Detailed information for compound 1588028

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 364.391 | Formula: C22H20O5
  • H donors: 0 H acceptors: 1 LogP: 4.28 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: CC1CC(C=C1c1ccc2c(c1)OCO2)(C)C(=O)c1ccc2c(c1)OCO2
  • InChi: 1S/C22H20O5/c1-13-9-22(2,21(23)15-4-6-18-20(8-15)27-12-25-18)10-16(13)14-3-5-17-19(7-14)26-11-24-17/h3-8,10,13H,9,11-12H2,1-2H3
  • InChiKey: IOSAAFIPMQXNTE-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Schistosoma mansoni cpg binding protein 0.0032 0.0265 0.0387
Loa Loa (eye worm) hypothetical protein 0.0198 0.2264 0.3308
Brugia malayi hypothetical protein 0.0017 0.0084 0.0123
Trypanosoma cruzi phytoene synthase, putative 0.0086 0.0912 0.283
Onchocerca volvulus 0.0039 0.0349 0.1272
Brugia malayi hypothetical protein 0.0017 0.0088 0.0128
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0062 0.0631 0.3276
Onchocerca volvulus 0.0037 0.0328 0.1197
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Brugia malayi hypothetical protein 0.0039 0.0349 0.0509
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0328 0.0328
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0086 0.0912 0.1333
Schistosoma mansoni hypothetical protein 0.0032 0.0269 0.0393
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0037 0.0328 0.0479
Schistosoma mansoni acetylcholinesterase 0.0039 0.0349 0.0509
Schistosoma mansoni neurotransmitter gated ion channel 0.0017 0.0088 0.0128
Loa Loa (eye worm) acetylcholinesterase 1 0.0148 0.1663 0.243
Echinococcus multilocularis slit 2 protein 0.0025 0.0178 0.0178
Brugia malayi hypothetical protein 0.0017 0.0088 0.0128
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0039 0.0349 0.0509
Schistosoma mansoni neuroligin 3 (S09 family) 0.0039 0.0349 0.0509
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0269 0.0393
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.1123 1
Brugia malayi aspartic protease BmAsp-1, identical 0.0017 0.0084 0.0123
Echinococcus granulosus nAChR subunit 0.002 0.0122 0.0179
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.0088 0.0128
Echinococcus granulosus cpg binding protein 0.0032 0.0265 0.0387
Onchocerca volvulus 0.0039 0.0349 0.1272
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0007 0.0011
Loa Loa (eye worm) hypothetical protein 0.002 0.0122 0.0179
Onchocerca volvulus 0.0017 0.0084 0.0307
Schistosoma mansoni memapsin-2 (A01 family) 0.0419 0.4913 0.718
Brugia malayi Carboxylesterase family protein 0.0039 0.0349 0.0509
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0132 0.0193
Onchocerca volvulus 0.0021 0.0132 0.0482
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0132 0.0132
Brugia malayi Thrombospondin N-terminal -like domain containing protein 0.0025 0.0178 0.026
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0132 0.0193
Brugia malayi cytochrome P450 0.0011 0.0014 0.0021
Onchocerca volvulus 0.0017 0.0084 0.0307
Echinococcus granulosus neuroligin 0.0039 0.0349 0.0509
Onchocerca volvulus 0.0037 0.0328 0.1197
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0132 0.0193
Echinococcus multilocularis neurogenic locus notch protein 0.0025 0.0178 0.0178
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0132 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0132 0.0193
Echinococcus granulosus Niemann Pick C1 protein 0.0148 0.1656 0.242
Echinococcus granulosus pikachurin 0.0025 0.0178 0.026
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Trypanosoma brucei squalene synthase, putative 0.0275 0.3186 1
Echinococcus granulosus cytochrome P450 2K1 0.0011 0.0014 0.0021
Schistosoma mansoni hypothetical protein 0.0043 0.0396 0.0578
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0037 0.0328 0.0479
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0017 0.0088 0.0128
Loa Loa (eye worm) ACC-1 protein 0.0037 0.0328 0.0479
Brugia malayi Carboxylesterase family protein 0.0039 0.0349 0.0509
Brugia malayi steroid hormone receptor 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0105 1
Schistosoma mansoni nAChR subunit 0.0037 0.0328 0.0479
Brugia malayi EGF-like domain containing protein 0.0025 0.0178 0.026
Schistosoma mansoni hypothetical protein 0.0178 0.2019 0.295
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0105 0.0285
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0039 0.0349 0.0509
Echinococcus granulosus para nitrobenzyl esterase 0.0039 0.0349 0.0509
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0328 0.0479
Brugia malayi ecdysteroid receptor 0.0021 0.0132 0.0193
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.002 0.0122 0.0179
Echinococcus multilocularis ubiquitin specific protease 41 0.0042 0.0386 0.0386
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0269 0.0393
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0328 0.0479
Brugia malayi nuclear receptor NHR-88 0.0021 0.0132 0.0193
Onchocerca volvulus 0.0037 0.0328 0.1197
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0424 0.0619
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0386 0.1172
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0105 0.0105
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0132 0.0193
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0105 0.048
Onchocerca volvulus 0.0039 0.0349 0.1272
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0249 0.0249
Loa Loa (eye worm) hypothetical protein 0.0039 0.0349 0.0509
Echinococcus granulosus geminin 0.0178 0.2019 0.295
Echinococcus multilocularis nAChR subunit 0.002 0.0122 0.0122
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0132 0.0193
Onchocerca volvulus 0.002 0.0122 0.0446
Loa Loa (eye worm) hypothetical protein 0.002 0.0122 0.0179
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0132 0.0193
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0105 0.0285
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0415 0.0415
Loa Loa (eye worm) hypothetical protein 0.002 0.0122 0.0179
Loa Loa (eye worm) GABA receptor subunit 0.002 0.0122 0.0179
Brugia malayi laminin alpha chain 0.0025 0.0178 0.026
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0062 0.0631 0.0923
Loa Loa (eye worm) aspartic protease BmAsp-1 0.0017 0.0084 0.0123
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0037 0.0328 0.0328
Brugia malayi Pre-SET motif family protein 0.0031 0.0249 0.0364
Brugia malayi CXXC zinc finger family protein 0.003 0.0244 0.0357
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0037 0.0328 0.0328
Onchocerca volvulus 0.0017 0.0088 0.032
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0132 0.0132
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0105 0.1143 0.167
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0631 0.0923
Schistosoma mansoni hypothetical protein 0.0032 0.0269 0.0393
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.1123 0.1123
Echinococcus multilocularis acetylcholinesterase 0.0148 0.1663 0.1663
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0386 0.0564
Loa Loa (eye worm) hypothetical protein 0.002 0.0122 0.0179
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0042 0.0386 0.0564
Echinococcus granulosus carboxylesterase 5A 0.0148 0.1663 0.243
Loa Loa (eye worm) hypothetical protein 0.0044 0.0415 0.0606
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0037 0.0328 0.0479
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0042 0.0386 0.2761
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0328 0.0479
Schistosoma mansoni ap endonuclease 0.0019 0.0105 0.0153
Loa Loa (eye worm) LGC-31 protein 0.0037 0.0328 0.0479
Schistosoma mansoni acetylcholine receptor subunit beta 0.0017 0.0088 0.0128
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0328 0.0479
Brugia malayi Carboxylesterase family protein 0.0039 0.0349 0.0509
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0132 0.0193
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0328 0.0328
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.0017 0.0084 0.1132
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0132 0.0193
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0037 0.0328 0.0328
Schistosoma mansoni cathepsin D (A01 family) 0.0017 0.0084 0.0123
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0105 0.5
Loa Loa (eye worm) hypothetical protein 0.002 0.0122 0.0179
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Loa Loa (eye worm) CYP4Cod1 0.0011 0.0014 0.0021
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0132 0.0193
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0228 0.0333
Trichomonas vaginalis spcc417.12 protein, putative 0.0039 0.0349 0.0996
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Mycobacterium tuberculosis Probable phytoene synthase PhyA 0.0086 0.0912 0.4765
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0037 0.0328 0.0328
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0037 0.0328 0.0479
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0424 0.0619
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0037 0.0328 0.0479
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Onchocerca volvulus 0.0238 0.274 1
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0037 0.0328 0.0479
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0014 0.0014
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0037 0.0328 0.0479
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.002 0.0122 0.0179
Loa Loa (eye worm) hypothetical protein 0.0017 0.0084 0.0123
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Echinococcus multilocularis glycine receptor subunit beta 0.0037 0.0328 0.0328
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0017 0.0088 0.0088
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0037 0.0328 0.0328
Echinococcus granulosus glycine receptor subunit beta 0.0037 0.0328 0.0479
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0132 0.0132
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0017 0.0088 0.0128
Leishmania major squalene synthase, putative 0.0275 0.3186 1
Brugia malayi Pepsin A precursor 0.0017 0.0084 0.0123
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0193
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0132 0.0193
Schistosoma mansoni ap endonuclease 0.0019 0.0105 0.0153
Schistosoma mansoni acetylcholine receptor-related 0.0017 0.0088 0.0128
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Schistosoma mansoni nAChR subunit 0.0037 0.0328 0.0479
Echinococcus granulosus glycine receptor subunit beta 0.0037 0.0328 0.0479
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0424 0.0619
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.002 0.0122 0.0179
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0415 0.0606
Loa Loa (eye worm) cytochrome P450 family protein 0.0011 0.0014 0.0021
Schistosoma mansoni nAChR subunit 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0039 0.0349 0.0509
Schistosoma mansoni nAChR subunit 0.0037 0.0328 0.0479
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0017 0.0088 0.0128
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0039 0.0349 0.0509
Brugia malayi Cation transporter family protein 0.0037 0.0328 0.0479
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0037 0.0328 0.0479
Loa Loa (eye worm) carboxylesterase 0.0148 0.1663 0.243
Echinococcus multilocularis neuroligin 0.0039 0.0349 0.0349
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0037 0.0328 0.0479
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0386 0.1137
Loa Loa (eye worm) hypothetical protein 0.002 0.0122 0.0179
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0039 0.0349 0.0509
Loa Loa (eye worm) histone methyltransferase 0.001 0.0007 0.0011
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0122 0.0179
Onchocerca volvulus Putative nachr subunit 0.0037 0.0328 0.1197
Brugia malayi Carboxylesterase family protein 0.0148 0.1663 0.243
Brugia malayi nuclear hormone receptor 0.0021 0.0132 0.0193
Toxoplasma gondii histone lysine methyltransferase SET1 0.0058 0.0581 0.9189
Toxoplasma gondii aspartyl protease ASP3 0.0017 0.0084 0.1132
Schistosoma mansoni hypothetical protein 0.0032 0.0269 0.0393
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0039 0.0349 0.0509
Loa Loa (eye worm) abnormal epIthelia family member 0.0025 0.0178 0.026
Loa Loa (eye worm) aspartyl protease 6 0.0017 0.0084 0.0123
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0132 0.0482
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0132 0.0482
Brugia malayi CHE-14 protein 0.0044 0.0415 0.0606
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0249 0.0249
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0037 0.0328 0.0479
Schistosoma mansoni slit 0.0025 0.0178 0.026
Echinococcus granulosus GPCR family 2 0.0032 0.0269 0.0393
Brugia malayi MH2 domain containing protein 0.0124 0.1372 0.2004
Schistosoma mansoni cpg binding protein 0.0032 0.0265 0.0387
Echinococcus granulosus acetylcholinesterase 0.0148 0.1663 0.243
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.1104 0.1613
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0269 0.0269
Mycobacterium ulcerans carboxylesterase, LipT 0.0168 0.1898 1
Echinococcus granulosus indoleamine 23 dioxygenase 2 0.058 0.6843 1
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0037 0.0328 0.0479
Toxoplasma gondii aspartyl protease 0.0017 0.0084 0.1132
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0424 0.0424
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0105 0.0285
Loa Loa (eye worm) cytochrome P450 family protein 0.0011 0.0014 0.0021
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.002 0.0122 0.0179
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0424 0.0424
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0132 0.0193
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0132 0.0193
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0037 0.0328 0.0479
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0424 0.0619
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0017 0.0088 0.0128
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0132 0.0193
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0017 0.0088 0.0088
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0132 0.0193
Onchocerca volvulus 0.0017 0.0088 0.032
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.002 0.0122 0.0179
Brugia malayi Eukaryotic aspartyl protease family protein 0.0017 0.0084 0.0123
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0014 0.0021
Schistosoma mansoni nAChR subunit 0.0017 0.0088 0.0128
Onchocerca volvulus 0.0039 0.0349 0.1272
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0348 0.4061 0.5934
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0132 0.0193
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0105 0.0285
Leishmania major hypothetical protein, conserved 0.0086 0.0912 0.283
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0007 0.0007
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0424 0.0619
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0328 0.0479
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0105 0.0153
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0132 0.0193
Echinococcus granulosus dnaJ subfamily B 0.043 0.504 0.7364
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0132 0.0193
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0037 0.0328 0.0479
Onchocerca volvulus 0.0031 0.0249 0.0909
Loa Loa (eye worm) cytochrome P450 0.0011 0.0014 0.0021
Mycobacterium ulcerans phytoene synthase, CrtB 0.0086 0.0912 0.4765
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0249 0.0364
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Echinococcus granulosus glycine receptor subunit alpha 1 0.0037 0.0328 0.0479
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0328 0.0479
Brugia malayi aspartic protease BmAsp-2, identical 0.0017 0.0084 0.0123
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0014 0.0021
Schistosoma mansoni gliotactin 0.0039 0.0349 0.0509
Schistosoma mansoni neurotransmitter gated ion channel 0.0017 0.0088 0.0128
Loa Loa (eye worm) hypothetical protein 0.0039 0.0349 0.0509
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.1104 0.1613
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0132 0.0193
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0037 0.0328 0.0479
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.1123 0.1642
Loa Loa (eye worm) hypothetical protein 0.0103 0.1123 0.1642
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0042 0.0386 0.0386
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0415 0.0606
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Echinococcus granulosus neurogenic locus notch protein 0.0025 0.0178 0.026
Schistosoma mansoni BC026374 protein (S09 family) 0.0039 0.0349 0.0509
Echinococcus granulosus Squalene phytoene synthase 0.0086 0.0912 0.1333
Loa Loa (eye worm) hypothetical protein 0.0181 0.2058 0.3008
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0249 0.0364
Loa Loa (eye worm) hypothetical protein 0.0031 0.0249 0.0364
Brugia malayi Carboxylesterase family protein 0.0039 0.0349 0.0509
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0014 0.0021
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.002 0.0122 0.0179
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0017 0.0084 0.0123
Schistosoma mansoni nAChR subunit 0.0017 0.0088 0.0128
Brugia malayi Cytochrome P450 family protein 0.0011 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0006 0.0009
Loa Loa (eye worm) hypothetical protein 0.0342 0.3985 0.5823
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0193
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0037 0.0328 0.0479
Onchocerca volvulus 0.0039 0.0349 0.1272
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0105 0.0077
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.0088 0.0128
Loa Loa (eye worm) hypothetical protein 0.0054 0.0535 0.0781
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0037 0.0328 0.0479
Echinococcus multilocularis BC026374 protein (S09 family) 0.0039 0.0349 0.0349
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0132 0.0132
Schistosoma mansoni nAChR subunit 0.0037 0.0328 0.0479
Echinococcus multilocularis geminin 0.0178 0.2019 0.2019
Loa Loa (eye worm) MH2 domain-containing protein 0.0124 0.1372 0.2004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0017 0.0084 0.1132
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0148 0.1663 0.243
Toxoplasma gondii aspartyl protease ASP1 0.0017 0.0084 0.1132
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0017 0.0088 0.0128
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0105 0.0077
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.1104 0.1613
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0193
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0386 0.0564
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0193
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0105 0.0153
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0386 0.1172
Brugia malayi indoleamine 2,3-dioxygenase 0.058 0.6843 1
Echinococcus multilocularis indoleamine 2,3 dioxygenase 2 0.058 0.6843 0.6843
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0037 0.0328 0.0479
Onchocerca volvulus 0.0017 0.0088 0.032
Loa Loa (eye worm) hypothetical protein 0.0017 0.0084 0.0123
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0132 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0132 0.0193
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0014 0.0021
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0017 0.0084 0.0084
Loa Loa (eye worm) hypothetical protein 0.0025 0.0178 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0102 0.1104 0.1613
Schistosoma mansoni cathepsin D (A01 family) 0.0017 0.0084 0.0123
Schistosoma mansoni cpg binding protein 0.003 0.0244 0.0357
Echinococcus multilocularis protein patched 0.0044 0.0415 0.0415
Brugia malayi hypothetical protein 0.0017 0.0088 0.0128
Echinococcus multilocularis Squalene phytoene synthase 0.0086 0.0912 0.0912
Schistosoma mansoni hypothetical protein 0.0043 0.0396 0.0578
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0249 0.0364
Trichomonas vaginalis set domain proteins, putative 0.0238 0.274 1
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0037 0.0328 0.0479
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0198 0.2264 0.3308
Echinococcus multilocularis 0.0011 0.0014 0.0014
Echinococcus multilocularis para nitrobenzyl esterase 0.0039 0.0349 0.0349
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0348 0.4061 0.5934
Brugia malayi hypothetical protein 0.0011 0.0014 0.0021
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0132 0.0193
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Entamoeba histolytica hypothetical protein 0.002 0.0122 0.0173
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0017 0.0084 0.0123
Mycobacterium leprae Conserved hypothetical protein 0.0011 0.0014 0.5
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0631 0.3276
Loa Loa (eye worm) indoleamine 2,3-dioxygenase 0.058 0.6843 1
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0037 0.0328 0.0479
Echinococcus multilocularis pikachurin 0.0025 0.0178 0.0178
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0039 0.0349 0.0509
Mycobacterium leprae putative cytochrome p450 0.0011 0.0014 0.5
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0132 0.0193
Brugia malayi hypothetical protein 0.0011 0.0014 0.0021
Echinococcus granulosus BC026374 protein S09 family 0.0039 0.0349 0.0509
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0132 0.0132
Schistosoma mansoni neurotransmitter gated ion channel 0.002 0.0122 0.0179
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0017 0.0088 0.0128
Brugia malayi Cytochrome P450 family protein 0.0011 0.0014 0.0021
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0039 0.0349 0.1775
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0039 0.0349 0.0996
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.1123 0.1642
Echinococcus multilocularis expressed conserved protein 0.0097 0.1048 0.1048
Loa Loa (eye worm) hypothetical protein 0.0042 0.0386 0.0564
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0132 0.0193
Onchocerca volvulus 0.0037 0.0328 0.1197
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0132 0.0193
Echinococcus granulosus acetylcholinesterase 0.0148 0.1663 0.243
Toxoplasma gondii aldehyde dehydrogenase 0.0062 0.0631 1
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0062 0.0631 0.0631
Loa Loa (eye worm) carboxylesterase 0.0039 0.0349 0.0509
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0037 0.0328 0.0328
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0017 0.0084 0.0123
Echinococcus granulosus ubiquitin specific protease 41 0.0042 0.0386 0.0564
Loa Loa (eye worm) ACC-1 protein 0.0037 0.0328 0.0479
Schistosoma mansoni laminin gamma-3 chain 0.0025 0.0178 0.026
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0132 0.0193
Schistosoma mansoni hypothetical protein 0.007 0.0717 0.1048
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0132 0.0193
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0348 0.4061 0.5934
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0269 0.0393
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0062 0.0631 0.1946
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0209 0.2394 0.3499
Loa Loa (eye worm) hypothetical protein 0.007 0.0717 0.1048
Loa Loa (eye worm) hypothetical protein 0.0025 0.0178 0.026
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0042 0.0386 1
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0132 0.0193
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0386 0.1137
Echinococcus granulosus slit 2 protein 0.0025 0.0178 0.026
Brugia malayi Cytochrome P450 family protein 0.0011 0.0014 0.0021
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0415 0.1245
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0269 0.0393
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0631 0.3276
Brugia malayi Cation transporter family protein 0.0037 0.0328 0.0479
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) carboxylesterase 0.0039 0.0349 0.0509
Schistosoma mansoni chondroitin sulfate proteoglycan-related 0.0025 0.0178 0.026
Schistosoma mansoni nAChR subunit 0.0037 0.0328 0.0479
Echinococcus multilocularis nAChR subunit 0.0037 0.0328 0.0328
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0037 0.0328 0.0328
Echinococcus multilocularis Niemann Pick C1 protein 0.0148 0.1656 0.1656
Schistosoma mansoni hypothetical protein 0.0086 0.0912 0.1333
Schistosoma mansoni cell polarity protein 0.0025 0.0178 0.026
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0039 0.0349 0.0349
Echinococcus granulosus expressed conserved protein 0.0097 0.1048 0.1532
Onchocerca volvulus 0.0037 0.0328 0.1197
Brugia malayi Cation transporter family protein 0.0037 0.0328 0.0479
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0039 0.0349 0.1775
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Schistosoma mansoni coup transcription factor 0.0021 0.0132 0.0193
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0017 0.0088 0.0128
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0042 0.0386 0.0386
Schistosoma mansoni hypothetical protein 0.0011 0.0014 0.0021
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0037 0.0328 0.0479
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0042 0.0386 0.0564
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) CXXC zinc finger family protein 0.003 0.0244 0.0357
Echinococcus multilocularis acetylcholinesterase 0.0148 0.1663 0.1663
Brugia malayi excitatory GABA receptor EXP-1A 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0249 0.3806
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0415 0.0606
Brugia malayi Carboxylesterase family protein 0.0148 0.1663 0.243
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0039 0.0349 0.0509
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0193
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0132 0.0482
Brugia malayi hypothetical protein 0.0017 0.0088 0.0128
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0424 0.0619
Trypanosoma cruzi squalene synthase, putative 0.0275 0.3186 1
Echinococcus multilocularis dnaJ subfamily B 0.043 0.504 0.504
Schistosoma mansoni aldehyde dehydrogenase 0.0062 0.0631 0.0923
Mycobacterium ulcerans aldehyde dehydrogenase 0.0062 0.0631 0.3276
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0032 0.0269 0.0393
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0042 0.0386 0.0564
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Brugia malayi Pre-SET motif family protein 0.0209 0.2394 0.3499
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0039 0.0349 0.0509
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Brugia malayi laminin-like protein K08C7.3 precursor 0.0025 0.0178 0.026
Loa Loa (eye worm) hypothetical protein 0.002 0.0122 0.0179
Schistosoma mansoni hypothetical protein 0.058 0.6843 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.0663 0.0969
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Toxoplasma gondii exonuclease III APE 0.0019 0.0105 0.1465
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0132 0.0193
Loa Loa (eye worm) hypothetical protein 0.0148 0.1663 0.243
Schistosoma mansoni hypothetical protein 0.043 0.504 0.7364
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0037 0.0328 0.0479
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0269 0.0269
Schistosoma mansoni hypothetical protein 0.0178 0.2019 0.295
Loa Loa (eye worm) hypothetical protein 0.0025 0.0178 0.026
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0021
Brugia malayi hypothetical protein 0.0017 0.0084 0.0123
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0042 0.0386 0.1172
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Schistosoma mansoni hypothetical protein 0.0032 0.0269 0.0393
Schistosoma mansoni nAChR subunit 0.0037 0.0328 0.0479
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0017 0.0088 0.0088
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0037 0.0328 0.0479
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0132 0.0193
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0132 0.0193
Echinococcus multilocularis GPCR, family 2 0.0032 0.0269 0.0269
Plasmodium vivax SET domain protein, putative 0.0031 0.0249 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0132 0.0132
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0132 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0132 0.0193
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0014 0.0021
Brugia malayi nuclear receptor RXR 0.0011 0.0014 0.0021
Echinococcus multilocularis glycine receptor subunit beta 0.0037 0.0328 0.0328
Schistosoma mansoni cytochrome P450 0.0011 0.0014 0.0021
Loa Loa (eye worm) hypothetical protein 0.0011 0.0014 0.0021
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0249 0.0364
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0037 0.0328 0.0479
Loa Loa (eye worm) hypothetical protein 0.0021 0.0132 0.0193
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0132 0.0132
Onchocerca volvulus NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog 0.0086 0.0912 0.3328
Onchocerca volvulus 0.002 0.0122 0.0446
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0014 0.0021
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0042 0.0386 0.1172
Echinococcus multilocularis protein dispatched 1 0.0051 0.049 0.049
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0424 0.0619
Schistosoma mansoni hypothetical protein 0.0043 0.0396 0.0578
Mycobacterium tuberculosis Carboxylesterase LipT 0.0168 0.1898 1
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0105 0.0153
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0132 0.0132
Loa Loa (eye worm) hypothetical protein 0.0148 0.1663 0.243
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0017 0.0084 0.0123
Loa Loa (eye worm) hypothetical protein 0.0017 0.0088 0.0128
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0105 0.1246
Echinococcus granulosus nAChR subunit 0.0037 0.0328 0.0479
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0132 0.0193
Onchocerca volvulus 0.0037 0.0328 0.1197
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0348 0.4061 0.5934
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0037 0.0328 0.0479
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0105 0.5
Brugia malayi Cytochrome P450 family protein 0.0011 0.0014 0.0021
Onchocerca volvulus 0.003 0.0244 0.0891
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0269 0.0393
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0037 0.0328 0.0328
Loa Loa (eye worm) transcription factor SMAD2 0.0124 0.1372 0.2004
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0132 0.0193
Schistosoma mansoni hypothetical protein 0.058 0.6843 1
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0717 0.1048
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0105 0.048
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0017 0.0088 0.0128
Schistosoma mansoni patched 1 0.0044 0.0415 0.0606
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0042 0.0386 0.1137
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0132 0.0193
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0132 0.0193
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0132 0.0193
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0249 0.0364
Echinococcus multilocularis cpg binding protein 0.0032 0.0265 0.0265
Loa Loa (eye worm) acetylcholine receptor protein 0.0017 0.0088 0.0128
Schistosoma mansoni hypothetical protein 0.0043 0.0396 0.0578
Trypanosoma cruzi squalene synthase, putative 0.0275 0.3186 1
Echinococcus multilocularis carboxylesterase 5A 0.0148 0.1663 0.1663
Loa Loa (eye worm) hypothetical protein 0.0037 0.0328 0.0479
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0348 0.4061 0.4061
Loa Loa (eye worm) cytochrome P450 family protein 0.0011 0.0014 0.0021
Brugia malayi hypothetical protein 0.0017 0.0088 0.0128

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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