Detailed information for compound 1807562

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 269.179 | Formula: C11H6F3N3O2
  • H donors: 0 H acceptors: 3 LogP: 2.4 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C#CCn1c2ccc(cc2nc1C(F)(F)F)[N+](=O)[O-]
  • InChi: 1S/C11H6F3N3O2/c1-2-5-16-9-4-3-7(17(18)19)6-8(9)15-10(16)11(12,13)14/h1,3-4,6H,5H2
  • InChiKey: KBQQFGRLBCERKK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Entamoeba histolytica protein kinase, putative 0.0053 0.0042 0.0445
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0118 0.0757
Giardia lamblia Kinase, CMGC CDK 0.0096 0.0135 0.1418
Echinococcus granulosus tyrosine kinase 0.0068 0.0075 0.0485
Entamoeba histolytica protein kinase, putative 0.0035 0.0005 0.005
Echinococcus multilocularis cyclin dependent kinase 1 0.0096 0.0135 0.0867
Echinococcus multilocularis roundabout 2 0.0036 0.0006 0.004
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0057 0.0363
Schistosoma mansoni protein kinase C mu 0.0088 0.0116 0.075
Entamoeba histolytica protein kinase, putative 0.0036 0.0007 0.007
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0053 0.0042 0.0151
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0153 0.0254 0.2658
Brugia malayi SH2 domain containing protein 0.0042 0.0019 0.011
Brugia malayi cell division control protein 2 homolog 0.0096 0.0135 0.0772
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Brugia malayi serine/threonine kinase 12 0.048 0.0948 0.544
Echinococcus granulosus TGF beta receptor type 1 0.0083 0.0108 0.0693
Echinococcus granulosus titin 0.0042 0.0019 0.0125
Echinococcus granulosus receptor type guanylyl cyclase 0.0072 0.0083 0.0534
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0072 0.0082 0.0473
Echinococcus granulosus Protein kinase C brain isozyme 0.0054 0.0046 0.0298
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0046 0.0029 0.0188
Echinococcus granulosus atrial natriuretic peptide receptor 0.0046 0.0029 0.0188
Echinococcus granulosus twitchin 0.0108 0.016 0.1033
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Brugia malayi casein kinase 1, delta 0.0053 0.0043 0.0244
Giardia lamblia Kinase, NEK 0.0112 0.0168 0.1769
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0091 0.0123 0.0792
Echinococcus granulosus fibroblast growth factor receptor 4 0.0115 0.0174 0.1123
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.008 0.01 0.0643
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Loa Loa (eye worm) CAMK protein kinase 0.0042 0.0019 0.0111
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0133 0.0212 0.1215
Schistosoma mansoni tyrosine kinase 0.0053 0.0044 0.028
Echinococcus granulosus glutamate receptor 2 0.0046 0.0029 0.0188
Schistosoma mansoni tyrosine kinase 0.0042 0.0019 0.0122
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0627
Entamoeba histolytica hypothetical protein 0.0046 0.0029 0.0307
Loa Loa (eye worm) hypothetical protein 0.0042 0.0019 0.011
Entamoeba histolytica protein kinase, putative 0.018 0.0312 0.3292
Echinococcus multilocularis twitchin 0.0039 0.0012 0.008
Echinococcus multilocularis raf serine:threonine protein kinase 0.0039 0.0013 0.0086
Leishmania major protein kinase, putative 0.0053 0.0042 0.031
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0036 0.0006 0.004
Echinococcus multilocularis calcium activated potassium channel 0.0046 0.0029 0.0185
Schistosoma mansoni tyrosine kinase 0.0078 0.0097 0.0625
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0115 0.0174 0.1123
Echinococcus multilocularis casein kinase I alpha 0.0053 0.0043 0.0274
Onchocerca volvulus 0.0042 0.0019 0.0093
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0153 0.1618
Echinococcus granulosus aurora kinase A 0.048 0.0948 0.6109
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0091 0.0123 0.0624
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0104 0.0151 0.0976
Brugia malayi SRC-1 0.008 0.01 0.0573
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0101 0.0144 0.0929
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0041 0.0017 0.011
Echinococcus granulosus metabotropic glutamate receptor 5 0.0046 0.0029 0.0188
Schistosoma mansoni tyrosine kinase 0.008 0.01 0.0642
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0126 0.0198 0.1276
Loa Loa (eye worm) hypothetical protein 0.0166 0.0283 0.1624
Schistosoma mansoni tyrosine kinase 0.008 0.01 0.0642
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0045 0.0027 0.0172
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0029 0.0184
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0163 0.0276 0.1585
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0147 0.0241 0.1556
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus multilocularis tyrosine protein kinase Srms 0.0068 0.0075 0.0485
Loa Loa (eye worm) hypothetical protein 0.0139 0.0226 0.1295
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0153 0.0254 0.2579
Echinococcus granulosus tyrosine protein kinase Lyn 0.0098 0.0139 0.0897
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0087 0.0115 0.0742
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0133 0.0212 0.2123
Loa Loa (eye worm) hypothetical protein 0.0109 0.0162 0.0929
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Loa Loa (eye worm) hypothetical protein 0.0073 0.0085 0.049
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0091 0.0123 0.0792
Toxoplasma gondii AGC kinase 0.0091 0.0123 0.0624
Schistosoma mansoni vesicular amine transporter 0.007 0.0079 0.0505
Echinococcus granulosus neuroglian 0.0036 0.0006 0.004
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0221 0.1427
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0163 0.0276 0.178
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0068 0.0076 0.0487
Leishmania major protein kinase A catalytic subunit 0.0091 0.0123 0.1178
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0091 0.0123 0.1178
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0046 0.0029 0.0164
Entamoeba histolytica protein kinase, putative 0.0052 0.004 0.0426
Echinococcus granulosus NDR protein kinase 0.0041 0.0017 0.011
Schistosoma mansoni tyrosine kinase 0.0058 0.0053 0.034
Schistosoma mansoni protein kinase 0.0288 0.054 0.3483
Echinococcus multilocularis neuroglian 0.009 0.0121 0.0779
Echinococcus multilocularis tyrosine protein kinase Blk 0.0068 0.0075 0.0485
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0275
Schistosoma mansoni nephrin 0.0093 0.0128 0.0823
Trypanosoma cruzi cdc2-related kinase 1 0.0096 0.0135 0.1391
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0039 0.0013 0.0086
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.048 0.0948 1
Echinococcus multilocularis serine:threonine protein kinase 0.0055 0.0048 0.0308
Toxoplasma gondii casein kinase I 0.0053 0.0043 0.0166
Giardia lamblia Kinase, CAMK CAMKL 0.0046 0.0028 0.0299
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.018 0.0312 0.1791
Schistosoma mansoni vav2 0.0033 0.0001 0.0007
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0083 0.0106 0.0686
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0228 0.0413 0.2663
Brugia malayi Protein kinase domain containing protein 0.0855 0.1743 1
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0117 0.0178 0.1148
Entamoeba histolytica protein kinase, putative 0.0105 0.0153 0.1618
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0292 0.1878
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0128 0.0201 0.2097
Echinococcus multilocularis cyclin dependent kinase 1 0.0096 0.0135 0.0867
Echinococcus granulosus protein kinase C gamma type 0.0041 0.0017 0.011
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0042 0.0019 0.0123
Trypanosoma brucei cdc2-related kinase 1 0.0096 0.0135 0.1297
Brugia malayi Protein kinase domain containing protein 0.049 0.0969 0.5564
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0088 0.0116 0.0668
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0017 0.0109
Onchocerca volvulus 0.0042 0.0019 0.0092
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Toxoplasma gondii AGC kinase 0.0041 0.0017 0.0021
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0106 0.0685
Echinococcus multilocularis serine:threonine protein kinase N2 0.0041 0.0017 0.011
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.4749 1 1
Entamoeba histolytica protein kinase, putative 0.018 0.0312 0.3292
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0091 0.0123 0.1273
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0017 0.0109
Brugia malayi Protein kinase domain containing protein 0.0041 0.0017 0.0098
Echinococcus multilocularis casein kinase I alpha 0.0053 0.0043 0.0274
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.019 0.0333 0.2144
Schistosoma mansoni serine/threonine protein kinase 0.048 0.0948 0.6109
Entamoeba histolytica protein kinase, putative 0.048 0.0948 1
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0151 0.0975
Echinococcus granulosus serine:threonine protein kinase 0.0055 0.0048 0.0308
Trypanosoma cruzi cdc2-related kinase 3 0.0096 0.0135 0.1391
Plasmodium falciparum calcium-dependent protein kinase 1 0.0053 0.0042 0.031
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0082 0.0105 0.0675
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0053 0.0042 0.0243
Echinococcus multilocularis serine:threonine protein kinase 38 0.0041 0.0017 0.011
Echinococcus multilocularis neuroglian 0.0036 0.0006 0.004
Echinococcus granulosus Vam6:Vps39 protein 0.0068 0.0076 0.0488
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0053 0.0043 0.0417
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0053 0.0042 0.0243
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0126 0.0198 0.1136
Giardia lamblia Kinase, CMGC GSK 0.0105 0.0153 0.1618
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0216 0.1393
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0153 0.0255 0.1644
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0104 0.0151 0.0976
Entamoeba histolytica p21-activated kinase 0.0036 0.0007 0.007
Loa Loa (eye worm) RGC/RGC protein kinase 0.0072 0.0083 0.0475
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.01 0.0643
Schistosoma mansoni protein kinase 0.0073 0.0085 0.0548
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0028 0.0161
Echinococcus granulosus dual specificity 0.018 0.0312 0.2012
Echinococcus multilocularis casein kinase I delta 0.0053 0.0043 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0135 0.0866
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Schistosoma mansoni tyrosine kinase 0.0143 0.0235 0.1511
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0046 0.0297
Echinococcus granulosus metabotropic glutamate receptor 2 0.0046 0.0029 0.0188
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0054 0.0046 0.0265
Echinococcus multilocularis tyrosine kinase 0.0042 0.0019 0.0123
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0137 0.0221 0.1427
Loa Loa (eye worm) TK/EGFR protein kinase 0.0078 0.0097 0.0557
Brugia malayi protein unc-22 0.0042 0.0019 0.0111
Trypanosoma brucei protein kinase, putative 0.0105 0.0153 0.1499
Schistosoma mansoni tyrosine kinase 0.0213 0.0382 0.2459
Entamoeba histolytica cell division protein kinase 2, putative 0.0096 0.0135 0.1418
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0073 0.0085 0.0489
Echinococcus granulosus tyrosine protein kinase Blk 0.0068 0.0075 0.0485
Trypanosoma brucei aurora B kinase 0.048 0.0948 1
Echinococcus multilocularis receptor type guanylyl cyclase 0.0072 0.0083 0.0534
Echinococcus granulosus activated cdc42 kinase 1 0.0175 0.0302 0.1949
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0043 0.0274
Schistosoma mansoni protein kinase 0.0153 0.0255 0.1643
Echinococcus multilocularis cyclin dependent kinase 9 0.0059 0.0057 0.0364
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0091 0.0123 0.0792
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.019 0.0333 0.1909
Plasmodium vivax casein kinase 1, putative 0.0053 0.0043 0.0153
Loa Loa (eye worm) AGC/AKT protein kinase 0.0044 0.0024 0.0136
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.008 0.01 0.0643
Echinococcus multilocularis cyclin dependent kinase 5 0.0096 0.0135 0.0867
Echinococcus multilocularis 0.0073 0.0085 0.0549
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0012 0.0079
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0078 0.0097 0.0625
Echinococcus multilocularis cyclin dependent kinase 7 0.0088 0.0118 0.0758
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0083 0.0107 0.0688
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0085 0.049
Echinococcus multilocularis epidermal growth factor receptor 0.0078 0.0097 0.0625
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0036 0.0204
Brugia malayi Protein kinase domain containing protein 0.0055 0.0048 0.0274
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0123 0.1301
Entamoeba histolytica cell division protein kinase 2, putative 0.0103 0.015 0.1578
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0054 0.0046 0.0262
Brugia malayi hypothetical protein 0.0055 0.0048 0.0275
Brugia malayi Protein kinase domain containing protein 0.0096 0.0135 0.0772
Plasmodium vivax glycogen synthase kinase 3, putative 0.0105 0.0153 0.1359
Schistosoma mansoni ATP-binding cassette transporter 0.0091 0.0123 0.0791
Onchocerca volvulus 0.0055 0.0048 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0135 0.0866
Onchocerca volvulus 0.0042 0.0019 0.0092
Echinococcus multilocularis serine:threonine protein kinase 0.0055 0.0048 0.0308
Loa Loa (eye worm) gastrulation defective protein 1 0.0118 0.0182 0.1044
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0068 0.0076 0.0487
Echinococcus granulosus epidermal growth factor receptor 0.0078 0.0097 0.0625
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0019 0.0111
Echinococcus granulosus cyclin dependent kinase 1 0.0096 0.0135 0.0867
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0167 0.1757
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0275
Brugia malayi putative serine/threonine kinase SADA gamma 0.0039 0.0013 0.0076
Loa Loa (eye worm) hypothetical protein 0.0068 0.0076 0.0434
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0036 0.0006 0.0039
Plasmodium falciparum protein kinase 5 0.0096 0.0135 0.1297
Brugia malayi casein kinase I 0.0053 0.0043 0.0244
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0046 0.0029 0.0188
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0221 0.1427
Echinococcus multilocularis glutamate receptor 2 0.0046 0.0029 0.0188
Loa Loa (eye worm) hypothetical protein 0.0125 0.0197 0.1128
Trypanosoma brucei rac serine-threonine kinase, putative 0.0044 0.0024 0.0111
Brugia malayi hypothetical protein 0.0046 0.0029 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0144 0.0929
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0765 0.1552 1
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0068 0.0076 0.0488
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.0243
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0135 0.0216 0.1241
Brugia malayi protein kinase C II. 0.0054 0.0046 0.0265
Echinococcus multilocularis mitogen activated protein kinase 11 0.0133 0.0212 0.1365
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0053 0.0042 0.0273
Echinococcus multilocularis tyrosine protein kinase shark 0.0042 0.0019 0.0123
Echinococcus multilocularis cyclin dependent kinase 9 0.0067 0.0072 0.0462
Echinococcus granulosus protein kinase c epsilon type 0.0054 0.0046 0.0298
Loa Loa (eye worm) hypothetical protein 0.015 0.0249 0.1427
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0053 0.0042 0.0164
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0153 0.0254 0.2579
Brugia malayi Protein kinase domain 0.0033 0 0.0001
Onchocerca volvulus Serine\/threonine kinase homolog 0.0104 0.0151 0.0853
Echinococcus granulosus cyclin dependent kinase 5 0.0096 0.0135 0.0867
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0033 0 0.0001
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0046 0.0029 0.0167
Plasmodium falciparum calcium-dependent protein kinase 4 0.0053 0.0042 0.031
Schistosoma mansoni atypical protein kinase C 0.0054 0.0046 0.0297
Mycobacterium ulcerans hypothetical protein 0.0871 0.1777 0.1414
Schistosoma mansoni hypothetical protein 0.0068 0.0076 0.0487
Loa Loa (eye worm) AGC/PKA protein kinase 0.0091 0.0123 0.0709
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0044 0.0024 0.0111
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0137 0.0221 0.1427
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0126 0.0198 0.1276
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Schistosoma mansoni protein kinase 0.0141 0.023 0.1483
Giardia lamblia Kinase, CMGC CDK 0.0096 0.0135 0.1418
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0217 0.1243
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0053 0.0042 0.0243
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0096 0.0135 0.0772
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0123 0.0192 0.1235
Loa Loa (eye worm) hypothetical protein 0.0161 0.0273 0.1565
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Echinococcus granulosus nmda type glutamate receptor 0.0323 0.0616 0.3967
Echinococcus multilocularis c src tyrosine kinase 0.0053 0.0044 0.0281
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0041 0.0017 0.011
Schistosoma mansoni cell adhesion molecule 0.0036 0.0006 0.0039
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.0312 0.3271
Trichomonas vaginalis AGC family protein kinase 0.0041 0.0017 0.0179
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0104 0.0151 0.1478
Trypanosoma cruzi cdc2-related kinase 1 0.0096 0.0135 0.1391
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0042 0.0272
Onchocerca volvulus 0.0125 0.0197 0.1112
Mycobacterium ulcerans hypothetical protein 0.0871 0.1777 0.1414
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0163 0.0276 0.1585
Onchocerca volvulus 0.0042 0.0019 0.0092
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0053 0.0042 0.0164
Brugia malayi cyclin-dependent kinase 9 0.0059 0.0057 0.0324
Echinococcus granulosus cyclin dependent kinase 0.0096 0.0135 0.0867
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0106 0.0685
Schistosoma mansoni tyrosine kinase 0.0053 0.0043 0.0279
Trichomonas vaginalis STE family protein kinase 0.0153 0.0254 0.2682
Echinococcus multilocularis aurora kinase A 0.048 0.0948 0.6109
Brugia malayi Protein kinase domain containing protein 0.0044 0.0024 0.0136
Schistosoma mansoni glutamate receptor AMPA 0.0091 0.0123 0.0791
Loa Loa (eye worm) TK protein kinase 0.0068 0.0075 0.0432
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0153 0.1618
Entamoeba histolytica PH domain containing protein kinase, putative 0.0094 0.013 0.1371
Mycobacterium tuberculosis Conserved hypothetical protein 0.0871 0.1777 0.1414
Loa Loa (eye worm) TK/FAK protein kinase 0.0257 0.0475 0.2725
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Loa Loa (eye worm) hypothetical protein 0.0097 0.0136 0.0782
Leishmania major casein kinase, putative 0.0053 0.0043 0.0313
Entamoeba histolytica casein kinase 1, putative 0.0053 0.0043 0.0448
Onchocerca volvulus 0.0053 0.0043 0.0227
Echinococcus multilocularis titin 0.0042 0.0019 0.0125
Echinococcus granulosus casein kinase i 0.0053 0.0043 0.0274
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0168 0.1769
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0091 0.0123 0.0792
Loa Loa (eye worm) hypothetical protein 0.0123 0.0191 0.1095
Brugia malayi Guanylyl cyclase protein 23 0.0072 0.0083 0.0475
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0288 0.054 0.3483
Echinococcus granulosus raf serine:threonine protein kinase 0.0039 0.0013 0.0086
Onchocerca volvulus 0.0046 0.0029 0.015
Loa Loa (eye worm) SRC-1 0.008 0.01 0.0573
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0046 0.0029 0.0167
Echinococcus multilocularis glutamate receptor 2 0.0091 0.0123 0.0792
Entamoeba histolytica protein kinase domain containing protein 0.048 0.0948 1
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0123 0.0795
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0117 0.0178 0.1023
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0046 0.0028 0.0161
Entamoeba histolytica serine/threonine protein kinase, putative 0.0039 0.0013 0.0139
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0039 0.0013 0.0076
Loa Loa (eye worm) hypothetical protein 0.0125 0.0197 0.1128
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0221 0.1427
Echinococcus multilocularis dual specificity 0.018 0.0312 0.2012
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Leishmania major protein kinase A catalytic subunit isoform 1 0.0091 0.0123 0.1178
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0201 0.2122
Echinococcus multilocularis TGF beta receptor type 1 0.0083 0.0108 0.0693
Loa Loa (eye worm) hypothetical protein 0.0072 0.0083 0.0475
Trypanosoma brucei polo-like protein kinase 0.0104 0.0151 0.1478
Entamoeba histolytica protein kinase domain containing protein 0.018 0.0312 0.3292
Giardia lamblia Kinase, CMGC GSK 0.0105 0.0153 0.1618
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0006 0.0036
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0025 0.0159
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0221 0.1427
Trichomonas vaginalis STE family protein kinase 0.0112 0.0168 0.1769
Loa Loa (eye worm) hypothetical protein 0.0068 0.0076 0.0434
Schistosoma mansoni microtubule-associated protein tau 0.0627 0.126 0.812
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.01 0.0643
Onchocerca volvulus 0.0105 0.0153 0.0864
Loa Loa (eye worm) TK/INSR protein kinase 0.0143 0.0235 0.1346
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0086
Loa Loa (eye worm) hypothetical protein 0.007 0.0079 0.0451
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0153 0.1618
Toxoplasma gondii aurora kinase 0.048 0.0948 0.5299
Trypanosoma brucei protein kinase, putative 0.0044 0.0024 0.0111
Entamoeba histolytica protein kinase, putative 0.0041 0.0017 0.0179
Brugia malayi SH2 domain containing protein 0.0042 0.0019 0.011
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0006 0.0036
Loa Loa (eye worm) hypothetical protein 0.0078 0.0095 0.0546
Echinococcus multilocularis cyclin dependent kinase 0.0096 0.0135 0.0867
Echinococcus multilocularis tyrosine protein kinase Abl 0.0125 0.0196 0.126
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0057 0.0595
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0105 0.0153 0.0989
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0115 0.0174 0.1123
Echinococcus multilocularis tyrosine protein kinase HCK 0.0052 0.004 0.0261
Brugia malayi metabotropic glutamate receptor type 2 0.0046 0.0029 0.0167
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0074 0.0087 0.0501
Brugia malayi Protein kinase domain containing protein 0.018 0.0312 0.1791
Echinococcus granulosus protein kinase 0.0073 0.0085 0.0549
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0068 0.0076 0.0767
Schistosoma mansoni protein kinase 0.0153 0.0255 0.1643
Brugia malayi Protein kinase domain containing protein 0.0163 0.0276 0.1585
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0029 0.0301
Giardia lamblia Kinase, NEK 0.0112 0.0168 0.1769
Plasmodium vivax protein kinase Crk2 0.0096 0.0135 0.1153
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0117 0.0178 0.1148
Echinococcus granulosus contactin 0.0036 0.0006 0.004
Trichomonas vaginalis STE family protein kinase 0.0153 0.0254 0.2682
Trichomonas vaginalis CK1 family protein kinase 0.0053 0.0043 0.0448
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0091 0.0123 0.1178
Brugia malayi Fibronectin type III domain containing protein 0.0073 0.0085 0.049
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0036 0.0006 0.004
Schistosoma mansoni glutamate receptor NMDA 0.0137 0.0221 0.1426
Echinococcus granulosus cyclin dependent kinase 7 0.0088 0.0118 0.0758
Brugia malayi Cam kinase protein 1 0.0053 0.0042 0.0243
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0036 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0085
Trypanosoma brucei casein kinase I, isoform 2 0.0053 0.0043 0.0313
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0123 0.0191 0.123
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0068 0.0076 0.0767
Schistosoma mansoni tyrosine kinase 0.0072 0.0083 0.0533
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0096 0.0135 0.0772
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.4749 1 1
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.0151 0.157
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0046 0.0297
Brugia malayi Protein kinase domain containing protein 0.0128 0.0201 0.1155
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0035 0.0005 0.005
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.4749 1 0.5
Plasmodium falciparum protein serine/threonine kinase-1 0.0128 0.0201 0.2011
Onchocerca volvulus 0.0042 0.0019 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0017 0.0109
Loa Loa (eye worm) hypothetical protein 0.0073 0.0085 0.049
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0135 0.1418
Leishmania major protein kinase, putative 0.048 0.0948 1
Loa Loa (eye worm) AGC/NDR protein kinase 0.0041 0.0017 0.0098
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0053 0.0044 0.028
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.017 0.0291 0.1878
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0072 0.0083 0.0458
Echinococcus granulosus protein kinase c iota type 0.0054 0.0046 0.0298
Brugia malayi Protein kinase domain containing protein 0.0046 0.0029 0.0164
Brugia malayi Protein kinase domain containing protein 0.0041 0.0017 0.0098
Echinococcus multilocularis death associated protein kinase 1 0.0755 0.1532 0.9875
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0053 0.0043 0.0244
Echinococcus granulosus tyrosine protein kinase HCK 0.0052 0.004 0.0261
Echinococcus granulosus dual specificity mitogen activated protein 0.0153 0.0254 0.1639
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0055 0.0048 0.0274
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Echinococcus granulosus serine:threonine protein kinase TAO1 0.019 0.0333 0.2144
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.048 0.0948 1
Loa Loa (eye worm) TK protein kinase 0.0052 0.004 0.0232
Echinococcus granulosus rho-associated protein kinase 1 0.0283 0.053 0.3414
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0053 0.0043 0.0244
Echinococcus multilocularis nmda type glutamate receptor 0.0323 0.0616 0.3967
Brugia malayi serine/threonine-protein kinase PAK 7 0.0184 0.0322 0.1845
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0085
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0135 0.0216 0.1241
Brugia malayi serine/threonine-protein kinase 6 0.048 0.0948 0.544
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0112 0.0168 0.1515
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0135 0.1418
Entamoeba histolytica serine/threonine protein kinase, putative 0.0104 0.0151 0.1597
Brugia malayi Protein kinase domain containing protein 0.0288 0.054 0.3102
Onchocerca volvulus 0.0072 0.0083 0.0458
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0068 0.0076 0.0667
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Echinococcus multilocularis roundabout 2 0.0105 0.0154 0.0993
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0068 0.0075 0.0485
Giardia lamblia Kinase, AGC AKT 0.0095 0.0131 0.1383
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0128 0.0201 0.1066
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0105 0.0153 0.0881
Brugia malayi Protein kinase domain containing protein 0.0175 0.0302 0.1735
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0091 0.0123 0.1178
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0042 0.0019 0.0111
Echinococcus multilocularis serine:threonine protein kinase N2 0.0041 0.0017 0.011
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0059 0.0057 0.0324
Schistosoma mansoni tyrosine kinase 0.0078 0.0097 0.0625
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0033 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0083 0.0107 0.0613
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0312 0.2011
Onchocerca volvulus 0.0072 0.0084 0.0463
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0033 0 0.0001
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0041 0.0017 0.0098
Echinococcus multilocularis casein kinase I alpha 0.0053 0.0043 0.0274
Echinococcus granulosus epidermal growth factor receptor 0.0078 0.0097 0.0625
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.084 0.1711 0.9822
Schistosoma mansoni protein kinase 0.048 0.0948 0.6109
Brugia malayi Protein kinase domain containing protein 0.009 0.0122 0.0699
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0128 0.0201 0.1155
Echinococcus granulosus casein kinase I alpha 0.0053 0.0043 0.0274
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Schistosoma mansoni tyrosine kinase 0.0164 0.0278 0.1789
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0174 0.0299 0.1928
Echinococcus granulosus hypothetical protein 0.0109 0.0162 0.1043
Schistosoma mansoni glutamate receptor kainate 0.0091 0.0123 0.0791
Echinococcus multilocularis nmda type glutamate receptor 0.0046 0.0029 0.0188
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0105 0.0153 0.0989
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0275
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0128 0.0201 0.2097
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0128 0.0201 0.2011
Schistosoma mansoni protein kinase 0.0053 0.0043 0.0274
Brugia malayi hypothetical protein 0.019 0.0333 0.1909
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0147 0.0241 0.1556
Echinococcus multilocularis calcium dependent protein kinase 0.0034 0.0003 0.0019
Schistosoma mansoni protein kinase 0.0044 0.0024 0.0152
Loa Loa (eye worm) hypothetical protein 0.007 0.0079 0.0455
Trypanosoma cruzi cdc2-related kinase 3 0.0096 0.0135 0.1391
Schistosoma mansoni tyrosine kinase 0.0053 0.0044 0.028
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0053 0.0042 0.031
Treponema pallidum licC protein (licC) 0.0871 0.1777 1
Entamoeba histolytica protein kinase, putative 0.0044 0.0024 0.0248
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0184 0.0322 0.2073
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0091 0.0123 0.1033
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0115 0.0174 0.1123
Echinococcus multilocularis basement membrane specific heparan sulfate 0.007 0.0079 0.0506
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.007 0.0079 0.0505
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.01 0.0143 0.0823
Brugia malayi Glutamate receptor 2 precursor 0.0091 0.0123 0.0705
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0039 0.0013 0.0108
Plasmodium falciparum calcium-dependent protein kinase 3 0.0053 0.0042 0.031
Loa Loa (eye worm) hypothetical protein 0.0036 0.0006 0.0036
Loa Loa (eye worm) hypothetical protein 0.007 0.0079 0.0451
Echinococcus granulosus roundabout 2 0.0036 0.0006 0.004
Echinococcus granulosus mitogen activated protein kinase 11 0.0133 0.0212 0.1365
Schistosoma mansoni tyrosine kinase 0.0072 0.0083 0.0533
Schistosoma mansoni serine/threonine kinase 0.0041 0.0017 0.0109
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0096 0.0135 0.0867
Entamoeba histolytica protein kinase , putative 0.048 0.0948 1
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0042 0.0445
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0276 0.178
Brugia malayi bone morphogenetic protein type 1 receptor 0.009 0.0122 0.0699
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.009 0.0122 0.0699
Onchocerca volvulus 0.0283 0.053 0.3028
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0133 0.0212 0.2123
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0091 0.0123 0.0792
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Entamoeba histolytica hypothetical protein 0.018 0.0312 0.3292
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0105 0.0153 0.1499
Brugia malayi Furin-like cysteine rich region family protein 0.0078 0.0097 0.0557
Echinococcus granulosus mitogen activated protein kinase 14 0.0133 0.0212 0.1365
Loa Loa (eye worm) AGC/PKN protein kinase 0.0041 0.0017 0.0098
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.0151 0.157
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0068 0.0076 0.0488
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0221 0.1425
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0088 0.0118 0.0675
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0083 0.0106 0.0686
Loa Loa (eye worm) hypothetical protein 0.0073 0.0085 0.049
Loa Loa (eye worm) glutamate receptor 1 0.0091 0.0123 0.0705
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0068 0.0075 0.0485
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0041 0.0017 0.011
Schistosoma mansoni tyrosine kinase 0.0254 0.0469 0.3023
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.018 0.0312 0.3197
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0025 0.0159
Onchocerca volvulus 0.0855 0.1743 1
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0096 0.0135 0.1297
Echinococcus granulosus activated cdc42 kinase 1 0.0175 0.0302 0.1949
Echinococcus granulosus tyrosine protein kinase shark 0.0042 0.0019 0.0123
Echinococcus multilocularis protein kinase shaggy 0.0105 0.0153 0.0989
Entamoeba histolytica protein kinase, putative 0.0044 0.0024 0.0248
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0074 0.0087 0.0501
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0137 0.0221 0.127
Plasmodium falciparum calcium-dependent protein kinase 2 0.0053 0.0042 0.031
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0024 0.0249
Brugia malayi Glutamate receptor 1 precursor 0.0091 0.0123 0.0705
Echinococcus multilocularis protein kinase c epsilon type 0.0054 0.0046 0.0298
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0053 0.0043 0.0244
Echinococcus granulosus nmda type glutamate receptor 0.0046 0.0029 0.0188
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0153 0.0254 0.1459
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0029 0.0184
Loa Loa (eye worm) hypothetical protein 0.0068 0.0076 0.0434
Schistosoma mansoni hypothetical protein 0.0091 0.0123 0.0791
Echinococcus multilocularis dual specificity protein kinase clk2 0.0128 0.0201 0.1297
Echinococcus multilocularis PAK box P21 Rho binding 0.0033 0 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0229 0.0416 0.2684
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0048 0.0503
Trichomonas vaginalis AGC family protein kinase 0.048 0.0948 1
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0091 0.0123 0.1178
Loa Loa (eye worm) AGC/PKA protein kinase 0.0091 0.0123 0.0709
Trichomonas vaginalis AGC family protein kinase 0.048 0.0948 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Schistosoma mansoni protein kinase 0.0153 0.0254 0.1638
Schistosoma mansoni tyrosine kinase 0.0053 0.0043 0.0279
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0095 0.0131 0.0753
Plasmodium falciparum NIMA related kinase 1 0.0112 0.0168 0.1652
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0085
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0083 0.0106 0.0686
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0091 0.0123 0.0709
Echinococcus multilocularis NMDA receptor 0.0091 0.0123 0.0792
Loa Loa (eye worm) glutamate receptor 2 0.0091 0.0123 0.0705
Brugia malayi serine/threonine-protein kinase plk-2 0.0104 0.0151 0.0869
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.0029 0.0167
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Trichomonas vaginalis AGC family protein kinase 0.0048 0.0032 0.0339
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0101 0.0144 0.0929
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Schistosoma mansoni kinase 0.0059 0.0057 0.0363
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0871 0.1777 0.1414
Onchocerca volvulus 0.0068 0.0076 0.0417
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0088 0.0116 0.0668
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0163 0.0276 0.157
Giardia lamblia Kinase, NEK 0.0112 0.0168 0.1769
Echinococcus granulosus microtubule associated protein 2 0.0627 0.126 0.812
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.01 0.0143 0.0823
Echinococcus granulosus tyrosine protein kinase Src42A 0.008 0.01 0.0643
Loa Loa (eye worm) AUR protein kinase 0.048 0.0948 0.544
Trichomonas vaginalis CK1 family protein kinase 0.0053 0.0043 0.0448
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0153 0.1618
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.0312 0.3271
Echinococcus multilocularis glutamate receptor 2 0.0137 0.0221 0.1427
Echinococcus multilocularis transfer RNA-Thr 0.0175 0.0302 0.1949
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0128 0.0201 0.2097
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0042 0.0019 0.0123
Brugia malayi Protein kinase domain containing protein 0.084 0.1711 0.9822
Loa Loa (eye worm) TK/ALK protein kinase 0.049 0.0969 0.5562
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0201 0.1296
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0083 0.0106 0.0686
Giardia lamblia Kinase, CK1 Casein kinase 0.0053 0.0043 0.0448
Echinococcus multilocularis protein KINase family member (kin 25) 0.0083 0.0107 0.0688
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0228 0.0413 0.2371
Schistosoma mansoni neuroglian 0.0036 0.0006 0.0039
Echinococcus granulosus tyrosine protein kinase Srms 0.0042 0.0019 0.0123
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0112 0.0168 0.0876
Schistosoma mansoni tyrosine kinase 0.0053 0.0043 0.0279
Brugia malayi intracellular kinase 0.0105 0.0153 0.0881
Trypanosoma cruzi aurora B kinase, putative 0.048 0.0948 1
Schistosoma mansoni kinase 0.0062 0.0062 0.0399
Loa Loa (eye worm) hypothetical protein 0.0102 0.0147 0.0844
Plasmodium falciparum protein kinase, putative 0.0044 0.0024 0.0111
Echinococcus multilocularis epidermal growth factor receptor 0.0078 0.0097 0.0625
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0083 0.0108 0.0693
Giardia lamblia Kinase, STE STE20 0.0153 0.0254 0.2682
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Loa Loa (eye worm) hypothetical protein 0.0069 0.0077 0.0442
Brugia malayi Protein kinase domain containing protein 0.0143 0.0235 0.1346
Echinococcus granulosus cyclin dependent kinase 19 0.0137 0.0221 0.1426
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.008 0.01 0.0643
Onchocerca volvulus Tyrosine kinase homolog 0.0327 0.0625 0.3574
Loa Loa (eye worm) hypothetical protein 0.0039 0.0013 0.0076
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0098 0.0138 0.1332
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0072 0.0083 0.0533
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0144 0.0929
Echinococcus granulosus casein kinase I delta 0.0053 0.0043 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0413 0.2662
Plasmodium falciparum casein kinase 1 0.0053 0.0043 0.0313
Entamoeba histolytica protein kinase, putative 0.0041 0.0017 0.0179
Trichomonas vaginalis STE family protein kinase 0.0153 0.0254 0.2682
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0041 0.0017 0.0098
Echinococcus multilocularis mitogen activated protein kinase 11 0.0133 0.0212 0.1365
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Brugia malayi hypothetical protein 0.0042 0.0019 0.011
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.017 0.0291 0.1878
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0091 0.0123 0.1273
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0046 0.0029 0.0188
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0006 0.0036
Schistosoma mansoni hypothetical protein 0.0034 0.0002 0.0014
Schistosoma mansoni metabotropic glutamate receptor 0.0046 0.0029 0.0187
Trichomonas vaginalis AGC family protein kinase 0.048 0.0948 1
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0174 0.0299 0.1928
Echinococcus multilocularis tyrosine protein kinase Src64B 0.008 0.01 0.0643
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0133 0.0212 0.2208
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Echinococcus multilocularis roundabout 2 0.0036 0.0006 0.004
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0123 0.0192 0.11
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0036 0.0006 0.004
Loa Loa (eye worm) hypothetical protein 0.0034 0.0002 0.0013
Loa Loa (eye worm) AUR protein kinase 0.048 0.0948 0.544
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0091 0.0123 0.1273
Trypanosoma cruzi extracellular receptor, putative 0.0046 0.0029 0.0275
Brugia malayi serine/threonine protein kinase 6 0.048 0.0948 0.544
Echinococcus granulosus titin 0.0042 0.0019 0.0125
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Echinococcus multilocularis rho associated protein kinase 0.0283 0.053 0.3414
Schistosoma mansoni cell adhesion molecule 0.0085 0.0112 0.0719
Echinococcus granulosus c-Jun N-terminal kinases 0.0228 0.0413 0.2663
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.01 0.0643
Plasmodium falciparum calcium-dependent protein kinase 5 0.0053 0.0042 0.031
Schistosoma mansoni glutamate receptor kainate 0.0091 0.0123 0.0791
Brugia malayi p70 ribosomal S6 kinase beta 0.0041 0.0017 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0033 0 0.0001
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Loa Loa (eye worm) TK/KIN16 protein kinase 0.039 0.0757 0.4342
Brugia malayi Hr1 repeat family protein 0.0041 0.0017 0.0098
Plasmodium vivax serine/threonine kinase-1, putative 0.0128 0.0201 0.1879
Loa Loa (eye worm) hypothetical protein 0.0175 0.0302 0.1735
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Loa Loa (eye worm) TK protein kinase 0.0135 0.0217 0.1243
Echinococcus granulosus serine:threonine protein kinase 12 B 0.048 0.0948 0.6109
Schistosoma mansoni serine/threonine kinase 0.0053 0.0044 0.0281
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0046 0.0029 0.0167
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0027 0.0153
Leishmania major protein kinase A catalytic subunit isoform 2 0.0091 0.0123 0.1178
Brugia malayi Protein kinase domain containing protein 0.0074 0.0087 0.0501
Echinococcus granulosus casein kinase I alpha 0.0053 0.0043 0.0274
Echinococcus granulosus tyrosine protein kinase Src64B 0.008 0.01 0.0643
Schistosoma mansoni tyrosine kinase 0.0115 0.0174 0.1122
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0135 0.1418
Giardia lamblia Kinase, AGC PKA 0.0091 0.0123 0.1301
Brugia malayi Receptor family ligand binding region containing protein 0.0072 0.0083 0.0475
Echinococcus granulosus roundabout 2 0.0105 0.0154 0.0993
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0104 0.0151 0.0869
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0163 0.0276 0.178
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0184 0.0322 0.1845
Brugia malayi protein-tyrosine kinase 0.0068 0.0075 0.0432
Mycobacterium tuberculosis Conserved hypothetical protein 0.0871 0.1777 0.1414
Loa Loa (eye worm) RGC/RGC protein kinase 0.0072 0.0083 0.0475
Brugia malayi hypothetical protein 0.0068 0.0076 0.0434
Echinococcus granulosus glutamate receptor subunit protein glur 0.0091 0.0123 0.0792
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0123 0.0192 0.1235
Loa Loa (eye worm) hypothetical protein 0.0065 0.0068 0.0391
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Brugia malayi Immunoglobulin I-set domain containing protein 0.039 0.0757 0.4342
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0178 0.1148
Echinococcus multilocularis casein kinase i 0.0053 0.0043 0.0274
Echinococcus granulosus defective proboscis extension response 0.007 0.0079 0.0506
Echinococcus multilocularis microtubule associated protein 2 0.0627 0.126 0.812
Brugia malayi Tyrosine-protein kinase abl-1 0.0125 0.0196 0.1122
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0045 0.0027 0.0172
Echinococcus granulosus casein kinase I alpha 0.0053 0.0043 0.0274
Loa Loa (eye worm) hypothetical protein 0.0072 0.0084 0.048
Brugia malayi Protein kinase domain containing protein 0.0137 0.0221 0.127
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Schistosoma mansoni metabotropic glutamate receptor 0.0046 0.0029 0.0187
Echinococcus multilocularis Immunoglobulin 0.007 0.0079 0.0506
Echinococcus granulosus activin receptor type 0.0375 0.0726 0.4679
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Schistosoma mansoni protein kinase 0.0153 0.0255 0.1643
Echinococcus granulosus cyclin dependent kinase 9 0.0059 0.0057 0.0364
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0627
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0201 0.1296
Brugia malayi Serine/threonine-protein kinase SULU 0.019 0.0333 0.1909
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0096 0.0135 0.0772
Trichomonas vaginalis CK1 family protein kinase 0.0053 0.0043 0.0448
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0033 0 0.0001
Echinococcus multilocularis tyrosine protein kinase Src42A 0.008 0.01 0.0643
Schistosoma mansoni protein kinase 0.0184 0.0322 0.2072
Schistosoma mansoni protein kinase 0.0083 0.0108 0.0693
Loa Loa (eye worm) hypothetical protein 0.0082 0.0105 0.0601
Trypanosoma brucei cdc2-related kinase 3 0.0096 0.0135 0.1297
Echinococcus granulosus serine:threonine protein kinase 0.0055 0.0048 0.0308
Loa Loa (eye worm) hypothetical protein 0.0439 0.0861 0.4942
Echinococcus granulosus glutamate NMDA receptor subunit 0.0765 0.1552 1
Leishmania major protein kinase, putative 0.0128 0.0201 0.2011
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0198 0.1275
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0118 0.0757
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0221 0.1427
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Loa Loa (eye worm) glutamate receptor 0.0046 0.0029 0.0167
Loa Loa (eye worm) hypothetical protein 0.0161 0.0273 0.1565
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0029 0.0184
Schistosoma mansoni tyrosine kinase 0.0143 0.0235 0.1511
Schistosoma mansoni rap gtpase-activating protein 0.0068 0.0076 0.0487
Plasmodium vivax calcium-dependent protein kinase, putative 0.0053 0.0042 0.0151
Echinococcus granulosus cyclin dependent kinase 9 0.0067 0.0072 0.0462
Echinococcus granulosus protein tyrosine kinase 0.0254 0.0469 0.3023
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.053 0.3414
Onchocerca volvulus 0.0042 0.0019 0.0092
Onchocerca volvulus 0.0042 0.0019 0.0092
Giardia lamblia Kinase, PLK 0.0104 0.0151 0.1597
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0123 0.0192 0.11
Entamoeba histolytica casein kinase, putative 0.0053 0.0043 0.0448
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0288 0.054 0.3483
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0126 0.0198 0.1136
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0096 0.0135 0.1297
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0053 0.0042 0.0151
Entamoeba histolytica protein kinase, putative 0.0053 0.0042 0.0445
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0044 0.0024 0.0218
Onchocerca volvulus 0.0282 0.0529 0.3022
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0041 0.0017 0.0098
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.01 0.0643
Leishmania major extracellular receptor, putative 0.0046 0.0029 0.017
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0039 0.025
Loa Loa (eye worm) hypothetical protein 0.0091 0.0123 0.0709
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0163 0.0276 0.1585
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Loa Loa (eye worm) RGC/RGC protein kinase 0.0072 0.0083 0.0475
Echinococcus granulosus calcium activated potassium channel 0.0046 0.0029 0.0185
Echinococcus granulosus tyrosine kinase 0.0042 0.0019 0.0123
Echinococcus multilocularis Immunoglobulin 0.007 0.0079 0.0506
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.048 0.0948 1
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0044 0.0024 0.0218
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0232 0.0423 0.5
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0128 0.0201 0.2011
Loa Loa (eye worm) IKK protein kinase 0.0855 0.1743 1
Echinococcus granulosus c src tyrosine kinase 0.0053 0.0044 0.0281
Brugia malayi Stress-activated protein kinase jnk-1 0.0228 0.0413 0.2371
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0871 0.1777 1
Schistosoma mansoni tyrosine kinase 0.0083 0.0107 0.0687
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0072 0.0084 0.0542
Toxoplasma gondii AGC kinase 0.0091 0.0123 0.0624
Plasmodium vivax serine/threonine protein kinase 6, putative 0.048 0.0948 1
Plasmodium falciparum glycogen synthase kinase 3 0.0105 0.0153 0.1499
Leishmania major protein kinase, putative 0.0128 0.0201 0.2011
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0072 0.0084 0.0542
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0184 0.0322 0.2073
Echinococcus granulosus tyrosine protein kinase ABL1 0.0229 0.0416 0.2684
Echinococcus multilocularis 0.0109 0.0162 0.1043
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0333 0.2143
Brugia malayi probable protein kinase 0.0141 0.023 0.1321
Echinococcus multilocularis activin receptor type 0.0375 0.0726 0.4679
Entamoeba histolytica protein kinase, putative 0.048 0.0948 1
Echinococcus granulosus TGF-beta receptor type-1 0.0083 0.0108 0.0693
Echinococcus granulosus tyrosine kinase 0.0072 0.0083 0.0534
Schistosoma mansoni titin 0.0042 0.0019 0.0124
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0153 0.0254 0.1459
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0039 0.0013 0.0108
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0033 0 0.0001
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0085
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0036 0.0006 0.004
Echinococcus granulosus dual specificity protein kinase clk2 0.0128 0.0201 0.1297
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0072 0.0082 0.0531
Schistosoma mansoni glutamate receptor NMDA 0.0765 0.1552 1
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0044 0.0024 0.0059
Schistosoma mansoni glutamate receptor AMPA 0.0091 0.0123 0.0791
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.017 0.0292 0.1673
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0323 0.0616 0.3967
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0041 0.0017 0.011
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.008 0.01 0.0643
Schistosoma mansoni protein kinase 0.0072 0.0083 0.0533
Echinococcus granulosus calcium dependent protein kinase 0.0034 0.0003 0.0019
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0105 0.0153 0.0881
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0074 0.0087 0.0501
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0123 0.0795
Echinococcus multilocularis insulin receptor 0.0143 0.0235 0.1512
Leishmania major protein kinase, putative 0.0044 0.0024 0.0111
Brugia malayi Protein kinase domain containing protein 0.017 0.0292 0.1673
Echinococcus multilocularis dual specificity mitogen activated protein 0.0153 0.0254 0.1639
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0105 0.0153 0.1591
Loa Loa (eye worm) hypothetical protein 0.0058 0.0053 0.0305
Schistosoma mansoni protein kinase 0.009 0.0122 0.0784
Echinococcus multilocularis serine threonine protein kinase 0.0041 0.0017 0.011
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Schistosoma mansoni tyrosine kinase 0.0078 0.0097 0.0625
Echinococcus granulosus roundabout 2 0.0036 0.0006 0.004
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0221 0.1427
Echinococcus granulosus serine:threonine kinase SAD 1 0.0039 0.0013 0.0086
Schistosoma mansoni tyrosine kinase 0.0039 0.0014 0.0092
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0053 0.0042 0.0151
Echinococcus granulosus casein kinase I delta 0.0053 0.0043 0.0274
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0091 0.0123 0.1273
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0019 0.0124
Entamoeba histolytica protein kinase, putative 0.0036 0.0007 0.007
Loa Loa (eye worm) TK/ABL protein kinase 0.0229 0.0416 0.239
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0046 0.0297
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0274
Brugia malayi Protein kinase domain containing protein 0.0257 0.0475 0.2725
Schistosoma mansoni glutamate receptor kainate 0.0091 0.0123 0.0791
Schistosoma mansoni cell adhesion molecule 0.0036 0.0006 0.0039
Chlamydia trachomatis glutamine binding protein 0.0232 0.0423 0.5
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0401 0.0782 0.5039
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0087 0.0115 0.0742
Onchocerca volvulus 0.0069 0.0077 0.0425
Schistosoma mansoni vam6/vps39 related 0.0068 0.0076 0.0487
Echinococcus multilocularis mitogen activated protein kinase 14 0.0133 0.0212 0.1365
Loa Loa (eye worm) hypothetical protein 0.0102 0.0147 0.0844
Echinococcus granulosus neuroglian 0.009 0.0121 0.0779
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0036 0.0006 0.004
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.01 0.0643
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0053 0.0042 0.0164
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0153 0.0255 0.1644
Echinococcus multilocularis mitogen activated protein kinase 14 0.0133 0.0212 0.1365
Brugia malayi Metabotropic glutamate receptor precursor. 0.0046 0.0029 0.0167
Giardia lamblia Kinase, CAMK CAMKL 0.0046 0.0028 0.0299
Giardia lamblia Kinase, CMGC CLK 0.0128 0.0201 0.2122
Echinococcus granulosus protein kinase shaggy 0.0105 0.0153 0.0989
Onchocerca volvulus 0.0264 0.049 0.2801
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0036 0.0204
Brugia malayi P38 map kinase family protein 2 0.0133 0.0212 0.1215
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0395 0.2548
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Brugia malayi Temporarily assigned gene name protein 59 0.0068 0.0076 0.0434
Loa Loa (eye worm) AUR protein kinase 0.048 0.0948 0.544
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0054 0.0046 0.0298
Plasmodium falciparum serine/threonine protein kinase, putative 0.048 0.0948 1
Echinococcus granulosus Immunoglobulin 0.007 0.0079 0.0506
Echinococcus multilocularis casein kinase I delta 0.0053 0.0043 0.0274
Brugia malayi Tyrosine-protein kinase abl-1 0.0116 0.0176 0.101
Echinococcus multilocularis tyrosine protein kinase Fgr 0.008 0.01 0.0643
Echinococcus granulosus glutamate receptor 2 0.0137 0.0221 0.1427
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.048 0.0948 0.6109
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Brugia malayi C1-like domain containing protein 0.0088 0.0116 0.0668
Echinococcus multilocularis activated cdc42 kinase 1 0.0175 0.0302 0.1949
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0105 0.0153 0.0794
Loa Loa (eye worm) hypothetical protein 0.0058 0.0053 0.0305
Trichomonas vaginalis AGC family protein kinase 0.0041 0.0017 0.0179
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0128 0.0201 0.2097
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0123 0.0795
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Brugia malayi cyclin-dependent kinase 7 homolog 0.0095 0.0133 0.0762
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0123 0.0192 0.11
Schistosoma mansoni protein kinase 0.0184 0.0322 0.2072
Loa Loa (eye worm) hypothetical protein 0.0125 0.0197 0.1128
Echinococcus multilocularis protein tyrosine kinase 0.0254 0.0469 0.3023
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0002 0.0013
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0288 0.054 0.3102
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.008 0.01 0.0643
Echinococcus multilocularis tyrosine kinase 0.0072 0.0083 0.0534
Loa Loa (eye worm) hypothetical protein 0.0049 0.0036 0.0204
Giardia lamblia Aurora kinase 0.048 0.0948 1
Brugia malayi protein C17H12.11 0.0055 0.0048 0.0275
Schistosoma mansoni nephrin 0.0036 0.0006 0.0039
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0042 0.0019 0.02
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0006 0.0036
Brugia malayi Protein kinase domain containing protein 0.0072 0.0082 0.0473
Echinococcus multilocularis cyclin dependent kinase 19 0.0137 0.0221 0.1426
Schistosoma mansoni Neurotrimin precursor (hNT) 0.007 0.0079 0.0505
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0105 0.0153 0.0988
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0133 0.0212 0.2208
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0091 0.0123 0.0792
Trichomonas vaginalis AGC family protein kinase 0.048 0.0948 1
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.018 0.0312 0.3197
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0046 0.0029 0.0167
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.01 0.0643
Echinococcus multilocularis protein kinase c iota type 0.0054 0.0046 0.0298
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0096 0.0135 0.0687
Brugia malayi hypothetical protein 0.0073 0.0085 0.049
Echinococcus granulosus insulin receptor 0.0143 0.0235 0.1512
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Entamoeba histolytica PH domain containing protein kinase, putative 0.0094 0.013 0.1371
Echinococcus granulosus serine:threonine protein kinase N2 0.0041 0.0017 0.011

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 700 ug ml-1 Antifungal activity against Candida albicans MTCC 227 after 24 hr by paper disk method ChEMBL. No reference
MIC (functional) = 750 ug ml-1 Antifungal activity against Saccharomyces cerevisiae MTCC 36 after 24 hr by paper disk method ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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