Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | macrophage migration inhibitory factor, putative | 0.046 | 0.9324 | 1 |
Onchocerca volvulus | 0.007 | 0.1134 | 0.0877 | |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0342 | 0.6841 | 0.6841 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0027 | 0.0223 | 0.0108 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0023 | 0.0149 | 0.0113 |
Leishmania major | importin beta-1 subunit, putative | 0.0024 | 0.017 | 0.0051 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0023 | 0.0149 | 0.0113 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0492 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0034 | 0.0381 | 0.4292 |
Loa Loa (eye worm) | thyroglobulin type-1 repeat family protein | 0.007 | 0.1134 | 0.1134 |
Brugia malayi | Thyroglobulin type-1 repeat family protein | 0.007 | 0.1134 | 0.1023 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 0.5 |
Trichomonas vaginalis | macrophage migration inhibitory factor, mif, putative | 0.046 | 0.9324 | 1 |
Echinococcus multilocularis | importin subunit beta 1 | 0.003 | 0.0289 | 0.0254 |
Echinococcus granulosus | GPCR family 2 | 0.0045 | 0.0596 | 0.0562 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0078 | 0.1293 | 0.1982 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0071 | 0.116 | 0.1772 |
Brugia malayi | hypothetical protein | 0.0133 | 0.2459 | 0.2364 |
Echinococcus granulosus | lamin dm0 | 0.0057 | 0.0865 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0381 | 0.0381 |
Brugia malayi | RNA, U transporter 1 | 0.0085 | 0.1449 | 0.1343 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0034 | 0.0381 | 0.028 |
Onchocerca volvulus | Huntingtin homolog | 0.0133 | 0.2459 | 0.2421 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0596 | 0.0883 |
Giardia lamblia | Macrophage migration inhibitory factor | 0.046 | 0.9324 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0045 | 0.0596 | 0.0562 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0033 | 0.0351 | 0.0316 |
Brugia malayi | follicle stimulating hormone receptor | 0.023 | 0.4497 | 0.4429 |
Schistosoma mansoni | Smad4 | 0.0023 | 0.0149 | 0.0178 |
Schistosoma mansoni | lamin | 0.0057 | 0.0865 | 0.1306 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0466 | 0.0677 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0381 | 0.0381 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0028 | 0.0241 | 0.0205 |
Plasmodium vivax | SET domain protein, putative | 0.0056 | 0.0832 | 0.0771 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 0.1272 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0022 | 0.0123 | 0.0123 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0051 | 0.0724 | 0.0724 |
Brugia malayi | Pre-SET motif family protein | 0.0389 | 0.7831 | 0.7804 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0051 | 0.0724 | 1 |
Echinococcus granulosus | lamin | 0.0057 | 0.0865 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0596 | 0.0596 |
Plasmodium falciparum | macrophage migration inhibitory factor | 0.046 | 0.9324 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0289 | 0.2763 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0466 | 0.5704 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1293 | 0.1293 |
Plasmodium vivax | macrophage migration inhibitory factor, putative | 0.046 | 0.9324 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0071 | 0.116 | 0.1772 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0033 | 0.0351 | 0.0316 |
Brugia malayi | Pre-SET motif family protein | 0.0056 | 0.0832 | 0.0718 |
Echinococcus granulosus | importin subunit beta 1 | 0.003 | 0.0289 | 0.0254 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0051 | 0.0724 | 0.069 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0596 | 0.0883 |
Plasmodium vivax | importin-beta 2, putative | 0.003 | 0.0289 | 0.0181 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0342 | 0.6841 | 0.6841 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0051 | 0.0724 | 0.1085 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0071 | 0.116 | 0.1128 |
Brugia malayi | secreted modular calcium-binding protein 1 | 0.007 | 0.1134 | 0.1023 |
Mycobacterium leprae | conserved hypothetical protein | 0.0034 | 0.0381 | 0.1479 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0051 | 0.0724 | 0.0653 |
Brugia malayi | Bromodomain containing protein | 0.0035 | 0.0397 | 0.0277 |
Echinococcus multilocularis | musashi | 0.0057 | 0.0865 | 0.0831 |
Brugia malayi | MH2 domain containing protein | 0.0342 | 0.6841 | 0.6801 |
Brugia malayi | MAP kinase sur-1 | 0.0051 | 0.0724 | 0.0609 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 1 |
Schistosoma mansoni | smad1 5 8 and | 0.0023 | 0.0149 | 0.0178 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0038 | 0.0466 | 0.093 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0242 | 0.4757 | 0.4757 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0056 | 0.0832 | 0.1255 |
Onchocerca volvulus | 0.0057 | 0.0865 | 0.0563 | |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0034 | 0.0381 | 0.0346 |
Toxoplasma gondii | ABC1 family protein | 0.0034 | 0.0381 | 0.028 |
Brugia malayi | Bm-MIF-1, identical | 0.046 | 0.9324 | 0.9315 |
Entamoeba histolytica | hypothetical protein | 0.0024 | 0.017 | 0.0051 |
Echinococcus granulosus | snurportin 1 | 0.0319 | 0.6377 | 0.6363 |
Brugia malayi | MH2 domain containing protein | 0.0023 | 0.0149 | 0.0027 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0056 | 0.0832 | 0.0771 |
Echinococcus multilocularis | GPCR, family 2 | 0.0045 | 0.0596 | 0.0562 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0038 | 0.0466 | 0.0431 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0219 | 0.4267 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0466 | 0.0373 |
Onchocerca volvulus | 0.007 | 0.1134 | 0.0877 | |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0021 | 0.0094 | 0.0057 |
Loa Loa (eye worm) | hypothetical protein | 0.0065 | 0.1021 | 0.1021 |
Echinococcus multilocularis | snurportin 1 | 0.0319 | 0.6377 | 0.6363 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0071 | 0.116 | 0.1128 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 0.5 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0051 | 0.0731 | 0.0697 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0034 | 0.0381 | 0.4292 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.1293 | 0.1272 |
Echinococcus granulosus | intermediate filament protein | 0.0057 | 0.0865 | 0.0831 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0045 | 0.0596 | 0.0479 |
Brugia malayi | Importin beta-1 subunit | 0.003 | 0.0289 | 0.0168 |
Brugia malayi | Bromodomain containing protein | 0.0069 | 0.1103 | 0.0992 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0381 | 0.0381 |
Schistosoma mansoni | importin beta-1 | 0.003 | 0.0289 | 0.0398 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.1769 | 0.2733 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0038 | 0.0466 | 0.0373 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.046 | 0.9324 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0596 | 0.0883 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0051 | 0.0724 | 0.069 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0034 | 0.0382 | 0.1483 |
Brugia malayi | beta-lactamase family protein | 0.0034 | 0.0381 | 0.0261 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0055 | 0.0809 | 0.0775 |
Schistosoma mansoni | ran | 0.0022 | 0.0123 | 0.0136 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0034 | 0.0381 | 0.028 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.023 | 0.4497 | 0.4497 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0023 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0381 | 0.0381 |
Schistosoma mansoni | lamin | 0.0057 | 0.0865 | 0.1306 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0051 | 0.0724 | 0.0653 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0242 | 0.4757 | 0.4757 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 1 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.0724 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0045 | 0.0596 | 0.0479 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0045 | 0.0596 | 0.0596 |
Brugia malayi | Thyroglobulin type-1 repeat family protein | 0.007 | 0.1134 | 0.1023 |
Loa Loa (eye worm) | hypothetical protein | 0.0141 | 0.2619 | 0.2619 |
Brugia malayi | MH1 domain containing protein | 0.0023 | 0.0149 | 0.0027 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0096 | 0.1683 | 0.1579 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0045 | 0.0596 | 0.0562 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0055 | 0.0809 | 0.0775 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.017 | 0.0051 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0466 | 0.5704 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0021 | 0.0094 | 0.0057 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0023 | 0.0149 | 0.0178 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0023 | 0.0149 | 0.0149 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0051 | 0.0731 | 0.0899 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0034 | 0.0381 | 0.0261 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0031 | 0.0305 | 0.0184 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.003 | 0.0289 | 0.2763 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0466 | 0.5704 |
Brugia malayi | Smad1 | 0.0023 | 0.0149 | 0.0027 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.3531 | 0.5511 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0078 | 0.1293 | 0.1272 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1134 | 0.1134 |
Loa Loa (eye worm) | hypothetical protein | 0.0071 | 0.116 | 0.116 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0078 | 0.1293 | 0.1272 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0024 | 0.017 | 0.0784 |
Loa Loa (eye worm) | thyroglobulin type-1 repeat family protein | 0.007 | 0.1134 | 0.1134 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0034 | 0.0381 | 0.0346 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0034 | 0.0381 | 0.0381 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0051 | 0.0724 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0724 | 0.0653 |
Entamoeba histolytica | macrophage migration inhibitory factor-like protein | 0.046 | 0.9324 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0219 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0444 | 0.0444 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0381 | 0.0381 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1134 | 0.1134 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 1 |
Loa Loa (eye worm) | Smad1 | 0.0023 | 0.0149 | 0.0149 |
Loa Loa (eye worm) | macrophage migration inhibitory factor | 0.046 | 0.9324 | 0.9324 |
Trichomonas vaginalis | esterase, putative | 0.0034 | 0.0381 | 0.028 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0051 | 0.0731 | 0.0899 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0289 | 0.0289 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0319 | 0.6377 | 0.6377 |
Schistosoma mansoni | hypothetical protein | 0.0019 | 0.0057 | 0.0032 |
Trichomonas vaginalis | conserved hypothetical protein | 0.046 | 0.9324 | 1 |
Echinococcus granulosus | Smad4 | 0.0023 | 0.0149 | 0.0113 |
Plasmodium falciparum | importin beta, putative | 0.003 | 0.0289 | 0.0181 |
Loa Loa (eye worm) | inositol-1 | 0.0038 | 0.0466 | 0.0466 |
Brugia malayi | MH2 domain containing protein | 0.0023 | 0.0149 | 0.0027 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0034 | 0.0382 | 0.0001 |
Schistosoma mansoni | survival motor neuron protein | 0.01 | 0.1769 | 0.2733 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0023 | 0.0149 | 0.0113 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0051 | 0.0724 | 0.069 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0056 | 0.0832 | 0.1255 |
Schistosoma mansoni | smad1 5 8 and | 0.0023 | 0.0149 | 0.0178 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0021 | 0.0094 | 0.009 |
Loa Loa (eye worm) | beta-lactamase | 0.0034 | 0.0381 | 0.0381 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0389 | 0.7831 | 0.7831 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0034 | 0.0381 | 0.028 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0724 | 0.0653 |
Mycobacterium leprae | Probable lipase LipE | 0.0034 | 0.0381 | 0.1479 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0034 | 0.0381 | 0.0543 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0054 | 0.0789 | 0.0755 |
Echinococcus multilocularis | smad | 0.0023 | 0.0149 | 0.0113 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0051 | 0.0724 | 0.069 |
Echinococcus multilocularis | Smad4 | 0.0023 | 0.0149 | 0.0113 |
Loa Loa (eye worm) | intermediate filament protein | 0.0057 | 0.0865 | 0.0865 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0492 | 1 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0057 | 0.0865 | 0.0831 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0034 | 0.0381 | 0.4292 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0141 | 0.2619 | 0.2527 |
Onchocerca volvulus | 0.0442 | 0.896 | 1 | |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0051 | 0.0724 | 1 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.003 | 0.0289 | 0.0181 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0057 | 0.0865 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0481 | 0.0481 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0078 | 0.1293 | 1 |
Brugia malayi | intermediate filament protein | 0.0057 | 0.0865 | 0.0751 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0034 | 0.0381 | 0.0543 |
Trypanosoma brucei | protein kinase, putative | 0.0051 | 0.0724 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0045 | 0.0596 | 0.0562 |
Brugia malayi | PHD-finger family protein | 0.0023 | 0.0139 | 0.0016 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0057 | 0.0865 | 0.0751 |
Onchocerca volvulus | 0.007 | 0.1134 | 0.0877 | |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0843 | 0.0843 |
Echinococcus multilocularis | geminin | 0.0184 | 0.3531 | 0.3507 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1134 | 0.1134 |
Onchocerca volvulus | 0.007 | 0.1134 | 0.0877 | |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.2459 | 0.2459 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0028 | 0.0241 | 0.0205 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0038 | 0.0466 | 0.0373 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0038 | 0.0466 | 0.0373 |
Schistosoma mansoni | hypothetical protein | 0.0045 | 0.0596 | 0.0883 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0056 | 0.0832 | 0.0798 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0022 | 0.0123 | 0.0087 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0038 | 0.0466 | 0.0373 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0724 | 0.0653 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0045 | 0.0596 | 0.0562 |
Onchocerca volvulus | 0.01 | 0.1769 | 0.1618 | |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0865 | 0.0865 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0141 | 0.2619 | 0.2527 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0051 | 0.0724 | 0.0653 |
Onchocerca volvulus | Huntingtin homolog | 0.0133 | 0.2459 | 0.2421 |
Onchocerca volvulus | 0.0056 | 0.0832 | 0.0526 | |
Echinococcus granulosus | smad | 0.0023 | 0.0149 | 0.0113 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.1683 | 0.1683 |
Schistosoma mansoni | smad1 5 8 and | 0.0023 | 0.0149 | 0.0178 |
Brugia malayi | Inositol-1 | 0.0038 | 0.0466 | 0.0347 |
Onchocerca volvulus | 0.0057 | 0.0865 | 0.0563 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0219 | 0.0219 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0031 | 0.0305 | 0.0305 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.01 | 0.1769 | 0.1666 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.1134 | 0.1134 |
Echinococcus granulosus | geminin | 0.0184 | 0.3531 | 0.3507 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0034 | 0.0381 | 0.028 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0241 | 0.0241 |
Loa Loa (eye worm) | hypothetical protein | 0.0133 | 0.2459 | 0.2459 |
Schistosoma mansoni | hypothetical protein | 0.0319 | 0.6377 | 1 |
Brugia malayi | MH1 domain containing protein | 0.0023 | 0.0149 | 0.0027 |
Schistosoma mansoni | smad | 0.0023 | 0.0149 | 0.0178 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0038 | 0.0466 | 0.0373 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0034 | 0.0381 | 0.028 |
Schistosoma mansoni | intermediate filament proteins | 0.0057 | 0.0865 | 0.1306 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 0.1261 |
Plasmodium vivax | hypothetical protein, conserved | 0.0034 | 0.0381 | 0.028 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0141 | 0.2619 | 0.2619 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0051 | 0.0731 | 0.0697 |
Trichomonas vaginalis | set domain proteins, putative | 0.0442 | 0.896 | 0.9605 |
Echinococcus multilocularis | lamin | 0.0057 | 0.0865 | 0.0831 |
Brugia malayi | beta-lactamase family protein | 0.0034 | 0.0381 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0381 | 0.0381 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0398 | 0.0398 |
Loa Loa (eye worm) | hypothetical protein | 0.0492 | 1 | 1 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0024 | 0.017 | 0.0051 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0051 | 0.0731 | 0.4744 |
Schistosoma mansoni | hypothetical protein | 0.0184 | 0.3531 | 0.5511 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0078 | 0.1293 | 0.1261 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0051 | 0.0724 | 0.0653 |
Schistosoma mansoni | ran | 0.0022 | 0.0123 | 0.0136 |
Trichomonas vaginalis | importin beta-1, putative | 0.0024 | 0.017 | 0.0051 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0038 | 0.0466 | 0.0431 |
Brugia malayi | Probable ClpP-like protease | 0.0078 | 0.1293 | 0.1185 |
Brugia malayi | Thyroglobulin type-1 repeat family protein | 0.007 | 0.1134 | 0.1023 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0023 | 0.0149 | 0.0113 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0022 | 0.0123 | 0.0087 |
Schistosoma mansoni | bromodomain containing protein | 0.0058 | 0.0877 | 0.1326 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0027 | 0.0223 | 0.0108 |
Schistosoma mansoni | hypothetical protein | 0.0096 | 0.1683 | 0.2597 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0051 | 0.0724 | 0.0653 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0051 | 0.0724 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0027 | 0.0223 | 0.0108 |
Brugia malayi | beta-lactamase | 0.0034 | 0.0381 | 0.0261 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0019 | 0.0057 | 0.0057 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.046 | 0.9324 | 1 |
Schistosoma mansoni | inositol monophosphatase | 0.0038 | 0.0466 | 0.0677 |
Leishmania major | hypothetical protein, conserved | 0.0034 | 0.0381 | 0.028 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Inhibition (binding) | = 1 % | Inhibitory activity against c-src tyrosine kinase at 50 uM | ChEMBL. | No reference |
Inhibition (binding) | = 1 % | Inhibitory activity against c-src tyrosine kinase at 50 uM | ChEMBL. | No reference |
Inhibition (binding) | = 10 % | Inhibitory activity against fibroblast growth factor receptor (FGFr) at 50 uM | ChEMBL. | No reference |
Inhibition (binding) | = 10 % | Inhibitory activity against platelet-derived growth factor receptor (PDGFr) at 50 uM | ChEMBL. | No reference |
Inhibition (binding) | = 10 % | Inhibitory activity against fibroblast growth factor receptor (FGFr) at 50 uM | ChEMBL. | No reference |
Inhibition (binding) | = 10 % | Inhibitory activity against platelet-derived growth factor receptor (PDGFr) at 50 uM | ChEMBL. | No reference |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.