Detailed information for compound 435908

Basic information

Technical information
  • TDR Targets ID: 435908
  • Name: 2-(4-methoxyanilino)-5-(4-methoxybenzoyl)-4-m ethylthiophene-3-carboxylic acid
  • MW: 397.444 | Formula: C21H19NO5S
  • H donors: 2 H acceptors: 3 LogP: 5.54 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)Nc1sc(c(c1C(=O)O)C)C(=O)c1ccc(cc1)OC
  • InChi: 1S/C21H19NO5S/c1-12-17(21(24)25)20(22-14-6-10-16(27-3)11-7-14)28-19(12)18(23)13-4-8-15(26-2)9-5-13/h4-11,22H,1-3H3,(H,24,25)
  • InChiKey: MTMLWTYDAOXDHF-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(4-methoxyanilino)-5-(4-methoxybenzoyl)-4-methyl-thiophene-3-carboxylic acid
  • 2-(4-methoxyanilino)-5-[(4-methoxyphenyl)-oxomethyl]-4-methyl-3-thiophenecarboxylic acid
  • 2-[(4-methoxyphenyl)amino]-5-(4-methoxyphenyl)carbonyl-4-methyl-thiophene-3-carboxylic acid
  • 4-methyl-2-(p-anisidino)-5-p-anisoyl-3-thenoic acid

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) hypothetical protein 0.0108 0.2025 0.2025
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Leishmania major cathepsin L-like protease 0.0076 0.1346 1
Schistosoma mansoni hypothetical protein 0.0042 0.0631 0.0631
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0043
Brugia malayi Nuclear hormone receptor-like 1 0.0108 0.2025 0.2025
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0205 0.4058 0.4058
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Loa Loa (eye worm) intermediate filament protein 0.0025 0.0281 0.0281
Schistosoma mansoni jumonji domain containing protein 0.0047 0.0745 0.0745
Brugia malayi hypothetical protein 0.0326 0.6605 0.6605
Leishmania major 4-coumarate:coa ligase-like protein 0.0041 0.0606 0.4506
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0014 0.0043 0.0318
Onchocerca volvulus 0.0073 0.1285 0.1285
Mycobacterium ulcerans hypothetical protein 0.0041 0.0606 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0076 0.1346 0.1346
Echinococcus multilocularis lysine specific demethylase 5A 0.0047 0.0745 0.0745
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Echinococcus multilocularis cathepsin b 0.0014 0.0043 0.0043
Loa Loa (eye worm) nuclear hormone receptor 0.0097 0.1781 0.1781
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0606 0.0606
Toxoplasma gondii LsmAD domain-containing protein 0.0024 0.0246 0.183
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.007 0.1215 0.1215
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0354 0.5844
Schistosoma mansoni cathepsin B (C01 family) 0.0014 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0.0043 0.0318
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0.0043 0.0318
Onchocerca volvulus Peroxidase homolog 0.0488 1 1
Schistosoma mansoni cathepsin F (C01 family) 0.0076 0.1346 0.1346
Brugia malayi hypothetical protein 0.0015 0.007 0.007
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.006 0.1 0.1
Schistosoma mansoni tar DNA-binding protein 0.006 0.1 0.1
Trypanosoma brucei cysteine peptidase C (CPC) 0.0014 0.0043 0.0318
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0041 0.0606 1
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0041 0.0606 1
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Schistosoma mansoni cell polarity protein 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0205 0.4058 0.4058
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Entamoeba histolytica acyl-coA synthetase, putative 0.0041 0.0606 0.4506
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Onchocerca volvulus 0.0076 0.1346 0.1346
Brugia malayi hypothetical protein 0.007 0.1215 0.1215
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Brugia malayi nuclear hormone receptor 0.0205 0.4058 0.4058
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0097 0.1781 0.1781
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.1346 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0014 0.0043 0.0318
Brugia malayi jmjC domain containing protein 0.0013 0.0014 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Leishmania major cathepsin L-like protease 0.0076 0.1346 1
Plasmodium vivax JmjC domain containing protein 0.0013 0.0014 0.0104
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Entamoeba histolytica cysteine protease, putative 0.0014 0.0043 0.0318
Loa Loa (eye worm) steroid hormone receptor 0.0205 0.4058 0.4058
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0205 0.4058 0.4058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0817 0.6075
Schistosoma mansoni hypothetical protein 0.0042 0.0631 0.0631
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0205 0.4058 0.4058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0051 0.0817 0.6075
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Echinococcus granulosus neurogenic locus protein delta 0.0073 0.1285 0.1285
Brugia malayi cathepsin L-like precursor 0.0051 0.0817 0.0817
Onchocerca volvulus 0.0023 0.0222 0.0222
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0027 0.0321 0.2388
Onchocerca volvulus Peroxidase homolog 0.0488 1 1
Onchocerca volvulus 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0043
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0097 0.1781 0.1781
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0205 0.4058 0.4058
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0076 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Brugia malayi hypothetical protein 0.0108 0.2025 0.2025
Echinococcus granulosus intermediate filament protein 0.0025 0.0281 0.0281
Brugia malayi Animal haem peroxidase family protein 0.0488 1 1
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0014 0.0043 0.0043
Echinococcus multilocularis fibropellin Ia 0.0073 0.1285 0.1285
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Echinococcus granulosus protein jagged 1 0.0073 0.1285 0.1285
Schistosoma mansoni notch 0.0073 0.1285 0.1285
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0081 0.1452 0.1452
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0081 0.1452 0.1452
Schistosoma mansoni hypothetical protein 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Schistosoma mansoni lamin 0.0025 0.0281 0.0281
Schistosoma mansoni cathepsin F (C01 family) 0.0076 0.1346 0.1346
Echinococcus granulosus nuclear receptor nhr 48 0.0097 0.1781 0.1781
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Onchocerca volvulus Protein ultraspiracle homolog 0.0205 0.4058 0.4058
Echinococcus multilocularis lamin 0.0025 0.0281 0.0281
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0081 0.1452 0.1452
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0081 0.1452 0.1452
Toxoplasma gondii cathepsin CPC2 0.0014 0.0043 0.0318
Brugia malayi Intermediate filament tail domain containing protein 0.0025 0.0281 0.0281
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0014 0.0043 0.0043
Onchocerca volvulus 0.0025 0.0281 0.0281
Leishmania major cathepsin L-like protease 0.0076 0.1346 1
Brugia malayi Transmembrane cell adhesion receptor mua-3 precursor, putative 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0108 0.2025 0.2025
Loa Loa (eye worm) hypothetical protein 0.0205 0.4058 0.4058
Schistosoma mansoni notch 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0025 0.0276 0.0276
Brugia malayi Cathepsin L-like precursor 0.0076 0.1346 0.1346
Trypanosoma cruzi cruzipain precursor, putative 0.0025 0.0276 0.2052
Onchocerca volvulus 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0031 0.0389 0.0389
Toxoplasma gondii EGF family domain-containing protein 0.0073 0.1285 0.9549
Schistosoma mansoni intermediate filament proteins 0.0025 0.0281 0.0281
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Echinococcus granulosus thyroid hormone receptor alpha 0.0097 0.1781 0.1781
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0042 0.0631 0.0631
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0205 0.4058 0.4058
Onchocerca volvulus Peroxidasin homolog 0.0488 1 1
Onchocerca volvulus 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0041 0.0606 0.0606
Schistosoma mansoni cpg binding protein 0.0024 0.025 0.025
Echinococcus multilocularis cysteine protease 0.0076 0.1346 0.1346
Brugia malayi Isocitrate dehydrogenase 0.0027 0.0321 0.0321
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0043 0.0318
Echinococcus multilocularis ecdysone induced protein 78C 0.0205 0.4058 0.4058
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Schistosoma mansoni septate junction protein 0.0073 0.1285 0.1285
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0047 0.0745 0.0745
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0097 0.1781 0.1781
Schistosoma mansoni nuclear hormone receptor 0.0097 0.1781 0.1781
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0014 0.0014
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0246 0.183
Onchocerca volvulus 0.0073 0.1285 0.1285
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Plasmodium falciparum serine repeat antigen 9 0.0014 0.0043 0.0318
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0205 0.4058 0.4058
Echinococcus granulosus ecdysone induced protein 78C 0.0205 0.4058 0.4058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0043 0.0318
Onchocerca volvulus 0.0076 0.1346 0.1346
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0205 0.4058 0.4058
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0014 0.0043 0.0318
Brugia malayi latrophilin 2 splice variant baaae 0.0091 0.1655 0.1655
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0014 0.0043 0.0043
Leishmania major 4-coumarate:coa ligase-like protein 0.0041 0.0606 0.4506
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0205 0.4058 0.4058
Entamoeba histolytica hypothetical protein 0.007 0.1215 0.9033
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Schistosoma mansoni notch 0.0073 0.1285 0.1285
Schistosoma mansoni coup transcription factor 0.0205 0.4058 0.4058
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Schistosoma mansoni nuclear receptor 0.0097 0.1781 0.1781
Loa Loa (eye worm) notch protein 0.0073 0.1285 0.1285
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0027 0.0321 0.0321
Echinococcus multilocularis notch 0.0073 0.1285 0.1285
Echinococcus granulosus cathepsin l cysteine peptidase 0.0076 0.1346 0.1346
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0205 0.4058 0.4058
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0205 0.4058 0.4058
Schistosoma mansoni cathepsin S (C01 family) 0.0014 0.0043 0.0043
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0014 0.0043 0.0043
Schistosoma mansoni jumonji domain containing protein 0.0013 0.0014 0.0014
Schistosoma mansoni laminin gamma-3 chain 0.0073 0.1285 0.1285
Brugia malayi Papain family cysteine protease containing protein 0.0039 0.0571 0.0571
Onchocerca volvulus 0.0097 0.1781 0.1781
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0014 0.0043 0.0318
Schistosoma mansoni tar DNA-binding protein 0.006 0.1 0.1
Echinococcus granulosus lamin dm0 0.0025 0.0281 0.0281
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0031 0.0389 0.6421
Plasmodium vivax vivapain-2 0.0076 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0043
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Brugia malayi Calcitonin receptor-like protein seb-1 0.0133 0.2538 0.2538
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0027 0.0321 0.2388
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0571 0.4243
Plasmodium falciparum JmjC domain-containing protein, putative 0.0013 0.0014 0.0104
Echinococcus multilocularis jumonji domain containing 1A 0.0013 0.0014 0.0014
Schistosoma mansoni cpg binding protein 0.0024 0.025 0.025
Schistosoma mansoni hypothetical protein 0.0073 0.1285 0.1285
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0133 0.2538 0.2538
Brugia malayi Cadherin domain containing protein 0.0073 0.1285 0.1285
Loa Loa (eye worm) DR-78 0.0097 0.1781 0.1781
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0205 0.4058 0.4058
Schistosoma mansoni cpg binding protein 0.0023 0.0222 0.0222
Echinococcus granulosus peroxidasin 0.0488 1 1
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0027 0.0321 0.53
Brugia malayi Calcium binding EGF domain containing protein 0.0073 0.1285 0.1285
Brugia malayi RNA binding protein 0.006 0.1 0.1
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0205 0.4058 0.4058
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Echinococcus multilocularis cathepsin b 0.0014 0.0043 0.0043
Brugia malayi Animal haem peroxidase family protein 0.0488 1 1
Onchocerca volvulus 0.0014 0.0043 0.0043
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0205 0.4058 0.4058
Echinococcus multilocularis neural cadherin 0.0073 0.1285 0.1285
Onchocerca volvulus Bile acid receptor homolog 0.0205 0.4058 0.4058
Loa Loa (eye worm) CXXC zinc finger family protein 0.0023 0.0222 0.0222
Toxoplasma gondii cathepsin B 0.0014 0.0043 0.0318
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Schistosoma mansoni cathepsin F (C01 family) 0.0051 0.0817 0.0817
Loa Loa (eye worm) hypothetical protein 0.0025 0.0281 0.0281
Brugia malayi EGF-like domain containing protein 0.0073 0.1285 0.1285
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0014 0.0043 0.0318
Echinococcus granulosus cathepsin L cysteine protease 0.0039 0.0571 0.0571
Plasmodium falciparum serine repeat antigen 1 0.0014 0.0043 0.0318
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0205 0.4058 0.4058
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0205 0.4058 0.4058
Echinococcus multilocularis geminin 0.0293 0.5897 0.5897
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Echinococcus multilocularis neurogenic locus notch protein 0.0073 0.1285 0.1285
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Schistosoma mansoni tar DNA-binding protein 0.006 0.1 0.1
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0014 0.0041 0.0041
Echinococcus multilocularis muscleblind protein 1 0.0147 0.2843 0.2843
Brugia malayi ecdysone receptor 0.0097 0.1781 0.1781
Entamoeba histolytica hypothetical protein 0.007 0.1215 0.9033
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0014 0.0014
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0097 0.1781 0.1781
Plasmodium vivax vivapain-3 0.0039 0.0571 0.4243
Brugia malayi Delta serrate ligand family protein 0.0073 0.1285 0.1285
Plasmodium falciparum serine repeat antigen 5 0.0014 0.0043 0.0318
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Brugia malayi Cathepsin L-like cysteine proteinase 0.0051 0.0817 0.0817
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0097 0.1781 0.1781
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0012 0.0005 0.0005
Brugia malayi nuclear hormone receptor family member odr-7 0.0097 0.1781 0.1781
Brugia malayi Animal haem peroxidase family protein 0.0488 1 1
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0043 0.0043
Brugia malayi Peroxidasin 0.0488 1 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0205 0.4058 0.4058
Echinococcus granulosus cathepsin L 0.0039 0.0571 0.0571
Brugia malayi EGF-like domain containing protein 0.0073 0.1285 0.1285
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0205 0.4058 0.4058
Brugia malayi conserved hypotetical protein 0.0097 0.1781 0.1781
Echinococcus multilocularis protein jagged 1 0.0073 0.1285 0.1285
Brugia malayi cathepsin Z-like cysteine proteinase 0.0014 0.0043 0.0043
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Leishmania major cathepsin L-like protease 0.0076 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0043
Entamoeba histolytica hypothetical protein 0.007 0.1215 0.9033
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0571 0.4243
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0013 0.0014 0.0104
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0081 0.1452 0.1452
Brugia malayi TAR-binding protein 0.006 0.1 0.1
Entamoeba histolytica cysteine protease, putative 0.0014 0.0043 0.0318
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0025 0.0276 0.0276
Onchocerca volvulus Slit protein homolog 0.0073 0.1285 0.1285
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0027 0.0321 0.2388
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0097 0.1781 0.1781
Brugia malayi AMP-binding enzyme family protein 0.0041 0.0606 0.0606
Echinococcus granulosus FTZ F1 alpha 0.0205 0.4058 0.4058
Entamoeba histolytica cysteine protease, putative 0.0014 0.0043 0.0318
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0013 0.0014 0.0104
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0027 0.0321 0.0321
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Loa Loa (eye worm) RNA binding protein 0.006 0.1 0.1
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Schistosoma mansoni cathepsin s 0.0025 0.0276 0.0276
Schistosoma mansoni phd/f-box containing protein 0.0013 0.0014 0.0014
Schistosoma mansoni tar DNA-binding protein 0.006 0.1 0.1
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0014 0.0043 0.0318
Brugia malayi Steroid receptor seven-up type 2 0.0205 0.4058 0.4058
Echinococcus multilocularis isocitrate dehydrogenase 0.0027 0.0321 0.0321
Mycobacterium ulcerans acyl-CoA synthetase 0.0041 0.0606 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0027 0.0321 0.2388
Plasmodium falciparum serine repeat antigen 3 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0031 0.0389 0.5
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0097 0.1781 0.1781
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0205 0.4058 0.4058
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0354 0.5844
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0027 0.0321 0.0321
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0014 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0051 0.0817 0.0817
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0041 0.0606 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0024 0.0246 0.0246
Schistosoma mansoni hypothetical protein 0.0322 0.6506 0.6506
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0014 0.0043 0.0318
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0205 0.4058 0.4058
Loa Loa (eye worm) hypothetical protein 0.0205 0.4058 0.4058
Brugia malayi hypothetical protein 0.0024 0.0246 0.0246
Brugia malayi nuclear receptor NHR-67 0.0097 0.1781 0.1781
Brugia malayi jmjC domain containing protein 0.0013 0.0014 0.0014
Echinococcus granulosus cpg binding protein 0.0024 0.025 0.025
Leishmania major hypothetical protein, conserved 0.0013 0.0014 0.0104
Brugia malayi Calcium binding EGF domain containing protein 0.0073 0.1285 0.1285
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0014 0.0043 0.0043
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0205 0.4058 0.4058
Brugia malayi nuclear receptor RXR 0.0097 0.1781 0.1781
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Brugia malayi photoreceptor-specific nuclear receptor 0.0205 0.4058 0.4058
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0205 0.4058 0.4058
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.1346 1
Schistosoma mansoni hypothetical protein 0.0091 0.1655 0.1655
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0571 0.4243
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Loa Loa (eye worm) hypothetical protein 0.0041 0.0606 0.0606
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0097 0.1781 0.1781
Brugia malayi AMP-binding enzyme family protein 0.0041 0.0606 0.0606
Echinococcus granulosus notch 0.0073 0.1285 0.1285
Onchocerca volvulus 0.0205 0.4058 0.4058
Brugia malayi Nuclear hormone receptor E75 0.0097 0.1781 0.1781
Brugia malayi cathepsin L precursor 0.0014 0.0043 0.0043
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0014 0.0043 0.0318
Brugia malayi Cathepsin L-like precursor 0.0076 0.1346 0.1346
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0051 0.0817 0.6075
Loa Loa (eye worm) hypothetical protein 0.0108 0.2025 0.2025
Loa Loa (eye worm) cysteine protease 0.0076 0.1346 0.1346
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0012 0.0005 0.0005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0205 0.4058 0.4058
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0.0043 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Echinococcus granulosus cathepsin b 0.0014 0.0043 0.0043
Leishmania major hypothetical protein, conserved 0.0024 0.0246 0.183
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Loa Loa (eye worm) isocitrate dehydrogenase 0.0027 0.0321 0.0321
Brugia malayi Animal haem peroxidase family protein 0.0488 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0271 0.0271
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0571 0.4243
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Echinococcus granulosus cathepsin L cysteine proteinase 0.0076 0.1346 0.1346
Onchocerca volvulus Cathepsin F homolog 0.0076 0.1346 0.1346
Loa Loa (eye worm) fibroinase 0.0076 0.1346 0.1346
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Brugia malayi Nuclear hormone receptor-like 1 0.0205 0.4058 0.4058
Echinococcus multilocularis cysteine protease 0.0076 0.1346 0.1346
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Trypanosoma cruzi cysteine proteinase, putative 0.0039 0.0571 0.4243
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0043 0.0318
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0031 0.0389 0.6421
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0014 0.0043 0.0318
Trypanosoma cruzi cruzipain precursor, putative 0.0076 0.1346 1
Loa Loa (eye worm) Notch2 0.0073 0.1285 0.1285
Echinococcus multilocularis neurogenic locus notch protein 0.0073 0.1285 0.1285
Onchocerca volvulus Cathepsin L homolog 0.0076 0.1346 0.1346
Plasmodium vivax unspecified product 0.0025 0.0276 0.2052
Echinococcus granulosus dnaJ subfamily B 0.0322 0.6506 0.6506
Onchocerca volvulus Neurogenic locus notch protein homolog 0.0073 0.1285 0.1285
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0205 0.4058 0.4058
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0042 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0005
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0027 0.0321 0.0321
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0043 0.0318
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0246 0.183
Schistosoma mansoni Pro-neuregulin-4 membrane-bound isoform (Pro-NRG4) [Contains: Neuregulin-4 (NRG-4)] 0.0073 0.1285 0.1285
Echinococcus multilocularis neurogenic locus protein delta 0.0073 0.1285 0.1285
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0076 0.1346 1
Echinococcus multilocularis protein jagged 1 0.0073 0.1285 0.1285
Schistosoma mansoni notch 0.0073 0.1285 0.1285
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Loa Loa (eye worm) animal heme peroxidase 0.0488 1 1
Loa Loa (eye worm) latrophilin receptor protein 2 0.0042 0.0631 0.0631
Leishmania major cathepsin L-like protease 0.0076 0.1346 1
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0076 0.1346 1
Entamoeba histolytica cysteine proteinase, putative 0.0051 0.0817 0.6075
Loa Loa (eye worm) cathepsin B 0.0014 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0389 0.0389
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0205 0.4058 0.4058
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0133 0.2538 0.2538
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0076 0.1346 0.1346
Trypanosoma cruzi cysteine peptidase, putative 0.0039 0.0571 0.4243
Entamoeba histolytica cysteine protease, putative 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0039 0.0571 0.4243
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0041 0.0606 1
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0013 0.0014 0.0104
Echinococcus multilocularis fat cadherin tumor suppressor 0.0073 0.1285 0.1285
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0205 0.4058 0.4058
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0205 0.4058 0.4058
Brugia malayi orphan nuclear receptor NR2E1 0.0097 0.1781 0.1781
Schistosoma mansoni phosphatidylserine receptor 0.0013 0.0014 0.0014
Plasmodium falciparum serine repeat antigen 4 0.0014 0.0043 0.0318
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0097 0.1781 0.1781
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0076 0.1346 0.1346
Brugia malayi jmjC domain containing protein 0.0047 0.0745 0.0745
Onchocerca volvulus Dual oxidase homolog 0.0488 1 1
Echinococcus granulosus cathepsin b 0.0014 0.0043 0.0043
Schistosoma mansoni steroid hormone receptor ad4bp 0.0205 0.4058 0.4058
Schistosoma mansoni hypothetical protein 0.0042 0.0631 0.0631
Brugia malayi EGF-like domain containing protein 0.0073 0.1285 0.1285
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0014 0.0043 0.0318
Brugia malayi Nuclear hormone receptor-like 1 0.0108 0.2025 0.2025
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0043
Plasmodium falciparum serine repeat antigen 7 0.0014 0.0043 0.0318
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0014 0.0043 0.0318
Brugia malayi Latrophilin receptor protein 2 0.0042 0.0631 0.0631
Echinococcus multilocularis neurogenic locus protein delta 0.0073 0.1285 0.1285
Loa Loa (eye worm) jmjC domain-containing protein 0.0049 0.0773 0.0773
Leishmania major cysteine peptidase A (CPA) 0.0076 0.1346 1
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0205 0.4058 0.4058
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0027 0.0321 0.0321
Echinococcus multilocularis phd:f box containing protein 0.0013 0.0014 0.0014
Schistosoma mansoni hypothetical protein 0.0293 0.5897 0.5897
Brugia malayi hypothetical protein 0.0391 0.7966 0.7966
Echinococcus multilocularis cathepsin L 0.0039 0.0571 0.0571
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0205 0.4058 0.4058
Schistosoma mansoni notch 0.0073 0.1285 0.1285
Onchocerca volvulus 0.0076 0.1346 0.1346
Leishmania major cathepsin L-like protease 0.0076 0.1346 1
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Brugia malayi nuclear hormone receptor 0.0097 0.1781 0.1781
Loa Loa (eye worm) hypothetical protein 0.0076 0.1346 0.1346
Entamoeba histolytica cysteine proteinase, putative 0.0076 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Onchocerca volvulus 0.0391 0.7966 0.7966
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Onchocerca volvulus Putative cubilin 0.0073 0.1285 0.1285
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0076 0.1346 0.1346
Schistosoma mansoni hypothetical protein 0.0073 0.1285 0.1285
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0108 0.2025 0.2025
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0042 0.0631 0.0631
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0034 0.0034
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Schistosoma mansoni hypothetical protein 0.0073 0.1285 0.1285
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0048 0.0754 0.0754
Echinococcus granulosus slit 2 protein 0.0073 0.1285 0.1285
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0014 0.0043 0.0318
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Schistosoma mansoni slit 0.0073 0.1285 0.1285
Brugia malayi EGF-like domain containing protein 0.0073 0.1285 0.1285
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0039 0.0571 0.4243
Brugia malayi Calcium binding EGF domain containing protein 0.0073 0.1285 0.1285
Schistosoma mansoni thyroid hormone receptor 0.0205 0.4058 0.4058
Onchocerca volvulus Neurogenic locus notch homolog 0.0073 0.1285 0.1285
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0.0043 0.0318
Onchocerca volvulus Huntingtin homolog 0.0326 0.6605 0.6605
Loa Loa (eye worm) hypothetical protein 0.0147 0.2843 0.2843
Trypanosoma cruzi cysteine peptidase, putative 0.0025 0.0276 0.2052
Brugia malayi Cadherin domain containing protein 0.0073 0.1285 0.1285
Entamoeba histolytica cysteine proteinase 1, putative 0.0039 0.0571 0.4243
Echinococcus multilocularis GPCR, family 2 0.0042 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0205 0.4058 0.4058
Echinococcus granulosus neurogenic locus notch protein 0.0073 0.1285 0.1285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0051 0.0817 0.0817
Plasmodium vivax unspecified product 0.0014 0.0043 0.0318
Loa Loa (eye worm) ctsf protein 0.0076 0.1346 0.1346
Brugia malayi tailless protein 0.0097 0.1781 0.1781
Onchocerca volvulus Chorion peroxidase homolog 0.0488 1 1
Brugia malayi hypothetical protein 0.0108 0.2025 0.2025
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Echinococcus granulosus tar DNA binding protein 0.006 0.1 0.1
Loa Loa (eye worm) animal heme peroxidase 0.0488 1 1
Brugia malayi nuclear receptor NHR-88 0.0097 0.1781 0.1781
Onchocerca volvulus Cathepsin L homolog 0.0014 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0073 0.1285 0.1285
Brugia malayi nuclear receptor RXR 0.0108 0.2025 0.2025
Loa Loa (eye worm) animal heme peroxidase 0.0488 1 1
Toxoplasma gondii isocitrate dehydrogenase 0.0027 0.0321 0.2388
Echinococcus multilocularis cpg binding protein 0.0024 0.025 0.025
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0205 0.4058 0.4058
Echinococcus multilocularis neurogenic locus notch protein 4 0.0073 0.1285 0.1285
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0097 0.1781 0.1781
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Onchocerca volvulus Peroxidasin homolog 0.0488 1 1
Schistosoma mansoni notch 0.0073 0.1285 0.1285
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0108 0.2025 0.2025
Plasmodium vivax ataxin-2 like protein, putative 0.0024 0.0246 0.183
Loa Loa (eye worm) hypothetical protein 0.0013 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0014 0.0043 0.0318
Toxoplasma gondii isocitrate dehydrogenase 0.0027 0.0321 0.2388
Loa Loa (eye worm) hypothetical protein 0.0108 0.2025 0.2025
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0097 0.1781 0.1781
Schistosoma mansoni nuclear receptor nhr-48 0.0097 0.1781 0.1781
Plasmodium vivax serine-repeat antigen (SERA) 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Schistosoma mansoni hypothetical protein 0.0293 0.5897 0.5897
Brugia malayi jmjC domain containing protein 0.0049 0.0773 0.0773
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0043 0.0318
Brugia malayi Blistered cuticle protein 3 0.0488 1 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0205 0.4058 0.4058
Plasmodium falciparum ataxin-2 like protein, putative 0.0024 0.0246 0.183
Schistosoma mansoni thyroid hormone receptor 0.0205 0.4058 0.4058
Brugia malayi fibroinase precursor 0.0014 0.0043 0.0043
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0025 0.0276 0.0276
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0014 0.0043 0.0318
Entamoeba histolytica cysteine protease, putative 0.0014 0.0043 0.0318
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Onchocerca volvulus 0.0076 0.1346 0.1346
Schistosoma mansoni jumonji/arid domain-containing protein 0.0049 0.0773 0.0773
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0014 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0025 0.0276 0.0276
Echinococcus multilocularis dnaJ subfamily B 0.0322 0.6506 0.6506
Loa Loa (eye worm) blistered cuticle protein 3 0.0488 1 1
Brugia malayi hypothetical protein 0.0097 0.1781 0.1781
Plasmodium vivax unspecified product 0.0039 0.0571 0.4243
Mycobacterium ulcerans acyl-CoA synthetase 0.0041 0.0606 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0205 0.4058 0.4058
Schistosoma mansoni peroxidasin 0.0488 1 1
Onchocerca volvulus 0.0025 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Loa Loa (eye worm) hypothetical protein 0.0205 0.4058 0.4058
Brugia malayi cathepsin Z-like cysteine proteinase 0.0014 0.0043 0.0043
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.1346 1
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0354 0.5844
Echinococcus multilocularis lysine specific demethylase 6a 0.0013 0.0014 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0205 0.4058 0.4058
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0042 0.0631 0.0631
Plasmodium falciparum serine repeat antigen 8 0.0014 0.0043 0.0318
Echinococcus multilocularis musashi 0.0025 0.0281 0.0281
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Plasmodium falciparum cysteine proteinase falcipain 3 0.0076 0.1346 1
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0025 0.0281 0.0281
Brugia malayi cathepsin B-like cysteine proteinase 0.0014 0.0043 0.0043
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0027 0.0321 0.2388
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0205 0.4058 0.4058
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Plasmodium falciparum serine repeat antigen 6 0.0014 0.0043 0.0318
Echinococcus granulosus phd:f box containing protein 0.0013 0.0014 0.0014
Brugia malayi Cathepsin L-like precursor 0.0025 0.0276 0.0276
Entamoeba histolytica hypothetical protein 0.0014 0.0043 0.0318
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0081 0.1452 0.1452
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0041 0.0606 1
Trypanosoma cruzi major cysteine proteinase, putative 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0091 0.1655 0.1655
Onchocerca volvulus 0.0076 0.1346 0.1346
Loa Loa (eye worm) hypothetical protein 0.0051 0.0817 0.0817
Onchocerca volvulus Huntingtin homolog 0.0326 0.6605 0.6605
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Echinococcus granulosus JmjC domain containing protein 4 0.0013 0.0014 0.0014
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0027 0.0321 0.0321
Trypanosoma brucei PAB1-binding protein , putative 0.0024 0.0246 0.183
Echinococcus multilocularis cathepsin L cysteine protease 0.0076 0.1346 0.1346
Echinococcus granulosus Nuclear hormone receptor HR96 0.0097 0.1781 0.1781
Entamoeba histolytica cysteine proteinase 2 0.0039 0.0571 0.4243
Echinococcus multilocularis lamin dm0 0.0025 0.0281 0.0281
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0081 0.1452 0.1452
Brugia malayi Cathepsin L-like precursor 0.0076 0.1346 0.1346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Trypanosoma cruzi cysteine proteinase, putative 0.0039 0.0571 0.4243
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0081 0.1452 0.1452
Onchocerca volvulus 0.0076 0.1346 0.1346
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Entamoeba histolytica cysteine proteinase, putative 0.0076 0.1346 1
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Brugia malayi jmjC domain containing protein 0.0013 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0014 0.0043 0.0318
Echinococcus multilocularis tar DNA binding protein 0.006 0.1 0.1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Trypanosoma cruzi cysteine protease, putative 0.0039 0.0571 0.4243
Loa Loa (eye worm) hypothetical protein 0.0108 0.2025 0.2025
Brugia malayi RNA recognition motif domain containing protein 0.006 0.1 0.1
Toxoplasma gondii histone lysine methyltransferase SET1 0.0043 0.0647 0.4808
Echinococcus granulosus neurogenic locus notch protein 4 0.0073 0.1285 0.1285
Leishmania major cathepsin L-like protease 0.0076 0.1346 1
Loa Loa (eye worm) animal heme peroxidase 0.0488 1 1
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Schistosoma mansoni protein phosphatase 2C 0.0013 0.0014 0.0014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Echinococcus granulosus protein jagged 2 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Echinococcus granulosus lamin 0.0025 0.0281 0.0281
Echinococcus multilocularis JmjC domain containing protein 4 0.0013 0.0014 0.0014
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Schistosoma mansoni transcription factor LCR-F1 0.007 0.1215 0.1215
Trypanosoma cruzi major cysteine proteinase, putative 0.0014 0.0043 0.0318
Brugia malayi EGF-like domain containing protein 0.0073 0.1285 0.1285
Plasmodium vivax vivapain-2 0.0076 0.1346 1
Brugia malayi ecdysteroid receptor 0.0205 0.4058 0.4058
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0041 0.0606 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0041 0.0606 0.4506
Loa Loa (eye worm) hypothetical protein 0.0031 0.0389 0.0389
Schistosoma mansoni hypothetical protein 0.0073 0.1285 0.1285
Echinococcus granulosus cysteine protease 0.0039 0.0571 0.0571
Echinococcus granulosus protein jagged 2 0.0073 0.1285 0.1285
Schistosoma mansoni jumonji/arid domain-containing protein 0.0049 0.0773 0.0773
Brugia malayi cathepsin F-like cysteine proteinase 0.0014 0.0043 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0076 0.1346 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0031 0.0389 0.2893
Entamoeba histolytica acyl-CoA synthetase, putative 0.0041 0.0606 0.4506
Echinococcus granulosus lysine specific demethylase 6a 0.0013 0.0014 0.0014
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0047 0.0745 0.0745
Loa Loa (eye worm) hypothetical protein 0.0147 0.2843 0.2843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0043 0.0318
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0097 0.1781 0.1781
Echinococcus multilocularis protein jagged 2 0.0073 0.1285 0.1285
Brugia malayi jmjC domain containing protein 0.0013 0.0014 0.0014
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0041 0.0606 1
Echinococcus multilocularis cathepsin L 0.0014 0.0043 0.0043
Plasmodium vivax serine-repeat antigen (SERA) 0.0014 0.0043 0.0318
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0041 0.0606 1
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0014 0.0043 0.0318
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0108 0.2025 0.2025
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Schistosoma mansoni hypothetical protein 0.0073 0.1285 0.1285
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0571 0.0571
Loa Loa (eye worm) hypothetical protein 0.0391 0.7966 0.7966
Onchocerca volvulus 0.0041 0.0606 0.0606
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Toxoplasma gondii preprocathepsin c precursor, putative 0.0014 0.0043 0.0318
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0097 0.1781 0.1781
Brugia malayi hypothetical protein 0.0097 0.1781 0.1781
Plasmodium vivax vivapain-1 0.0039 0.0571 0.4243
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0205 0.4058 0.4058
Echinococcus multilocularis muscleblind protein 0.0147 0.2843 0.2843
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0034 0.0034
Schistosoma mansoni nuclear hormone receptor 0.0205 0.4058 0.4058
Brugia malayi cathepsin L-like cysteine proteinase 0.0014 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0043 0.0318
Trypanosoma cruzi PAB1-binding protein , putative 0.0024 0.0246 0.183
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0205 0.4058 0.4058
Loa Loa (eye worm) hypothetical protein 0.0205 0.4058 0.4058
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0039 0.0571 0.4243
Brugia malayi Animal haem peroxidase family protein 0.0488 1 1
Loa Loa (eye worm) hypothetical protein 0.0205 0.4058 0.4058
Echinococcus multilocularis nuclear receptor nhr 48 0.0097 0.1781 0.1781
Brugia malayi steroid hormone receptor 0.0205 0.4058 0.4058
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0043
Echinococcus multilocularis slit 2 protein 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0097 0.1781 0.1781
Brugia malayi nuclear hormone receptor family member nhr-6 0.0097 0.1781 0.1781
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0205 0.4058 0.4058
Brugia malayi Papain family cysteine protease containing protein 0.0076 0.1346 0.1346
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0029 0.0354 0.5844
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0205 0.4058 0.4058
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0014 0.0043 0.0318
Brugia malayi GCC2 and GCC3 family protein 0.0073 0.1285 0.1285
Schistosoma mansoni lamin 0.0025 0.0281 0.0281
Schistosoma mansoni RAR-like nuclear receptor 0.0205 0.4058 0.4058
Schistosoma mansoni nuclear hormone receptor 0.0097 0.1781 0.1781
Echinococcus multilocularis peroxidasin 0.0488 1 1
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0013 0.0014 0.0014
Entamoeba histolytica cysteine proteinase, putative 0.0039 0.0571 0.4243
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0014 0.0043 0.0043
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0013 0.0014 0.0014
Loa Loa (eye worm) TAR-binding protein 0.006 0.1 0.1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Brugia malayi Papain family cysteine protease containing protein 0.0039 0.0571 0.0571
Brugia malayi Muscle positioning protein 4 0.0073 0.1285 0.1285
Schistosoma mansoni cathepsin C 0.0014 0.0043 0.0043
Schistosoma mansoni tar DNA-binding protein 0.006 0.1 0.1
Loa Loa (eye worm) hypothetical protein 0.0042 0.0631 0.0631
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0014 0.0043 0.0318
Plasmodium falciparum serine repeat antigen 2 0.0014 0.0043 0.0318
Brugia malayi Cathepsin L-like precursor 0.0076 0.1346 0.1346
Loa Loa (eye worm) hypothetical protein 0.0205 0.4058 0.4058
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0013 0.0014 0.0104
Brugia malayi intermediate filament protein 0.0025 0.0281 0.0281
Echinococcus granulosus cathepsin L 0.0014 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0014 0.0043 0.0318
Onchocerca volvulus 0.0488 1 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0041 0.0606 0.4506
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0043 0.0318
Echinococcus granulosus fibropellin Ia 0.0073 0.1285 0.1285
Mycobacterium ulcerans acyl-CoA synthetase 0.0041 0.0606 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0389 0.0389
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0014 0.0043 0.0043
Schistosoma mansoni peroxidasin 0.0488 1 1
Brugia malayi CXXC zinc finger family protein 0.0023 0.0222 0.0222
Brugia malayi Papain family cysteine protease containing protein 0.0014 0.0043 0.0043
Onchocerca volvulus 0.0097 0.1781 0.1781
Echinococcus granulosus delta-like protein 1 0.0073 0.1285 0.1285
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0326 0.6605 0.6605
Echinococcus granulosus jumonji domain containing 1A 0.0013 0.0014 0.0014
Plasmodium falciparum cysteine proteinase falcipain 1 0.0039 0.0571 0.4243
Brugia malayi Cathepsin L-like precursor 0.0076 0.1346 0.1346
Brugia malayi Cathepsin L-like precursor 0.0076 0.1346 0.1346
Brugia malayi nuclear receptor NHR-88 0.0205 0.4058 0.4058
Entamoeba histolytica cysteine protease, putative 0.0014 0.0043 0.0318
Loa Loa (eye worm) hypothetical protein 0.0205 0.4058 0.4058
Trypanosoma cruzi cysteine peptidase, putative 0.0076 0.1346 1
Echinococcus multilocularis FTZ F1 alpha 0.0205 0.4058 0.4058
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0014 0.0043 0.0318
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.007 0.1215 0.1215
Brugia malayi Muscleblind-like protein 0.0147 0.2843 0.2843
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0039 0.0571 0.4243
Echinococcus granulosus neural cadherin 0.0073 0.1285 0.1285
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0027 0.0321 0.2388
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Schistosoma mansoni hypothetical protein 0.0042 0.0631 0.0631
Onchocerca volvulus 0.0488 1 1
Brugia malayi isocitrate dehydrogenase 0.0027 0.0321 0.0321
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0014 0.0043 0.0043
Giardia lamblia High cysteine protein 0.0073 0.1285 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0205 0.4058 0.4058
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0027 0.0321 0.2388
Echinococcus granulosus lysine specific demethylase 5A 0.0049 0.0773 0.0773
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0571 0.0571
Brugia malayi notch-like transmembrane receptor 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0326 0.6605 0.6605
Entamoeba histolytica cysteine protease, putative 0.0076 0.1346 1
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0108 0.2025 0.2025
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0205 0.4058 0.4058
Echinococcus granulosus GPCR family 2 0.0042 0.0631 0.0631
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0013 0.0014 0.0104
Toxoplasma gondii cathepsin CPC1 0.0014 0.0043 0.0318
Echinococcus granulosus muscleblind protein 0.0147 0.2843 0.2843
Plasmodium falciparum acyl-CoA synthetase 0.0031 0.0389 0.2893
Echinococcus granulosus Nuclear hormone receptor HR96 0.0097 0.1781 0.1781
Loa Loa (eye worm) hypothetical protein 0.0073 0.1285 0.1285
Echinococcus multilocularis cathepsin L cysteine protease 0.0076 0.1346 0.1346
Loa Loa (eye worm) hypothetical protein 0.0133 0.2538 0.2538
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Brugia malayi Nuclear hormone receptor E75 0.0097 0.1781 0.1781
Entamoeba histolytica hypothetical protein 0.007 0.1215 0.9033
Echinococcus granulosus cathepsin l1 0.0051 0.0817 0.0817
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0076 0.1346 1
Echinococcus granulosus geminin 0.0293 0.5897 0.5897
Onchocerca volvulus 0.0076 0.1346 0.1346
Loa Loa (eye worm) hypothetical protein 0.0014 0.0043 0.0043
Brugia malayi Cathepsin L-like precursor 0.0051 0.0817 0.0817
Brugia malayi Cathepsin L-like precursor 0.0051 0.0817 0.0817
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Brugia malayi AMP-binding enzyme family protein 0.0041 0.0606 0.0606
Schistosoma mansoni hypothetical protein 0.007 0.1215 0.1215
Schistosoma mansoni nuclear receptor 0.0097 0.1781 0.1781
Onchocerca volvulus 0.0488 1 1
Schistosoma mansoni zinc finger protein 0.0097 0.1781 0.1781
Onchocerca volvulus 0.0051 0.0817 0.0817
Loa Loa (eye worm) nuclear receptor NHR-67 0.0097 0.1781 0.1781
Brugia malayi EGF-like domain containing protein 0.0073 0.1285 0.1285
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0081 0.1452 0.1452
Toxoplasma gondii cathepsin CPL 0.0076 0.1346 1
Entamoeba histolytica cysteine protease, putative 0.0039 0.0571 0.4243
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0108 0.2025 0.2025
Echinococcus granulosus cathepsin l1 0.0076 0.1346 0.1346
Echinococcus granulosus protein jagged 1 0.0073 0.1285 0.1285
Loa Loa (eye worm) hypothetical protein 0.0488 1 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0042 0.0631 0.0631
Loa Loa (eye worm) hypothetical protein 0.0025 0.0276 0.0276
Leishmania major cathepsin L-like protease 0.0076 0.1346 1
Onchocerca volvulus Cathepsin L homolog 0.0076 0.1346 0.1346
Loa Loa (eye worm) hypothetical protein 0.0031 0.0389 0.0389
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0014 0.0043 0.0318
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0076 0.1346 1
Brugia malayi cathepsin F-like cysteine proteinase 0.0025 0.0276 0.0276
Echinococcus granulosus neurogenic locus notch protein 0.0073 0.1285 0.1285
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0205 0.4058 0.4058
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0076 0.1346 1
Schistosoma mansoni retinoic acid receptor RXR 0.0205 0.4058 0.4058
Brugia malayi EGF-like domain containing protein 0.0073 0.1285 0.1285
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0039 0.0571 0.0571

Activities

Activity type Activity value Assay description Source Reference
Activity (functional) = 20.15 % Antioxidant activity assessed as nitric oxide radical scavenging activity at 5 ug/ml after 150 mins ChEMBL. 17336429
Activity (functional) = 22 % Analgesic activity in Albino mouse assessed as protection against acetic acid-induced writhing at 10 mg/kg, ip within 30 mins ChEMBL. 17336429
Activity (functional) = 22 % Analgesic activity in Albino mouse assessed as protection against acetic acid-induced writhing at 10 mg/kg, ip within 30 mins ChEMBL. 17336429
Activity (functional) = 23.47 % Antioxidant activity assessed as nitric oxide radical scavenging activity at 10 ug/ml after 150 mins ChEMBL. 17336429
Activity (functional) = 30.63 % Antioxidant activity assessed as nitric oxide radical scavenging activity at 15 ug/ml after 150 mins ChEMBL. 17336429
Activity (functional) = 32.47 % Antioxidant activity assessed as nitric oxide radical scavenging activity at 20 ug/ml after 150 mins ChEMBL. 17336429
Activity (functional) = 38.47 % Antioxidant activity assessed as nitric oxide radical scavenging activity at 25 ug/ml after 150 mins ChEMBL. 17336429
Activity (functional) = 41.23 % Antioxidant activity assessed as nitric oxide radical scavenging activity at 30 ug/ml after 150 mins ChEMBL. 17336429
Activity (functional) = 50.98 % Antioxidant activity assessed as nitric oxide radical scavenging activity at 35 ug/ml after 150 mins ChEMBL. 17336429
Activity (functional) = 69 % Antiinflammatory activity in Albino rat assessed as protection against carrageenin-induced hind paw oedema at 40 mg/kg, po after 3 hrs ChEMBL. 17336429
Activity (functional) = 72 % Antiinflammatory activity in Albino rat assessed as protection against carrageenin-induced hind paw oedema at 10 mg/kg, po after 3 hrs ChEMBL. 17336429
Activity (functional) = 75 % Antiinflammatory activity in Albino rat assessed as protection against carrageenin-induced hind paw oedema at 20 mg/kg, po after 3 hrs ChEMBL. 17336429
IC50 (functional) = 36.57 ug ml-1 Inhibition of nitric oxide radical scavenging activity ChEMBL. 17336429

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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