TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 203.28 | Formula: C13H17NO
H donors: 1 H acceptors: 1 LogP: 2.25 Rotable bonds: 0
Rule of 5 violations (Lipinski): 1
SMILES: CN1CC[C@H]2C[C@H]1Cc1c2cc(cc1)O
InChi: 1S/C13H17NO/c1-14-5-4-10-7-11(14)6-9-2-3-12(15)8-13(9)10/h2-3,8,10-11,15H,4-7H2,1H3/t10-,11+/m0/s1
InChiKey: JANBJBABWKFLQT-WDEREUQCSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	hypothetical protein	0.1832	1	1
Echinococcus granulosus	Ataxin 2 N terminaldomain containing protein	0.01	0.0419	0.0416
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0033	0.0049	0.0046
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase	0.0033	0.0049	0.0046
Giardia lamblia	Nitric oxide synthase, inducible	0.0044	0.0112	1
Brugia malayi	mothers against decapentaplegic homolog 3	0.0031	0.004	0.0037
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0046
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Plasmodium falciparum	ubiquitin specific protease, putative	0.0033	0.0049	0.0421
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase family 2 protein	0.0033	0.0049	0.0421
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.1614	0.8796	0.8795
Trichomonas vaginalis	GTP-binding protein (z) alpha subunit, gnaz, putative	0.0069	0.0252	1
Schistosoma mansoni	Smad4	0.0031	0.004	0.0037
Schistosoma mansoni	ubiquitin-specific peptidase 22 (C19 family)	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	hypothetical protein	0.0173	0.0827	0.0824
Loa Loa (eye worm)	G protein alpha subunit 3	0.0069	0.0252	0.0249
Plasmodium falciparum	ataxin-2 like protein, putative	0.0222	0.1096	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0252	0.0249
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Schistosoma mansoni	NADPH flavin oxidoreductase	0.0025	0.0007	0.0004
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0046
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0033	0.0049	0.0421
Brugia malayi	hypothetical protein	0.0069	0.0252	0.0249
Schistosoma mansoni	ubiquitin-specific peptidase 44 (C19 family)	0.0033	0.0049	0.0046
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 16	0.0033	0.0049	0.0046
Schistosoma mansoni	calpain-7 (C02 family)	0.0033	0.0049	0.0046
Echinococcus multilocularis	guanine nucleotide binding protein (G protein)	0.0069	0.0252	0.0249
Toxoplasma gondii	HEAT repeat-containing protein	0.0033	0.0051	0.0442
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	hypothetical protein	0.0141	0.0645	0.0643
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0568	0.3009	0.3007
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0295	0.2678
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.1614	0.8796	0.8795
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 5	0.0033	0.0049	0.0046
Schistosoma mansoni	hypothetical protein	0.0115	0.0505	0.0502
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 22	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	smad1 5 8 and	0.007	0.0253	0.025
Brugia malayi	GTP-binding regulatory protein alpha chain - starfish, putative	0.0069	0.0252	0.0249
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.0077	0.0295	0.0293
Echinococcus granulosus	expressed protein	0.0069	0.0252	0.0249
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0295	1
Echinococcus granulosus	survival motor neuron protein 1	0.0278	0.1408	0.1406
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0053	0.0163	0.016
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0033	0.0049	0.0421
Onchocerca volvulus		0.0069	0.0252	0.0996
Brugia malayi	MH2 domain containing protein	0.0031	0.004	0.0037
Giardia lamblia	Hypothetical protein	0.0044	0.0112	1
Trichomonas vaginalis	NADPH fad oxidoreductase, putative	0.0044	0.0112	0.4391
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0057	0.0182	0.0179
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	GTP-binding protein (I) alpha-1subunit gnai1	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	PAS domain containing protein	0.0057	0.0185	0.0182
Brugia malayi	G-protein alpha subunit	0.0069	0.0252	0.0249
Brugia malayi	RNA, U transporter 1	0.0094	0.0388	0.0386
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.1849
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Brugia malayi	MH1 domain containing protein	0.007	0.0253	0.025
Schistosoma mansoni	ubiquitin-specific peptidase 8 (C19 family)	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	gtp binding protein (I) alpha 1subunit	0.0069	0.0252	0.0249
Echinococcus granulosus	smad	0.007	0.0253	0.025
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	transcription factor SMAD2	0.1021	0.5514	0.5513
Schistosoma mansoni	calpain-7 (C02 family)	0.0033	0.0049	0.0046
Schistosoma mansoni	cytochrome P450 reductase	0.005	0.0143	0.0141
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	ubiquitin-specific peptidase 10 (C19 family)	0.0033	0.0049	0.0046
Echinococcus multilocularis	methionine synthase reductase	0.0031	0.0038	0.0035
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Schistosoma mansoni	ubiquitin-specific peptidase 46 (C19 family)	0.0033	0.0049	0.0046
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus granulosus	guanine nucleotide binding protein G protein	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Loa Loa (eye worm)	RNA binding protein	0.0568	0.3009	0.3007
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0645	0.0643
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus granulosus	ubiquitin specific peptidase c family	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Plasmodium falciparum	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0033	0.0049	0.0421
Trypanosoma cruzi	PAB1-binding protein , putative	0.0222	0.1096	1
Schistosoma mansoni	tar DNA-binding protein	0.0568	0.3009	0.3007
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus granulosus	guanine nucleotide binding protein subunit	0.0069	0.0252	0.0249
Echinococcus multilocularis	u4:u6.u5 tri snrnp associated protein 2	0.0033	0.0049	0.0046
Trypanosoma cruzi	p450 reductase, putative	0.005	0.0143	0.1286
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0295	1
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 36	0.0033	0.0049	0.0046
Loa Loa (eye worm)	guanine nucleotide-binding protein alpha-6 subunit	0.0069	0.0252	0.0249
Brugia malayi	FAD binding domain containing protein	0.005	0.0143	0.0141
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0053	0.0163	0.016
Echinococcus granulosus	Ubiquitin carboxyl terminal hydrolase 48	0.0033	0.0049	0.0046
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 12	0.0033	0.0049	0.0046
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 5	0.0033	0.0049	0.0046
Loa Loa (eye worm)	indoleamine 2,3-dioxygenase	0.1832	1	1
Mycobacterium ulcerans	formate dehydrogenase H FdhF	0.005	0.0143	0.2112
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.1731	0.9445	0.9444
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	guanine nucleotide binding protein (G protein)	0.0069	0.0252	0.0249
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Leishmania major	ubiqitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 47	0.0033	0.0049	0.0046
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0033	0.0049	0.1849
Echinococcus granulosus	Smad4	0.007	0.0253	0.025
Loa Loa (eye worm)	hypothetical protein	0.0192	0.0931	0.0928
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Trypanosoma cruzi	importin beta-1 subunit, putative	0.0027	0.0016	0.0125
Plasmodium vivax	U4/U6.U5 tri-snRNP-associated protein 2, putative	0.0033	0.0049	0.0421
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Brugia malayi	N-terminal motif family protein	0.0415	0.2164	0.2162
Loa Loa (eye worm)	MH1 domain-containing protein	0.0031	0.004	0.0037
Schistosoma mansoni	tar DNA-binding protein	0.0568	0.3009	0.3007
Brugia malayi	Guanine nucleotide-binding protein alpha-12 subunit, putative	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Leishmania major	GTP-binding protein, putative	0.0024	0.0003	0.0025
Loa Loa (eye worm)	MH1 domain-containing protein	0.007	0.0253	0.025
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	tar DNA-binding protein	0.0568	0.3009	0.3007
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0168	0.08	0.0797
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Schistosoma mansoni	TGF-beta signal transducer Smad2	0.007	0.0253	0.025
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Toxoplasma gondii	UBA/TS-N domain-containing protein	0.0033	0.0049	0.0421
Brugia malayi	hypothetical protein	0.0192	0.0931	0.0928
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 47	0.0033	0.0049	0.0046
Schistosoma mansoni	ubiquitin-specific peptidase 4 (C19 family)	0.0033	0.0049	0.0046
Echinococcus multilocularis	Ubiquitin carboxyl terminal hydrolase 48	0.0033	0.0049	0.0046
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0033	0.0049	0.421
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2)	0.0051	0.0148	0.5
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Schistosoma mansoni	ubiquitin-specific peptidase 9X (C19 family)	0.0033	0.0049	0.0046
Schistosoma mansoni	ubiquitin-specific peptidase 30 (C19 family)	0.0033	0.0049	0.0046
Trichomonas vaginalis	sulfite reductase, putative	0.005	0.0143	0.5648
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	hypothetical protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0027	0.0015	0.0115
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0027	0.0016	0.0551
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Leishmania major	p450 reductase, putative	0.005	0.0143	0.1308
Echinococcus multilocularis	survival motor neuron protein 1	0.0278	0.1408	0.1406
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0415	0.2164	0.2162
Schistosoma mansoni	Smad4	0.007	0.0253	0.025
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.0077	0.0295	0.2678
Schistosoma mansoni	peptidase Clp (S14 family)	0.0077	0.0295	0.0293
Onchocerca volvulus		0.0069	0.0252	0.0996
Schistosoma mansoni	ubiquitin-specific peptidase 42 (C19 family)	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Brugia malayi	hypothetical protein	0.0173	0.0827	0.0824
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Onchocerca volvulus		0.0033	0.0049	0.0041
Trypanosoma brucei	cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0421
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Onchocerca volvulus	Huntingtin homolog	0.0141	0.0645	0.285
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase 5, putative	0.0033	0.0049	0.1849
Echinococcus multilocularis	indoleamine 2,3 dioxygenase 2	0.1832	1	1
Schistosoma mansoni	Smad4	0.0031	0.004	0.0037
Plasmodium falciparum	ubiquitin specific protease, putative	0.0033	0.0049	0.0421
Trypanosoma cruzi	PAB1-binding protein , putative	0.0222	0.1096	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Trypanosoma cruzi	cytochrome P450 reductase, putative	0.005	0.0143	0.1286
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.1614	0.8796	0.8795
Echinococcus multilocularis	NADPH cytochrome P450 reductase	0.005	0.0143	0.0141
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 24	0.0033	0.0049	0.0046
Schistosoma mansoni	cellular tumor antigen P53	0.0058	0.019	0.0187
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0027	0.0015	0.0115
Echinococcus granulosus	methionine synthase reductase	0.0031	0.0038	0.0035
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.1614	0.8796	0.8795
Schistosoma mansoni	family C19 unassigned peptidase (C19 family)	0.0033	0.0049	0.0046
Schistosoma mansoni	importin beta-1	0.0033	0.0051	0.0048
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	pax transcription factor protein 2	0.0263	0.1321	0.1318
Brugia malayi	MH2 domain containing protein	0.1021	0.5514	0.5513
Loa Loa (eye worm)	MH2 domain-containing protein	0.007	0.0253	0.025
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 14	0.0033	0.0049	0.421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Onchocerca volvulus		0.0033	0.0049	0.0041
Echinococcus multilocularis	ubiquitin specific protease 41	0.0033	0.0049	0.0046
Schistosoma mansoni	GTP-binding protein (q) alpha-11 subunit gna11	0.0069	0.0252	0.0249
Schistosoma mansoni	smad	0.007	0.0253	0.025
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Onchocerca volvulus		0.0058	0.019	0.0707
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Brugia malayi	MH2 domain containing protein	0.007	0.0253	0.025
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Loa Loa (eye worm)	hypothetical protein	0.0038	0.0081	0.0078
Loa Loa (eye worm)	GTP-binding regulatory protein alpha chain	0.0069	0.0252	0.0249
Leishmania major	NADPH-cytochrome p450 reductase-like protein	0.005	0.0143	0.1308
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Onchocerca volvulus		0.0173	0.0827	0.3704
Schistosoma mansoni	trimeric G-protein alpha o subunit	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	hypothetical protein	0.0141	0.0645	0.0643
Brugia malayi	hypothetical protein	0.0278	0.1408	0.1406
Brugia malayi	guanine nucleotide-binding protein G(o), alpha subunit, putative	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	Ataxin 2, N terminal,domain containing protein	0.01	0.0419	0.0416
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0295	0.5
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.1614	0.8796	0.8795
Loa Loa (eye worm)	MH2 domain-containing protein	0.1021	0.5514	0.5513
Loa Loa (eye worm)	hypothetical protein	0.0077	0.0295	0.0293
Loa Loa (eye worm)	hypothetical protein	0.0031	0.004	0.0037
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Entamoeba histolytica	G protein alpha subunit, putative	0.0069	0.0252	1
Echinococcus granulosus	snurportin 1	0.0353	0.1821	0.1819
Schistosoma mansoni	smad1 5 8 and	0.007	0.0253	0.025
Plasmodium vivax	hypothetical protein, conserved	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	survival motor neuron protein	0.0057	0.0182	0.0179
Loa Loa (eye worm)	nucleolar RNA-associated protein alpha	0.0353	0.1821	0.1819
Trypanosoma brucei	NADPH-cytochrome p450 reductase, putative	0.005	0.0143	0.1286
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	transfer RNA-Lys	0.0042	0.0103	0.01
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	GTP-binding protein (I) alpha-1subunit gnai1	0.0069	0.0252	0.0249
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	Pax transcription factor protein 2	0.0263	0.1321	0.1318
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0046
Toxoplasma gondii	hypothetical protein	0.0027	0.0015	0.0115
Schistosoma mansoni	aryl hydrocarbon receptor	0.0057	0.0185	0.0182
Brugia malayi	ubiquitin carboxyl-terminal hydrolase 46	0.0033	0.0049	0.0046
Brugia malayi	latrophilin 2 splice variant baaae	0.0115	0.0505	0.0502
Echinococcus granulosus	indoleamine 23 dioxygenase 2	0.1832	1	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma brucei	NADPH--cytochrome P450 reductase, putative	0.005	0.0143	0.1286
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0252	0.0249
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 12	0.0033	0.0049	0.0046
Brugia malayi	RNA recognition motif domain containing protein	0.0568	0.3009	0.3007
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Loa Loa (eye worm)	Smad1	0.007	0.0253	0.025
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0053	0.0163	0.016
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase family 2, putative	0.0033	0.0049	0.0421
Brugia malayi	bHLH-PAS transcription factor	0.0042	0.0103	0.01
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma cruzi	cytochrome P450 reductase, putative	0.005	0.0143	0.1286
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.0069	0.0252	0.0249
Schistosoma mansoni	ubiquitin carboxyl-terminal hydrolase of the cysteine proteinase fold	0.0033	0.0049	0.0046
Toxoplasma gondii	hypothetical protein	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	TAR-binding protein	0.0568	0.3009	0.3007
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Giardia lamblia	DUB-1	0.0033	0.0049	0.421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Brugia malayi	flavodoxin family protein	0.005	0.0143	0.0141
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.1614	0.8796	0.8795
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	guanine nucleotide-binding protein alpha-3 subunit, putative	0.0069	0.0252	0.0249
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	MH1 domain containing protein	0.007	0.0253	0.025
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	GPCR, family 2	0.0053	0.0163	0.016
Echinococcus granulosus	guanine nucleotide binding protein subunit	0.0069	0.0252	0.0249
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0252	0.0249
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase 46	0.0033	0.0049	0.0046
Echinococcus multilocularis	tar DNA binding protein	0.0568	0.3009	0.3007
Echinococcus granulosus	mothers against decapentaplegic 6	0.0031	0.004	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0033	0.0049	0.1849
Brugia malayi	MH1 domain containing protein	0.0038	0.0081	0.0078
Plasmodium vivax	NADPH-cytochrome p450 reductase, putative	0.005	0.0143	0.1286
Trypanosoma brucei	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	Smad4	0.007	0.0253	0.025
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Toxoplasma gondii	flavodoxin domain-containing protein	0.0025	0.0005	0.0017
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 4	0.0033	0.0049	0.421
Echinococcus multilocularis	ubiquitin specific peptidase (c family) ubiquitin terminal hydrolase	0.0033	0.0049	0.0046
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Schistosoma mansoni	tar DNA-binding protein	0.0568	0.3009	0.3007
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	Guanine nucleotide-binding protein alpha-3 subunit, putative	0.0069	0.0252	0.0249
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0421
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0033	0.0049	0.0046
Schistosoma mansoni	GTP-binding protein alpha subunit	0.0069	0.0252	0.0249
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0046
Onchocerca volvulus		0.0069	0.0252	0.0996
Trichomonas vaginalis	importin beta-1, putative	0.0027	0.0016	0.0551
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0053	0.0163	0.016
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0295	1
Echinococcus granulosus	TGF beta signal transducer SmadC	0.007	0.0253	0.025
Echinococcus granulosus	NADPH cytochrome P450 reductase	0.005	0.0143	0.0141
Echinococcus multilocularis	mothers against decapentaplegic 5	0.007	0.0253	0.025
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	snurportin 1	0.0353	0.1821	0.1819
Schistosoma mansoni	GTP-binding protein alpha subunit gna	0.0069	0.0252	0.0249
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0051	0.0048
Schistosoma mansoni	GTP-binding protein (q) alpha-11 subunit gna11	0.0069	0.0252	0.0249
Echinococcus granulosus	tumor protein p63	0.0398	0.2068	0.2066
Brugia malayi	hypothetical protein	0.0222	0.1096	0.1093
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 4	0.0033	0.0049	0.0046
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0033	0.0049	0.1849
Brugia malayi	FAD binding domain containing protein	0.0031	0.0038	0.0035
Toxoplasma gondii	flavodoxin domain-containing protein	0.0025	0.0005	0.0017
Loa Loa (eye worm)	hypothetical protein	0.0115	0.0505	0.0502
Toxoplasma gondii	LsmAD domain-containing protein	0.0222	0.1096	1
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Echinococcus granulosus	u4:u6.u5 tri snrnp associated protein 2	0.0033	0.0049	0.0046
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Plasmodium vivax	flavodoxin domain containing protein	0.0044	0.0112	0.1
Echinococcus granulosus	importin subunit beta 1	0.0033	0.0051	0.0048
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.0077	0.0295	0.0293
Trypanosoma cruzi	Peptidase C19, ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Brugia malayi	hypothetical protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Echinococcus granulosus	ubiquitin specific protease 41	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0163	0.016
Echinococcus granulosus	guanine nucleotide binding protein G protein	0.0069	0.0252	0.0249
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	nuclear factor I	0.0038	0.0081	0.0078
Brugia malayi	Latrophilin receptor protein 2	0.0053	0.0163	0.016
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	GTP-binding protein (I) alpha subunit gnai	0.0069	0.0252	0.0249
Plasmodium vivax	ubiquitin specific protease, putative	0.0033	0.0049	0.0421
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	hypothetical protein	0.01	0.0419	0.0416
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0252	0.0249
Loa Loa (eye worm)	hypothetical protein	0.0168	0.08	0.0797
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Brugia malayi	RNA binding protein	0.0568	0.3009	0.3007
Trypanosoma brucei	importin beta-1 subunit, putative	0.0033	0.0051	0.0442
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	ubiquitin specific peptidase 39	0.0033	0.0049	0.0046
Schistosoma mansoni	ubiquitin-specific peptidase 16 (C19 family)	0.0033	0.0049	0.0046
Schistosoma mansoni	5-methyl tetrahydrofolate-homocysteine methyltransferase reductase	0.0031	0.0038	0.0035
Trypanosoma brucei	PAB1-binding protein , putative	0.0222	0.1096	1
Schistosoma mansoni	GTP-binding protein alpha subunit gna	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	peptidase	0.0033	0.0049	0.0046
Trichomonas vaginalis	GTP-binding protein alpha subunit, gna, putative	0.0069	0.0252	1
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Schistosoma mansoni	ubiquitin-specific peptidase 5 (C19 family)	0.0033	0.0049	0.0046
Onchocerca volvulus		0.0263	0.1321	0.6029
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 14	0.0033	0.0049	0.0046
Loa Loa (eye worm)	heterotrimeric G protein alpha subunit	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	mothers against decapentaplegic 2	0.0031	0.004	0.0037
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0168	0.08	0.0797
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0033	0.0049	0.0046
Trypanosoma brucei	NADPH--cytochrome P450 reductase, putative	0.005	0.0143	0.1286
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Echinococcus multilocularis	expressed protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	hypothetical protein	0.005	0.0143	0.0141
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	importin subunit beta 1	0.0033	0.0051	0.0048
Trichomonas vaginalis	GTP-binding protein (O) alpha subunit, gnao, putative	0.0069	0.0252	1
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 7	0.0033	0.0049	0.0046
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.1614	0.8796	0.8795
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase 5, putative	0.0033	0.0049	0.1849
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 16	0.0033	0.0049	0.0046
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0033	0.0049	0.1849
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	ubiquitin-specific peptidase 14 (C19 family)	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Trichomonas vaginalis	GTP-binding protein alpha subunit, gna, putative	0.0069	0.0252	1
Echinococcus granulosus	peptidase Clp S14 family	0.0051	0.0148	0.0146
Brugia malayi	Importin beta-1 subunit	0.0033	0.0051	0.0048
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)	0.0051	0.0148	0.4744
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Brugia malayi	MH2 domain containing protein	0.007	0.0253	0.025
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	family C19 non-peptidase homologue (C19 family)	0.0033	0.0049	0.0046
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Schistosoma mansoni	tar DNA-binding protein	0.0568	0.3009	0.3007
Leishmania major	importin beta-1 subunit, putative	0.0027	0.0016	0.015
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma cruzi	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 8	0.0033	0.0049	0.0046
Schistosoma mansoni	hypothetical protein	0.0353	0.1821	0.1819
Trichomonas vaginalis	Harbinger-1_Harbinger/PIFA2 transposable element protein	0.0033	0.0049	0.1849
Echinococcus multilocularis	Peptidase C19, ubiquitin carboxyl terminal hydrolase 2	0.0033	0.0049	0.0046
Loa Loa (eye worm)	MH2 domain-containing protein	0.0031	0.004	0.0037
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 20	0.0033	0.0049	0.0046
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Loa Loa (eye worm)	hypothetical protein	0.0058	0.019	0.0187
Echinococcus multilocularis	guanine nucleotide binding protein subunit	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	NADPH dependent diflavin oxidoreductase 1	0.005	0.0143	0.0141
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 36	0.0033	0.0049	0.0046
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.0077	0.0295	1
Giardia lamblia	Ubiquitin carboxyl-terminal hydrolase 14	0.0033	0.0049	0.421
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Schistosoma mansoni	ubiquitin-specific peptidase 24 (C19 family)	0.0033	0.0049	0.0046
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0077	0.0295	0.2678
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Toxoplasma gondii	ubiquitin-specific protease USP4	0.0033	0.0049	0.0421
Trypanosoma cruzi	cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0421
Echinococcus multilocularis	peptidase Clp (S14 family)	0.0051	0.0148	0.0146
Schistosoma mansoni	hypothetical protein	0.1832	1	1
Onchocerca volvulus	Rap guanine nucleotide exchange factor 1 homolog	0.0415	0.2164	1
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Brugia malayi	hypoxia-induced factor 1	0.0177	0.0849	0.0846
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	tumor protein p63	0.0398	0.2068	0.2066
Plasmodium falciparum	ataxin-2 like protein, putative	0.0222	0.1096	1
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Echinococcus granulosus	NADPH dependent diflavin oxidoreductase 1	0.005	0.0143	0.0141
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0168	0.08	0.0797
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.1614	0.8796	0.8795
Echinococcus granulosus	gtp binding protein I alpha 1subunit	0.0069	0.0252	0.0249
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 1, putative	0.0033	0.0049	0.0421
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Entamoeba histolytica	hypothetical protein	0.0033	0.0049	0.1849
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	ubiquitin-specific peptidase 45 (C19 family)	0.0033	0.0049	0.0046
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 24	0.0033	0.0049	0.0046
Echinococcus multilocularis	ubiquitin specific peptidase 42 (C19 family)	0.0033	0.0049	0.0046
Echinococcus granulosus	ubiquitin specific peptidase 30 (C19 family)	0.0033	0.0049	0.0046
Brugia malayi	Probable ClpP-like protease	0.0077	0.0295	0.0293
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP)	0.0051	0.0148	0.5
Schistosoma mansoni	hypothetical protein	0.0053	0.0163	0.016
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0053	0.0163	0.016
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Toxoplasma gondii	ubiquitin specific protease 39 isoform 2, putative	0.0033	0.0049	0.0421
Onchocerca volvulus	Huntingtin homolog	0.0141	0.0645	0.285
Brugia malayi	ubiquitin specific protease 14	0.0033	0.0049	0.0046
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Trichomonas vaginalis	ubiquitin specific protease, putative	0.0033	0.0049	0.1849
Brugia malayi	guanine nucleotide-binding protein G-o protein alpha subunit	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma brucei	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	diflavin oxidoreductase	0.0025	0.0005	0.0002
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.1614	0.8796	0.8795
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Plasmodium falciparum	nitric oxide synthase, putative	0.005	0.0143	0.1286
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.0077	0.0295	0.2678
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Trichomonas vaginalis	GTP-binding protein (q) alpha-11 subunit, gna11, putative	0.0069	0.0252	1
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 13, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	smad1 5 8 and	0.007	0.0253	0.025
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Echinococcus granulosus	mothers against decapentaplegic 5	0.007	0.0253	0.025
Leishmania major	hypothetical protein, conserved	0.0222	0.1096	1
Loa Loa (eye worm)	hypothetical protein	0.0222	0.1096	0.1093
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0053	0.0163	0.016
Onchocerca volvulus		0.0033	0.0049	0.0041
Loa Loa (eye worm)	hypoxia-induced factor 1	0.0177	0.0849	0.0846
Loa Loa (eye worm)	guanine nucleotide-binding protein alpha-12 subunit	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Plasmodium vivax	importin-beta 2, putative	0.0033	0.0051	0.0442
Loa Loa (eye worm)	hypothetical protein	0.0069	0.0252	0.0249
Schistosoma mansoni	ubiquitin-specific peptidase 2 (C19 family)	0.0033	0.0049	0.0046
Leishmania major	ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative	0.0033	0.0049	0.0445
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 22	0.0033	0.0049	0.0046
Leishmania major	cytochrome P450 reductase, putative	0.0044	0.0112	0.1022
Echinococcus granulosus	5'partial\|Ubiquitin carboxyl terminal hydrolase 48	0.0033	0.0049	0.0046
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0046
Brugia malayi	Guanine nucleotide-binding protein alpha-3 subunit, putative	0.0069	0.0252	0.0249
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Schistosoma mansoni	single-minded	0.0057	0.0185	0.0182
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 7	0.0033	0.0049	0.0046
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 23	0.0033	0.0049	0.0046
Brugia malayi	Guanine nucleotide-binding protein alpha-6 subunit, putative	0.0069	0.0252	0.0249
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase 14	0.0033	0.0049	0.0421
Echinococcus granulosus	tar DNA binding protein	0.0568	0.3009	0.3007
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0295	1
Trichomonas vaginalis	conserved hypothetical protein	0.0033	0.0049	0.1849
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Giardia lamblia	Hypothetical protein	0.0033	0.0049	0.421
Echinococcus granulosus	single minded 2	0.0042	0.0103	0.01
Trypanosoma cruzi	NADPH-dependent FMN/FAD containing oxidoreductase, putative	0.005	0.0143	0.1286
Brugia malayi	MH1 domain containing protein	0.0038	0.0081	0.0078
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 20	0.0033	0.0049	0.0046
Trichomonas vaginalis	G protein (olf) alpha subunit, gnal, putative	0.0069	0.0252	1
Brugia malayi	hypothetical protein	0.0143	0.0661	0.0658
Loa Loa (eye worm)	FAD binding domain-containing protein	0.0031	0.0038	0.0035
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Loa Loa (eye worm)	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0046
Schistosoma mansoni	smad	0.0031	0.004	0.0037
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Brugia malayi	guanine nucleotide-binding protein alpha-7 subunit, putative	0.0069	0.0252	0.0249
Brugia malayi	Smad1	0.007	0.0253	0.025
Echinococcus granulosus	Peptidase C19 ubiquitin carboxyl terminal hydrolase 2	0.0033	0.0049	0.0046
Schistosoma mansoni	hypothetical protein	0.0053	0.0163	0.016
Schistosoma mansoni	ubiquitin-specific peptidase 7 (C19 family)	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Plasmodium falciparum	importin beta, putative	0.0033	0.0051	0.0442
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 14	0.0033	0.0049	0.0046
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Brugia malayi	TAR-binding protein	0.0568	0.3009	0.3007
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	Importin beta-1 subunit, putative	0.0027	0.0016	0.0551
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Onchocerca volvulus		0.0057	0.0182	0.0669
Schistosoma mansoni	hypothetical protein	0.0057	0.0182	0.0179
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Loa Loa (eye worm)	FAD binding domain-containing protein	0.005	0.0143	0.0141
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Schistosoma mansoni	GTP-binding protein (I) alpha-2 subunit gnai2	0.0069	0.0252	0.0249
Schistosoma mansoni	ubiquitin-specific peptidase 48 (C19 family)	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0049	0.0046
Echinococcus multilocularis	expressed protein	0.0069	0.0252	0.0249
Schistosoma mansoni	hypothetical protein	0.0053	0.0163	0.016
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma brucei	NADPH-dependent diflavin oxidoreductase 1	0.005	0.0143	0.1286
Echinococcus multilocularis	guanine nucleotide binding protein subunit	0.0069	0.0252	0.0249
Plasmodium vivax	ataxin-2 like protein, putative	0.0222	0.1096	1
Echinococcus granulosus	GPCR family 2	0.0053	0.0163	0.016
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	GTP-binding protein alpha subunit, gna, putative	0.0069	0.0252	1
Echinococcus multilocularis	mothers against decapentaplegic 6	0.0031	0.004	0.0037
Onchocerca volvulus		0.0042	0.0103	0.0294
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Schistosoma mansoni	GTP-binding protein alpha subunit	0.0069	0.0252	0.0249
Toxoplasma gondii	ubiquitin carboxyl-terminal hydrolase	0.0033	0.0049	0.0421
Echinococcus multilocularis	TGF beta signal transducer SmadC	0.007	0.0253	0.025
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	smad	0.007	0.0253	0.025
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma cruzi	ubiquitin hydrolase, putative	0.0033	0.0049	0.0421
Schistosoma mansoni	hypothetical protein	0.0053	0.0163	0.016
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trypanosoma brucei	importin beta-1 subunit, putative	0.0033	0.0051	0.0442
Echinococcus granulosus	ubiquitin carboxyl terminal hydrolase 8	0.0033	0.0049	0.0046
Plasmodium falciparum	ubiquitin carboxyl-terminal hydrolase, putative	0.0033	0.0049	0.0421
Entamoeba histolytica	ubiquitin carboxyl-terminal hydrolase domain containing protein	0.0033	0.0049	0.1849
Plasmodium vivax	ubiquitin carboxyl-terminal hydrolase 2, putative	0.0033	0.0049	0.0421
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Trichomonas vaginalis	GTP-binding protein alpha subunit, gna, putative	0.0069	0.0252	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Entamoeba histolytica	hypothetical protein	0.0027	0.0016	0.0551
Brugia malayi	Ubiquitin carboxyl-terminal hydrolase family protein	0.0033	0.0049	0.0046
Echinococcus granulosus	mothers against decapentaplegic 2	0.0031	0.004	0.0037
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.0077	0.0295	1
Trichomonas vaginalis	Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase	0.0033	0.0049	0.1849
Echinococcus multilocularis	ubiquitin carboxyl terminal hydrolase 4	0.0033	0.0049	0.0046
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1408	0.1406

Activities

Activity type	Activity value	Assay description	Source	Reference
ED50 (functional)	= 4.5 mg kg-1	Analgetic activity in sc dosed mouse by hot-plate method	ChEMBL.	915912

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL3273094

Bibliographic References

No literature references available for this target.

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Detailed information for compound 1912397