Detailed information for compound 1399901

Basic information

Technical information
  • TDR Targets ID: 1399901
  • Name: SMR000060615
  • MW: 280.344 | Formula: C16H12N2OS
  • H donors: 0 H acceptors: 1 LogP: 2.81 Rotable bonds: 0
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=c1nc2c3ccccc3Cn2c2c1c1CCCc1s2
  • InChi: 1S/C16H12N2OS/c19-15-13-11-6-3-7-12(11)20-16(13)18-8-9-4-1-2-5-10(9)14(18)17-15/h1-2,4-5H,3,6-8H2
  • InChiKey: WBHQNKPWADBVMH-UHFFFAOYSA-N  

Network

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Synonyms

  • T0504-2553
  • MLS000097971
  • Oprea1_127618
  • ZINC03195226

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Entamoeba histolytica casein kinase, putative 0.0281 0.0295 0.2101
Plasmodium falciparum glycogen synthase kinase 3 0.0592 0.1008 0.86
Schistosoma mansoni protein kinase 0.0788 0.1456 0.3951
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0876 0.1658 0.1654
Loa Loa (eye worm) hypothetical protein 0.0497 0.0789 0.0785
Schistosoma mansoni tyrosine kinase 0.1001 0.1944 0.5283
Loa Loa (eye worm) hypothetical protein 0.0654 0.115 0.1147
Echinococcus multilocularis rho associated protein kinase 0.0863 0.1629 0.1646
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0308 0.0358 0.0354
Echinococcus multilocularis mitogen activated protein kinase 14 0.1019 0.1986 0.2007
Trypanosoma cruzi cdc2-related kinase 1 0.0308 0.0358 0.1335
Loa Loa (eye worm) TK/KIN16 protein kinase 0.1888 0.3978 0.3976
Schistosoma mansoni serine/threonine protein kinase 0.0254 0.0233 0.0616
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0325 0.0396 0.0846
Echinococcus granulosus tyrosine protein kinase Btk29A 0.116 0.2309 0.4974
Echinococcus multilocularis tyrosine protein kinase Fyn 0.049 0.0774 0.0779
Echinococcus multilocularis protein kinase shaggy 0.0592 0.1008 0.1017
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0254 0.0233 0.1452
Schistosoma mansoni cell adhesion molecule 0.0171 0.0042 0.0095
Schistosoma mansoni tyrosine kinase 0.1755 0.3674 1
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0331 0.041 0.1615
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0717 0.1295 0.2786
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.098 0.1897 0.1916
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0254 0.0233 0.1452
Brugia malayi RhoGAP domain containing protein 0.0164 0.0026 0.0021
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0656 0.1155 0.5579
Trichomonas vaginalis AGC family protein kinase 0.0206 0.0122 0.0613
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0171 0.0042 0.0038
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0939 0.1802 0.1821
Echinococcus multilocularis serine:threonine protein kinase 38 0.0186 0.0076 0.0073
Loa Loa (eye worm) hypothetical protein 0.0303 0.0344 0.034
Leishmania major protein kinase A catalytic subunit isoform 1 0.0331 0.041 0.1615
Brugia malayi Protein kinase domain containing protein 0.0186 0.0076 0.0072
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.07 0.1254 0.1251
Plasmodium vivax calcium-dependent protein kinase, putative 0.0254 0.0233 0.0868
Entamoeba histolytica protein kinase, putative 0.0182 0.0068 0.0361
Echinococcus multilocularis TGF beta receptor type 1 0.0464 0.0713 0.0718
Brugia malayi Immunoglobulin I-set domain containing protein 0.0171 0.0042 0.0038
Onchocerca volvulus 0.0193 0.0092 0.0092
Entamoeba histolytica protein kinase, putative 0.05 0.0796 0.5934
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0949 0.1824 0.1821
Schistosoma mansoni protein kinase 0.0513 0.0826 0.2232
Brugia malayi Protein kinase domain containing protein 0.0407 0.0583 0.0579
Trichomonas vaginalis AGC family protein kinase 0.0202 0.0115 0.0569
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0876 0.1658 0.1654
Echinococcus granulosus hypothetical protein 0.0579 0.0978 0.2101
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Brugia malayi Protein kinase domain containing protein 0.1775 0.3718 0.3716
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0876 0.1658 0.8252
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0162 0.0022 0.0018
Leishmania major protein kinase, putative 0.0254 0.0233 0.0672
Echinococcus granulosus cyclin dependent kinase 9 0.0173 0.0048 0.0095
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.1019 0.1986 1
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0281 0.0295 0.0291
Brugia malayi Protein kinase domain containing protein 0.0788 0.1456 0.1452
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0308 0.0358 0.2607
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0308 0.0358 0.0354
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0407 0.0583 0.0579
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.1019 0.1986 0.1983
Brugia malayi hypothetical protein 0.0242 0.0206 0.0202
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0226 0.017 0.0168
Echinococcus multilocularis 0.0579 0.0978 0.0986
Onchocerca volvulus 0.0863 0.1629 0.1629
Schistosoma mansoni tyrosine kinase 0.0374 0.0509 0.1368
Toxoplasma gondii histone kinase SNF1, putative 0.0199 0.0107 0.0283
Echinococcus multilocularis MAM 0.0182 0.0069 0.0065
Leishmania major protein kinase, putative 0.0656 0.1155 0.5579
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0242 0.0206 0.0541
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0224 0.0592
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0107 0.0272
Loa Loa (eye worm) hypothetical protein 0.0893 0.1698 0.1694
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0164 0.0026 0.005
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0949 0.1824 0.1843
Onchocerca volvulus Tyrosine kinase homolog 0.1592 0.3299 0.3299
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0592 0.1008 0.4797
Echinococcus multilocularis roundabout 2 0.0512 0.0824 0.083
Trypanosoma cruzi cdc2-related kinase 3 0.0308 0.0358 0.1335
Echinococcus granulosus roundabout 2 0.0171 0.0042 0.0082
Trichomonas vaginalis STE family protein kinase 0.0633 0.11 0.6595
Echinococcus granulosus insulin receptor 0.0677 0.1202 0.2586
Schistosoma mansoni serine/threonine protein kinase 0.0177 0.0058 0.0137
Loa Loa (eye worm) hypothetical protein 0.0199 0.0107 0.0103
Schistosoma mansoni nephrin 0.0456 0.0696 0.188
Echinococcus multilocularis protein kinase c epsilon type 0.025 0.0224 0.0223
Brugia malayi Immunoglobulin I-set domain containing protein 0.1888 0.3978 0.3976
Schistosoma mansoni protein kinase 0.0281 0.0295 0.0785
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0254 0.0233 0.0232
Loa Loa (eye worm) hypothetical protein 0.0331 0.041 0.0406
Plasmodium falciparum serine/threonine protein kinase, putative 0.05 0.0796 0.6577
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0242 0.0206 0.0526
Echinococcus multilocularis mitogen activated protein kinase 14 0.1019 0.1986 0.2007
Schistosoma mansoni tyrosine kinase 0.049 0.0774 0.209
Loa Loa (eye worm) hypothetical protein 0.0432 0.0641 0.0637
Echinococcus multilocularis G protein coupled receptor kinase 6 0.07 0.1254 0.1266
Schistosoma mansoni protein kinase 0.0851 0.1602 0.4349
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0254 0.0233 0.0868
Onchocerca volvulus 0.0204 0.0117 0.0117
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0638 0.1113 0.111
Loa Loa (eye worm) hypothetical protein 0.0225 0.0167 0.0163
Brugia malayi Variant SH3 domain containing protein 0.0175 0.0051 0.0047
Plasmodium falciparum calcium-dependent protein kinase 3 0.0254 0.0233 0.1204
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.1019 0.1986 1
Echinococcus granulosus roundabout 2 0.0171 0.0042 0.0082
Schistosoma mansoni tyrosine kinase 0.066 0.1163 0.3151
Schistosoma mansoni tyrosine kinase 0.0211 0.0134 0.0346
Entamoeba histolytica protein kinase domain containing protein 0.05 0.0796 0.5934
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0254 0.0233 0.0494
Echinococcus granulosus c-Jun N-terminal kinases 0.1322 0.268 0.5775
Brugia malayi serine/threonine protein kinase 6 0.05 0.0796 0.0792
Schistosoma mansoni adapter molecule crk 0.0175 0.0051 0.0121
Plasmodium falciparum calcium-dependent protein kinase 4 0.0254 0.0233 0.1204
Giardia lamblia Kinase, NEK 0.0633 0.11 0.6595
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0254 0.0233 0.0229
Echinococcus multilocularis tyrosine protein kinase Fyn 0.049 0.0774 0.0779
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0592 0.1008 0.8639
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.041 0.1099
Loa Loa (eye worm) TK protein kinase 0.076 0.1392 0.1388
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.1064 0.209 0.2087
Loa Loa (eye worm) hypothetical protein 0.0182 0.0069 0.0065
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0949 0.1824 0.1821
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0281 0.0295 0.0291
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0254 0.0233 0.0232
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1019 0.1986 1
Echinococcus granulosus protein kinase C gamma type 0.0186 0.0076 0.0156
Echinococcus multilocularis plexin a4 0.0157 0.001 0.0006
Schistosoma mansoni serine/threonine protein kinase 0.0384 0.0531 0.1429
Trypanosoma cruzi casein kinase, putative 0.0281 0.0295 0.1002
Giardia lamblia Kinase, CMGC CLK 0.0656 0.1155 0.6929
Brugia malayi Protein kinase domain containing protein 0.0186 0.0076 0.0072
Loa Loa (eye worm) hypothetical protein 0.0344 0.0439 0.0435
Brugia malayi Prion-like- 0.0156 0.0007 0.0003
Schistosoma mansoni tyrosine kinase 0.0282 0.0297 0.079
Brugia malayi Protein kinase domain containing protein 0.0225 0.0167 0.0163
Trichomonas vaginalis CMGC family protein kinase 0.0592 0.1008 0.6031
Echinococcus multilocularis dual specificity mitogen activated protein 0.0876 0.1658 0.1674
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0175 0.0051 0.0121
Echinococcus granulosus protein kinase c epsilon type 0.025 0.0224 0.0475
Brugia malayi serine/threonine-protein kinase PAK 7 0.1064 0.209 0.2087
Schistosoma mansoni tyrosine kinase 0.0225 0.0167 0.0437
Echinococcus multilocularis mitogen activated protein kinase 11 0.1019 0.1986 0.2007
Echinococcus granulosus serine:threonine protein kinase N2 0.0186 0.0076 0.0156
Entamoeba histolytica protein kinase, putative 0.0182 0.0068 0.0361
Plasmodium vivax glycogen synthase kinase 3, putative 0.0592 0.1008 0.8546
Echinococcus granulosus tyrosine protein kinase Src64B 0.049 0.0774 0.1661
Schistosoma mansoni serine/threonine protein kinase 0.0922 0.1763 0.4788
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0186 0.0076 0.0072
Giardia lamblia Kinase, CMGC CDK 0.0308 0.0358 0.2053
Loa Loa (eye worm) TK/ROR protein kinase 0.0226 0.017 0.0166
Entamoeba histolytica protein kinase domain containing protein 0.0732 0.1328 1
Echinococcus granulosus lachesin 0.0156 0.0007 0.0007
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0471 0.0731 0.0727
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.055 0.0911 0.428
Echinococcus granulosus defective proboscis extension response 0.0341 0.0432 0.0924
Loa Loa (eye worm) hypothetical protein 0.0171 0.0042 0.0038
Schistosoma mansoni protein kinase 0.0851 0.1602 0.4349
Leishmania major protein kinase, putative 0.05 0.0796 0.3669
Entamoeba histolytica PH domain containing protein kinase, putative 0.0351 0.0456 0.3332
Schistosoma mansoni serine/threonine protein kinase 0.05 0.0796 0.2152
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0922 0.1763 0.1759
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0254 0.0233 0.0672
Entamoeba histolytica serine/threonine protein kinase, putative 0.0199 0.0107 0.0661
Loa Loa (eye worm) AUR protein kinase 0.05 0.0796 0.0792
Schistosoma mansoni serine/threonine protein kinase 0.0287 0.0308 0.0819
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0633 0.11 0.9493
Echinococcus granulosus dual specificity testis-specific protein kinase 0.1205 0.2412 0.5196
Echinococcus granulosus neuroglian 0.0441 0.0661 0.1419
Giardia lamblia Kinase, CMGC GSK 0.0592 0.1008 0.6031
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0414 0.06 0.0603
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0331 0.041 0.1615
Trichomonas vaginalis STE family protein kinase 0.0876 0.1658 1
Echinococcus multilocularis mitogen activated protein kinase 11 0.1019 0.1986 0.2007
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0308 0.0358 0.1335
Echinococcus multilocularis protein kinase c iota type 0.025 0.0224 0.0223
Plasmodium falciparum calcium-dependent protein kinase 2 0.0254 0.0233 0.1204
Giardia lamblia Kinase, CAMK CAMKL 0.0216 0.0145 0.0755
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.066 0.1163 0.1173
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0592 0.1008 0.1005
Loa Loa (eye worm) TK protein kinase 0.0315 0.0373 0.0369
Echinococcus multilocularis casein kinase I alpha 0.0281 0.0295 0.0295
Brugia malayi SRC-1 0.049 0.0774 0.077
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.041 0.1099
Echinococcus granulosus casein kinase i 0.0281 0.0295 0.0628
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0171 0.0042 0.0082
Leishmania major protein kinase, putative 0.0656 0.1155 0.5579
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0175 0.0051 0.0047
Schistosoma mansoni serine/threonine protein kinase 0.0717 0.1295 0.3512
Echinococcus granulosus fibroblast growth factor receptor 4 0.066 0.1163 0.25
Schistosoma mansoni tyrosine kinase 0.049 0.0774 0.209
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0226 0.017 0.0357
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.032 0.0383 0.0818
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0156 0.0007 0.0003
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0358 0.2053
Brugia malayi Immunoglobulin I-set domain containing protein 0.0254 0.0233 0.0229
Loa Loa (eye worm) hypothetical protein 0.0157 0.0011 0.0007
Trypanosoma brucei protein kinase, putative 0.0204 0.0118 0.0061
Entamoeba histolytica protein kinase, putative 0.0206 0.0122 0.0778
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0331 0.041 0.1615
Loa Loa (eye worm) plexin A 0.0157 0.001 0.0006
Trichomonas vaginalis STE family protein kinase 0.0876 0.1658 1
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Brugia malayi Protein kinase domain containing protein 0.0922 0.1763 0.1759
Onchocerca volvulus 0.0225 0.0167 0.0167
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0156 0.0007 0.0003
Trichomonas vaginalis CK1 family protein kinase 0.0281 0.0295 0.1671
Echinococcus multilocularis hemicentin 1 0.0156 0.0007 0.0003
Brugia malayi Immunoglobulin I-set domain containing protein 0.0193 0.0092 0.0088
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0633 0.11 0.9458
Echinococcus multilocularis calcium dependent protein kinase 0.0177 0.0055 0.0052
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0242 0.0206 0.0435
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0325 0.0396 0.0392
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0592 0.1008 0.1017
Trichomonas vaginalis STE family protein kinase 0.0876 0.1658 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0331 0.041 0.0406
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Loa Loa (eye worm) hypothetical protein 0.0182 0.0069 0.0065
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0656 0.1155 0.5579
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0162 0.0022 0.0018
Echinococcus granulosus titin 0.0193 0.0092 0.0191
Schistosoma mansoni serine/threonine protein kinase 0.0656 0.1155 0.3131
Entamoeba histolytica PH domain containing protein kinase, putative 0.0351 0.0456 0.3332
Trichomonas vaginalis AGC family protein kinase 0.05 0.0796 0.4735
Giardia lamblia Kinase, CMGC CDK 0.0308 0.0358 0.2053
Echinococcus multilocularis Immunoglobulin 0.0341 0.0432 0.0434
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0331 0.041 0.0877
Echinococcus granulosus TGF-beta receptor type-1 0.0464 0.0713 0.1531
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0331 0.041 0.0406
Onchocerca volvulus 0.0225 0.0167 0.0167
Brugia malayi P38 map kinase family protein 2 0.1019 0.1986 0.1983
Onchocerca volvulus 0.0329 0.0405 0.0405
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0331 0.041 0.0877
Echinococcus granulosus serine:threonine protein kinase TAO1 0.1296 0.262 0.5646
Echinococcus multilocularis NCK adaptor protein 0.0183 0.0071 0.0068
Echinococcus granulosus tyrosine protein kinase otk 0.0156 0.0007 0.0007
Schistosoma mansoni cell adhesion molecule 0.0171 0.0042 0.0095
Entamoeba histolytica protein kinase, putative 0.0732 0.1328 1
Echinococcus granulosus cyclin dependent kinase 19 0.0922 0.1763 0.3796
Brugia malayi cyclin-dependent kinase 9 0.0173 0.0048 0.0044
Echinococcus multilocularis epidermal growth factor receptor 0.0374 0.0509 0.0511
Loa Loa (eye worm) TK/FAK protein kinase 0.1775 0.3718 0.3716
Echinococcus multilocularis tyrosine protein kinase Abl 0.0636 0.1107 0.1117
Echinococcus granulosus NCK adaptor protein 0.0175 0.0051 0.0102
Plasmodium falciparum protein kinase 5 0.0308 0.0358 0.2392
Toxoplasma gondii casein kinase I 0.0281 0.0295 0.2028
Trypanosoma cruzi cdc2-related kinase 3 0.0308 0.0358 0.1335
Toxoplasma gondii AGC kinase 0.0331 0.041 0.3096
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0242 0.0206 0.0541
Leishmania major casein kinase, putative 0.0281 0.0295 0.1002
Loa Loa (eye worm) hypothetical protein 0.0618 0.1067 0.1063
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0107 0.0272
Entamoeba histolytica protein kinase domain containing protein 0.0173 0.0048 0.0215
Echinococcus granulosus dual specificity 0.0732 0.1328 0.2857
Entamoeba histolytica protein kinase, putative 0.0162 0.0022 0.0012
Loa Loa (eye worm) SRC-1 0.049 0.0774 0.077
Echinococcus multilocularis cyclin dependent kinase 9 0.0173 0.0048 0.0045
Trypanosoma cruzi casein kinase, putative 0.0281 0.0295 0.1002
Echinococcus multilocularis lachesin 0.0156 0.0007 0.0003
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0118 0.0061
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0254 0.0233 0.0229
Onchocerca volvulus 0.0592 0.1008 0.1008
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.049 0.0774 0.0779
Echinococcus multilocularis casein kinase I delta 0.0281 0.0295 0.0295
Entamoeba histolytica protein kinase domain containing protein 0.0592 0.1008 0.7556
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0464 0.0713 0.0718
Schistosoma mansoni tyrosine kinase 0.0248 0.0219 0.0578
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0407 0.0583 0.0579
Echinococcus granulosus activated cdc42 kinase 1 0.102 0.1987 0.428
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0692 0.1237 0.2661
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0199 0.0107 0.0103
Schistosoma mansoni serine/threonine protein kinase 0.0949 0.1824 0.4956
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.032 0.0383 0.0384
Echinococcus multilocularis tyrosine protein kinase HCK 0.0315 0.0373 0.0374
Echinococcus multilocularis titin 0.0193 0.0092 0.0089
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0592 0.1008 0.4797
Schistosoma mansoni serine/threonine protein kinase 0.0331 0.041 0.1099
Loa Loa (eye worm) hypothetical protein 0.0461 0.0707 0.0703
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0788 0.1456 0.147
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0162 0.0022 0.0038
Schistosoma mansoni protein kinase 0.0851 0.1602 0.4349
Leishmania major protein kinase A catalytic subunit 0.0331 0.041 0.1615
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0171 0.0042 0.0038
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0254 0.0233 0.0868
Onchocerca volvulus 0.0394 0.0553 0.0553
Leishmania major protein kinase, putative 0.0204 0.0118 0.0061
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Brugia malayi Protein kinase domain containing protein 0.2522 0.5431 0.5429
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0173 0.0048 0.0044
Loa Loa (eye worm) hypothetical protein 0.0341 0.0432 0.0428
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0331 0.041 0.0411
Trypanosoma brucei aurora B kinase 0.05 0.0796 0.3669
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0254 0.0233 0.0494
Schistosoma mansoni serine/threonine protein kinase 0.0173 0.0048 0.0112
Brugia malayi protein-tyrosine kinase 0.0414 0.06 0.0596
Entamoeba histolytica protein kinase, putative 0.0254 0.0233 0.1627
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0308 0.0358 0.0354
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0007 0.0003
Schistosoma mansoni protein kinase 0.0204 0.0118 0.0303
Brugia malayi protein C17H12.11 0.0329 0.0406 0.0402
Echinococcus multilocularis protein KINase family member (kin 25) 0.047 0.0729 0.0734
Echinococcus granulosus mitogen activated protein kinase 11 0.1019 0.1986 0.4277
Schistosoma mansoni protein kinase 0.0162 0.0022 0.004
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0186 0.0076 0.0072
Echinococcus multilocularis dual specificity testis specific protein kinase 0.1205 0.2412 0.2438
Echinococcus multilocularis PAK box P21 Rho binding 0.0162 0.0022 0.0018
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0949 0.1824 0.1824
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0177 0.0055 0.0268
Trypanosoma cruzi cdc2-related kinase 1 0.0308 0.0358 0.1335
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0876 0.1658 0.8252
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0341 0.0432 0.116
Trichomonas vaginalis AGC family protein kinase 0.0206 0.0122 0.0613
Echinococcus granulosus casein kinase I alpha 0.0281 0.0295 0.0628
Echinococcus multilocularis casein kinase i 0.0281 0.0295 0.0295
Trichomonas vaginalis AGC family protein kinase 0.05 0.0796 0.4735
Echinococcus granulosus epidermal growth factor receptor 0.0374 0.0509 0.1089
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0331 0.041 0.0411
Brugia malayi Cam kinase protein 1 0.0254 0.0233 0.0229
Echinococcus multilocularis tyrosine protein kinase otk 0.0156 0.0007 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0732 0.1328 0.3602
Plasmodium falciparum protein kinase, putative 0.0204 0.0118 0.0109
Schistosoma mansoni serine/threonine protein kinase 0.0546 0.0901 0.2437
Echinococcus granulosus protein kinase shaggy 0.0592 0.1008 0.2167
Echinococcus granulosus mitogen activated protein kinase 14 0.1019 0.1986 0.4277
Trichomonas vaginalis AGC family protein kinase 0.0186 0.0076 0.0333
Loa Loa (eye worm) AGC/AKT protein kinase 0.0206 0.0122 0.0118
Echinococcus multilocularis growth factor receptor bound protein 2 0.0175 0.0051 0.0048
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0331 0.041 0.0411
Echinococcus multilocularis serine:threonine protein kinase N2 0.0186 0.0076 0.0073
Plasmodium vivax serine/threonine kinase-1, putative 0.0656 0.1155 1
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0156 0.0007 0.0007
Loa Loa (eye worm) hypothetical protein 0.0156 0.0007 0.0003
Brugia malayi intracellular kinase 0.0592 0.1008 0.1005
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0717 0.1295 0.1291
Echinococcus multilocularis N chimaerin 0.0164 0.0026 0.0022
Loa Loa (eye worm) hypothetical protein 0.0329 0.0405 0.0401
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Echinococcus multilocularis aurora kinase A 0.05 0.0796 0.0802
Schistosoma mansoni protein kinase 0.1205 0.2412 0.6558
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0331 0.041 0.1615
Entamoeba histolytica protein kinase, putative 0.0186 0.0076 0.0428
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.1296 0.262 0.2617
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.0732 0.1328 0.6498
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0281 0.0295 0.0291
Entamoeba histolytica protein kinase, putative 0.0592 0.1008 0.7556
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.049 0.0774 0.1661
Brugia malayi Temporarily assigned gene name protein 59 0.0242 0.0206 0.0202
Loa Loa (eye worm) TK/ABL protein kinase 0.11 0.2171 0.2168
Brugia malayi Protein kinase domain containing protein 0.0429 0.0634 0.063
Giardia lamblia Kinase, CK1 Casein kinase 0.0281 0.0295 0.1671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0171 0.0042 0.0038
Trypanosoma brucei cdc2-related kinase 3 0.0308 0.0358 0.1335
Plasmodium falciparum protein serine/threonine kinase-1 0.0656 0.1155 1
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0164 0.0026 0.0046
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0254 0.0233 0.0494
Echinococcus multilocularis dual specificity protein kinase clk2 0.0656 0.1155 0.1165
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0358 0.2053
Brugia malayi Variant SH3 domain containing protein 0.0164 0.0026 0.0021
Echinococcus granulosus dual specificity mitogen activated protein 0.0876 0.1658 0.3568
Echinococcus granulosus N chimaerin 0.0164 0.0026 0.0046
Loa Loa (eye worm) AUR protein kinase 0.05 0.0796 0.0792
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0204 0.0118 0.0389
Echinococcus granulosus tyrosine protein kinase Blk 0.0414 0.06 0.1286
Loa Loa (eye worm) hypothetical protein 0.0414 0.0599 0.0595
Schistosoma mansoni serine/threonine protein kinase 0.0281 0.0295 0.0785
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Schistosoma mansoni protein kinase 0.0876 0.1658 0.4501
Schistosoma mansoni titin 0.0193 0.0092 0.0232
Giardia lamblia Kinase, NEK 0.0633 0.11 0.6595
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0301 0.0341 0.0911
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.098 0.1897 0.4084
Echinococcus multilocularis c Jun NH2 terminal kinase 0.1322 0.268 0.2709
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0414 0.06 0.1286
Echinococcus multilocularis cyclin dependent kinase 5 0.0308 0.0358 0.0358
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Echinococcus granulosus tyrosine protein kinase ABL1 0.11 0.2171 0.4676
Echinococcus multilocularis tyrosine protein kinase Fgr 0.049 0.0774 0.0779
Plasmodium falciparum NIMA related kinase 1 0.0633 0.11 0.9478
Entamoeba histolytica hypothetical protein 0.0732 0.1328 1
Loa Loa (eye worm) AGC/PKN protein kinase 0.0186 0.0076 0.0072
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0186 0.0076 0.0156
Onchocerca volvulus 0.0414 0.0599 0.0599
Loa Loa (eye worm) hypothetical protein 0.0231 0.018 0.0176
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0224 0.0592
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.2522 0.5431 0.5429
Entamoeba histolytica protein kinase, putative 0.0315 0.0373 0.2698
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.07 0.1254 0.1251
Brugia malayi serine/threonine kinase 12 0.05 0.0796 0.0792
Brugia malayi Serine/threonine-protein kinase SULU 0.1296 0.262 0.2617
Giardia lamblia Kinase, CMGC GSK 0.0592 0.1008 0.6031
Echinococcus granulosus cyclin dependent kinase 0.0308 0.0358 0.0763
Schistosoma mansoni serine/threonine protein kinase 0.0191 0.0088 0.0222
Echinococcus multilocularis dual specificity 0.0732 0.1328 0.134
Loa Loa (eye worm) hypothetical protein 0.0579 0.0978 0.0974
Onchocerca volvulus 0.0166 0.0032 0.0032
Echinococcus granulosus protein tyrosine kinase 0.1755 0.3674 0.792
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0007 0.0003
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0171 0.0042 0.0038
Echinococcus granulosus casein kinase I alpha 0.0281 0.0295 0.0628
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.05 0.0796 0.0802
Echinococcus granulosus epidermal growth factor receptor 0.0374 0.0509 0.1089
Loa Loa (eye worm) hypothetical protein 0.0242 0.0206 0.0202
Plasmodium falciparum calcium-dependent protein kinase 1 0.0254 0.0233 0.1204
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.049 0.0774 0.1661
Schistosoma mansoni growth factor receptor-bound protein 0.0175 0.0051 0.0121
Echinococcus multilocularis tyrosine protein kinase ABL1 0.11 0.2171 0.2194
Trichomonas vaginalis CK1 family protein kinase 0.0281 0.0295 0.1671
Schistosoma mansoni tyrosine kinase 0.0248 0.0219 0.0578
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0656 0.1155 0.5579
Echinococcus granulosus tyrosine protein kinase Fyn 0.049 0.0774 0.1661
Plasmodium vivax serine/threonine protein kinase 6, putative 0.05 0.0796 0.6446
Entamoeba histolytica casein kinase 1, putative 0.0281 0.0295 0.2101
Echinococcus multilocularis cyclin dependent kinase 9 0.019 0.0087 0.0084
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.0076 0.0188
Entamoeba histolytica protein kinase, putative 0.0732 0.1328 1
Loa Loa (eye worm) AGC/PKA protein kinase 0.0331 0.041 0.0406
Brugia malayi Protein kinase domain containing protein 0.0308 0.0358 0.0354
Trypanosoma brucei protein kinase, putative 0.0592 0.1008 0.4797
Loa Loa (eye worm) hypothetical protein 0.047 0.0729 0.0725
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0254 0.0233 0.0868
Onchocerca volvulus 0.0786 0.1452 0.1452
Echinococcus multilocularis tyrosine protein kinase Fyn 0.049 0.0774 0.0779
Trichomonas vaginalis AGC family protein kinase 0.05 0.0796 0.4735
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0638 0.1113 0.1123
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0769 0.1413 0.1409
Giardia lamblia Kinase, AGC PKA 0.0331 0.041 0.2375
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.1322 0.268 0.2677
Brugia malayi protein kinase C II. 0.025 0.0224 0.022
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0296 0.033 0.033
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.049 0.0774 0.0779
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0656 0.1155 0.1152
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0171 0.0042 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0638 0.1113 0.3016
Loa Loa (eye worm) AUR protein kinase 0.05 0.0796 0.0792
Loa Loa (eye worm) hypothetical protein 0.251 0.5403 0.5401
Loa Loa (eye worm) hypothetical protein 0.0344 0.0439 0.0435
Schistosoma mansoni protein kinase C mu 0.0471 0.0731 0.1974
Echinococcus multilocularis cyclin dependent kinase 19 0.0922 0.1763 0.1781
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0331 0.041 0.1615
Trichomonas vaginalis AGC family protein kinase 0.0206 0.0122 0.0613
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Echinococcus multilocularis tyrosine protein kinase Blk 0.0414 0.06 0.0603
Giardia lamblia Kinase, CAMK CAMKL 0.0216 0.0145 0.0755
Brugia malayi Protein kinase domain containing protein 0.0206 0.0122 0.0118
Echinococcus multilocularis 0.0401 0.0569 0.0572
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0242 0.0206 0.0204
Trypanosoma brucei cdc2-related kinase 1 0.0308 0.0358 0.1335
Echinococcus multilocularis fibroblast growth factor receptor 4 0.066 0.1163 0.1173
Entamoeba histolytica protein kinase domain containing protein 0.0204 0.0118 0.0749
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.1296 0.262 0.2649
Schistosoma mansoni nck2/grb4 0.0175 0.0051 0.0121
Brugia malayi Protein kinase domain containing protein 0.0325 0.0396 0.0392
Loa Loa (eye worm) hypothetical protein 0.0242 0.0206 0.0202
Loa Loa (eye worm) AGC/NDR protein kinase 0.0186 0.0076 0.0072
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0331 0.041 0.1615
Schistosoma mansoni tyrosine kinase 0.0301 0.0341 0.0911
Schistosoma mansoni vav2 0.0183 0.0071 0.0175
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.1019 0.1986 1
Toxoplasma gondii AGC kinase 0.0331 0.041 0.3096
Schistosoma mansoni growth factor receptor-bound protein 0.0183 0.0071 0.0174
Echinococcus granulosus aurora kinase A 0.05 0.0796 0.171
Echinococcus granulosus peroxidasin 0.0157 0.0011 0.0016
Trypanosoma brucei rac serine-threonine kinase, putative 0.0206 0.0122 0.0081
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.05 0.0796 0.5934
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0341 0.0432 0.0434
Echinococcus granulosus serine:threonine protein kinase 12 B 0.05 0.0796 0.171
Brugia malayi casein kinase 1, delta 0.0281 0.0295 0.0291
Schistosoma mansoni serine/threonine protein kinase 0.098 0.1897 0.5154
Brugia malayi Tyrosine-protein kinase abl-1 0.0636 0.1107 0.1104
Brugia malayi hypothetical protein 0.0182 0.0069 0.0065
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0513 0.0826 0.0822
Echinococcus granulosus protein kinase 0.0401 0.0569 0.122
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0597 0.102 0.1016
Loa Loa (eye worm) hypothetical protein 0.0654 0.115 0.1147
Trichomonas vaginalis AGC family protein kinase 0.0206 0.0122 0.0613
Echinococcus multilocularis epidermal growth factor receptor 0.0374 0.0509 0.0511
Trichomonas vaginalis AGC family protein kinase 0.05 0.0796 0.4735
Brugia malayi SH2 domain containing protein 0.0225 0.0167 0.0163
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0656 0.1155 0.5579
Echinococcus multilocularis neuroglian 0.0441 0.0661 0.0666
Schistosoma mansoni protein kinase 0.0401 0.0569 0.1533
Brugia malayi Variant SH3 domain containing protein 0.0175 0.0051 0.0047
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Echinococcus granulosus tyrosine protein kinase shark 0.0225 0.0167 0.0352
Echinococcus multilocularis activin receptor type 0.2176 0.4638 0.4691
Echinococcus multilocularis Protein kinase C, brain isozyme 0.025 0.0224 0.0223
Brugia malayi hypothetical protein 0.0329 0.0406 0.0402
Echinococcus granulosus contactin 0.0171 0.0042 0.0082
Brugia malayi cyclin-dependent kinase 7 homolog 0.0508 0.0816 0.0812
Echinococcus granulosus activin receptor type 0.2176 0.4638 1
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.07 0.1254 0.1251
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0162 0.0022 0.0018
Schistosoma mansoni tyrosine kinase 0.0677 0.1202 0.326
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0331 0.041 0.1615
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.098 0.1897 0.1894
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0007 0.0003
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0107 0.0272
Trichomonas vaginalis AGC family protein kinase 0.0206 0.0122 0.0613
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0732 0.1328 0.6498
Echinococcus granulosus tyrosine protein kinase Btk29A 0.047 0.0729 0.1563
Loa Loa (eye worm) hypothetical protein 0.0156 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0397 0.056 0.0556
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0565 0.0946 0.2034
Echinococcus granulosus tyrosine protein kinase HCK 0.0315 0.0373 0.0796
Brugia malayi protein unc-22 0.0193 0.0092 0.0088
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.07 0.1254 0.2698
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.0732 0.1328 0.1324
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.0076 0.0188
Echinococcus multilocularis cyclin dependent kinase 7 0.0492 0.0777 0.0783
Echinococcus multilocularis Immunoglobulin 0.0341 0.0432 0.0434
Schistosoma mansoni serine/threonine protein kinase 0.0186 0.0076 0.0188
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0788 0.1456 0.1452
Echinococcus multilocularis cyclin dependent kinase 0.0308 0.0358 0.0358
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0254 0.0233 0.1452
Loa Loa (eye worm) hypothetical protein 0.0156 0.0007 0.0003
Brugia malayi Protein kinase domain containing protein 0.0225 0.0167 0.0163
Trypanosoma brucei casein kinase I, isoform 2 0.0281 0.0295 0.1002
Echinococcus multilocularis protein tyrosine kinase 0.1755 0.3674 0.3715
Schistosoma mansoni protein kinase 0.1205 0.2412 0.6558
Schistosoma mansoni serine/threonine protein kinase 0.0863 0.1629 0.4424
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0656 0.1155 0.5579
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0492 0.0777 0.0774
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Giardia lamblia Kinase, AGC AKT 0.053 0.0865 0.5157
Echinococcus granulosus twitchin 0.0519 0.0839 0.1802
Onchocerca volvulus 0.0198 0.0104 0.0104
Brugia malayi plexin A 0.0157 0.001 0.0006
Echinococcus multilocularis serine:threonine protein kinase N2 0.0186 0.0076 0.0073
Loa Loa (eye worm) hypothetical protein 0.0497 0.0789 0.0785
Schistosoma mansoni tyrosine kinase 0.1093 0.2155 0.5857
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0597 0.102 0.1016
Schistosoma mansoni hypothetical protein 0.0182 0.0069 0.0168
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0851 0.1602 0.3448
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0204 0.0117 0.0057
Brugia malayi Protein kinase domain containing protein 0.0949 0.1824 0.1821
Echinococcus multilocularis activated cdc42 kinase 1 0.102 0.1987 0.2008
Echinococcus granulosus raf serine:threonine protein kinase 0.0191 0.0088 0.0182
Brugia malayi Protein kinase domain containing protein 0.098 0.1897 0.1894
Loa Loa (eye worm) gastrulation defective protein 1 0.0844 0.1585 0.1582
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.0732 0.1328 0.6498
Brugia malayi Protein kinase domain 0.0162 0.0022 0.0018
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0331 0.041 0.0411
Loa Loa (eye worm) hypothetical protein 0.0156 0.0007 0.0003
Schistosoma mansoni rap gtpase-activating protein 0.0242 0.0206 0.0541
Echinococcus multilocularis casein kinase I alpha 0.0281 0.0295 0.0295
Loa Loa (eye worm) hypothetical protein 0.0356 0.0467 0.0463
Schistosoma mansoni protein kinase 0.0464 0.0713 0.1926
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0254 0.0233 0.0229
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0949 0.1824 0.1821
Echinococcus granulosus Vam6:Vps39 protein 0.0242 0.0206 0.0435
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0171 0.0042 0.0038
Echinococcus granulosus cyclin dependent kinase 7 0.0492 0.0777 0.1669
Loa Loa (eye worm) hypothetical protein 0.0565 0.0946 0.0943
Loa Loa (eye worm) hypothetical protein 0.0356 0.0467 0.0463
Schistosoma mansoni tyrosine kinase 0.0248 0.0219 0.0578
Echinococcus multilocularis tyrosine protein kinase Src64B 0.049 0.0774 0.0779
Trypanosoma cruzi casein kinase, putative 0.0281 0.0295 0.1002
Brugia malayi Furin-like cysteine rich region family protein 0.0374 0.0509 0.0505
Schistosoma mansoni serine/threonine protein kinase 0.1296 0.262 0.7127
Brugia malayi ribosomal protein S6 kinase alpha 3 0.053 0.0865 0.0862
Brugia malayi Peroxidasin 0.0157 0.0011 0.0007
Echinococcus multilocularis hemicentin 1 0.0156 0.0007 0.0003
Brugia malayi Stress-activated protein kinase jnk-1 0.1322 0.268 0.2677
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Echinococcus granulosus cyclin dependent kinase 9 0.019 0.0087 0.0179
Echinococcus multilocularis insulin receptor 0.0677 0.1202 0.1213
Echinococcus multilocularis tyrosine protein kinase shark 0.0225 0.0167 0.0165
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0717 0.1295 0.1291
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0254 0.0233 0.0493
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0225 0.0167 0.0352
Brugia malayi p70 ribosomal S6 kinase beta 0.0186 0.0076 0.0072
Echinococcus granulosus hemicentin 1 0.0156 0.0007 0.0007
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.05 0.0796 0.5934
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.066 0.1163 0.25
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0331 0.041 0.0877
Trypanosoma cruzi casein kinase, putative 0.0281 0.0295 0.1002
Echinococcus granulosus MAM 0.0182 0.0069 0.0139
Loa Loa (eye worm) TK/INSR protein kinase 0.0677 0.1202 0.1199
Schistosoma mansoni protein kinase 0.05 0.0796 0.2152
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0384 0.0531 0.1137
Loa Loa (eye worm) hypothetical protein 0.0254 0.0233 0.0229
Brugia malayi Protein kinase domain containing protein 0.282 0.6113 0.6111
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0384 0.0531 0.0534
Echinococcus granulosus tyrosine kinase 0.0225 0.0167 0.0352
Brugia malayi C1-like domain containing protein 0.0471 0.0731 0.0727
Echinococcus multilocularis tyrosine kinase 0.0225 0.0167 0.0165
Brugia malayi Tyrosine-protein kinase abl-1 0.054 0.0888 0.0884
Echinococcus multilocularis death associated protein kinase 1 0.4464 0.9881 1
Brugia malayi probable protein kinase 0.0643 0.1124 0.112
Echinococcus granulosus cyclin dependent kinase 5 0.0308 0.0358 0.0763
Echinococcus granulosus titin 0.0193 0.0092 0.0191
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0186 0.0076 0.0156
Giardia lamblia Aurora kinase 0.05 0.0796 0.4735
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Loa Loa (eye worm) hypothetical protein 0.0242 0.0206 0.0202
Echinococcus multilocularis serine threonine protein kinase 0.0186 0.0076 0.0073
Loa Loa (eye worm) hypothetical protein 0.0156 0.0007 0.0003
Echinococcus granulosus tyrosine protein kinase Srms 0.0225 0.0167 0.0352
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0949 0.1824 0.3929
Entamoeba histolytica cell division protein kinase 2, putative 0.0325 0.0396 0.2874
Loa Loa (eye worm) hypothetical protein 0.0343 0.0437 0.0433
Onchocerca volvulus 0.0225 0.0167 0.0167
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0248 0.022 0.0216
Schistosoma mansoni vesicular amine transporter 0.0341 0.0432 0.116
Schistosoma mansoni serine/threonine protein kinase 0.0384 0.0531 0.1429
Schistosoma mansoni tyrosine kinase 0.0677 0.1202 0.326
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0331 0.041 0.2624
Plasmodium falciparum calcium-dependent protein kinase 5 0.0254 0.0233 0.1204
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0331 0.041 0.3096
Loa Loa (eye worm) hypothetical protein 0.0182 0.0069 0.0065
Echinococcus granulosus tyrosine protein kinase Lyn 0.0568 0.0951 0.2044
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0374 0.0509 0.1089
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0007 0.0003
Schistosoma mansoni protein kinase 0.0162 0.0022 0.004
Schistosoma mansoni serine/threonine protein kinase 0.1322 0.268 0.729
Schistosoma mansoni cell adhesion molecule 0.0412 0.0595 0.1602
Trichomonas vaginalis AGC family protein kinase 0.0206 0.0122 0.0613
Echinococcus granulosus calcium dependent protein kinase 0.0177 0.0055 0.0111
Brugia malayi Protein kinase domain containing protein 0.0225 0.0167 0.0163
Brugia malayi Protein kinase domain containing protein 0.102 0.1987 0.1984
Brugia malayi Immunoglobulin I-set domain containing protein 0.076 0.1392 0.1388
Echinococcus granulosus cyclin dependent kinase 1 0.0308 0.0358 0.0763
Giardia lamblia Kinase, STE STE20 0.0876 0.1658 1
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.1881 0.3962 0.8542
Entamoeba histolytica protein kinase, putative 0.05 0.0796 0.5934
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.049 0.0774 0.0779
Brugia malayi Protein kinase domain containing protein 0.0732 0.1328 0.1324
Brugia malayi bone morphogenetic protein type 1 receptor 0.0513 0.0826 0.0822
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0717 0.1295 0.1307
Echinococcus granulosus tyrosine protein kinase Src42A 0.0296 0.033 0.0703
Brugia malayi Sex muscle abnormal protein 5 0.0175 0.0051 0.0047
Entamoeba histolytica protein kinase, putative 0.0186 0.0076 0.0428
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0692 0.1237 0.1249
Echinococcus multilocularis casein kinase I alpha 0.0281 0.0295 0.0295
Onchocerca volvulus Slit protein homolog 0.0154 0.0004 0.0004
Echinococcus granulosus tyrosine kinase 0.0414 0.06 0.1286
Echinococcus granulosus growth factor receptor bound protein 2 0.0183 0.0071 0.0145
Echinococcus multilocularis c src tyrosine kinase 0.0301 0.0341 0.0341
Trichomonas vaginalis CMGC family protein kinase 0.0308 0.0358 0.2053
Trichomonas vaginalis CMGC family protein kinase 0.0592 0.1008 0.6031
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.0777 0.2101
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0281 0.0295 0.1002
Loa Loa (eye worm) hypothetical protein 0.0175 0.0051 0.0047
Trichomonas vaginalis AGC family protein kinase 0.0331 0.041 0.2375
Loa Loa (eye worm) hypothetical protein 0.0329 0.0405 0.0401
Trichomonas vaginalis CAMK family protein kinase 0.0254 0.0233 0.1291
Trichomonas vaginalis AGC family protein kinase 0.0633 0.11 0.6595
Brugia malayi Protein kinase domain containing protein 0.0656 0.1155 0.1152
Echinococcus granulosus Protein kinase C brain isozyme 0.025 0.0224 0.0475
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0656 0.1155 0.5579
Schistosoma mansoni protein kinase 0.0643 0.1124 0.3046
Loa Loa (eye worm) TK protein kinase 0.0414 0.06 0.0596
Schistosoma mansoni tyrosine kinase 0.0301 0.0341 0.0911
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0341 0.0432 0.116
Trypanosoma cruzi aurora B kinase, putative 0.05 0.0796 0.3669
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0325 0.0396 0.0396
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0164 0.0026 0.0021
Entamoeba histolytica protein kinase domain containing protein 0.0592 0.1008 0.7556
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0193 0.0092 0.0088
Onchocerca volvulus 0.0182 0.0069 0.0069
Schistosoma mansoni serine/threonine protein kinase 0.0492 0.0777 0.2101
Loa Loa (eye worm) hypothetical protein 0.0432 0.0641 0.0637
Schistosoma mansoni serine/threonine protein kinase 0.0193 0.0092 0.0232
Brugia malayi serine/threonine-protein kinase 6 0.05 0.0796 0.0792
Schistosoma mansoni kinase 0.0173 0.0048 0.0112
Echinococcus multilocularis casein kinase I delta 0.0281 0.0295 0.0295
Toxoplasma gondii aurora kinase 0.05 0.0796 0.6674
Echinococcus granulosus tyrosine protein kinase Fyn 0.049 0.0774 0.1661
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Echinococcus granulosus neuroglian 0.0171 0.0042 0.0082
Echinococcus granulosus activated cdc42 kinase 1 0.102 0.1987 0.428
Loa Loa (eye worm) hypothetical protein 0.0329 0.0406 0.0402
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0471 0.0731 0.0727
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0242 0.0206 0.0526
Entamoeba histolytica protein kinase, putative 0.0162 0.0022 0.0012
Schistosoma mansoni hypothetical protein 0.0182 0.0069 0.0168
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0162 0.0022 0.0038
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0769 0.1413 0.1409
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0186 0.0076 0.0072
Schistosoma mansoni tyrosine kinase 0.0374 0.0509 0.1368
Onchocerca volvulus 0.0242 0.0206 0.0206
Echinococcus multilocularis cyclin dependent kinase 1 0.0308 0.0358 0.0358
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0118 0.0061
Echinococcus granulosus plexin a4 0.0157 0.001 0.0013
Echinococcus granulosus dual specificity protein kinase clk2 0.0656 0.1155 0.2484
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0397 0.056 0.1199
Brugia malayi hypothetical protein 0.0225 0.0167 0.0163
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0308 0.0358 0.0763
Loa Loa (eye worm) TK/EGFR protein kinase 0.0374 0.0509 0.0505
Entamoeba histolytica protein kinase, putative 0.0254 0.0233 0.1627
Trichomonas vaginalis AGC family protein kinase 0.0186 0.0076 0.0333
Entamoeba histolytica protein kinase, putative 0.0177 0.0055 0.0268
Entamoeba histolytica protein kinase, putative 0.0206 0.0122 0.0778
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0358 0.0956
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.116 0.2309 0.2333
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0162 0.0022 0.0038
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0254 0.0233 0.0231
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0254 0.0233 0.0229
Brugia malayi Protein kinase domain containing protein 0.0225 0.0167 0.0163
Schistosoma mansoni vam6/vps39 related 0.0242 0.0206 0.0541
Echinococcus multilocularis raf serine:threonine protein kinase 0.0191 0.0088 0.0085
Brugia malayi hypothetical protein 0.0356 0.0467 0.0463
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0186 0.0076 0.0073
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0638 0.1113 0.2394
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0186 0.0076 0.0073
Entamoeba histolytica protein kinase , putative 0.05 0.0796 0.5934
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0175 0.0051 0.0047
Echinococcus granulosus NDR protein kinase 0.0186 0.0076 0.0156
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.025 0.0224 0.022
Trichomonas vaginalis CK1 family protein kinase 0.0281 0.0295 0.1671
Brugia malayi Immunoglobulin I-set domain containing protein 0.0171 0.0042 0.0038
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0407 0.0583 0.0579
Loa Loa (eye worm) hypothetical protein 0.0497 0.0789 0.0785
Onchocerca volvulus 0.0225 0.0167 0.0167
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0592 0.1008 0.2731
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0225 0.0167 0.1125
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Schistosoma mansoni protein kinase 0.0162 0.0022 0.004
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0592 0.1008 0.1005
Schistosoma mansoni hypothetical protein 0.0242 0.0206 0.0541
Trichomonas vaginalis CMGC family protein kinase 0.0656 0.1155 0.6929
Brugia malayi SH2 domain containing protein 0.0225 0.0167 0.0163
Echinococcus multilocularis tyrosine protein kinase Srms 0.0414 0.06 0.0603
Onchocerca volvulus 0.1365 0.278 0.278
Echinococcus granulosus protein kinase c iota type 0.025 0.0224 0.0475
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0225 0.0167 0.0165
Schistosoma mansoni serine/threonine protein kinase 0.0199 0.0107 0.0272
Schistosoma mansoni tyrosine kinase 0.0374 0.0509 0.1368
Schistosoma mansoni nephrin 0.0171 0.0042 0.0095
Echinococcus granulosus casein kinase I alpha 0.0281 0.0295 0.0628
Onchocerca volvulus 0.0281 0.0295 0.0295
Brugia malayi cell division control protein 2 homolog 0.0308 0.0358 0.0354
Plasmodium vivax protein kinase Crk2 0.0308 0.0358 0.2102
Onchocerca volvulus 0.0432 0.0641 0.0641
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0242 0.0206 0.0526
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0851 0.1602 0.1618
Echinococcus granulosus Immunoglobulin 0.0341 0.0432 0.0924
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0199 0.0107 0.0104
Echinococcus multilocularis roundabout 2 0.0171 0.0042 0.0038
Echinococcus granulosus c src tyrosine kinase 0.0301 0.0341 0.0727
Onchocerca volvulus 0.0225 0.0167 0.0167
Brugia malayi Fibronectin type III domain containing protein 0.0356 0.0467 0.0463
Echinococcus granulosus tyrosine protein kinase Src42A 0.049 0.0774 0.1661
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0331 0.041 0.2895
Onchocerca volvulus 0.0225 0.0167 0.0167
Loa Loa (eye worm) hypothetical protein 0.0394 0.0553 0.0549
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0164 0.0026 0.0022
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.05 0.0796 0.5934
Echinococcus granulosus casein kinase I delta 0.0281 0.0295 0.0628
Brugia malayi casein kinase I 0.0281 0.0295 0.0291
Brugia malayi Hr1 repeat family protein 0.0186 0.0076 0.0072
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Loa Loa (eye worm) hypothetical protein 0.0341 0.0432 0.0428
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Loa Loa (eye worm) hypothetical protein 0.0432 0.0641 0.0637
Brugia malayi Immunoglobulin I-set domain containing protein 0.0356 0.0467 0.0463
Echinococcus multilocularis roundabout 2 0.0171 0.0042 0.0038
Schistosoma mansoni serine/threonine protein kinase 0.0656 0.1155 0.3131
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Entamoeba histolytica p21-activated kinase 0.0182 0.0068 0.0361
Loa Loa (eye worm) TK/FER protein kinase 0.0225 0.0167 0.0163
Schistosoma mansoni tyrosine kinase 0.047 0.0729 0.1967
Plasmodium vivax casein kinase 1, putative 0.0281 0.0295 0.1483
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0308 0.0358 0.1335
Trypanosoma cruzi casein kinase, putative 0.0281 0.0295 0.1002
Schistosoma mansoni serine/threonine kinase 0.0186 0.0076 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0769 0.1413 0.3833
Loa Loa (eye worm) CAMK protein kinase 0.0193 0.0092 0.0088
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.0732 0.1328 0.6498
Brugia malayi putative serine/threonine kinase SADA gamma 0.0199 0.0107 0.0103
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0656 0.1155 1
Giardia lamblia Kinase, NEK 0.0633 0.11 0.6595
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0171 0.0042 0.0038
Plasmodium falciparum casein kinase 1 0.0281 0.0295 0.1796
Echinococcus multilocularis neuroglian 0.0171 0.0042 0.0038
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0876 0.1658 0.8252
Echinococcus multilocularis tyrosine protein kinase Src42A 0.049 0.0774 0.0779
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0401 0.0569 0.0565
Echinococcus granulosus casein kinase I delta 0.0281 0.0295 0.0628
Schistosoma mansoni atypical protein kinase C 0.025 0.0224 0.0592
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0254 0.0233 0.0232
Echinococcus multilocularis transfer RNA-Thr 0.102 0.1987 0.2008
Leishmania major protein kinase A catalytic subunit isoform 2 0.0331 0.041 0.1615
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0788 0.1456 0.3133
Echinococcus granulosus serine:threonine kinase SAD 1 0.0199 0.0107 0.0222
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0156 0.0007 0.0003
Loa Loa (eye worm) hypothetical protein 0.0156 0.0007 0.0003
Echinococcus granulosus rho-associated protein kinase 1 0.0863 0.1629 0.3508
Brugia malayi hypothetical protein 0.1296 0.262 0.2617
Loa Loa (eye worm) hypothetical protein 0.102 0.1987 0.1984
Brugia malayi Protein kinase domain containing protein 0.0225 0.0167 0.0163
Echinococcus granulosus TGF beta receptor type 1 0.0464 0.0713 0.1531
Entamoeba histolytica cell division protein kinase 2, putative 0.0308 0.0358 0.258
Echinococcus multilocularis twitchin 0.0177 0.0058 0.0054
Echinococcus multilocularis peroxidasin 0.0157 0.0011 0.0007
Schistosoma mansoni neuroglian 0.0171 0.0042 0.0095
Schistosoma mansoni serine/threonine protein kinase 0.0308 0.0358 0.0956
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0007 0.0003
Loa Loa (eye worm) TK/ALK protein kinase 0.2819 0.6111 0.6109
Trichomonas vaginalis AGC family protein kinase 0.0206 0.0122 0.0613
Schistosoma mansoni serine/threonine protein kinase 0.025 0.0224 0.0592
Echinococcus granulosus roundabout 2 0.0512 0.0824 0.1769
Trichomonas vaginalis AGC family protein kinase 0.0206 0.0122 0.0613
Brugia malayi Protein kinase domain containing protein 0.0677 0.1202 0.1199
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0592 0.1008 0.2167
Echinococcus granulosus tyrosine protein kinase Fyn 0.049 0.0774 0.1661
Loa Loa (eye worm) hypothetical protein 0.0356 0.0467 0.0463
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0204 0.0118 0.0061
Echinococcus multilocularis cyclin dependent kinase 1 0.0308 0.0358 0.0358
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0164 0.0026 0.005
Trichomonas vaginalis CAMK family protein kinase 0.0199 0.0107 0.052
Brugia malayi Immunoglobulin I-set domain containing protein 0.0156 0.0007 0.0003

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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