Detailed information for compound 542549

Basic information

Technical information
  • TDR Targets ID: 542549
  • Name: (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(2R,3S ,4S)-3,4,5-trihydroxy-5-(hydroxymethyl)tetrah ydrofuran-2-yl]methoxy]tetrahydropyran-3,4,5- triol
  • MW: 342.296 | Formula: C12H22O11
  • H donors: 8 H acceptors: 8 LogP: -4.43 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC[C@H]1O[C@H](OC[C@H]2OC([C@H]([C@@H]2O)O)(O)CO)[C@@H]([C@H]([C@@H]1O)O)O
  • InChi: 1S/C12H22O11/c13-1-4-6(15)8(17)9(18)11(22-4)21-2-5-7(16)10(19)12(20,3-14)23-5/h4-11,13-20H,1-3H2/t4-,5-,6-,7-,8+,9-,10+,11+,12?/m1/s1
  • InChiKey: PVXPPJIGRGXGCY-TZLCEDOOSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(2R,3S,4S)-3,4,5-trihydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]methoxy]tetrahydropyran-3,4,5-triol
  • (2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-[[(2R,3S,4S)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methoxy]oxane-3,4,5-triol
  • (2R,3S,4S,5R,6S)-2-methylol-6-[[(2R,3S,4S)-3,4,5-trihydroxy-5-methylol-tetrahydrofuran-2-yl]methoxy]tetrahydropyran-3,4,5-triol
  • isomaltulose
  • 13718-94-0
  • 15132-06-6
  • STOCK1N-68373
  • CHEBI:18394
  • 6-O-alpha-D-Glucopyranosyl-D-fructofuranose
  • C01742
  • Palatinose

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0019 0.0021
Brugia malayi Steroid receptor seven-up type 2 0.0061 0.0116 0.1338
Echinococcus multilocularis neuropeptide receptor A26 0.065 0.1465 0.3119
Brugia malayi ecdysteroid receptor 0.0061 0.0116 0.1338
Plasmodium falciparum flap endonuclease 1 0.0026 0.0035 0.2041
Brugia malayi TAR-binding protein 0.0063 0.012 0.1394
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0061 0.0116 0.1338
Brugia malayi neuropeptide F receptor 0.0144 0.0307 0.3616
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0014 0.0593
Schistosoma mansoni tar DNA-binding protein 0.0063 0.012 0.0258
Schistosoma mansoni RAR-like nuclear receptor 0.0061 0.0116 0.0247
Echinococcus multilocularis protein patched 0.0084 0.0168 0.0341
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Echinococcus granulosus peregrin 0.0029 0.0043 0.0072
Loa Loa (eye worm) histone methyltransferase 0.0028 0.0041 0.0453
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0095 0.0194 0.0396
Echinococcus multilocularis allatostatin A receptor 0.0144 0.0307 0.0639
Schistosoma mansoni cpg binding protein 0.0088 0.0179 0.0382
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Echinococcus multilocularis orexin receptor type 2 0.0144 0.0307 0.0639
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.4354
Echinococcus granulosus 7TM GPCR rhodopsin 0.0144 0.0307 0.0639
Plasmodium falciparum phd finger protein, putative 0.0029 0.0043 0.2461
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.002 0.1022
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.002 0.0201
Entamoeba histolytica peptidyl-prolyl cis-trans isomerase, putative 0.0032 0.005 0.0656
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0061 0.0116 0.0247
Loa Loa (eye worm) hypothetical protein 0.0015 0.0009 0.0073
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0071 0.014 0.1627
Echinococcus granulosus lysosomal alpha glucosidase 0.0322 0.0715 0.1512
Loa Loa (eye worm) intermediate filament protein 0.003 0.0044 0.0485
Schistosoma mansoni zinc finger protein 0.0029 0.0042 0.009
Onchocerca volvulus 0.0243 0.0533 0.8037
Echinococcus granulosus peptide allatostatin:somatostatin 0.0144 0.0307 0.0639
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0035 0.0279
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0061 0.0116 0.0229
Brugia malayi nuclear hormone receptor family member odr-7 0.0029 0.0042 0.0461
Trichomonas vaginalis helicase, putative 0.002 0.0022 0.0399
Loa Loa (eye worm) RecQ helicase 0.0045 0.0079 0.0903
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0029 0.0043
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0122 0.0256 0.0242
Schistosoma mansoni alpha-glucosidase 0.0277 0.0612 0.1308
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0004 0.0012
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0029 0.0042 0.0071
Loa Loa (eye worm) hypothetical protein 0.0295 0.0653 0.773
Schistosoma mansoni hypothetical protein 0.0048 0.0086 0.0184
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.1338
Brugia malayi PHD-finger family protein 0.0015 0.0009 0.0073
Schistosoma mansoni hypothetical protein 0.0082 0.0164 0.0351
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Onchocerca volvulus 0.0144 0.0307 0.4609
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0026
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.002 0.0457
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0035 0.0057
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.002 0.0043
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0037 0.1814
Brugia malayi photoreceptor-specific nuclear receptor 0.0061 0.0116 0.1338
Echinococcus multilocularis protein dispatched 1 0.0095 0.0195 0.0399
Brugia malayi Serotonin receptor 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Schistosoma mansoni steroid hormone receptor ad4bp 0.0061 0.0116 0.0247
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0555
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0037 0.0684
Toxoplasma gondii hypothetical protein 0.003 0.0044 0.0041
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0061 0.0116 0.1338
Brugia malayi Bromodomain containing protein 0.0029 0.0043 0.0468
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.002 0.0457
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0129 0.0276
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0144 0.0307 0.0639
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0035 0.1667
Trichomonas vaginalis set domain proteins, putative 0.0243 0.0533 1
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.1338
Brugia malayi nuclear hormone receptor family member nhr-6 0.0029 0.0042 0.0461
Trypanosoma brucei glucosidase, putative 0.0071 0.014 1
Loa Loa (eye worm) hypothetical protein 0.0034 0.0054 0.0601
Onchocerca volvulus Huntingtin homolog 0.0121 0.0253 0.3787
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0173 0.017
Echinococcus granulosus tm gpcr rhodopsin 0.0144 0.0307 0.0639
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0058 0.0105
Schistosoma mansoni thyroid hormone receptor 0.0189 0.041 0.0876
Trypanosoma cruzi DNA polymerase eta, putative 0.0019 0.002 0.0457
Echinococcus granulosus neuropeptide s receptor 0.065 0.1465 0.3119
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0019 0.0184
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.002 0.0024
Schistosoma mansoni aldehyde dehydrogenase 0.0067 0.0129 0.0276
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0012 0.0007
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0079 0.0903
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0028 0.0041 0.007
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0042 0.0038
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.1338
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0559
Schistosoma mansoni hypothetical protein 0.0128 0.027 0.0577
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0144 0.0307 0.3616
Echinococcus multilocularis somatostatin receptor 0.0144 0.0307 0.0639
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.005 0.2855
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.0184 0.2151
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0037 0.0684
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0555
Echinococcus multilocularis serotonin receptor 0.0144 0.0307 0.0639
Echinococcus granulosus Bcl 2 ous antagonist:killer 0.0082 0.0164 0.0333
Echinococcus multilocularis GPCR, family 2 0.0016 0.0012 0.0007
Brugia malayi Dopamine receptor protein 2 0.0144 0.0307 0.3616
Mycobacterium tuberculosis Putative ferredoxin reductase 0.011 0.0228 0.0214
Onchocerca volvulus 0.0088 0.0179 0.2658
Leishmania major trypanothione reductase 0.0048 0.0086 0.574
Echinococcus granulosus EGFP:Bcl2 fusion protein 0.0082 0.0164 0.0333
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Echinococcus granulosus neuropeptides capa receptor 0.0144 0.0307 0.0639
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0116 0.1338
Echinococcus multilocularis dnaJ subfamily B 0.1258 0.2859 0.6107
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0031 0.1338
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Schistosoma mansoni hypothetical protein 0.0082 0.0164 0.0351
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0061 0.0116 0.0247
Schistosoma mansoni lamin 0.003 0.0044 0.0094
Loa Loa (eye worm) hypothetical protein 0.0029 0.0043 0.047
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi Intermediate filament tail domain containing protein 0.003 0.0044 0.0485
Echinococcus granulosus tm gpcr rhodopsin 0.0144 0.0307 0.0639
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0128 0.027 0.0559
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi hypothetical protein 0.0029 0.0042 0.0461
Echinococcus granulosus serotonin receptor 0.0144 0.0307 0.0639
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0019 0.0021
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0042 0.2636
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0116 0.0229
Brugia malayi ORL1-like opioid receptor 0.0144 0.0307 0.3616
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0184 0.0394
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0032 0.005 0.0107
Schistosoma mansoni neuropeptide receptor 0.0144 0.0307 0.0657
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0345 0.0766 1
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0061 0.0116 0.0247
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0061 0.0116 0.0229
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0116 0.0229
Schistosoma mansoni hypothetical protein 0.0081 0.0161 0.0344
Schistosoma mansoni biogenic amine receptor 0.0144 0.0307 0.0657
Echinococcus granulosus fmrfamide receptor 0.0144 0.0307 0.0639
Loa Loa (eye worm) hypothetical protein 0.0086 0.0173 0.2018
Schistosoma mansoni hypothetical protein 0.0337 0.0748 0.1599
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0144 0.0307 0.0639
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.002 0.1022
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0014 0.0657
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0035 0.1667
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0014 0.0009 0.0001
Echinococcus multilocularis lysosomal alpha glucosidase 0.0322 0.0715 0.1512
Brugia malayi putative neuropeptide receptor NPR1 0.0144 0.0307 0.3616
Brugia malayi Muscleblind-like protein 0.0295 0.0653 0.773
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.003 0.0044 0.0485
Schistosoma mansoni nuclear receptor nhr-48 0.0029 0.0042 0.009
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0019 0.002 0.0364
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi hypothetical protein 0.0036 0.0058 0.0651
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0061 0.0116 0.1705
Echinococcus multilocularis serotonin receptor 0.0144 0.0307 0.0639
Toxoplasma gondii histone lysine methyltransferase SET1 0.0168 0.0362 0.0359
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Loa Loa (eye worm) G-protein coupled receptor 0.0144 0.0307 0.3616
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0061 0.0116 0.0229
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0035 0.0649
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0173 1
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0014 0.0008 0.0016
Loa Loa (eye worm) nuclear receptor NHR-67 0.0029 0.0042 0.0461
Echinococcus granulosus alpha 1A adrenergic receptor 0.0144 0.0307 0.0639
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0084 0.0168 0.1958
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0122 0.0256 0.0242
Plasmodium falciparum importin beta, putative 0.0029 0.0042 0.2408
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0014 0.0256
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0086 0.4906
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0195 0.0423 0.5521
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0028 0.0041 0.007
Onchocerca volvulus 0.0144 0.0307 0.4609
Schistosoma mansoni jumonji domain containing protein 0.0075 0.0149 0.0319
Echinococcus multilocularis expressed conserved protein 0.0183 0.0396 0.0829
Onchocerca volvulus 0.003 0.0044 0.0618
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0061 0.0116 0.1338
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0061 0.0116 0.0229
Brugia malayi putative neuropeptide receptor 0.0144 0.0307 0.3616
Echinococcus granulosus sterol regulatory element binding protein 0.0084 0.0168 0.0341
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Schistosoma mansoni amine GPCR 0.0144 0.0307 0.0657
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0016 0.0012 0.011
Echinococcus granulosus neuropeptide FF receptor 2 0.0144 0.0307 0.0639
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0019 0.0015
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.002 0.0006
Echinococcus multilocularis peregrin 0.0029 0.0043 0.0072
Onchocerca volvulus 0.0144 0.0307 0.4609
Onchocerca volvulus 0.0144 0.0307 0.4609
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0061 0.0116 0.1338
Loa Loa (eye worm) G-protein coupled receptor 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0173 1
Brugia malayi Flap endonuclease-1 0.0026 0.0035 0.0381
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0012 0.0105
Loa Loa (eye worm) neuropeptide F receptor 0.0144 0.0307 0.3616
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.002 0.0201
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.134
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0024 0.0033
Schistosoma mansoni growth hormone secretagogue receptor 0.0144 0.0307 0.0657
Echinococcus multilocularis survival motor neuron protein 1 0.0235 0.0514 0.1082
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.002 0.0043
Schistosoma mansoni inositol monophosphatase 0.0041 0.0069 0.0148
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0307 0.0657
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0086 0.0173 0.0351
Echinococcus granulosus microtubule associated protein 2 0.2051 0.4677 1
Brugia malayi jmjC domain containing protein 0.004 0.0068 0.0771
Entamoeba histolytica hypothetical protein 0.0023 0.0029 0.0382
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Onchocerca volvulus 0.0144 0.0307 0.4609
Brugia malayi G protein-coupled receptor F59B2.13 0.0144 0.0307 0.3616
Brugia malayi follicle stimulating hormone receptor 0.0379 0.0844 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0795
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.011 0.0228 0.0185
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0019 0.0015
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Trypanosoma brucei unspecified product 0.0019 0.002 0.1022
Schistosoma mansoni neuropeptide F-like receptor 0.0144 0.0307 0.0657
Brugia malayi nuclear hormone receptor 0.0029 0.0042 0.0461
Leishmania major alpha glucosidase II subunit, putative 0.0071 0.014 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0029 0.0042 0.009
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0593
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0116 0.1338
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0173 0.0159
Loa Loa (eye worm) hypothetical protein 0.0102 0.0211 0.2472
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0037 0.0684
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0031 0.1338
Loa Loa (eye worm) hypothetical protein 0.0295 0.0653 0.773
Schistosoma mansoni peptidase Clp (S14 family) 0.0086 0.0173 0.037
Schistosoma mansoni adenoreceptor 0.0144 0.0307 0.0657
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0144 0.0307 0.0639
Plasmodium falciparum glutathione reductase 0.0048 0.0086 0.5001
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0086 0.099
Brugia malayi G-protein coupled receptor 0.0144 0.0307 0.3616
Echinococcus multilocularis muscleblind protein 1 0.0295 0.0653 0.138
Echinococcus granulosus g protein coupled receptor 0.0144 0.0307 0.0639
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0144 0.0307 0.0639
Onchocerca volvulus Alhambra homolog 0.0029 0.0043 0.0596
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0052
Onchocerca volvulus 0.0061 0.0116 0.1705
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.002 0.0006
Brugia malayi CXXC zinc finger family protein 0.0088 0.0179 0.2085
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.002 0.1022
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.0184 0.2151
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0144 0.0307 0.0639
Schistosoma mansoni nuclear receptor 0.0029 0.0042 0.009
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0012
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0056 0.0105 0.0091
Entamoeba histolytica hypothetical protein 0.0098 0.0201 0.2622
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0079 0.1472
Loa Loa (eye worm) nuclear hormone receptor 0.0029 0.0042 0.0461
Schistosoma mansoni biogenic amine receptor 0.0144 0.0307 0.0657
Loa Loa (eye worm) DR-78 0.0029 0.0042 0.0461
Echinococcus granulosus somatostatin receptor 0.0144 0.0307 0.0639
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0061 0.0116 0.1338
Echinococcus multilocularis lamin 0.003 0.0044 0.0075
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0019 0.1079
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0184 0.0375
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0133
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0045 0.0042
Echinococcus multilocularis sterol regulatory element binding protein 0.0084 0.0168 0.0341
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0144 0.0307 0.0657
Plasmodium vivax SET domain protein, putative 0.0032 0.005 0.2769
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0061 0.0116 0.1338
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0061 0.0116 0.0247
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0144 0.0307 0.0639
Giardia lamblia DINP protein human, muc B family 0.0019 0.002 0.0076
Brugia malayi RNA binding protein 0.0063 0.012 0.1394
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0086 0.0983
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0019 0.0021
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0086 0.0173 0.013
Schistosoma mansoni survival motor neuron protein 0.0048 0.0086 0.0184
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0061 0.0116 0.0229
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.011 0.0228 0.0214
Onchocerca volvulus Protein ultraspiracle homolog 0.0061 0.0116 0.1705
Echinococcus granulosus g protein coupled receptor 0.0144 0.0307 0.0639
Brugia malayi neuropeptide F receptor 0.0144 0.0307 0.3616
Echinococcus granulosus snurportin 1 0.0305 0.0676 0.1428
Brugia malayi Glycosyl hydrolases family 31 protein 0.0027 0.0037 0.0404
Onchocerca volvulus Bile acid receptor homolog 0.0061 0.0116 0.1705
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.002 0.0457
Echinococcus multilocularis neuropeptide s receptor 0.065 0.1465 0.3119
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.003 0.0044 0.2398
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0086 0.0173 1
Schistosoma mansoni nuclear receptor 0.0029 0.0042 0.009
Onchocerca volvulus 0.0144 0.0307 0.4609
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0029 0.1185
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0029 0.0043 0.0091
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi hypothetical protein 0.0032 0.005 0.0555
Schistosoma mansoni tar DNA-binding protein 0.0063 0.012 0.0258
Brugia malayi Melatonin receptor type 1A 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0027 0.0037 0.0404
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0041 0.0069 0.0066
Loa Loa (eye worm) PHD-finger family protein 0.0029 0.0043 0.0468
Echinococcus granulosus flap endonuclease 1 0.0026 0.0035 0.0057
Trichomonas vaginalis conserved hypothetical protein 0.0033 0.0052 0.0963
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0061 0.0116 0.1338
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0042 0.0071
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0014 0.0011
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0144 0.0307 0.0639
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.005 0.0107
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0144 0.0307 0.3616
Leishmania major GTP-binding protein, putative 0.0021 0.0024 0.0795
Echinococcus granulosus histone lysine methyltransferase setb 0.0032 0.005 0.0089
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.014 0.2615
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0014 0.083
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0086 0.0173 0.0159
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0307 0.0639
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0031
Brugia malayi Pre-SET motif family protein 0.0032 0.005 0.0559
Loa Loa (eye worm) RNA binding protein 0.0063 0.012 0.1394
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0105
Mycobacterium tuberculosis Probable reductase 0.011 0.0228 0.0214
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0019 0.0057
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Entamoeba histolytica hypothetical protein 0.0036 0.0058 0.0757
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0144 0.0307 0.0639
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.1338
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Entamoeba histolytica hypothetical protein 0.0036 0.0058 0.0757
Onchocerca volvulus 0.0144 0.0307 0.4609
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0039 0.0067 0.3854
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0457
Schistosoma mansoni hypothetical protein 0.0305 0.0676 0.1445
Giardia lamblia PHD finger protein 15 0.0029 0.0043 0.0375
Loa Loa (eye worm) TAR-binding protein 0.0063 0.012 0.1394
Trichomonas vaginalis conserved hypothetical protein 0.0084 0.0168 0.3138
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.014 0.2615
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Echinococcus granulosus importin subunit beta 1 0.0029 0.0042 0.007
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0144 0.0307 0.0639
Echinococcus granulosus allatostatin A receptor 0.0144 0.0307 0.0639
Echinococcus multilocularis X box binding protein 1 0.0284 0.0627 0.1325
Brugia malayi Dopamine receptor protein 1 0.0144 0.0307 0.3616
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0035 0.0461
Echinococcus multilocularis Niemann Pick C1 protein 0.0279 0.0615 0.1298
Echinococcus granulosus g-protein coupled receptor 0.0144 0.0307 0.0639
Echinococcus multilocularis Niemann Pick C1 protein 0.0195 0.0423 0.0887
Trichomonas vaginalis inositol monophosphatase, putative 0.0041 0.0069 0.1283
Loa Loa (eye worm) hypothetical protein 0.0137 0.0289 0.3403
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0029 0.0043
Loa Loa (eye worm) hypothetical protein 0.0323 0.0717 0.8483
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0071 0.014 0.0137
Echinococcus granulosus ecdysone induced protein 78C 0.0061 0.0116 0.0229
Echinococcus granulosus dro:myosuppressin receptor 0.0144 0.0307 0.0639
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0022 0.0399
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0555
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.002 0.0457
Loa Loa (eye worm) hypothetical protein 0.0019 0.002 0.0201
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0012 0.0007
Schistosoma mansoni lamin 0.003 0.0044 0.0094
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0037 0.0684
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0061 0.0116 0.0229
Loa Loa (eye worm) CXXC zinc finger family protein 0.0088 0.0179 0.2085
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0012
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0032 0.005 0.0047
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.1338
Schistosoma mansoni amine GPCR 0.0144 0.0307 0.0657
Schistosoma mansoni flap endonuclease-1 0.0023 0.003 0.0063
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0014 0.0593
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.005 0.009 0.1029
Loa Loa (eye worm) hypothetical protein 0.0195 0.0423 0.4992
Leishmania major DNA polymerase eta, putative 0.0019 0.002 0.0457
Echinococcus multilocularis microtubule associated protein 2 0.2051 0.4677 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0071 0.014 0.2615
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0086 0.0072
Schistosoma mansoni opsin-like receptor 0.0144 0.0307 0.0657
Loa Loa (eye worm) hypothetical protein 0.0121 0.0253 0.2971
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0061 0.0116 0.1338
Brugia malayi orphan nuclear receptor NR2E1 0.0029 0.0042 0.0461
Echinococcus granulosus expressed protein 0.0033 0.0052 0.0092
Schistosoma mansoni tar DNA-binding protein 0.0063 0.012 0.0258
Brugia malayi glutathione reductase 0.0048 0.0086 0.099
Onchocerca volvulus 0.0144 0.0307 0.4609
Echinococcus granulosus tm gpcr rhodopsin 0.0144 0.0307 0.0639
Brugia malayi G-protein coupled receptor 0.0144 0.0307 0.3616
Echinococcus multilocularis fmrfamide receptor 0.0144 0.0307 0.0639
Schistosoma mansoni hypothetical protein 0.0034 0.0054 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.005 0.0107
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0014 0.0256
Loa Loa (eye worm) apoptosis regulator protein 0.0082 0.0164 0.1916
Schistosoma mansoni neuropeptide receptor 0.0144 0.0307 0.0657
Trypanosoma brucei DNA polymerase eta, putative 0.0019 0.002 0.1022
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0061 0.0116 0.1338
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.014 1
Loa Loa (eye worm) Pin1-type peptidyl-prolyl cis-trans isomerase 0.0033 0.0052 0.058
Schistosoma mansoni hypothetical protein 0.0081 0.0161 0.0344
Brugia malayi nuclear receptor RXR 0.0029 0.0042 0.0461
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0019 0.0184
Echinococcus granulosus dnaJ subfamily B 0.1258 0.2859 0.6107
Schistosoma mansoni tar DNA-binding protein 0.0063 0.012 0.0258
Loa Loa (eye worm) melatonin receptor type 1A 0.0144 0.0307 0.3616
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.014 0.2615
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.0184 0.0375
Brugia malayi Calcitonin receptor-like protein seb-1 0.005 0.009 0.1029
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0379 0.0844 1
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0058 0.0124
Echinococcus multilocularis ecdysone induced protein 78C 0.0061 0.0116 0.0229
Echinococcus multilocularis muscleblind protein 0.0295 0.0653 0.138
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0029 0.0042 0.009
Loa Loa (eye worm) hypothetical protein 0.0014 0.0008 0.0052
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.003 0.0044 0.1864
Echinococcus multilocularis nuclear receptor nhr 48 0.0029 0.0042 0.0071
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0056 0.0105 0.0061
Onchocerca volvulus 0.0144 0.0307 0.4609
Toxoplasma gondii pantoate-beta-alanine ligase 0.4373 1 1
Echinococcus multilocularis G protein coupled receptor 139 0.0144 0.0307 0.0639
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0067 0.0129 0.0257
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.003 0.0046 0.2509
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0086 0.0173 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0012 0.0007
Leishmania major peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative 0.0032 0.005 0.2855
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Loa Loa (eye worm) pigment dispersing factor receptor c 0.005 0.009 0.1029
Brugia malayi cytoplasmic intermediate filament protein 0.0016 0.0012 0.011
Brugia malayi RNA, U transporter 1 0.0081 0.0162 0.1894
Plasmodium falciparum lipid/sterol:H+ symporter 0.0012 0.0003 0.0186
Echinococcus multilocularis sex peptide receptor 0.0144 0.0307 0.0639
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0144 0.0307 0.4609
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0022 0.0399
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0036 0.0059 0.0015
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0037 0.0684
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Trypanosoma cruzi glycosyl hydrolase-like protein, putative 0.0027 0.0037 0.1814
Schistosoma mansoni intermediate filament proteins 0.003 0.0044 0.0094
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Toxoplasma gondii thioredoxin reductase 0.0048 0.0086 0.0083
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0015 0.001 0.0588
Echinococcus granulosus inositol monophosphatase 1 0.0041 0.0069 0.0129
Echinococcus multilocularis jumonji domain containing protein 0.004 0.0069 0.0128
Echinococcus multilocularis geminin 0.0337 0.0748 0.1583
Echinococcus granulosus biogenic amine 5HT receptor 0.0144 0.0307 0.0639
Schistosoma mansoni neuropeptide f receptor 76f 0.0144 0.0307 0.0657
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0022 0.0399
Mycobacterium tuberculosis Probable dehydrogenase 0.011 0.0228 0.0214
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.002 0.0024
Echinococcus multilocularis neuropeptide Y receptor 0.0144 0.0307 0.0639
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0144 0.0307 0.3616
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0019 0.0021
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0061 0.0116 0.0247
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0129 0.0115
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.002 0.0457
Echinococcus granulosus g protein coupled receptor 0.0144 0.0307 0.0639
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0042 0.0071
Brugia malayi jmjC domain containing protein 0.0095 0.0194 0.2265
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0144 0.0307 0.0657
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.002 0.0006
Brugia malayi PHD-finger family protein 0.0029 0.0043 0.0468
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0116 0.1338
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0035 0.189
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.4354
Loa Loa (eye worm) TYRA-2 protein 0.0144 0.0307 0.3616
Trichomonas vaginalis rotamase, putative 0.0033 0.0052 0.0963
Schistosoma mansoni ran 0.0021 0.0024 0.0052
Schistosoma mansoni hypothetical protein 0.1258 0.2859 0.6114
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.011 0.0228 0.0214
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0022 0.0399
Loa Loa (eye worm) inositol-1 0.0041 0.0069 0.0783
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0071 0.014 0.1827
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0071 0.014 0.2615
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0144 0.0307 0.0639
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0032 0.005 0.0089
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0144 0.0307 0.3616
Giardia lamblia DNA repair protein RAD52 0.0345 0.0766 1
Leishmania major DNA polymerase kappa, putative 0.0019 0.002 0.0457
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0029 0.0042 0.0071
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0144 0.0307 0.0639
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0184 0.0394
Loa Loa (eye worm) hypothetical protein 0.0019 0.0019 0.0184
Brugia malayi Apoptosis regulator proteins, Bcl-2 family protein 0.0082 0.0164 0.1916
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Loa Loa (eye worm) hypothetical protein 0.0014 0.0009 0.0067
Brugia malayi Inositol-1 0.0041 0.0069 0.0783
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0144 0.0307 0.0639
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0061 0.0116 0.0229
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Echinococcus granulosus neuropeptide receptor A26 0.065 0.1465 0.3119
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Schistosoma mansoni importin beta-1 0.0029 0.0042 0.0089
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0086 0.0173 0.0351
Schistosoma mansoni neuropeptide receptor 0.0144 0.0307 0.0657
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.1338
Brugia malayi hypothetical protein 0.0029 0.0042 0.0461
Echinococcus granulosus geminin 0.0337 0.0748 0.1583
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0144 0.0307 0.0639
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0079 0.0151
Schistosoma mansoni hypothetical protein 0.0036 0.0058 0.0124
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Trichomonas vaginalis sucrase-isomaltase, putative 0.0071 0.014 0.2615
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0014 0.0133
Schistosoma mansoni cpg binding protein 0.0093 0.019 0.0406
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0014 0.0657
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0061 0.0116 0.1338
Schistosoma mansoni biogenic amine receptor 0.0144 0.0307 0.0657
Brugia malayi hypothetical protein 0.0032 0.005 0.0555
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Mycobacterium tuberculosis Pantoate--beta-alanine ligase PanC (pantothenate synthetase) (pantoate activating enzyme) 0.4373 1 1
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0041 0.0069 0.345
Schistosoma mansoni bcl-2 homologous antagonist/killer (bak) 0.0082 0.0164 0.0351
Schistosoma mansoni retinoic acid receptor RXR 0.0061 0.0116 0.0247
Brugia malayi Niemann-Pick C1 protein precursor 0.0195 0.0423 0.4992
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0029 0.0043
Echinococcus granulosus tachykinin peptides receptor 99D 0.0144 0.0307 0.0639
Schistosoma mansoni neuropeptide receptor 0.0144 0.0307 0.0657
Brugia malayi nuclear receptor RXR 0.0032 0.005 0.0555
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0307 0.0657
Brugia malayi hypothetical protein 0.0124 0.026 0.3056
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.014 0.2615
Onchocerca volvulus 0.0144 0.0307 0.4609
Brugia malayi GnHR receptor homolog 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.1338
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0031 0.0571
Onchocerca volvulus 0.0144 0.0307 0.4609
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Onchocerca volvulus 0.0029 0.0042 0.0587
Brugia malayi hypothetical protein 0.0121 0.0253 0.2971
Trichomonas vaginalis alpha-glucosidase, putative 0.0071 0.014 0.2615
Schistosoma mansoni blooms syndrome DNA helicase 0.0035 0.0057 0.0123
Plasmodium falciparum thioredoxin reductase 0.0048 0.0086 0.5001
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0022 0.0399
Mycobacterium tuberculosis Probable oxidoreductase 0.0122 0.0256 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0061 0.0116 0.1338
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0144 0.0307 0.0657
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0032 0.005 0.0107
Schistosoma mansoni DNA helicase recq1 0.0019 0.0019 0.004
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0144 0.0307 0.0639
Loa Loa (eye worm) hypothetical protein 0.0061 0.0116 0.1338
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi Glycosyl hydrolases family 31 protein 0.0071 0.014 0.1627
Onchocerca volvulus 0.0029 0.0042 0.0587
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0031 0.1851
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0042 0.009
Trichomonas vaginalis ran, putative 0.0021 0.0024 0.0443
Brugia malayi CHE-14 protein 0.0084 0.0168 0.1958
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.002 0.0201
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.4354
Entamoeba histolytica deoxycytidyl transferase, putative 0.0019 0.002 0.0262
Plasmodium falciparum thioredoxin reductase 0.0017 0.0014 0.083
Echinococcus granulosus lysine specific demethylase 5A 0.004 0.0068 0.0127
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0043 0.0039
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0307 0.0639
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0144 0.0307 0.0657
Schistosoma mansoni tar DNA-binding protein 0.0063 0.012 0.0258
Schistosoma mansoni hypothetical protein 0.0144 0.0307 0.0657
Echinococcus multilocularis thyroid hormone receptor alpha 0.0189 0.041 0.0858
Plasmodium vivax glutathione reductase, putative 0.0048 0.0086 0.4906
Schistosoma mansoni hypothetical protein 0.0029 0.0043 0.0091
Echinococcus granulosus neutral alpha glucosidase AB 0.0071 0.014 0.0281
Brugia malayi nuclear receptor NHR-67 0.0029 0.0042 0.0461
Loa Loa (eye worm) hypothetical protein 0.0029 0.0043 0.0468
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Schistosoma mansoni opsin-like receptor 0.0144 0.0307 0.0657
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0555
Schistosoma mansoni hypothetical protein 0.0081 0.0161 0.0344
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0032 0.005 0.0088
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0198 0.043 0.0919
Echinococcus granulosus orexin receptor type 2 0.0144 0.0307 0.0639
Echinococcus granulosus lamin 0.003 0.0044 0.0075
Schistosoma mansoni microtubule-associated protein tau 0.2051 0.4677 1
Echinococcus granulosus neuropeptides capa receptor 0.0144 0.0307 0.0639
Echinococcus multilocularis cpg binding protein 0.0093 0.019 0.0388
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0014 0.0593
Loa Loa (eye worm) hypothetical protein 0.005 0.009 0.1032
Brugia malayi conserved hypotetical protein 0.0029 0.0042 0.0461
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0098 0.0201 0.2622
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0032 0.005 0.0107
Schistosoma mansoni rotamase 0.0033 0.0052 0.0111
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0067 0.0129 0.0257
Echinococcus granulosus dna polymerase eta 0.0019 0.002 0.0024
Echinococcus granulosus intermediate filament protein 0.003 0.0044 0.0075
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Brugia malayi RE15519p 0.0144 0.0307 0.3616
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0024 0.1245
Echinococcus multilocularis expressed protein 0.0033 0.0052 0.0092
Schistosoma mansoni hypothetical protein 0.0081 0.0161 0.0344
Plasmodium vivax importin-beta 2, putative 0.0029 0.0042 0.2265
Echinococcus multilocularis G-protein coupled receptor, putative 0.0144 0.0307 0.0639
Brugia malayi Tachykinin-like peptides receptor 99D 0.0144 0.0307 0.3616
Brugia malayi Serotonin receptor 0.0144 0.0307 0.3616
Trypanosoma cruzi peptidyl-prolyl cis-trans isomerase 0.0032 0.005 0.2855
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0014 0.0009 0.0001
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0024 0.0033
Loa Loa (eye worm) hypothetical protein 0.0121 0.0253 0.2971
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0029 0.0043
Echinococcus granulosus muscleblind protein 0.0295 0.0653 0.138
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0041 0.0069 0.0901
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0029 0.0042 0.0461
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0071 0.014 0.1827
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0188 0.0408 0.0873
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0086 0.0173 1
Loa Loa (eye worm) hypothetical protein 0.005 0.009 0.1029
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Schistosoma mansoni hypothetical protein 0.0082 0.0164 0.0351
Echinococcus multilocularis neutral alpha glucosidase AB 0.0071 0.014 0.0281
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0032 0.005 0.0089
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0144 0.0307 0.0657
Echinococcus granulosus Nuclear hormone receptor HR96 0.0029 0.0042 0.0071
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0184 0.0375
Leishmania major importin beta-1 subunit, putative 0.0023 0.0029 0.1185
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0061 0.0116 0.0229
Brugia malayi RNA recognition motif domain containing protein 0.0063 0.012 0.1394
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0032 0.005 0.0107
Schistosoma mansoni alpha glucosidase 0.0071 0.014 0.0299
Echinococcus multilocularis dna polymerase kappa 0.0019 0.002 0.0024
Echinococcus multilocularis neuropeptides capa receptor 0.0144 0.0307 0.0639
Schistosoma mansoni amine GPCR 0.0144 0.0307 0.0657
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0069 0.1283
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0029 0.0042 0.0461
Loa Loa (eye worm) hypothetical protein 0.0235 0.0514 0.6076
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0027 0.0037 0.0514
Trichomonas vaginalis alpha-glucosidase, putative 0.0027 0.0037 0.0684
Brugia malayi Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 0.0033 0.0052 0.058
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.0184 0.0375
Plasmodium falciparum glutathione reductase 0.0017 0.0014 0.083
Echinococcus multilocularis inositol monophosphatase 1 0.0041 0.0069 0.0129
Schistosoma mansoni patched 1 0.0084 0.0168 0.0359
Loa Loa (eye worm) hypothetical protein 0.0032 0.005 0.0555
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.005 0.0555
Echinococcus granulosus hypothetical protein 0.0144 0.0307 0.0639
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0251
Echinococcus granulosus peptidase Clp S14 family 0.0056 0.0105 0.0206
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0128 0.027 0.0559
Loa Loa (eye worm) jmjC domain-containing protein 0.004 0.0068 0.0771
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0042 0.0587
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0061 0.0116 0.1338
Schistosoma mansoni amine GPCR 0.0144 0.0307 0.0657
Echinococcus multilocularis musashi 0.003 0.0044 0.0075
Onchocerca volvulus 0.0144 0.0307 0.4609
Onchocerca volvulus 0.003 0.0044 0.0618
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0035 0.0381
Echinococcus multilocularis FTZ F1 alpha 0.0061 0.0116 0.0229
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0026
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.0676 0.7996
Echinococcus granulosus X box binding protein 1 0.0284 0.0627 0.1325
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0004 0.0012
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0035 0.216
Echinococcus multilocularis neuropeptide receptor 0.0144 0.0307 0.0639
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0129 0.0115
Echinococcus multilocularis neuropeptide receptor 0.0144 0.0307 0.0639
Onchocerca volvulus 0.0144 0.0307 0.4609
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi AKH receptor 0.0144 0.0307 0.3616
Loa Loa (eye worm) steroid hormone receptor 0.0061 0.0116 0.1338
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.003 0.0044 0.254
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0026
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0029 0.0042 0.0587
Echinococcus granulosus lamin dm0 0.003 0.0044 0.0075
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0014 0.083
Brugia malayi larval opioid receptor 0.0144 0.0307 0.3616
Schistosoma mansoni DNA polymerase eta 0.0019 0.002 0.0043
Schistosoma mansoni hypothetical protein 0.0144 0.0307 0.0657
Echinococcus granulosus Protein patched homolog 1 0.0084 0.0168 0.0341
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0042 0.2636
Schistosoma mansoni amine GPCR 0.0144 0.0307 0.0657
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Echinococcus granulosus Niemann Pick C1 protein 0.0279 0.0615 0.1298
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0144 0.0307 0.0639
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0061 0.0116 0.0229
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0806 0.1824 0.3889
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Trichomonas vaginalis rotamase, putative 0.0032 0.005 0.0929
Schistosoma mansoni inositol monophosphatase 0.0041 0.0069 0.0148
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0063 0.012 0.1394
Schistosoma mansoni biogenic amine (5HT) receptor 0.0144 0.0307 0.0657
Schistosoma mansoni coup transcription factor 0.0061 0.0116 0.0247
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0042 0.0461
Schistosoma mansoni alpha-1 adrenergic receptor 0.0144 0.0307 0.0657
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0056 0.0105 0.0091
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0144 0.0307 0.0657
Loa Loa (eye worm) neuropeptide F receptor 0.0144 0.0307 0.3616
Brugia malayi Dopamine receptor 0.0144 0.0307 0.3616
Echinococcus granulosus expressed conserved protein 0.0183 0.0396 0.0829
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0031 0.0407
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0027 0.0037 0.0485
Onchocerca volvulus 0.0048 0.0086 0.1253
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.03 0.0663 0.7845
Echinococcus multilocularis g protein coupled receptor 0.0144 0.0307 0.0639
Onchocerca volvulus 0.03 0.0663 1
Schistosoma mansoni ran 0.0021 0.0024 0.0052
Schistosoma mansoni DNA helicase recq5 0.0019 0.0019 0.004
Mycobacterium ulcerans aldehyde dehydrogenase 0.0067 0.0129 0.0115
Echinococcus multilocularis lysosomal alpha glucosidase 0.0322 0.0715 0.1512
Echinococcus granulosus neuropeptide Y receptor 0.0144 0.0307 0.0639
Echinococcus multilocularis lysine specific demethylase 5A 0.0035 0.0057 0.0102
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0061 0.0116 0.1338
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0086 0.0173 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0144 0.0307 0.0657
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Brugia malayi Nuclear hormone receptor-like 1 0.0061 0.0116 0.1338
Brugia malayi nuclear receptor NHR-88 0.0061 0.0116 0.1338
Trichomonas vaginalis DNA polymerase eta, putative 0.0019 0.002 0.0364
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0086 0.574
Echinococcus granulosus neuropeptide receptor 0.0144 0.0307 0.0639
Echinococcus multilocularis neuropeptide FF receptor 2 0.0144 0.0307 0.0639
Echinococcus multilocularis neuropeptides capa receptor 0.0144 0.0307 0.0639
Echinococcus granulosus nuclear receptor nhr 48 0.0029 0.0042 0.0071
Echinococcus granulosus PHD finger protein rhinoceros 0.0029 0.0043 0.0072
Echinococcus multilocularis snurportin 1 0.0305 0.0676 0.1428
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0061 0.0116 0.0247
Onchocerca volvulus 0.0186 0.0403 0.6064
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0027 0.0037 0.0684
Brugia malayi F/Y-rich N-terminus family protein 0.0038 0.0062 0.0702
Schistosoma mansoni apoptosis regulator bax 0.0082 0.0164 0.0351
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0024 0.0795
Onchocerca volvulus 0.0144 0.0307 0.4609
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0043 0.0074
Brugia malayi Importin beta-1 subunit 0.0029 0.0042 0.0457
Echinococcus multilocularis PHD finger protein rhinoceros 0.0029 0.0043 0.0072
Echinococcus multilocularis EGFP:Bcl2 fusion protein 0.0082 0.0164 0.0333
Echinococcus multilocularis rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0144 0.0307 0.0639
Echinococcus granulosus dna polymerase kappa 0.0019 0.002 0.0024
Brugia malayi sulfakinin receptor protein 0.0144 0.0307 0.3616
Echinococcus multilocularis neuropeptide Y receptor 0.0144 0.0307 0.0639
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0061 0.0116 0.1338
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0144 0.0307 0.0639
Echinococcus multilocularis g-protein coupled receptor 0.0144 0.0307 0.0639
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0032 0.005 0.0088
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0001 0.00000000032928
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0032 0.005 0.0555
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Trypanosoma brucei trypanothione reductase 0.0048 0.0086 0.5993
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0041 0.0069 0.1283
Onchocerca volvulus Huntingtin homolog 0.0121 0.0253 0.3787
Entamoeba histolytica hypothetical protein 0.0036 0.0058 0.0757
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0068 0.0146
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.002 0.0022 0.0399
Echinococcus multilocularis Bcl 2 ous antagonist:killer 0.0082 0.0164 0.0333
Echinococcus granulosus neuropeptide Y receptor 0.0144 0.0307 0.0639
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0086 0.0173 0.017
Echinococcus multilocularis tar DNA binding protein 0.0063 0.012 0.0239
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0144 0.0307 0.3616
Brugia malayi ecdysone receptor 0.0029 0.0042 0.0461
Echinococcus multilocularis dna polymerase eta 0.0019 0.002 0.0024
Loa Loa (eye worm) hypothetical protein 0.0084 0.0168 0.1958
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0061 0.0116 0.0229
Echinococcus granulosus bloom syndrome protein 0.0045 0.0079 0.0151
Loa Loa (eye worm) glutathione reductase 0.0048 0.0086 0.099
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0067 0.0129 0.9118
Brugia malayi intermediate filament protein 0.003 0.0044 0.0485
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0029 0.0042 0.0071
Echinococcus granulosus 7tm_1 domain containing protein 0.0144 0.0307 0.0639
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0042 0.007
Brugia malayi Thioredoxin reductase 0.0048 0.0086 0.099
Echinococcus granulosus biogenic amine 5HT receptor 0.0144 0.0307 0.0639
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0029 0.0042 0.0071
Onchocerca volvulus 0.0032 0.005 0.0712
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0122 0.0256 0.0213
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.011 0.0228 0.0214
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Echinococcus granulosus jumonji domain containing protein 0.004 0.0069 0.0128
Onchocerca volvulus 0.0144 0.0307 0.4609
Schistosoma mansoni histamine h1 receptor 0.0144 0.0307 0.0657
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0144 0.0307 0.0639
Echinococcus granulosus rhodopsin orphan GPCR 0.0144 0.0307 0.0639
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0535
Brugia malayi Glycosyl hydrolases family 31 protein 0.0322 0.0715 0.846
Plasmodium vivax hypothetical protein, conserved 0.0029 0.0043 0.2318
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0058 0.0105
Echinococcus granulosus GPCR family 2 0.0016 0.0012 0.0007
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0144 0.0307 0.0657
Plasmodium vivax hypothetical protein, conserved 0.0015 0.001 0.041
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0061 0.0116 0.1338
Toxoplasma gondii aldehyde dehydrogenase 0.0067 0.0129 0.0126
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0144 0.0307 0.0657
Brugia malayi G protein-coupled receptor 0.0144 0.0307 0.3616
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0029 0.0042 0.0071
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0035 0.0032
Echinococcus multilocularis lamin dm0 0.003 0.0044 0.0075
Onchocerca volvulus 0.0144 0.0307 0.4609
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0026
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0029 0.0535
Schistosoma mansoni alpha-glucosidase 0.0277 0.0612 0.1308
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0067 0.0129 0.0115
Brugia malayi latrophilin 2 splice variant baaae 0.0034 0.0054 0.0601
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.002 0.1022
Schistosoma mansoni hypothetical protein 0.0284 0.0627 0.1341
Leishmania major glycosyl hydrolase-like protein 0.0027 0.0037 0.1814
Schistosoma mansoni hypothetical protein 0.0144 0.0307 0.0657
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0012 0.0105
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Brugia malayi hypothetical protein 0.0144 0.0307 0.3616
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0144 0.0307 0.0639
Echinococcus granulosus neuropeptide receptor 0.0144 0.0307 0.0639
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0095 0.0194 0.0396
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0019 0.0184
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0144 0.0307 0.0657
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0086 0.0166
Echinococcus granulosus G protein coupled receptor 139 0.0144 0.0307 0.0639
Trypanosoma brucei glycosyl hydrolase-like protein 0.0027 0.0037 0.2299
Echinococcus granulosus FTZ F1 alpha 0.0061 0.0116 0.0229
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Echinococcus granulosus Niemann Pick C1 protein 0.0195 0.0423 0.0887
Schistosoma mansoni hypothetical protein 0.0144 0.0307 0.0657
Brugia malayi hypothetical protein 0.03 0.0663 0.7845
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0022 0.0399
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0061 0.0116 0.0229
Entamoeba histolytica Ran family GTPase 0.0021 0.0024 0.0318
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0061 0.0116 0.1338
Trichomonas vaginalis maltase-glucoamylase, putative 0.0027 0.0037 0.0684
Brugia malayi Probable ClpP-like protease 0.0086 0.0173 0.2018
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0029 0.0535
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.014 1
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.002 0.0006
Echinococcus granulosus thyroid hormone receptor alpha 0.0029 0.0042 0.0071
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0036 0.0059 0.0045
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.1408
Mycobacterium ulcerans pantoate--beta-alanine ligase 0.4373 1 1
Schistosoma mansoni cpg binding protein 0.0093 0.019 0.0406
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0024 0.0021
Schistosoma mansoni jumonji/arid domain-containing protein 0.004 0.0068 0.0146
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0012 0.0105
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Onchocerca volvulus 0.0144 0.0307 0.4609
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0029 0.0042 0.0071
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0214 0.0466 0.5507
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.003 0.0044 0.0485
Brugia malayi nuclear hormone receptor 0.0061 0.0116 0.1338
Schistosoma mansoni nuclear hormone receptor 0.0029 0.0042 0.009
Echinococcus granulosus tar DNA binding protein 0.0063 0.012 0.0239
Trypanosoma brucei peptidyl-prolyl cis-trans isomerase/rotamase, putative 0.0032 0.005 0.3279
Loa Loa (eye worm) hypothetical protein 0.0082 0.0164 0.1916
Schistosoma mansoni neuropeptide F-like receptor 0.0144 0.0307 0.0657
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0024 0.0251
Echinococcus granulosus sex peptide receptor 0.0144 0.0307 0.0639
Echinococcus multilocularis peptidase Clp (S14 family) 0.0056 0.0105 0.0206
Entamoeba histolytica hypothetical protein 0.0036 0.0058 0.0757
Brugia malayi Pre-SET motif family protein 0.0214 0.0466 0.5507
Echinococcus granulosus cpg binding protein 0.0093 0.019 0.0388
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0144 0.0307 0.3616
Loa Loa (eye worm) hypothetical protein 0.0144 0.0307 0.3616
Trichomonas vaginalis maltase-glucoamylase, putative 0.0071 0.014 0.2615
Loa Loa (eye worm) hypothetical protein 0.0029 0.0042 0.0461
Toxoplasma gondii PHD-finger domain-containing protein 0.0029 0.0043 0.0039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0033 0.0051 0.0108
Brugia malayi hypothetical protein 0.0235 0.0514 0.6076
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0144 0.0307 0.0657
Echinococcus granulosus survival motor neuron protein 1 0.0235 0.0514 0.1082
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Loa Loa (eye worm) jmjC domain-containing protein 0.006 0.0113 0.1309
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0041 0.0069 0.4689
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0061 0.0116 0.1338
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0041 0.0069 0.0055
Brugia malayi Nuclear hormone receptor-like 1 0.0032 0.005 0.0555
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0322 0.0715 0.846
Brugia malayi tailless protein 0.0029 0.0042 0.0461
Schistosoma mansoni thyroid hormone receptor 0.0189 0.041 0.0876
Brugia malayi steroid hormone receptor 0.0061 0.0116 0.1338
Echinococcus multilocularis fmrfamide receptor 0.0144 0.0307 0.0639
Brugia malayi nuclear receptor NHR-88 0.0029 0.0042 0.0461
Trichomonas vaginalis conserved hypothetical protein 0.002 0.0022 0.0399
Schistosoma mansoni myosin xvIII 0.0144 0.0307 0.0657
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0014 0.0011
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0086 0.0166
Echinococcus multilocularis dro:myosuppressin receptor 0.0144 0.0307 0.0639
Brugia malayi Nuclear hormone receptor E75 0.0029 0.0042 0.0461
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0012 0.0007
Onchocerca volvulus Neuropeptide F receptor homolog 0.0144 0.0307 0.4609
Schistosoma mansoni opsin-like receptor 0.0144 0.0307 0.0657
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0144 0.0307 0.0639
Toxoplasma gondii peptidylprolyl isomerase 0.0032 0.005 0.0047
Schistosoma mansoni nuclear hormone receptor 0.0061 0.0116 0.0247
Schistosoma mansoni hypothetical protein 0.0337 0.0748 0.1599
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.002 0.0022 0.0399
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.0184 0.0394
Schistosoma mansoni biogenic amine (5HT) receptor 0.0144 0.0307 0.0657
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0144 0.0307 0.0657
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0144 0.0307 0.3616
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0079 0.1472

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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