Detailed information for compound 1544839

Basic information

Technical information
  • TDR Targets ID: 1544839
  • Name: N-cyclohexyl-2-[[4-ethyl-5-[[[2-(4-methoxyphe nyl)acetyl]amino]methyl]-1,2,4-triazol-3-yl]s ulfanyl]acetamide
  • MW: 445.578 | Formula: C22H31N5O3S
  • H donors: 2 H acceptors: 4 LogP: 2.44 Rotable bonds: 12
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)CC(=O)NCc1nnc(n1CC)SCC(=O)NC1CCCCC1
  • InChi: 1S/C22H31N5O3S/c1-3-27-19(14-23-20(28)13-16-9-11-18(30-2)12-10-16)25-26-22(27)31-15-21(29)24-17-7-5-4-6-8-17/h9-12,17H,3-8,13-15H2,1-2H3,(H,23,28)(H,24,29)
  • InChiKey: JVEKCFRVURUFBQ-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • N-cyclohexyl-2-[[4-ethyl-5-[[[2-(4-methoxyphenyl)-1-oxoethyl]amino]methyl]-1,2,4-triazol-3-yl]thio]acetamide
  • N-cyclohexyl-2-[[4-ethyl-5-[[[2-(4-methoxyphenyl)acetyl]amino]methyl]-1,2,4-triazol-3-yl]thio]acetamide
  • N-cyclohexyl-2-[[4-ethyl-5-[[2-(4-methoxyphenyl)ethanoylamino]methyl]-1,2,4-triazol-3-yl]sulfanyl]ethanamide
  • N-cyclohexyl-2-{[4-ethyl-5-({[(4-methoxyphenyl)acetyl]amino}methyl)-4H-1,2,4-triazol-3-yl]thio}acetamide
  • SMR000143246
  • STK115521
  • AN-698/41761679
  • ZINC00686699
  • MLS000594127

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0011 0.0018
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0067 0.0067
Brugia malayi Thioredoxin reductase 0.0142 0.1435 0.3001
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.0231 0.0231
Onchocerca volvulus 0.0034 0.024 0.0501
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0346 0.109
Leishmania major gamma-glutamylcysteine synthetase, putative 0.0443 0.478 1
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0142 0.1435 0.9713
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0015 0.002 0.002
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0266 0.0551
Loa Loa (eye worm) hypothetical protein 0.0015 0.002 0.0042
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0037 0.0265 0.1778
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0049 0.0404 0.2723
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0029
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0049 0.0404 0.0841
Echinococcus granulosus 6 phosphofructokinase 0.0122 0.1217 0.2546
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0016 0.0037 0.0078
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0049 0.0404 0.0845
Brugia malayi probable homocysteine S-methyltransferase 0.0034 0.024 0.0501
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0225 0.5536
Plasmodium falciparum homocysteine S-methyltransferase, putative 0.0034 0.024 0.0501
Echinococcus granulosus Ankyrin 0.0016 0.0039 0.0081
Trypanosoma cruzi trypanothione reductase, putative 0.0049 0.0404 0.084
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0266 0.1785
Onchocerca volvulus 0.002 0.0075 0.0158
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0404 0.084
Loa Loa (eye worm) hypothetical protein 0.003 0.0195 0.0407
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0033 0.0225 0.047
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0223 0.1495
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.3173 1
Treponema pallidum NADH oxidase 0.0049 0.0404 0.1266
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0601 0.1894
Schistosoma mansoni hypothetical protein 0.0034 0.024 0.0501
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0266 0.0551
Echinococcus multilocularis RUN 0.002 0.0075 0.0075
Schistosoma mansoni intermediate filament proteins 0.003 0.0195 0.0407
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0266 0.0551
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0601 0.1257
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0129 0.0269
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0049 0.0404 0.0845
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0013 0.0002 0.0005
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0067 0.0136
Trypanosoma brucei unspecified product 0.0034 0.024 0.0497
Schistosoma mansoni rab6-interacting 0.002 0.0075 0.0158
Trichomonas vaginalis set domain proteins, putative 0.0267 0.282 0.8889
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0021 0.0092 0.0192
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0049 0.0404 0.084
Loa Loa (eye worm) hypothetical protein 0.0034 0.024 0.0503
Leishmania major DNA polymerase eta, putative 0.0019 0.0067 0.0136
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.01 0.0972 0.2034
Toxoplasma gondii thioredoxin reductase 0.0142 0.1435 0.3001
Plasmodium falciparum gamma-glutamylcysteine synthetase 0.0443 0.478 1
Echinococcus multilocularis lamin dm0 0.003 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.003 0.0189 0.0394
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0013 0.0002 0.0008
Schistosoma mansoni inositol monophosphatase 0.0037 0.0266 0.0556
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0049 0.0404 0.084
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0005
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0231 0.0483
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0002 0.0008
Loa Loa (eye worm) CYP4Cod1 0.0014 0.0011 0.0023
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0225 0.0708
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0307 0.0307
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0002 0.0005
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0037 0.0265 0.6531
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0067 0.0136
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0075 0.0158
Echinococcus granulosus chromobox protein 1 0.0078 0.0729 0.1525
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0049 0.0404 0.0845
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0036 0.0259 0.0542
Trypanosoma cruzi cytidine triphosphate synthase, putative 0.0034 0.024 0.0496
Loa Loa (eye worm) hypothetical protein 0.0019 0.0067 0.0141
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0223 0.1495
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0225 0.0708
Toxoplasma gondii exonuclease III APE 0.0037 0.0265 0.0554
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0013 0.0002 0.0005
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0036 0.0259 0.0542
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0013 0.0002 0.0002
Entamoeba histolytica hypothetical protein 0.0041 0.0307 0.0969
Loa Loa (eye worm) 6-phosphofructokinase 0.0122 0.1217 0.2546
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.3173 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0002 0.0005
Mycobacterium ulcerans 6-phosphofructokinase 0.0122 0.1217 0.8237
Brugia malayi glutathione reductase 0.0142 0.1435 0.3001
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0404 1
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0225 0.047
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1217 0.3836
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0036 0.0075
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.0122 0.1217 0.2542
Brugia malayi hypothetical protein 0.0041 0.0307 0.0643
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0015 0.002 0.0042
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0013 0.0002 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0266 0.0837
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.0002 0.0008
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0266 0.0556
Echinococcus multilocularis chromobox protein 1 0.0078 0.0729 0.0729
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.3173 1
Trypanosoma cruzi gamma-glutamylcysteine synthetase, putative 0.0443 0.478 1
Echinococcus multilocularis Glycoside hydrolase, family 27 0.01 0.0972 0.0972
Schistosoma mansoni lipoxygenase 0.0082 0.0769 0.1608
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0404 0.0841
Brugia malayi Immunoglobulin I-set domain containing protein 0.0016 0.0037 0.0078
Schistosoma mansoni hypothetical protein 0.0016 0.0037 0.0078
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0038 0.008
Giardia lamblia Fructose-bisphosphate aldolase 0.0298 0.3173 0.6636
Brugia malayi Melibiase family protein 0.0067 0.0601 0.1257
Plasmodium falciparum ferrodoxin reductase-like protein 0.0013 0.0002 0.0005
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.1477 1
Trypanosoma brucei unspecified product 0.0019 0.0067 0.0136
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0002 0.0005
Treponema pallidum exodeoxyribonuclease (exoA) 0.0037 0.0265 0.0827
Schistosoma mansoni inositol monophosphatase 0.0037 0.0266 0.0556
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0049 0.0404 0.0841
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0124 0.0124
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0037 0.0265 0.0554
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0067 0.0141
Brugia malayi hypothetical protein 0.0024 0.0129 0.0269
Mycobacterium leprae Probable 5-methyltetrahydrofolate--homocystein methyltransferase MetH (Methionine synthase, vitamin-B12 dependent isozyme) (MS) 0.0034 0.024 0.1609
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.0231 0.0231
Trypanosoma cruzi trypanothione reductase, putative 0.0142 0.1435 0.2998
Plasmodium vivax gamma-glutamylcysteine synthetase, putative 0.0443 0.478 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Echinococcus multilocularis thioredoxin glutathione reductase 0.0142 0.1435 0.1435
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0266 0.0837
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0013 0.0002 0.0008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0037 0.0265 0.0549
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.0122 0.1217 0.8237
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1217 0.3836
Brugia malayi intermediate filament protein 0.003 0.0195 0.0407
Loa Loa (eye worm) RecQ helicase 0.0024 0.0124 0.026
Toxoplasma gondii phosphofructokinase PFKII 0.0033 0.0225 0.047
Loa Loa (eye worm) hypothetical protein 0.0357 0.3825 0.8003
Mycobacterium ulcerans B12-dependent methionine synthase 0.0034 0.024 0.1609
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0037 0.0265 0.0554
Loa Loa (eye worm) hypothetical protein 0.0024 0.0129 0.0269
Loa Loa (eye worm) hypothetical protein 0.0034 0.024 0.0501
Loa Loa (eye worm) inositol-1 0.0037 0.0266 0.0556
Schistosoma mansoni DNA polymerase eta 0.0019 0.0067 0.0141
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0129 0.0269
Plasmodium vivax ferrodoxin reductase, putative 0.0013 0.0002 0.0005
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0013 0.0002 0.0005
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0002 0.0002
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0083 0.0778 0.0778
Leishmania major methionine synthase, putative 0.0034 0.024 0.0496
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Echinococcus multilocularis glutamate cysteine ligase, catalytic subunit 0.0443 0.478 0.478
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0729 0.2297
Plasmodium falciparum glutathione reductase 0.0142 0.1435 0.3001
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0225 0.0708
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0049 0.0404 0.0845
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.0002 0.0005
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0298 0.3173 1
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0075 0.0158
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0266 0.0556
Brugia malayi 6-phosphofructokinase 0.0122 0.1217 0.2546
Trypanosoma brucei trypanothione reductase 0.0142 0.1435 0.2998
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0203 0.0641
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0049 0.0404 0.2723
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.3173 1
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0049 0.0404 0.2723
Echinococcus multilocularis dna polymerase eta 0.0019 0.0067 0.0067
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0067 0.0141
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1217 0.3836
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.0067 0.0213
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0307 0.0643
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0124 0.0392
Echinococcus granulosus chromobox protein 1 0.0078 0.0729 0.1525
Onchocerca volvulus 0.0013 0.0002 0.0005
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0049 0.0404 0.0404
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0049 0.0404 0.0841
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.01 0.0972 0.0972
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0129 0.0269
Brugia malayi Cytochrome P450 family protein 0.0014 0.0011 0.0023
Plasmodium vivax homocysteine S-methyltransferase, putative 0.0034 0.024 0.0501
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0037 0.0265 0.0549
Loa Loa (eye worm) hypothetical protein 0.002 0.0075 0.0158
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0067 0.0141
Loa Loa (eye worm) hypothetical protein 0.0034 0.0231 0.0483
Trichomonas vaginalis glutamate synthase, putative 0.0013 0.0002 0.0008
Toxoplasma gondii selenide, water dikinase 0.0013 0.0002 0.0005
Brugia malayi Heterochromatin protein 1 0.0078 0.0729 0.1525
Echinococcus granulosus Chromobox protein 3 0.0013 0.00000002602 0.000000054438
Brugia malayi hypothetical protein 0.0016 0.0033 0.0068
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0195 0.0407
Onchocerca volvulus 0.003 0.0195 0.0407
Loa Loa (eye worm) phosphofructokinase 0.0122 0.1217 0.2546
Echinococcus granulosus geminin 0.0164 0.1682 0.3519
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Trypanosoma brucei gamma-glutamylcysteine synthetase 0.0443 0.478 1
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0037 0.0265 0.0834
Echinococcus granulosus dna polymerase kappa 0.0019 0.0067 0.0141
Schistosoma mansoni lamin 0.003 0.0195 0.0407
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0038 0.0079
Schistosoma mansoni loxhd1 0.002 0.0075 0.0158
Trypanosoma brucei homocysteine S-methyltransferase, putative 0.0034 0.024 0.0497
Plasmodium vivax glutathione reductase, putative 0.0142 0.1435 0.3001
Schistosoma mansoni hypothetical protein 0.0164 0.1682 0.3519
Echinococcus granulosus lamin dm0 0.003 0.0195 0.0407
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0016 0.0039 0.0081
Echinococcus multilocularis musashi 0.003 0.0195 0.0195
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Plasmodium falciparum thioredoxin reductase 0.0142 0.1435 0.3001
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.0002 0.0008
Loa Loa (eye worm) hypothetical protein 0.0019 0.007 0.0147
Brugia malayi Pre-SET motif family protein 0.0234 0.2461 0.5148
Entamoeba histolytica disulphide oxidoreductase, putative 0.0013 0.0002 0.0008
Trypanosoma cruzi gamma-glutamylcysteine synthetase, putative 0.0443 0.478 1
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.0231 0.0483
Brugia malayi 6-phosphofructokinase 0.0122 0.1217 0.2546
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0049 0.0404 0.2723
Echinococcus granulosus nuclear factor of activated T cells 5 0.0083 0.0778 0.1629
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0049 0.0404 0.2723
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0404 0.084
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0972 0.2034
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0038 0.008
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Echinococcus multilocularis glutamate synthase 0.0013 0.0002 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0002 0.0003
Brugia malayi SET domain containing protein 0.0014 0.0014 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1217 0.3836
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0002 0.0008
Brugia malayi Inositol-1 0.0037 0.0266 0.0556
Loa Loa (eye worm) heterochromatin protein 1 0.0078 0.0729 0.1525
Echinococcus granulosus death domain containing protein 0.0016 0.0037 0.0078
Echinococcus multilocularis Ankyrin 0.0016 0.0039 0.0039
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0013 0.0002 0.0002
Echinococcus multilocularis netrin receptor unc 5 0.0016 0.0037 0.0037
Plasmodium vivax SET domain protein, putative 0.0034 0.0231 0.0483
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.0067 0.0213
Brugia malayi Death domain containing protein 0.0016 0.0037 0.0078
Echinococcus granulosus glutamate cysteine ligase catalytic subunit 0.0443 0.478 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0075 0.0075
Giardia lamblia Glutamate-cysteine ligase 0.0443 0.478 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0231 0.0483
Schistosoma mansoni sulfide quinone reductase 0.0013 0.0002 0.0005
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0002 0.0008
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0011 0.0023
Schistosoma mansoni glutamate-cysteine ligase 0.0443 0.478 1
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0049 0.0404 0.0845
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0067 0.0441
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0013 0.0002 0.0005
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0049 0.0404 0.2723
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0067 0.0136
Plasmodium falciparum thioredoxin reductase 0.0049 0.0404 0.0845
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0067 0.0141
Schistosoma mansoni 6-phosphofructokinase 0.0122 0.1217 0.2546
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0013 0.0002 0.0005
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0383 0.1207
Echinococcus granulosus intermediate filament protein 0.003 0.0195 0.0407
Schistosoma mansoni hypothetical protein 0.0013 0.0002 0.0005
Schistosoma mansoni hypothetical protein 0.0164 0.1682 0.3519
Schistosoma mansoni glutamate synthase 0.0013 0.0002 0.0005
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0013 0.0002 0.0008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.3173 1
Leishmania major hypothetical protein, conserved 0.0024 0.0129 0.0264
Loa Loa (eye worm) hypothetical protein 0.0067 0.0601 0.1257
Giardia lamblia NADH oxidase lateral transfer candidate 0.0049 0.0404 0.084
Schistosoma mansoni ap endonuclease 0.0037 0.0265 0.0554
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0002 0.0008
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0122 0.1217 0.3831
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0404 0.084
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0265 0.0834
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.3173 1
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.0002 0.0008
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0037 0.0265 0.0549
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.0122 0.1217 0.2542
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0067 0.0441
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0225 0.0708
Loa Loa (eye worm) hypothetical protein 0.0016 0.0037 0.0078
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.3173 1
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0124 0.026
Trichomonas vaginalis chromobox protein, putative 0.0078 0.0729 0.2297
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0075 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.1477 1
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0013 0.0002 0.0005
Echinococcus granulosus RUN 0.002 0.0075 0.0158
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0033 0.0225 0.0465
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0067 0.0141
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Trichomonas vaginalis chromobox protein, putative 0.0047 0.0383 0.1207
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0037 0.0265 0.1778
Giardia lamblia DINP protein human, muc B family 0.0019 0.0067 0.0136
Loa Loa (eye worm) doublecortin family protein 0.002 0.0075 0.0158
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0016 0.0037 0.0078
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0225 0.0708
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0266 0.0266
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.3173 1
Onchocerca volvulus 0.0046 0.0373 0.0781
Leishmania major ATP-dependent phosphofructokinase 0.0122 0.1217 0.2542
Brugia malayi glutamate synthase 0.0013 0.0002 0.0005
Brugia malayi phosphofructokinase 0.0122 0.1217 0.2546
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0013 0.0002 0.0002
Brugia malayi Cytochrome P450 family protein 0.0014 0.0011 0.0023
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0049 0.0404 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0404 0.084
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0033 0.0225 0.0708
Schistosoma mansoni lamin 0.003 0.0195 0.0407
Onchocerca volvulus 0.0267 0.2822 0.5903
Schistosoma mansoni 6-phosphofructokinase 0.0122 0.1217 0.2546
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0129 0.0264
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0124 0.0392
Treponema pallidum fructose-bisphosphate aldolase 0.0298 0.3173 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0014 0.0011 0.006
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0013 0.0002 0.0005
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0013 0.0002 0.0005
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0002 0.0008
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0263 0.2784 0.5825
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0404 0.084
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0225 0.047
Brugia malayi hypothetical protein 0.0013 0.0002 0.0003
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0075 0.0158
Loa Loa (eye worm) glutathione reductase 0.0142 0.1435 0.3001
Echinococcus granulosus netrin receptor unc 5 0.0016 0.0037 0.0078
Brugia malayi hypothetical protein 0.0137 0.138 0.2887
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0049 0.0404 1
Echinococcus granulosus lamin 0.003 0.0195 0.0407
Leishmania major trypanothione reductase 0.0142 0.1435 0.2998
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0972 0.2034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0404 0.084
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0013 0.0002 0.0005
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0013 0.0002 0.0008
Echinococcus granulosus glutamate synthase 0.0013 0.0002 0.0005
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0265 0.0554
Loa Loa (eye worm) hypothetical protein 0.0044 0.0346 0.0724
Schistosoma mansoni ankyrin 23/unc44 0.0016 0.0037 0.0078
Loa Loa (eye worm) intermediate filament protein 0.003 0.0195 0.0407
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0037 0.0265 0.0549
Onchocerca volvulus 0.0034 0.024 0.0503
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Echinococcus multilocularis 6 phosphofructokinase 0.0122 0.1217 0.1217
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0067 0.0441
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0217 0.0454
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0049 0.0404 0.084
Leishmania major homocysteine S-methyltransferase, putative 0.0034 0.024 0.0496
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0117 0.1161 0.2429
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0049 0.0404 0.0845
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0298 0.3173 1
Brugia malayi hypothetical protein 0.002 0.0075 0.0158
Trichomonas vaginalis glutathione reductase, putative 0.0049 0.0404 0.1273
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.0231 0.0483
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.1477 1
Echinococcus multilocularis chromobox protein 1 0.0078 0.0729 0.0729
Trichomonas vaginalis phosphofructokinase, putative 0.0122 0.1217 0.3836
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.0122 0.1217 0.8237
Schistosoma mansoni blooms syndrome DNA helicase 0.0019 0.0068 0.0142
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1217 0.3836
Plasmodium vivax thioredoxin reductase, putative 0.0142 0.1435 0.3001
Echinococcus multilocularis geminin 0.0164 0.1682 0.1682
Leishmania major DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Loa Loa (eye worm) glutamate-cysteine ligase 0.0443 0.478 1
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0049 0.0404 0.0845
Onchocerca volvulus 0.003 0.0195 0.0407
Leishmania major cytochrome p450-like protein 0.0014 0.0011 0.0018
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0013 0.0002 0.0005
Echinococcus multilocularis lamin 0.003 0.0195 0.0195
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0037 0.0265 0.0549
Schistosoma mansoni glutamate synthase 0.0013 0.0002 0.0005
Toxoplasma gondii 6-phosphofructokinase 0.0033 0.0225 0.047
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0972 0.2034
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0404 0.084
Brugia malayi hypothetical protein 0.002 0.0075 0.0158
Echinococcus granulosus thioredoxin glutathione reductase 0.0142 0.1435 0.3001
Plasmodium falciparum glutathione reductase 0.0049 0.0404 0.0845
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0013 0.0002 0.0002
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0033 0.0225 0.0708
Brugia malayi Doublecortin family protein 0.002 0.0075 0.0158
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.0067 0.0213
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0266 0.0551
Onchocerca volvulus Netrin receptor homolog 0.0016 0.0037 0.0078
Toxoplasma gondii Alpha-galactosidase 0.0014 0.0015 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0075 0.0158
Toxoplasma gondii NADPH-glutathione reductase 0.0049 0.0404 0.0845
Trypanosoma cruzi homocysteine S-methyltransferase, putative 0.0034 0.024 0.0496
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0129 0.0265
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0129 0.0264
Toxoplasma gondii melibiase subfamily protein 0.01 0.0972 0.2034
Onchocerca volvulus 0.002 0.0075 0.0158
Loa Loa (eye worm) thioredoxin reductase 0.0142 0.1435 0.3001
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0972 0.2034
Brugia malayi Pre-SET motif family protein 0.0034 0.0231 0.0483
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.0067 0.0136
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.0231 0.0483
Echinococcus granulosus bloom syndrome protein 0.0024 0.0124 0.026
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0075 0.0158
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0266 0.6555
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0037 0.0265 0.0554
Brugia malayi chromobox protein homolog 3 0.0044 0.0346 0.0724
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0266 0.0837
Loa Loa (eye worm) programmed cell death 8 0.0013 0.0002 0.0005
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0601 0.1257
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0346 0.109
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0203 0.0641
Schistosoma mansoni disulfide oxidoreductase 0.0013 0.0002 0.0005
Brugia malayi exodeoxyribonuclease III family protein 0.0037 0.0265 0.0554
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.0067 0.0136
Plasmodium vivax 6-phosphofructokinase, putative 0.0033 0.0225 0.047
Loa Loa (eye worm) hypothetical protein 0.0014 0.0014 0.0029
Trichomonas vaginalis apoptosis inducing factor, putative 0.0013 0.0002 0.0008
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Trichomonas vaginalis phosphofructokinase, putative 0.0033 0.0225 0.0708
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0013 0.0002 0.0005
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0013 0.0002 0.0005
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0117 0.1161 0.1161
Entamoeba histolytica hypothetical protein 0.0041 0.0307 0.0969
Mycobacterium tuberculosis Probable oxidoreductase 0.0049 0.0404 0.2723
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0013 0.0002 0.0008
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0075 0.0158
Schistosoma mansoni polycystin 1-related 0.002 0.0075 0.0158
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0033 0.0225 0.047
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0049 0.0404 0.0845
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0013 0.0002 0.0005
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0266 0.0837
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0015 0.0032
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0049 0.0404 0.084
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0033 0.0225 0.5536
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0195 0.0407
Schistosoma mansoni ap endonuclease 0.0037 0.0265 0.0554
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0067 0.0441
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0067 0.0141
Schistosoma mansoni lipoxygenase 0.0117 0.1161 0.2429
Schistosoma mansoni sulfide quinone reductase 0.0013 0.0002 0.0005
Toxoplasma gondii glutamate-cysteine ligase, catalytic subunit domain-containing protein 0.0443 0.478 1
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0234 0.2461 0.5148
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0013 0.0002 0.0008
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0013 0.0002 0.0008
Brugia malayi Protein kinase domain containing protein 0.0016 0.0037 0.0078
Entamoeba histolytica hypothetical protein 0.0041 0.0307 0.0969
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0044 0.0346 0.0724
Toxoplasma gondii homocysteine s-methyltransferase domain-containing protein 0.0034 0.024 0.0501
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0013 0.0002 0.0008
Trypanosoma brucei cytochrome P450, putative 0.0014 0.0011 0.0019
Schistosoma mansoni hypothetical protein 0.002 0.0075 0.0158
Brugia malayi glutamate--cysteine ligase 0.0443 0.478 1
Trichomonas vaginalis mercuric reductase, putative 0.0049 0.0404 0.1273
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0013 0.0002 0.0005
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0037 0.0265 0.0265
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0067 0.0136
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0033 0.0225 0.0701
Echinococcus multilocularis Chromobox protein 3 0.0013 0.00000002602 0.00000002602
Loa Loa (eye worm) 6-phosphofructokinase 0.0122 0.1217 0.2546
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0049 0.0404 0.084
Entamoeba histolytica phosphofructokinase, putative 0.0122 0.1217 0.3836
Schistosoma mansoni chromobox protein 0.0078 0.0729 0.1525
Brugia malayi Uncoordinated protein 44 0.0016 0.0037 0.0078
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0013 0.0002 0.0002
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0307 0.0643
Echinococcus granulosus dna polymerase eta 0.0019 0.0067 0.0141
Loa Loa (eye worm) hypothetical protein 0.0016 0.0039 0.0081
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0075 0.0075
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0016 0.0037 0.0037
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0129 0.0269
Schistosoma mansoni glutamate synthase 0.0013 0.0002 0.0005
Schistosoma mansoni netrin receptor unc5 0.0016 0.0037 0.0078
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0047 0.0383 0.0801
Entamoeba histolytica hypothetical protein 0.0041 0.0307 0.0969
Schistosoma mansoni hypothetical protein 0.0041 0.0307 0.0643
Loa Loa (eye worm) cytochrome P450 family protein 0.0014 0.0011 0.0023
Brugia malayi follicle stimulating hormone receptor 0.0263 0.2784 0.5825
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0067 0.0067
Schistosoma mansoni rab6-interacting 0.002 0.0075 0.0158
Schistosoma mansoni chromobox protein 0.0078 0.0729 0.1525
Trichomonas vaginalis ap endonuclease, putative 0.0037 0.0265 0.0834
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0067 0.0136
Entamoeba histolytica thioredoxin reductase, putative 0.0013 0.0002 0.0008
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0046 0.0373 0.0781
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0049 0.0404 0.2723
Trypanosoma cruzi cytochrome P450, putative 0.0014 0.0011 0.0018

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 4.6535 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.