Detailed information for compound 1509687

Basic information

Technical information
  • TDR Targets ID: 1509687
  • Name: 4-phenyl-2,3,4a,5,6,7,8,8a-octahydro-1H-quino lin-4-ol
  • MW: 231.333 | Formula: C15H21NO
  • H donors: 2 H acceptors: 1 LogP: 2.3 Rotable bonds: 1
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC1(CCNC2C1CCCC2)c1ccccc1
  • InChi: 1S/C15H21NO/c17-15(12-6-2-1-3-7-12)10-11-16-14-9-5-4-8-13(14)15/h1-3,6-7,13-14,16-17H,4-5,8-11H2
  • InChiKey: JENIXYWBDVSBMO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • BAS 02785770
  • Quinolin-4-ol, perhydro-4-phenyl-
  • A1893/0079453
  • AG-205/37218001
  • Oprea1_055694
  • 4-Phenyldecahydro-4-quinolinol

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0083 0.0112
Plasmodium falciparum importin beta, putative 0.0028 0.0409 0.7644
Onchocerca volvulus 0.0019 0.0246 0.0602
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0277 0.0353
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0246 0.0346
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.222 0.436
Brugia malayi Voltage-gated calcium channel, T-type, alpha subunit. C. elegans cca-1 ortholog 0.0196 0.3366 0.4347
Schistosoma mansoni calcium channel voltage-dependent p/q type alpha 1a-related 0.0005 0.0004 0.0006
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0246 0.0346
Schistosoma mansoni polycystin 1-related 0.0024 0.0329 0.0469
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.008 0.1313 0.187
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0277 0.5155
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0246 0.0346
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Schistosoma mansoni lipoxygenase 0.01 0.1662 0.2374
Brugia malayi hypothetical protein 0.0024 0.0329 0.042
Brugia malayi hypothetical protein 0.0036 0.0547 0.0702
Brugia malayi Death domain containing protein 0.0017 0.0215 0.0273
Leishmania major importin beta-1 subunit, putative 0.0023 0.0315 0.0402
Loa Loa (eye worm) hypothetical protein 0.0017 0.0215 0.0233
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0246 0.0346
Echinococcus multilocularis kelch ECH associated protein 1 0.0095 0.1583 0.2256
Onchocerca volvulus 0.0028 0.0408 0.1002
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.1892 0.2441
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0035 0.0534 0.1042
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0246 0.0352
Entamoeba histolytica hypothetical protein 0.0012 0.0116 0.022
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0246 0.0346
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.1313 0.1692
Schistosoma mansoni transient receptor potential channel 4 0.0005 0.0004 0.0006
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0445 0.8331
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0445 0.0571
Schistosoma mansoni hypothetical protein 0.0036 0.0547 0.0781
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.1583 0.2042
Schistosoma mansoni hypothetical protein 0.0095 0.1587 0.2267
Schistosoma mansoni hypothetical protein 0.0019 0.0246 0.0352
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0035 0.0534 0.1042
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.1055 0.1501
Schistosoma mansoni amine GPCR 0.0019 0.0246 0.0352
Schistosoma mansoni hypothetical protein 0.0164 0.2802 0.4001
Echinococcus granulosus hypothetical protein 0.0019 0.0246 0.0346
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0534 1
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0246 0.0268
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Echinococcus multilocularis Ankyrin 0.0018 0.0218 0.0305
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0023 0.0309 0.0395
Loa Loa (eye worm) histone methyltransferase 0.001 0.0083 0.0087
Brugia malayi Serotonin receptor 0.0019 0.0246 0.0313
Entamoeba histolytica hypothetical protein 0.0036 0.0547 0.1068
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0547 0.0776
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Brugia malayi Melatonin receptor type 1A 0.0019 0.0246 0.0313
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Echinococcus multilocularis serotonin receptor 0.0019 0.0246 0.0346
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.5087 1
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0246 0.0346
Entamoeba histolytica hypothetical protein 0.0012 0.0116 0.022
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0246 0.0346
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0246 0.0346
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0534 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0246 0.0602
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.1892 0.2441
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0549 0.0705
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0022 0.0036
Brugia malayi hypothetical protein 0.003 0.0445 0.0571
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.222 0.436
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.1313 0.1692
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0246 0.0268
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0246 0.0346
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0547 0.0781
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.5087 1
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0246 0.0268
Echinococcus granulosus transcription factor Dp 1 0.0046 0.0722 0.1026
Trypanosoma cruzi calpain-like cysteine peptidase, putative 0.0113 0.1892 0.2441
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0246 0.0346
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0438 0.062
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0445 0.8331
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0277 0.0353
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0534 0.1042
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0549 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0246 0.0346
Brugia malayi G-protein coupled receptor 0.0019 0.0246 0.0313
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0246 0.0268
Trypanosoma brucei cytochrome P450, putative 0.003 0.0431 0.0552
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni 60S ribosomal protein L21 0.0005 0.0004 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni neuropeptide receptor 0.0019 0.0246 0.0352
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Echinococcus granulosus transient receptor potential cation channel 0.0006 0.0007 0.0004
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0089 0.1475 0.2102
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0246 0.0346
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.2417 0.3447
Brugia malayi Cytochrome P450 family protein 0.0057 0.0916 0.1179
Schistosoma mansoni ryanodine receptor related 0.0005 0.0004 0.0006
Echinococcus multilocularis transient receptor potential cation channel 0.0006 0.0007 0.0004
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0246 0.0352
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0246 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0246 0.0352
Entamoeba histolytica serine/threonine protein kinase, putative 0.0095 0.1583 0.3106
Entamoeba histolytica hypothetical protein 0.0036 0.0547 0.1068
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Brugia malayi Muscleblind-like protein 0.015 0.2556 0.33
Echinococcus multilocularis muscleblind protein 0.015 0.2556 0.3646
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus granulosus Ankyrin 0.0018 0.0218 0.0305
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.008 0.1313 0.1692
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0315 0.0611
Trypanosoma brucei calpain, putative 0.0113 0.1892 0.2441
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0005 0.0004 0.0006
Echinococcus granulosus allatostatin A receptor 0.0019 0.0246 0.0346
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0309 0.0601
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0445 0.7737 1
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0008 0.0052 0.0069
Schistosoma mansoni ran 0.0021 0.0277 0.0396
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Schistosoma mansoni myosin xvIII 0.0019 0.0246 0.0352
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0431 0.0552
Trypanosoma brucei variant surface glycoprotein (VSG), putative 0.0113 0.1892 0.2441
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0246 0.0352
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0022 0.0036
Schistosoma mansoni histamine h1 receptor 0.0019 0.0246 0.0352
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Echinococcus multilocularis transcription factor Dp 1 0.0046 0.0722 0.1026
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0329 0.6128
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0329 0.0464
Echinococcus multilocularis somatostatin receptor 0.0019 0.0246 0.0346
Brugia malayi phosphofructokinase 0.0131 0.222 0.2866
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0035 0.0534 0.0534
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0549 0.0312
Trichomonas vaginalis helicase, putative 0.0006 0.0022 0.0036
Echinococcus granulosus short transient receptor potential channel 6 0.0006 0.0007 0.0004
Echinococcus granulosus fmrfamide receptor 0.0019 0.0246 0.0346
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus granulosus calcium activated potassium channel 0.0006 0.001 0.0008
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0035 0.0534 0.5043
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1892 0.2441
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0022 0.0303 0.0387
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0246 0.0346
Onchocerca volvulus 0.0019 0.0246 0.0602
Brugia malayi Dopamine receptor protein 2 0.0019 0.0246 0.0313
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0245 0.0311
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0005 0.0004 0.0006
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0246 0.0346
Loa Loa (eye worm) hypothetical protein 0.007 0.1141 0.1258
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0005 0.0004 0.0006
Schistosoma mansoni hypothetical protein 0.0019 0.0246 0.0352
Echinococcus multilocularis 0.0019 0.0245 0.0344
Brugia malayi 6-phosphofructokinase 0.0131 0.222 0.2866
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0023 0.0309 0.0601
Loa Loa (eye worm) tumor suppressor 0.0324 0.5606 0.6195
Loa Loa (eye worm) hypothetical protein 0.0152 0.2586 0.2855
Brugia malayi hypothetical protein 0.0027 0.0392 0.0501
Brugia malayi glutaminase DH11.1 0.0269 0.465 0.6008
Echinococcus granulosus importin subunit beta 1 0.0028 0.0409 0.0579
Onchocerca volvulus 0.0024 0.0329 0.0806
Leishmania major hypothetical protein, conserved 0.003 0.0445 0.0571
Mycobacterium ulcerans glutaminase 0.0269 0.465 0.4516
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0445 0.7737 1
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0534 0.1042
Toxoplasma gondii hypothetical protein 0.0005 0.0004 0.0001
Loa Loa (eye worm) hypothetical protein 0.0027 0.0392 0.0429
Schistosoma mansoni amine GPCR 0.0019 0.0246 0.0352
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0144 0.2439 0.2249
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0246 0.0352
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1892 0.2441
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0246 0.0346
Echinococcus granulosus cytochrome P450 2K1 0.0019 0.0245 0.0344
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0246 0.0346
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0246 0.0346
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0315 0.0401
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0482 0.0243
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1892 0.2441
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0246 0.0313
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Onchocerca volvulus 0.0019 0.0246 0.0602
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0309 0.5763
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0014 0.015 0.0208
Brugia malayi Cytochrome P450 family protein 0.003 0.0431 0.0552
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0277 0.26
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1055 0.1506
Schistosoma mansoni hypothetical protein 0.0005 0.0004 0.0006
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0549 0.0705
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0246 0.0352
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0246 0.0346
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0023 0.0309 0.0066
Loa Loa (eye worm) hypothetical protein 0.0227 0.391 0.4319
Trichomonas vaginalis ran, putative 0.0021 0.0277 0.0537
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0246 0.0352
Giardia lamblia Fructose-bisphosphate aldolase 0.0294 0.5087 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0083 0.0112
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0445 0.0571
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.008 0.1313 0.1692
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0246 0.0352
Onchocerca volvulus 0.0019 0.0246 0.0602
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0534 0.1042
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1583 0.3106
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0246 0.0346
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0035 0.0534 1
Schistosoma mansoni biogenic amine receptor 0.0019 0.0246 0.0352
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0246 0.0313
Echinococcus granulosus g protein coupled receptor 0.0019 0.0246 0.0346
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1055 0.083
Brugia malayi Uncoordinated protein 44 0.0017 0.0215 0.0273
Schistosoma mansoni hypothetical protein 0.0027 0.0391 0.0559
Onchocerca volvulus 0.0019 0.0246 0.0602
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0005 0.0004 0.0001
Echinococcus granulosus dnaJ subfamily B 0.0403 0.7003 1
Brugia malayi hypothetical protein 0.002 0.0255 0.0325
Echinococcus granulosus nuclear factor of activated T cells 5 0.0089 0.1475 0.2102
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0277 0.0353
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0246 0.0346
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0246 0.0268
Echinococcus granulosus neuropeptide receptor 0.0019 0.0246 0.0346
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Leishmania major cytochrome p450-like protein 0.0019 0.0245 0.0311
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0438 0.0626
Loa Loa (eye worm) hypothetical protein 0.0024 0.0329 0.0359
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Echinococcus multilocularis calcium activated potassium channel 0.0006 0.001 0.0008
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0246 0.0313
Toxoplasma gondii cytochrome p450 superfamily protein 0.0019 0.0245 0.2293
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0409 0.0524
Echinococcus granulosus death domain containing protein 0.0017 0.0215 0.0302
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0408 0.0577
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0534 0.5
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0131 0.222 0.2025
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0246 0.0313
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0246 0.0346
Schistosoma mansoni hypothetical protein 0.0019 0.0246 0.0352
Brugia malayi hypothetical protein 0.007 0.1141 0.1471
Echinococcus multilocularis muscleblind protein 1 0.015 0.2556 0.3646
Loa Loa (eye worm) hypothetical protein 0.0028 0.0409 0.0448
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.1055 0.083
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.008 0.1313 0.187
Echinococcus granulosus g protein coupled receptor 0.0019 0.0246 0.0346
Schistosoma mansoni ap endonuclease 0.0023 0.0309 0.0442
Onchocerca volvulus 0.0019 0.0246 0.0602
Echinococcus granulosus geminin 0.0164 0.2802 0.3997
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0246 0.0346
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Schistosoma mansoni inositol 145-trisphosphate receptor 0.0005 0.0004 0.0006
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.5087 1
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0409 0.0524
Trypanosoma cruzi cytochrome P450, putative 0.003 0.0431 0.0552
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Onchocerca volvulus 0.0019 0.0246 0.0602
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0246 0.0346
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.008 0.1313 0.2575
Onchocerca volvulus 0.0019 0.0246 0.0602
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.222 0.317
Echinococcus granulosus 6 phosphofructokinase 0.0131 0.222 0.3167
Toxoplasma gondii transporter, cation channel family protein 0.0005 0.0004 0.0001
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0014 0.015 0.0208
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0246 0.0346
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.1055 0.1359
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0445 0.0571
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0246 0.0268
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0409 0.3855
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0019 0.0245 0.0311
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0277 0.039
Onchocerca volvulus 0.0019 0.0246 0.0602
Loa Loa (eye worm) CYP4Cod1 0.003 0.0431 0.0472
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Echinococcus multilocularis serotonin receptor 0.0019 0.0246 0.0346
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0549 0.1073
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0019 0.0245 0.0311
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0246 0.0346
Schistosoma mansoni importin-beta 2 0.0005 0.0004 0.0006
Schistosoma mansoni tsg101-related 0.0058 0.0935 0.1336
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0549 0.1073
Brugia malayi Pre-SET motif family protein 0.003 0.0438 0.0561
Brugia malayi exodeoxyribonuclease III family protein 0.0023 0.0309 0.0395
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0005 0.0004 0.0006
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0019 0.0245 0.0311
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0329 0.0464
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0246 0.0352
Schistosoma mansoni transient receptor potential channel 0.0006 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0329 0.0464
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0431 0.0472
Echinococcus granulosus RUN 0.0024 0.0329 0.0464
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.222 0.436
Loa Loa (eye worm) hypothetical protein 0.0024 0.0329 0.0359
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0246 0.0313
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0005 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.015 0.2556 0.2821
Onchocerca volvulus 0.0019 0.0246 0.0602
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0023 0.0309 0.0395
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0246 0.0346
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0438 0.062
Schistosoma mansoni glutaminase 0.0269 0.465 0.664
Echinococcus granulosus muscleblind protein 0.015 0.2556 0.3646
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0095 0.1583 0.2256
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0246 0.0346
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0409 0.0579
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0022 0.0036
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.222 0.436
Echinococcus granulosus mixed lineage leukemia protein mll 0.0008 0.0052 0.0069
Trypanosoma cruzi polo-like protein kinase, putative 0.0095 0.1583 0.2042
Schistosoma mansoni cpg binding protein 0.003 0.0436 0.0623
Onchocerca volvulus 0.0234 0.4031 1
Schistosoma mansoni neuropeptide receptor 0.0019 0.0246 0.0352
Trypanosoma brucei calpain-like protein, putative 0.0113 0.1892 0.2441
Trypanosoma brucei polo-like protein kinase 0.0095 0.1583 0.2042
Schistosoma mansoni vesicular amine transporter 0.0005 0.0004 0.0006
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0277 0.0302
Echinococcus multilocularis sex peptide receptor 0.0019 0.0246 0.0346
Echinococcus granulosus kelch ECH associated protein 1 0.0095 0.1583 0.2256
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0116 0.0144
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0006 0.0012 0.0078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trypanosoma brucei cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1892 0.2441
Entamoeba histolytica hypothetical protein 0.0036 0.0547 0.1068
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0022 0.0036
Treponema pallidum fructose-bisphosphate aldolase 0.0294 0.5087 1
Schistosoma mansoni rab6-interacting 0.0024 0.0329 0.0469
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0246 0.0346
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.1055 0.1501
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0246 0.0346
Schistosoma mansoni kinase 0.0048 0.076 0.1085
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0246 0.0352
Schistosoma mansoni adenoreceptor 0.0019 0.0246 0.0352
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0246 0.0268
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.0215 0.0273
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0008 0.0052 0.0069
Schistosoma mansoni transient receptor potential channel 0.0005 0.0004 0.0006
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Entamoeba histolytica hypothetical protein 0.0023 0.0315 0.0611
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.0215 0.0302
Brugia malayi larval opioid receptor 0.0019 0.0246 0.0313
Trypanosoma cruzi calpain cysteine peptidase, putative 0.0113 0.1892 0.2441
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Echinococcus granulosus netrin receptor unc 5 0.0017 0.0215 0.0302
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0005 0.0004 0.0006
Schistosoma mansoni cpg binding protein 0.003 0.0436 0.0623
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0246 0.0346
Toxoplasma gondii phosphofructokinase PFKII 0.0035 0.0534 0.5043
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0023 0.0309 0.0338
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0246 0.0352
Toxoplasma gondii exonuclease III APE 0.0023 0.0309 0.2906
Loa Loa (eye worm) cytochrome P450 family protein 0.0057 0.0916 0.1008
Toxoplasma gondii transporter, cation channel family protein 0.0005 0.0004 0.0001
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Schistosoma mansoni tsg101-related 0.0058 0.0935 0.1336
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Loa Loa (eye worm) glutaminase 2 0.0269 0.465 0.5137
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0246 0.0346
Brugia malayi sulfakinin receptor protein 0.0019 0.0246 0.0313
Brugia malayi Importin beta-1 subunit 0.0028 0.0409 0.0524
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0095 0.1583 0.2256
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0549 0.1073
Schistosoma mansoni biogenic amine receptor 0.0019 0.0246 0.0352
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0277 0.039
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0246 0.0346
Entamoeba histolytica Ran family GTPase 0.0021 0.0277 0.0537
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0246 0.0352
Schistosoma mansoni inositol monophosphatase 0.0036 0.0549 0.0784
Echinococcus granulosus somatostatin receptor 0.0019 0.0246 0.0346
Schistosoma mansoni high voltage-activated calcium channel Cav2A 0.0005 0.0004 0.0006
Brugia malayi CXXC zinc finger family protein 0.0028 0.0408 0.0522
Trichomonas vaginalis hypothetical protein 0.0034 0.051 0.0995
Schistosoma mansoni hypothetical protein 0.0403 0.7003 1
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0246 0.0346
Trichomonas vaginalis ap endonuclease, putative 0.0023 0.0309 0.0601
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0017 0.0215 0.0233
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.5087 1
Schistosoma mansoni hypothetical protein 0.0014 0.015 0.0214
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0246 0.0346
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0534 0.1042
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0095 0.1583 0.2042
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0006 0.0022 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0549 0.519
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0246 0.0346
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0445 0.8331
Echinococcus granulosus protein quaking 0.0027 0.0391 0.0554
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0005 0.0004 0.0006
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0246 0.0313
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.5087 1
Schistosoma mansoni opsin-like receptor 0.0019 0.0246 0.0352
Schistosoma mansoni hypothetical protein 0.0027 0.0391 0.0559
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1583 0.3106
Loa Loa (eye worm) hypothetical protein 0.003 0.0445 0.0488
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0023 0.0309 0.0436
Brugia malayi neuropeptide F receptor 0.0019 0.0246 0.0313
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0438 0.0626
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0005 0.0004 0.0006
Brugia malayi AKH receptor 0.0019 0.0246 0.0313
Echinococcus granulosus tumor susceptibility gene 101 protein 0.007 0.1141 0.1625
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0549 0.0779
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.222 0.245
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0246 0.0352
Loa Loa (eye worm) hypothetical protein 0.0519 0.9048 1
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0246 0.0268
Schistosoma mansoni neuropeptide receptor 0.0019 0.0246 0.0352
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Echinococcus multilocularis geminin 0.0164 0.2802 0.3997
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0246 0.0313
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0246 0.0346
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0329 0.0464
Brugia malayi Inositol-1 0.0036 0.0549 0.0705
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0329 0.0464
Plasmodium vivax 6-phosphofructokinase, putative 0.0035 0.0534 1
Brugia malayi Pre-SET motif family protein 0.0206 0.353 0.4559
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.003 0.0431 0.0191
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0246 0.0346
Echinococcus multilocularis kelch ECH associated protein 1 0.0095 0.1583 0.2256
Leishmania major hypothetical protein, conserved 0.0022 0.0303 0.0387
Brugia malayi RNA, U transporter 1 0.0081 0.133 0.1714
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1583 0.3106
Trichomonas vaginalis set domain proteins, putative 0.0234 0.4028 0.7917
Echinococcus multilocularis dnaJ subfamily B 0.0403 0.7003 1
Brugia malayi follicle stimulating hormone receptor 0.0297 0.5136 0.6637
Echinococcus multilocularis 6 phosphofructokinase 0.0131 0.222 0.3167
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1892 0.2441
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Onchocerca volvulus 0.0019 0.0246 0.0602
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0738 0.1444
Brugia malayi ORL1-like opioid receptor 0.0019 0.0246 0.0313
Loa Loa (eye worm) 6-phosphofructokinase 0.0131 0.222 0.245
Brugia malayi 6-phosphofructokinase 0.0131 0.222 0.2866
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0206 0.353 0.3898
Loa Loa (eye worm) hypothetical protein 0.003 0.0438 0.048
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0534 0.1042
Loa Loa (eye worm) hypothetical protein 0.0006 0.0007 0.0003
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.2417 0.3447
Schistosoma mansoni ap endonuclease 0.0023 0.0309 0.0442
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.1055 1
Onchocerca volvulus 0.0019 0.0246 0.0602
Brugia malayi Dopamine receptor 0.0019 0.0246 0.0313
Echinococcus multilocularis cpg binding protein 0.003 0.0436 0.0617
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0872 0.8263
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0246 0.0346
Entamoeba histolytica hypothetical protein 0.0036 0.0547 0.1068
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1583 0.3106
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0095 0.1583 0.1746
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1892 0.2441
Echinococcus granulosus neuropeptide receptor 0.0019 0.0246 0.0346
Schistosoma mansoni two-pore calcium channel 0.0005 0.0004 0.0006
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0315 0.0611
Schistosoma mansoni loxhd1 0.0024 0.0329 0.0469
Schistosoma mansoni neuropeptide receptor 0.0019 0.0246 0.0352
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0277 0.0353
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1583 0.3106
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0297 0.5136 0.5675
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0408 0.0446
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Onchocerca volvulus 0.0019 0.0246 0.0602
Schistosoma mansoni hypothetical protein 0.0019 0.0246 0.0352
Echinococcus multilocularis snurportin 1 0.0303 0.5241 0.7483
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0438 0.4132
Schistosoma mansoni hypothetical protein 0.0164 0.2802 0.4001
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Brugia malayi neuropeptide F receptor 0.0019 0.0246 0.0313
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0329 0.0464
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0246 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0246 0.0346
Schistosoma mansoni hypothetical protein 0.0303 0.5241 0.7485
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0438 0.062
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0482 0.0243
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0549 0.0705
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0445 0.4201
Echinococcus multilocularis protein quaking 0.0027 0.0391 0.0554
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0246 0.0346
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0131 0.222 0.2025
Loa Loa (eye worm) hypothetical protein 0.0018 0.0218 0.0236
Loa Loa (eye worm) hypothetical protein 0.0519 0.9048 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Onchocerca volvulus 0.0152 0.2586 0.6413
Schistosoma mansoni netrin receptor unc5 0.0017 0.0215 0.0307
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0022 0.0036
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0246 0.0313
Schistosoma mansoni amine GPCR 0.0019 0.0246 0.0352
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0246 0.0346
Brugia malayi Serotonin receptor 0.0019 0.0246 0.0313
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.222 0.2866
Trypanosoma cruzi cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1892 0.2441
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1583 0.3106
Trypanosoma brucei calpain-like cysteine peptidase, putative 0.0113 0.1892 0.2441
Onchocerca volvulus Serine\/threonine kinase homolog 0.0095 0.1583 0.3921
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0035 0.0534 0.5
Brugia malayi Protein kinase domain containing protein 0.0018 0.0221 0.028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0023 0.0309 0.0395
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Trichomonas vaginalis conserved hypothetical protein 0.0191 0.3271 0.6428
Loa Loa (eye worm) glutaminase 0.0269 0.465 0.5137
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Brugia malayi putative neuropeptide receptor 0.0019 0.0246 0.0313
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni hypothetical protein 0.0019 0.0245 0.035
Leishmania major GTP-binding protein, putative 0.0021 0.0277 0.0353
Brugia malayi G protein-coupled receptor 0.0019 0.0246 0.0313
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0012 0.0116 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni voltage-dependent calcium channel 0.0005 0.0004 0.0006
Brugia malayi Temporarily assigned gene name protein 44 0.0027 0.0392 0.0501
Echinococcus granulosus hypothetical protein 0.0027 0.0391 0.0554
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0246 0.0346
Schistosoma mansoni calcium-activated potassium channel 0.0005 0.0004 0.0006
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0005 0.0004 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0246 0.0346
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0246 0.0346
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0246 0.0352
Loa Loa (eye worm) hypothetical protein 0.0011 0.0096 0.0101
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0035 0.0534 0.047
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0246 0.0352
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0329 0.0359
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0246 0.0346
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0438 0.0626
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0277 0.5155
Brugia malayi GnHR receptor homolog 0.0019 0.0246 0.0313
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0246 0.0352
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0023 0.0309 0.0436
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0246 0.0352
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0246 0.0346
Schistosoma mansoni rab6-interacting 0.0024 0.0329 0.0469
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1892 0.2441
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0144 0.2439 0.2249
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0246 0.0268
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Brugia malayi Dopamine receptor protein 1 0.0019 0.0246 0.0313
Loa Loa (eye worm) inositol-1 0.0036 0.0549 0.0603
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.5087 1
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0008 0.0052 0.0069
Schistosoma mansoni opsin-like receptor 0.0019 0.0246 0.0352
Trichomonas vaginalis CAMK family protein kinase 0.0095 0.1583 0.3106
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.5087 1
Brugia malayi hypothetical protein 0.0024 0.0329 0.042
Onchocerca volvulus 0.0019 0.0246 0.0602
Mycobacterium ulcerans 6-phosphofructokinase 0.0131 0.222 0.2025
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0081 0.0099
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni transient receptor potential channel 0.0005 0.0004 0.0006
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0246 0.0346
Entamoeba histolytica hypothetical protein 0.0012 0.0116 0.022
Leishmania major cytochrome p450-like protein 0.0019 0.0245 0.0311
Trichomonas vaginalis glutaminase, putative 0.0269 0.465 0.914
Schistosoma mansoni hypothetical protein 0.0017 0.0215 0.0307
Schistosoma mansoni cytochrome P450 0.0019 0.0245 0.035
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0246 0.0346
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0005 0.0004 0.0006
Echinococcus granulosus kelch ECH associated protein 1 like 0.0095 0.1583 0.2256
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0023 0.0309 0.0067
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0144 0.2439 0.2249
Echinococcus multilocularis Kelch repeat type 1 0.0095 0.1587 0.2262
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0005 0.0004 0.0006
Brugia malayi cytochrome P450 0.0019 0.0245 0.0311
Trypanosoma brucei C-8 sterol isomerase, putative 0.0445 0.7737 1
Onchocerca volvulus 0.003 0.0438 0.1078
Onchocerca volvulus 0.0019 0.0246 0.0602
Loa Loa (eye worm) hypothetical protein 0.0445 0.7737 0.855
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0246 0.0346
Schistosoma mansoni amine GPCR 0.0019 0.0246 0.0352
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.008 0.1313 0.1692
Plasmodium vivax SET domain protein, putative 0.003 0.0438 0.8194
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0005 0.0004 0.0001
Brugia malayi G-protein coupled receptor 0.0019 0.0246 0.0313
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0549 0.0705
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0022 0.0303 0.0387
Trichomonas vaginalis phosphofructokinase, putative 0.0035 0.0534 0.1042
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0985 0.1407
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Leishmania major calpain-like cysteine peptidase, putative,cysteine peptidase, Clan CA, family C2, putative 0.0113 0.1892 0.2441
Loa Loa (eye worm) cytochrome P450 0.0019 0.0245 0.0266
Onchocerca volvulus 0.0019 0.0246 0.0602
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Toxoplasma gondii hypothetical protein 0.0005 0.0004 0.0001
Brugia malayi hypothetical protein 0.0152 0.2586 0.3339
Schistosoma mansoni biogenic amine receptor 0.0019 0.0246 0.0352
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0294 0.5087 1
Schistosoma mansoni importin beta-1 0.0028 0.0409 0.0584
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0246 0.0346
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0246 0.0346
Brugia malayi olfactory channel protein osm-9 0.0006 0.0007 0.0004
Brugia malayi Cytochrome P450 family protein 0.0019 0.0245 0.0311
Toxoplasma gondii transporter, cation channel family protein 0.0005 0.0004 0.0001
Onchocerca volvulus Netrin receptor homolog 0.0017 0.0215 0.0524
Schistosoma mansoni hypothetical protein 0.0024 0.0329 0.0469
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.0215 0.0307
Echinococcus multilocularis RUN 0.0024 0.0329 0.0464
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.5087 1
Loa Loa (eye worm) phosphofructokinase 0.0131 0.222 0.245
Schistosoma mansoni high voltage-activated calcium channel Cav1 0.0005 0.0004 0.0006
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0246 0.0346
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni opsin-like receptor 0.0019 0.0246 0.0352
Echinococcus multilocularis netrin receptor unc 5 0.0017 0.0215 0.0302
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1055 0.083
Echinococcus granulosus sex peptide receptor 0.0019 0.0246 0.0346
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0116 0.022
Echinococcus multilocularis short transient receptor potential channel 6 0.0006 0.0007 0.0004
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.5241 0.5791
Schistosoma mansoni amine GPCR 0.0019 0.0246 0.0352
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0246 0.0346
Brugia malayi hypothetical protein 0.0019 0.0246 0.0313
Toxoplasma gondii 6-phosphofructokinase 0.0035 0.0534 0.5043
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0246 0.0346
Schistosoma mansoni serine/threonine protein kinase 0.0095 0.1583 0.226
Echinococcus multilocularis transient receptor potential cation channel 0.0006 0.0007 0.0004
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.0215 0.0302
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0315 0.0611
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0005 0.0004 0.0006
Giardia lamblia Kinase, PLK 0.0095 0.1583 0.2715
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0023 0.0309 0.0395
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0022 0.0036
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Trichomonas vaginalis CAMK family protein kinase 0.0047 0.0738 0.1444
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.222 0.436
Trypanosoma brucei hypothetical protein 0.0113 0.1892 0.2441
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0246 0.0346
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0018 0.0218 0.0311
Plasmodium vivax importin-beta 2, putative 0.0028 0.0409 0.7644
Plasmodium falciparum LCCL domain-containing protein 0.0024 0.0329 0.6128
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0547 0.0776
Schistosoma mansoni voltage-gated cation channel 0.0005 0.0004 0.0006
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0549 0.1073
Echinococcus granulosus orexin receptor type 2 0.0019 0.0246 0.0346
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1055 0.1506
Brugia malayi Cytochrome P450 family protein 0.003 0.0431 0.0552
Loa Loa (eye worm) cytochrome P450 family protein 0.003 0.0431 0.0472
Entamoeba histolytica hypothetical protein 0.0012 0.0116 0.022
Schistosoma mansoni voltage-gated ion channel 0.0005 0.0004 0.0006
Schistosoma mansoni transient receptor potential cation channel subfamily m member 0.0005 0.0004 0.0006
Leishmania major ATP-dependent phosphofructokinase 0.0131 0.222 0.2866
Loa Loa (eye worm) hypothetical protein 0.0196 0.3366 0.3717
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0549 0.0779
Brugia malayi RE15519p 0.0019 0.0246 0.0313
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0023 0.0309 0.0066
Echinococcus granulosus kelch ECH associated protein 1 like 0.0095 0.1583 0.2256
Brugia malayi Doublecortin family protein 0.0024 0.0329 0.042
Brugia malayi serine/threonine-protein kinase plk-2 0.0095 0.1583 0.2042
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0438 0.0626
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0246 0.0346
Schistosoma mansoni inositol monophosphatase 0.0036 0.0549 0.0784
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0006 0.0022 0.0036
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.007 0.1141 0.1625
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0131 0.222 0.4
Brugia malayi tumor suppressor. 0.0324 0.5606 0.7245
Schistosoma mansoni ran 0.0021 0.0277 0.0396
Schistosoma mansoni cpg binding protein 0.0028 0.0408 0.0582
Entamoeba histolytica phosphofructokinase, putative 0.0131 0.222 0.436
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Onchocerca volvulus 0.0024 0.0329 0.0806
Schistosoma mansoni 6-phosphofructokinase 0.0131 0.222 0.317
Trichomonas vaginalis phosphofructokinase, putative 0.0131 0.222 0.436
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0294 0.5087 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1055 0.083
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0246 0.0346
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0023 0.0309 0.5763
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0008 0.0052 0.0075
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0246 0.0352
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0246 0.0268
Schistosoma mansoni tsg101-related 0.0048 0.0747 0.1067
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Echinococcus granulosus serotonin receptor 0.0019 0.0246 0.0346
Onchocerca volvulus 0.0019 0.0246 0.0602
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0246 0.0352
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0048 0.0747 0.1463
Schistosoma mansoni lipoxygenase 0.0142 0.2417 0.3451
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.008 0.1313 0.1875
Loa Loa (eye worm) hypothetical protein 0.015 0.2556 0.2821
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0246 0.0352
Trypanosoma brucei ULK family serine/threonine-protein kinase, putative 0.0006 0.0009 0.0007
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0246 0.0346
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0246 0.0346
Echinococcus granulosus snurportin 1 0.0303 0.5241 0.7483
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.008 0.1313 0.1447
Trypanosoma cruzi hypothetical protein, conserved 0.0012 0.0116 0.0144
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Trichomonas vaginalis conserved hypothetical protein 0.0012 0.0116 0.022
Schistosoma mansoni voltage-gated potassium channel 0.0005 0.0004 0.0006
Leishmania major cytochrome p450-like protein 0.003 0.0431 0.0552
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0246 0.0602
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0246 0.0352
Echinococcus granulosus cpg binding protein 0.003 0.0436 0.0617
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0131 0.222 0.2866
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0019 0.0245 0.0311
Leishmania major C-8 sterol isomerase-like protein 0.0445 0.7737 1
Trichomonas vaginalis conserved hypothetical protein 0.0006 0.0022 0.0036
Loa Loa (eye worm) hypothetical protein 0.0019 0.0246 0.0268
Echinococcus granulosus g protein coupled receptor 0.0019 0.0246 0.0346

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.