Detailed information for compound 537733

Basic information

Technical information
  • TDR Targets ID: 537733
  • Name: 3-[4-[[2-(2-chloro-5-nitro-phenyl)-1-(4-metho xyphenyl)-5-oxo-imidazol-4-ylidene]methyl]-N- (2-cyanoethyl)-3-methyl-anilino]propanenitril e
  • MW: 569.01 | Formula: C30H25ClN6O4
  • H donors: 0 H acceptors: 5 LogP: 5.02 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 2
  • SMILES: N#CCCN(c1ccc(c(c1)C)C=C1N=C(N(C1=O)c1ccc(cc1)OC)c1cc(ccc1Cl)[N+](=O)[O-])CCC#N
  • InChi: 1S/C30H25ClN6O4/c1-20-17-23(35(15-3-13-32)16-4-14-33)6-5-21(20)18-28-30(38)36(22-7-10-25(41-2)11-8-22)29(34-28)26-19-24(37(39)40)9-12-27(26)31/h5-12,17-19H,3-4,15-16H2,1-2H3
  • InChiKey: RCIVNQFJYXHCEQ-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 3-[4-[[2-(2-chloro-5-nitrophenyl)-1-(4-methoxyphenyl)-5-oxo-4-imidazolylidene]methyl]-N-(2-cyanoethyl)-3-methylanilino]propanenitrile
  • 3-[[4-[[2-(2-chloro-5-nitro-phenyl)-1-(4-methoxyphenyl)-5-oxo-imidazol-4-ylidene]methyl]-3-methyl-phenyl]-(2-cyanoethyl)amino]propanenitrile
  • 3-[4-[[2-(2-chloro-5-nitro-phenyl)-5-keto-1-(4-methoxyphenyl)-2-imidazolin-4-ylidene]methyl]-N-(2-cyanoethyl)-3-methyl-anilino]propionitrile
  • 3-[4-[[2-(2-chloro-5-nitrophenyl)-1-(4-methoxyphenyl)-5-oxoimidazol-4-ylidene]methyl]-N-(2-cyanoethyl)-3-methylanilino]propanenitrile

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans bacterioferritin BfrA 0.0038 0.0044 0.7378
Onchocerca volvulus Ubiquitin thioesterase ZRANB1 homolog 0.0503 0.107 0.3438
Loa Loa (eye worm) hypothetical protein 0.0042 0.0052 0.0154
Trichomonas vaginalis set domain proteins, putative 0.0274 0.0565 0.1789
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0503 0.107 0.3438
Loa Loa (eye worm) hypothetical protein 0.0134 0.0257 0.0819
Trichomonas vaginalis ion channel nompc, putative 0.0026 0.0017 0.000000010415
Brugia malayi Latrophilin receptor protein 2 0.0071 0.0116 0.0323
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Echinococcus multilocularis tumor protein p63 0.034 0.071 0.0694
Loa Loa (eye worm) hypothetical protein 0.0503 0.107 0.3464
Onchocerca volvulus 0.0503 0.107 0.3438
Schistosoma mansoni DNA ligase IV 0.0033 0.0034 0.0055
Brugia malayi SRC-1 0.0043 0.0055 0.0125
Brugia malayi AMP-binding enzyme family protein 0.0027 0.002 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0048 0.0067 0.0162
Loa Loa (eye worm) hypothetical protein 0.0503 0.107 0.3464
Toxoplasma gondii ABC1 family protein 0.0042 0.0052 0.0116
Brugia malayi TAR-binding protein 0.0145 0.0281 0.0862
Trypanosoma brucei Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Loa Loa (eye worm) RNA binding protein 0.0145 0.0281 0.0898
Echinococcus granulosus tyrosine protein kinase Lyn 0.0043 0.0055 0.0125
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1415 0.3079 1
Trypanosoma brucei unspecified product 0.0037 0.0043 0.0398
Onchocerca volvulus 0.0042 0.0052 0.0116
Trypanosoma cruzi BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0033 0.0034 0.0161
Chlamydia trachomatis DNA topoisomerase I 0.1415 0.3079 1
Mycobacterium ulcerans bacterioferritin BfrB 0.0038 0.0044 0.7378
Onchocerca volvulus Huntingtin homolog 0.0134 0.0257 0.0783
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Echinococcus granulosus tyrosine kinase 0.0037 0.0041 0.0079
Onchocerca volvulus 0.0098 0.0178 0.0525
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0044 0.0255
Mycobacterium ulcerans beta-lactamase 0.0042 0.0052 0.8907
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Plasmodium falciparum RING zinc finger protein, putative 0.0026 0.0017 0.0039
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Brugia malayi Niemann-Pick C1 protein precursor 0.0112 0.0208 0.0622
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0044 0.0088
Loa Loa (eye worm) SRC-1 0.0043 0.0055 0.0164
Giardia lamblia Hypothetical protein 0.0026 0.0017 0.2725
Loa Loa (eye worm) hypothetical protein 0.0134 0.0257 0.0819
Plasmodium vivax RING zinc finger protein, putative 0.0026 0.0017 0.0039
Plasmodium vivax hypothetical protein, conserved 0.1415 0.3079 1
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.1415 0.3079 1
Brugia malayi DKFZp564C0469 protein 0.0033 0.0034 0.0055
Echinococcus granulosus expressed conserved protein 0.0105 0.0193 0.0573
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0055 0.0038
Onchocerca volvulus 0.0503 0.107 0.3438
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0037 0.0041 0.0024
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0336 0.0319
Loa Loa (eye worm) cytochrome P450 family protein 0.0029 0.0024 0.0061
Trichomonas vaginalis ankyrin 2,3/unc44, putative 0.0026 0.0017 0.000000010415
Echinococcus multilocularis replication factor c subunit 1 0.0033 0.0034 0.0017
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0042 0.0052 0.0915
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0241 0.0491 0.1582
Brugia malayi beta-lactamase family protein 0.0042 0.0052 0.0116
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Mycobacterium leprae PROBABLE DNA LIGASE [NAD DEPENDENT] LIGA (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [NAD+]) 0.0033 0.0034 0.4293
Brugia malayi YY1-associated factor 2 0.0503 0.107 0.3438
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0154 0.0301 0.0927
Schistosoma mansoni patched 1 0.0048 0.0067 0.0162
Mycobacterium tuberculosis Conserved protein 0.0042 0.0052 0.0915
Brugia malayi hypothetical protein 0.0134 0.0257 0.0783
Echinococcus multilocularis lysosomal alpha glucosidase 0.017 0.0336 0.0319
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0049
Giardia lamblia Hypothetical protein 0.0026 0.0017 0.2725
Mycobacterium ulcerans esterase/lipase LipP 0.0042 0.0052 0.8907
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0033 0.0034 0.0055
Trypanosoma brucei predicted zinc finger protein 0.0026 0.0017 0.0159
Echinococcus granulosus tyrosine protein kinase ABL1 0.0208 0.0419 0.1313
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0035 0.0037 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.002 0.0088
Mycobacterium ulcerans hypothetical protein 0.0027 0.002 0.2826
Leishmania major hypothetical protein, unknown function 0.0026 0.0017 0.006
Schistosoma mansoni hypothetical protein 0.0071 0.0116 0.0323
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0058 0.0391
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0037 0.0064
Echinococcus multilocularis sterol regulatory element binding protein 0.0048 0.0067 0.005
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0145 0.0281 0.0898
Echinococcus granulosus tyrosine protein kinase Blk 0.0037 0.0041 0.0079
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Plasmodium vivax ataxin-2 like protein, putative 0.0058 0.0088 0.027
Mycobacterium ulcerans hypothetical protein 0.0042 0.0052 0.8907
Schistosoma mansoni hypothetical protein 0.0046 0.0063 0.0149
Echinococcus multilocularis zinc finger protein Ran binding 0.0503 0.107 0.1055
Loa Loa (eye worm) hypothetical protein 0.0042 0.0052 0.0154
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0044 0.0088
Brugia malayi SWIB/MDM2 domain containing protein 0.1415 0.3079 1
Echinococcus granulosus lysosomal alpha glucosidase 0.017 0.0336 0.1041
Echinococcus multilocularis p2X purinoceptor 4 0.0074 0.0124 0.0107
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Leishmania major hypothetical protein, conserved 0.0058 0.0088 0.0731
Echinococcus granulosus tumor protein p63 0.034 0.071 0.2263
Brugia malayi hypothetical protein 0.0037 0.0043 0.0085
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0043 0.0055 0.0038
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0503 0.107 0.3438
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0035 0.0037 0.0064
Loa Loa (eye worm) MH2 domain-containing protein 0.0131 0.0249 0.0794
Echinococcus granulosus sterol regulatory element binding protein 0.0048 0.0067 0.0162
Mycobacterium ulcerans NAD-dependent DNA ligase LigA 0.0033 0.0034 0.5437
Echinococcus granulosus dna polymerase kappa 0.0044 0.0058 0.0135
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0503 0.107 1
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Brugia malayi brahma associated protein 60 kDa 0.1415 0.3079 1
Brugia malayi brahma associated protein 60 kDa 0.1415 0.3079 1
Plasmodium vivax zinc finger protein, putative 0.0026 0.0017 0.0039
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0154 0.0301 0.0927
Echinococcus granulosus survival motor neuron protein 1 0.054 0.1151 0.3704
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0026 0.0018 0.0001
Schistosoma mansoni TRABID protein (C64 family) 0.0503 0.107 0.3438
Echinococcus granulosus nibrin 0.0033 0.0034 0.0055
Loa Loa (eye worm) hypothetical protein 0.0058 0.0088 0.027
Giardia lamblia Zinc finger domain 0.0026 0.0017 0.2725
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0281 0.0862
Loa Loa (eye worm) beta-lactamase 0.0042 0.0052 0.0154
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0027 0.002 0.2826
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0042 0.0052 0.0154
Echinococcus granulosus tyrosine protein kinase Src42A 0.0035 0.0037 0.0066
Echinococcus granulosus Upstream activation factor subunit UAF30 0.1415 0.3079 1
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0094
Loa Loa (eye worm) RiNg Finger protein family member 0.0026 0.0017 0.0039
Echinococcus multilocularis nibrin 0.0033 0.0034 0.0017
Brugia malayi AMP-binding enzyme family protein 0.0027 0.002 0.001
Trichomonas vaginalis ankyrin, putative 0.0026 0.0017 0.000000010415
Leishmania major hypothetical protein, conserved 0.0503 0.107 1
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Mycobacterium leprae conserved hypothetical protein 0.0042 0.0052 1
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0035 0.0037 0.002
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0058 0.0391
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0044 0.1408
Giardia lamblia Ribonuclease 0.0026 0.0017 0.2725
Loa Loa (eye worm) hypothetical protein 0.0223 0.0452 0.1454
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0161
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0058 1
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Echinococcus multilocularis p2X purinoceptor 4 0.0074 0.0124 0.0107
Plasmodium falciparum ataxin-2 like protein, putative 0.0058 0.0088 0.027
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0052 0.0116
Loa Loa (eye worm) hypothetical protein 0.0503 0.107 0.3464
Schistosoma mansoni apoferritin-2 0.0038 0.0044 0.0089
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.002 0.0159
Echinococcus granulosus Niemann Pick C1 protein 0.016 0.0314 0.0968
Trichomonas vaginalis ankyrin, putative 0.0026 0.0017 0.000000010415
Giardia lamblia Ser/Thr protein kinase 0.0026 0.0017 0.2725
Loa Loa (eye worm) hypothetical protein 0.0042 0.0052 0.0154
Brugia malayi hypothetical protein 0.0033 0.0034 0.0055
Trypanosoma brucei mitochondrial RNA binding complex 1 subunit 0.0503 0.107 1
Giardia lamblia Replication factor C, subunit 1 0.0033 0.0034 1
Brugia malayi MH2 domain containing protein 0.0131 0.0249 0.0758
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0048 0.0067 0.02
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0043 0.0055 0.0038
Schistosoma mansoni tyrosine kinase 0.0201 0.0405 0.1266
Trypanosoma cruzi WLM domain containing protein, putative 0.0503 0.107 1
Giardia lamblia Hypothetical protein 0.0026 0.0017 0.2725
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0034 0.0055
Loa Loa (eye worm) TK/ABL protein kinase 0.0208 0.0419 0.1347
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.1415 0.3079 0.3067
Loa Loa (eye worm) hypothetical protein 0.0078 0.0133 0.0416
Loa Loa (eye worm) hypothetical protein 0.0503 0.107 0.3464
Schistosoma mansoni P2X receptor subunit 0.0074 0.0124 0.0349
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.002 0.0005 0.0045
Brugia malayi AMP-binding enzyme family protein 0.0027 0.002 0.001
Entamoeba histolytica hypothetical protein 0.0081 0.0139 0.6418
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Trypanosoma brucei hypothetical protein, conserved 0.0503 0.107 1
Schistosoma mansoni P2X receptor subunit 0.0074 0.0124 0.0349
Toxoplasma gondii ATPase, AAA family protein 0.0033 0.0034 0.0055
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.1415 0.3079 1
Entamoeba histolytica hypothetical protein 0.0081 0.0139 0.6418
Onchocerca volvulus 0.0035 0.0037 0.0064
Mycobacterium tuberculosis Probable lipase LipD 0.0042 0.0052 0.0915
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0038 0.0044 0.1408
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.002 0.0088
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Onchocerca volvulus 0.0503 0.107 0.3438
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Brugia malayi Tyrosine-protein kinase abl-1 0.0091 0.0161 0.0472
Loa Loa (eye worm) latrophilin receptor protein 2 0.0071 0.0116 0.0361
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0049
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0034 0.0322
Echinococcus granulosus tyrosine protein kinase HCK 0.003 0.0027 0.0032
Echinococcus granulosus tyrosine protein kinase Src64B 0.0043 0.0055 0.0125
Trichomonas vaginalis replication factor C large subunit, putative 0.0033 0.0034 0.0055
Leishmania major hypothetical protein, conserved 0.0042 0.0052 0.0394
Plasmodium vivax E3 ubiquitin-protein ligase, putative 0.0026 0.0017 0.0039
Plasmodium falciparum zinc finger protein, putative 0.0026 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0059 0.009 0.0278
Schistosoma mansoni hypothetical protein 0.0071 0.0116 0.0323
Schistosoma mansoni hypothetical protein 0.1415 0.3079 1
Mycobacterium leprae Probable lipase LipE 0.0042 0.0052 1
Echinococcus granulosus GPCR family 2 0.0071 0.0116 0.0323
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0052 0.0336
Schistosoma mansoni hypothetical protein 0.0071 0.0116 0.0323
Trichomonas vaginalis ferritin, putative 0.0038 0.0044 0.0089
Echinococcus multilocularis geminin 0.0193 0.0386 0.0369
Plasmodium falciparum ataxin-2 like protein, putative 0.0058 0.0088 0.027
Entamoeba histolytica Activator 1 140 kDa subunit, putative 0.0033 0.0034 0.0888
Echinococcus granulosus p2X purinoceptor 4 0.0074 0.0124 0.0349
Mycobacterium tuberculosis Bacterioferritin BfrB 0.0038 0.0044 0.0765
Brugia malayi hypothetical protein 0.0033 0.0034 0.0055
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0094
Trichomonas vaginalis maltase-glucoamylase, putative 0.0038 0.0044 0.0088
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Giardia lamblia E3 ubiquitin ligase for Rad6p required for the ubiquitination of histone H2B 0.0026 0.0017 0.2725
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0094
Schistosoma mansoni hypothetical protein 0.0046 0.0063 0.0149
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Loa Loa (eye worm) hypothetical protein 0.0503 0.107 0.3464
Plasmodium vivax replication factor C subunit 1, putative 0.0033 0.0034 0.0094
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0055 0.0125
Echinococcus multilocularis Niemann Pick C1 protein 0.0112 0.0208 0.0191
Brugia malayi ATP dependent DNA ligase C terminal region family protein 0.0033 0.0034 0.0055
Loa Loa (eye worm) hypothetical protein 0.0035 0.0037 0.0103
Schistosoma mansoni hypothetical protein 0.0081 0.0139 0.0399
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0058 0.0544
Loa Loa (eye worm) RING finger protein 20 0.0026 0.0017 0.0039
Echinococcus multilocularis dna polymerase kappa 0.0044 0.0058 0.0041
Loa Loa (eye worm) transcription factor SMAD2 0.0131 0.0249 0.0794
Brugia malayi Tyrosine-protein kinase abl-1 0.0123 0.0232 0.0703
Schistosoma mansoni tyrosine kinase 0.0043 0.0055 0.0125
Leishmania major hypothetical protein, conserved 0.0503 0.107 1
Echinococcus granulosus p2X purinoceptor 4 0.0074 0.0124 0.0349
Schistosoma mansoni ferritin 0.0038 0.0044 0.0089
Trypanosoma cruzi hypothetical protein, conserved 0.0503 0.107 1
Schistosoma mansoni hypothetical protein 0.0193 0.0386 0.1204
Brugia malayi beta-lactamase family protein 0.0042 0.0052 0.0116
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Echinococcus granulosus neutral alpha glucosidase AB 0.0038 0.0044 0.0088
Brugia malayi beta-lactamase 0.0042 0.0052 0.0116
Entamoeba histolytica hypothetical protein 0.0081 0.0139 0.6418
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0043 0.0055 0.0125
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0037 0.0064
Chlamydia trachomatis DNA ligase 0.0033 0.0034 0.0094
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0052 0.0116
Loa Loa (eye worm) hypothetical protein 0.0042 0.0052 0.0154
Trypanosoma cruzi hypothetical protein, conserved 0.0042 0.0052 0.0336
Plasmodium falciparum trophozoite exported protein 1 0.0026 0.0017 0.0039
Mycobacterium tuberculosis Probable lipase LipE 0.0042 0.0052 0.0915
Loa Loa (eye worm) hypothetical protein 0.0048 0.0067 0.02
Echinococcus multilocularis microtubule associated protein 2 0.0694 0.1491 0.1477
Trypanosoma cruzi hypothetical protein, conserved 0.0038 0.0044 0.0255
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0027 0.002 0.0321
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Leishmania major hypothetical protein 0.0026 0.0017 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Plasmodium falciparum replication factor C subunit 1, putative 0.0033 0.0034 0.0094
Echinococcus granulosus zinc finger protein Ran binding 0.0503 0.107 0.3438
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Brugia malayi RNA binding protein 0.0145 0.0281 0.0862
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.1415 0.3079 1
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0042 0.0052 0.8907
Trypanosoma cruzi PAB1-binding protein , putative 0.0058 0.0088 0.0675
Toxoplasma gondii poly(ADP-ribose) polymerase catalytic domain-containing protein 0.0033 0.0034 0.0055
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0043 0.0055 0.0038
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0058 0.0391
Loa Loa (eye worm) hypothetical protein 0.005 0.007 0.0212
Echinococcus granulosus p2X purinoceptor 4 0.0074 0.0124 0.0349
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Echinococcus multilocularis tyrosine protein kinase HCK 0.003 0.0027 0.001
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0503 0.107 1
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0503 0.107 0.3438
Brugia malayi hypothetical protein 0.0081 0.0139 0.0399
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0033 0.0034 0.0055
Brugia malayi Zn-finger in Ran binding protein and others containing protein 0.0503 0.107 0.3438
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0223 0.0452 0.1454
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0081 0.0139 0.0122
Schistosoma mansoni tyrosine kinase 0.0043 0.0055 0.0125
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.002 0.2826
Echinococcus multilocularis tyrosine protein kinase Blk 0.0037 0.0041 0.0024
Entamoeba histolytica protein kinase, putative 0.003 0.0027 0.0515
Trichomonas vaginalis DNA polymerase eta, putative 0.0044 0.0058 0.0135
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0033 0.0034 0.0055
Schistosoma mansoni hypothetical protein 0.0193 0.0386 0.1204
Mycobacterium tuberculosis Probable bacterioferritin BfrA 0.0038 0.0044 0.0765
Trypanosoma brucei glucosidase, putative 0.0038 0.0044 0.041
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Toxoplasma gondii ran binding protein 0.0503 0.107 0.3438
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0052 0.0116
Trichomonas vaginalis D-aminoacylase, putative 0.0042 0.0052 0.0116
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0281 0.0862
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0044 0.0088
Loa Loa (eye worm) hypothetical protein 0.0152 0.0296 0.0948
Loa Loa (eye worm) hypothetical protein 0.054 0.1151 0.3728
Onchocerca volvulus Huntingtin homolog 0.0134 0.0257 0.0783
Mycobacterium leprae PROBABLE BACTERIOFERRITIN BFRA 0.0038 0.0044 0.7485
Echinococcus granulosus ferritin 0.0038 0.0044 0.0089
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0042 0.0052 0.0116
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0094
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0038 0.0044 0.0088
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0043 0.0055 0.0038
Echinococcus multilocularis tyrosine protein kinase Srms 0.0037 0.0041 0.0024
Trypanosoma brucei DNA polymerase IV, putative 0.0044 0.0058 0.0544
Echinococcus granulosus SWI:SNF matrix associated 0.1415 0.3079 1
Echinococcus granulosus geminin 0.0193 0.0386 0.1204
Echinococcus granulosus histone lysine methyltransferase setb 0.0035 0.0037 0.0064
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Schistosoma mansoni ferritin 0.0038 0.0044 0.0089
Plasmodium falciparum zinc finger Ran-binding domain-containing protein 2, putative 0.0503 0.107 0.3464
Schistosoma mansoni ferritin 0.0038 0.0044 0.0089
Entamoeba histolytica acyl-CoA synthetase, putative 0.0027 0.002 0.0159
Onchocerca volvulus 0.0033 0.0034 0.0055
Loa Loa (eye worm) hypothetical protein 0.0027 0.002 0.0049
Trypanosoma brucei BRCA1 C Terminus (BRCT) domain containing protein, putative 0.0033 0.0034 0.0317
Echinococcus multilocularis tar DNA binding protein 0.0145 0.0281 0.0264
Schistosoma mansoni survival motor neuron protein 0.011 0.0203 0.0609
Mycobacterium tuberculosis Probable esterase LipL 0.0042 0.0052 0.0915
Mycobacterium tuberculosis Probable hydrolase 0.0042 0.0052 0.0915
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Trypanosoma brucei ring finger containing protein 0.0026 0.0017 0.0159
Echinococcus multilocularis protein dispatched 1 0.0055 0.0082 0.0065
Echinococcus multilocularis beta LACTamase domain containing family member 0.0042 0.0052 0.0035
Mycobacterium ulcerans lipase LipD 0.0042 0.0052 0.8907
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Brugia malayi Pax transcription activation domain interacting protein 0.0033 0.0034 0.0055
Trypanosoma brucei Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0503 0.107 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0027 0.002 0.0321
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0026 0.0018 0.0002
Mycobacterium tuberculosis Conserved protein 0.0042 0.0052 0.0915
Wolbachia endosymbiont of Brugia malayi bacterioferritin/cytochrome b1 0.0038 0.0044 1
Schistosoma mansoni chromosome transmission fidelity factor 0.0033 0.0034 0.0055
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0281 0.0862
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0038 0.0044 0.0126
Echinococcus multilocularis ring and YY1 binding protein 0.0503 0.107 0.1055
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0034 0.0055
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Giardia lamblia Kinase, NEK 0.0026 0.0017 0.2725
Echinococcus granulosus expressed protein 0.0038 0.0044 0.0089
Brugia malayi Calcitonin receptor-like protein seb-1 0.0223 0.0452 0.142
Brugia malayi Pre-SET motif family protein 0.0035 0.0037 0.0064
Schistosoma mansoni ferritin 0.0038 0.0044 0.0089
Brugia malayi Pre-SET motif family protein 0.0241 0.0491 0.1549
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0154 0.0301 0.0927
Brugia malayi hypothetical protein 0.0058 0.0088 0.0232
Echinococcus granulosus ring and YY1 binding protein 0.0503 0.107 0.3438
Giardia lamblia Hypothetical protein 0.0026 0.0017 0.2725
Giardia lamblia Kinase, NEK 0.0026 0.0017 0.2725
Echinococcus multilocularis ferritin 0.0038 0.0044 0.0027
Toxoplasma gondii LsmAD domain-containing protein 0.0058 0.0088 0.0232
Schistosoma mansoni hypothetical protein 0.0152 0.0296 0.0912
Brugia malayi hypothetical protein 0.054 0.1151 0.3704
Echinococcus granulosus Zinc finger RanBP2 type 0.0503 0.107 0.3438
Schistosoma mansoni hypothetical protein 0.0071 0.0116 0.0323
Entamoeba histolytica hypothetical protein 0.0033 0.0034 0.0888
Plasmodium vivax E3 ubiquitin-protein ligase RNF5, putative 0.0026 0.0017 0.0039
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Trypanosoma cruzi Zn-finger in Ran binding protein and others, putative 0.0503 0.107 1
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0026 0.0017 0.000000010415
Echinococcus granulosus microtubule associated protein 2 0.0694 0.1491 0.4814
Onchocerca volvulus 0.005 0.007 0.0174
Mycobacterium ulcerans DNA polymerase IV 0.0044 0.0058 1
Echinococcus multilocularis tyrosine protein kinase ABL1 0.0208 0.0419 0.0403
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger) containing protein, putative 0.0026 0.0017 0.0159
Echinococcus granulosus tar DNA binding protein 0.0145 0.0281 0.0862
Onchocerca volvulus 0.011 0.0203 0.0609
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Schistosoma mansoni transcription factor LCR-F1 0.0081 0.0139 0.0399
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0114 0.0211 0.0635
Echinococcus granulosus replication factor c subunit 1 0.0033 0.0034 0.0055
Echinococcus multilocularis Nuclear pore complex protein Nup153 0.0503 0.107 0.1055
Schistosoma mansoni hypothetical protein 0.0503 0.107 0.3438
Loa Loa (eye worm) hypothetical protein 0.0042 0.0052 0.0154
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Trichomonas vaginalis conserved hypothetical protein 0.1415 0.3079 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0052 0.0116
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0112 0.0208 1
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0266 0.0547 1
Onchocerca volvulus 0.0274 0.0565 0.1789
Trypanosoma brucei hypothetical protein, conserved 0.0042 0.0052 0.049
Mycobacterium tuberculosis Conserved protein 0.0042 0.0052 0.0915
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0052 0.0154
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0154 0.0301 0.0284
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.011 0.0203 0.0609
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0071 0.0116 0.0323
Brugia malayi CHE-14 protein 0.0048 0.0067 0.0162
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Schistosoma mansoni topbp1 0.0033 0.0034 0.0055
Brugia malayi Glycosyl hydrolases family 31 protein 0.0038 0.0044 0.0088
Plasmodium falciparum E3 ubiquitin-protein ligase, putative 0.0026 0.0017 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0033 0.0034 0.0161
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.002 0.2826
Trypanosoma brucei PAB1-binding protein , putative 0.0058 0.0088 0.0823
Giardia lamblia Hypothetical protein 0.0026 0.0017 0.2725
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0044 0.0088
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Trypanosoma brucei DNA repair protein, putative 0.0026 0.0017 0.0159
Schistosoma mansoni zinc finger protein 0.0503 0.107 0.3438
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0044 0.0058 0.0135
Leishmania major hypothetical protein, conserved 0.0503 0.107 1
Schistosoma mansoni mind bomb 0.0026 0.0017 0.000000010415
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0034 0.0055
Giardia lamblia Hypothetical protein 0.0026 0.0017 0.2725
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0043 0.0055 0.0038
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0055 0.0038
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0044 0.0088
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0037 0.0041 0.0079
Mycobacterium ulcerans acyl-CoA synthetase 0.0027 0.002 0.2826
Brugia malayi hypothetical protein 0.0026 0.0017 0.000000010415
Echinococcus multilocularis SWI:SNF matrix associated 0.1415 0.3079 0.3067
Trichomonas vaginalis RNA polymerase II ctd phosphatase, putative 0.0033 0.0034 0.0055
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0042 0.0052 0.0116
Trichomonas vaginalis esterase, putative 0.0042 0.0052 0.0116
Schistosoma mansoni topbp1 0.0033 0.0034 0.0055
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Echinococcus multilocularis Zinc finger, RanBP2 type 0.0503 0.107 0.1055
Trypanosoma cruzi FHA domain containing protein, putative 0.0033 0.0034 0.0161
Schistosoma mansoni fusion 0.0503 0.107 0.3438
Schistosoma mansoni apoferritin-2 0.0038 0.0044 0.0089
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0043 0.0055 0.0038
Schistosoma mansoni microtubule-associated protein tau 0.0694 0.1491 0.4814
Leishmania major 4-coumarate:coa ligase-like protein 0.0027 0.002 0.0088
Echinococcus granulosus Protein patched homolog 1 0.0048 0.0067 0.0162
Loa Loa (eye worm) TAR-binding protein 0.0145 0.0281 0.0898
Echinococcus multilocularis survival motor neuron protein 1 0.054 0.1151 0.1136
Echinococcus multilocularis p2X purinoceptor 4 0.0074 0.0124 0.0107
Echinococcus granulosus tyrosine protein kinase Src42A 0.0043 0.0055 0.0125
Schistosoma mansoni cellular tumor antigen P53 0.005 0.007 0.0174
Brugia malayi Glycosyl hydrolases family 31 protein 0.017 0.0336 0.1041
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0071 0.0116 0.0099
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0034 0.0055
Treponema pallidum bacterioferrin (TpF1) 0.0038 0.0044 1
Trichomonas vaginalis chromosome transmission fidelity factor, putative 0.0033 0.0034 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0042 0.0052 0.0116
Schistosoma mansoni hypothetical protein 0.0046 0.0063 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0023 0.0011 0.01
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0071 0.0116 0.0323
Plasmodium vivax SET domain protein, putative 0.0035 0.0037 0.0103
Plasmodium falciparum E3 ubiquitin-protein ligase RNF5, putative 0.0026 0.0017 0.0039
Leishmania major DNA repair protein-like protein 0.0026 0.0017 0.006
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0035 0.0037 0.0064
Trichomonas vaginalis ankyrin, putative 0.0026 0.0017 0.000000010415
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0154 0.0301 0.0927
Schistosoma mansoni RNA binding protein 0.0503 0.107 0.3438
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0043 0.0055 0.0125
Trypanosoma brucei DNA polymerase IV, putative 0.0037 0.0043 0.0398
Schistosoma mansoni P2X receptor subunit 0.0074 0.0124 0.0349
Brugia malayi polk-prov protein 0.0034 0.0034 0.0057
Echinococcus granulosus Niemann Pick C1 protein 0.0112 0.0208 0.0622
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0055 0.0125
Schistosoma mansoni ferritin light chain 0.0038 0.0044 0.0089
Trichomonas vaginalis ankyrin repeat domain protein, putative 0.0026 0.0017 0.000000010415
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0094
Leishmania major hypothetical protein, conserved 0.0503 0.107 1
Brugia malayi Cytochrome P450 family protein 0.0029 0.0024 0.0022
Loa Loa (eye worm) hypothetical protein 0.0112 0.0208 0.0659
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Brugia malayi protein-tyrosine kinase 0.0037 0.0041 0.0079
Trypanosoma cruzi DNA polymerase kappa, putative 0.0044 0.0058 0.0391
Loa Loa (eye worm) hypothetical protein 0.0071 0.0116 0.0361
Echinococcus multilocularis GPCR, family 2 0.0071 0.0116 0.0099
Echinococcus granulosus beta LACTamase domain containing family member 0.0042 0.0052 0.0116
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0035 0.0037 0.0064
Schistosoma mansoni hypothetical protein 0.1415 0.3079 1
Chlamydia trachomatis SWIB complex protein 0.1415 0.3079 1
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0038 0.0044 0.0088
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Schistosoma mansoni hypothetical protein 0.011 0.0203 0.0609
Onchocerca volvulus 0.0042 0.0052 0.0116
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0035 0.0037 0.002
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0281 0.0862
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0043 0.0055 0.0038
Echinococcus multilocularis expressed conserved protein 0.0105 0.0193 0.0176
Trypanosoma brucei Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Trypanosoma cruzi hypothetical protein, conserved 0.0503 0.107 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0154 0.0301 0.0284
Brugia malayi topoisomerase 0.0033 0.0034 0.0055
Loa Loa (eye worm) hypothetical protein 0.0033 0.0034 0.0094
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Entamoeba histolytica hypothetical protein 0.0081 0.0139 0.6418
Schistosoma mansoni hypothetical protein 0.1415 0.3079 1
Onchocerca volvulus 0.1415 0.3079 1
Echinococcus multilocularis tyrosine protein kinase Abl 0.0091 0.0161 0.0145
Echinococcus multilocularis protein patched 0.0048 0.0067 0.005
Trypanosoma cruzi WLM domain containing protein, putative 0.0503 0.107 1
Toxoplasma gondii Zn-finger in Ran binding protein and others domain-containing protein 0.0503 0.107 0.3438
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.1415 0.3079 1
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Onchocerca volvulus 0.0027 0.002 0.001
Trypanosoma brucei SNF2 family N-terminal domain/Ring finger domain containing protein, putative 0.0026 0.0017 0.0159
Trichomonas vaginalis ankyrin repeat-containing protein, putative 0.0026 0.0017 0.000000010415
Trypanosoma cruzi hypothetical protein, conserved 0.0503 0.107 1
Leishmania major hypothetical protein, conserved 0.0503 0.107 1
Onchocerca volvulus 0.0503 0.107 0.3438
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0081 0.0139 0.0399
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0023 0.0011 0.0149
Trypanosoma brucei DNA polymerase kappa, putative 0.0044 0.0058 0.0544
Loa Loa (eye worm) TK protein kinase 0.0037 0.0041 0.0118
Loa Loa (eye worm) brahma associated protein 0.1415 0.3079 1
Giardia lamblia Kinase 0.0026 0.0017 0.2725
Loa Loa (eye worm) hypothetical protein 0.0034 0.0034 0.0096
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0027 0.002 0.2826
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Trypanosoma cruzi Zn-finger in Ran binding protein and others/FYVE zinc finger, putative 0.0503 0.107 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0154 0.0301 0.0927
Giardia lamblia Zinc finger domain 0.0026 0.0017 0.2725
Loa Loa (eye worm) TK protein kinase 0.003 0.0027 0.0071
Schistosoma mansoni alpha-glucosidase 0.0147 0.0284 0.0871
Schistosoma mansoni tar DNA-binding protein 0.0145 0.0281 0.0862
Trypanosoma cruzi PAB1-binding protein , putative 0.0058 0.0088 0.0675
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0154 0.0301 0.0927
Echinococcus multilocularis SWI:SNF matrix associated 0.1415 0.3079 0.3067
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0223 0.0452 0.142
Echinococcus multilocularis Niemann Pick C1 protein 0.016 0.0314 0.0297
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Echinococcus granulosus tyrosine protein kinase Fyn 0.0043 0.0055 0.0125
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0071 0.0116 0.0099
Plasmodium vivax trophozoite exported protein 1, putative 0.0026 0.0017 0.0039
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0042 0.0052 0.0915
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Schistosoma mansoni ferritin light chain 0.0038 0.0044 0.0089
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0154 0.0301 0.0962
Schistosoma mansoni alpha glucosidase 0.0038 0.0044 0.0088
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Brugia malayi RNA recognition motif domain containing protein 0.0145 0.0281 0.0862
Echinococcus multilocularis expressed protein 0.0038 0.0044 0.0027
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.1415 0.3079 1
Giardia lamblia Protein 21.1 0.0026 0.0017 0.2725
Trypanosoma brucei DNA polymerase kappa, putative 0.0034 0.0034 0.0322
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.017 0.0336 0.1076
Echinococcus multilocularis neutral alpha glucosidase AB 0.0038 0.0044 0.0027
Giardia lamblia Hypothetical protein 0.0026 0.0017 0.2725
Trypanosoma brucei hypothetical protein, conserved 0.0503 0.107 1
Leishmania major hypothetical protein, conserved 0.0026 0.0017 0.006
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0034 0.0055
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0042 0.0052 0.0915
Entamoeba histolytica acyl-coA synthetase, putative 0.0027 0.002 0.0159
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0027 0.002 0.2826
Loa Loa (eye worm) hypothetical protein 0.0042 0.0052 0.0154
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0071 0.0116 0.0323
Trichomonas vaginalis alpha-glucosidase, putative 0.0038 0.0044 0.0088
Brugia malayi latrophilin 2 splice variant baaae 0.0152 0.0296 0.0912
Trypanosoma cruzi mitochondrial RNA binding complex 1 subunit, putative 0.0503 0.107 1
Onchocerca volvulus 0.0042 0.0052 0.0116
Schistosoma mansoni alpha-glucosidase 0.0147 0.0284 0.0871
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0027 0.002 0.2826
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Echinococcus granulosus Nuclear pore complex protein Nup153 0.0503 0.107 0.3438
Schistosoma mansoni brg-1 associated factor 0.1415 0.3079 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0017 0.0039
Plasmodium vivax DNA repair protein RAD5, putative 0.0026 0.0017 0.0039
Echinococcus multilocularis SWI:SNF matrix associated 0.1415 0.3079 0.3067
Schistosoma mansoni P2X receptor subunit 0.0074 0.0124 0.0349
Trypanosoma brucei Plus-3 domain/Zinc finger, C3HC4 type (RING finger), putative 0.0026 0.0017 0.0159
Schistosoma mansoni hypothetical protein 0.0026 0.0018 0.0002
Trichomonas vaginalis sucrase-isomaltase, putative 0.0038 0.0044 0.0088
Schistosoma mansoni hypothetical protein 0.0046 0.0063 0.0149
Leishmania major alpha glucosidase II subunit, putative 0.0038 0.0044 0.0313

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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