TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 616.745 | Formula: C39H40N2O5
H donors: 3 H acceptors: 5 LogP: 5.32 Rotable bonds: 13
Rule of 5 violations (Lipinski): 2
SMILES: Oc1ccc(cc1)C[C@@H](C(=O)NC1[C@H](O)Cc2c1cccc2)CC(=O)CN1[C@@H](Cc2ccccc2)C[C@@H](C1=O)Cc1ccccc1
InChi: 1S/C39H40N2O5/c42-33-17-15-28(16-18-33)19-30(38(45)40-37-35-14-8-7-13-29(35)24-36(37)44)23-34(43)25-41-32(21-27-11-5-2-6-12-27)22-31(39(41)46)20-26-9-3-1-4-10-26/h1-18,30-32,36-37,42,44H,19-25H2,(H,40,45)/t30-,31+,32+,36-,37?/m1/s1
InChiKey: LXLGYVVVXVRZPO-LCYCZOHWSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

Species	Target name	Source	Bibliographic reference
Human immunodeficiency virus 1	Human immunodeficiency virus type 1 protease	Starlite/ChEMBL	References

Predicted pathogen targets for this compound

By orthology

Species	Potential target	Known druggable target/s	Ortholog Group
Schistosoma mansoni	intracisternal A-particle retropepsin (A02 family)	Get druggable targets OG5_131408	All targets in OG5_131408

By sequence similarity to non orthologous known druggable targets

Species	Potential target	Known druggable target	Length	Alignment span	Identity
Giardia lamblia	DNA-directed RNA polymerase subunit D	Human immunodeficiency virus type 1 protease	99 aa	90 aa	27.8 %
Entamoeba histolytica	retroviral aspartyl protease domain-containing protein	Human immunodeficiency virus type 1 protease	99 aa	103 aa	31.1 %
Candida albicans	dethiobiotin synthetase	Human immunodeficiency virus type 1 protease	99 aa	90 aa	22.2 %
Candida albicans	dethiobiotin synthetase	Human immunodeficiency virus type 1 protease	99 aa	90 aa	22.2 %
Mycobacterium leprae	Hypothetical protein	Human immunodeficiency virus type 1 protease	99 aa	86 aa	27.9 %
Echinococcus multilocularis	Chromobox protein 3	Human immunodeficiency virus type 1 protease	99 aa	95 aa	28.4 %
Entamoeba histolytica	retroviral aspartyl protease domain-containing protein	Human immunodeficiency virus type 1 protease	99 aa	103 aa	31.1 %
Trypanosoma brucei	variant surface glycoprotein (VSG), putative	Human immunodeficiency virus type 1 protease	99 aa	80 aa	27.5 %

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	hypothetical protein	0.0032	0.0108	0.0114
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	acetylcholine receptor-related	0.0278	0.1276	0.1406
Loa Loa (eye worm)	neuropeptide F receptor	0.0146	0.0649	0.0717
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0262	0.0285
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Echinococcus granulosus	7TM GPCR rhodopsin	0.0146	0.0649	0.0717
Brugia malayi	hypothetical protein	0.0235	0.1073	0.1068
Onchocerca volvulus	Netrin receptor homolog	0.0031	0.0106	0.0332
Echinococcus multilocularis	nibrin	0.001	0.0005	0.0005
Echinococcus multilocularis	serotonin receptor	0.1915	0.9045	1
Schistosoma mansoni	hypothetical protein	0.0146	0.0649	0.0712
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0117	0.6071
Echinococcus multilocularis	tar DNA binding protein	0.0064	0.0262	0.029
Mycobacterium ulcerans	acyl-CoA synthetase	0.0014	0.0024	0.106
Loa Loa (eye worm)	hypothetical protein	0.001	0.0005	0.0005
Schistosoma mansoni	nicotinic acetylcholine receptor alpha	0.0378	0.175	0.1931
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Onchocerca volvulus		0.0014	0.0024	0.0062
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0456	0.0505
Loa Loa (eye worm)	hypothetical protein	0.0053	0.0207	0.0228
Echinococcus multilocularis	neuropeptides capa receptor	0.0146	0.0649	0.0717
Echinococcus multilocularis	uncharacterized sodium dependent transporter	0.0105	0.0456	0.0505
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Schistosoma mansoni	opsin-like receptor	0.0146	0.0649	0.0712
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0108	0.0119
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0656	0.3069	0.3066
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Echinococcus multilocularis	ankyrin repeat and death domain containing protein	0.0031	0.0106	0.0118
Brugia malayi	sulfakinin receptor protein	0.0146	0.0649	0.0644
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0146	0.0649	0.2102
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0146	0.0649	0.0717
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0032	0.0108	0.0119
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.062	0.2898	0.3204
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Mycobacterium ulcerans	acetyl-CoA synthetase	0.0014	0.0024	0.106
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0656	0.3069	0.3066
Loa Loa (eye worm)	G-protein coupled receptor	0.0146	0.0649	0.0717
Mycobacterium tuberculosis	Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0014	0.0024	0.0546
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0146	0.0649	0.0717
Schistosoma mansoni	neuropeptide receptor	0.0146	0.0649	0.0712
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.062	0.2898	0.3204
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Schistosoma mansoni	nAChR subunit	0.0656	0.3069	0.339
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Echinococcus granulosus	tm gpcr rhodopsin	0.0146	0.0649	0.0717
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0105	0.0456	0.05
Onchocerca volvulus		0.0656	0.3069	1
Mycobacterium tuberculosis	Probable peptide synthetase Nrp (peptide synthase)	0.0014	0.0024	0.0546
Echinococcus granulosus	g protein coupled receptor	0.0146	0.0649	0.0717
Echinococcus multilocularis	nicotinic acetylcholine receptor a11 subunit	0.0656	0.3069	0.3393
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0656	0.3069	0.3393
Onchocerca volvulus		0.0146	0.0649	0.2102
Echinococcus granulosus	fmrfamide receptor	0.0146	0.0649	0.0717
Echinococcus granulosus	neuropeptide receptor	0.0146	0.0649	0.0717
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0278	0.1276	0.1272
Onchocerca volvulus		0.0146	0.0649	0.2102
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.01	0.0431	0.0477
Echinococcus multilocularis	glycine receptor subunit beta	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Onchocerca volvulus		0.0146	0.0649	0.2102
Schistosoma mansoni	hypothetical protein	0.0415	0.1927	0.2127
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.0183	1
Onchocerca volvulus		0.0378	0.175	0.5697
Trichomonas vaginalis	conserved hypothetical protein	0.0043	0.0161	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0146	0.0649	0.0717
Schistosoma mansoni	growth hormone secretagogue receptor	0.0146	0.0649	0.0712
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0146	0.0649	0.0712
Echinococcus granulosus	death domain containing protein	0.0031	0.0106	0.0118
Onchocerca volvulus		0.0656	0.3069	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0146	0.0649	0.0717
Echinococcus multilocularis	sodium:chloride dependent neurotransmitter	0.0105	0.0456	0.0505
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Onchocerca volvulus		0.0146	0.0649	0.2102
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0656	0.3069	0.339
Echinococcus granulosus	acetylcholine receptor subunit beta 1	0.0656	0.3069	0.3393
Schistosoma mansoni	chromosome transmission fidelity factor	0.001	0.0005	0.00000014813
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.0183	0.0179
Echinococcus multilocularis	neuropeptide Y receptor	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0048	0.0185	0.0588
Echinococcus multilocularis	g-protein coupled receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.01	0.0432	0.0478
Schistosoma mansoni	myosin xvIII	0.0146	0.0649	0.0712
Brugia malayi	putative neuropeptide receptor	0.0146	0.0649	0.0644
Plasmodium falciparum	acetyl-CoA synthetase, putative	0.0014	0.0024	0.0419
Loa Loa (eye worm)	hypothetical protein	0.005	0.0195	0.0216
Onchocerca volvulus		0.0146	0.0649	0.2102
Brugia malayi	Latrophilin receptor protein 2	0.0032	0.0108	0.0103
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	hypothetical protein	0.0146	0.0649	0.0712
Schistosoma mansoni	nAChR subunit	0.0656	0.3069	0.339
Trypanosoma brucei	acetyl-CoA synthetase, putative	0.0014	0.0024	1
Echinococcus multilocularis	neuropeptide receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus granulosus	neuropeptide s receptor	0.0603	0.2818	0.3116
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0183	0.0203
Toxoplasma gondii	hypothetical protein	0.0105	0.0456	1
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0146	0.0649	0.2102
Brugia malayi	acetylcholine receptor alpha subunit precursor, putative	0.0656	0.3069	0.3066
Schistosoma mansoni	nAChR subunit (ShAR1-beta-like)	0.0656	0.3069	0.339
Schistosoma mansoni	acetylcholine receptor subunit beta	0.0278	0.1276	0.1406
Loa Loa (eye worm)	nicotinic acetylcholine receptor non-alpha subunit	0.0656	0.3069	0.3393
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0378	0.175	0.1746
Echinococcus multilocularis	sodium dependent neurotransmitter transporter	0.0105	0.0456	0.0505
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0183	0.0203
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0456	0.0505
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0048	0.0183	1
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0378	0.175	0.1746
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0456	0.0505
Echinococcus multilocularis	G protein coupled receptor 139	0.0146	0.0649	0.0717
Trichomonas vaginalis	replication factor C large subunit, putative	0.001	0.0005	0.000008579
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus granulosus	replication factor c subunit 1	0.001	0.0005	0.0005
Echinococcus multilocularis	Ankyrin	0.0032	0.0107	0.0118
Brugia malayi	Cation transporter family protein	0.0656	0.3069	0.3066
Brugia malayi	hypothetical protein	0.0278	0.1276	0.1272
Loa Loa (eye worm)	excitatory GABA receptor EXP-1A	0.0656	0.3069	0.3393
Schistosoma mansoni	survival motor neuron protein	0.0048	0.0185	0.0199
Echinococcus multilocularis	GPCR, family 2	0.0032	0.0108	0.0119
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.0183	0.0179
Trypanosoma brucei	long-chain-fatty-acid-CoA ligase, putative	0.0014	0.0024	1
Mycobacterium tuberculosis	P-hydroxybenzoyl-AMP ligase FadD22	0.0014	0.0024	0.0546
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0656	0.3069	0.3066
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0048	0.0183	1
Echinococcus granulosus	nibrin	0.001	0.0005	0.0005
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0117	0.6071
Loa Loa (eye worm)	hypothetical protein	0.0043	0.0161	0.0178
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0656	0.3069	0.3393
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0032	0.0108	0.0119
Schistosoma mansoni	cellular tumor antigen P53	0.005	0.0195	0.0211
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Schistosoma mansoni	hypothetical protein	0.0041	0.0153	0.0165
Echinococcus multilocularis	orexin receptor type 2	0.0146	0.0649	0.0717
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.001	0.0005	0.0005
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Toxoplasma gondii	ATPase, AAA family protein	0.001	0.0005	0.0000029642
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0014	0.0024	0.0546
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0146	0.0649	0.0712
Schistosoma mansoni	sodium/chloride dependent transporter	0.0105	0.0456	0.05
Brugia malayi	AMP-binding enzyme family protein	0.0014	0.0024	0.0019
Echinococcus multilocularis	nuclear factor of activated T cells 5	0.0307	0.1416	0.1566
Loa Loa (eye worm)	melatonin receptor type 1A	0.0146	0.0649	0.0717
Echinococcus multilocularis	protein patched	0.0043	0.0161	0.0178
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0048	0.0183	1
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0656	0.3069	0.3066
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0048	0.0183	1
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0146	0.0649	0.0717
Brugia malayi	Uncoordinated protein 44	0.0031	0.0106	0.0102
Onchocerca volvulus		0.0656	0.3069	1
Loa Loa (eye worm)	hypothetical protein	0.001	0.0005	0.0005
Schistosoma mansoni	neurotransmitter gated ion channel	0.0378	0.175	0.1931
Loa Loa (eye worm)	hypothetical protein	0.001	0.0005	0.0005
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0126	0.0139
Entamoeba histolytica	long-chain-fatty-acid--CoA ligase, putative	0.0014	0.0024	0.0108
Schistosoma mansoni	acetyl-CoA synthetase	0.0014	0.0024	0.0021
Echinococcus granulosus	nAChR subunit	0.0378	0.175	0.1935
Schistosoma mansoni	hypothetical protein	0.0032	0.0108	0.0114
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0146	0.0649	0.0712
Brugia malayi	CHE-14 protein	0.0043	0.0161	0.0156
Loa Loa (eye worm)	hypothetical protein	0.01	0.0432	0.0478
Entamoeba histolytica	Activator 1 140 kDa subunit, putative	0.001	0.0005	0.00000076709
Brugia malayi	acetylcholine receptor, alpha-type subunit unc-38 precursor	0.0656	0.3069	0.3066
Mycobacterium tuberculosis	Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase	0.0014	0.0024	0.0546
Loa Loa (eye worm)	hypothetical protein	0.1412	0.666	0.7364
Echinococcus granulosus	glycine receptor subunit beta	0.0656	0.3069	0.3393
Plasmodium falciparum	amino acid transporter, putative	0.0105	0.0456	1
Onchocerca volvulus		0.0146	0.0649	0.2102
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0456	0.0505
Loa Loa (eye worm)	hypothetical protein	0.001	0.0005	0.0005
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	hypothetical protein	0.0146	0.0649	0.0712
Echinococcus multilocularis	nAChR subunit	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Loa Loa (eye worm)	Sodium:neurotransmitter symporter family protein	0.0105	0.0456	0.0505
Echinococcus granulosus	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0146	0.0649	0.0712
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0146	0.0649	0.2102
Echinococcus multilocularis	netrin receptor unc 5	0.0031	0.0106	0.0118
Echinococcus granulosus	neuropeptides capa receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Onchocerca volvulus		0.0105	0.0456	0.1474
Plasmodium vivax	hypothetical protein, conserved	0.0105	0.0456	1
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0262	0.0285
Onchocerca volvulus		0.0029	0.0096	0.0297
Schistosoma mansoni	nAChR subunit	0.0278	0.1276	0.1406
Plasmodium falciparum	acyl-CoA synthetase	0.0036	0.0126	0.2689
Echinococcus granulosus	hypothetical protein	0.0146	0.0649	0.0717
Brugia malayi	Neuronal acetylcholine receptor protein, alpha-2 chain precursor	0.0278	0.1276	0.1272
Echinococcus granulosus	neuropeptide receptor A26	0.0603	0.2818	0.3116
Brugia malayi	nicotinic acetylcholine receptor beta-1 chain precursor	0.0656	0.3069	0.3066
Echinococcus granulosus	serotonin transporter	0.062	0.2898	0.3204
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus granulosus	sodium:chloride dependent neurotransmitter	0.0105	0.0456	0.0505
Echinococcus granulosus	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0262	0.0285
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Mycobacterium tuberculosis	Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase)	0.0014	0.0024	0.0546
Echinococcus multilocularis	allatostatin A receptor	0.0146	0.0649	0.0717
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Brugia malayi	Serotonin receptor	0.0146	0.0649	0.0644
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0048	0.0183	1
Loa Loa (eye worm)	AMP-binding enzyme family protein	0.0014	0.0024	0.0026
Schistosoma mansoni	hypothetical protein	0.0032	0.0108	0.0114
Plasmodium vivax	acetyl-CoA synthetase, putative	0.0014	0.0024	0.0419
Onchocerca volvulus		0.0656	0.3069	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0048	0.0183	1
Mycobacterium leprae	POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0014	0.0024	0.106
Schistosoma mansoni	hypothetical protein	0.0032	0.0108	0.0114
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0106	0.0118
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0656	0.3069	0.3393
Brugia malayi	larval opioid receptor	0.0146	0.0649	0.0644
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0105	0.0456	0.05
Plasmodium falciparum	transporter, putative	0.0105	0.0456	1
Schistosoma mansoni	transcription factor LCR-F1	0.0072	0.03	0.0327
Toxoplasma gondii	Acetyl-coenzyme A synthetase 2, putative	0.0014	0.0024	0.0419
Brugia malayi	Dopamine receptor protein 2	0.0146	0.0649	0.0644
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	LGC-31 protein	0.0656	0.3069	0.3393
Onchocerca volvulus		0.0278	0.1276	0.4148
Echinococcus granulosus	acetyl coenzyme A synthetase cytoplasmic	0.0014	0.0024	0.0026
Schistosoma mansoni	nAChR subunit (ShAR1-beta2-like)	0.0656	0.3069	0.339
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0146	0.0649	0.0644
Echinococcus granulosus	nicotinic acetylcholine receptor alpha subunit	0.0656	0.3069	0.3393
Echinococcus multilocularis	microtubule associated protein 2	0.0686	0.3212	0.3551
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Brugia malayi	hypothetical protein	0.0278	0.1276	0.1272
Brugia malayi	Death domain containing protein	0.0031	0.0106	0.0102
Echinococcus granulosus	survival motor neuron protein 1	0.0235	0.1073	0.1186
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Brugia malayi	Neurotransmitter-gated ion-channel transmembrane region family protein	0.0656	0.3069	0.3066
Loa Loa (eye worm)	AMP-binding enzyme family protein	0.0014	0.0024	0.0026
Echinococcus multilocularis	sodium and chloride dependent glycine	0.0105	0.0456	0.0505
Brugia malayi	Dopamine receptor protein 1	0.0146	0.0649	0.0644
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Brugia malayi	gamma-aminobutyric-acid receptor beta subunit precursor	0.0656	0.3069	0.3066
Trichomonas vaginalis	antibiotic synthetase, putative	0.0014	0.0024	0.1213
Schistosoma mansoni	neuropeptide receptor	0.0146	0.0649	0.0712
Echinococcus multilocularis	sodium and chloride dependent glycine	0.0105	0.0456	0.0505
Entamoeba histolytica	hypothetical protein	0.0072	0.03	0.1693
Mycobacterium ulcerans	acyl-CoA synthetase	0.0014	0.0024	0.106
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0014	0.0024	0.0546
Entamoeba histolytica	Niemann-Pick C1 protein, putative	0.01	0.0431	0.2445
Loa Loa (eye worm)	GABA receptor subunit	0.0378	0.175	0.1935
Loa Loa (eye worm)	hypothetical protein	0.1915	0.9045	1
Loa Loa (eye worm)	glutamate-gated chloride channel alpha3A subunit	0.0278	0.1276	0.141
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Schistosoma mansoni	hypothetical protein	0.0146	0.0649	0.0712
Mycobacterium ulcerans	O-succinylbenzoic acid--CoA ligase	0.0014	0.0024	0.106
Echinococcus granulosus	sex peptide receptor	0.0146	0.0649	0.0717
Echinococcus granulosus	GPCR family 2	0.0032	0.0108	0.0119
Onchocerca volvulus		0.0146	0.0649	0.2102
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit type	0.0278	0.1276	0.141
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0105	0.0456	0.05
Schistosoma mansoni	neurotransmitter gated ion channel	0.0278	0.1276	0.1406
Echinococcus multilocularis	acetyl coenzyme A synthetase, cytoplasmic	0.0014	0.0024	0.0026
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0378	0.175	0.5697
Echinococcus granulosus	ankyrin repeat and death domain containing protein	0.0031	0.0106	0.0118
Echinococcus granulosus	sodium dependent neurotransmitter transporter	0.0105	0.0456	0.0505
Echinococcus granulosus	glycine receptor subunit beta	0.0656	0.3069	0.3393
Loa Loa (eye worm)	abnormal chemotaxis protein 14	0.0043	0.0161	0.0178
Brugia malayi	Acetylcholine receptor protein, alpha-like chain 1 precursor	0.0278	0.1276	0.1272
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0032	0.0108	0.0103
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0146	0.0649	0.0717
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.0183	0.0179
Schistosoma mansoni	neuropeptide receptor	0.0146	0.0649	0.0712
Trichomonas vaginalis	antibiotic synthetase, putative	0.0014	0.0024	0.1213
Schistosoma mansoni	amine GPCR	0.0146	0.0649	0.0712
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus multilocularis	neuropeptide receptor A26	0.0603	0.2818	0.3116
Echinococcus multilocularis	acetylcholine receptor subunit beta 1	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	niemann-pick C1 (NPC1)	0.0101	0.0439	0.048
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0378	0.175	0.1931
Loa Loa (eye worm)	ACC-1 protein	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Mycobacterium tuberculosis	Phenyloxazoline synthase MbtB (phenyloxazoline synthetase)	0.0014	0.0024	0.0546
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Brugia malayi	latrophilin 2 splice variant baaae	0.0068	0.0282	0.0278
Onchocerca volvulus		0.0146	0.0649	0.2102
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0105	0.0456	0.0452
Onchocerca volvulus		0.0146	0.0649	0.2102
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0048	0.0183	0.1023
Schistosoma mansoni	intracisternal A-particle retropepsin (A02 family)	0.1528	0.7208	0.7969
Echinococcus granulosus	g protein coupled receptor	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0014	0.0024	0.0062
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0048	0.0183	0.1023
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0456	0.0505
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Echinococcus multilocularis	neuropeptide Y receptor	0.0146	0.0649	0.0717
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0146	0.0649	0.0644
Brugia malayi	acetyl-Coenzyme A synthetase 2	0.0014	0.0024	0.0019
Echinococcus granulosus	neuropeptides capa receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	TAR-binding protein	0.0064	0.0262	0.029
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0146	0.0649	0.0717
Schistosoma mansoni	ankyrin 23/unc44	0.0031	0.0106	0.0113
Brugia malayi	nicotinic acetylcholine receptor alpha subunit, putative	0.0656	0.3069	0.3066
Echinococcus granulosus	tm gpcr rhodopsin	0.0146	0.0649	0.0717
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0146	0.0649	0.0717
Echinococcus granulosus	sodium and chloride dependent glycine	0.0105	0.0456	0.0505
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Brugia malayi	excitatory GABA receptor EXP-1A	0.0656	0.3069	0.3066
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0146	0.0649	0.0717
Mycobacterium ulcerans	non-ribosomal peptide synthetase MbtE	0.0014	0.0024	0.106
Onchocerca volvulus		0.0278	0.1276	0.4148
Echinococcus granulosus	gamma aminobutyric acid receptor subunit	0.0278	0.1276	0.141
Brugia malayi	neuropeptide F receptor	0.0146	0.0649	0.0644
Mycobacterium ulcerans	non-ribosomal peptide synthetase MbtF	0.0014	0.0024	0.106
Loa Loa (eye worm)	ACC-1 protein	0.0656	0.3069	0.3393
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0656	0.3069	1
Schistosoma mansoni	hypothetical protein	0.0041	0.0153	0.0165
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0048	0.0183	0.0203
Echinococcus granulosus	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Echinococcus multilocularis	expressed conserved protein	0.0094	0.0403	0.0445
Brugia malayi	GnHR receptor homolog	0.0146	0.0649	0.0644
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0146	0.0649	0.0717
Echinococcus granulosus	Cys loop ligand gated ion channel subunit	0.0278	0.1276	0.141
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0105	0.0456	0.05
Loa Loa (eye worm)	nicotinic acetylcholine receptor alpha subunit	0.0656	0.3069	0.3393
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0032	0.0108	0.0119
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0146	0.0649	0.2102
Brugia malayi	G-protein coupled receptor	0.0146	0.0649	0.0644
Loa Loa (eye worm)	norepinephrine transporter	0.062	0.2898	0.3204
Brugia malayi	hypothetical protein	0.0278	0.1276	0.1272
Echinococcus multilocularis	survival motor neuron protein 1	0.0235	0.1073	0.1186
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Onchocerca volvulus		0.0105	0.0456	0.1474
Brugia malayi	putative neuropeptide receptor NPR1	0.0146	0.0649	0.0644
Echinococcus granulosus	nuclear factor of activated T cells 5	0.0307	0.1416	0.1566
Loa Loa (eye worm)	ligand-Gated ion Channel family member	0.0656	0.3069	0.3393
Loa Loa (eye worm)	CXXC zinc finger family protein	0.0029	0.0096	0.0106
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0656	0.3069	0.3393
Echinococcus granulosus	nicotinic acetylcholine receptor beta 1 subunit	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0032	0.0107	0.0118
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0146	0.0649	0.0644
Brugia malayi	G protein-coupled receptor F59B2.13	0.0146	0.0649	0.0644
Echinococcus granulosus	sodium and chloride dependent glycine	0.0105	0.0456	0.0505
Schistosoma mansoni	cpg binding protein	0.0029	0.0096	0.0101
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus granulosus	G protein coupled receptor 139	0.0146	0.0649	0.0717
Plasmodium vivax	amine transporter, putative	0.0105	0.0456	1
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0126	0.0139
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0126	0.0139
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Schistosoma mansoni	hypothetical protein	0.0072	0.03	0.0327
Schistosoma mansoni	nAChR subunit	0.0656	0.3069	0.339
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Echinococcus multilocularis	neuropeptide s receptor	0.0603	0.2818	0.3116
Echinococcus granulosus	tm gpcr rhodopsin	0.0146	0.0649	0.0717
Brugia malayi	RE15519p	0.0146	0.0649	0.0644
Loa Loa (eye worm)	oxidoreductase	0.0014	0.0024	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0656	0.3069	0.339
Loa Loa (eye worm)	hypothetical protein	0.0235	0.1073	0.1186
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.0183	1
Mycobacterium ulcerans	bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase	0.0014	0.0024	0.106
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Echinococcus granulosus	Protein patched homolog 1	0.0043	0.0161	0.0178
Echinococcus granulosus	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0105	0.0456	1
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0036	0.0126	0.6801
Onchocerca volvulus		0.0146	0.0649	0.2102
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0146	0.0649	0.0712
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Mycobacterium ulcerans	acyl-CoA synthetase	0.0014	0.0024	0.106
Echinococcus multilocularis	g protein coupled receptor	0.0146	0.0649	0.0717
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0146	0.0649	0.0712
Echinococcus granulosus	Ankyrin	0.0032	0.0107	0.0118
Loa Loa (eye worm)	RNA binding protein	0.0064	0.0262	0.029
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Schistosoma mansoni	cpg binding protein	0.0031	0.0103	0.0109
Loa Loa (eye worm)	hypothetical protein	0.0068	0.0282	0.0312
Mycobacterium leprae	Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase)	0.0014	0.0024	0.106
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Schistosoma mansoni	amine GPCR	0.0146	0.0649	0.0712
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.1412	0.666	0.6659
Brugia malayi	hypothetical protein	0.0278	0.1276	0.1272
Echinococcus granulosus	somatostatin receptor	0.0146	0.0649	0.0717
Brugia malayi	CXXC zinc finger family protein	0.0029	0.0096	0.0091
Echinococcus multilocularis	Niemann Pick C1 protein	0.0143	0.0635	0.0702
Brugia malayi	Sodium:neurotransmitter symporter family protein 1, putative	0.0105	0.0456	0.0452
Echinococcus multilocularis	tumor protein p63	0.0343	0.1585	0.1752
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Echinococcus multilocularis	nicotinic acetylcholine receptor subunit alpha 8	0.0656	0.3069	0.3393
Echinococcus multilocularis	dro:myosuppressin receptor	0.0146	0.0649	0.0717
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Trypanosoma cruzi	long-chain-fatty-acid-CoA ligase, putative	0.0014	0.0024	1
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	hypothetical protein	0.0031	0.0106	0.0113
Schistosoma mansoni	cpg binding protein	0.0031	0.0103	0.0109
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0278	0.1276	0.1272
Mycobacterium ulcerans	long-chain-acyl-CoA synthetase	0.0014	0.0024	0.106
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	biogenic amine (5HT) receptor	0.1915	0.9045	1
Echinococcus granulosus	dro:myosuppressin receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0105	0.0456	0.0452
Echinococcus granulosus	uncharacterized sodium dependent transporter	0.0105	0.0456	0.0505
Trypanosoma cruzi	acetyl-CoA synthetase, putative	0.0014	0.0024	1
Loa Loa (eye worm)	hypothetical protein	0.062	0.2898	0.3204
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0656	0.3069	0.3066
Chlamydia trachomatis	acylglycerophosphoethanolamine acyltransferase	0.0036	0.0126	0.2689
Mycobacterium tuberculosis	Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0014	0.0024	0.0546
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.0183	1
Loa Loa (eye worm)	neuronal acetylcholine receptor protein	0.0278	0.1276	0.141
Schistosoma mansoni	nAChR subunit	0.0656	0.3069	0.339
Echinococcus multilocularis	Niemann Pick C1 protein	0.01	0.0431	0.0477
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Mycobacterium ulcerans	phenyloxazoline synthase MbtB	0.0014	0.0024	0.106
Entamoeba histolytica	hypothetical protein	0.0072	0.03	0.1693
Schistosoma mansoni	nAChR subunit	0.0656	0.3069	0.339
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Loa Loa (eye worm)	acetylcholine receptor alpha subunit	0.0656	0.3069	0.3393
Echinococcus multilocularis	fmrfamide receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	neuropeptide F receptor	0.0146	0.0649	0.0717
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0656	0.3069	0.3066
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0278	0.1276	0.1272
Mycobacterium ulcerans	acyl-CoA synthetase	0.0014	0.0024	0.106
Echinococcus multilocularis	cpg binding protein	0.0031	0.0103	0.0114
Echinococcus multilocularis	dnaJ subfamily B	0.0415	0.1927	0.2131
Toxoplasma gondii	propionate-CoA ligase	0.0014	0.0024	0.0419
Schistosoma mansoni	retinoblastoma-binding protein 4 (rbbp4)	0.0032	0.0107	0.0113
Onchocerca volvulus		0.0146	0.0649	0.2102
Brugia malayi	ORL1-like opioid receptor	0.0146	0.0649	0.0644
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Echinococcus multilocularis	nicotinic acetylcholine receptor beta 1 subunit	0.0656	0.3069	0.3393
Brugia malayi	follicle stimulating hormone receptor	0.0146	0.0649	0.0644
Schistosoma mansoni	amine GPCR	0.0146	0.0649	0.0712
Schistosoma mansoni	neuropeptide F-like receptor	0.0146	0.0649	0.0712
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0146	0.0649	0.0717
Schistosoma mansoni	opsin-like receptor	0.0146	0.0649	0.0712
Echinococcus granulosus	7tm_1 domain containing protein	0.0146	0.0649	0.0717
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.062	0.2898	0.2895
Brugia malayi	Cation transporter family protein	0.0656	0.3069	0.3066
Schistosoma mansoni	Cys-loop ligand gated ion channel subunit	0.0656	0.3069	0.339
Brugia malayi	Protein kinase domain containing protein	0.0031	0.0106	0.0102
Echinococcus granulosus	neuronal acetylcholine receptor subunit alpha 4	0.0656	0.3069	0.3393
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0146	0.0649	0.0712
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Echinococcus multilocularis	somatostatin receptor	0.0146	0.0649	0.0717
Schistosoma mansoni	hypothetical protein	0.0041	0.0153	0.0165
Treponema pallidum	sodium- and chloride- dependent transporter	0.062	0.2898	1
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0055	0.0219	0.4752
Schistosoma mansoni	hypothetical protein	0.0048	0.0185	0.0199
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Brugia malayi	glutamate-gated chloride channel alpha3A subunit, putative	0.0378	0.175	0.1746
Echinococcus multilocularis	nicotinic acetylcholine receptor alpha subunit	0.0656	0.3069	0.3393
Brugia malayi	RNA recognition motif domain containing protein	0.0064	0.0262	0.0258
Echinococcus multilocularis	glycine receptor subunit alpha 1	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Brugia malayi	AKH receptor	0.0146	0.0649	0.0644
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0105	0.0456	0.05
Brugia malayi	TAR-binding protein	0.0064	0.0262	0.0258
Brugia malayi	Cation transporter family protein	0.0656	0.3069	0.3066
Onchocerca volvulus		0.0146	0.0649	0.2102
Echinococcus granulosus	neuropeptide Y receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Loa Loa (eye worm)	serotonin transporter b	0.062	0.2898	0.3204
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0456	0.0505
Schistosoma mansoni	neuropeptide f receptor 76f	0.0146	0.0649	0.0712
Brugia malayi	RNA binding protein	0.0064	0.0262	0.0258
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0105	0.0456	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0117	0.6071
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0024	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Echinococcus granulosus	sterol regulatory element binding protein	0.0043	0.0161	0.0178
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0014	0.0024	0.106
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0146	0.0649	0.0712
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0117	0.6071
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0072	0.03	0.0332
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0024	0.0026
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0032	0.0108	0.0119
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0146	0.0649	0.0712
Echinococcus multilocularis	fmrfamide receptor	0.0146	0.0649	0.0717
Schistosoma mansoni	amine GPCR	0.0146	0.0649	0.0712
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Echinococcus granulosus	tar DNA binding protein	0.0064	0.0262	0.029
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0146	0.0649	0.0717
Brugia malayi	Hypothetical glycine receptor like protein T20B12.9 in chromosome III	0.0378	0.175	0.1746
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.0183	1
Toxoplasma gondii	hypothetical protein	0.0105	0.0456	1
Echinococcus granulosus	nicotinic acetylcholine receptor subunit type	0.0656	0.3069	0.3393
Loa Loa (eye worm)	Sodium:neurotransmitter symporter family protein	0.0105	0.0456	0.0505
Mycobacterium ulcerans	acyl-CoA synthetase	0.0014	0.0024	0.106
Echinococcus granulosus	biogenic amine 5HT receptor	0.0146	0.0649	0.0717
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.0183	1
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Schistosoma mansoni	sodium/chloride dependent transporter	0.062	0.2898	0.32
Echinococcus multilocularis	sterol regulatory element binding protein	0.0043	0.0161	0.0178
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus granulosus	g-protein coupled receptor	0.0146	0.0649	0.0717
Echinococcus multilocularis	gamma aminobutyric acid receptor subunit	0.0278	0.1276	0.141
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	sodium-dependent amino acid transporter	0.0105	0.0456	0.05
Brugia malayi	AMP-binding enzyme family protein	0.0014	0.0024	0.0019
Entamoeba histolytica	hypothetical protein	0.0378	0.175	1
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0278	0.1276	0.141
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	patched 1	0.0043	0.0161	0.0173
Mycobacterium ulcerans	hypothetical protein	0.0048	0.0183	1
Brugia malayi	G protein-coupled receptor	0.0146	0.0649	0.0644
Entamoeba histolytica	hypothetical protein	0.0072	0.03	0.1693
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Brugia malayi	AMP-binding enzyme family protein	0.0014	0.0024	0.0019
Echinococcus granulosus	neuropeptide Y receptor	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0105	0.0456	0.1474
Toxoplasma gondii	AMP-binding enzyme domain-containing protein	0.0014	0.0024	0.0419
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0656	0.3069	0.3066
Mycobacterium ulcerans	peptide synthetase Nrp (peptide synthase)	0.0014	0.0024	0.106
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Schistosoma mansoni	microtubule-associated protein tau	0.0686	0.3212	0.3548
Echinococcus multilocularis	Cys loop ligand gated ion channel subunit	0.0656	0.3069	0.3393
Brugia malayi	AMP-binding enzyme family protein	0.0014	0.0024	0.0019
Echinococcus multilocularis	glycine receptor subunit beta	0.0656	0.3069	0.3393
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0146	0.0649	0.0712
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0262	0.0285
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0146	0.0649	0.0644
Echinococcus granulosus	uncharacterized sodium dependent transporter	0.0105	0.0456	0.0505
Echinococcus granulosus	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Echinococcus granulosus	nicotinic acetylcholine receptor subunit alpha 8	0.0656	0.3069	0.3393
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0146	0.0649	0.0712
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0048	0.0183	1
Schistosoma mansoni	biogenic amine receptor	0.0146	0.0649	0.0712
Schistosoma mansoni	adenoreceptor	0.0146	0.0649	0.0712
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0146	0.0649	0.0712
Schistosoma mansoni	family A2 unassigned peptidase (A02 family)	0.0278	0.1276	0.1406
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0105	0.0456	0.05
Echinococcus granulosus	glycine receptor subunit alpha 1	0.0656	0.3069	0.3393
Schistosoma mansoni	neuropeptide receptor	0.0146	0.0649	0.0712
Echinococcus granulosus	nAChR subunit	0.0656	0.3069	0.3393
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0105	0.0456	0.0452
Loa Loa (eye worm)	hypothetical protein	0.0105	0.0456	0.0505
Entamoeba histolytica	acyl-coA synthetase, putative	0.0048	0.0183	0.1023
Entamoeba histolytica	hypothetical protein	0.0072	0.03	0.1693
Echinococcus granulosus	netrin receptor unc 5	0.0031	0.0106	0.0118
Brugia malayi	Melatonin receptor type 1A	0.0146	0.0649	0.0644
Brugia malayi	Iron-sulfur cluster assembly accessory protein	0.0048	0.0185	0.018
Trypanosoma cruzi	long-chain-fatty-acid-CoA ligase, putative	0.0014	0.0024	1
Loa Loa (eye worm)	TYRA-2 protein	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0146	0.0649	0.2102
Loa Loa (eye worm)	solute carrier family 6 member 4	0.062	0.2898	0.3204
Mycobacterium tuberculosis	Peptide synthetase MbtF (peptide synthase)	0.0014	0.0024	0.0546
Echinococcus multilocularis	neuropeptides capa receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Mycobacterium ulcerans	acyl-CoA synthetase	0.0014	0.0024	0.106
Echinococcus multilocularis	g protein coupled receptor	0.0146	0.0649	0.0717
Brugia malayi	hypothetical protein	0.0278	0.1276	0.1272
Echinococcus granulosus	dnaJ subfamily B	0.0415	0.1927	0.2131
Brugia malayi	hypothetical protein	0.0072	0.03	0.0296
Onchocerca volvulus		0.062	0.2898	0.9442
Echinococcus multilocularis	protein dispatched 1	0.0049	0.0189	0.0209
Echinococcus granulosus	microtubule associated protein 2	0.0686	0.3212	0.3551
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0036	0.0126	0.6617
Echinococcus granulosus	tumor protein p63	0.0343	0.1585	0.1752
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.0183	1
Echinococcus multilocularis	serotonin transporter	0.062	0.2898	0.3204
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0072	0.03	0.0332
Onchocerca volvulus		0.0048	0.0183	0.0583
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0146	0.0649	0.0717
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0105	0.0456	1
Schistosoma mansoni	tar DNA-binding protein	0.0064	0.0262	0.0285
Echinococcus granulosus	Niemann Pick C1 protein	0.01	0.0431	0.0477
Brugia malayi	oxidoreductase, short chain dehydrogenase/reductase family protein	0.0014	0.0024	0.0019
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.01	0.0432	0.0428
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Echinococcus granulosus	g protein coupled receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0146	0.0649	0.0717
Onchocerca volvulus		0.005	0.0195	0.0623
Onchocerca volvulus		0.0146	0.0649	0.2102
Schistosoma mansoni	nAChR subunit	0.0656	0.3069	0.339
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0105	0.0456	0.05
Brugia malayi	Immunoglobulin I-set domain containing protein	0.0031	0.0106	0.0102
Schistosoma mansoni	biogenic amine receptor	0.0146	0.0649	0.0712
Onchocerca volvulus		0.0014	0.0024	0.0062
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0146	0.0649	0.0717
Wolbachia endosymbiont of Brugia malayi	NAD-dependent DNA ligase, Lig	0.001	0.0005	0.5
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0146	0.0649	0.0717
Echinococcus multilocularis	neuronal acetylcholine receptor subunit alpha 4	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0126	0.0139
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0146	0.0649	0.0712
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Chlamydia trachomatis	Ssodium-dependent amino acid transporter	0.0105	0.0456	1
Brugia malayi	Dopamine receptor	0.0146	0.0649	0.0644
Echinococcus granulosus	Niemann Pick C1 protein	0.0143	0.0635	0.0702
Schistosoma mansoni	hypothetical protein	0.0041	0.0153	0.0165
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0278	0.1276	0.1272
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0146	0.0649	0.0717
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0146	0.0649	0.0712
Loa Loa (eye worm)	hypothetical protein	0.0278	0.1276	0.141
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Schistosoma mansoni	sodium/chloride dependent transporter	0.0105	0.0456	0.05
Echinococcus granulosus	biogenic amine 5HT receptor	0.1915	0.9045	1
Brugia malayi	neuropeptide F receptor	0.0146	0.0649	0.0644
Schistosoma mansoni	nAChR subunit (ShAR1-alpha-like)	0.0656	0.3069	0.339
Trypanosoma cruzi	acetyl-CoA synthetase, putative	0.0014	0.0024	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0146	0.0649	0.0717
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0656	0.3069	0.3066
Loa Loa (eye worm)	hypothetical protein	0.0378	0.175	0.1935
Mycobacterium ulcerans	acyl-CoA synthetase	0.0014	0.0024	0.106
Schistosoma mansoni	opsin-like receptor	0.0146	0.0649	0.0712
Echinococcus multilocularis	serotonin receptor	0.1915	0.9045	1
Schistosoma mansoni	nAChR subunit	0.0278	0.1276	0.1406
Echinococcus granulosus	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Schistosoma mansoni	nAChR subunit	0.0656	0.3069	0.339
Trichomonas vaginalis	chromosome transmission fidelity factor, putative	0.001	0.0005	0.000008579
Onchocerca volvulus	Putative nachr subunit	0.0656	0.3069	1
Brugia malayi	hypothetical protein	0.0105	0.0456	0.0452
Loa Loa (eye worm)	hypothetical protein	0.1412	0.666	0.7364
Schistosoma mansoni	neurotransmitter gated ion channel	0.0278	0.1276	0.1406
Echinococcus multilocularis	neuropeptide receptor	0.0146	0.0649	0.0717
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.062	0.2898	0.32
Onchocerca volvulus		0.0146	0.0649	0.2102
Mycobacterium tuberculosis	Peptide synthetase MbtE (peptide synthase)	0.0014	0.0024	0.0546
Schistosoma mansoni	histamine h1 receptor	0.0146	0.0649	0.0712
Schistosoma mansoni	amine GPCR	0.0146	0.0649	0.0712
Echinococcus granulosus	nicotinic acetylcholine receptor a11 subunit	0.0656	0.3069	0.3393
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Echinococcus multilocularis	nAChR subunit	0.0378	0.175	0.1935
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	G-protein coupled receptor	0.0146	0.0649	0.0717
Mycobacterium ulcerans	acyl-CoA synthetase	0.0014	0.0024	0.106
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0032	0.0108	0.0119
Loa Loa (eye worm)	RNA recognition domain-containing protein domain-containing protein	0.0064	0.0262	0.029
Loa Loa (eye worm)	hypothetical protein	0.1915	0.9045	1
Echinococcus multilocularis	sex peptide receptor	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0146	0.0649	0.0717
Echinococcus granulosus	expressed conserved protein	0.0094	0.0403	0.0445
Onchocerca volvulus		0.0656	0.3069	1
Echinococcus granulosus	neuropeptide receptor	0.0146	0.0649	0.0717
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0146	0.0649	0.0717
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0062	0.0251	0.0272
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0146	0.0649	0.0717
Onchocerca volvulus		0.0278	0.1276	0.4148
Echinococcus multilocularis	atpase aaa+ type core atpase aaa type core	0.0823	0.3863	0.4271
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0146	0.0649	0.0712
Schistosoma mansoni	netrin receptor unc5	0.0031	0.0106	0.0113
Brugia malayi	Neurotransmitter-gated ion-channel ligand binding domain containing protein	0.0656	0.3069	0.3066
Schistosoma mansoni	neuropeptide F-like receptor	0.0146	0.0649	0.0712
Mycobacterium leprae	POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE)	0.0014	0.0024	0.106
Echinococcus granulosus	allatostatin A receptor	0.0146	0.0649	0.0717
Trichomonas vaginalis	chromosome transmission fidelity factor, putative	0.001	0.0005	0.000008579
Echinococcus multilocularis	replication factor c subunit 1	0.001	0.0005	0.0005
Echinococcus granulosus	neuropeptide FF receptor 2	0.0146	0.0649	0.0717
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0126	0.0139
Schistosoma mansoni	hypothetical protein	0.0068	0.0282	0.0307
Loa Loa (eye worm)	hypothetical protein	0.0656	0.3069	0.3393
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.1412	0.666	0.7362
Brugia malayi	hypothetical protein	0.0146	0.0649	0.0644
Brugia malayi	acetylcholine receptor protein, alpha-like chain, putative	0.0656	0.3069	0.3066
Echinococcus granulosus	orexin receptor type 2	0.0146	0.0649	0.0717
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0048	0.0183	1
Loa Loa (eye worm)	immunoglobulin I-set domain-containing protein	0.0031	0.0106	0.0118
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0146	0.0649	0.0644
Brugia malayi	Calcitonin receptor-like protein seb-1	0.01	0.0432	0.0428
Echinococcus multilocularis	g protein coupled receptor	0.0146	0.0649	0.0717
Giardia lamblia	Replication factor C, subunit 1	0.001	0.0005	0.5
Plasmodium vivax	acyl-CoA synthetase, putative	0.0036	0.0126	0.2689
Brugia malayi	Niemann-Pick C1 protein precursor	0.01	0.0431	0.0427
Echinococcus granulosus	serotonin receptor	0.0146	0.0649	0.0717
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0105	0.0456	0.05
Loa Loa (eye worm)	hypothetical protein	0.001	0.0005	0.0005
Loa Loa (eye worm)	acetylcholine receptor protein	0.0278	0.1276	0.141
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0146	0.0649	0.0717
Schistosoma mansoni	biogenic amine receptor	0.0146	0.0649	0.0712
Brugia malayi	G-protein coupled receptor	0.0146	0.0649	0.0644
Onchocerca volvulus		0.0014	0.0024	0.0062
Echinococcus granulosus	cpg binding protein	0.0031	0.0103	0.0114

Activities

Activity type	Activity value	Assay description	Source	Reference
IC50 (functional)	= 0.32 uM	Antiviral inhibitory concentration against human immunodeficiency virus type 1 in MT-4 cell culture	ChEMBL.	15582415
IC50 (functional)	= 0.32 uM	Antiviral inhibitory concentration against human immunodeficiency virus type 1 in MT-4 cell culture	ChEMBL.	15582415
Ki (binding)	= 0.06 nM	Inhibition constant against HIV Protease	ChEMBL.	15582415
Ki (binding)	= 0.06 nM	Inhibition constant against HIV Protease	ChEMBL.	15582415

Phenotypes

Whole-cell/tissue/organism interactions

Species name	Source	Reference	Is orphan
Homo sapiens	ChEMBL23	15582415

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

ChEMBL: CHEMBL361110

Bibliographic References

1 literature reference was collected for this gene.

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Detailed information for compound 319524