Detailed information for compound 1468476

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 337.399 | Formula: C18H21N6O+
  • H donors: 2 H acceptors: 0 LogP: 2.53 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: NC(=N)N/N=C/c1ccc(cc1)OCc1cn2c([n+]1C)cc(cc2)C
  • InChi: 1S/C18H21N6O/c1-13-7-8-24-11-15(23(2)17(24)9-13)12-25-16-5-3-14(4-6-16)10-21-22-18(19)20/h3-11H,12H2,1-2H3,(H4,19,20,22)/q+1/b21-10+
  • InChiKey: FXCDXBHYLUTPPF-UFFVCSGVSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.1102 0.1151
Echinococcus multilocularis cathepsin b 0.0284 0.869 1
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.1272 0.1272
Giardia lamblia Cathepsin B precursor 0.0094 0.251 1
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0491 0.5
Loa Loa (eye worm) mbt repeat family protein 0.0051 0.113 0.111
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0041 0.0813 0.0813
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0253 0.0222
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0764 0.0797
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0813 0.0813
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Brugia malayi Bromodomain containing protein 0.0045 0.0926 0.1031
Schistosoma mansoni hypothetical protein 0.0052 0.1149 0.1199
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0813 0.0813
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0089 0.2355 0.2458
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.3258 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0036 0.0631 0.0524
Echinococcus granulosus histone lysine methyltransferase setb 0.005 0.1102 0.1207
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0948 0.0948
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0223 0.6725 0.769
Trypanosoma brucei PAB1-binding protein , putative 0.0027 0.0346 0.0346
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0948 0.0948
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0604 0.0604
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0284 0.869 0.9071
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0089 0.2355 0.2658
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.113 0.118
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0061 0.0064
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0202 0.6022 0.6909
Loa Loa (eye worm) PHD-finger family protein 0.0031 0.0483 0.0349
Echinococcus granulosus histone acetyltransferase KAT2B 0.0151 0.438 0.5005
Loa Loa (eye worm) hypothetical protein 0.0058 0.136 0.1381
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.3258 0.3823
Plasmodium falciparum histone acetyltransferase GCN5 0.0042 0.0829 1
Loa Loa (eye worm) hypothetical protein 0.0069 0.1701 0.1782
Schistosoma mansoni hypothetical protein 0.0311 0.958 1
Trypanosoma brucei unspecified product 0.0029 0.0395 0.0395
Mycobacterium tuberculosis Conserved hypothetical protein 0.0171 0.5015 1
Echinococcus granulosus peregrin 0.0038 0.069 0.0728
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0395 0.0395
Toxoplasma gondii ImpB/MucB/SamB family protein 0.004 0.0773 0.1973
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0346 0.0346
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0253 0.0264
Trypanosoma brucei unspecified product 0.0029 0.0395 0.0395
Loa Loa (eye worm) phosphofructokinase 0.0117 0.3258 0.3612
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0764 0.0797
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0764 0.0814
Toxoplasma gondii cathepsin B 0.0094 0.251 1
Echinococcus multilocularis histone acetyltransferase MYST2 0.0058 0.136 0.1506
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0058 0.136 0.1506
Brugia malayi 6-phosphofructokinase 0.0117 0.3258 0.3724
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.005 0.1102 0.1151
Echinococcus multilocularis lysine specific demethylase 5A 0.0038 0.0697 0.0737
Onchocerca volvulus 0.0051 0.113 0.0893
Echinococcus multilocularis dna polymerase kappa 0.0041 0.0813 0.0871
Trypanosoma cruzi DNA polymerase eta, putative 0.0069 0.1701 0.1701
Echinococcus multilocularis geminin 0.0182 0.5376 0.616
Loa Loa (eye worm) hypothetical protein 0.0031 0.0483 0.0349
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0031 0.0483 0.0504
Brugia malayi Bromodomain containing protein 0.0038 0.069 0.0758
Echinococcus granulosus polycomb protein SCMH1 0.0051 0.113 0.1239
Loa Loa (eye worm) hypothetical protein 0.0194 0.5763 0.6558
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.0508 0.053
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Leishmania major ATP-dependent phosphofructokinase 0.0117 0.3258 0.3258
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0089 0.2355 0.2658
Echinococcus granulosus zinc finger protein 0.0025 0.0273 0.0246
Schistosoma mansoni hypothetical protein 0.0182 0.5376 0.5612
Loa Loa (eye worm) cathepsin B 0.0094 0.251 0.2733
Brugia malayi PHD-finger family protein 0.0031 0.0483 0.0519
Entamoeba histolytica deoxycytidyl transferase, putative 0.0041 0.0813 0.1164
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0764 0.0679
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Toxoplasma gondii hypothetical protein 0.0052 0.1165 0.3788
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.0508 0.0749
Brugia malayi 6-phosphofructokinase 0.0117 0.3258 0.3724
Leishmania major DNA polymerase eta, putative 0.004 0.0773 0.0773
Trichomonas vaginalis set domain proteins, putative 0.0254 0.7728 1
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.3258 0.3823
Brugia malayi N-terminal motif family protein 0.0194 0.5763 0.6619
Schistosoma mansoni bromodomain containing protein 0.0072 0.1797 0.1876
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0158 0.4604 0.5265
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0041 0.0813 0.0871
Loa Loa (eye worm) hypothetical protein 0.0054 0.121 0.1204
Echinococcus multilocularis survival motor neuron protein 1 0.0254 0.7714 0.8869
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0068 0.1672 0.1867
Loa Loa (eye worm) hypothetical protein 0.005 0.1078 0.1049
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0324 1 1
Brugia malayi hypothetical protein 0.0027 0.0346 0.036
Echinococcus granulosus cathepsin b 0.0284 0.869 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.0508 0.0517
Trypanosoma cruzi DNA polymerase eta, putative 0.004 0.0773 0.0773
Loa Loa (eye worm) hypothetical protein 0.0048 0.1011 0.097
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0202 0.6022 0.6909
Schistosoma mansoni rotamase 0.0036 0.0631 0.0659
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0284 0.869 0.869
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0035 0.0604 0.0604
Brugia malayi mbt repeat family protein 0.0051 0.113 0.1266
Entamoeba histolytica acetyltransferase, GNAT family 0.0042 0.0829 0.1224
Giardia lamblia DINP protein human, muc B family 0.0041 0.0813 0.1625
Brugia malayi acetyltransferase, GNAT family protein 0.0158 0.4604 0.528
Schistosoma mansoni methyl-cpg binding protein mbd 0.0018 0.0061 0.0064
Trypanosoma brucei unspecified product 0.0041 0.0813 0.0813
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0058 0.136 0.1506
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0395 0.0395
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0089 0.2355 0.2681
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0089 0.2355 0.2658
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0881 0.0951
Onchocerca volvulus 0.0052 0.1149 0.0918
Brugia malayi Bromodomain containing protein 0.0084 0.2206 0.2509
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.3258 0.3612
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Echinococcus multilocularis 6 phosphofructokinase 0.0117 0.3258 0.3704
Brugia malayi ImpB/MucB/SamB family protein 0.0041 0.0813 0.09
Schistosoma mansoni myelin transcription factor 1 myt1 0.0058 0.136 0.142
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0051 0.113 0.118
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0094 0.251 0.251
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0036 0.0631 0.069
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0032 0.0491 0.5
Brugia malayi Pre-SET motif family protein 0.0032 0.0508 0.0547
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0102 0.2797 0.317
Echinococcus granulosus histone acetyltransferase MYST2 0.0058 0.136 0.1506
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Echinococcus multilocularis PHD finger protein rhinoceros 0.0031 0.0483 0.0489
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0041 0.0813 0.0737
Brugia malayi cathepsin B-like cysteine proteinase 0.0284 0.869 1
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0089 0.2355 0.2658
Loa Loa (eye worm) hypothetical protein 0.0089 0.2355 0.255
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0035 0.0604 0.0604
Echinococcus granulosus survival motor neuron protein 1 0.0254 0.7714 0.8869
Leishmania major DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.3258 0.34
Loa Loa (eye worm) hypothetical protein 0.0027 0.0346 0.0188
Schistosoma mansoni hypothetical protein 0.0089 0.2355 0.2458
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.3258 0.3823
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0491 0.3
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0041 0.0813 0.0848
Echinococcus multilocularis zinc finger protein 0.0025 0.0273 0.0246
Loa Loa (eye worm) hypothetical protein 0.0076 0.1933 0.2054
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.3258 1
Trichomonas vaginalis rotamase, putative 0.0036 0.0631 0.0194
Trypanosoma brucei DNA polymerase eta, putative 0.0069 0.1701 0.1701
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0158 0.4604 0.4806
Loa Loa (eye worm) acetyltransferase 0.0158 0.4604 0.5196
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0284 0.869 0.9071
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0881 0.0951
Loa Loa (eye worm) hypothetical protein 0.0254 0.7714 0.8853
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0051 0.113 0.0893
Echinococcus granulosus 6 phosphofructokinase 0.0117 0.3258 0.3704
Trichomonas vaginalis conserved hypothetical protein 0.0036 0.0631 0.0194
Loa Loa (eye worm) MBCTL1 0.0058 0.136 0.1381
Giardia lamblia Histone acetyltransferase GCN5 0.0042 0.0829 0.1707
Trypanosoma brucei DNA polymerase kappa, putative 0.0029 0.0395 0.0395
Entamoeba histolytica phosphofructokinase, putative 0.0117 0.3258 1
Plasmodium falciparum phd finger protein, putative 0.0031 0.0483 0.2847
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.0508 0.053
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Echinococcus multilocularis cathepsin b 0.0284 0.869 1
Trypanosoma brucei DNA polymerase IV, putative 0.0041 0.0813 0.0813
Schistosoma mansoni hypothetical protein 0.0031 0.0483 0.0504
Echinococcus granulosus dna polymerase kappa 0.0041 0.0813 0.0871
Brugia malayi ImpB/MucB/SamB family protein 0.0069 0.1701 0.1926
Echinococcus granulosus cathepsin b 0.0284 0.869 1
Loa Loa (eye worm) hypothetical protein 0.005 0.1102 0.1078
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Echinococcus multilocularis SAM and MBT domain containing protein 0.0051 0.113 0.1239
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.3258 0.3258
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0948 0.0948
Toxoplasma gondii phosphofructokinase PFKII 0.0032 0.0491 0.067
Loa Loa (eye worm) hypothetical protein 0.0284 0.869 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0032 0.0491 0.3
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0052 0.1149 0.1288
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0117 0.3258 0.3258
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0048 0.1036 0.3188
Brugia malayi PHD-finger family protein 0.0031 0.0459 0.0491
Brugia malayi Pre-SET motif family protein 0.0223 0.6725 0.7731
Schistosoma mansoni 6-phosphofructokinase 0.0117 0.3258 0.34
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0284 0.869 0.9071
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0094 0.251 0.279
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0068 0.1672 0.1867
Echinococcus granulosus geminin 0.0182 0.5376 0.616
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0948 0.0948
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0035 0.0604 0.0604
Schistosoma mansoni DNA polymerase eta 0.0069 0.1701 0.1776
Schistosoma mansoni hypothetical protein 0.0089 0.2355 0.2458
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0094 0.251 0.262
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0483 0.0636
Brugia malayi phosphofructokinase 0.0117 0.3258 0.3724
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0041 0.0813 0.0445
Echinococcus granulosus histone acetyltransferase KAT2B 0.0048 0.1036 0.1129
Onchocerca volvulus 0.0032 0.0508 0.0034
Leishmania major hypothetical protein, conserved 0.0027 0.0346 0.0346
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0117 0.3258 0.5818
Echinococcus granulosus expressed protein 0.0036 0.0631 0.0661
Brugia malayi hypothetical protein 0.0254 0.7714 0.8873
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0491 0.2102
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.4452 0.4452
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0117 0.3258 0.5
Schistosoma mansoni zinc finger protein 0.0025 0.0273 0.0285
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0153 0.4452 0.4452
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Schistosoma mansoni hypothetical protein 0.0089 0.2355 0.2458
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.072 0.0763
Loa Loa (eye worm) 6-phosphofructokinase 0.0117 0.3258 0.3612
Echinococcus multilocularis expressed protein 0.0036 0.0631 0.0661
Giardia lamblia Cathepsin B precursor 0.0094 0.251 1
Echinococcus granulosus dna polymerase eta 0.0069 0.1701 0.1901
Leishmania major DNA polymerase eta, putative 0.0069 0.1701 0.1701
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0117 0.3258 1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0094 0.251 0.251
Echinococcus granulosus PHD finger protein rhinoceros 0.0031 0.0483 0.0489
Echinococcus multilocularis dna polymerase eta 0.0069 0.1701 0.1901
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0094 0.251 0.251
Toxoplasma gondii 6-phosphofructokinase 0.0032 0.0491 0.067
Brugia malayi mbt repeat family protein 0.0051 0.113 0.1266
Schistosoma mansoni survival motor neuron protein 0.0052 0.1149 0.1199
Trichomonas vaginalis rotamase, putative 0.0035 0.0604 0.0157
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0035 0.0604 0.041
Loa Loa (eye worm) bromodomain containing protein 0.0023 0.0206 0.0024
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0041 0.0813 0.0871
Schistosoma mansoni hypothetical protein 0.0182 0.5376 0.5612
Brugia malayi jmjC domain containing protein 0.0102 0.2797 0.3192
Toxoplasma gondii PHD-finger domain-containing protein 0.0031 0.0483 0.0636
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0253 0.0222
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.072 0.0763
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0153 0.4452 0.4452
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0058 0.136 0.1532
Toxoplasma gondii peptidylprolyl isomerase 0.0035 0.0604 0.1194
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Loa Loa (eye worm) hypothetical protein 0.0051 0.113 0.111
Echinococcus multilocularis polycomb protein SCMH1 0.0051 0.113 0.1239
Trichomonas vaginalis phosphofructokinase, putative 0.0117 0.3258 0.3823
Mycobacterium ulcerans hypothetical protein 0.0171 0.5015 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0284 0.869 0.9071
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0102 0.2797 0.317
Loa Loa (eye worm) jmjC domain-containing protein 0.0065 0.1566 0.1623
Schistosoma mansoni jumonji domain containing protein 0.0081 0.2112 0.2205
Schistosoma mansoni terminal deoxycytidyl transferase 0.0041 0.0813 0.0848
Trichomonas vaginalis DNA polymerase eta, putative 0.0041 0.0813 0.0445
Plasmodium vivax 6-phosphofructokinase, putative 0.0032 0.0491 0.2102
Plasmodium vivax SET domain protein, putative 0.0032 0.0508 0.2348
Schistosoma mansoni hypothetical protein 0.0022 0.0186 0.0194
Trichomonas vaginalis bromodomain-containing protein, putative 0.0048 0.1036 0.0753
Schistosoma mansoni sex comb on midleg homolog 0.0051 0.113 0.118
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0483 0.1995
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0048 0.1036 0.0753
Loa Loa (eye worm) hypothetical protein 0.0041 0.0805 0.0727
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.005 0.1102 0.1207
Trypanosoma cruzi PAB1-binding protein , putative 0.0027 0.0346 0.0346
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0032 0.0491 0.0036
Giardia lamblia Cathepsin B precursor 0.0094 0.251 1
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0324 1 1
Schistosoma mansoni apoptosis regulator bax 0.0089 0.2355 0.2458
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0324 1 1
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.0469 0.0473
Trypanosoma cruzi DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Trypanosoma brucei DNA polymerase kappa, putative 0.0041 0.0813 0.0813
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0194 0.5763 0.7287
Echinococcus multilocularis peregrin 0.0038 0.069 0.0728
Loa Loa (eye worm) apoptosis regulator protein 0.0089 0.2355 0.255
Mycobacterium ulcerans 6-phosphofructokinase 0.0117 0.3258 0.5818
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0032 0.0491 0.067
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0048 0.1036 0.3188
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0048 0.1036 1
Brugia malayi jmjC domain containing protein 0.004 0.0764 0.0843
Onchocerca volvulus 0.0254 0.7728 1
Echinococcus granulosus SAM and MBT domain containing protein 0.0051 0.113 0.1239

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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