Detailed information for compound 589414

Basic information

Technical information
  • TDR Targets ID: 589414
  • Name: (2-carboxy-2,4-dihydroxy-4-oxo-butyl)-hydroxy -oxo-phosphonium
  • MW: 212.095 | Formula: C5H9O7P+
  • H donors: 4 H acceptors: 7 LogP: -2.56 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: OC(=O)CC(C(=O)O)(C[PH+](=O)O)O
  • InChi: 1S/C5H7O7P/c6-3(7)1-5(10,4(8)9)2-13(11)12/h10H,1-2H2,(H2-,6,7,8,9,11,12)/p+1
  • InChiKey: JXXFUSZZGFSADU-UHFFFAOYSA-O  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • (2-carboxy-2,4-dihydroxy-4-oxobutyl)-hydroxy-oxophosphonium
  • (2-carboxy-2,4-dihydroxy-4-oxo-butyl)-hydroxy-oxo-phosphanium
  • (2-carboxy-2,4-dihydroxy-4-keto-butyl)-hydroxy-keto-phosphonium
  • (2-carboxy-2,4-dihydroxy-4-oxobutyl)-hydroxy-oxophosphanium
  • 2-phosphinomethylmalic acid
  • 95114-79-7
  • Butanedioic acid, 2-hydroxy-2-((hydroxyphosphinyl)methyl)-, (S)-

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0258 0.0004
Schistosoma mansoni myelin transcription factor 1 myt1 0.0052 0.1049 0.1049
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.006 0.1217 0.1217
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0065 0.1333 0.1646
Echinococcus granulosus importin subunit beta 1 0.0029 0.0502 0.0502
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0052 0.1049 0.3851
Entamoeba histolytica acyl-coA synthetase, putative 0.0025 0.0402 0.1095
Schistosoma mansoni hypothetical protein 0.002 0.029 0.029
Echinococcus multilocularis lamin 0.0026 0.0432 0.0432
Schistosoma mansoni intermediate filament proteins 0.0026 0.0432 0.0432
Brugia malayi intermediate filament protein 0.0026 0.0432 0.1387
Echinococcus granulosus snurportin 1 0.031 0.7077 0.7077
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0116 0.0116
Echinococcus multilocularis histone acetyltransferase MYST2 0.0052 0.1049 0.1049
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0017 0.0209 0.0209
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.0075 0.157 0.157
Loa Loa (eye worm) hypothetical protein 0.0118 0.259 0.3621
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.157 1
Onchocerca volvulus 0.0026 0.0432 0.0136
Onchocerca volvulus Huntingtin homolog 0.0118 0.259 1
Trypanosoma brucei unspecified product 0.0019 0.0258 0.0935
Schistosoma mansoni bromodomain containing protein 0.0063 0.1298 0.1298
Echinococcus multilocularis dnaJ subfamily B 0.0435 1 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.051
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0052 0.1049 0.1049
Loa Loa (eye worm) hypothetical protein 0.0118 0.259 0.3621
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1333 0.1333
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0182 0.4069 0.4069
Echinococcus granulosus methyl CpG binding domain protein 2 0.0017 0.0209 0.0209
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0402 0.1095
Trypanosoma cruzi importin beta-1 subunit, putative 0.0024 0.0373 0.1457
Loa Loa (eye worm) hypothetical protein 0.0069 0.1426 0.1966
Schistosoma mansoni zinc finger protein 0.0015 0.0169 0.0169
Loa Loa (eye worm) MBCTL1 0.0052 0.1049 0.143
Echinococcus multilocularis dna polymerase eta 0.0043 0.0834 0.0834
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0258 0.0935
Echinococcus multilocularis polycomb protein SCMH1 0.0046 0.09 0.09
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.0075 0.157 1
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.0075 0.157 1
Toxoplasma gondii ImpB/MucB/SamB family protein 0.003 0.0533 0.0376
Echinococcus granulosus zinc finger protein 0.0021 0.0307 0.0307
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.09 0.3258
Loa Loa (eye worm) bromodomain containing protein 0.0017 0.0223 0.0255
Trypanosoma cruzi DNA polymerase eta, putative 0.003 0.0533 0.2598
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0017 0.0225 0.0225
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.0075 0.157 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0693 0.0923
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0502 0.0502
Loa Loa (eye worm) hypothetical protein 0.0026 0.0432 0.0552
Loa Loa (eye worm) hypothetical protein 0.0017 0.0225 0.0258
Loa Loa (eye worm) hypothetical protein 0.0019 0.0256 0.0301
Loa Loa (eye worm) hypothetical protein 0.0012 0.0105 0.0088
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0116 0.0116
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0046 0.09 0.2276
Loa Loa (eye worm) hypothetical protein 0.0052 0.1049 0.143
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0209 0.0209
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0402 0.1661
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0502 0.2618
Echinococcus granulosus histone lysine methyltransferase setb 0.0017 0.0225 0.0225
Schistosoma mansoni hypothetical protein 0.0192 0.4318 0.4318
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.051
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0432 0.1387
Plasmodium vivax importin-beta 2, putative 0.0029 0.0502 0.037
Treponema pallidum hypothetical protein 0.0304 0.6923 0.5
Brugia malayi Bromodomain containing protein 0.0037 0.0691 0.2422
Loa Loa (eye worm) hypothetical protein 0.0019 0.0256 0.0301
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0502 0.2618
Entamoeba histolytica acyl-CoA synthetase, putative 0.0025 0.0402 0.1095
Schistosoma mansoni hypothetical protein 0.0435 1 1
Mycobacterium ulcerans bifunctional nicotinate-nucleotide adenylyltransferase NadD/hypothetical protein 0.0304 0.6923 1
Brugia malayi ImpB/MucB/SamB family protein 0.0019 0.0258 0.0696
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0024 0.0374 0.0374
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.031 0.7077 1
Echinococcus granulosus histone acetyltransferase MYST2 0.0052 0.1049 0.1049
Brugia malayi hypothetical protein 0.0118 0.259 1
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.09 0.09
Trichomonas vaginalis conserved hypothetical protein 0.0075 0.157 1
Schistosoma mansoni hypothetical protein 0.031 0.7077 0.7077
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.0075 0.157 1
Mycobacterium ulcerans hypothetical protein 0.0025 0.0402 0.022
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.006 0.1217 0.1217
Loa Loa (eye worm) mbt repeat family protein 0.0046 0.09 0.1218
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0024 0.0374 0.0374
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.0075 0.157 0.157
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0052 0.1049 0.1049
Loa Loa (eye worm) hypothetical protein 0.004 0.0746 0.0999
Schistosoma mansoni hypothetical protein 0.0015 0.0169 0.0169
Echinococcus multilocularis snurportin 1 0.031 0.7077 0.7077
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.0075 0.157 0.157
Brugia malayi Bromodomain containing protein 0.0074 0.1564 0.5905
Echinococcus granulosus polycomb protein SCMH1 0.0046 0.09 0.09
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0182 0.4069 0.4069
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0044 0.0044
Echinococcus granulosus fetal alzheimer antigen falz 0.0024 0.0374 0.0374
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0019 0.0258 0.0306
Echinococcus multilocularis lamin dm0 0.0026 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0013 0.0116 0.0104
Echinococcus granulosus ubiquitin specific protease 41 0.0075 0.157 0.157
Plasmodium vivax nicotinate-nucleotide adenylyltransferase, putative 0.0304 0.6923 1
Brugia malayi PHD-finger family protein 0.0026 0.0428 0.1373
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0065 0.1338 0.1338
Loa Loa (eye worm) hypothetical protein 0.0046 0.09 0.1218
Onchocerca volvulus Huntingtin homolog 0.0118 0.259 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0402 0.022
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0029 0.0502 0.0652
Trichomonas vaginalis importin beta-1, putative 0.0024 0.0373 0.0877
Plasmodium falciparum importin beta, putative 0.0029 0.0502 0.037
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0258 0.0636
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0019 0.0256 0.0035
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0258 0.0935
Leishmania major DNA polymerase kappa, putative 0.0019 0.0258 0.0636
Leishmania major DNA polymerase eta, putative 0.0043 0.0834 0.4744
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0149 0.0259
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Mycobacterium ulcerans DNA polymerase IV 0.0019 0.0258 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0402 0.022
Mycobacterium ulcerans acyl-CoA synthetase 0.0025 0.0402 0.022
Echinococcus granulosus dna polymerase kappa 0.0019 0.0258 0.0258
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0065 0.1333 0.1333
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Brugia malayi RNA, U transporter 1 0.0083 0.1755 0.6667
Leishmania major importin beta-1 subunit, putative 0.0024 0.0373 0.1457
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.0075 0.157 0.157
Trypanosoma brucei DNA polymerase eta, putative 0.0043 0.0834 0.4912
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0149 0.015
Schistosoma mansoni zinc finger protein 0.0021 0.0307 0.0307
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0432 0.0552
Schistosoma mansoni hypothetical protein 0.028 0.6373 0.6373
Onchocerca volvulus 0.0031 0.0537 0.0617
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.09 0.09
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0258 0.0636
Brugia malayi mbt repeat family protein 0.0046 0.09 0.3256
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1333 0.1617
Loa Loa (eye worm) hypothetical protein 0.0025 0.0402 0.051
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0025 0.0402 0.022
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.157 1
Echinococcus multilocularis SAM and MBT domain containing protein 0.0046 0.09 0.09
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0025 0.0402 0.022
Schistosoma mansoni cpg binding protein 0.0034 0.0621 0.0621
Echinococcus multilocularis ubiquitin specific protease 41 0.0075 0.157 0.157
Echinococcus granulosus intermediate filament protein 0.0026 0.0432 0.0432
Brugia malayi Importin beta-1 subunit 0.0029 0.0502 0.1668
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0035 0.0637 0.0637
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0432 0.0552
Mycobacterium leprae PROBABLE NICOTINATE-NUCLEOTIDE ADENYLYLTRANSFERASE NADD (DEAMIDO-NAD(+) PYROPHOSPHORYLASE) (DEAMIDO-NAD(+) DIPHOSPHORYLASE) (NIC 0.0304 0.6923 1
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0402 0.1661
Schistosoma mansoni importin beta-1 0.0029 0.0502 0.0502
Leishmania major DNA polymerase eta, putative 0.003 0.0533 0.2598
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Mycobacterium tuberculosis Conserved hypothetical protein 0.0019 0.0258 0.004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0025 0.0402 0.0254
Loa Loa (eye worm) PHD-finger family protein 0.002 0.029 0.0351
Loa Loa (eye worm) hypothetical protein 0.0019 0.0256 0.0301
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0019 0.0258 0.0258
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1333 0.1617
Echinococcus granulosus SAM and MBT domain containing protein 0.0046 0.09 0.09
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0044 0.0044
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0402 0.1269
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0537 0.0702
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0019 0.0258 0.004
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0019 0.0258 0.0258
Toxoplasma gondii histone lysine methyltransferase SET1 0.006 0.123 0.8757
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.09 0.09
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0019 0.0258 0.0258
Echinococcus multilocularis zinc finger protein 0.0021 0.0307 0.0307
Loa Loa (eye worm) hypothetical protein 0.0043 0.083 0.1119
Plasmodium falciparum nicotinamide/nicotinic acid mononucleotide adenylyltransferase 0.0304 0.6923 1
Onchocerca volvulus 0.0046 0.09 0.2276
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.157 1
Echinococcus multilocularis geminin 0.0192 0.4318 0.4318
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.0834 0.2992
Schistosoma mansoni lamin 0.0026 0.0432 0.0432
Trypanosoma cruzi DNA polymerase eta, putative 0.0043 0.0834 0.4744
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.0075 0.157 0.593
Schistosoma mansoni cpg binding protein 0.0031 0.0537 0.0537
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0019 0.0258 0.0636
Echinococcus granulosus cpg binding protein 0.0034 0.0621 0.0621
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Loa Loa (eye worm) hypothetical protein 0.0075 0.157 0.2171
Entamoeba histolytica hypothetical protein 0.0024 0.0373 0.0877
Echinococcus granulosus lamin dm0 0.0026 0.0432 0.0432
Schistosoma mansoni hypothetical protein 0.0192 0.4318 0.4318
Toxoplasma gondii aldehyde dehydrogenase 0.0065 0.1333 1
Brugia malayi CXXC zinc finger family protein 0.0031 0.0537 0.1808
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0373 0.0877
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.09 0.09
Mycobacterium ulcerans aldehyde dehydrogenase 0.0065 0.1333 0.1617
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0402 0.1269
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0258 0.0636
Echinococcus multilocularis dna polymerase kappa 0.0019 0.0258 0.0258
Schistosoma mansoni cpg binding protein 0.0034 0.0621 0.0621
Echinococcus multilocularis musashi 0.0026 0.0432 0.0432
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0046 0.09 0.09
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0026 0.0421 0.0536
Schistosoma mansoni lamin 0.0026 0.0432 0.0432
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0025 0.0402 0.022
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0024 0.0373 0.0877
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.0075 0.157 0.157
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.09 0.09
Brugia malayi mbt repeat family protein 0.0046 0.09 0.3256
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0035 0.0637 0.0637
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0025 0.0402 0.0254
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0025 0.0402 0.022
Echinococcus granulosus dna polymerase eta 0.0043 0.0834 0.0834
Onchocerca volvulus 0.0026 0.0432 0.0136
Trypanosoma brucei DNA polymerase kappa, putative 0.0019 0.0258 0.0935
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.09 0.09
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.0075 0.157 1
Trypanosoma brucei DNA polymerase IV, putative 0.0019 0.0258 0.0935
Schistosoma mansoni aldehyde dehydrogenase 0.0065 0.1333 0.1333
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0065 0.1333 0.1333
Schistosoma mansoni sex comb on midleg homolog 0.0046 0.09 0.09
Loa Loa (eye worm) hypothetical protein 0.0012 0.0105 0.0088
Trypanosoma cruzi DNA polymerase kappa, putative 0.0019 0.0258 0.0636
Loa Loa (eye worm) hypothetical protein 0.0019 0.0256 0.0301
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.09 0.1218
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0225 0.0225
Leishmania major 4-coumarate:coa ligase-like protein 0.0025 0.0402 0.1661
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.0075 0.157 0.157
Echinococcus multilocularis cpg binding protein 0.0034 0.0621 0.0621
Echinococcus granulosus lamin 0.0026 0.0432 0.0432
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0017 0.0225 0.0225
Schistosoma mansoni methyl-cpg binding protein mbd 0.0017 0.0209 0.0209
Brugia malayi AMP-binding enzyme family protein 0.0025 0.0402 0.1269
Schistosoma mansoni terminal deoxycytidyl transferase 0.0019 0.0258 0.0258
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0065 0.1333 0.8309
Trypanosoma brucei ISWI complex protein 0.0015 0.0169 0.032
Loa Loa (eye worm) hypothetical protein 0.0043 0.0834 0.1124
Loa Loa (eye worm) hypothetical protein 0.0019 0.0256 0.0301
Echinococcus granulosus geminin 0.0192 0.4318 0.4318
Mycobacterium tuberculosis Probable nicotinate-nucleotide adenylyltransferase NadD (deamido-NAD(+) pyrophosphorylase) (deamido-NAD(+) diphosphorylase) (nic 0.0304 0.6923 1
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0019 0.0256 0.5
Schistosoma mansoni DNA polymerase eta 0.0043 0.0834 0.0834

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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