Detailed information for compound 1504011

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 409.424 | Formula: C16H22F3N3O4S
  • H donors: 2 H acceptors: 3 LogP: 2.75 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: O=C(Nc1ccc(cc1)OC(F)(F)F)NC1CCN(CC1)S(=O)(=O)C(C)C
  • InChi: 1S/C16H22F3N3O4S/c1-11(2)27(24,25)22-9-7-13(8-10-22)21-15(23)20-12-3-5-14(6-4-12)26-16(17,18)19/h3-6,11,13H,7-10H2,1-2H3,(H2,20,21,23)
  • InChiKey: BFHZANLWUWANDR-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens epoxide hydrolase 2, cytoplasmic Starlite/ChEMBL References

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Mycobacterium ulcerans epoxide hydrolase EphA Get druggable targets OG5_129061 All targets in OG5_129061
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) Get druggable targets OG5_129061 All targets in OG5_129061
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0029 0.0157 0.0216
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0105 0.1026 0.1284
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0157 0.0301
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.005 0.0391 0.0485
Trichomonas vaginalis glucose transporter, putative 0.0029 0.0157 0.0346
Trypanosoma brucei sugar transporter, putative 0.0029 0.0157 0.1426
Giardia lamblia Sugar-proton symporter 0.0029 0.0157 0.0346
Echinococcus granulosus synaptic vesicle 2 protein 0.0029 0.0157 0.019
Trypanosoma cruzi glucose transporter, putative 0.0029 0.0157 0.1426
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.005 0.0391 0.0686
Brugia malayi Melatonin receptor type 1A 0.005 0.0391 0.0766
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.005 0.0391 0.0492
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0157 0.0301
Toxoplasma gondii facilitative glucose transporter GT1 0.0208 0.2218 0.3266
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) 26S proteasome regulatory subunit rpn11 0.0024 0.0098 0.0183
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium tuberculosis Probable epoxide hydrolase EphA (epoxide hydratase) (arene-oxide hydratase) 0.0395 0.4366 1
Echinococcus granulosus neuropeptides capa receptor 0.005 0.0391 0.0485
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.028 0.2539
Leishmania major phosphopantetheinyl transferase-like protein 0.0024 0.0095 0.0866
Brugia malayi 6-phosphofructokinase 0.0111 0.1101 0.2175
Echinococcus granulosus serotonin receptor 0.005 0.0391 0.0485
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0024 0.003
Schistosoma mansoni sugar transporter 0.0029 0.0157 0.0197
Echinococcus granulosus lysine specific demethylase 5A 0.0042 0.0307 0.038
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.005 0.0391 0.0766
Schistosoma mansoni cpg binding protein 0.0033 0.02 0.0251
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0047 0.0043
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0062 0.0539 0.106
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni zinc finger protein 0.0022 0.007 0.0088
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0099 0.0024
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0007
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0086
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0391 0.0485
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0042 0.0303 0.0591
Loa Loa (eye worm) hypothetical protein 0.0064 0.0554 0.109
Brugia malayi beta-NAC-like protein 0.004 0.028 0.0544
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0111 0.1101 0.6276
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0099 0.0186
Leishmania major DNA polymerase kappa, putative 0.002 0.0047 0.0428
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1101 0.2914
Trypanosoma cruzi hexose transporter, putative 0.0029 0.0157 0.1426
Chlamydia trachomatis lysine--tRNA ligase 0.0046 0.0355 1
Onchocerca volvulus 0.005 0.0391 0.0686
Schistosoma mansoni glucose transport protein 0.0208 0.2218 0.2789
Echinococcus multilocularis neuropeptide s receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) bromodomain containing protein 0.0018 0.0028 0.0044
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0564 0.1466
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Onchocerca volvulus 0.005 0.0391 0.0686
Brugia malayi putative neuropeptide receptor 0.005 0.0391 0.0766
Onchocerca volvulus 0.0029 0.0157 0.0216
Leishmania major glucose transporter, lmgt1 0.0065 0.0564 0.512
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Schistosoma mansoni sugar transporter 0.0029 0.0157 0.0197
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0564 0.512
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0163 0.1697 1
Brugia malayi PHD-finger family protein 0.0027 0.0133 0.0252
Echinococcus granulosus somatostatin receptor 0.005 0.0391 0.0485
Schistosoma mansoni neuropeptide f receptor 76f 0.005 0.0391 0.0492
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.0391 0.0492
Onchocerca volvulus Matrilysin homolog 0.0044 0.0328 0.056
Echinococcus multilocularis 6 phosphofructokinase 0.0111 0.1101 0.1378
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0166 0.0108
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0163 0.1697 0.3864
Mycobacterium ulcerans sugar transporter 0.0029 0.0157 0.0296
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni alpha-1 adrenergic receptor 0.005 0.0391 0.0492
Schistosoma mansoni jumonji domain containing protein 0.0083 0.0778 0.0978
Loa Loa (eye worm) ICD-1 protein 0.004 0.028 0.0544
Loa Loa (eye worm) jmjC domain-containing protein 0.0042 0.0307 0.0599
Loa Loa (eye worm) hypothetical protein 0.0042 0.03 0.0584
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus orexin receptor type 2 0.005 0.0391 0.0485
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0046 0.0355 0.1622
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0489 0.0605
Echinococcus multilocularis neuropeptide receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0018 0.0028 0.0028
Onchocerca volvulus 0.0029 0.0157 0.0216
Echinococcus granulosus lysyl tRNA synthetase 0.0046 0.0355 0.044
Echinococcus granulosus metabotropic glutamate receptor 5 0.0202 0.214 0.2686
Onchocerca volvulus 0.0024 0.0099 0.01
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0062 0.0539 0.1361
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Onchocerca volvulus Huntingtin homolog 0.0125 0.1264 0.2434
Leishmania major ATP-dependent phosphofructokinase 0.0111 0.1101 1
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Echinococcus granulosus neuropeptide Y receptor 0.005 0.0391 0.0485
Toxoplasma gondii proteasome regulatory subunit 0.0024 0.0098 0.0004
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0186 0.1963 0.2469
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1101 1
Echinococcus multilocularis neuropeptide receptor A26 0.005 0.0391 0.0485
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0047 0.0059
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0047 0.0083
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0539 0.0678
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Entamoeba histolytica protein kinase, putative 0.0064 0.0554 0.1402
Brugia malayi G-protein coupled receptor 0.005 0.0391 0.0766
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0099 0.0163
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0024 0.0095 0.006
Trypanosoma cruzi hexose transporter, putative 0.0035 0.0226 0.2056
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0099 0.0189
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi major facilitator superfamily protein 0.0029 0.0157 0.0301
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Schistosoma mansoni metabotropic glutamate receptor 0.0137 0.1399 0.1759
Plasmodium vivax calcium-dependent protein kinase, putative 0.0064 0.0555 0.0528
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Plasmodium vivax basic transcription factor 3b, putative 0.004 0.028 0.0252
Onchocerca volvulus 0.005 0.0391 0.0686
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0099 0.0186
Brugia malayi jmjC domain containing protein 0.0042 0.0307 0.0599
Loa Loa (eye worm) hypothetical protein 0.0202 0.214 0.4241
Schistosoma mansoni opsin-like receptor 0.005 0.0391 0.0492
Toxoplasma gondii sugar transporter ST3 0.0029 0.0157 0.0095
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0021 0.0026
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus 7TM GPCR rhodopsin 0.005 0.0391 0.0485
Schistosoma mansoni protein kinase 0.0064 0.0554 0.0697
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0186
Brugia malayi Dopamine receptor protein 1 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.0125 0.1264 0.2499
Echinococcus multilocularis fmrfamide receptor 0.005 0.0391 0.0485
Onchocerca volvulus 0.0085 0.08 0.1504
Trypanosoma brucei glucose transporter 2A 0.0065 0.0564 0.512
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trichomonas vaginalis glucose transporter, putative 0.0065 0.0564 0.1466
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0307 0.0386
Mycobacterium ulcerans hydrolase 0.0024 0.0099 0.0162
Schistosoma mansoni hypothetical protein 0.0027 0.0126 0.0158
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0064 0.0554 0.069
Brugia malayi ORL1-like opioid receptor 0.005 0.0391 0.0766
Schistosoma mansoni histamine h1 receptor 0.005 0.0391 0.0492
Schistosoma mansoni protein kinase 0.0064 0.0554 0.0697
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0029 0.0157 0.1426
Echinococcus multilocularis allatostatin A receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis solute carrier family 22 0.0029 0.0157 0.019
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0095 0.0067
Onchocerca volvulus 0.005 0.0391 0.0686
Trichomonas vaginalis sugar transport protein, putative 0.0029 0.0157 0.0346
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0007
Toxoplasma gondii sugar transporter ST1 0.0029 0.0157 0.0095
Giardia lamblia Fructose-bisphosphate aldolase 0.0334 0.3663 1
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Echinococcus granulosus peregrin 0.0034 0.0216 0.0265
Brugia malayi Hemopexin family protein 0.0028 0.0145 0.0276
Brugia malayi RE15519p 0.005 0.0391 0.0766
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0166 0.0108
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0064 0.0555 0.0528
Brugia malayi Metabotropic glutamate receptor precursor. 0.0164 0.1705 0.3375
Schistosoma mansoni opsin-like receptor 0.005 0.0391 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0099 0.0144
Giardia lamblia PHD finger protein 15 0.0032 0.0188 0.0432
Giardia lamblia Hexose transporter 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0166 0.0328
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus g-protein coupled receptor 0.005 0.0391 0.0485
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.005 0.0391 0.0492
Plasmodium falciparum basic transcription factor 3b, putative 0.004 0.028 0.0252
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Echinococcus multilocularis tachykinin peptides receptor 99D 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.0391 0.0485
Onchocerca volvulus 0.005 0.0391 0.0686
Loa Loa (eye worm) hypothetical protein 0.0055 0.0451 0.0885
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.005 0.0391 0.0485
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0564 0.512
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi Matrix metalloprotease, N-terminal domain containing protein 0.0024 0.0099 0.0185
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.0208 0.2218 0.2784
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis solute carrier family 22 0.0029 0.0157 0.019
Onchocerca volvulus 0.005 0.0391 0.0686
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.0391 0.0766
Plasmodium falciparum calcium-dependent protein kinase 1 0.0064 0.0555 0.0528
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus solute carrier family 22 0.0029 0.0157 0.019
Onchocerca volvulus 0.005 0.0391 0.0686
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.0391 0.0492
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Brugia malayi Major Facilitator Superfamily protein 0.0029 0.0157 0.0301
Echinococcus granulosus dro:myosuppressin receptor 0.005 0.0391 0.0485
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1101 0.2945
Echinococcus multilocularis microtubule associated protein 2 0.0706 0.7953 1
Echinococcus multilocularis dna polymerase eta 0.002 0.0047 0.0052
Trypanosoma cruzi transcription factor btf3, putative 0.004 0.028 0.2539
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0099 0.0163
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0064 0.0554 0.109
Onchocerca volvulus 0.0029 0.0157 0.0216
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0099 0.0163
Schistosoma mansoni jumonji/arid domain-containing protein 0.0042 0.0307 0.0386
Schistosoma mansoni matrix metallopeptidase-7 (M10 family) 0.002 0.0049 0.0062
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0166 0.0138
Plasmodium falciparum protein kinase 7 0.0589 0.6597 0.6587
Brugia malayi Receptor family ligand binding region containing protein 0.0042 0.0303 0.0591
Echinococcus granulosus alpha 1A adrenergic receptor 0.005 0.0391 0.0485
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0148 0.1528 0.3023
Onchocerca volvulus 0.0029 0.0157 0.0216
Echinococcus granulosus General substrate transporter 0.0179 0.1881 0.236
Echinococcus multilocularis biogenic amine (5HT) receptor 0.005 0.0391 0.0485
Echinococcus multilocularis alpha 1A adrenergic receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Onchocerca volvulus 0.0029 0.0157 0.0216
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0099 0.0144
Loa Loa (eye worm) matrix metalloproteinase 0.002 0.0049 0.0086
Mycobacterium ulcerans hypothetical protein 0.0024 0.0099 0.0163
Echinococcus granulosus solute carrier family 22 0.0029 0.0157 0.019
Schistosoma mansoni cpg binding protein 0.0029 0.0158 0.0199
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0085 0.08 0.1577
Echinococcus granulosus sex peptide receptor 0.005 0.0391 0.0485
Plasmodium vivax proline--tRNA ligase, putative 0.0073 0.0659 0.0632
Plasmodium vivax sugar transporter, putative 0.0029 0.0157 0.0129
Plasmodium falciparum mitogen-activated protein kinase 2 0.0337 0.3696 0.3678
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1101 0.2945
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0018 0.0031 0.0284
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1101 0.2914
Giardia lamblia Prolyl-tRNA synthetase 0.0062 0.0539 0.1399
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0047 0.0069
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0099 0.0163
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Onchocerca volvulus Neuropeptide F receptor homolog 0.005 0.0391 0.0686
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) phosphofructokinase 0.0111 0.1101 0.2175
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.005 0.0391 0.0766
Brugia malayi AKH receptor 0.005 0.0391 0.0766
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus G protein coupled receptor 139 0.005 0.0391 0.0485
Brugia malayi major facilitator superfamily protein 0.0029 0.0157 0.0301
Toxoplasma gondii lysine-tRNA ligase 0.0046 0.0355 0.04
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0334 0.3663 1
Leishmania major glucose transporter/membrane transporter D2, putative 0.0065 0.0564 0.512
Loa Loa (eye worm) hypothetical protein 0.0125 0.1264 0.2499
Brugia malayi hypothetical protein 0.0029 0.0157 0.0301
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.005 0.0391 0.0492
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0105 0.1026 0.1284
Brugia malayi Sugar transporter family protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1101 0.2175
Echinococcus granulosus 6 phosphofructokinase 0.0111 0.1101 0.1378
Giardia lamblia Lysyl-tRNA synthetase 0.0046 0.0355 0.0892
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.0046 0.0355 0.0694
Onchocerca volvulus 0.0029 0.0157 0.0216
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0063 0.0543 0.0676
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0047 0.0428
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0028 0.0035
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0337 0.3696 0.5538
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.005 0.0391 0.0766
Brugia malayi neuropeptide F receptor 0.005 0.0391 0.0766
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0024 0.0098 0.0116
Schistosoma mansoni hypothetical protein 0.005 0.0391 0.0492
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0029 0.0157 0.0197
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0186
Onchocerca volvulus 0.0029 0.0157 0.0216
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0024 0.0095 0.0067
Echinococcus granulosus g protein coupled receptor 0.005 0.0391 0.0485
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0391 0.0485
Schistosoma mansoni sugar transporter 0.0029 0.0157 0.0197
Schistosoma mansoni adenoreceptor 0.005 0.0391 0.0492
Echinococcus multilocularis peregrin 0.0034 0.0216 0.0265
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0047 0.0364 0.0458
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus 26S proteasome regulatory subunit N11 0.0018 0.0031 0.0032
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0274 0.0592
Echinococcus granulosus allatostatin A receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.0072 0.0653 0.1286
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0037 0.0243 0.0299
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0064 0.0555 0.0706
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.0391 0.0766
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.005 0.0391 0.0492
Brugia malayi CXXC zinc finger family protein 0.0029 0.0158 0.0303
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0046 0.0355 0.0892
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0086
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0029 0.0157 0.0296
Leishmania major protein kinase, putative 0.0064 0.0554 0.5034
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0538 0.0676
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0064 0.0555 0.0706
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0062 0.0539 0.0672
Loa Loa (eye worm) hypothetical protein 0.0051 0.0404 0.0792
Echinococcus granulosus tm gpcr rhodopsin 0.005 0.0391 0.0485
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0564 0.1466
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Brugia malayi PHD-finger family protein 0.0032 0.0188 0.0362
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0221 0.0429
Echinococcus granulosus cpg binding protein 0.0033 0.02 0.0245
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Onchocerca volvulus 0.0029 0.0157 0.0216
Loa Loa (eye worm) hypothetical protein 0.0453 0.504 1
Loa Loa (eye worm) hypothetical protein 0.0039 0.0272 0.0529
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0099 0.0163
Loa Loa (eye worm) sugar transporter 0.0208 0.2218 0.4395
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0391 0.0492
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Echinococcus multilocularis G protein coupled receptor 139 0.005 0.0391 0.0485
Brugia malayi hypothetical protein 0.0029 0.0157 0.0301
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.005 0.0391 0.0766
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0355 0.0446
Echinococcus granulosus matrix metallopeptidase 7 M10 family 0.0072 0.0653 0.0815
Plasmodium falciparum calcium-dependent protein kinase 3 0.0064 0.0555 0.0528
Echinococcus multilocularis GPCR, family 3, C terminal 0.0027 0.0126 0.0151
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0047 0.0428
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0007
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0062 0.0539 0.2771
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0041 0.0289 0.071
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.0391 0.0485
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1101 0.1384
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0062 0.0539 0.106
Loa Loa (eye worm) 6-phosphofructokinase 0.0111 0.1101 0.2175
Plasmodium falciparum proline--tRNA ligase 0.0073 0.0659 0.0632
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0062 0.0539 0.1399
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0064 0.0554 0.5034
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0027 0.0126 0.0154
Onchocerca volvulus 0.0029 0.0157 0.0216
Toxoplasma gondii protein kinase, putative 0.0589 0.6597 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.005 0.0391 0.0485
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0407 0.0798
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0062 0.0539 0.0672
Loa Loa (eye worm) matrixin family protein 0.0048 0.0374 0.0732
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0024 0.0095 0.018
Loa Loa (eye worm) runx1 0.0057 0.0475 0.0931
Schistosoma mansoni transcription factor btf3 0.004 0.028 0.0351
Trichomonas vaginalis CAMK family protein kinase 0.0064 0.0554 0.144
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0202 0.214 0.2686
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Onchocerca volvulus 0.0029 0.0157 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Echinococcus granulosus neuropeptide receptor A26 0.005 0.0391 0.0485
Echinococcus granulosus microtubule associated protein 2 0.0706 0.7953 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus Sugar transporter ERD6 protein 0.0029 0.0157 0.019
Echinococcus granulosus g protein coupled receptor 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0027 0.0126 0.0239
Echinococcus granulosus dnaJ subfamily B 0.0419 0.464 0.5832
Brugia malayi phosphofructokinase 0.0111 0.1101 0.2175
Loa Loa (eye worm) hypothetical protein 0.0062 0.0539 0.106
Entamoeba histolytica protein kinase, putative 0.0064 0.0554 0.1402
Brugia malayi metabotropic glutamate receptor type 2 0.008 0.0739 0.1456
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0166 0.0256
Loa Loa (eye worm) hypothetical protein 0.002 0.0047 0.0083
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0047 0.0069
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0099 0.0186
Echinococcus multilocularis sex peptide receptor 0.005 0.0391 0.0485
Chlamydia trachomatis proline--tRNA ligase 0.0022 0.0074 0.139
Trypanosoma brucei proteasome regulatory non-ATPase subunit 11 0.0018 0.0031 0.0284
Loa Loa (eye worm) TYRA-2 protein 0.005 0.0391 0.0766
Schistosoma mansoni hypothetical protein 0.0016 0.0006 0.0007
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Trypanosoma cruzi proteasome regulatory non-ATPase subunit 11, putative 0.0018 0.0031 0.0284
Echinococcus multilocularis neuropeptide FF receptor 2 0.005 0.0391 0.0485
Loa Loa (eye worm) PHD-finger family protein 0.0021 0.0063 0.0114
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0163 0.1697 0.3848
Echinococcus multilocularis solute carrier family 22 0.0029 0.0157 0.019
Entamoeba histolytica hypothetical protein 0.0046 0.0355 0.0852
Brugia malayi Dopamine receptor protein 2 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.005 0.0391 0.0492
Schistosoma mansoni serine/threonine protein kinase 0.0064 0.0554 0.0697
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.0391 0.0485
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0391 0.0485
Onchocerca volvulus Poor gastrulation protein homolog 0.0027 0.0126 0.0154
Echinococcus granulosus histone lysine methyltransferase setb 0.0018 0.0028 0.0028
Echinococcus granulosus fmrfamide receptor 0.005 0.0391 0.0485
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0564 0.512
Echinococcus multilocularis solute carrier family 22 0.0029 0.0157 0.019
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Brugia malayi 26S proteasome regulatory subunit rpn11 0.0024 0.0098 0.0183
Brugia malayi Serotonin receptor 0.005 0.0391 0.0766
Echinococcus granulosus fetal alzheimer antigen falz 0.0025 0.0105 0.0125
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni microtubule-associated protein tau 0.0706 0.7953 1
Schistosoma mansoni opsin-like receptor 0.005 0.0391 0.0492
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Onchocerca volvulus 0.0029 0.0157 0.0216
Onchocerca volvulus 0.005 0.0391 0.0686
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0564 0.1466
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Brugia malayi Bromodomain containing protein 0.0034 0.0216 0.0418
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.005 0.0391 0.0492
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0355 0.0753
Schistosoma mansoni protein kinase 0.0064 0.0554 0.0697
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.005 0.0391 0.0485
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0039 0.0274 0.0592
Echinococcus granulosus g protein coupled receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0047 0.0428
Echinococcus multilocularis Protein lozenge 0.0057 0.0475 0.059
Schistosoma mansoni hypothetical protein 0.0021 0.0063 0.0079
Leishmania major DNA polymerase eta, putative 0.002 0.0047 0.0428
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Trypanosoma cruzi hexose transporter 0.0065 0.0564 0.512
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0047 0.0044
Mycobacterium ulcerans epoxide hydrolase EphA 0.0395 0.4366 1
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0188 0.0143
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0037 0.0243 0.0299
Echinococcus multilocularis calcium dependent protein kinase 0.006 0.0509 0.0633
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0099 0.09
Echinococcus granulosus metabotropic glutamate receptor 2 0.0137 0.1399 0.1753
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0042 0.0303 0.0591
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi F/Y-rich N-terminus family protein 0.0021 0.0066 0.012
Loa Loa (eye worm) hypothetical protein 0.0032 0.0188 0.0362
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0099 0.0163
Echinococcus granulosus neuropeptide s receptor 0.005 0.0391 0.0485
Brugia malayi Sugar transporter family protein 0.0208 0.2218 0.4395
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.005 0.0391 0.0492
Loa Loa (eye worm) neuropeptide F receptor 0.005 0.0391 0.0766
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0166 0.4204
Schistosoma mansoni myosin xvIII 0.005 0.0391 0.0492
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Brugia malayi Hypothetical 35.8 kDa protein F37A4.5 in chromosome III 0.0024 0.0098 0.0183
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0021 0.0019
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.005 0.0391 0.0485
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus neuropeptide Y receptor 0.005 0.0391 0.0485
Schistosoma mansoni glucose transport protein 0.0208 0.2218 0.2789
Plasmodium falciparum phd finger protein, putative 0.0032 0.0188 0.016
Brugia malayi Serotonin receptor 0.005 0.0391 0.0766
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0024 0.0095 0.0154
Entamoeba histolytica hypothetical protein 0.0024 0.0095 0.0133
Echinococcus multilocularis lysyl tRNA synthetase 0.0046 0.0355 0.044
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Leishmania major hypothetical protein, conserved 0.0029 0.0157 0.1426
Onchocerca volvulus 0.0029 0.0157 0.0216
Entamoeba histolytica transcription factor BTF3, putative 0.004 0.028 0.0643
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0185
Brugia malayi hypothetical protein 0.0125 0.1264 0.2499
Brugia malayi lysyl-tRNA synthetase 0.0046 0.0355 0.0694
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Plasmodium vivax 26S proteasome regulatory subunit RPN11, putative 0.0024 0.0098 0.0069
Giardia lamblia DINP protein human, muc B family 0.002 0.0047 0.0044
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0064 0.0555 0.0528
Onchocerca volvulus Huntingtin homolog 0.0125 0.1264 0.2434
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0391 0.0492
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0334 0.3663 1
Onchocerca volvulus 0.0029 0.0157 0.0216
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Brugia malayi Tachykinin-like peptides receptor 99D 0.005 0.0391 0.0766
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0039 0.0274 0.1118
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0188 0.023
Loa Loa (eye worm) hypothetical protein 0.0045 0.0342 0.0667
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0024 0.0098 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.004 0.028 0.0684
Schistosoma mansoni hypothetical protein 0.0035 0.0221 0.0278
Onchocerca volvulus 0.005 0.0391 0.0686
Loa Loa (eye worm) hypothetical protein 0.0051 0.0407 0.0798
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium ulcerans integral membrane transport protein 0.0029 0.0157 0.0296
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.005 0.0391 0.0492
Plasmodium falciparum calcium-dependent protein kinase 2 0.0064 0.0555 0.0528
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0046 0.0355 0.3226
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0188 0.0236
Loa Loa (eye worm) hypothetical protein 0.0085 0.08 0.1577
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0337 0.3696 0.3678
Trypanosoma cruzi sugar transporter, putative 0.0029 0.0157 0.1426
Brugia malayi jmjC domain containing protein 0.0105 0.1026 0.2027
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0047 0.0044
Plasmodium vivax hexose transporter 0.0208 0.2218 0.2196
Echinococcus multilocularis serotonin receptor 0.005 0.0391 0.0485
Echinococcus multilocularis neuropeptide receptor 0.005 0.0391 0.0485
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Schistosoma mansoni cpg binding protein 0.0033 0.02 0.0251
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0407 0.0798
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Echinococcus granulosus transcription factor btf3 0.004 0.028 0.0345
Brugia malayi larval opioid receptor 0.005 0.0391 0.0766
Brugia malayi putative neuropeptide receptor NPR1 0.005 0.0391 0.0766
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Echinococcus multilocularis lysine specific demethylase 5A 0.0039 0.0265 0.0327
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Echinococcus multilocularis neuropeptide Y receptor 0.005 0.0391 0.0485
Onchocerca volvulus 0.005 0.0391 0.0686
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.005 0.0391 0.0766
Schistosoma mansoni DNA polymerase eta 0.002 0.0047 0.0059
Loa Loa (eye worm) hypothetical protein 0.0018 0.0028 0.0045
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0111 0.1101 0.2861
Loa Loa (eye worm) follicle stimulating hormone receptor 0.005 0.0391 0.0766
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.058 0.1141
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0046 0.0355 0.3226
Brugia malayi hypothetical protein 0.0029 0.0157 0.0301
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0063 0.0543 0.0676
Echinococcus granulosus dna polymerase kappa 0.002 0.0047 0.0052
Loa Loa (eye worm) hypothetical protein 0.0024 0.0099 0.0186
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Plasmodium falciparum calcium-dependent protein kinase 4 0.0064 0.0555 0.0528
Brugia malayi G protein-coupled receptor 0.005 0.0391 0.0766
Toxoplasma gondii NAC domain-containing protein 0.004 0.028 0.0283
Plasmodium falciparum calcium-dependent protein kinase 5 0.0064 0.0555 0.0528
Loa Loa (eye worm) hypothetical protein 0.002 0.0049 0.0086
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0188 0.0143
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni hypothetical protein 0.0032 0.0188 0.0236
Echinococcus granulosus thyrotropin releasing hormone receptor 0.005 0.0391 0.0485
Plasmodium falciparum 26S proteasome regulatory subunit RPN11, putative 0.0024 0.0098 0.0069
Schistosoma mansoni hypothetical protein 0.005 0.0391 0.0492
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0028 0.0026
Echinococcus multilocularis 26S proteasome regulatory subunit N11 0.0018 0.0031 0.0032
Schistosoma mansoni amine GPCR 0.005 0.0391 0.0492
Echinococcus multilocularis orexin receptor type 2 0.005 0.0391 0.0485
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Onchocerca volvulus 0.005 0.0391 0.0686
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Trichomonas vaginalis myo-inositol transporter, putative 0.0029 0.0157 0.0346
Onchocerca volvulus 0.005 0.0391 0.0686
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0166 0.0138
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Entamoeba histolytica phosphofructokinase, putative 0.0111 0.1101 0.2914
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus multilocularis dro:myosuppressin receptor 0.005 0.0391 0.0485
Mycobacterium ulcerans 6-phosphofructokinase 0.0111 0.1101 0.2472
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0166 0.037
Echinococcus multilocularis g protein coupled receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi 6-phosphofructokinase 0.0111 0.1101 0.2175
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0047 0.0043
Schistosoma mansoni biogenic amine receptor 0.005 0.0391 0.0492
Plasmodium falciparum hexose transporter 0.0208 0.2218 0.2196
Loa Loa (eye worm) hypothetical protein 0.0062 0.0539 0.106
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0047 0.0052
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0166 0.037
Loa Loa (eye worm) proteasome 26S subunit 0.0018 0.0031 0.0051
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0029 0.0157 0.0322
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Loa Loa (eye worm) glutamate receptor 0.0064 0.0561 0.1104
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0029 0.0157 0.0296
Brugia malayi Dopamine receptor 0.005 0.0391 0.0766
Brugia malayi Cam kinase protein 1 0.0064 0.0554 0.109
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0166 0.0138
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Echinococcus granulosus dna polymerase eta 0.002 0.0047 0.0052
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Trypanosoma brucei unspecified product 0.002 0.0047 0.0428
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0029 0.0157 1
Echinococcus multilocularis g protein coupled receptor 0.005 0.0391 0.0485
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0062 0.0539 0.0678
Loa Loa (eye worm) hypothetical protein 0.0453 0.504 1
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0021 0.0026
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0046 0.0355 0.0753
Trypanosoma cruzi hexose transporter, putative 0.0065 0.0564 0.512
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Echinococcus multilocularis zinc finger protein 0.0022 0.007 0.0081
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Onchocerca volvulus 0.0029 0.0157 0.0216
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0021 0.0019
Echinococcus multilocularis cpg binding protein 0.0033 0.02 0.0245
Brugia malayi sulfakinin receptor protein 0.005 0.0391 0.0766
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Onchocerca volvulus 0.0029 0.0157 0.0216
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0047 0.0428
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0111 0.1101 1
Trichomonas vaginalis conserved hypothetical protein 0.004 0.028 0.0684
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0099 0.0163
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0047 0.0428
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0025 0.0105 0.0132
Entamoeba histolytica 26S proteasome non-ATPase regulatory subunit 14, putative 0.0024 0.0098 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0564 0.1466
Schistosoma mansoni lozenge 0.0057 0.0475 0.0597
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0166 0.037
Echinococcus multilocularis L aminoadipate semialdehyde 0.0085 0.08 0.0999
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0564 0.512
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Schistosoma mansoni peptide (allatostatin)-like receptor 0.005 0.0391 0.0492
Schistosoma mansoni neuropeptide receptor 0.005 0.0391 0.0492
Echinococcus granulosus jumonji domain containing protein 0.0045 0.0332 0.0411
Echinococcus multilocularis g-protein coupled receptor 0.005 0.0391 0.0485
Echinococcus multilocularis matrix metallopeptidase 7 (M10 family) 0.0072 0.0653 0.0815
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Schistosoma mansoni neuropeptide receptor 0.005 0.0391 0.0492
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis General substrate transporter 0.0179 0.1881 0.236
Leishmania major proteasome regulatory non-ATP-ase subunit 11, putative,19S proteasome regulatory subunit, Metallo- peptidase, Clan MP, Family M6 0.0018 0.0031 0.0284
Trypanosoma brucei THT1 - hexose transporter, putative 0.0065 0.0564 0.512
Schistosoma mansoni growth hormone secretagogue receptor 0.005 0.0391 0.0492
Schistosoma mansoni hypothetical protein 0.0028 0.0145 0.0182
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0024 0.0095 0.2046
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0026 0.0115 0.0217
Brugia malayi Bromodomain containing protein 0.0078 0.0723 0.1425
Leishmania major basic transcription factor 3a, putative 0.004 0.028 0.2539
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0099 0.09
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1101 0.2945
Leishmania major myo-inositol/proton symporter (MIT) 0.0029 0.0157 0.1426
Schistosoma mansoni biogenic amine (dopamine) receptor 0.005 0.0391 0.0492
Brugia malayi Sugar transporter family protein 0.0029 0.0157 0.0301
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0157 0.0346
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0188 0.016
Onchocerca volvulus 0.0029 0.0158 0.0219
Echinococcus granulosus tachykinin peptides receptor 99D 0.005 0.0391 0.0485
Trichomonas vaginalis conserved hypothetical protein 0.0065 0.0564 0.1466
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0064 0.0554 0.109
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Onchocerca volvulus 0.005 0.0391 0.0686
Schistosoma mansoni hypothetical protein 0.0208 0.2218 0.2789
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0024 0.0095 0.0154
Schistosoma mansoni neuropeptide receptor 0.005 0.0391 0.0492
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.005 0.0391 0.0485
Schistosoma mansoni glucose transporter 0.0029 0.0157 0.0197
Brugia malayi neuropeptide F receptor 0.005 0.0391 0.0766
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0208 0.2218 0.6021
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0064 0.0554 0.109
Trypanosoma brucei transcription factor BTF3, putative 0.004 0.028 0.2539
Plasmodium vivax CDK-related protein kinase 6, putative 0.0884 1 1
Brugia malayi Bromodomain containing protein 0.0039 0.0271 0.0527
Trypanosoma brucei glucose transporter 1E 0.0065 0.0564 0.512
Schistosoma mansoni biogenic amine receptor 0.005 0.0391 0.0492
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0064 0.0555 0.0528
Brugia malayi Matrixin family protein 0.0048 0.0374 0.0732
Loa Loa (eye worm) hypothetical protein 0.0027 0.0126 0.0239
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0018 0.0028 0.0035
Loa Loa (eye worm) matrixin family protein 0.0044 0.0328 0.0641
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Onchocerca volvulus Putative transporter 0.0029 0.0157 0.0216
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0166 0.0108
Brugia malayi Matrixin family protein 0.002 0.0049 0.0086
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Schistosoma mansoni hypothetical protein 0.005 0.0391 0.0492
Onchocerca volvulus 0.005 0.0391 0.0686
Brugia malayi G-protein coupled receptor 0.005 0.0391 0.0766
Echinococcus multilocularis transcription factor btf3 0.004 0.028 0.0345
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0029 0.0157 0.019
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0047 0.0052
Plasmodium falciparum lysine--tRNA ligase 0.0046 0.0355 0.0328
Echinococcus granulosus neuropeptide receptor 0.005 0.0391 0.0485
Echinococcus granulosus 7tm_1 domain containing protein 0.005 0.0391 0.0485
Onchocerca volvulus 0.005 0.0391 0.0686
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.0208 0.2218 0.2784
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.0391 0.0485
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.005 0.0391 0.0485
Schistosoma mansoni rhodopsin-like orphan GPCR 0.005 0.0391 0.0492
Echinococcus multilocularis somatostatin receptor 0.005 0.0391 0.0485
Treponema pallidum fructose-bisphosphate aldolase 0.0334 0.3663 1
Toxoplasma gondii transporter, major facilitator family protein 0.0029 0.0157 0.0095
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0111 0.1101 0.2492
Loa Loa (eye worm) G-protein coupled receptor 0.005 0.0391 0.0766
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0099 0.0189
Trichomonas vaginalis sugar transporter, putative 0.0065 0.0564 0.1466
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi Matrixin family protein 0.002 0.0049 0.0086
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0407 0.0798
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Brugia malayi hypothetical protein 0.005 0.0391 0.0766
Echinococcus multilocularis dnaJ subfamily B 0.0419 0.464 0.5832
Trichomonas vaginalis conserved hypothetical protein 0.004 0.028 0.0684
Onchocerca volvulus 0.005 0.0391 0.0686
Echinococcus granulosus biogenic amine 5HT receptor 0.005 0.0391 0.0485
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0047 0.0083
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.0391 0.0492
Echinococcus granulosus rhodopsin orphan GPCR 0.005 0.0391 0.0485
Echinococcus multilocularis synaptic vesicle 2 protein 0.0029 0.0157 0.019
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0047 0.0059
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0188 0.023
Echinococcus granulosus neuropeptide receptor 0.005 0.0391 0.0485
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0022 0.0074 0.0105
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi Serotonin/octopamine receptor family protein 7 0.005 0.0391 0.0766
Echinococcus multilocularis serotonin receptor 0.005 0.0391 0.0485
Echinococcus granulosus hypothetical protein 0.005 0.0391 0.0485
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0158 0.0303
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0166 0.4204
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0137 0.1399 0.1753
Loa Loa (eye worm) major facilitator superfamily transporter 0.0029 0.0157 0.0301
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni biogenic amine (5HT) receptor 0.005 0.0391 0.0492
Brugia malayi hypothetical protein 0.0453 0.504 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) sugar transporter 0.0029 0.0157 0.0301
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0085 0.08 0.1005
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Schistosoma mansoni 6-phosphofructokinase 0.0111 0.1101 0.1384
Entamoeba histolytica hypothetical protein 0.004 0.028 0.0643
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0064 0.0554 0.069
Brugia malayi Matrixin family protein 0.002 0.0049 0.0086
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus peptide allatostatin:somatostatin 0.005 0.0391 0.0485
Toxoplasma gondii sugar transporter ST2 0.0029 0.0157 0.0095
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus neuropeptides capa receptor 0.005 0.0391 0.0485
Loa Loa (eye worm) hypothetical protein 0.0042 0.0303 0.0591
Brugia malayi gonadotropin-releasing hormone receptor 2 0.005 0.0391 0.0766
Echinococcus multilocularis fmrfamide receptor 0.005 0.0391 0.0485
Echinococcus granulosus zinc finger protein 0.0022 0.007 0.0081
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.005 0.0391 0.0485
Leishmania major lysyl-tRNA synthetase, putative 0.0046 0.0355 0.3226
Leishmania major glucose transporter, lmgt3 0.0065 0.0564 0.512
Trichomonas vaginalis phosphofructokinase, putative 0.0111 0.1101 0.2945
Onchocerca volvulus Alhambra homolog 0.0032 0.0188 0.0279
Onchocerca volvulus 0.005 0.0391 0.0686
Schistosoma mansoni neuropeptide F-like receptor 0.005 0.0391 0.0492
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0047 0.0083
Schistosoma mansoni neuropeptide receptor 0.005 0.0391 0.0492
Echinococcus multilocularis g protein coupled receptor 0.005 0.0391 0.0485
Echinococcus multilocularis dna polymerase kappa 0.002 0.0047 0.0052
Mycobacterium tuberculosis Probable peptidoglycan hydrolase 0.0024 0.0099 0.0188
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0099 0.0144
Onchocerca volvulus 0.0453 0.504 1
Schistosoma mansoni hypothetical protein 0.0419 0.464 0.5835
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Schistosoma mansoni biogenic amine receptor 0.005 0.0391 0.0492
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0064 0.0555 0.0706
Brugia malayi G protein-coupled receptor F59B2.13 0.005 0.0391 0.0766
Echinococcus multilocularis jumonji domain containing protein 0.0045 0.0332 0.0411
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.005 0.0391 0.0485
Echinococcus granulosus L aminoadipate semialdehyde 0.0085 0.08 0.0999
Echinococcus granulosus solute carrier family 22 0.0029 0.0157 0.019
Mycobacterium leprae PROBABLE HYDROLASE 0.0024 0.0099 0.0023
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0188 0.0362
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Trypanosoma brucei hypothetical protein, conserved 0.0024 0.0095 0.0866
Echinococcus multilocularis neuropeptides capa receptor 0.005 0.0391 0.0485
Schistosoma mansoni hypothetical protein 0.005 0.0391 0.0492
Schistosoma mansoni lysyl-tRNA synthetase 0.0046 0.0355 0.0446
Schistosoma mansoni glucose transport protein 0.0208 0.2218 0.2789
Onchocerca volvulus 0.0028 0.0145 0.0192
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0073 0.0659 0.0866
Brugia malayi follicle stimulating hormone receptor 0.005 0.0391 0.0766
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0029 0.0157 0.0322
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0029 0.0157 0.0129
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.005 0.0391 0.0485
Onchocerca volvulus Matrix metalloproteinase homolog 0.0044 0.0328 0.056
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Brugia malayi Matrixin family protein 0.002 0.0049 0.0086
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0073 0.0659 0.5983
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus calcium dependent protein kinase 0.006 0.0509 0.0633
Echinococcus multilocularis rhodopsin orphan GPCR 0.005 0.0391 0.0485
Loa Loa (eye worm) melatonin receptor type 1A 0.005 0.0391 0.0766
Brugia malayi GnHR receptor homolog 0.005 0.0391 0.0766
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0047 0.0428
Loa Loa (eye worm) glutamate receptor 0.0164 0.1705 0.3375
Echinococcus granulosus solute carrier family 22 0.0029 0.0157 0.019
Echinococcus granulosus neuropeptide FF receptor 2 0.005 0.0391 0.0485
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0025 0.0105 0.0125
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.005 0.0391 0.0766
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0334 0.3663 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0099 0.09
Loa Loa (eye worm) hypothetical protein 0.0035 0.0221 0.0429
Loa Loa (eye worm) hypothetical protein 0.005 0.0391 0.0766
Echinococcus granulosus GPCR family 3 C terminal 0.0027 0.0126 0.0151
Leishmania major glucose transporter, lmgt2 0.0065 0.0564 0.512
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0166 0.0138
Plasmodium vivax lysine--tRNA ligase, putative 0.0046 0.0355 0.0328
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0047 0.0428
Schistosoma mansoni bromodomain containing protein 0.0066 0.0585 0.0735
Trichomonas vaginalis sugar transporter, putative 0.0029 0.0157 0.0346
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0099 0.0024
Loa Loa (eye worm) hypothetical protein 0.0029 0.0157 0.0301
Schistosoma mansoni sugar transporter 0.0029 0.0157 0.0197
Trypanosoma brucei glucose transporter, putative 0.0065 0.0564 0.512
Schistosoma mansoni metabotropic glutamate receptor 0.008 0.0739 0.0929
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0047 0.0428
Brugia malayi hypothetical protein 0.005 0.0391 0.0766

Activities

Activity type Activity value Assay description Source Reference
IC50 (binding) = 1.6 nM Inhibition of human soluble epoxide hydrolase ChEMBL. 21211973
IC50 (binding) = 64 nM Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHET ChEMBL. 21211973
Inhibition (binding) = 11 % Inhibition of human ERG by patch clamp analysis ChEMBL. 21211973

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

If you have references for this compound, please enter them in a user comment (below) or Contact us.