Detailed information for compound 1812512

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 430.539 | Formula: C27H30N2O3
  • H donors: 0 H acceptors: 0 LogP: 5.52 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(ccc1OCCN1CCCC1)CC1ON=C(C1)c1cccc2c1cccc2
  • InChi: 1S/C27H30N2O3/c1-30-27-18-20(11-12-26(27)31-16-15-29-13-4-5-14-29)17-22-19-25(28-32-22)24-10-6-8-21-7-2-3-9-23(21)24/h2-3,6-12,18,22H,4-5,13-17,19H2,1H3
  • InChiKey: BHDKHHPSMJBNMA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Toxoplasma gondii microneme protein MIC4 0.0038 0.0178 0.049
Brugia malayi EGF-like domain containing protein 0.0033 0.0149 0.0312
Schistosoma mansoni transient receptor potential channel 0.007 0.0369 0.0411
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0015 0.003
Trichomonas vaginalis glucosylceramidase, putative 0.0803 0.4779 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.006 0.0124
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0015 0.0031
Loa Loa (eye worm) hypothetical protein 0.0036 0.0164 0.0342
Schistosoma mansoni slit 0.0033 0.0149 0.0162
Toxoplasma gondii PAN/Apple domain-containing protein 0.0038 0.0178 0.049
Trichomonas vaginalis glucosylceramidase, putative 0.0527 0.3118 0.6507
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0015 0.001
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0088 0.0137
Onchocerca volvulus 0.0038 0.0178 0.0527
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0033 0.0616
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0033 0.0546
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0033 0.0546
Schistosoma mansoni ran 0.0021 0.0073 0.0075
Brugia malayi Cadherin domain containing protein 0.0033 0.0149 0.0312
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0088 0.0137
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0803 0.4779 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0037 0.0028
Toxoplasma gondii microneme protein MIC17A 0.0038 0.0178 0.049
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0125 0.0134
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0033 0.0068
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0037 0.0028
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0015 0.001
Loa Loa (eye worm) Notch2 0.0033 0.0149 0.0311
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Brugia malayi Latrophilin receptor protein 2 0.0032 0.014 0.0294
Echinococcus granulosus neurogenic locus notch protein 4 0.0033 0.0149 0.0168
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0229
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Brugia malayi Calcium binding EGF domain containing protein 0.0033 0.0149 0.0312
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.003
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0085 0.0131
Schistosoma mansoni notch 0.0033 0.0149 0.0162
Echinococcus multilocularis fibropellin Ia 0.0033 0.0149 0.0148
Onchocerca volvulus 0.0038 0.0178 0.0527
Echinococcus granulosus glycoprotein Antigen 5 0.0029 0.0125 0.014
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0073 0.3053
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0015 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0527 0.3118 0.6507
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0014 0.0033 0.0546
Schistosoma mansoni hypothetical protein 0.0165 0.094 0.1059
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0015 0.0031
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Echinococcus granulosus protein jagged 1 0.0033 0.0149 0.0168
Schistosoma mansoni hypothetical protein 0.0032 0.014 0.0152
Echinococcus multilocularis microtubule associated protein 2 0.1474 0.8819 0.8819
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0015 0.0037 0.0071
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.014 0.0294
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0117 0.5801
Echinococcus granulosus TRP transient receptor potential channel 0.0039 0.0185 0.0209
Brugia malayi Trypsin-like protease protein 5 0.0029 0.0125 0.0261
Schistosoma mansoni hypothetical protein 0.0033 0.0149 0.0162
Echinococcus granulosus cpg binding protein 0.003 0.0126 0.0142
Brugia malayi steroid hormone receptor 0.0011 0.0015 0.0031
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0037 0.0834
Echinococcus granulosus neurogenic locus notch protein 0.0033 0.0149 0.0168
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0185 0.0387
Brugia malayi ecdysteroid receptor 0.0011 0.0015 0.0031
Echinococcus granulosus ATP dependent DNA helicase Q5 0.001 0.0006 0.0006
Onchocerca volvulus Glucosylceramidase homolog 0.0527 0.3118 1
Toxoplasma gondii kringle domain-containing protein 0.0035 0.0162 0.0443
Brugia malayi Protein kinase domain containing protein 0.0035 0.0162 0.0339
Loa Loa (eye worm) hypothetical protein 0.0029 0.0125 0.0259
Echinococcus granulosus laminin 0.0027 0.011 0.0124
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0237 1
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0033 0.0616
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0015 0.001
Onchocerca volvulus 0.0033 0.0149 0.0432
Onchocerca volvulus 0.0014 0.0033 0.0059
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0015 0.001
Toxoplasma gondii calcium binding egf domain-containing protein 0.0027 0.011 0.0296
Plasmodium vivax importin-beta 2, putative 0.0028 0.0117 0.6428
Echinococcus multilocularis enteropeptidase 0.0029 0.0125 0.0124
Echinococcus multilocularis slit 2 protein 0.0033 0.0149 0.0148
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0029 0.0125 0.0134
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0015 0.0031
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.003
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0036 0.0164 0.6617
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0033 0.0467
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0152 0.6071
Trichomonas vaginalis glucosylceramidase, putative 0.0803 0.4779 1
Brugia malayi Importin beta-1 subunit 0.0028 0.0117 0.0246
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0185 0.0341
Trichomonas vaginalis maltase-glucoamylase, putative 0.0015 0.0037 0.0028
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0185 0.7588
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0015 0.003
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0014 0.0033 0.0546
Echinococcus granulosus enteropeptidase 0.0029 0.0125 0.014
Loa Loa (eye worm) hypothetical protein 0.0032 0.014 0.0293
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0152 0.6071
Brugia malayi nuclear receptor NHR-88 0.0011 0.0015 0.0031
Onchocerca volvulus 0.0256 0.1491 0.4757
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0015 0.003
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0033 0.0616
Loa Loa (eye worm) hypothetical protein 0.0029 0.0125 0.0259
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.014 0.0293
Echinococcus multilocularis protein jagged 2 0.0033 0.0149 0.0148
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0014 0.0033 0.007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Loa Loa (eye worm) ATP-dependent DNA helicase 0.001 0.0006 0.0012
Onchocerca volvulus 0.0014 0.0033 0.0059
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0237 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0073 0.0082
Onchocerca volvulus 0.0028 0.0117 0.0328
Echinococcus multilocularis neurogenic locus notch protein 4 0.0033 0.0149 0.0148
Echinococcus granulosus neurogenic locus notch protein 0.0033 0.0149 0.0168
Schistosoma mansoni transient receptor potential channel 0.0106 0.0584 0.0656
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0162 0.8545
Echinococcus multilocularis cpg binding protein 0.003 0.0126 0.0126
Schistosoma mansoni transient receptor potential channel 4 0.0106 0.0584 0.0656
Loa Loa (eye worm) hypothetical protein 0.0048 0.0237 0.0494
Echinococcus granulosus short transient receptor potential channel 6 0.007 0.0369 0.0418
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0006 0.0013
Brugia malayi Trypsin family protein 0.0029 0.0125 0.0261
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0185 0.0341
Echinococcus granulosus snurportin 1 0.0299 0.1749 0.1983
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0037 0.0028
Toxoplasma gondii calcium binding egf domain-containing protein 0.0027 0.011 0.0296
Schistosoma mansoni ran 0.0021 0.0073 0.0075
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Trichomonas vaginalis glucosylceramidase, putative 0.0527 0.3118 0.6507
Loa Loa (eye worm) hypothetical protein 0.0028 0.0117 0.0244
Onchocerca volvulus 0.0033 0.0149 0.0432
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0185 0.0341
Echinococcus multilocularis snurportin 1 0.0299 0.1749 0.1748
Schistosoma mansoni alpha-glucosidase 0.0153 0.0867 0.0976
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0237 0.0496
Loa Loa (eye worm) hypothetical protein 0.0036 0.0164 0.0342
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Trypanosoma brucei glucosidase, putative 0.0039 0.0185 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.0178 0.0372
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0015 0.0016
Echinococcus multilocularis neurogenic locus notch protein 0.0033 0.0149 0.0148
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0125 0.0134
Loa Loa (eye worm) hypothetical protein 0.0038 0.0178 0.0372
Trichomonas vaginalis glucosylceramidase, putative 0.0527 0.3118 0.6507
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0015 0.0016
Brugia malayi nuclear hormone receptor 0.0011 0.0015 0.0031
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0068
Onchocerca volvulus 0.0038 0.0178 0.0527
Echinococcus granulosus bloom syndrome protein 0.0023 0.0088 0.0099
Echinococcus granulosus GPCR family 2 0.0032 0.014 0.0158
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0117 0.0316
Brugia malayi Muscle positioning protein 4 0.0033 0.0149 0.0312
Brugia malayi Cadherin domain containing protein 0.0033 0.0149 0.0312
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0048 0.0237 1
Echinococcus multilocularis laminin 0.0027 0.011 0.011
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0125 0.0134
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0185 0.0185
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0237 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0185 0.7588
Brugia malayi EGF-like domain containing protein 0.0033 0.0149 0.0312
Onchocerca volvulus 0.0033 0.0149 0.0432
Schistosoma mansoni acetyl-CoA synthetase 0.0014 0.0033 0.0031
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.014 0.0158
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0229
Schistosoma mansoni hypothetical protein 0.0033 0.0149 0.0162
Echinococcus multilocularis tissue type plasminogen activator 0.0035 0.0162 0.0161
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0048 0.0237 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0101 0.0555 0.1159
Loa Loa (eye worm) hypothetical protein 0.0048 0.0237 0.0494
Trichomonas vaginalis glucosylceramidase, putative 0.0803 0.4779 1
Schistosoma mansoni cpg binding protein 0.0028 0.0117 0.0125
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.003
Schistosoma mansoni transient receptor potential channel 0.007 0.0369 0.0411
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0088 0.0088
Echinococcus multilocularis neurogenic locus notch protein 0.0033 0.0149 0.0148
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0048 0.0237 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0014 0.0033 0.1709
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0015 0.0031
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0229
Onchocerca volvulus 0.0029 0.0125 0.0353
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Toxoplasma gondii PAN domain-containing protein 0.0038 0.0178 0.049
Onchocerca volvulus 0.0038 0.0178 0.0527
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0014 0.0033 0.0077
Echinococcus granulosus neural cadherin 0.0033 0.0149 0.0168
Giardia lamblia High cysteine protein 0.0033 0.0149 1
Schistosoma mansoni septate junction protein 0.0033 0.0149 0.0162
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0117 0.0243
Onchocerca volvulus 0.0029 0.0125 0.0353
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0185 0.0341
Echinococcus granulosus geminin 0.0165 0.094 0.1065
Brugia malayi Fibulin-1 precursor 0.0027 0.011 0.0231
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0185 0.7588
Echinococcus multilocularis neurogenic locus protein delta 0.0033 0.0149 0.0148
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0015 0.0016
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0015 0.0014
Schistosoma mansoni hypothetical protein 0.0165 0.094 0.1059
Loa Loa (eye worm) hypothetical protein 0.0036 0.0164 0.0342
Echinococcus multilocularis protein jagged 1 0.0033 0.0149 0.0148
Toxoplasma gondii microneme protein MIC17C 0.0038 0.0178 0.049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0015 0.003
Onchocerca volvulus Neurogenic locus notch homolog 0.0033 0.0149 0.0432
Schistosoma mansoni cpg binding protein 0.003 0.0126 0.0136
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Trichomonas vaginalis glucosylceramidase, putative 0.0555 0.3288 0.6866
Schistosoma mansoni hypothetical protein 0.0029 0.0125 0.0134
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0185 0.0341
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0237 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0073 0.3053
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Onchocerca volvulus 0.0014 0.0033 0.0059
Echinococcus granulosus tissue type plasminogen activator 0.0035 0.0162 0.0183
Schistosoma mansoni notch 0.0033 0.0149 0.0162
Schistosoma mansoni hypothetical protein 0.0033 0.0149 0.0162
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0015 0.001
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0152 0.6071
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0015 0.001
Trichomonas vaginalis ran, putative 0.0021 0.0073 0.0104
Schistosoma mansoni hypothetical protein 0.0299 0.1749 0.1977
Toxoplasma gondii PAN domain-containing protein 0.0593 0.3517 1
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0015 0.001
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0033 0.0021
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0033 0.0467
Leishmania major acetyl-CoA synthetase, putative 0.0014 0.0033 0.0467
Schistosoma mansoni hypothetical protein 0.0033 0.0149 0.0162
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0014 0.0033 0.0037
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0015 0.0016
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0229
Brugia malayi Trypsin family protein 0.0029 0.0125 0.0261
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0029 0.0125 0.014
Brugia malayi CXXC zinc finger family protein 0.0028 0.0117 0.0244
Echinococcus granulosus delta-like protein 1 0.0033 0.0149 0.0168
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0014 0.0033 0.0546
Leishmania major importin beta-1 subunit, putative 0.0023 0.0085 0.2908
Loa Loa (eye worm) hypothetical protein 0.0029 0.0125 0.0259
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0014 0.0033 0.0546
Brugia malayi hypothetical protein 0.0029 0.0125 0.0261
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0185 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0237 1
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0015 0.0031
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0178 0.0372
Echinococcus multilocularis transient receptor potential ion channel A 0.0102 0.0563 0.0562
Trichomonas vaginalis antibiotic synthetase, putative 0.0014 0.0033 0.0021
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0015 0.003
Loa Loa (eye worm) hypothetical protein 0.0029 0.0125 0.0259
Echinococcus multilocularis transient receptor potential gamma protein 0.0106 0.0584 0.0584
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.003
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.1015 0.1015
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0033 0.007
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0073 0.4214
Echinococcus granulosus Mastin 0.0029 0.0125 0.014
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0117 0.5801
Loa Loa (eye worm) hypothetical protein 0.0038 0.0178 0.0372
Loa Loa (eye worm) hypothetical protein 0.0069 0.0363 0.0758
Toxoplasma gondii PAN domain-containing protein 0.0593 0.3517 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0185 0.051
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0033 0.0616
Brugia malayi Glycosyl hydrolases family 31 protein 0.0015 0.0037 0.0077
Toxoplasma gondii PAN domain-containing protein 0.0038 0.0178 0.049
Schistosoma mansoni notch 0.0033 0.0149 0.0162
Echinococcus granulosus transient receptor potential ion channel A 0.0102 0.0563 0.0638
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0125 0.0134
Echinococcus multilocularis glycoprotein Antigen 5 0.0029 0.0125 0.0124
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0015 0.0014
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0085 0.3833
Brugia malayi EGF-like domain containing protein 0.0033 0.0149 0.0312
Loa Loa (eye worm) hypothetical protein 0.0036 0.0164 0.0342
Onchocerca volvulus 0.0014 0.0033 0.0059
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0803 0.4779 1
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0088 0.0185
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0015 0.0016
Mycobacterium ulcerans hypothetical protein 0.0029 0.0125 0.4482
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0037 0.0028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0015 0.003
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0014 0.0033 0.0068
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Schistosoma mansoni hypothetical protein 0.0029 0.0125 0.0134
Schistosoma mansoni laminin gamma-3 chain 0.0033 0.0149 0.0162
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0125 0.0134
Onchocerca volvulus 0.0033 0.0149 0.0432
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.014 0.0158
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0027 0.011 0.0229
Echinococcus granulosus transient receptor potential gamma protein 0.0106 0.0584 0.0662
Loa Loa (eye worm) hypothetical protein 0.0048 0.0237 0.0494
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Toxoplasma gondii EGF family domain-containing protein 0.0033 0.0149 0.0406
Onchocerca volvulus 0.0038 0.0178 0.0527
Toxoplasma gondii hypothetical protein 0.0038 0.0178 0.049
Onchocerca volvulus 0.0038 0.0178 0.0527
Loa Loa (eye worm) trypsin family protein 0.0029 0.0125 0.0259
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.003
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0237 0.0496
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Onchocerca volvulus 0.0103 0.0566 0.1775
Schistosoma mansoni notch 0.0033 0.0149 0.0162
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0016 0.0042 0.0102
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0117 0.0117
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0073 0.0151
Schistosoma mansoni microtubule-associated protein tau 0.1474 0.8819 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0029 0.0125 0.014
Schistosoma mansoni cell polarity protein 0.0033 0.0149 0.0162
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Loa Loa (eye worm) oxidoreductase 0.0014 0.0033 0.0068
Echinococcus multilocularis short transient receptor potential channel 6 0.007 0.0369 0.0368
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0015 0.0014
Brugia malayi Calcium binding EGF domain containing protein 0.0033 0.0149 0.0312
Echinococcus multilocularis short transient receptor potential channel 6 0.007 0.0369 0.0368
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0036 0.0164 0.6421
Echinococcus multilocularis lysosomal alpha glucosidase 0.0177 0.1015 0.1015
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0015 0.0016
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0014 0.0033 0.0033
Brugia malayi Calcitonin receptor-like protein seb-1 0.0101 0.0555 0.1161
Onchocerca volvulus 0.0038 0.0178 0.0527
Toxoplasma gondii hypothetical protein 0.0038 0.0178 0.049
Loa Loa (eye worm) hypothetical protein 0.0101 0.0555 0.1159
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0015 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0015 0.0014
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.001 0.0006 0.000000000074809
Loa Loa (eye worm) hypothetical protein 0.001 0.0006 0.0012
Echinococcus multilocularis dnaJ subfamily B 0.0398 0.2341 0.234
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0014 0.0033 0.0077
Brugia malayi latrophilin 2 splice variant baaae 0.0069 0.0363 0.0759
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0014 0.0033 0.0546
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0027 0.011 0.0231
Toxoplasma gondii PAN domain-containing protein 0.0038 0.0178 0.049
Toxoplasma gondii microneme protein MIC17B 0.0038 0.0178 0.049
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0015 0.003
Brugia malayi RNA, U transporter 1 0.008 0.0428 0.0896
Onchocerca volvulus 0.0029 0.0125 0.0353
Onchocerca volvulus Putative cubilin 0.0033 0.0149 0.0432
Schistosoma mansoni notch 0.0033 0.0149 0.0162
Entamoeba histolytica Ran family GTPase 0.0021 0.0073 0.2317
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0015 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0527 0.3118 0.6507
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Loa Loa (eye worm) hypothetical protein 0.0038 0.0178 0.0372
Echinococcus granulosus protein jagged 2 0.0033 0.0149 0.0168
Brugia malayi notch-like transmembrane receptor 0.0033 0.0149 0.0312
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Loa Loa (eye worm) hypothetical protein 0.0038 0.0178 0.0372
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0015 0.0014
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0033 0.0149 0.0162
Entamoeba histolytica acyl-coA synthetase, putative 0.0048 0.0237 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0048 0.0237 1
Echinococcus granulosus notch 0.0033 0.0149 0.0168
Echinococcus granulosus lysosomal alpha glucosidase 0.0177 0.1015 0.1151
Brugia malayi Glycosyl hydrolases family 31 protein 0.0177 0.1015 0.2125
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0015 0.0037 0.0633
Trichomonas vaginalis glucosylceramidase, putative 0.0803 0.4779 1
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0037 0.0028
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0048 0.0237 1
Brugia malayi Transient-receptor-potential like protein 0.0039 0.0185 0.0387
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0015 0.0014
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0035 0.0162 0.983
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0015 0.0031
Mycobacterium ulcerans hypothetical protein 0.0048 0.0237 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Brugia malayi Calcium binding EGF domain containing protein 0.0033 0.0149 0.0312
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0048 0.0237 1
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0015 0.001
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0015 0.0031
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0267 0.0742
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0085 0.0131
Echinococcus multilocularis neurogenic locus protein delta 0.0033 0.0149 0.0148
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0027 0.011 0.0229
Echinococcus granulosus neurogenic locus protein delta 0.0033 0.0149 0.0168
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0033 0.0149 0.0312
Echinococcus multilocularis Mastin 0.0029 0.0125 0.0124
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0033 0.007
Loa Loa (eye worm) notch protein 0.0033 0.0149 0.0311
Brugia malayi GCC2 and GCC3 family protein 0.0033 0.0149 0.0312
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Echinococcus granulosus dnaJ subfamily B 0.0398 0.2341 0.2654
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0014 0.0033 0.0467
Loa Loa (eye worm) hypothetical protein 0.0027 0.011 0.0229
Loa Loa (eye worm) hypothetical protein 0.0038 0.0178 0.0372
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0015 0.0016
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0033 0.0616
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.003
Loa Loa (eye worm) TK/ROR protein kinase 0.0035 0.0162 0.0337
Brugia malayi EGF-like domain containing protein 0.0033 0.0149 0.0312
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0177 0.1015 0.2124
Toxoplasma gondii propionate-CoA ligase 0.0014 0.0033 0.0077
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.003
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0015 0.0031
Leishmania major glycosyl hydrolase-like protein 0.0015 0.0037 0.0633
Loa Loa (eye worm) hypothetical protein 0.0036 0.0164 0.0342
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0015 0.0031
Brugia malayi EGF-like domain containing protein 0.0033 0.0149 0.0312
Schistosoma mansoni cpg binding protein 0.003 0.0126 0.0136
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0015 0.0031
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0027 0.011 0.0229
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0185 0.0341
Echinococcus granulosus importin subunit beta 1 0.0028 0.0117 0.0132
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0015 0.0037 0.0028
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0185 0.0341
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0027 0.011 0.0118
Schistosoma mansoni hypothetical protein 0.0398 0.2341 0.2649
Leishmania major hypothetical protein, conserved 0.0035 0.0162 0.6484
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0033 0.0546
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0016 0.0043 0.0753
Brugia malayi Trypsin family protein 0.0029 0.0125 0.0261
Schistosoma mansoni hypothetical protein 0.0035 0.0162 0.0176
Echinococcus multilocularis transmembrane protease serine 3 0.0029 0.0125 0.0124
Onchocerca volvulus 0.0038 0.0178 0.0527
Onchocerca volvulus 0.0029 0.0125 0.0353
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0237 1
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0178 0.0372
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Toxoplasma gondii subtilisin SUB12 0.0038 0.0178 0.049
Onchocerca volvulus 0.0033 0.0149 0.0432
Onchocerca volvulus 0.0048 0.0237 0.0716
Mycobacterium ulcerans acyl-CoA synthetase 0.0048 0.0237 1
Echinococcus granulosus transmembrane protease serine 3 0.0029 0.0125 0.014
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0015 0.0031
Onchocerca volvulus 0.0029 0.0125 0.0353
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0015 0.0037 0.0834
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0029 0.0125 0.0124
Entamoeba histolytica hypothetical protein 0.0023 0.0085 0.2908
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0015 0.0014
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0073 0.3053
Onchocerca volvulus 0.0035 0.0162 0.0474
Onchocerca volvulus 0.0038 0.0178 0.0527
Loa Loa (eye worm) RecQ helicase 0.0023 0.0088 0.0184
Echinococcus granulosus short transient receptor potential channel 6 0.007 0.0369 0.0418
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0178 0.0372
Trichomonas vaginalis glucosylceramidase, putative 0.0803 0.4779 1
Echinococcus granulosus Tolloid protein 1 0.0027 0.011 0.0124
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0073 0.3022
Toxoplasma gondii PAN domain-containing protein 0.0038 0.0178 0.049
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0125 0.0124
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0014 0.0033 0.007
Trichomonas vaginalis alpha-glucosidase, putative 0.0015 0.0037 0.0028
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0073 0.0189
Echinococcus granulosus protein jagged 1 0.0033 0.0149 0.0168
Schistosoma mansoni hypothetical protein 0.0032 0.014 0.0152
Loa Loa (eye worm) hypothetical protein 0.0039 0.0185 0.0386
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Echinococcus multilocularis geminin 0.0165 0.094 0.0939
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0085 0.0131
Echinococcus multilocularis GPCR, family 2 0.0032 0.014 0.014
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.0305 0.0339
Schistosoma mansoni importin beta-1 0.0028 0.0117 0.0126
Loa Loa (eye worm) hypothetical protein 0.0011 0.0015 0.003
Echinococcus multilocularis fibrillin 1 0.0027 0.011 0.011
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0185 1
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0015 0.003
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0029 0.0125 0.0261
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0015 0.001
Loa Loa (eye worm) hypothetical protein 0.0035 0.0162 0.0337
Echinococcus multilocularis fat cadherin tumor suppressor 0.0033 0.0149 0.0148
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0014 0.0033 0.0546
Echinococcus multilocularis neural cadherin 0.0033 0.0149 0.0148
Brugia malayi AMP-binding enzyme family protein 0.0048 0.0237 0.0496
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0015 0.0031
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0101 0.0555 0.1161
Schistosoma mansoni notch 0.0033 0.0149 0.0162
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0125 0.0134
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0185 0.0341
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.014 0.014
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Onchocerca volvulus Arrow homolog 0.0027 0.011 0.0307
Echinococcus multilocularis TRP (transient receptor potential) channel 0.0039 0.0185 0.0184
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0185 0.0209
Loa Loa (eye worm) hypothetical protein 0.0106 0.0584 0.1221
Echinococcus granulosus slit 2 protein 0.0033 0.0149 0.0168
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0015 0.001
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0299 0.1749 0.3659
Schistosoma mansoni alpha-glucosidase 0.0153 0.0867 0.0976
Brugia malayi EGF-like domain containing protein 0.0033 0.0149 0.0312
Trypanosoma brucei glycosyl hydrolase-like protein 0.0015 0.0037 0.0834
Echinococcus multilocularis protein jagged 1 0.0033 0.0149 0.0148
Echinococcus granulosus fibropellin Ia 0.0033 0.0149 0.0168
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0038 0.0178 0.049
Schistosoma mansoni alpha glucosidase 0.0039 0.0185 0.0203
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0014 0.0033 0.0546
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0073 0.0072
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.001 0.0006 0.0006
Entamoeba histolytica acyl-CoA synthetase, putative 0.0048 0.0237 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0059 0.006
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0033 0.0149 0.0432
Trichomonas vaginalis glucosylceramidase, putative 0.0527 0.3118 0.6507
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Brugia malayi Trypsin family protein 0.0029 0.0125 0.0261
Schistosoma mansoni egf-like domain protein 0.0027 0.011 0.0118
Schistosoma mansoni hypothetical protein 0.0033 0.0149 0.0162
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0178 0.0372
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Onchocerca volvulus 0.0029 0.0125 0.0353
Toxoplasma gondii microneme protein, putative 0.0038 0.0178 0.049
Plasmodium falciparum acyl-CoA synthetase 0.0036 0.0164 1
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0015 0.0016
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.001 0.0006 0.0013
Loa Loa (eye worm) hypothetical protein 0.0029 0.0125 0.0259
Trichomonas vaginalis glucosylceramidase, putative 0.0803 0.4779 1
Trichomonas vaginalis glucosylceramidase, putative 0.0527 0.3118 0.6507
Echinococcus granulosus protein jagged 2 0.0033 0.0149 0.0168
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0015 0.0031
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0071 0.4127
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Brugia malayi Kringle domain containing protein 0.0035 0.0162 0.0339
Loa Loa (eye worm) hypothetical protein 0.0014 0.0033 0.0068
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0048 0.0237 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0015 0.0031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0015 0.001
Trichomonas vaginalis glucosylceramidase, putative 0.0555 0.3288 0.6866
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0036 0.0164 0.5
Loa Loa (eye worm) hypothetical protein 0.0038 0.0178 0.0372
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Schistosoma mansoni cercarial elastase (S01 family) 0.0029 0.0125 0.0134
Plasmodium falciparum importin beta, putative 0.0028 0.0117 0.7038
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0014 0.0033 0.0546
Loa Loa (eye worm) PAN domain-containing protein 0.0038 0.0178 0.0372
Loa Loa (eye worm) hypothetical protein 0.0029 0.0125 0.0259
Loa Loa (eye worm) hypothetical protein 0.0036 0.0164 0.0342
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0073 0.0152
Echinococcus multilocularis notch 0.0033 0.0149 0.0148
Schistosoma mansoni hypothetical protein 0.0032 0.014 0.0152
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0014 0.0033 0.0616
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.014 0.014
Schistosoma mansoni hypothetical protein 0.0032 0.014 0.0152
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Loa Loa (eye worm) hypothetical protein 0.0029 0.0125 0.0259
Leishmania major GTP-binding protein, putative 0.0021 0.0073 0.2317
Brugia malayi PAN domain containing protein 0.0038 0.0178 0.0373
Schistosoma mansoni hypothetical protein 0.0033 0.0149 0.0162
Schistosoma mansoni hypothetical protein 0.0033 0.0149 0.0162
Echinococcus granulosus microtubule associated protein 2 0.1474 0.8819 1
Brugia malayi Calcium binding EGF domain containing protein 0.0027 0.011 0.0231
Echinococcus granulosus ATP dependent DNA helicase Q1 0.001 0.0006 0.0006
Schistosoma mansoni coup transcription factor 0.0011 0.0015 0.001
Schistosoma mansoni hypothetical protein 0.0069 0.0363 0.0405
Onchocerca volvulus 0.0038 0.0178 0.0527
Plasmodium vivax acyl-CoA synthetase, putative 0.0036 0.0164 1
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0185 0.0388
Brugia malayi Delta serrate ligand family protein 0.0033 0.0149 0.0312
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.001 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0048 0.0237 1
Onchocerca volvulus Slit protein homolog 0.0033 0.0149 0.0432
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0152 0.6071
Loa Loa (eye worm) hypothetical protein 0.0015 0.0037 0.0076
Plasmodium falciparum cysteine repeat modular protein 1 0.0035 0.0162 0.9859
Loa Loa (eye worm) hypothetical protein 0.0066 0.0348 0.0727
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0015 0.0031
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0029 0.0125 0.0134
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0033 0.007
Onchocerca volvulus 0.0038 0.0178 0.0527
Brugia malayi EGF-like domain containing protein 0.0033 0.0149 0.0312
Brugia malayi AMP-binding enzyme family protein 0.0014 0.0033 0.007
Loa Loa (eye worm) hypothetical protein 0.0033 0.0149 0.0311
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0185 0.0341
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0073 0.4658
Echinococcus multilocularis Tolloid protein 1 0.0027 0.011 0.011

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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