Detailed information for compound 561163

Basic information

Technical information
  • TDR Targets ID: 561163
  • Name: (2-chlorophenyl)methyl-[[4-[[(2-chlorophenyl) methylammonio]methyl]cyclohexyl]methyl]ammoni um
  • MW: 393.393 | Formula: C22H30Cl2N2++
  • H donors: 2 H acceptors: 0 LogP: 5.33 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1ccccc1C[NH2+]CC1CCC(CC1)C[NH2+]Cc1ccccc1Cl
  • InChi: 1S/C22H28Cl2N2/c23-21-7-3-1-5-19(21)15-25-13-17-9-11-18(12-10-17)14-26-16-20-6-2-4-8-22(20)24/h1-8,17-18,25-26H,9-16H2/p+2
  • InChiKey: RZRPZWGIOOZIBE-UHFFFAOYSA-P  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2-chlorophenyl)methyl-[[4-[[(2-chlorophenyl)methylazaniumyl]methyl]cyclohexyl]methyl]azanium
  • (2-chlorobenzyl)-[[4-[[(2-chlorobenzyl)ammonio]methyl]cyclohexyl]methyl]ammonium

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni coup transcription factor 0.002 0.0031 0.0101
Onchocerca volvulus 0.0709 0.2651 1
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0094 0.0333
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0064 0.0198 0.0725
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0173
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0067 0.0063
Brugia malayi Fibulin-1 precursor 0.0028 0.0062 0.0249
Entamoeba histolytica hypothetical protein 0.0036 0.009 0.0826
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0022 0.0061
Echinococcus multilocularis Polycystic kidney disease protein 0.0024 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.003 0.0067 0.0271
Onchocerca volvulus 0.0046 0.0129 0.0465
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0117
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0031 0.0117
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0037 0.0094 0.0333
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0045 0.0175
Onchocerca volvulus 0.0046 0.0129 0.0465
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0049 0.0138 0.0579
Brugia malayi Calcium binding EGF domain containing protein 0.0028 0.0062 0.0249
Echinococcus multilocularis peregrin 0.003 0.0067 0.0063
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0044 0.004
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0117
Onchocerca volvulus 0.0024 0.0044 0.0144
Toxoplasma gondii microneme protein MIC17C 0.0126 0.0433 0.0585
Toxoplasma gondii PAN domain-containing protein 0.0126 0.0433 0.0585
Brugia malayi Pre-SET motif family protein 0.0623 0.2324 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0296 0.1088
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.009 0.0296 0.0399
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0031 0.0101
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0031 0.0117
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0146 0.0509 0.4487
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0117 0.0419
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0067 0.0235
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Echinococcus multilocularis bloom syndrome protein 0.0024 0.0045 0.0041
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0031 0.0117
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0126 0.0433 0.0585
Leishmania major cytochrome p450-like protein 0.0028 0.0059 0.0472
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.005
Onchocerca volvulus 0.0126 0.0433 0.1614
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0031 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0031 0.0117
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0509 0.4487
Echinococcus granulosus histone lysine methyltransferase setb 0.009 0.0296 0.1088
Brugia malayi Glycosyl hydrolases family 31 protein 0.0166 0.0587 0.2512
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0014 0.0006 0.0054
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0146 0.0509 0.4487
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0067 0.009
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0053 0.0155 0.1327
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0043 0.0119 0.1005
Trichomonas vaginalis chromobox protein, putative 0.0043 0.0117 0.0419
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0113
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0345
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1089 0.4096
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0031 0.0101
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0031 0.0027
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0031 0.0101
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0623 0.2324 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0022 0.0061
Schistosoma mansoni egf-like domain protein 0.0028 0.0062 0.0216
Toxoplasma gondii calcium binding egf domain-containing protein 0.0028 0.0062 0.0083
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0046 0.0129 0.0466
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.009 0.0086
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0031 0.0027
Leishmania major lanosterol 14-alpha-demethylase, putative 0.0017 0.0019 0.0113
Echinococcus multilocularis RUN 0.0024 0.0044 0.004
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0166 0.0585 0.5167
Trichomonas vaginalis DNA helicase recq1, putative 0.0024 0.0045 0.0146
Loa Loa (eye worm) hypothetical protein 0.0126 0.0433 0.1849
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0059 0.0236
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0061 0.0208
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.009 0.0296 0.0292
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.005
Brugia malayi Trypsin family protein 0.0046 0.0129 0.0538
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0188 0.0688
Leishmania major 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0166 0.0585 0.5167
Loa Loa (eye worm) TK/ROR protein kinase 0.0098 0.0326 0.1389
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0129 0.0466
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.0406 0.1731
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0249
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.009 0.0321
Brugia malayi Trypsin family protein 0.0046 0.0129 0.0538
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0129 0.0466
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0309 0.1127 1
Brugia malayi RNA binding protein 0.0062 0.0188 0.0795
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0031 0.0101
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0036 0.0136
Brugia malayi hypothetical protein 0.0046 0.0129 0.0538
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0094 0.0864
Brugia malayi TAR-binding protein 0.0062 0.0188 0.0795
Brugia malayi Bloom's syndrome protein homolog 0.0024 0.0045 0.0175
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0094 0.0786
Schistosoma mansoni hypothetical protein 0.0718 0.2684 1
Echinococcus granulosus laminin 0.0028 0.0062 0.0216
Loa Loa (eye worm) PAN domain-containing protein 0.0126 0.0433 0.1849
Schistosoma mansoni alpha-glucosidase 0.0143 0.0499 0.1845
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Loa Loa (eye worm) hypothetical protein 0.0046 0.0129 0.0538
Onchocerca volvulus 0.0024 0.0044 0.0144
Onchocerca volvulus 0.0126 0.0433 0.1614
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.0011 0.0019
Schistosoma mansoni nuclear hormone receptor 0.002 0.0031 0.0101
Schistosoma mansoni hypothetical protein 0.0046 0.0129 0.0466
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Loa Loa (eye worm) hypothetical protein 0.004 0.0105 0.0437
Echinococcus multilocularis enteropeptidase 0.0046 0.0129 0.0125
Brugia malayi jmjC domain containing protein 0.0098 0.0325 0.1382
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0198 0.1716
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.0055
Brugia malayi PHD-finger family protein 0.003 0.0067 0.0271
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0024 0.0045 0.0041
Loa Loa (eye worm) PAN domain-containing protein 0.0126 0.0433 0.1849
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0031 0.0117
Schistosoma mansoni subfamily M12A unassigned peptidase (M12 family) 0.0028 0.0062 0.0216
Trichomonas vaginalis maltase-glucoamylase, putative 0.0037 0.0094 0.0333
Onchocerca volvulus Alhambra homolog 0.003 0.0067 0.023
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0045 0.006
Echinococcus granulosus transcription factor Dp 1 0.0037 0.0095 0.0341
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Schistosoma mansoni alpha glucosidase 0.0037 0.0094 0.0336
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0129 0.0466
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0022 0.0061
Loa Loa (eye worm) hypothetical protein 0.0126 0.0433 0.1849
Onchocerca volvulus 0.0126 0.0433 0.1614
Echinococcus granulosus tissue type plasminogen activator 0.0098 0.0326 0.1203
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0094 0.0333
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0031 0.0117
Onchocerca volvulus 0.0046 0.0129 0.0465
Echinococcus granulosus Tolloid protein 1 0.0028 0.0062 0.0216
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1089 0.4096
Schistosoma mansoni chromobox protein 0.0071 0.0224 0.0822
Echinococcus granulosus enteropeptidase 0.0046 0.0129 0.0466
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Trypanosoma cruzi Emopamil binding protein, putative 0.0166 0.0585 0.5167
Loa Loa (eye worm) PAN domain-containing protein 0.0126 0.0433 0.1849
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1089 0.4096
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.005
Echinococcus multilocularis chromobox protein 1 0.0071 0.0224 0.022
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0098 0.0326 1
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0064 0.0198 0.0725
Echinococcus multilocularis cpg binding protein 0.003 0.0066 0.0062
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0031 0.0117
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0086 0.0281 0.1033
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0345
Echinococcus granulosus GPCR family 2 0.0017 0.0017 0.005
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0022 0.0061
Leishmania major mitochondrial DNA polymerase beta 0.0309 0.1127 1
Echinococcus multilocularis laminin 0.0028 0.0062 0.0058
Echinococcus granulosus Mastin 0.0046 0.0129 0.0466
Echinococcus multilocularis p2X purinoceptor 4 0.0082 0.0265 0.0261
Mycobacterium tuberculosis Conserved hypothetical protein 0.0163 0.0572 1
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0046 0.0129 0.0466
Onchocerca volvulus 0.0166 0.0585 0.219
Schistosoma mansoni hypothetical protein 0.0036 0.009 0.0321
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0168 0.0227
Schistosoma mansoni cpg binding protein 0.003 0.0066 0.0232
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Toxoplasma gondii microneme protein, putative 0.0126 0.0433 0.0585
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0237 0.0854 0.3662
Toxoplasma gondii microneme protein MIC17B 0.0126 0.0433 0.0585
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0031 0.0095
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0031 0.0101
Echinococcus granulosus bloom syndrome protein 0.0024 0.0045 0.0152
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0117
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0097 0.04
Mycobacterium ulcerans hypothetical protein 0.0046 0.0129 0.1993
Leishmania major alpha glucosidase II subunit, putative 0.0037 0.0094 0.0786
Giardia lamblia PHD finger protein 15 0.003 0.0067 0.0213
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0031 0.0101
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0198 0.1716
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0117
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0249
Brugia malayi Trypsin-like protease protein 5 0.0046 0.0129 0.0538
Loa Loa (eye worm) hypothetical protein 0.0126 0.0433 0.1849
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0045 0.0345
Echinococcus multilocularis microtubule associated protein 2 0.0673 0.2512 0.2509
Schistosoma mansoni cpg binding protein 0.0028 0.006 0.0209
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.0406 0.1731
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0031 0.0101
Loa Loa (eye worm) hypothetical protein 0.0098 0.0326 0.1389
Loa Loa (eye worm) hypothetical protein 0.0046 0.0129 0.0538
Loa Loa (eye worm) multiple epidermal growth factor-like domains 6 0.0028 0.0062 0.0249
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0094 0.0786
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0155 0.0651
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0031 0.0101
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0013
Brugia malayi follicle stimulating hormone receptor 0.0237 0.0854 0.3662
Onchocerca volvulus 0.0126 0.0433 0.1614
Loa Loa (eye worm) hypothetical protein 0.0024 0.0045 0.0175
Brugia malayi CXXC zinc finger family protein 0.0028 0.006 0.0242
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0024 0.0045 0.0041
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0138 0.0501
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0031 0.0095
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0031 0.0117
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.005
Loa Loa (eye worm) bone morphogenetic protein 1b 0.0028 0.0062 0.0249
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0017 0.0057
Brugia malayi Cytochrome P450 family protein 0.0028 0.0059 0.0236
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0129 0.0125
Onchocerca volvulus Arrow homolog 0.0028 0.0062 0.0211
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0031 0.0027
Loa Loa (eye worm) hypothetical protein 0.0053 0.0155 0.0651
Brugia malayi Cytochrome P450 family protein 0.0063 0.0194 0.0818
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0119 0.1005
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0067 0.0271
Echinococcus granulosus glycoprotein Antigen 5 0.0046 0.0129 0.0466
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0031 0.0101
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0057
Entamoeba histolytica hypothetical protein 0.0036 0.009 0.0826
Toxoplasma gondii kringle domain-containing protein 0.0098 0.0326 0.0441
Echinococcus granulosus tar DNA binding protein 0.0062 0.0188 0.0688
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1089 0.4096
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0188 0.0688
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Plasmodium vivax multidomain scavenger receptor, putative 0.0024 0.0044 0.1353
Schistosoma mansoni cytochrome P450 0.0017 0.0019 0.0055
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0097 0.0346
Echinococcus granulosus chromobox protein 1 0.0071 0.0224 0.0822
Leishmania major hypothetical protein, conserved 0.0166 0.0585 0.5167
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0117
Brugia malayi Cytochrome P450 family protein 0.0028 0.0059 0.0236
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0031 0.0027
Trypanosoma cruzi Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0113
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.1127 1
Echinococcus multilocularis tissue type plasminogen activator 0.0098 0.0326 0.0322
Echinococcus granulosus neutral alpha glucosidase AB 0.0037 0.0094 0.0336
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0061 0.0208
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0031 0.0027
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0129 0.0466
Echinococcus multilocularis GPCR, family 2 0.0017 0.0017 0.0013
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0046 0.0129 0.0538
Entamoeba histolytica hypothetical protein 0.0036 0.009 0.0826
Toxoplasma gondii PAN domain-containing protein 0.1959 0.7402 1
Echinococcus granulosus Polycystic kidney disease protein 0.0024 0.0044 0.015
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0024 0.0045 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0031 0.0117
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.0325 0.0321
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0031 0.0101
Trichomonas vaginalis set domain proteins, putative 0.0709 0.2651 1
Loa Loa (eye worm) heterochromatin protein 1 0.0071 0.0224 0.095
Loa Loa (eye worm) hypothetical protein 0.0046 0.0129 0.0538
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0129 0.0466
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0037 0.0094 0.0388
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0031 0.0101
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0031 0.0117
Plasmodium falciparum phd finger protein, putative 0.003 0.0067 0.0806
Brugia malayi Doublecortin family protein 0.0024 0.0044 0.0173
Schistosoma mansoni P2X receptor subunit 0.0082 0.0265 0.0975
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0138 0.0134
Echinococcus granulosus cytochrome P450 2K1 0.0017 0.0019 0.0055
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0094 0.0333
Loa Loa (eye worm) hypothetical protein 0.009 0.0296 0.1257
Brugia malayi Glycosyl hydrolases family 31 protein 0.0014 0.0006 0.0008
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0188 0.0688
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0031 0.0117
Echinococcus granulosus geminin 0.0718 0.2684 1
Echinococcus granulosus p2X purinoceptor 4 0.0082 0.0265 0.0975
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1089 0.4096
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.005
Schistosoma mansoni rab6-interacting 0.0024 0.0044 0.015
Loa Loa (eye worm) hypothetical protein 0.0046 0.0129 0.0538
Trypanosoma cruzi hypothetical protein, conserved 0.0098 0.0326 0.2857
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0117
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0031 0.0027
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0249
Toxoplasma gondii microneme protein MIC4 0.0126 0.0433 0.0585
Echinococcus multilocularis transcription factor Dp 1 0.0037 0.0095 0.0091
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0188 0.0795
Onchocerca volvulus 0.0126 0.0433 0.1614
Onchocerca volvulus 0.002 0.0031 0.0095
Toxoplasma gondii subtilisin SUB12 0.0126 0.0433 0.0585
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0138 0.0501
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0155 0.0651
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0094 0.0333
Schistosoma mansoni jumonji domain containing protein 0.0078 0.0248 0.0912
Brugia malayi steroid hormone receptor 0.002 0.0031 0.0117
Schistosoma mansoni cpg binding protein 0.003 0.0066 0.0232
Schistosoma mansoni rab6-interacting 0.0024 0.0044 0.015
Echinococcus granulosus FTZ F1 alpha 0.002 0.0031 0.0101
Brugia malayi MH2 domain containing protein 0.0119 0.0406 0.1731
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0031 0.0117
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0046 0.0129 0.0125
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0091 0.0376
Trypanosoma brucei glucosidase, putative 0.0037 0.0094 0.0786
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0031 0.0117
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0064 0.0198 0.1821
Echinococcus granulosus peregrin 0.003 0.0067 0.0235
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0031 0.0117
Echinococcus granulosus RUN 0.0024 0.0044 0.015
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0067 0.0235
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0037 0.0094 0.0864
Echinococcus multilocularis lipoxygenase domain containing protein 0.0024 0.0044 0.004
Brugia malayi Glycosyl hydrolases family 31 protein 0.0037 0.0094 0.0388
Toxoplasma gondii PAN domain-containing protein 0.1959 0.7402 1
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0224 0.0826
Onchocerca volvulus Heterochromatin protein 1 homolog 0.004 0.0105 0.0376
Loa Loa (eye worm) cytochrome P450 family protein 0.0063 0.0194 0.0818
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0022 0.0061
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Schistosoma mansoni P2X receptor subunit 0.0082 0.0265 0.0975
Onchocerca volvulus 0.0046 0.0129 0.0465
Giardia lamblia Fructose-bisphosphate aldolase 0.0299 0.1089 1
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0188 0.0795
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0031 0.0117
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.0028 0.0062 0.0249
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0031 0.0027
Onchocerca volvulus 0.0031 0.0073 0.0252
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0309 0.1127 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0296 0.1088
Leishmania major cytochrome p450-like protein 0.0017 0.0019 0.0113
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0063 0.0192 0.0701
Brugia malayi hypothetical protein 0.0036 0.009 0.0371
Loa Loa (eye worm) PAN domain-containing protein 0.0126 0.0433 0.1849
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0064 0.0198 0.0838
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0031 0.0101
Echinococcus multilocularis fibrillin 1 0.0028 0.0062 0.0058
Onchocerca volvulus 0.0046 0.0129 0.0465
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.1089 1
Schistosoma mansoni hypothetical protein 0.0024 0.0044 0.015
Toxoplasma gondii calcium binding egf domain-containing protein 0.0028 0.0062 0.0083
Schistosoma mansoni thyroid hormone receptor 0.002 0.0031 0.0101
Toxoplasma gondii hypothetical protein 0.0126 0.0433 0.0585
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0024 0.0045 0.0152
Echinococcus multilocularis transmembrane protease serine 3 0.0046 0.0129 0.0125
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0249
Loa Loa (eye worm) RNA binding protein 0.0062 0.0188 0.0795
Trichomonas vaginalis chromobox protein, putative 0.0071 0.0224 0.0826
Onchocerca volvulus 0.0098 0.0326 0.1211
Schistosoma mansoni hypothetical protein 0.0098 0.0326 0.1203
Trypanosoma brucei cytochrome P450, putative 0.0028 0.0059 0.0472
Trichomonas vaginalis sucrase-isomaltase, putative 0.0037 0.0094 0.0333
Schistosoma mansoni microtubule-associated protein tau 0.0673 0.2512 0.9358
Echinococcus granulosus cpg binding protein 0.003 0.0066 0.0232
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0022 0.0061
Onchocerca volvulus 0.0126 0.0433 0.1614
Echinococcus multilocularis chromobox protein 1 0.0071 0.0224 0.022
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0024 0.0045 0.0175
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0037 0.0094 0.0127
Schistosoma mansoni lipoxygenase 0.01 0.0332 0.1225
Toxoplasma gondii cytochrome p450 superfamily protein 0.0017 0.0019 0.0025
Mycobacterium ulcerans hypothetical protein 0.0163 0.0572 1
Echinococcus multilocularis Mastin 0.0046 0.0129 0.0125
Toxoplasma gondii PAN domain-containing protein 0.0126 0.0433 0.0585
Trypanosoma cruzi Emopamil binding protein, putative 0.0166 0.0585 0.5167
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1089 0.4096
Schistosoma mansoni mixed-lineage leukemia protein mll 0.002 0.003 0.0095
Brugia malayi Protein kinase domain containing protein 0.0098 0.0326 0.1389
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0102 0.034 0.1253
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0031 0.0117
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0043 0.0119 0.1005
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0049 0.0138 0.0501
Loa Loa (eye worm) hypothetical protein 0.0046 0.0129 0.0538
Brugia malayi cytochrome P450 0.0017 0.0019 0.0063
Loa Loa (eye worm) PAN domain-containing protein 0.0126 0.0433 0.1849
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0045 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0031 0.0117
Loa Loa (eye worm) hypothetical protein 0.0046 0.0129 0.0538
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0031 0.0101
Loa Loa (eye worm) jmjC domain-containing protein 0.0062 0.0188 0.0791
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0067 0.009
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0146 0.0508 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.0129 0.0538
Toxoplasma gondii PAN domain-containing protein 0.0126 0.0433 0.0585
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0059 0.0472
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0111 0.0107
Loa Loa (eye worm) CYP4Cod1 0.0028 0.0059 0.0236
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0044 0.015
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.009 0.0296 0.1088
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0045 0.041
Schistosoma mansoni DNA helicase recq5 0.0024 0.0045 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0031 0.0117
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0031 0.0117
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0046 0.0129 0.0466
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0094 0.0333
Trichomonas vaginalis alpha-glucosidase, putative 0.0037 0.0094 0.0333
Loa Loa (eye worm) hypothetical protein 0.0126 0.0433 0.1849
Schistosoma mansoni polycystin 1-related 0.0024 0.0044 0.015
Trypanosoma cruzi cytochrome p450-like protein, putative 0.0017 0.0019 0.0113
Trypanosoma brucei Emopamil binding protein, putative 0.0166 0.0585 0.5167
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0045 0.0146
Plasmodium vivax hypothetical protein, conserved 0.003 0.0067 0.205
Brugia malayi Cytochrome P450 family protein 0.0017 0.0019 0.0063
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.0028 0.0062 0.0249
Loa Loa (eye worm) hypothetical protein 0.0028 0.0062 0.0249
Onchocerca volvulus 0.0126 0.0433 0.1614
Echinococcus granulosus lipoxygenase domain containing protein 0.0024 0.0044 0.015
Schistosoma mansoni hypothetical protein 0.0036 0.0091 0.0326
Brugia malayi nuclear hormone receptor 0.002 0.0031 0.0117
Loa Loa (eye worm) RecQ helicase 0.0024 0.0045 0.0175
Echinococcus multilocularis geminin 0.0718 0.2684 0.2681
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0142 0.0495 0.0491
Brugia malayi Pre-SET motif family protein 0.009 0.0296 0.1257
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0045 0.0146
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0155 0.0651
Schistosoma mansoni chromobox protein 0.0071 0.0224 0.0822
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0188 0.0185
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0031 0.0027
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.009 0.0321
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0031 0.0117
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0188 0.0688
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1089 0.4096
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0091 0.0087
Onchocerca volvulus 0.0126 0.0433 0.1614
Onchocerca volvulus 0.0028 0.006 0.0205
Brugia malayi Bromodomain containing protein 0.003 0.0067 0.0271
Echinococcus multilocularis p2X purinoceptor 4 0.0082 0.0265 0.0261
Toxoplasma gondii PAN/Apple domain-containing protein 0.0126 0.0433 0.0585
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.0325 0.1197
Echinococcus granulosus transmembrane protease serine 3 0.0046 0.0129 0.0466
Brugia malayi Kringle domain containing protein 0.0098 0.0326 0.1389
Schistosoma mansoni hypothetical protein 0.0046 0.0129 0.0466
Loa Loa (eye worm) hypothetical protein 0.0014 0.0006 0.0008
Brugia malayi nuclear receptor NHR-88 0.002 0.0031 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0031 0.0117
Brugia malayi SET domain containing protein 0.0016 0.0013 0.0038
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0064 0.0198 0.1716
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.0011 0.0019
Loa Loa (eye worm) hypothetical protein 0.0036 0.0091 0.0376
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0024 0.0045 0.0152
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0031 0.0027
Plasmodium falciparum cysteine repeat modular protein 1 0.0098 0.0326 1
Brugia malayi hypothetical protein 0.0024 0.0044 0.0173
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.006 0.0242
Toxoplasma gondii PAN domain-containing protein 0.0126 0.0433 0.0585
Schistosoma mansoni hypothetical protein 0.003 0.0067 0.0235
Schistosoma mansoni loxhd1 0.0024 0.0044 0.015
Brugia malayi hypothetical protein 0.0024 0.0044 0.0173
Schistosoma mansoni cercarial elastase (S01 family) 0.0046 0.0129 0.0466
Trypanosoma brucei Lanosterol 14-alpha demethylase 0.0017 0.0019 0.0113
Toxoplasma gondii hypothetical protein 0.0126 0.0433 0.0585
Loa Loa (eye worm) hypothetical protein 0.0031 0.0073 0.0296
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0138 0.0501
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0043 0.0117 0.0419
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0129 0.0466
Brugia malayi Trypsin family protein 0.0046 0.0129 0.0538
Echinococcus granulosus p2X purinoceptor 4 0.0082 0.0265 0.0975
Echinococcus granulosus chromobox protein 1 0.0071 0.0224 0.0822
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0031 0.0101
Schistosoma mansoni thyroid hormone receptor 0.002 0.0031 0.0101
Loa Loa (eye worm) hypothetical protein 0.0024 0.0044 0.0173
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0031 0.0101
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0299 0.1089 0.4096
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0064 0.0198 0.1716
Echinococcus granulosus lysosomal alpha glucosidase 0.0166 0.0587 0.2174
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0049 0.0138 0.0579
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0043 0.0119 0.1005
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0188 0.0688
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0015 0.0009 0.0012
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0049 0.0138 0.0501
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0587 0.0583
Echinococcus multilocularis lysosomal alpha glucosidase 0.0166 0.0587 0.0583
Onchocerca volvulus 0.0046 0.0129 0.0465
Brugia malayi ecdysteroid receptor 0.002 0.0031 0.0117
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0031 0.0117
Echinococcus granulosus microtubule associated protein 2 0.0673 0.2512 0.9358
Entamoeba histolytica hypothetical protein 0.0036 0.009 0.0826
Echinococcus multilocularis neutral alpha glucosidase AB 0.0037 0.0094 0.009
Onchocerca volvulus 0.0126 0.0433 0.1614
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.005
Onchocerca volvulus 0.0126 0.0433 0.1614
Loa Loa (eye worm) cytochrome P450 0.0017 0.0019 0.0063
Onchocerca volvulus 0.0102 0.034 0.1263
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0188 0.0795
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Echinococcus multilocularis p2X purinoceptor 4 0.0082 0.0265 0.0261
Echinococcus multilocularis Tolloid protein 1 0.0028 0.0062 0.0058
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0017 0.0057
Treponema pallidum fructose-bisphosphate aldolase 0.0299 0.1089 0.5
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0097 0.0346
Loa Loa (eye worm) hypothetical protein 0.0051 0.0148 0.062
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0111 0.04
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0049 0.0138 0.0134
Schistosoma mansoni P2X receptor subunit 0.0082 0.0265 0.0975
Echinococcus multilocularis glycoprotein Antigen 5 0.0046 0.0129 0.0125
Toxoplasma gondii microneme protein MIC17A 0.0126 0.0433 0.0585
Brugia malayi PAN domain containing protein 0.0126 0.0433 0.1849
Echinococcus multilocularis 0.0017 0.0019 0.0015
Schistosoma mansoni P2X receptor subunit 0.0082 0.0265 0.0975
Schistosoma mansoni alpha-glucosidase 0.0143 0.0499 0.1845
Leishmania major hypothetical protein, conserved 0.0098 0.0326 0.2857
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0146 0.0508 0.8855
Onchocerca volvulus 0.0126 0.0433 0.1614
Loa Loa (eye worm) hypothetical protein 0.002 0.0031 0.0117
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0022 0.0061
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0299 0.1089 1
Brugia malayi Trypsin family protein 0.0046 0.0129 0.0538
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0017 0.0057
Schistosoma mansoni lipoxygenase 0.0142 0.0495 0.1833
Trypanosoma cruzi cytochrome P450, putative 0.0028 0.0059 0.0472
Onchocerca volvulus 0.0096 0.032 0.1186
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0031 0.0095
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0045 0.0175
Plasmodium vivax SET domain protein, putative 0.009 0.0296 0.906
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.0376
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0024 0.0045 0.006
Schistosoma mansoni hypothetical protein 0.0718 0.2684 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0028 0.0059 0.0727
Loa Loa (eye worm) doublecortin family protein 0.0024 0.0044 0.0173
Schistosoma mansoni DNA helicase recq1 0.0024 0.0045 0.0152
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0031 0.0117
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0142 0.0495 0.1833
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0046 0.0129 0.0466
Brugia malayi chromobox protein homolog 3 0.004 0.0105 0.0437
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0064 0.0198 0.0194
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0166 0.0587 0.2512
Loa Loa (eye worm) hypothetical protein 0.0126 0.0433 0.1849
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0022 0.0061
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0097 0.0346
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0031 0.0117
Leishmania major cytochrome p450-like protein 0.0017 0.0019 0.0113
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0105 0.0376
Loa Loa (eye worm) hypothetical protein 0.0126 0.0433 0.1849
Toxoplasma gondii hypothetical protein 0.005 0.0143 0.0193
Trypanosoma cruzi 3-Beta-hydroxysteroid-delta(8), delta(7)-isomerase, putative 0.0166 0.0585 0.5167
Brugia malayi Heterochromatin protein 1 0.0071 0.0224 0.095
Loa Loa (eye worm) hypothetical protein 0.0126 0.0433 0.1849
Loa Loa (eye worm) cytochrome P450 family protein 0.0028 0.0059 0.0236
Echinococcus granulosus p2X purinoceptor 4 0.0082 0.0265 0.0975
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0064 0.0198 0.0838
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.009 0.0296 0.0292
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0146 0.0508 0.8855
Loa Loa (eye worm) trypsin family protein 0.0046 0.0129 0.0538
Brugia malayi jmjC domain containing protein 0.0038 0.0097 0.04
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0031 0.0101

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.