Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0021 | 0.016 | 0.3816 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0025 | 0.021 | 0.5238 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0021 | 0.016 | 0.0152 |
Trypanosoma cruzi | glutathione-S-transferase/glutaredoxin, putative | 0.0554 | 0.6244 | 1 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0025 | 0.021 | 0.5 |
Echinococcus multilocularis | 0.0015 | 0.0095 | 0.0087 | |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0015 | 0.0095 | 0.2309 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0204 | 0.0275 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0164 | 0.0753 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.0015 | 0.0095 | 0.1995 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0378 | 0.1783 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0257 | 0.2859 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.004 | 0.0378 | 0.0588 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0596 | 0.0814 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.0015 | 0.0095 | 0.1995 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0204 | 0.0275 |
Leishmania major | cytochrome p450-like protein | 0.0025 | 0.0204 | 0.0177 |
Toxoplasma gondii | exonuclease III APE | 0.0021 | 0.016 | 0.0105 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.1813 | 0.2788 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.0164 | 0.0753 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0378 | 0.0461 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0025 | 0.021 | 0.5238 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0128 | 0.1385 | 0.4832 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0296 | 0.1013 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.0015 | 0.0095 | 0.1995 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0164 | 0.0549 |
Loa Loa (eye worm) | hypothetical protein | 0.0554 | 0.6244 | 0.9708 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0015 | 0.0095 | 0.2309 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0095 | 0.042 |
Onchocerca volvulus | 0.0031 | 0.0276 | 0.0184 | |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0164 | 0.0213 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0296 | 0.139 |
Trypanosoma cruzi | glutathione-S-transferase/glutaredoxin, putative | 0.0554 | 0.6244 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0374 | 0.4192 | 0.6518 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.0015 | 0.0095 | 0.1995 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0025 | 0.021 | 1 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.2085 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0518 | 0.1791 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0378 | 0.0588 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0296 | 0.0289 |
Leishmania major | glutathione-S-transferase/glutaredoxin, putative | 0.0554 | 0.6244 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0015 | 0.0095 | 0.2309 |
Brugia malayi | Cytochrome P450 family protein | 0.0015 | 0.0095 | 0.0105 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0378 | 0.0461 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0015 | 0.0095 | 0.2309 |
Loa Loa (eye worm) | cytochrome P450 | 0.0015 | 0.0095 | 0.0105 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.0015 | 0.0095 | 0.1995 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0025 | 0.021 | 1 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0021 | 0.016 | 0.0532 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0518 | 0.2458 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0015 | 0.0095 | 0.2309 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0015 | 0.0095 | 0.2309 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.0015 | 0.0095 | 0.1995 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0021 | 0.016 | 0.0205 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.004 | 0.0378 | 0.0461 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0166 | 0.1813 | 0.2788 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0015 | 0.0095 | 0.2309 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0021 | 0.016 | 0.5 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0036 | 0.033 | 1 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.004 | 0.0378 | 0.0371 |
Trypanosoma brucei | cytochrome P450, putative | 0.0025 | 0.0204 | 0.0177 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0021 | 0.016 | 0.0205 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0015 | 0.0095 | 0.2309 |
Echinococcus granulosus | ferritin | 0.0009 | 0.0025 | 0.0059 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.016 | 0.0105 |
Echinococcus multilocularis | RUN | 0.0021 | 0.0164 | 0.0157 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0518 | 0.2458 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0052 | 0.0518 | 0.0766 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0015 | 0.0095 | 0.2309 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.0164 | 0.0753 |
Brugia malayi | Cytochrome P450 family protein | 0.0057 | 0.0569 | 0.0845 |
Brugia malayi | hypothetical protein | 0.0257 | 0.2859 | 0.4421 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.0015 | 0.0095 | 0.1995 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.0015 | 0.0095 | 0.1995 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0015 | 0.0095 | 0.2309 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.021 | 0.23 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.009 | 0.0953 | 0.3314 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0025 | 0.0204 | 0.5074 |
Brugia malayi | hypothetical protein | 0.0554 | 0.6244 | 0.9708 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.0164 | 0.0157 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.0676 | 0.3219 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0015 | 0.0095 | 0.2309 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0025 | 0.008 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.016 | 0.073 |
Echinococcus multilocularis | expressed protein | 0.0009 | 0.0025 | 0.0017 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.0015 | 0.0095 | 0.1995 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0276 | 0.0387 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.057 | 0.6431 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0394 | 0.4422 | 0.6876 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0276 | 0.1292 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.0015 | 0.0095 | 0.1995 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.0015 | 0.0095 | 0.1995 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0052 | 0.0518 | 0.0766 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0057 | 0.0569 | 0.0846 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0015 | 0.0095 | 0.0306 |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.009 | 0.0953 | 0.1444 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0164 | 0.0213 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0204 | 0.0177 |
Echinococcus multilocularis | geminin | 0.019 | 0.2085 | 0.2079 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0164 | 0.0213 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0025 | 0.008 |
Brugia malayi | Inositol-1 | 0.004 | 0.0378 | 0.0547 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0025 | 0.008 |
Brugia malayi | hypothetical protein | 0.0021 | 0.0164 | 0.0213 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0128 | 0.1385 | 0.1379 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0052 | 0.0519 | 0.0766 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0015 | 0.0095 | 0.2309 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.0021 | 0.0164 | 0.0938 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0036 | 0.033 | 1 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0164 | 0.0753 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0025 | 0.0204 | 0.0177 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0378 | 0.0461 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0015 | 0.0095 | 0.2309 |
Schistosoma mansoni | lipoxygenase | 0.009 | 0.0944 | 0.4507 |
Trichomonas vaginalis | ferritin, putative | 0.0009 | 0.0025 | 0.0038 |
Brugia malayi | Doublecortin family protein | 0.0021 | 0.0164 | 0.0213 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0374 | 0.4192 | 0.6624 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0374 | 0.4192 | 0.6518 |
Onchocerca volvulus | 0.009 | 0.0953 | 0.1297 | |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0518 | 0.0766 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0052 | 0.0518 | 0.0766 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0374 | 0.4192 | 0.6518 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.001 | 0.003 | 0.0022 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0113 | 0.1214 | 0.1852 |
Echinococcus granulosus | RUN | 0.0021 | 0.0164 | 0.0549 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0374 | 0.4192 | 0.6518 |
Schistosoma mansoni | lipoxygenase | 0.0128 | 0.1385 | 0.6631 |
Schistosoma mansoni | apoferritin-2 | 0.0009 | 0.0025 | 0.008 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0518 | 0.1791 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.016 | 0.0248 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.057 | 0.6431 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0519 | 0.246 |
Mycobacterium leprae | Conserved hypothetical protein | 0.0015 | 0.0095 | 0.2309 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0021 | 0.016 | 0.3816 |
Schistosoma mansoni | ap endonuclease | 0.0021 | 0.016 | 0.073 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.057 | 0.6431 | 1 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0021 | 0.016 | 0.0248 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0021 | 0.016 | 0.0105 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0052 | 0.0518 | 0.0511 |
Echinococcus multilocularis | GPCR, family 2 | 0.0052 | 0.0518 | 0.0511 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0518 | 0.2458 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.0015 | 0.0095 | 0.1995 |
Echinococcus granulosus | GPCR family 2 | 0.0052 | 0.0518 | 0.1791 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0025 | 0.0204 | 0.0275 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0015 | 0.0095 | 0.2309 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0025 | 0.008 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.0164 | 0.0213 |
Brugia malayi | Cytochrome P450 family protein | 0.0025 | 0.0204 | 0.0275 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0021 | 0.016 | 0.0105 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0025 | 0.008 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0052 | 0.0518 | 0.0511 |
Schistosoma mansoni | inositol monophosphatase | 0.004 | 0.0378 | 0.1783 |
Echinococcus granulosus | geminin | 0.019 | 0.2085 | 0.7286 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0025 | 0.0204 | 0.0275 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0025 | 0.021 | 0.5238 |
Loa Loa (eye worm) | inositol-1 | 0.004 | 0.0378 | 0.0547 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0015 | 0.0095 | 0.2309 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0025 | 0.021 | 0.0187 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0257 | 0.2859 | 0.2853 |
Echinococcus multilocularis | ferritin | 0.0009 | 0.0025 | 0.0017 |
Mycobacterium leprae | conserved hypothetical protein | 0.0025 | 0.021 | 0.6063 |
Schistosoma mansoni | ferritin light chain | 0.0009 | 0.0025 | 0.008 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.004 | 0.0378 | 1 |
Mycobacterium leprae | putative cytochrome p450 | 0.0015 | 0.0095 | 0.2309 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0015 | 0.0095 | 0.2309 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0276 | 0.0388 |
Loa Loa (eye worm) | hypothetical protein | 0.0113 | 0.1214 | 0.1852 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0025 | 0.021 | 0.0187 |
Onchocerca volvulus | 0.0052 | 0.0519 | 0.0583 | |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.0015 | 0.0095 | 0.1995 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.004 | 0.0378 | 0.0461 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0166 | 0.1813 | 0.2788 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.009 | 0.0953 | 0.4549 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.057 | 0.6431 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0113 | 0.1214 | 0.5806 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.057 | 0.6431 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0166 | 0.1813 | 0.2788 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0374 | 0.4192 | 0.6518 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.004 | 0.0378 | 0.0588 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.0015 | 0.0095 | 0.1995 |
Schistosoma mansoni | hypothetical protein | 0.019 | 0.2085 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.004 | 0.0378 | 0.1299 |
Schistosoma mansoni | hypothetical protein | 0.0052 | 0.0518 | 0.2458 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.0164 | 0.0753 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0025 | 0.021 | 0.0187 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.0164 | 0.0549 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.0015 | 0.0095 | 0.1995 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.0015 | 0.0095 | 0.1995 |
Schistosoma mansoni | survival motor neuron protein | 0.0052 | 0.0519 | 0.246 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.057 | 0.6431 | 1 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.0015 | 0.0095 | 0.1995 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.057 | 0.6431 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.057 | 0.6431 | 1 |
Onchocerca volvulus | 0.0554 | 0.6244 | 1 | |
Echinococcus granulosus | expressed protein | 0.0009 | 0.0025 | 0.0059 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0015 | 0.0095 | 0.2309 |
Toxoplasma gondii | prostaglandin-E synthase | 0.0554 | 0.6244 | 1 |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0025 | 0.021 | 1 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0025 | 0.021 | 0.6063 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0021 | 0.016 | 0.4417 |
Brugia malayi | cytochrome P450 | 0.0015 | 0.0095 | 0.0105 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0015 | 0.0095 | 0.2309 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0296 | 0.139 |
Schistosoma mansoni | cytochrome P450 | 0.0015 | 0.0095 | 0.042 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0374 | 0.4192 | 0.6518 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0953 | 0.1444 |
Loa Loa (eye worm) | histone methyltransferase | 0.001 | 0.003 | 0.0002 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.0164 | 0.0549 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0021 | 0.016 | 0.0105 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0015 | 0.0095 | 0.2309 |
Schistosoma mansoni | ferritin | 0.0009 | 0.0025 | 0.008 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0025 | 0.021 | 0.0187 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.0015 | 0.0095 | 0.1995 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0164 | 0.0157 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0015 | 0.0095 | 0.2309 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.001 | 0.003 | 0.0076 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.004 | 0.0378 | 1 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.009 | 0.0953 | 0.0946 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.0164 | 0.0157 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0021 | 0.016 | 0.7285 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.004 | 0.0378 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0374 | 0.4192 | 0.6518 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.0015 | 0.0095 | 0.1995 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0394 | 0.4422 | 0.6876 |
Loa Loa (eye worm) | hypothetical protein | 0.0257 | 0.2859 | 0.4421 |
Trypanosoma brucei | Prostaglandin E synthase | 0.0554 | 0.6244 | 1 |
Plasmodium falciparum | LCCL domain-containing protein | 0.0021 | 0.0164 | 0.0938 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.0015 | 0.0095 | 0.1995 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
log(1/MIC) (functional) | = -2.569 | Antibacterial activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition by two-fold serial dilution method | ChEMBL. | 817022 |
MIC (functional) | = 67.57 ug ml-1 | Antitubercular activity against Mycobacterium tuberculosis | ChEMBL. | 24246731 |
MIC (functional) | = 371 uM | Antitubercular activity against Mycobacterium tuberculosis H37Rv ATCC 27294 by BACTEC 960 assay | ChEMBL. | 24836065 |
MIC (functional) | = 371 umol/L | Antibacterial activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition by two-fold serial dilution method | ChEMBL. | 817022 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.