Detailed information for compound 47089

Basic information

Technical information
  • TDR Targets ID: 47089
  • Name: 1-Deoxy-1-Methoxycarbamido-Beta-D-Gluco-2-Hep tulopyranosonamide
  • MW: 280.232 | Formula: C9H16N2O8
  • H donors: 6 H acceptors: 6 LogP: -2.9 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: OCC1OC(NC(=O)OC)(C(=O)N)C(C(C1O)O)O
  • InChi: 1S/C9H16N2O8/c1-18-8(17)11-9(7(10)16)6(15)5(14)4(13)3(2-12)19-9/h3-6,12-15H,2H2,1H3,(H2,10,16)(H,11,17)
  • InChiKey: ZQTAMPRAONLFQI-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • methyl N-[(2S,3R,4S,5S,6R)-2-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbamate
  • methyl N-[2-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbamate
  • methyl N-[2-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]carbamate
  • N-[2-carbamoyl-3,4,5-trihydroxy-6-(hydroxymethyl)-2-tetrahydropyranyl]carbamic acid methyl ester
  • methyl N-[2-aminocarbonyl-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]carbamate
  • N-(2-carbamoyl-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl)carbamic acid methyl ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Cation transporter family protein 0.0074 0.0618 0.0941
Schistosoma mansoni growth hormone secretagogue receptor 0.016 0.1561 0.4801
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.006 0.006
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.016 0.1561 0.4801
Echinococcus granulosus nicotinic acetylcholine receptor a11 subunit 0.0074 0.0618 0.0837
Echinococcus granulosus 7TM GPCR rhodopsin 0.016 0.1561 0.2112
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0074 0.0618 0.0941
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0143 0.2964
Echinococcus granulosus G protein coupled receptor 139 0.016 0.1561 0.2112
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0031 0.0161 0.0245
Trichomonas vaginalis glycogen phosphorylase, putative 0.0261 0.2651 0.9481
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1018 0.3697
Brugia malayi neuropeptide F receptor 0.016 0.1561 0.2375
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0276 0.0373
Echinococcus granulosus alpha 1A adrenergic receptor 0.016 0.1561 0.2112
Schistosoma mansoni hypothetical protein 0.016 0.1561 0.4801
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0054 0.0402 0.0612
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0194 0.0598
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0054 0.0402 0.1236
Brugia malayi 6-phosphofructokinase 0.011 0.1018 0.155
Entamoeba histolytica hypothetical protein 0.0044 0.0301 0.0929
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0301 0.0458
Schistosoma mansoni flap endonuclease-1 0.0024 0.0079 0.0243
Onchocerca volvulus 0.016 0.1561 0.2376
Echinococcus granulosus acetylcholine receptor subunit beta 1 0.0074 0.0618 0.0837
Brugia malayi hypothetical protein 0.0022 0.006 0.0092
Brugia malayi excitatory GABA receptor EXP-1A 0.0074 0.0618 0.0941
Brugia malayi Intermediate filament tail domain containing protein 0.0031 0.0161 0.0245
Echinococcus granulosus neuropeptide s receptor 0.0697 0.7388 1
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.1018 0.3126
Onchocerca volvulus 0.0035 0.0194 0.0296
Brugia malayi regulator of G-protein signaling egl-10 0.0022 0.006 0.0092
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0044 0.0301 0.0458
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Schistosoma mansoni peptide (allatostatin)-like receptor 0.016 0.1561 0.4801
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0316 0.325 1
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Brugia malayi carbohydrate phosphorylase 0.0261 0.2651 0.4035
Leishmania major pyruvate kinase 0.0039 0.0238 0.166
Echinococcus multilocularis nicotinic acetylcholine receptor subunit alpha 8 0.0074 0.0618 0.0618
Schistosoma mansoni nAChR subunit (ShAR1-alpha-like) 0.0074 0.0618 0.1902
Echinococcus multilocularis rhodopsin orphan GPCR 0.016 0.1561 0.1561
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0074 0.0618 0.0618
Echinococcus granulosus glycine receptor subunit alpha 1 0.0074 0.0618 0.0837
Brugia malayi Neuronal acetylcholine receptor protein, alpha-2 chain precursor 0.0029 0.0137 0.0208
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) nicotinic acetylcholine receptor non-alpha subunit 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.006 0.0185
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0238 0.0363
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0143 0.2964
Toxoplasma gondii LsmAD domain-containing protein 0.0026 0.0097 0.1715
Schistosoma mansoni myosin xvIII 0.016 0.1561 0.4801
Schistosoma mansoni nAChR subunit 0.0074 0.0618 0.1902
Echinococcus multilocularis g protein coupled receptor 0.016 0.1561 0.1561
Trypanosoma brucei PAB1-binding protein , putative 0.0026 0.0097 0.0154
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0276 0.0848
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.006 0.0092
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.016 0.1561 0.4801
Echinococcus multilocularis fmrfamide receptor 0.016 0.1561 0.1561
Schistosoma mansoni regulator of G protein signaling 0.0022 0.006 0.0185
Schistosoma mansoni regulator of G protein signaling 0.0022 0.006 0.0185
Echinococcus multilocularis lamin 0.0031 0.0161 0.0161
Echinococcus granulosus tm gpcr rhodopsin 0.016 0.1561 0.2112
Brugia malayi hypothetical protein 0.0054 0.0402 0.0612
Mycobacterium leprae Probable lipase LipE 0.0042 0.0276 0.0478
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0074 0.0618 0.1902
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0074 0.0618 0.0618
Echinococcus multilocularis sodium:chloride dependent neurotransmitter 0.0054 0.0402 0.0402
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0622 0.1913
Loa Loa (eye worm) CYP4Cod1 0.0024 0.0083 0.0126
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) ACC-1 protein 0.0074 0.0618 0.0941
Brugia malayi follicle stimulating hormone receptor 0.0426 0.4448 0.677
Loa Loa (eye worm) RGS-3 protein 0.0022 0.006 0.0092
Brugia malayi cytoplasmic intermediate filament protein 0.0017 0.0002 0.0004
Echinococcus granulosus g-protein coupled receptor 0.016 0.1561 0.2112
Schistosoma mansoni biogenic amine receptor 0.016 0.1561 0.4801
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.006 0.0185
Echinococcus multilocularis g-protein coupled receptor 0.016 0.1561 0.1561
Echinococcus multilocularis geminin 0.0196 0.1947 0.1947
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0054 0.0402 0.0612
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Brugia malayi glutamate-gated chloride channel alpha3A subunit, putative 0.0029 0.0137 0.0208
Mycobacterium ulcerans glycogen phosphorylase GlgP 0.0113 0.1044 1
Echinococcus multilocularis musashi 0.0031 0.0161 0.0161
Toxoplasma gondii hypothetical protein 0.0054 0.0402 1
Brugia malayi 6-phosphofructokinase 0.011 0.1018 0.155
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0194 0.0263
Echinococcus granulosus sex peptide receptor 0.016 0.1561 0.2112
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.006 0.0081
Echinococcus multilocularis allatostatin A receptor 0.016 0.1561 0.1561
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.0092
Loa Loa (eye worm) hypothetical protein 0.0042 0.0276 0.0419
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.016 0.1561 0.2375
Brugia malayi acetylcholine receptor, alpha-type subunit unc-38 precursor 0.0074 0.0618 0.0941
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.006 0.0081
Entamoeba histolytica glycogen phosphorylase, putative 0.0113 0.1044 0.3796
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0054 0.0402 0.1236
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.006 0.0185
Onchocerca volvulus 0.016 0.1561 0.2376
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0276 0.0149
Loa Loa (eye worm) hypothetical protein 0.0273 0.2788 0.4243
Loa Loa (eye worm) serotonin transporter b 0.0316 0.325 0.4946
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.0092
Loa Loa (eye worm) TYRA-2 protein 0.016 0.1561 0.2375
Schistosoma mansoni amine GPCR 0.016 0.1561 0.4801
Echinococcus granulosus neuropeptide receptor 0.016 0.1561 0.2112
Brugia malayi Acetylcholine receptor protein, alpha-like chain 1 precursor 0.0029 0.0137 0.0208
Brugia malayi nicotinic acetylcholine receptor alpha subunit, putative 0.0074 0.0618 0.0941
Echinococcus multilocularis serotonin transporter 0.0316 0.325 0.325
Brugia malayi TAR-binding protein 0.0074 0.0622 0.0946
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0276 0.0149
Echinococcus granulosus nischarin 0.0636 0.6732 0.9112
Onchocerca volvulus 0.0042 0.0276 0.0419
Loa Loa (eye worm) acetylcholine receptor protein 0.0029 0.0137 0.0208
Schistosoma mansoni 6-phosphofructokinase 0.011 0.1018 0.3133
Schistosoma mansoni acetylcholine receptor-related 0.0029 0.0137 0.042
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.016 0.1561 0.4801
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0143 0.2964
Echinococcus multilocularis survival motor neuron protein 1 0.0273 0.2788 0.2788
Schistosoma mansoni biogenic amine (dopamine) receptor 0.016 0.1561 0.4801
Brugia malayi Cation transporter family protein 0.0074 0.0618 0.0941
Brugia malayi phosphofructokinase 0.011 0.1018 0.155
Echinococcus granulosus serotonin transporter 0.0316 0.325 0.4399
Brugia malayi PXA domain containing protein 0.0037 0.0223 0.0339
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0097 0.1715
Echinococcus granulosus hypothetical protein 0.016 0.1561 0.2112
Onchocerca volvulus Glycogen phosphorylase homolog 0.0261 0.2651 0.4036
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.016 0.1561 0.2375
Schistosoma mansoni adenoreceptor 0.016 0.1561 0.4801
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0194 0.435
Plasmodium vivax hypothetical protein, conserved 0.0054 0.0402 1
Brugia malayi ORL1-like opioid receptor 0.016 0.1561 0.2375
Onchocerca volvulus 0.0074 0.0618 0.0941
Loa Loa (eye worm) acetylcholine receptor alpha subunit 0.0074 0.0618 0.0941
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0216 0.0216
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0054 0.0402 0.0612
Schistosoma mansoni sodium-dependent amino acid transporter 0.0054 0.0402 0.1236
Onchocerca volvulus 0.0074 0.0618 0.0941
Echinococcus multilocularis tar DNA binding protein 0.0074 0.0622 0.0622
Echinococcus multilocularis tachykinin peptides receptor 99D 0.016 0.1561 0.1561
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0097 0.0154
Echinococcus multilocularis neuropeptides capa receptor 0.016 0.1561 0.1561
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0029 0.0137 0.0208
Echinococcus granulosus biogenic amine 5HT receptor 0.0284 0.2904 0.393
Schistosoma mansoni serine/threonine protein kinase 0.0022 0.006 0.0185
Schistosoma mansoni axis inhibition protein axin 0.0022 0.006 0.0185
Chlamydia trachomatis glycogen phosphorylase 0.0261 0.2651 1
Onchocerca volvulus 0.016 0.1561 0.2376
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0056 0.0425 0.0647
Echinococcus multilocularis nAChR subunit 0.0074 0.0618 0.0618
Brugia malayi Pre-SET motif family protein 0.0035 0.0194 0.0296
Loa Loa (eye worm) hypothetical protein 0.0054 0.0402 0.0612
Echinococcus granulosus somatostatin receptor 0.016 0.1561 0.2112
Schistosoma mansoni sodium/chloride dependent transporter 0.0316 0.325 1
Schistosoma mansoni hypothetical protein 0.016 0.1561 0.4801
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Loa Loa (eye worm) ACC-1 protein 0.0074 0.0618 0.0941
Echinococcus multilocularis serotonin receptor 0.0284 0.2904 0.2904
Brugia malayi Dopamine receptor 0.016 0.1561 0.2375
Echinococcus multilocularis pyruvate kinase 0.003 0.015 0.015
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.0092
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.016 0.1561 0.1561
Echinococcus multilocularis g protein coupled receptor 0.016 0.1561 0.1561
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Onchocerca volvulus Putative nachr subunit 0.0074 0.0618 0.0941
Schistosoma mansoni neuropeptide F-like receptor 0.016 0.1561 0.4801
Onchocerca volvulus 0.0031 0.0161 0.0245
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0107 0.0253
Echinococcus multilocularis somatostatin receptor 0.016 0.1561 0.1561
Onchocerca volvulus 0.016 0.1561 0.2376
Echinococcus granulosus regulator of G protein signaling 7 0.0022 0.006 0.0081
Echinococcus granulosus tachykinin peptides receptor 99D 0.016 0.1561 0.2112
Schistosoma mansoni nAChR subunit (ShAR1-beta2-like) 0.0074 0.0618 0.1902
Loa Loa (eye worm) hypothetical protein 0.0316 0.325 0.4946
Echinococcus granulosus neuropeptides capa receptor 0.016 0.1561 0.2112
Echinococcus granulosus rhodopsin orphan GPCR 0.016 0.1561 0.2112
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0022 0.006 0.0092
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Echinococcus multilocularis biogenic amine (5HT) receptor 0.016 0.1561 0.1561
Onchocerca volvulus 0.0042 0.0276 0.0419
Onchocerca volvulus 0.0042 0.0276 0.0419
Loa Loa (eye worm) hypothetical protein 0.0031 0.0155 0.0236
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0107 0.1966
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0143 0.0304
Schistosoma mansoni neuropeptide receptor 0.016 0.1561 0.4801
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0074 0.0618 0.0941
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0276 0.0788
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0276 0.0149
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1018 0.3505
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0276 0.0788
Loa Loa (eye worm) glycogen phosphorylase 0.0261 0.2651 0.4035
Schistosoma mansoni neuropeptide f receptor 76f 0.016 0.1561 0.4801
Echinococcus granulosus nAChR subunit 0.0074 0.0618 0.0837
Echinococcus granulosus nicotinic acetylcholine receptor subunit type 0.0074 0.0618 0.0837
Loa Loa (eye worm) hypothetical protein 0.0054 0.0402 0.0612
Loa Loa (eye worm) hypothetical protein 0.0026 0.0097 0.0148
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0316 0.325 0.4946
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Entamoeba histolytica hypothetical protein 0.0037 0.0216 0.0602
Brugia malayi Dopamine receptor protein 1 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.2432 0.3702
Echinococcus granulosus axis inhibition protein axin 0.0022 0.006 0.0081
Loa Loa (eye worm) hypothetical protein 0.0039 0.0238 0.0363
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0044 0.0301 0.0458
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0107 0.0276
Loa Loa (eye worm) hypothetical protein 0.0035 0.0194 0.0296
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Echinococcus granulosus orexin receptor type 2 0.016 0.1561 0.2112
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Schistosoma mansoni hypothetical protein 0.016 0.1561 0.4801
Brugia malayi hypothetical protein 0.0124 0.1162 0.1768
Brugia malayi Serotonin/octopamine receptor family protein 7 0.016 0.1561 0.2375
Brugia malayi Pre-SET motif family protein 0.0241 0.2432 0.3702
Mycobacterium tuberculosis Conserved protein 0.0042 0.0276 0.0149
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0276 0.2003
Brugia malayi acetylcholine receptor alpha subunit precursor, putative 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Brugia malayi beta-lactamase family protein 0.0042 0.0276 0.0419
Echinococcus multilocularis expressed protein 0.0431 0.4506 0.4506
Echinococcus multilocularis sodium and chloride dependent glycine 0.0054 0.0402 0.0402
Echinococcus multilocularis dro:myosuppressin receptor 0.016 0.1561 0.1561
Onchocerca volvulus 0.0044 0.0301 0.0458
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0022 0.006 0.0092
Loa Loa (eye worm) TAR-binding protein 0.0074 0.0622 0.0946
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Schistosoma mansoni hypothetical protein 0.0196 0.1947 0.599
Loa Loa (eye worm) GABA receptor subunit 0.0044 0.0301 0.0458
Loa Loa (eye worm) solute carrier family 6 member 4 0.0316 0.325 0.4946
Brugia malayi Regulator of G protein signaling domain containing protein 0.0022 0.006 0.0092
Schistosoma mansoni alpha-1 adrenergic receptor 0.016 0.1561 0.4801
Brugia malayi RE15519p 0.016 0.1561 0.2375
Trichomonas vaginalis set domain proteins, putative 0.0274 0.2793 1
Schistosoma mansoni nAChR subunit 0.0074 0.0618 0.1902
Onchocerca volvulus Nischarin homolog 0.0621 0.6569 1
Loa Loa (eye worm) glutamate-gated chloride channel alpha3A subunit 0.0074 0.0618 0.0941
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0044 0.0301 0.0926
Echinococcus granulosus neuropeptide Y receptor 0.016 0.1561 0.2112
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Echinococcus granulosus geminin 0.0196 0.1947 0.2635
Echinococcus granulosus rhodopsin orphan GPCR 0.016 0.1561 0.2112
Giardia lamblia Glycogen phosphorylase 0.0261 0.2651 1
Echinococcus granulosus nicotinic acetylcholine receptor beta 1 subunit 0.0074 0.0618 0.0837
Schistosoma mansoni histamine h1 receptor 0.016 0.1561 0.4801
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0054 0.0402 1
Echinococcus granulosus tm gpcr rhodopsin 0.016 0.1561 0.2112
Schistosoma mansoni regulator of G protein signaling 0.0022 0.006 0.0185
Echinococcus granulosus glycogen phosphorylase 0.0261 0.2651 0.3589
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Echinococcus multilocularis beta adrenergic receptor kinase 0.0022 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0426 0.4448 0.677
Loa Loa (eye worm) intermediate filament protein 0.0031 0.0161 0.0245
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.016 0.1561 0.2112
Echinococcus multilocularis lamin dm0 0.0031 0.0161 0.0161
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.1018 0.2816
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.016 0.1561 0.4801
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Brugia malayi Melatonin receptor type 1A 0.016 0.1561 0.2375
Brugia malayi hypothetical protein 0.0029 0.0137 0.0208
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.016 0.1561 0.1561
Echinococcus multilocularis regulator of G protein signaling 0.0022 0.006 0.006
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.016 0.1561 0.1561
Loa Loa (eye worm) pyruvate kinase-PB 0.0027 0.0112 0.017
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Schistosoma mansoni survival motor neuron protein 0.0056 0.0425 0.1308
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0074 0.0618 0.1902
Brugia malayi hypothetical protein 0.0029 0.0137 0.0208
Echinococcus granulosus neuropeptides capa receptor 0.016 0.1561 0.2112
Brugia malayi hypothetical protein 0.0037 0.0216 0.0329
Brugia malayi hypothetical protein 0.0022 0.006 0.0092
Schistosoma mansoni nAChR subunit (ShAR1-beta-like) 0.0074 0.0618 0.1902
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0054 0.0402 0.1236
Echinococcus granulosus thyrotropin releasing hormone receptor 0.016 0.1561 0.2112
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0226 0.0344
Schistosoma mansoni glycogen phosphorylase 0.0261 0.2651 0.8158
Schistosoma mansoni nAChR subunit 0.0074 0.0618 0.1902
Mycobacterium ulcerans hypothetical protein 0.0042 0.0276 0.2003
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0276 0.0419
Schistosoma mansoni hypothetical protein 0.016 0.1561 0.4801
Onchocerca volvulus 0.0074 0.0618 0.0941
Schistosoma mansoni glycogen phosphorylase 0.0113 0.1044 0.3212
Echinococcus granulosus neuropeptide FF receptor 2 0.016 0.1561 0.2112
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0143 0.2964
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.016 0.1561 0.1561
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0017 0.0002 0.0004
Loa Loa (eye worm) hypothetical protein 0.0054 0.0402 0.0612
Echinococcus multilocularis pyruvate kinase 0.0039 0.0238 0.0238
Schistosoma mansoni biogenic amine (dopamine) receptor 0.016 0.1561 0.4801
Echinococcus granulosus 7tm_1 domain containing protein 0.016 0.1561 0.2112
Leishmania major pyruvate kinase 0.0039 0.0238 0.166
Echinococcus multilocularis pyruvate kinase 0.002 0.0034 0.0034
Schistosoma mansoni Cys-loop ligand gated ion channel subunit 0.0074 0.0618 0.1902
Brugia malayi PXA domain containing protein 0.0037 0.0223 0.0339
Plasmodium vivax SET domain protein, putative 0.0035 0.0194 0.435
Echinococcus granulosus axis inhibition protein axin 0.0022 0.006 0.0081
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0054 0.0402 0.1236
Brugia malayi Protein kinase domain containing protein 0.0017 0.000000026163 0.000000039816
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0276 0.2058
Echinococcus multilocularis nicotinic acetylcholine receptor alpha subunit 0.0074 0.0618 0.0618
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0083 0.0126
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.016 0.1561 0.2375
Schistosoma mansoni sodium/chloride dependent transporter 0.0054 0.0402 0.1236
Brugia malayi Neurotransmitter-gated ion-channel transmembrane region family protein 0.0074 0.0618 0.0941
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0022 0.006 0.006
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Schistosoma mansoni amine GPCR 0.016 0.1561 0.4801
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.0238 0.0652
Echinococcus multilocularis uncharacterized sodium dependent transporter 0.0054 0.0402 0.0402
Echinococcus granulosus nicotinic acetylcholine receptor subunit alpha 8 0.0074 0.0618 0.0837
Loa Loa (eye worm) hypothetical protein 0.0017 0.0002 0.0002
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.016 0.1561 0.1561
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1018 0.3505
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0054 0.0402 1
Echinococcus multilocularis pyruvate kinase 0.002 0.0034 0.0034
Loa Loa (eye worm) hypothetical protein 0.0054 0.0402 0.0612
Plasmodium falciparum pyruvate kinase 0.0039 0.0238 0.5548
Onchocerca volvulus 0.0029 0.0137 0.0208
Echinococcus multilocularis glycogen phosphorylase 0.0261 0.2651 0.2651
Echinococcus multilocularis sex peptide receptor 0.016 0.1561 0.1561
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0054 0.0402 0.1236
Echinococcus multilocularis glycogen phosphorylase 0.0261 0.2651 0.2651
Schistosoma mansoni neuropeptide F-like receptor 0.016 0.1561 0.4801
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0107 0.0107
Echinococcus granulosus g protein coupled receptor 0.016 0.1561 0.2112
Schistosoma mansoni nAChR subunit 0.0074 0.0618 0.1902
Schistosoma mansoni nicotinic acetylcholine receptor alpha 0.0044 0.0301 0.0926
Onchocerca volvulus Neuropeptide F receptor homolog 0.016 0.1561 0.2376
Loa Loa (eye worm) Sodium:neurotransmitter symporter family protein 0.0054 0.0402 0.0612
Echinococcus granulosus g protein coupled receptor 0.016 0.1561 0.2112
Echinococcus multilocularis serotonin receptor 0.0284 0.2904 0.2904
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Onchocerca volvulus 0.016 0.1561 0.2376
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0054 0.0402 0.0612
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0143 0.0304
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.016 0.1561 0.1561
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0074 0.0622 0.0946
Brugia malayi AKH receptor 0.016 0.1561 0.2375
Echinococcus multilocularis neuropeptide FF receptor 2 0.016 0.1561 0.1561
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0022 0.006 0.0092
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0622 0.1913
Schistosoma mansoni biogenic amine (5HT) receptor 0.016 0.1561 0.4801
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0276 0.0788
Schistosoma mansoni opsin-like receptor 0.016 0.1561 0.4801
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.016 0.1561 0.1561
Onchocerca volvulus 0.0029 0.0137 0.0208
Echinococcus granulosus rhodopsin orphan GPCR 0.016 0.1561 0.2112
Brugia malayi G protein-coupled receptor F59B2.13 0.016 0.1561 0.2375
Echinococcus granulosus flap endonuclease 1 0.0026 0.0107 0.0144
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0137 0.042
Trypanosoma brucei pyruvate kinase 1, putative 0.0039 0.0238 0.166
Echinococcus multilocularis Glycosyl transferase, family 35 0.0261 0.2651 0.2651
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0268 0.2733 1
Brugia malayi beta-lactamase family protein 0.0042 0.0276 0.0419
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.016 0.1561 0.2112
Loa Loa (eye worm) cytochrome P450 family protein 0.0024 0.0083 0.0126
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.016 0.1561 0.1561
Onchocerca volvulus 0.0031 0.0161 0.0245
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0029 0.0137 0.0137
Schistosoma mansoni opsin-like receptor 0.016 0.1561 0.4801
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0022 0.006 0.0185
Mycobacterium tuberculosis Conserved protein 0.0042 0.0276 0.0149
Schistosoma mansoni z-protein (S1r protein) 0.0022 0.006 0.0185
Loa Loa (eye worm) hypothetical protein 0.0027 0.0112 0.017
Onchocerca volvulus 0.016 0.1561 0.2376
Brugia malayi intermediate filament protein 0.0031 0.0161 0.0245
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.0092
Schistosoma mansoni glycogen phosphorylase 0.0261 0.2651 0.8158
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0622 0.1913
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.016 0.1561 0.2375
Onchocerca volvulus 0.0054 0.0402 0.0612
Brugia malayi Cytochrome P450 family protein 0.0024 0.0083 0.0126
Brugia malayi putative neuropeptide receptor NPR1 0.016 0.1561 0.2375
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0137 0.0208
Entamoeba histolytica glycogen phosphorylase, putative 0.0113 0.1044 0.3796
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.016 0.1561 0.4801
Echinococcus granulosus rhodopsin orphan GPCR 0.016 0.1561 0.2112
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.0092
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0143 0.2964
Brugia malayi Flap endonuclease-1 0.0026 0.0107 0.0162
Echinococcus granulosus nicotinic acetylcholine receptor alpha subunit 0.0074 0.0618 0.0837
Onchocerca volvulus 0.0056 0.0425 0.0647
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Echinococcus multilocularis nAChR subunit 0.0044 0.0301 0.0301
Chlamydia trachomatis pyruvate kinase 0.0039 0.0238 0.0379
Onchocerca volvulus 0.0274 0.2795 0.4255
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0622 0.1913
Echinococcus multilocularis Regulator of G protein signaling 20 0.0022 0.006 0.006
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0216 0.0293
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0107 0.0253
Schistosoma mansoni neurotransmitter gated ion channel 0.0029 0.0137 0.042
Loa Loa (eye worm) hypothetical protein 0.0042 0.0276 0.0419
Trypanosoma brucei pyruvate kinase 1 0.0039 0.0238 0.166
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Schistosoma mansoni 6-phosphofructokinase 0.011 0.1018 0.3133
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0074 0.0618 0.0941
Echinococcus granulosus pyruvate kinase 0.002 0.0034 0.0047
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.018 0.0244
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0276 0.0149
Echinococcus granulosus nuclear factor of activated T cells 5 0.0085 0.0744 0.1007
Onchocerca volvulus 0.016 0.1561 0.2376
Brugia malayi sulfakinin receptor protein 0.016 0.1561 0.2375
Echinococcus multilocularis neuropeptide receptor 0.016 0.1561 0.1561
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Echinococcus multilocularis rhodopsin orphan GPCR 0.016 0.1561 0.1561
Echinococcus granulosus expressed protein 0.0431 0.4506 0.6099
Echinococcus multilocularis orexin receptor type 2 0.016 0.1561 0.1561
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0194 0.0598
Loa Loa (eye worm) hypothetical protein 0.0042 0.0276 0.0419
Entamoeba histolytica glycogen phosphorylase, putative 0.0261 0.2651 1
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0107 0.017
Echinococcus multilocularis acetylcholine receptor subunit beta 1 0.0074 0.0618 0.0618
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.006 0.006
Brugia malayi Uncoordinated protein 44 0.0017 0.000000026163 0.000000039816
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1018 0.3697
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0316 0.325 0.4946
Onchocerca volvulus 0.016 0.1561 0.2376
Brugia malayi RNA binding protein 0.0074 0.0622 0.0946
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0107 0.1966
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0074 0.0618 0.0941
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0276 0.2003
Echinococcus multilocularis alpha 1A adrenergic receptor 0.016 0.1561 0.1561
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1018 0.3505
Echinococcus multilocularis neuronal acetylcholine receptor subunit alpha 4 0.0074 0.0618 0.0618
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0074 0.0618 0.0941
Brugia malayi Cation transporter family protein 0.0074 0.0618 0.0941
Mycobacterium tuberculosis Conserved protein 0.0042 0.0276 0.0149
Mycobacterium ulcerans pyruvate kinase 0.0039 0.0238 0.1616
Loa Loa (eye worm) neuropeptide F receptor 0.016 0.1561 0.2375
Echinococcus multilocularis gamma aminobutyric acid receptor subunit 0.0029 0.0137 0.0137
Echinococcus granulosus Ankyrin 0.0017 0.0002 0.0002
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0276 0.0788
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1018 0.3697
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.016 0.1561 0.2112
Echinococcus multilocularis neuropeptides capa receptor 0.016 0.1561 0.1561
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0276 0.0276
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Mycobacterium ulcerans beta-lactamase 0.0042 0.0276 0.2003
Echinococcus granulosus fmrfamide receptor 0.016 0.1561 0.2112
Toxoplasma gondii Sodium:neurotransmitter symporter family protein 0.0054 0.0402 1
Brugia malayi Cytochrome P450 family protein 0.0024 0.0083 0.0126
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Brugia malayi gamma-aminobutyric-acid receptor beta subunit precursor 0.0074 0.0618 0.0941
Echinococcus multilocularis G-protein coupled receptor, putative 0.016 0.1561 0.1561
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.016 0.1561 0.2112
Brugia malayi nicotinic acetylcholine receptor beta-1 chain precursor 0.0074 0.0618 0.0941
Onchocerca volvulus 0.0054 0.0402 0.0612
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.1018 0.1018
Onchocerca volvulus 0.0054 0.0402 0.0612
Plasmodium falciparum flap endonuclease 1 0.0026 0.0107 0.1966
Echinococcus multilocularis G protein coupled receptor 139 0.016 0.1561 0.1561
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Echinococcus granulosus sodium and chloride dependent glycine 0.0054 0.0402 0.0544
Chlamydia trachomatis Ssodium-dependent amino acid transporter 0.0054 0.0402 0.1031
Loa Loa (eye worm) hypothetical protein 0.0042 0.0276 0.0419
Loa Loa (eye worm) hypothetical protein 0.0054 0.0402 0.0612
Entamoeba histolytica glycogen phosphorylase, putative 0.0261 0.2651 1
Loa Loa (eye worm) neuropeptide F receptor 0.016 0.1561 0.2375
Schistosoma mansoni neuropeptide receptor 0.016 0.1561 0.4801
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.1018 1
Schistosoma mansoni sodium/chloride dependent neurotransmitter transporter 0.0054 0.0402 0.1236
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.006 0.006
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0022 0.006 0.0081
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.016 0.1561 0.2112
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0143 0.0304
Schistosoma mansoni biogenic amine (dopamine) receptor 0.016 0.1561 0.4801
Schistosoma mansoni amine GPCR 0.016 0.1561 0.4801
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Schistosoma mansoni nAChR subunit 0.0029 0.0137 0.042
Plasmodium vivax amine transporter, putative 0.0054 0.0402 1
Toxoplasma gondii hypothetical protein 0.0054 0.0402 1
Onchocerca volvulus 0.0074 0.0618 0.0941
Onchocerca volvulus 0.016 0.1561 0.2376
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.0238 0.166
Trichomonas vaginalis pyruvate kinase, putative 0.0039 0.0238 0.0652
Plasmodium vivax ataxin-2 like protein, putative 0.0026 0.0097 0.1715
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Echinococcus multilocularis Cys loop ligand gated ion channel subunit 0.0074 0.0618 0.0618
Schistosoma mansoni axis inhibition protein axin 0.0022 0.006 0.0185
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0017 0.000000026163 0.000000035414
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0143 0.0416
Brugia malayi acetylcholine receptor protein, alpha-like chain, putative 0.0074 0.0618 0.0941
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0194 0.0194
Echinococcus granulosus neuronal acetylcholine receptor subunit alpha 4 0.0074 0.0618 0.0837
Echinococcus multilocularis regulator of G protein signaling 3 0.0022 0.006 0.006
Brugia malayi larval opioid receptor 0.016 0.1561 0.2375
Echinococcus multilocularis neuropeptide Y receptor 0.016 0.1561 0.1561
Echinococcus granulosus rhodopsin orphan GPCR 0.016 0.1561 0.2112
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0216 0.0665
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0276 0.0149
Loa Loa (eye worm) PXA domain-containing protein 0.0037 0.0223 0.0339
Echinococcus multilocularis neuropeptide receptor A26 0.0697 0.7388 0.7388
Schistosoma mansoni nAChR subunit 0.0074 0.0618 0.1902
Echinococcus multilocularis pyruvate kinase 0.002 0.0034 0.0034
Echinococcus multilocularis regulator of G protein signaling 7 0.0022 0.006 0.006
Brugia malayi hypothetical protein 0.0026 0.0097 0.0148
Echinococcus granulosus glycine receptor subunit alpha 1 0.0074 0.0618 0.0837
Leishmania major hypothetical protein, conserved 0.0042 0.0276 0.2058
Onchocerca volvulus 0.016 0.1561 0.2376
Treponema pallidum sodium- and chloride- dependent transporter 0.0316 0.325 1
Schistosoma mansoni opsin-like receptor 0.016 0.1561 0.4801
Echinococcus granulosus Glycosyl transferase family 35 0.0261 0.2651 0.3589
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0143 0.0304
Echinococcus multilocularis Ankyrin 0.0017 0.0002 0.0002
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0017 0.0002 0.0005
Schistosoma mansoni amine GPCR 0.016 0.1561 0.4801
Echinococcus granulosus glycine receptor subunit beta 0.0074 0.0618 0.0837
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0143 0.0304
Schistosoma mansoni pyruvate kinase 0.0039 0.0238 0.0733
Loa Loa (eye worm) hypothetical protein 0.0316 0.325 0.4946
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0276 0.2058
Entamoeba histolytica glycogenphosphorylase, putative 0.0113 0.1044 0.3796
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0238 0.0363
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0276 0.2058
Echinococcus granulosus allatostatin A receptor 0.016 0.1561 0.2112
Schistosoma mansoni regulator of G protein signaling 0.0022 0.006 0.0185
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.016 0.1561 0.1561
Brugia malayi Pyruvate kinase, muscle isozyme 0.0039 0.0238 0.0363
Schistosoma mansoni lamin 0.0031 0.0161 0.0496
Brugia malayi Dopamine receptor protein 2 0.016 0.1561 0.2375
Toxoplasma gondii pyruvate kinase PyK1 0.0039 0.0238 0.5548
Echinococcus granulosus regulator of G protein signaling 3 0.0022 0.006 0.0081
Loa Loa (eye worm) phosphofructokinase 0.011 0.1018 0.155
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0054 0.0402 0.1236
Mycobacterium ulcerans lipase LipD 0.0042 0.0276 0.2003
Leishmania major hypothetical protein, conserved 0.0026 0.0097 0.0154
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Onchocerca volvulus 0.0029 0.0137 0.0208
Echinococcus granulosus tm gpcr rhodopsin 0.016 0.1561 0.2112
Onchocerca volvulus 0.016 0.1561 0.2376
Brugia malayi hypothetical protein 0.0029 0.0137 0.0208
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0276 0.6562
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0238 0.0363
Echinococcus multilocularis pyruvate kinase 0.0039 0.0238 0.0238
Mycobacterium tuberculosis Probable glycogen phosphorylase GlgP 0.0113 0.1044 0.3229
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0029 0.0137 0.0185
Echinococcus multilocularis sodium and chloride dependent glycine 0.0054 0.0402 0.0402
Loa Loa (eye worm) hypothetical protein 0.0054 0.0402 0.0612
Brugia malayi GnHR receptor homolog 0.016 0.1561 0.2375
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.1018 1
Echinococcus multilocularis axis inhibition protein axin 0.0022 0.006 0.006
Brugia malayi Pyruvate kinase, M2 isozyme 0.0039 0.0238 0.0363
Plasmodium vivax pyruvate kinase, putative 0.0039 0.0238 0.5548
Loa Loa (eye worm) excitatory GABA receptor EXP-1A 0.0074 0.0618 0.0941
Schistosoma mansoni pyruvate kinase 0.0039 0.0238 0.0733
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Brugia malayi gonadotropin-releasing hormone receptor 2 0.016 0.1561 0.2375
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0054 0.0402 0.0544
Schistosoma mansoni lamin 0.0031 0.0161 0.0496
Brugia malayi A-kinase anchor protein 10, precursor 0.0022 0.006 0.0092
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Schistosoma mansoni neuropeptide receptor 0.016 0.1561 0.4801
Loa Loa (eye worm) hypothetical protein 0.0042 0.0276 0.0419
Echinococcus granulosus tar DNA binding protein 0.0074 0.0622 0.0842
Echinococcus granulosus rhodopsin orphan GPCR 0.016 0.1561 0.2112
Echinococcus granulosus beta-adrenergic receptor kinase 0.0022 0.006 0.0081
Echinococcus granulosus uncharacterized sodium dependent transporter 0.0054 0.0402 0.0544
Echinococcus granulosus sodium:chloride dependent neurotransmitter 0.0054 0.0402 0.0544
Onchocerca volvulus 0.0074 0.0618 0.0941
Loa Loa (eye worm) ligand-Gated ion Channel family member 0.0074 0.0618 0.0941
Echinococcus granulosus g protein coupled receptor 0.016 0.1561 0.2112
Onchocerca volvulus 0.016 0.1561 0.2376
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Brugia malayi Tachykinin-like peptides receptor 99D 0.016 0.1561 0.2375
Brugia malayi Sodium:neurotransmitter symporter family protein 1, putative 0.0054 0.0402 0.0612
Brugia malayi Cytochrome P450 family protein 0.0037 0.0226 0.0344
Echinococcus granulosus pyruvate kinase 0.002 0.0034 0.0047
Onchocerca volvulus 0.016 0.1561 0.2376
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Echinococcus multilocularis glycine receptor subunit beta 0.0074 0.0618 0.0618
Brugia malayi hypothetical protein 0.0029 0.0137 0.0208
Echinococcus multilocularis glycine receptor subunit alpha 1 0.0074 0.0618 0.0618
Schistosoma mansoni hypothetical protein 0.0056 0.0425 0.1308
Echinococcus granulosus glycogen phosphorylase 0.0261 0.2651 0.3589
Echinococcus multilocularis nicotinic acetylcholine receptor subunit type 0.0029 0.0137 0.0137
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0107 0.018
Echinococcus multilocularis glycine receptor subunit beta 0.0074 0.0618 0.0618
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0276 0.0848
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0194 0.0598
Loa Loa (eye worm) hypothetical protein 0.0284 0.2904 0.4419
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.1018 0.155
Trichomonas vaginalis esterase, putative 0.0042 0.0276 0.0788
Echinococcus granulosus glycine receptor subunit alpha 1 0.0074 0.0618 0.0837
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0194 0.0194
Entamoeba histolytica hypothetical protein 0.0037 0.0216 0.0602
Echinococcus multilocularis rhodopsin orphan GPCR 0.016 0.1561 0.1561
Echinococcus multilocularis nicotinic acetylcholine receptor a11 subunit 0.0074 0.0618 0.0618
Entamoeba histolytica hypothetical protein 0.0037 0.0216 0.0602
Echinococcus granulosus 6 phosphofructokinase 0.011 0.1018 0.1378
Loa Loa (eye worm) hypothetical protein 0.0031 0.0161 0.0245
Echinococcus multilocularis nischarin 0.0636 0.6732 0.6732
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Brugia malayi putative neuropeptide receptor 0.016 0.1561 0.2375
Schistosoma mansoni amine GPCR 0.016 0.1561 0.4801
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.016 0.1561 0.1561
Leishmania major ATP-dependent phosphofructokinase 0.011 0.1018 1
Schistosoma mansoni intermediate filament proteins 0.0031 0.0161 0.0496
Entamoeba histolytica hypothetical protein 0.0037 0.0216 0.0602
Brugia malayi Death domain containing protein 0.0017 0.000000026163 0.000000039816
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0143 0.0304
Echinococcus multilocularis rhodopsin orphan GPCR 0.016 0.1561 0.1561
Loa Loa (eye worm) LGC-31 protein 0.0074 0.0618 0.0941
Schistosoma mansoni hypothetical protein 0.0196 0.1947 0.599
Echinococcus granulosus Regulator of G protein signaling 20 0.0022 0.006 0.0081
Echinococcus multilocularis rhodopsin orphan GPCR 0.016 0.1561 0.1561
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.016 0.1561 0.1561
Brugia malayi hypothetical protein 0.0622 0.6571 1
Loa Loa (eye worm) hypothetical protein 0.0622 0.6571 1
Schistosoma mansoni tar DNA-binding protein 0.0074 0.0622 0.1913
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0276 0.0419
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0022 0.006 0.0092
Plasmodium falciparum ataxin-2 like protein, putative 0.0026 0.0097 0.1715
Echinococcus granulosus lamin dm0 0.0031 0.0161 0.0218
Trypanosoma cruzi pyruvate kinase 2, putative 0.0039 0.0238 0.166
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1018 0.3505
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Loa Loa (eye worm) pyruvate kinase 0.0039 0.0238 0.0363
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Schistosoma mansoni hypothetical protein 0.0037 0.0216 0.0665
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Echinococcus granulosus neuropeptide Y receptor 0.016 0.1561 0.2112
Echinococcus granulosus rhodopsin orphan GPCR 0.016 0.1561 0.2112
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.1018 1
Echinococcus granulosus serotonin receptor 0.016 0.1561 0.2112
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Entamoeba histolytica pyruvate kinase, putative 0.0027 0.0112 0.0198
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Schistosoma mansoni nAChR subunit 0.0029 0.0137 0.042
Echinococcus granulosus sodium and chloride dependent glycine 0.0054 0.0402 0.0544
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0137 0.0208
Onchocerca volvulus 0.016 0.1561 0.2376
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0276 0.0149
Echinococcus multilocularis neuropeptide receptor 0.016 0.1561 0.1561
Schistosoma mansoni sodium-dependent neurotransmitter transporter 0.0054 0.0402 0.1236
Brugia malayi hypothetical protein 0.0273 0.2788 0.4243
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0107 0.0162
Schistosoma mansoni neuropeptide receptor 0.016 0.1561 0.4801
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Onchocerca volvulus 0.016 0.1561 0.2376
Echinococcus granulosus Cys loop ligand gated ion channel subunit 0.0074 0.0618 0.0837
Loa Loa (eye worm) hypothetical protein 0.0042 0.0276 0.0419
Loa Loa (eye worm) hypothetical protein 0.0022 0.006 0.0092
Plasmodium falciparum transporter, putative 0.0054 0.0402 1
Schistosoma mansoni ankyrin 23/unc44 0.0017 0.000000026163 0.000000080495
Brugia malayi Serotonin receptor 0.016 0.1561 0.2375
Echinococcus granulosus dro:myosuppressin receptor 0.016 0.1561 0.2112
Brugia malayi regulator of G-protein signaling rgs-7 0.0022 0.006 0.0092
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0054 0.0402 0.0612
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Onchocerca volvulus 0.0316 0.325 0.4948
Brugia malayi beta-lactamase 0.0042 0.0276 0.0419
Echinococcus granulosus biogenic amine 5HT receptor 0.016 0.1561 0.2112
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0074 0.0618 0.0941
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.016 0.1561 0.4801
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Onchocerca volvulus 0.016 0.1561 0.2376
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.016 0.1561 0.4801
Schistosoma mansoni nAChR subunit 0.0074 0.0618 0.1902
Echinococcus multilocularis fmrfamide receptor 0.016 0.1561 0.1561
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Echinococcus granulosus nAChR subunit 0.0044 0.0301 0.0407
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Echinococcus granulosus pyruvate kinase 0.0039 0.0238 0.0323
Echinococcus multilocularis rhodopsin orphan GPCR 0.016 0.1561 0.1561
Schistosoma mansoni neurotransmitter gated ion channel 0.0044 0.0301 0.0926
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0143 0.0321
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0238 0.0363
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Echinococcus granulosus lamin 0.0031 0.0161 0.0218
Echinococcus granulosus gamma aminobutyric acid receptor subunit 0.0029 0.0137 0.0185
Loa Loa (eye worm) norepinephrine transporter 0.0316 0.325 0.4946
Echinococcus granulosus pyruvate kinase 0.002 0.0034 0.0047
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0284 0.2904 0.4419
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0085 0.0744 0.0744
Echinococcus granulosus sodium dependent neurotransmitter transporter 0.0054 0.0402 0.0544
Echinococcus granulosus intermediate filament protein 0.0031 0.0161 0.0218
Brugia malayi G-protein coupled receptor 0.016 0.1561 0.2375
Toxoplasma gondii ABC1 family protein 0.0042 0.0276 0.6562
Brugia malayi Neurotransmitter-gated ion-channel ligand binding domain containing protein 0.0029 0.0137 0.0208
Echinococcus granulosus peptide allatostatin:somatostatin 0.016 0.1561 0.2112
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0143 0.2964
Brugia malayi RNA recognition motif domain containing protein 0.0074 0.0622 0.0946
Echinococcus granulosus neuropeptide receptor A26 0.0697 0.7388 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.016 0.1561 0.2375
Giardia lamblia Pyruvate kinase 0.0039 0.0238 0.0779
Echinococcus multilocularis neuropeptide s receptor 0.0697 0.7388 0.7388
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.1018 0.9733
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Onchocerca volvulus Pyruvate kinase homolog 0.0039 0.0238 0.0363
Onchocerca volvulus 0.0044 0.0301 0.0458
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.1018 0.155
Brugia malayi Serotonin receptor 0.016 0.1561 0.2375
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0107 0.0253
Loa Loa (eye worm) G-protein coupled receptor 0.016 0.1561 0.2375
Schistosoma mansoni sodium/chloride dependent transporter 0.0054 0.0402 0.1236
Loa Loa (eye worm) RNA binding protein 0.0074 0.0622 0.0946
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0143 0.0304
Loa Loa (eye worm) melatonin receptor type 1A 0.016 0.1561 0.2375
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0143 0.2964
Onchocerca volvulus 0.016 0.1561 0.2376
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.016 0.1561 0.2376
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.016 0.1561 0.4801
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0276 0.0788
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Echinococcus multilocularis rhodopsin orphan GPCR 0.016 0.1561 0.1561
Loa Loa (eye worm) hypothetical protein 0.0322 0.3318 0.505
Schistosoma mansoni biogenic amine (5HT) receptor 0.0284 0.2904 0.8933
Echinococcus multilocularis sodium dependent neurotransmitter transporter 0.0054 0.0402 0.0402
Echinococcus granulosus pyruvate kinase 0.0039 0.0238 0.0323
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Schistosoma mansoni nAChR subunit 0.0074 0.0618 0.1902
Loa Loa (eye worm) hypothetical protein 0.0044 0.0301 0.0458
Loa Loa (eye worm) hypothetical protein 0.0074 0.0618 0.0941
Schistosoma mansoni acetylcholine receptor subunit beta 0.0029 0.0137 0.042
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Echinococcus multilocularis g protein coupled receptor 0.016 0.1561 0.1561
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.016 0.1561 0.4801
Loa Loa (eye worm) neuronal acetylcholine receptor protein 0.0029 0.0137 0.0208
Brugia malayi G-protein coupled receptor 0.016 0.1561 0.2375
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Loa Loa (eye worm) nicotinic acetylcholine receptor alpha subunit 0.0074 0.0618 0.0941
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Schistosoma mansoni regulator of G protein signaling 0.0022 0.006 0.0185
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0276 0.0149
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0276 0.0478
Loa Loa (eye worm) G-protein coupled receptor 0.016 0.1561 0.2375
Echinococcus granulosus glycine receptor subunit beta 0.0074 0.0618 0.0837
Brugia malayi hypothetical protein 0.016 0.1561 0.2375
Brugia malayi neuropeptide F receptor 0.016 0.1561 0.2375
Brugia malayi Hypothetical glycine receptor like protein T20B12.9 in chromosome III 0.0044 0.0301 0.0458
Loa Loa (eye worm) hypothetical protein 0.016 0.1561 0.2375
Echinococcus multilocularis nicotinic acetylcholine receptor beta 1 subunit 0.0074 0.0618 0.0618
Plasmodium falciparum amino acid transporter, putative 0.0054 0.0402 1
Loa Loa (eye worm) beta-lactamase 0.0042 0.0276 0.0419
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0022 0.006 0.0185
Onchocerca volvulus 0.0074 0.0618 0.0941
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0017 0.000000026163 0.000000026163
Echinococcus multilocularis neuropeptide Y receptor 0.016 0.1561 0.1561
Schistosoma mansoni rhodopsin-like orphan GPCR 0.016 0.1561 0.4801
Schistosoma mansoni biogenic amine receptor 0.016 0.1561 0.4801
Echinococcus granulosus neuropeptide receptor 0.016 0.1561 0.2112
Schistosoma mansoni biogenic amine receptor 0.016 0.1561 0.4801
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0194 0.0598
Brugia malayi hypothetical protein 0.0029 0.0137 0.0208
Trichomonas vaginalis glycogen phosphorylase, putative 0.0261 0.2651 0.9481
Trypanosoma cruzi PAB1-binding protein , putative 0.0026 0.0097 0.0154
Brugia malayi G protein-coupled receptor 0.016 0.1561 0.2375
Echinococcus multilocularis rhodopsin orphan GPCR 0.016 0.1561 0.1561
Echinococcus granulosus survival motor neuron protein 1 0.0273 0.2788 0.3774
Loa Loa (eye worm) hypothetical protein 0.0029 0.0137 0.0208
Schistosoma mansoni pyruvate kinase 0.002 0.0034 0.0106

Activities

Activity type Activity value Assay description Source Reference
-Log Ki (binding) = 4.796 Inhibitory activity against glycogen phosphorylase, activity expressed as -logKi ChEMBL. 12502357
Ki (binding) = 0.016 mM Inhibition of rabbit glycogen phosphorylase B enzyme ChEMBL. 9154968
Log K (binding) = 7.881 Binding affinity of the Corticosteroid-Binding Globulin Receptor with cortisol ChEMBL. 10966742
Log Ki (binding) = 3.5 Ability of the compound to inhibit the enzymatic activity (phosphorylase) of rabbit glycogen phosphorylase enzyme. ChEMBL. 9154968
Log Ki (binding) = 4.796 Affinity of the compound was determined on glycogen phosphorylase(GP) enzyme. ChEMBL. 9435905
Log Ki (binding) = 3.5 mM Inhibitory activity against rabbit muscle glycogen phosphorylase ChEMBL. 9406599
Log Ki (binding) = 4.8 mM Inhibitory activity against rabbit muscle glycogen phosphorylase ChEMBL. 9406599
Log Ki (binding) = 4.8 mM Kinetic inhibition constant was evaluated by measuring the inhibition of the glycogen phosphorylase (GP) ChEMBL. 10966742

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

5 literature references were collected for this gene.

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