Detailed information for compound 1807562

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 269.179 | Formula: C11H6F3N3O2
  • H donors: 0 H acceptors: 3 LogP: 2.4 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: C#CCn1c2ccc(cc2nc1C(F)(F)F)[N+](=O)[O-]
  • InChi: 1S/C11H6F3N3O2/c1-2-5-16-9-4-3-7(17(18)19)6-8(9)15-10(16)11(12,13)14/h1,3-4,6H,5H2
  • InChiKey: KBQQFGRLBCERKK-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Brugia malayi Metabotropic glutamate receptor precursor. 0.0046 0.0029 0.0167
Echinococcus granulosus NDR protein kinase 0.0041 0.0017 0.011
Echinococcus granulosus proto oncogene serine:threonine protein kinase 0.0163 0.0276 0.178
Mycobacterium ulcerans hypothetical protein 0.0871 0.1777 0.1414
Echinococcus granulosus 5' AMP activated protein kinase catalytic 0.0126 0.0198 0.1276
Brugia malayi intracellular kinase 0.0105 0.0153 0.0881
Onchocerca volvulus 0.0283 0.053 0.3028
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0133 0.0212 0.2123
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0033 0 0.0001
Schistosoma mansoni serine/threonine kinase 0.0053 0.0044 0.0281
Schistosoma mansoni tyrosine kinase 0.0072 0.0083 0.0533
Schistosoma mansoni neuroglian 0.0036 0.0006 0.0039
Brugia malayi casein kinase 1, delta 0.0053 0.0043 0.0244
Loa Loa (eye worm) CMGC/CDK/CDK7 protein kinase 0.0088 0.0118 0.0675
Leishmania major protein kinase, putative 0.0044 0.0024 0.0111
Trichomonas vaginalis STE family protein kinase 0.0112 0.0168 0.1769
Brugia malayi Tyrosine-protein kinase abl-1 0.0116 0.0176 0.101
Schistosoma mansoni protein kinase 0.048 0.0948 0.6109
Schistosoma mansoni metabotropic glutamate receptor 0.0046 0.0029 0.0187
Brugia malayi EST embl|AI107989|AI107989 comes from the 3' UTR, putative 0.0126 0.0198 0.1136
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0053 0.0042 0.031
Echinococcus granulosus dual specificity mitogen activated protein 0.0153 0.0254 0.1639
Brugia malayi protein C17H12.11 0.0055 0.0048 0.0275
Brugia malayi Protein kinase domain containing protein 0.0143 0.0235 0.1346
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0053 0.0042 0.0243
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0053 0.0042 0.0164
Echinococcus multilocularis nmda type glutamate receptor 0.0323 0.0616 0.3967
Schistosoma mansoni hypothetical protein 0.0091 0.0123 0.0791
Schistosoma mansoni tyrosine kinase 0.0143 0.0235 0.1511
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0401 0.0782 0.5039
Brugia malayi serine/threonine kinase 12 0.048 0.0948 0.544
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0091 0.0123 0.1273
Echinococcus multilocularis proto oncogene serine:threonine protein kinase 0.0163 0.0276 0.178
Echinococcus granulosus protein kinase c epsilon type 0.0054 0.0046 0.0298
Leishmania major extracellular receptor, putative 0.0046 0.0029 0.017
Schistosoma mansoni tyrosine kinase 0.0053 0.0043 0.0279
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0053 0.0042 0.0151
Echinococcus multilocularis c src tyrosine kinase 0.0053 0.0044 0.0281
Echinococcus multilocularis 0.0073 0.0085 0.0549
Schistosoma mansoni serine/threonine protein kinase 0.018 0.0312 0.2011
Loa Loa (eye worm) IKK protein kinase 0.0855 0.1743 1
Trypanosoma brucei kinetoplastid kinetochore protein 19 0.0128 0.0201 0.2011
Echinococcus granulosus contactin 0.0036 0.0006 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0053 0.0042 0.0445
Echinococcus granulosus TGF-beta receptor type-1 0.0083 0.0108 0.0693
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Plasmodium falciparum casein kinase 1 0.0053 0.0043 0.0313
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus granulosus tyrosine protein kinase Src64B 0.008 0.01 0.0643
Echinococcus granulosus tyrosine kinase 0.0068 0.0075 0.0485
Schistosoma mansoni glutamate receptor AMPA 0.0091 0.0123 0.0791
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0036 0.0006 0.0036
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Brugia malayi Protein kinase domain containing protein 0.0046 0.0029 0.0164
Loa Loa (eye worm) STE/STE20/TAO protein kinase 0.019 0.0333 0.1909
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0106 0.0685
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Loa Loa (eye worm) hypothetical protein 0.0161 0.0273 0.1565
Trypanosoma cruzi 5'-AMP-activated protein kinase catalytic subunit alpha, putative 0.0039 0.0013 0.0108
Echinococcus multilocularis cyclin dependent kinase 19 0.0137 0.0221 0.1426
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0006 0.0036
Entamoeba histolytica protein kinase, putative 0.0105 0.0153 0.1618
Onchocerca volvulus 0.0046 0.0029 0.015
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 3 0.0091 0.0123 0.1273
Schistosoma mansoni serine/threonine protein kinase 0.0219 0.0395 0.2548
Brugia malayi Protein kinase domain containing protein 0.0074 0.0087 0.0501
Onchocerca volvulus Serine\/threonine kinase homolog 0.0104 0.0151 0.0853
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0083 0.0106 0.0686
Echinococcus granulosus serine:threonine protein kinase PAK 4 0.017 0.0291 0.1878
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Entamoeba histolytica protein kinase domain containing protein 0.018 0.0312 0.3292
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0045 0.0027 0.0172
Echinococcus granulosus roundabout 2 0.0105 0.0154 0.0993
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0053 0.0042 0.0243
Brugia malayi Calcitonin receptor-like protein seb-1 0.0049 0.0036 0.0204
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0144 0.0929
Toxoplasma gondii AGC kinase 0.0041 0.0017 0.0021
Loa Loa (eye worm) hypothetical protein 0.0068 0.0076 0.0434
Loa Loa (eye worm) CAMK/CAMKL/MELK protein kinase 0.0046 0.0029 0.0164
Entamoeba histolytica serine/threonine protein kinase, putative 0.0039 0.0013 0.0139
Echinococcus granulosus neuroglian 0.009 0.0121 0.0779
Loa Loa (eye worm) CMGC/CDK/CDK9 protein kinase 0.0059 0.0057 0.0324
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Loa Loa (eye worm) TK/ABL protein kinase 0.0229 0.0416 0.239
Echinococcus multilocularis raf serine:threonine protein kinase 0.0039 0.0013 0.0086
Giardia lamblia Kinase, CMGC CDK 0.0096 0.0135 0.1418
Plasmodium vivax serine/threonine protein kinase 6, putative 0.048 0.0948 1
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0044 0.0025 0.0159
Echinococcus granulosus tyrosine protein kinase Src42A 0.008 0.01 0.0643
Brugia malayi hypothetical protein 0.0073 0.0085 0.049
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0042 0.0019 0.0123
Mycobacterium tuberculosis Conserved hypothetical protein 0.0871 0.1777 0.1414
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0627
Echinococcus granulosus dual specificity protein kinase clk2 0.0128 0.0201 0.1297
Brugia malayi Immunoglobulin I-set domain containing protein 0.0046 0.0028 0.0161
Loa Loa (eye worm) hypothetical protein 0.0073 0.0085 0.049
Brugia malayi Dual specificity mitogen-activated protein kinase kinase mek-2 0.0153 0.0254 0.1459
Echinococcus multilocularis transfer RNA-Thr 0.0175 0.0302 0.1949
Loa Loa (eye worm) TKL/LRRK protein kinase 0.0072 0.0082 0.0473
Giardia lamblia Aurora kinase 0.048 0.0948 1
Schistosoma mansoni tyrosine kinase 0.0078 0.0097 0.0625
Echinococcus multilocularis tyrosine kinase 0.0072 0.0083 0.0534
Echinococcus multilocularis serine:threonine protein kinase 0.0055 0.0048 0.0308
Leishmania major protein kinase, putative 0.048 0.0948 1
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0201 0.1296
Echinococcus multilocularis serine:threonine protein kinase receptor R3 0.0083 0.0108 0.0693
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0221 0.1427
Giardia lamblia Kinase, CK1 Casein kinase 0.0053 0.0043 0.0448
Echinococcus granulosus roundabout 2 0.0036 0.0006 0.004
Trypanosoma brucei kinetoplastid kinetochore protein 10 0.0128 0.0201 0.2011
Loa Loa (eye worm) CAMK/CAMKL/CHK1 protein kinase 0.017 0.0292 0.1673
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0036 0.0006 0.004
Schistosoma mansoni vam6/vps39 related 0.0068 0.0076 0.0487
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0153 0.1618
Leishmania major protein kinase A catalytic subunit 0.0091 0.0123 0.1178
Loa Loa (eye worm) hypothetical protein 0.0109 0.0162 0.0929
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0128 0.0201 0.2097
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0036 0.0006 0.004
Echinococcus granulosus casein kinase I delta 0.0053 0.0043 0.0274
Schistosoma mansoni protein kinase 0.0044 0.0024 0.0152
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0006 0.0036
Loa Loa (eye worm) hypothetical protein 0.0123 0.0191 0.1095
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0083 0.0106 0.0686
Echinococcus granulosus hypothetical protein 0.0109 0.0162 0.1043
Wolbachia endosymbiont of Brugia malayi N-acetylglucosamine-1-phosphate uridyltransferase 0.4749 1 0.5
Echinococcus granulosus Immunoglobulin 0.007 0.0079 0.0506
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Loa Loa (eye worm) TK/FAK protein kinase 0.0257 0.0475 0.2725
Schistosoma mansoni protein kinase 0.0053 0.0043 0.0274
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Trypanosoma cruzi cdc2-related kinase 3 0.0096 0.0135 0.1391
Schistosoma mansoni serine/threonine protein kinase 0.0051 0.0039 0.025
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Entamoeba histolytica casein kinase 1, putative 0.0053 0.0043 0.0448
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.008 0.01 0.0643
Echinococcus multilocularis glutamate receptor 2 0.0046 0.0029 0.0188
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0068 0.0076 0.0487
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0135 0.0216 0.1241
Leishmania major protein kinase, putative 0.0128 0.0201 0.2011
Echinococcus multilocularis 0.0109 0.0162 0.1043
Schistosoma mansoni kinase 0.0062 0.0062 0.0399
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0137 0.0221 0.1427
Onchocerca volvulus 0.0282 0.0529 0.3022
Echinococcus multilocularis serine:threonine protein kinase N2 0.0041 0.0017 0.011
Loa Loa (eye worm) hypothetical protein 0.0068 0.0076 0.0434
Echinococcus granulosus ribosomal protein s6 kinase beta 1 0.0041 0.0017 0.011
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0049 0.0036 0.0204
Brugia malayi Protein kinase domain containing protein 0.0163 0.0276 0.1585
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0137 0.0221 0.1427
Plasmodium vivax glycogen synthase kinase 3, putative 0.0105 0.0153 0.1359
Echinococcus multilocularis calcium dependent protein kinase 0.0034 0.0003 0.0019
Echinococcus granulosus ribosomal protein S6 kinase alpha 3 0.0117 0.0178 0.1148
Trypanosoma brucei rac serine-threonine kinase, putative 0.0044 0.0024 0.0111
Schistosoma mansoni titin 0.0042 0.0019 0.0124
Schistosoma mansoni atypical protein kinase C 0.0054 0.0046 0.0297
Schistosoma mansoni tyrosine kinase 0.0083 0.0107 0.0687
Echinococcus multilocularis mitogen activated protein kinase 14 0.0133 0.0212 0.1365
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0055 0.0048 0.0503
Loa Loa (eye worm) AGC/PKA protein kinase 0.0091 0.0123 0.0709
Trichomonas vaginalis AGC family protein kinase 0.0091 0.0123 0.1301
Plasmodium falciparum protein kinase 5 0.0096 0.0135 0.1297
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0012 0.0079
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Trypanosoma cruzi casein kinase, delta isoform, putative 0.0053 0.0043 0.0417
Brugia malayi Immunoglobulin I-set domain containing protein 0.0036 0.0006 0.0036
Onchocerca volvulus 0.0042 0.0019 0.0092
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Trichomonas vaginalis AGC family protein kinase 0.0041 0.0017 0.0179
Schistosoma mansoni microtubule-associated protein tau 0.0627 0.126 0.812
Echinococcus granulosus titin 0.0042 0.0019 0.0125
Schistosoma mansoni tyrosine kinase 0.0053 0.0043 0.0279
Echinococcus granulosus protein kinase 0.0073 0.0085 0.0549
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0091 0.0123 0.0792
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0123 0.0192 0.11
Loa Loa (eye worm) hypothetical protein 0.0083 0.0107 0.0613
Echinococcus multilocularis protein kinase c iota type 0.0054 0.0046 0.0298
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0046 0.0029 0.0188
Schistosoma mansoni protein kinase 0.0184 0.0322 0.2072
Schistosoma mansoni tyrosine kinase 0.008 0.01 0.0642
Echinococcus granulosus serine:threonine protein kinase 12 B 0.048 0.0948 0.6109
Echinococcus multilocularis cyclin dependent kinase 9 0.0067 0.0072 0.0462
Toxoplasma gondii aurora kinase 0.048 0.0948 0.5299
Echinococcus multilocularis cyclin dependent kinase 0.0096 0.0135 0.0867
Brugia malayi Protein kinase domain containing protein 0.0855 0.1743 1
Brugia malayi Protein kinase domain containing protein 0.0072 0.0082 0.0473
Brugia malayi Protein kinase domain containing protein 0.0096 0.0135 0.0772
Loa Loa (eye worm) hypothetical protein 0.0072 0.0083 0.0475
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0105 0.0153 0.0881
Loa Loa (eye worm) hypothetical protein 0.015 0.0249 0.1427
Toxoplasma gondii protein kinase, cAMP-dependent, catalytic chain 0.0091 0.0123 0.0624
Trypanosoma brucei protein kinase A catalytic subunit, putative 0.0091 0.0123 0.1178
Echinococcus multilocularis atrial natriuretic peptide receptor 0.0046 0.0029 0.0188
Plasmodium vivax NIMA-related protein kinase (Pfnek-1), putative 0.0112 0.0168 0.1515
Giardia lamblia Kinase, AGC AKT 0.0095 0.0131 0.1383
Echinococcus multilocularis serine:threonine protein kinase 12 B 0.048 0.0948 0.6109
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0135 0.1418
Schistosoma mansoni tyrosine kinase 0.0039 0.0014 0.0092
Echinococcus multilocularis tyrosine protein kinase Src64B 0.008 0.01 0.0643
Toxoplasma gondii eukaryotic initiation factor-2B, gamma subunit, putative 0.0871 0.1777 1
Echinococcus multilocularis dual specificity protein kinase clk2 0.0128 0.0201 0.1297
Schistosoma mansoni glutamate receptor kainate 0.0091 0.0123 0.0791
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0133 0.0212 0.2123
Trypanosoma cruzi cdc2-related kinase 3 0.0096 0.0135 0.1391
Echinococcus granulosus defective proboscis extension response 0.007 0.0079 0.0506
Mycobacterium tuberculosis Conserved hypothetical protein 0.0871 0.1777 0.1414
Loa Loa (eye worm) RGC/RGC protein kinase 0.0072 0.0083 0.0475
Onchocerca volvulus 0.0068 0.0076 0.0417
Trichomonas vaginalis CMGC family protein kinase 0.0105 0.0153 0.1618
Echinococcus multilocularis cyclin dependent kinase 5 0.0096 0.0135 0.0867
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0128 0.0201 0.2097
Brugia malayi Protein kinase domain containing protein 0.0175 0.0302 0.1735
Echinococcus granulosus Vam6:Vps39 protein 0.0068 0.0076 0.0488
Schistosoma mansoni glutamate receptor AMPA 0.0091 0.0123 0.0791
Entamoeba histolytica PH domain containing protein kinase, putative 0.0094 0.013 0.1371
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0033 0 0.0001
Brugia malayi Protein kinase domain containing protein 0.0044 0.0024 0.0136
Loa Loa (eye worm) hypothetical protein 0.0073 0.0085 0.049
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.01 0.0643
Echinococcus multilocularis twitchin 0.0039 0.0012 0.008
Schistosoma mansoni nephrin 0.0093 0.0128 0.0823
Schistosoma mansoni tyrosine kinase 0.0164 0.0278 0.1789
Echinococcus multilocularis ribosomal protein S6 kinase alpha 3 0.0117 0.0178 0.1148
Schistosoma mansoni tyrosine kinase 0.0053 0.0044 0.028
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0123 0.0192 0.11
Loa Loa (eye worm) hypothetical protein 0.0139 0.0226 0.1295
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.01 0.0643
Treponema pallidum licC protein (licC) 0.0871 0.1777 1
Plasmodium falciparum cAMP-dependent protein kinase catalytic subunit 0.0091 0.0123 0.1178
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.008 0.01 0.0643
Brugia malayi Guanylyl cyclase protein 23 0.0072 0.0083 0.0475
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0053 0.0042 0.0273
Schistosoma mansoni protein kinase C mu 0.0088 0.0116 0.075
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0104 0.0151 0.0976
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0017 0.0109
Schistosoma mansoni tyrosine kinase 0.0058 0.0053 0.034
Schistosoma mansoni tyrosine kinase 0.0115 0.0174 0.1122
Brugia malayi hypothetical protein 0.019 0.0333 0.1909
Onchocerca volvulus 0.0072 0.0083 0.0458
Echinococcus granulosus rho-associated protein kinase 1 0.0283 0.053 0.3414
Echinococcus granulosus cyclin dependent kinase 9 0.0067 0.0072 0.0462
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0087 0.0115 0.0742
Echinococcus multilocularis NMDA receptor 0.0091 0.0123 0.0792
Entamoeba histolytica hypothetical protein 0.018 0.0312 0.3292
Schistosoma mansoni cell adhesion molecule 0.0085 0.0112 0.0719
Schistosoma mansoni serine/threonine protein kinase 0.0042 0.0019 0.0124
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Schistosoma mansoni serine/threonine protein kinase 0.0135 0.0216 0.1393
Echinococcus multilocularis casein kinase I alpha 0.0053 0.0043 0.0274
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0035 0.0005 0.005
Echinococcus granulosus insulin receptor 0.0143 0.0235 0.1512
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0074 0.0087 0.0501
Brugia malayi hypothetical protein 0.0046 0.0029 0.0167
Echinococcus granulosus casein kinase I alpha 0.0053 0.0043 0.0274
Brugia malayi Protein kinase domain containing protein 0.009 0.0122 0.0699
Echinococcus multilocularis casein kinase I alpha 0.0053 0.0043 0.0274
Echinococcus granulosus Ribosomal protein S6 kinase beta 2 0.0041 0.0017 0.011
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0221 0.1427
Brugia malayi Tyrosine-protein kinase abl-1 0.0125 0.0196 0.1122
Entamoeba histolytica protein kinase, putative 0.0053 0.0042 0.0445
Echinococcus multilocularis neuroglian 0.0036 0.0006 0.004
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Giardia lamblia Kinase, NEK 0.0112 0.0168 0.1769
Echinococcus multilocularis serine:threonine protein kinase MARK2 0.0083 0.0106 0.0686
Trypanosoma brucei CMGC/DYRK protein kinase, putative 0.018 0.0312 0.3197
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0046 0.0029 0.0167
Brugia malayi protein kinase C II. 0.0054 0.0046 0.0265
Onchocerca volvulus Tyrosine kinase homolog 0.0327 0.0625 0.3574
Echinococcus multilocularis G protein coupled receptor kinase 6 0.0123 0.0192 0.1235
Trypanosoma cruzi cdc2-related kinase 1 0.0096 0.0135 0.1391
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0046 0.0297
Brugia malayi Stress-activated protein kinase jnk-1 0.0228 0.0413 0.2371
Echinococcus multilocularis activated cdc42 kinase 1 0.0175 0.0302 0.1949
Toxoplasma gondii casein kinase I 0.0053 0.0043 0.0166
Echinococcus granulosus cyclin dependent kinase 19 0.0137 0.0221 0.1426
Onchocerca volvulus Serine\/threonine protein kinase homolog 0.0163 0.0276 0.157
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0135 0.1418
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0091 0.0123 0.0792
Trypanosoma cruzi kinetoplastid kinetochore protein 19, putative 0.0128 0.0201 0.2097
Echinococcus granulosus mitogen activated protein kinase kinase kinase 0.0288 0.054 0.3483
Echinococcus granulosus protein kinase c iota type 0.0054 0.0046 0.0298
Schistosoma mansoni protein kinase 0.0141 0.023 0.1483
Loa Loa (eye worm) CMGC/DYRK/DYRK1 protein kinase 0.018 0.0312 0.1791
Echinococcus multilocularis p21 activated protein kinase 1 Dpak1 0.0033 0 0.0001
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0068 0.0075 0.0485
Echinococcus granulosus glutamate receptor 2 0.0046 0.0029 0.0188
Echinococcus multilocularis Immunoglobulin 0.007 0.0079 0.0506
Echinococcus multilocularis rho associated protein kinase 0.0283 0.053 0.3414
Loa Loa (eye worm) hypothetical protein 0.0097 0.0136 0.0782
Schistosoma mansoni kinase 0.0059 0.0057 0.0363
Loa Loa (eye worm) hypothetical protein 0.007 0.0079 0.0455
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0087 0.0115 0.0742
Trichomonas vaginalis CK1 family protein kinase 0.0053 0.0043 0.0448
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0123 0.0795
Echinococcus multilocularis serine:threonine kinase SAD 1 0.0039 0.0013 0.0086
Echinococcus multilocularis casein kinase I alpha 0.0053 0.0043 0.0274
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0045 0.0027 0.0172
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0232 0.0423 0.5
Loa Loa (eye worm) glutamate receptor 0.0046 0.0029 0.0167
Plasmodium falciparum calcium-dependent protein kinase 2 0.0053 0.0042 0.031
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0184 0.0322 0.2073
Entamoeba histolytica cell division protein kinase 2, putative 0.0103 0.015 0.1578
Echinococcus multilocularis tyrosine protein kinase shark 0.0042 0.0019 0.0123
Brugia malayi Protein kinase domain containing protein 0.018 0.0312 0.1791
Brugia malayi Receptor family ligand binding region containing protein 0.0072 0.0083 0.0475
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0275
Echinococcus granulosus fibroblast growth factor receptor 4 0.0115 0.0174 0.1123
Echinococcus multilocularis ribosomal protein s6 kinase beta 1 0.0041 0.0017 0.011
Entamoeba histolytica protein kinase, putative 0.048 0.0948 1
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 2 0.0091 0.0123 0.1273
Schistosoma mansoni protein kinase 0.0153 0.0255 0.1643
Echinococcus multilocularis aurora kinase A 0.048 0.0948 0.6109
Schistosoma mansoni serine/threonine protein kinase 0.019 0.0333 0.2143
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0046 0.0029 0.0188
Echinococcus granulosus nmda type glutamate receptor 0.0323 0.0616 0.3967
Echinococcus granulosus serine:threonine protein kinase MARK2 0.0083 0.0106 0.0686
Schistosoma mansoni glycogen synthase kinase 3-related (gsk3) (cmgc group III) 0.0105 0.0153 0.0988
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0053 0.0042 0.0151
Echinococcus multilocularis dual specificity 0.018 0.0312 0.2012
Brugia malayi hypothetical protein 0.0042 0.0019 0.011
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0044 0.0024 0.0218
Brugia malayi Protein kinase domain containing protein 0.017 0.0292 0.1673
Entamoeba histolytica protein kinase, putative 0.048 0.0948 1
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Brugia malayi serine/threonine protein kinase 6 0.048 0.0948 0.544
Brugia malayi Protein kinase domain containing protein 0.0041 0.0017 0.0098
Schistosoma mansoni protein kinase 0.0072 0.0083 0.0533
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 1 0.0091 0.0123 0.1178
Schistosoma mansoni protein kinase 0.0153 0.0255 0.1643
Toxoplasma gondii cell-cycle-associated protein kinase GSK, putative 0.0105 0.0153 0.0794
Echinococcus granulosus cyclin dependent kinase 5 0.0096 0.0135 0.0867
Loa Loa (eye worm) hypothetical protein 0.007 0.0079 0.0451
Trichomonas vaginalis AGC family protein kinase 0.048 0.0948 1
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0046 0.0029 0.0167
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0053 0.0043 0.0244
Echinococcus multilocularis fibroblast growth factor receptor 4 0.0115 0.0174 0.1123
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0042 0.0019 0.0123
Echinococcus granulosus nmda type glutamate receptor 0.0046 0.0029 0.0188
Giardia lamblia Kinase, CAMK CAMKL 0.0046 0.0028 0.0299
Schistosoma mansoni serine/threonine protein kinase 0.0059 0.0057 0.0363
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Echinococcus multilocularis tyrosine protein kinase Src42A 0.008 0.01 0.0643
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Echinococcus multilocularis epidermal growth factor receptor 0.0078 0.0097 0.0625
Brugia malayi Immunoglobulin I-set domain containing protein 0.0073 0.0085 0.049
Echinococcus multilocularis c Jun NH2 terminal kinase 0.0228 0.0413 0.2663
Echinococcus granulosus casein kinase I delta 0.0053 0.0043 0.0274
Onchocerca volvulus 0.0855 0.1743 1
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0029 0.0184
Loa Loa (eye worm) CAMK/CAMKL/MARK protein kinase 0.0055 0.0048 0.0274
Trypanosoma brucei cAMP-dependent protein kinase catalytic subunit 2 0.0091 0.0123 0.1178
Brugia malayi serine/threonine-protein kinase 6 0.048 0.0948 0.544
Schistosoma mansoni serine/threonine protein kinase 0.017 0.0292 0.1878
Schistosoma mansoni tyrosine kinase 0.0042 0.0019 0.0122
Loa Loa (eye worm) STE/STE20/MSN protein kinase 0.0073 0.0085 0.0489
Loa Loa (eye worm) TK/INSR protein kinase 0.0143 0.0235 0.1346
Echinococcus granulosus epidermal growth factor receptor 0.0078 0.0097 0.0625
Onchocerca volvulus 0.0264 0.049 0.2801
Giardia lamblia Kinase, AGC PKA 0.0091 0.0123 0.1301
Schistosoma mansoni tyrosine kinase 0.008 0.01 0.0642
Echinococcus multilocularis mitogen activated protein kinase 11 0.0133 0.0212 0.1365
Echinococcus granulosus mitogen activated protein kinase 14 0.0133 0.0212 0.1365
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0044 0.0024 0.0111
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Loa Loa (eye worm) glutamate receptor 2 0.0091 0.0123 0.0705
Brugia malayi protein-tyrosine kinase 0.0068 0.0075 0.0432
Schistosoma mansoni glutamate receptor NMDA 0.0137 0.0221 0.1426
Echinococcus multilocularis Ribosomal protein S6 kinase beta 2 0.0041 0.0017 0.011
Echinococcus granulosus glutamate NMDA receptor subunit 0.0765 0.1552 1
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0765 0.1552 1
Schistosoma mansoni serine/threonine protein kinase 0.0163 0.0276 0.178
Echinococcus multilocularis epidermal growth factor receptor 0.0078 0.0097 0.0625
Schistosoma mansoni tyrosine kinase 0.0213 0.0382 0.2459
Echinococcus multilocularis mitogen activated protein kinase 11 0.0133 0.0212 0.1365
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0046 0.0028 0.0161
Echinococcus granulosus metabotropic glutamate receptor 2 0.0046 0.0029 0.0188
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0091 0.0123 0.0792
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Entamoeba histolytica protein kinase, putative 0.0052 0.004 0.0426
Trichomonas vaginalis CMGC family protein kinase 0.0096 0.0135 0.1418
Onchocerca volvulus 0.0072 0.0084 0.0463
Brugia malayi Immunoglobulin I-set domain containing protein 0.039 0.0757 0.4342
Giardia lamblia Kinase, CMGC GSK 0.0105 0.0153 0.1618
Brugia malayi probable protein kinase 0.0141 0.023 0.1321
Echinococcus multilocularis casein kinase I delta 0.0053 0.0043 0.0274
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus multilocularis basic fibroblast growth factor receptor 1 A 0.0115 0.0174 0.1123
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0221 0.1427
Echinococcus multilocularis dual specificity mitogen activated protein 0.0153 0.0254 0.1639
Loa Loa (eye worm) hypothetical protein 0.0078 0.0095 0.0546
Entamoeba histolytica PH domain containing protein kinase, putative 0.0094 0.013 0.1371
Trichomonas vaginalis AGC family protein kinase 0.0048 0.0032 0.0339
Schistosoma mansoni tyrosine kinase 0.0078 0.0097 0.0625
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0229 0.0416 0.2684
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0054 0.0046 0.0262
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0085
Echinococcus granulosus activin receptor type 0.0375 0.0726 0.4679
Loa Loa (eye worm) CMGC/CDK/CDK8 protein kinase 0.0137 0.0221 0.127
Schistosoma mansoni protein kinase 0.0083 0.0108 0.0693
Echinococcus multilocularis tyrosine protein kinase Srms 0.0068 0.0075 0.0485
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0096 0.0135 0.1297
Giardia lamblia Kinase, CMGC GSK 0.0105 0.0153 0.1618
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.0151 0.157
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Giardia lamblia Kinase, CMGC CDK 0.0096 0.0135 0.1418
Loa Loa (eye worm) STE/STE20/PAKB protein kinase 0.0184 0.0322 0.1845
Echinococcus multilocularis roundabout 2 0.0105 0.0154 0.0993
Entamoeba histolytica protein kinase domain containing protein 0.048 0.0948 1
Trypanosoma brucei casein kinase I, isoform 2 0.0053 0.0043 0.0313
Leishmania major protein kinase, putative 0.0128 0.0201 0.2011
Loa Loa (eye worm) AGC/DMPK/ROCK protein kinase 0.084 0.1711 0.9822
Echinococcus multilocularis casein kinase I delta 0.0053 0.0043 0.0274
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0017 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.0046 0.0029 0.0301
Trichomonas vaginalis STE family protein kinase 0.0153 0.0254 0.2682
Loa Loa (eye worm) STE/STE7/MEK1 protein kinase 0.0153 0.0254 0.1459
Loa Loa (eye worm) hypothetical protein 0.0065 0.0068 0.0391
Trichomonas vaginalis AGC family protein kinase 0.0041 0.0017 0.0179
Echinococcus multilocularis mitogen activated protein kinase kinase kinase 0.0288 0.054 0.3483
Brugia malayi Immunoglobulin I-set domain containing protein 0.0135 0.0217 0.1243
Echinococcus granulosus leucine rich repeat serine:threonine protein 0.0072 0.0083 0.0533
Brugia malayi serine/threonine-protein kinase PAK 7 0.0184 0.0322 0.1845
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Trypanosoma brucei mitogen-activated protein kinase kinase 5 0.0153 0.0254 0.2579
Echinococcus granulosus microtubule associated protein 2 0.0627 0.126 0.812
Brugia malayi hypothetical protein 0.0068 0.0076 0.0434
Plasmodium falciparum protein kinase, putative 0.0044 0.0024 0.0111
Echinococcus granulosus serine:threonine protein kinase TAO1 0.019 0.0333 0.2144
Echinococcus granulosus protein tyrosine kinase 0.0254 0.0469 0.3023
Loa Loa (eye worm) hypothetical protein 0.0058 0.0053 0.0305
Entamoeba histolytica hypothetical protein 0.0046 0.0029 0.0307
Brugia malayi SRC-1 0.008 0.01 0.0573
Brugia malayi SH2 domain containing protein 0.0042 0.0019 0.011
Schistosoma mansoni protein kinase 0.0073 0.0085 0.0548
Leishmania major protein kinase A catalytic subunit isoform 2 0.0091 0.0123 0.1178
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0091 0.0123 0.0792
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Echinococcus multilocularis receptor type guanylyl cyclase 0.0072 0.0083 0.0534
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0068 0.0076 0.0767
Entamoeba histolytica protein kinase, putative 0.018 0.0312 0.3292
Trypanosoma brucei protein kinase, putative 0.0044 0.0024 0.0111
Echinococcus granulosus activated cdc42 kinase 1 0.0175 0.0302 0.1949
Entamoeba histolytica cell division protein kinase 2, putative 0.0096 0.0135 0.1418
Brugia malayi bone morphogenetic protein type 1 receptor 0.009 0.0122 0.0699
Leishmania major protein kinase, putative 0.0053 0.0042 0.031
Trypanosoma cruzi glycogen synthase kinase 3, putative 0.0105 0.0153 0.1591
Loa Loa (eye worm) CK1/CK1/CK1-A protein kinase 0.0053 0.0043 0.0244
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0082 0.0105 0.0675
Loa Loa (eye worm) hypothetical protein 0.0125 0.0197 0.1128
Trypanosoma brucei aurora B kinase 0.048 0.0948 1
Echinococcus multilocularis calcium activated potassium channel 0.0046 0.0029 0.0185
Trichomonas vaginalis CAMK family protein kinase 0.0061 0.006 0.0627
Echinococcus granulosus protein kinase shaggy 0.0105 0.0153 0.0989
Echinococcus granulosus serine:threonine protein kinase 0.0055 0.0048 0.0308
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Brugia malayi Receptor family ligand binding region containing protein 0.0046 0.0029 0.0167
Schistosoma mansoni Neurotrimin precursor (hNT) 0.007 0.0079 0.0505
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0174 0.0299 0.1928
Echinococcus multilocularis nmda type glutamate receptor 0.0046 0.0029 0.0188
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Loa Loa (eye worm) hypothetical protein 0.0072 0.0084 0.048
Loa Loa (eye worm) CAMK protein kinase 0.0042 0.0019 0.0111
Entamoeba histolytica protein kinase , putative 0.048 0.0948 1
Loa Loa (eye worm) SRC-1 0.008 0.01 0.0573
Echinococcus multilocularis glycogen synthase kinase 3 beta 0.0105 0.0153 0.0989
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine pyrophosphorylase GlmU 0.4749 1 1
Onchocerca volvulus 0.0042 0.0019 0.0092
Echinococcus multilocularis TGF beta receptor type 1 0.0083 0.0108 0.0693
Schistosoma mansoni serine/threonine protein kinase 0.0228 0.0413 0.2662
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0049 0.0036 0.0204
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0104 0.0151 0.0869
Schistosoma mansoni cell adhesion molecule 0.0036 0.0006 0.0039
Plasmodium vivax serine/threonine kinase-1, putative 0.0128 0.0201 0.1879
Entamoeba histolytica protein kinase, putative 0.0053 0.0042 0.0445
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0042 0.0019 0.02
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.0312 0.3271
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Trypanosoma brucei polo-like protein kinase 0.0104 0.0151 0.1478
Brugia malayi Glutamate receptor 2 precursor 0.0091 0.0123 0.0705
Loa Loa (eye worm) hypothetical protein 0.0069 0.0077 0.0442
Echinococcus multilocularis tyrosine kinase 0.0042 0.0019 0.0123
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0043 0.0274
Brugia malayi Protein kinase domain containing protein 0.0042 0.0019 0.011
Onchocerca volvulus 0.0125 0.0197 0.1112
Entamoeba histolytica protein kinase, putative 0.018 0.0312 0.3292
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0137 0.0221 0.1427
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0078 0.0097 0.0625
Trypanosoma cruzi CMGC/DYRK protein kinase, putative 0.018 0.0312 0.3271
Entamoeba histolytica protein kinase, putative 0.0041 0.0017 0.0179
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0123 0.0795
Brugia malayi hypothetical protein 0.0055 0.0048 0.0275
Schistosoma mansoni ATP-binding cassette transporter 0.0091 0.0123 0.0791
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0118 0.0757
Echinococcus granulosus epidermal growth factor receptor 0.0078 0.0097 0.0625
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.01 0.0143 0.0823
Schistosoma mansoni vesicular amine transporter 0.007 0.0079 0.0505
Onchocerca volvulus 0.0042 0.0019 0.0092
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0147 0.0241 0.1556
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0046 0.0297
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0163 0.0276 0.1585
Echinococcus multilocularis basement membrane specific heparan sulfate 0.007 0.0079 0.0506
Trichomonas vaginalis AGC family protein kinase 0.0112 0.0168 0.1769
Loa Loa (eye worm) RGC/RGC protein kinase 0.0072 0.0083 0.0475
Echinococcus multilocularis tyrosine protein kinase Fyn 0.008 0.01 0.0643
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Loa Loa (eye worm) gastrulation defective protein 1 0.0118 0.0182 0.1044
Schistosoma mansoni cell adhesion molecule 0.0036 0.0006 0.0039
Loa Loa (eye worm) AGC/RSK/RSK protein kinase 0.0117 0.0178 0.1023
Schistosoma mansoni serine/threonine protein kinase 0.0283 0.053 0.3414
Schistosoma mansoni serine/threonine protein kinase 0.0117 0.0178 0.1148
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.008 0.01 0.0643
Schistosoma mansoni serine/threonine protein kinase 0.0137 0.0221 0.1425
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0091 0.0123 0.0792
Echinococcus granulosus p21 activated protein kinase 1 Dpak1 0.0033 0 0.0001
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0053 0.0044 0.028
Schistosoma mansoni serine/threonine protein kinase 0.0101 0.0144 0.0929
Loa Loa (eye worm) TKL/STKR/TYPE2 protein kinase 0.0074 0.0087 0.0501
Onchocerca volvulus 0.0069 0.0077 0.0425
Schistosoma mansoni protein kinase 0.0153 0.0255 0.1643
Onchocerca volvulus 0.0042 0.0019 0.0093
Loa Loa (eye worm) hypothetical protein 0.0091 0.0123 0.0709
Brugia malayi Phorbol esters/diacylglycerol binding domain 0.0088 0.0116 0.0668
Echinococcus multilocularis neuroglian 0.009 0.0121 0.0779
Loa Loa (eye worm) TK/ROR protein kinase 0.0045 0.0027 0.0153
Leishmania major glycogen synthase kinase, putative;with=GeneDB:LinJ18_V3.0270 0.0105 0.0153 0.1499
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0275
Loa Loa (eye worm) AGC/DMPK/GEK protein kinase 0.0041 0.0017 0.0098
Echinococcus granulosus neuroglian 0.0036 0.0006 0.004
Echinococcus multilocularis glutamate receptor 2 0.0091 0.0123 0.0792
Echinococcus granulosus tyrosine protein kinase HCK 0.0052 0.004 0.0261
Echinococcus granulosus protein kinase C gamma type 0.0041 0.0017 0.011
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0135 0.0866
Echinococcus granulosus calcium dependent protein kinase 0.0034 0.0003 0.0019
Echinococcus multilocularis serine:threonine protein kinase 0.0055 0.0048 0.0308
Loa Loa (eye worm) AGC/PKN protein kinase 0.0041 0.0017 0.0098
Trypanosoma brucei cdc2-related kinase 1 0.0096 0.0135 0.1297
Echinococcus granulosus cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0096 0.0135 0.0687
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0133 0.0212 0.2208
Giardia lamblia Kinase, NEK 0.0112 0.0168 0.1769
Echinococcus multilocularis serine:threonine protein kinase PAK 3 0.0033 0 0.0001
Echinococcus granulosus calcium activated potassium channel 0.0046 0.0029 0.0185
Trichomonas vaginalis AGC family protein kinase 0.048 0.0948 1
Schistosoma mansoni protein kinase 0.0153 0.0254 0.1638
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0044 0.0024 0.0218
Loa Loa (eye worm) hypothetical protein 0.0042 0.0019 0.011
Echinococcus granulosus serine:threonine kinase SAD 1 0.0039 0.0013 0.0086
Plasmodium falciparum calcium-dependent protein kinase 5 0.0053 0.0042 0.031
Echinococcus granulosus basic fibroblast growth factor receptor 1 A 0.0115 0.0174 0.1123
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0091 0.0123 0.0792
Loa Loa (eye worm) hypothetical protein 0.0053 0.0042 0.0243
Entamoeba histolytica protein kinase, putative 0.0044 0.0024 0.0248
Echinococcus multilocularis tyrosine protein kinase Fgr 0.008 0.01 0.0643
Trypanosoma cruzi SNF1-related protein kinases, putative 0.0039 0.0013 0.0108
Echinococcus granulosus tyrosine kinase 0.0072 0.0083 0.0534
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0002 0.0013
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Plasmodium vivax casein kinase 1, putative 0.0053 0.0043 0.0153
Echinococcus granulosus glutamate receptor 2 0.0137 0.0221 0.1427
Trichomonas vaginalis CK1 family protein kinase 0.0053 0.0043 0.0448
Toxoplasma gondii AGC kinase 0.0091 0.0123 0.0624
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Echinococcus granulosus TGF beta receptor type 1 0.0083 0.0108 0.0693
Trichomonas vaginalis CAMK family protein kinase 0.0111 0.0167 0.1757
Loa Loa (eye worm) hypothetical protein 0.0049 0.0036 0.0204
Brugia malayi Protein kinase domain containing protein 0.0137 0.0221 0.127
Plasmodium falciparum NIMA related kinase 1 0.0112 0.0168 0.1652
Loa Loa (eye worm) CMGC/MAPK/JNK protein kinase 0.0228 0.0413 0.2371
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Schistosoma mansoni serine/threonine protein kinase 0.0054 0.0046 0.0297
Trichomonas vaginalis CMGC family protein kinase 0.0128 0.0201 0.2122
Loa Loa (eye worm) hypothetical protein 0.0175 0.0302 0.1735
Echinococcus multilocularis GTPase activating Rap:RanGAP domain 3 0.0068 0.0076 0.0488
Loa Loa (eye worm) metabotropic glutamate receptor 8 0.0046 0.0029 0.0167
Brugia malayi protein unc-22 0.0042 0.0019 0.0111
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.007 0.0079 0.0505
Echinococcus granulosus cyclin dependent kinase 7 0.0088 0.0118 0.0758
Toxoplasma gondii calcium dependent protein kinase CDPK8 0.0044 0.0024 0.0059
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0096 0.0135 0.1297
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0274
Echinococcus granulosus cyclin dependent kinase 1 0.0096 0.0135 0.0867
Schistosoma mansoni tyrosine kinase 0.0053 0.0044 0.028
Echinococcus multilocularis tyrosine protein kinase HCK 0.0052 0.004 0.0261
Loa Loa (eye worm) hypothetical protein 0.0036 0.0006 0.0036
Brugia malayi metabotropic glutamate receptor type 2 0.0046 0.0029 0.0167
Schistosoma mansoni tyrosine kinase 0.0254 0.0469 0.3023
Schistosoma mansoni mitogen-activated protein kinase kinase kinase 3 mapkkk3 mekk3 0.0068 0.0076 0.0487
Echinococcus granulosus activated cdc42 kinase 1 0.0175 0.0302 0.1949
Brugia malayi cyclin-dependent kinase 7 homolog 0.0095 0.0133 0.0762
Trichomonas vaginalis STE family protein kinase 0.0153 0.0254 0.2682
Leishmania major rac serine-threonine kinase, putative,protein kinase, putative 0.0098 0.0138 0.1332
Loa Loa (eye worm) CAMK/CAMKL/BRSK protein kinase 0.0039 0.0013 0.0076
Schistosoma mansoni hypothetical protein 0.0068 0.0076 0.0487
Brugia malayi Protein kinase domain containing protein 0.084 0.1711 0.9822
Schistosoma mansoni serine/threonine protein kinase 0.0041 0.0017 0.0109
Echinococcus multilocularis cyclin dependent kinase 7 0.0088 0.0118 0.0758
Schistosoma mansoni rap gtpase-activating protein 0.0068 0.0076 0.0487
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0053 0.0042 0.0164
Loa Loa (eye worm) AUR protein kinase 0.048 0.0948 0.544
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0096 0.0135 0.0867
Loa Loa (eye worm) hypothetical protein 0.0039 0.0013 0.0076
Echinococcus multilocularis serine:threonine protein kinase 38 0.0041 0.0017 0.011
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Toxoplasma gondii cell-cycle-associated protein kinase CLK, putative 0.0128 0.0201 0.1066
Loa Loa (eye worm) CMGC/CLK protein kinase 0.0128 0.0201 0.1155
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.008 0.01 0.0643
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Loa Loa (eye worm) hypothetical protein 0.007 0.0079 0.0451
Schistosoma mansoni serine/threonine protein kinase 0.0126 0.0198 0.1275
Loa Loa (eye worm) hypothetical protein 0.0058 0.0053 0.0305
Echinococcus granulosus tyrosine protein kinase Src42A 0.0044 0.0025 0.0159
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Echinococcus granulosus Protein kinase C brain isozyme 0.0054 0.0046 0.0298
Onchocerca volvulus 0.0042 0.0019 0.0092
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0323 0.0616 0.3967
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Echinococcus granulosus roundabout 2 0.0036 0.0006 0.004
Schistosoma mansoni serine/threonine protein kinase 0.048 0.0948 0.6109
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0036 0.0006 0.004
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0153 0.0255 0.1644
Giardia lamblia Kinase, PLK 0.0104 0.0151 0.1597
Trypanosoma brucei Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0068 0.0076 0.0667
Echinococcus multilocularis microtubule associated protein 2 0.0627 0.126 0.812
Schistosoma mansoni serine/threonine protein kinase 0.0104 0.0151 0.0975
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0053 0.0042 0.0164
Echinococcus multilocularis leucine rich repeat serine:threonine protein 0.0072 0.0082 0.0531
Echinococcus multilocularis tyrosine protein kinase Abl 0.0125 0.0196 0.126
Brugia malayi cyclin-dependent kinase 9 0.0059 0.0057 0.0324
Brugia malayi Serine/threonine-protein kinase SULU 0.019 0.0333 0.1909
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.0074 0.0087 0.0501
Leishmania major protein kinase A catalytic subunit isoform 1 0.0091 0.0123 0.1178
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Echinococcus granulosus twitchin 0.0108 0.016 0.1033
Loa Loa (eye worm) AUR protein kinase 0.048 0.0948 0.544
Loa Loa (eye worm) AGC/NDR protein kinase 0.0041 0.0017 0.0098
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0085
Echinococcus multilocularis cAMP dependent protein kinase catalytic subunit 0.0091 0.0123 0.0796
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0104 0.0151 0.1478
Entamoeba histolytica serine/threonine- protein kinase 6, putative 0.048 0.0948 1
Echinococcus multilocularis enhancer of mRNA decapping protein 4 0.0072 0.0084 0.0542
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0096 0.0135 0.0772
Echinococcus granulosus serine:threonine protein kinase 0.0055 0.0048 0.0308
Echinococcus multilocularis serine threonine protein kinase 0.0041 0.0017 0.011
Echinococcus multilocularis Protein kinase C, brain isozyme 0.0054 0.0046 0.0298
Entamoeba histolytica serine/threonine protein kinase, putative 0.0104 0.0151 0.1597
Echinococcus granulosus metabotropic glutamate receptor 5 0.0046 0.0029 0.0188
Schistosoma mansoni protein kinase 0.0184 0.0322 0.2072
Brugia malayi Furin-like cysteine rich region family protein 0.0078 0.0097 0.0557
Mycobacterium ulcerans hypothetical protein 0.0871 0.1777 0.1414
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.01 0.0143 0.0823
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Onchocerca volvulus 0.0105 0.0153 0.0864
Brugia malayi Protein kinase domain containing protein 0.0041 0.0017 0.0098
Echinococcus granulosus [G-protein-coupledreceptor] kinase 0.0123 0.0192 0.1235
Echinococcus granulosus casein kinase I alpha 0.0053 0.0043 0.0274
Echinococcus granulosus titin 0.0042 0.0019 0.0125
Loa Loa (eye worm) TK/KIN16 protein kinase 0.039 0.0757 0.4342
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0153 0.1618
Echinococcus multilocularis roundabout 2 0.0036 0.0006 0.004
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0104 0.0151 0.0976
Echinococcus granulosus glycogen synthase kinase 3 beta 0.0105 0.0153 0.0989
Loa Loa (eye worm) hypothetical protein 0.0439 0.0861 0.4942
Plasmodium falciparum calcium-dependent protein kinase 4 0.0053 0.0042 0.031
Echinococcus multilocularis PAK box P21 Rho binding 0.0033 0 0.0001
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Loa Loa (eye worm) AGC/PKC/ETA protein kinase 0.0054 0.0046 0.0265
Giardia lamblia Kinase, NEK 0.0112 0.0168 0.1769
Echinococcus granulosus GTPase activating Rap:RanGAP domain 3 0.0068 0.0076 0.0488
Brugia malayi Protein kinase domain 0.0033 0 0.0001
Echinococcus multilocularis cyclin dependent kinase 9 0.0059 0.0057 0.0364
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0053 0.0042 0.0273
Echinococcus granulosus cyclin dependent kinase 9 0.0059 0.0057 0.0364
Schistosoma mansoni tyrosine kinase 0.0053 0.0043 0.0279
Trypanosoma cruzi kinetoplastid kinetochore protein 10, putative 0.0128 0.0201 0.2097
Giardia lamblia Kinase, CAMK CAMKL 0.0046 0.0028 0.0299
Loa Loa (eye worm) hypothetical protein 0.0068 0.0076 0.0434
Loa Loa (eye worm) TKL/STKR/TYPE1 protein kinase 0.009 0.0122 0.0699
Echinococcus granulosus tyrosine protein kinase ABL1 0.0229 0.0416 0.2684
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Loa Loa (eye worm) G protein-coupled receptor kinase 1 0.0123 0.0192 0.11
Echinococcus granulosus cyclin dependent kinase 0.0096 0.0135 0.0867
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0085
Onchocerca volvulus 0.0042 0.0019 0.0092
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0029 0.0184
Loa Loa (eye worm) AGC/RSK/MSK protein kinase 0.0041 0.0017 0.0098
Echinococcus granulosus glutamate receptor subunit protein glur 0.0091 0.0123 0.0792
Loa Loa (eye worm) TK/EGFR protein kinase 0.0078 0.0097 0.0557
Echinococcus granulosus serine:threonine protein kinase mig 15 0.0123 0.0191 0.123
Echinococcus multilocularis cyclin dependent kinase 1 0.0096 0.0135 0.0867
Brugia malayi ribosomal protein S6 kinase alpha 3 0.0095 0.0131 0.0753
Leishmania major mitogen-activated protein kinase kinase 5, putative;with=GeneDB:LmxM36.0860 0.0153 0.0254 0.2579
Schistosoma mansoni vav2 0.0033 0.0001 0.0007
Plasmodium vivax calcium-dependent protein kinase, putative 0.0053 0.0042 0.0151
Chlamydia trachomatis glutamine binding protein 0.0232 0.0423 0.5
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0036 0.0006 0.0039
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0053 0.0042 0.0243
Echinococcus granulosus enhancer of mRNA decapping protein 4 0.0072 0.0084 0.0542
Trypanosoma cruzi polo-like protein kinase, putative 0.0104 0.0151 0.157
Loa Loa (eye worm) hypothetical protein 0.0125 0.0197 0.1128
Loa Loa (eye worm) CMGC/GSK protein kinase 0.0105 0.0153 0.0881
Schistosoma mansoni nephrin 0.0036 0.0006 0.0039
Plasmodium falciparum glycogen synthase kinase 3 0.0105 0.0153 0.1499
Trichomonas vaginalis AGC family protein kinase 0.048 0.0948 1
Echinococcus multilocularis glutamate receptor 2 0.0137 0.0221 0.1427
Schistosoma mansoni serine/threonine protein kinase 0.0083 0.0106 0.0685
Echinococcus multilocularis protein kinase c epsilon type 0.0054 0.0046 0.0298
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0042 0.0272
Echinococcus granulosus serine:threonine protein kinase N2 0.0041 0.0017 0.011
Loa Loa (eye worm) TK/FER protein kinase 0.0042 0.0019 0.011
Echinococcus granulosus casein kinase I alpha 0.0053 0.0043 0.0274
Entamoeba histolytica serine/threonine- protein kinase 6 , putative 0.048 0.0948 1
Brugia malayi Protein kinase domain containing protein 0.049 0.0969 0.5564
Echinococcus multilocularis cyclin dependent kinase 1 0.0096 0.0135 0.0867
Loa Loa (eye worm) AGC/AKT protein kinase 0.0044 0.0024 0.0136
Loa Loa (eye worm) hypothetical protein 0.0102 0.0147 0.0844
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Schistosoma mansoni hypothetical protein 0.0034 0.0002 0.0014
Echinococcus granulosus tyrosine protein kinase Srms 0.0042 0.0019 0.0123
Echinococcus granulosus aurora kinase A 0.048 0.0948 0.6109
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Loa Loa (eye worm) CAMK/CAMKL/AMPK protein kinase 0.0126 0.0198 0.1136
Loa Loa (eye worm) CAMK/PKD protein kinase 0.0088 0.0116 0.0668
Mycobacterium ulcerans bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 0.4749 1 1
Echinococcus multilocularis titin 0.0042 0.0019 0.0125
Toxoplasma gondii NIMA-related protein kinase NIMA1 0.0112 0.0168 0.0876
Entamoeba histolytica protein kinase domain containing protein 0.0105 0.0153 0.1618
Schistosoma mansoni protein kinase 0.0288 0.054 0.3483
Loa Loa (eye worm) AGC/RSK/P70 protein kinase 0.0041 0.0017 0.0098
Brugia malayi Protein kinase domain containing protein 0.0128 0.0201 0.1155
Brugia malayi Cam kinase protein 1 0.0053 0.0042 0.0243
Brugia malayi putative serine/threonine kinase SADA gamma 0.0039 0.0013 0.0076
Echinococcus multilocularis Immunoglobulin 0.007 0.0079 0.0506
Brugia malayi Protein kinase domain containing protein 0.0055 0.0048 0.0274
Echinococcus multilocularis roundabout 2 0.0036 0.0006 0.004
Trypanosoma brucei protein kinase, putative 0.0105 0.0153 0.1499
Schistosoma mansoni serine/threonine protein kinase 0.0046 0.0029 0.0184
Echinococcus multilocularis casein kinase i 0.0053 0.0043 0.0274
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Leishmania major casein kinase, putative 0.0053 0.0043 0.0313
Entamoeba histolytica serine/threonine protein kinase 6, putative 0.048 0.0948 1
Echinococcus granulosus tyrosine protein kinase Blk 0.0068 0.0075 0.0485
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0036 0.0006 0.004
Entamoeba histolytica protein kinase domain containing protein 0.0044 0.0024 0.0249
Echinococcus multilocularis mitogen activated protein kinase 14 0.0133 0.0212 0.1365
Echinococcus multilocularis death associated protein kinase 1 0.0755 0.1532 0.9875
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0042 0.0019 0.0111
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Loa Loa (eye worm) hypothetical protein 0.0073 0.0085 0.049
Loa Loa (eye worm) hypothetical protein 0.0166 0.0283 0.1624
Loa Loa (eye worm) hypothetical protein 0.0082 0.0105 0.0601
Loa Loa (eye worm) hypothetical protein 0.0102 0.0147 0.0844
Loa Loa (eye worm) hypothetical protein 0.0125 0.0197 0.1128
Schistosoma mansoni tyrosine kinase 0.0143 0.0235 0.1511
Brugia malayi Protein kinase domain containing protein 0.0257 0.0475 0.2725
Echinococcus granulosus dual specificity 0.018 0.0312 0.2012
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0221 0.1427
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0083 0.0107 0.0688
Echinococcus multilocularis serine:threonine protein kinase TAO1 0.019 0.0333 0.2144
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.01 0.0643
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0036 0.0006 0.004
Brugia malayi Protein kinase domain containing protein 0.0288 0.054 0.3102
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0153 0.0255 0.1644
Onchocerca volvulus 0.0053 0.0043 0.0227
Brugia malayi serine/threonine-protein kinase plk-2 0.0104 0.0151 0.0869
Echinococcus granulosus tyrosine protein kinase shark 0.0042 0.0019 0.0123
Entamoeba histolytica protein kinase, putative 0.0041 0.0017 0.0179
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0046 0.0029 0.0167
Echinococcus multilocularis serine:threonine protein kinase N2 0.0041 0.0017 0.011
Onchocerca volvulus 0.0055 0.0048 0.0257
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0123 0.0795
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0147 0.0241 0.1556
Loa Loa (eye worm) hypothetical protein 0.0055 0.0048 0.0275
Echinococcus granulosus receptor type guanylyl cyclase 0.0072 0.0083 0.0534
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Echinococcus multilocularis 5' AMP activated protein kinase catalytic 0.0126 0.0198 0.1276
Trichomonas vaginalis CK1 family protein kinase 0.0053 0.0043 0.0448
Schistosoma mansoni protein kinase 0.009 0.0122 0.0784
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0096 0.0135 0.0772
Trypanosoma cruzi casein kinase, putative 0.0053 0.0043 0.0417
Brugia malayi casein kinase I 0.0053 0.0043 0.0244
Echinococcus granulosus c-Jun N-terminal kinases 0.0228 0.0413 0.2663
Plasmodium vivax cAMP-dependent protein kinase catalytic subunit, putative 0.0091 0.0123 0.1033
Trypanosoma cruzi aurora B kinase, putative 0.048 0.0948 1
Loa Loa (eye worm) STE/STE20/KHS protein kinase 0.0288 0.054 0.3102
Loa Loa (eye worm) RGC/RGC protein kinase 0.0072 0.0083 0.0475
Echinococcus multilocularis serine:threonine protein kinase MRCK beta 0.0101 0.0144 0.0929
Schistosoma mansoni glutamate receptor kainate 0.0091 0.0123 0.0791
Leishmania major serine/threonine-protein kinase, putative,protein kinase, putative 0.018 0.0312 0.3197
Trypanosoma cruzi cdc2-related kinase 1 0.0096 0.0135 0.1391
Loa Loa (eye worm) AGC/PKA protein kinase 0.0091 0.0123 0.0709
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0068 0.0075 0.0485
Echinococcus granulosus serine:threonine protein kinase PAK 3 0.0033 0 0.0001
Brugia malayi cAMP-dependent protein kinase catalytic subunit, putative 0.0091 0.0123 0.0709
Loa Loa (eye worm) CK1/CK1/CK1-D protein kinase 0.0053 0.0043 0.0244
Plasmodium falciparum calcium-dependent protein kinase 1 0.0053 0.0042 0.031
Mycobacterium ulcerans molybdopterin-guanine dinucleotide biosynthesis protein A 0.0871 0.1777 0.1414
Echinococcus multilocularis insulin receptor 0.0143 0.0235 0.1512
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0096 0.0135 0.0772
Loa Loa (eye worm) TK protein kinase 0.0135 0.0217 0.1243
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.008 0.01 0.0643
Onchocerca volvulus 0.0042 0.0019 0.0092
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Schistosoma mansoni tyrosine kinase 0.0072 0.0083 0.0533
Echinococcus multilocularis activin receptor type 0.0375 0.0726 0.4679
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Plasmodium vivax protein kinase Crk2 0.0096 0.0135 0.1153
Plasmodium falciparum calcium-dependent protein kinase 3 0.0053 0.0042 0.031
Loa Loa (eye worm) TK protein kinase 0.0052 0.004 0.0232
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0085
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0133 0.0212 0.1215
Trypanosoma cruzi extracellular receptor, putative 0.0046 0.0029 0.0275
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0133 0.0212 0.2208
Loa Loa (eye worm) glutamate receptor 1 0.0091 0.0123 0.0705
Echinococcus granulosus Serine/threonine-protein kinase Genghis Khan 0.0101 0.0144 0.0929
Loa Loa (eye worm) TK/ALK protein kinase 0.049 0.0969 0.5562
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0184 0.0322 0.2073
Brugia malayi p70 ribosomal S6 kinase beta 0.0041 0.0017 0.0098
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0072 0.0083 0.0458
Echinococcus granulosus tyrosine kinase 0.0042 0.0019 0.0123
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0135 0.0216 0.1241
Giardia lamblia Kinase, CMGC CLK 0.0128 0.0201 0.2122
Loa Loa (eye worm) CAMK/PIM protein kinase 0.0163 0.0276 0.1585
Schistosoma mansoni glutamate receptor NMDA 0.0765 0.1552 1
Brugia malayi P38 map kinase family protein 2 0.0133 0.0212 0.1215
Trypanosoma brucei cdc2-related kinase 3 0.0096 0.0135 0.1297
Entamoeba histolytica p21-activated kinase 0.0036 0.0007 0.007
Entamoeba histolytica protein kinase, putative 0.0035 0.0005 0.005
Echinococcus granulosus c src tyrosine kinase 0.0053 0.0044 0.0281
Entamoeba histolytica casein kinase, putative 0.0053 0.0043 0.0448
Brugia malayi SH2 domain containing protein 0.0042 0.0019 0.011
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0137 0.0221 0.1427
Plasmodium falciparum protein serine/threonine kinase-1 0.0128 0.0201 0.2011
Trichomonas vaginalis CAMK family protein kinase 0.0104 0.0151 0.1597
Entamoeba histolytica protein kinase, putative 0.0044 0.0024 0.0248
Schistosoma mansoni serine/threonine protein kinase 0.0088 0.0118 0.0757
Trypanosoma cruzi cAMP-dependent protein kinase catalytic subunit 1 0.0091 0.0123 0.1273
Schistosoma mansoni serine/threonine kinase 0.0041 0.0017 0.0109
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Brugia malayi Glutamate receptor 1 precursor 0.0091 0.0123 0.0705
Brugia malayi Temporarily assigned gene name protein 59 0.0068 0.0076 0.0434
Echinococcus multilocularis protein KINase family member (kin 25) 0.0083 0.0107 0.0688
Schistosoma mansoni glutamate receptor kainate 0.0091 0.0123 0.0791
Echinococcus granulosus atrial natriuretic peptide receptor 0.0046 0.0029 0.0188
Schistosoma mansoni serine/threonine protein kinase 0.0039 0.0013 0.0086
Loa Loa (eye worm) hypothetical protein 0.0161 0.0273 0.1565
Loa Loa (eye worm) AUR protein kinase 0.048 0.0948 0.544
Echinococcus granulosus casein kinase i 0.0053 0.0043 0.0274
Trichomonas vaginalis AGC family protein kinase 0.048 0.0948 1
Brugia malayi Hr1 repeat family protein 0.0041 0.0017 0.0098
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Trichomonas vaginalis CAMK family protein kinase 0.0039 0.0013 0.0139
Echinococcus multilocularis tyrosine protein kinase Blk 0.0068 0.0075 0.0485
Entamoeba histolytica protein kinase, putative 0.0036 0.0007 0.007
Schistosoma mansoni serine/threonine protein kinase 0.0128 0.0201 0.1296
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0174 0.0299 0.1928
Plasmodium falciparum serine/threonine protein kinase, putative 0.048 0.0948 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0002 0.0013
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0053 0.0042 0.0151
Brugia malayi Immunoglobulin I-set domain containing protein 0.0042 0.0019 0.0111
Echinococcus granulosus mitogen activated protein kinase 11 0.0133 0.0212 0.1365
Schistosoma mansoni serine/threonine protein kinase 0.0096 0.0135 0.0866
Trypanosoma cruzi mitogen-activated protein kinase kinase 5 0.0153 0.0254 0.2658
Trichomonas vaginalis STE family protein kinase 0.0153 0.0254 0.2682
Echinococcus granulosus raf serine:threonine protein kinase 0.0039 0.0013 0.0086
Brugia malayi C1-like domain containing protein 0.0088 0.0116 0.0668
Echinococcus multilocularis serine:threonine protein kinase PAK 4 0.017 0.0291 0.1878
Toxoplasma gondii AGC kinase 0.0091 0.0123 0.0624
Schistosoma mansoni tyrosine kinase 0.0078 0.0097 0.0625
Brugia malayi Serine/threonine-protein kinase Pim-3 0.0163 0.0276 0.1585
Entamoeba histolytica protein kinase domain containing protein 0.0059 0.0057 0.0595
Giardia lamblia Kinase, STE STE20 0.0153 0.0254 0.2682
Trypanosoma cruzi Vacuolar sorting protein 39 domain 1/Vacuolar sorting protein 39 domain 2, putative 0.0068 0.0076 0.0767
Echinococcus multilocularis protein tyrosine kinase 0.0254 0.0469 0.3023
Echinococcus multilocularis protein kinase shaggy 0.0105 0.0153 0.0989
Loa Loa (eye worm) hypothetical protein 0.0046 0.0029 0.0167
Loa Loa (eye worm) TK protein kinase 0.0068 0.0075 0.0432
Echinococcus granulosus tyrosine protein kinase Lyn 0.0098 0.0139 0.0897
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.01 0.0643
Schistosoma mansoni metabotropic glutamate receptor 0.0046 0.0029 0.0187
Brugia malayi Fibronectin type III domain containing protein 0.0073 0.0085 0.049
Echinococcus granulosus tyrosine protein kinase Fyn 0.008 0.01 0.0643
Trichomonas vaginalis AGC family protein kinase 0.0044 0.0024 0.0248
Entamoeba histolytica protein kinase, putative 0.0036 0.0007 0.007
Brugia malayi cell division control protein 2 homolog 0.0096 0.0135 0.0772

Activities

Activity type Activity value Assay description Source Reference
MIC (functional) = 700 ug ml-1 Antifungal activity against Candida albicans MTCC 227 after 24 hr by paper disk method ChEMBL. No reference
MIC (functional) = 750 ug ml-1 Antifungal activity against Saccharomyces cerevisiae MTCC 36 after 24 hr by paper disk method ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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