetical protein 0.0653 0.0323 0.0323
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0528 0.02 0.02
Brugia malayi protein-tyrosine kinase 0.0872 0.0539 0.0535
Echinococcus granulosus tyrosine protein kinase Src64B 0.1043 0.0708 0.0708
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.0609 0.0279 0.291
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0745 0.0414 0.0414
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.1143 0.0807 0.0807
Onchocerca volvulus 0.1177 0.084 0.1117
Echinococcus multilocularis rho associated protein kinase 0.0494 0.0166 0.0166
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.1177 0.084 0.2216
Echinococcus granulosus dual specificity 0.1256 0.0918 0.0918
Brugia malayi Variant SH3 domain containing protein 0.0375 0.0048 0.0044
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.033 0.0004 0.0011
Echinococcus granulosus casein kinase i 0.0589 0.026 0.026
Echinococcus multilocularis dual specificity 0.1256 0.0918 0.0918
Giardia lamblia Kinase, AGC AKT 0.1008 0.0673 0.6285
Echinococcus granulosus casein kinase I alpha 0.0589 0.026 0.026
Entamoeba histolytica protein kinase, putative 0.0372 0.0046 0.0323
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0745 0.0414 0.0337
Giardia lamblia Kinase, CK1 Casein kinase 0.0589 0.026 0.2323
Trypanosoma brucei protein kinase, putative 0.1177 0.084 0.0766
Echinococcus multilocularis cyclin dependent kinase 0.0407 0.008 0.008
Schistosoma mansoni tyrosine kinase 0.1346 0.1007 0.2655
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0528 0.02 0.0196
Onchocerca volvulus 0.2502 0.2147 0.2883
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0528 0.02 0.02
Brugia malayi Protein kinase domain containing protein 0.0495 0.0167 0.0163
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0745 0.0414 0.4698
Schistosoma mansoni serine/threonine protein kinase 0.1613 0.127 0.3349
Echinococcus granulosus neuroglian 0.0848 0.0515 0.0515
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.0258 0.068
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.1043 0.0708 0.0708
Brugia malayi Protein kinase domain containing protein 0.045 0.0123 0.0118
Echinococcus multilocularis calcium dependent protein kinase 0.0359 0.0033 0.0033
Entamoeba histolytica SH2-protein kinase domain containing protein 0.045 0.0123 0.1172
Entamoeba histolytica protein kinase domain containing protein 0.1177 0.084 0.9135
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0671 0.0341 0.0263
Echinococcus granulosus titin 0.0395 0.0069 0.0069
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.1401 0.1061 0.1061
Echinococcus granulosus protein kinase c iota type 0.0587 0.0258 0.0258
Schistosoma mansoni adapter molecule crk 0.0375 0.0048 0.0127
Brugia malayi casein kinase I 0.0589 0.026 0.0255
Schistosoma mansoni serine/threonine protein kinase 0.0528 0.02 0.0528
Onchocerca volvulus 0.0771 0.0439 0.0575
Loa Loa (eye worm) hypothetical protein 0.0848 0.0515 0.0515
Loa Loa (eye worm) hypothetical protein 0.1232 0.0894 0.0894
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.1043 0.0708 0.0708
Brugia malayi ribosomal protein S6 kinase alpha 3 0.1008 0.0673 0.0669
Onchocerca volvulus 0.042 0.0093 0.0106
Echinococcus multilocularis cyclin dependent kinase 9 0.0464 0.0136 0.0136
Entamoeba histolytica protein kinase domain containing protein 0.042 0.0093 0.084
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0407 0.008 0.008
Schistosoma mansoni protein kinase 0.0415 0.0088 0.0233
Echinococcus granulosus casein kinase I alpha 0.0589 0.026 0.026
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0671 0.0341 0.0263
Trichomonas vaginalis AGC family protein kinase 0.0745 0.0414 0.3804
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.158 0.1238 0.1238
Echinococcus granulosus tyrosine protein kinase ABL1 0.2519 0.2164 0.2164
Echinococcus multilocularis protein tyrosine kinase 0.4168 0.3791 0.3791
Echinococcus granulosus cyclin dependent kinase 0.0407 0.008 0.008
Echinococcus granulosus epidermal growth factor receptor 0.0636 0.0306 0.0306
Echinococcus multilocularis tyrosine protein kinase Abl 0.1412 0.1072 0.1072
Echinococcus multilocularis mitogen activated protein kinase 11 1.046 1 1
Trichomonas vaginalis CK1 family protein kinase 0.0589 0.026 0.2323
Schistosoma mansoni protein kinase 0.0343 0.0017 0.0045
Loa Loa (eye worm) AUR protein kinase 0.0609 0.0279 0.0279
Echinococcus granulosus tyrosine protein kinase Fps85D 0.045 0.0123 0.0123
Echinococcus granulosus protein kinase shaggy 0.1177 0.084 0.084
Toxoplasma gondii AGC kinase 0.0461 0.0133 0.0698
Brugia malayi SH2 domain containing protein 0.045 0.0123 0.0118
Echinococcus multilocularis tyrosine protein kinase Fyn 0.1043 0.0708 0.0708
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0408 0.0081 0.0081
Echinococcus granulosus tyrosine protein kinase Fyn 0.1043 0.0708 0.0708
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Plasmodium vivax protein kinase Crk2 0.0407 0.008 0.0538
Echinococcus granulosus cyclin dependent kinase 9 0.0464 0.0136 0.0136
Loa Loa (eye worm) TK/ALK protein kinase 0.5534 0.5139 0.5139
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0745 0.0414 0.0337
Loa Loa (eye worm) hypothetical protein 0.0376 0.005 0.005
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0974 0.064 0.064
Schistosoma mansoni tyrosine kinase 0.1111 0.0775 0.2045
Brugia malayi hypothetical protein 0.0376 0.005 0.0046
Brugia malayi Sex muscle abnormal protein 5 0.0375 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0671 0.0341 0.0341
Schistosoma mansoni serine/threonine protein kinase 0.0395 0.0069 0.0181
Schistosoma mansoni serine/threonine protein kinase 0.0461 0.0133 0.0351
Onchocerca volvulus 0.045 0.0123 0.0147
Echinococcus multilocularis tyrosine protein kinase Blk 0.0872 0.0539 0.0539
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0745 0.0414 0.0414
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0495 0.0167 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0587 0.0258 0.068
Echinococcus multilocularis TGF beta receptor type 1 0.0965 0.0631 0.0631
Brugia malayi hypothetical protein 0.045 0.0123 0.0118
Brugia malayi Protein kinase domain containing protein 0.0722 0.0391 0.0387
Echinococcus multilocularis c src tyrosine kinase 0.0621 0.0291 0.0291
Onchocerca volvulus 0.045 0.0123 0.0147
Toxoplasma gondii hypothetical protein 0.0848 0.0516 0.5732
Onchocerca volvulus 0.0679 0.0349 0.0452
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0745 0.0414 0.0414
Loa Loa (eye worm) TK/FER protein kinase 0.045 0.0123 0.0123
Schistosoma mansoni vam6/vps39 related 0.0671 0.0341 0.0899
Brugia malayi SH2 domain containing protein 0.045 0.0123 0.0118
Echinococcus granulosus growth factor receptor bound protein 2 0.039 0.0064 0.0064
Echinococcus granulosus protein kinase c epsilon type 0.0587 0.0258 0.0258
Plasmodium falciparum calcium-dependent protein kinase 3 0.0528 0.02 0.1578
Toxoplasma gondii AGC kinase 0.0745 0.0414 0.4396
Echinococcus multilocularis casein kinase I delta 0.0589 0.026 0.026
Brugia malayi serine/threonine protein kinase 6 0.0609 0.0279 0.0275
Echinococcus multilocularis protein kinase c epsilon type 0.0587 0.0258 0.0258
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0528 0.02 0.02
Echinococcus multilocularis cyclin dependent kinase 7 0.0682 0.0352 0.0352
Schistosoma mansoni protein kinase 0.0589 0.026 0.0685
Schistosoma mansoni serine/threonine protein kinase 0.0408 0.0081 0.0214
Echinococcus multilocularis G protein coupled receptor kinase 6 0.158 0.1238 0.1238
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0671 0.0341 0.0341
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0461 0.0133 0.0133

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 0.9466 uM PubChem BioAssay. qHTS Assay for Inhibitors of the Human Apurinic/apyrimidinic Endonuclease 1 (APE1). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 100 um PUBCHEM_BIOASSAY: qHTS Inhibitors of AmpC Beta-Lactamase (assay with detergent). (Class of assay: confirmatory) [Related pubchem assays: 1002 (Confirmation Concentration-Response Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent)), 585 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay without detergent) - a screen old NIH MLSMR collection), 584 (Promiscuous and Specific Inhibitors of AmpC Beta-Lactamase (assay with detergent) - a screen of the old NIH MLSMR collection), 1003 (Confirmation Cuvette-Based Assay for Inhibitors of AmpC Beta-Lactamase (assay with detergent))] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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