Detailed information for compound 622093

Basic information

Technical information
  • TDR Targets ID: 622093
  • Name: ethyl 2-[[4-(diethylsulfamoyl)benzoyl]amino]- 6-methylthieno[5,4-d][1,3]thiazole-5-carboxyl ate
  • MW: 481.609 | Formula: C20H23N3O5S3
  • H donors: 1 H acceptors: 5 LogP: 4.36 Rotable bonds: 10
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)c1sc2c(c1C)sc(n2)NC(=O)c1ccc(cc1)S(=O)(=O)N(CC)CC
  • InChi: 1S/C20H23N3O5S3/c1-5-23(6-2)31(26,27)14-10-8-13(9-11-14)17(24)21-20-22-18-15(30-20)12(4)16(29-18)19(25)28-7-3/h8-11H,5-7H2,1-4H3,(H,21,22,24)
  • InChiKey: HAMDQWYXYZDENO-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • ethyl 2-[[4-(diethylsulfamoyl)benzoyl]amino]-6-methyl-thieno[5,4-d]thiazole-5-carboxylate
  • 2-[[[4-(diethylsulfamoyl)phenyl]-oxomethyl]amino]-6-methyl-5-thieno[5,4-d]thiazolecarboxylic acid ethyl ester
  • 2-[[4-(diethylsulfamoyl)benzoyl]amino]-6-methyl-thieno[5,4-d]thiazole-5-carboxylic acid ethyl ester
  • ethyl 2-[[4-(diethylsulfamoyl)phenyl]carbonylamino]-6-methyl-thieno[5,4-d][1,3]thiazole-5-carboxylate
  • Oprea1_309417

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0015 0.0034
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0095 0.0538 0.0534
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0089 0.0066
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0018 0.0071 0.1314
Mycobacterium tuberculosis Probable hydrolase 0.0037 0.0184 0.0856
Echinococcus granulosus phosphatidylinositol 4 phosphate 3 kinase C2 0.0018 0.0071 0.008
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0289 0.2044
Entamoeba histolytica Phosphatidylinositol 3- and 4-kinase family 0.0054 0.0286 0.4601
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.019 0.0427
Entamoeba histolytica hypothetical protein 0.0037 0.0184 0.2423
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.002 0.0071
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0037 0.0184 0.0856
Brugia malayi beta-lactamase family protein 0.0037 0.0184 0.1274
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0095 0.0538 0.1609
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0037 0.0184 0.1274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0016 0.0058 0.0054
Mycobacterium ulcerans lipase LipD 0.0037 0.0184 0.305
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0089 0.0578
Schistosoma mansoni survival motor neuron protein 0.0047 0.0248 0.0291
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Schistosoma mansoni smad1 5 8 and 0.0008 0.001 0.0007
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0095 0.0538 0.1673
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0184 0.3422
Echinococcus multilocularis DNA dependent protein kinase catalytic subunit 0.1363 0.8266 0.8265
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0071 0.1314
Echinococcus multilocularis phosphatidylinositol 4 phosphate 3 kinase C2 0.0018 0.0071 0.0067
Onchocerca volvulus 0.0021 0.0089 0.1814
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0401 0.2862
Echinococcus granulosus phosphatidylinositol 3 kinase catalytic subunit 0.0018 0.0071 0.008
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0051 0.0271 0.1907
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0136 0.0922
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.019 0.353
Trichomonas vaginalis esterase, putative 0.0037 0.0184 0.3422
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.002 0.0016
Onchocerca volvulus 0.0037 0.0184 0.431
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0401 1
Mycobacterium tuberculosis Conserved protein 0.0037 0.0184 0.0856
Loa Loa (eye worm) steroid hormone receptor 0.001 0.002 0.0071
Echinococcus granulosus lamin 0.0054 0.0289 0.034
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.002 0.0071
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0071
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0245 0.0241
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0236 0.1395 1
Loa Loa (eye worm) inositol-1 0.0038 0.019 0.1317
Loa Loa (eye worm) hypothetical protein 0.0021 0.0089 0.0578
Brugia malayi MH2 domain containing protein 0.0122 0.0705 0.5086
Loa Loa (eye worm) hypothetical protein 0.0037 0.0184 0.1274
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.0089 0.0138
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Loa Loa (eye worm) hypothetical protein 0.0072 0.0401 0.2862
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0095 0.0538 1
Mycobacterium ulcerans esterase/lipase LipP 0.0037 0.0184 0.305
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0072 0.0401 1
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.034 0.04
Schistosoma mansoni inositol monophosphatase 0.0038 0.019 0.0222
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0051 0.0271 0.1907
Giardia lamblia GTOR 0.0095 0.0538 1
Entamoeba histolytica hypothetical protein 0.0037 0.0184 0.2423
Schistosoma mansoni ataxia telangiectasia mutated (atm) 0.0054 0.0286 0.0336
Onchocerca volvulus 0.0018 0.0071 0.1333
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0072 0.0401 0.2493
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.075
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.0089 0.0138
Loa Loa (eye worm) phosphatidylinositol 4-kinase type 3 alpha isoform 1 0.0018 0.0071 0.0443
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0072 0.0401 0.2493
Trypanosoma cruzi phosphatidylinositol 3-kinase, putative 0.0054 0.0286 0.077
Loa Loa (eye worm) phosphatidylinositol 3 0.0095 0.0538 0.3866
Echinococcus granulosus phosphatidylinositol 45 bisphosphate 3 kinase 0.0018 0.0071 0.008
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0401 0.2862
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0289 0.2044
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0054 0.0289 0.6421
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0071 0.0002
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0037 0.0184 0.018
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0245 0.0287
Schistosoma mansoni smad1 5 8 and 0.0008 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.0232 0.1376 1
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0016 0.0058 0.0054
Schistosoma mansoni intermediate filament proteins 0.0054 0.0289 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Echinococcus multilocularis geminin 0.0518 0.3115 0.3113
Echinococcus multilocularis GPCR, family 2 0.0016 0.0058 0.0054
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0286 0.5311
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0089 0.0138
Brugia malayi intermediate filament protein 0.0054 0.0289 0.2044
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0072 0.0401 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0289 0.2044
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0016 0.0058 0.0349
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.002 0.0019
Loa Loa (eye worm) hypothetical protein 0.0153 0.0892 0.6457
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0401 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.0089 0.0837
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0095 0.0538 0.1673
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0071 0.1314
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0038 0.019 0.5
Echinococcus multilocularis lamin 0.0054 0.0289 0.0285
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0072 0.0401 1
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0071 0.008
Brugia malayi follicle stimulating hormone receptor 0.0228 0.1347 0.9787
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0071 0.0443
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.0089 0.0392
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.0089 0.0138
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.002 0.0071
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0037 0.0184 0.0856
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0035 0.0174 0.0371
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0016 0.0058 0.0064
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0018 0.0071 0.008
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0095 0.0538 0.3866
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0136 0.0922
Loa Loa (eye worm) hypothetical protein 0.006 0.0323 0.2291
Onchocerca volvulus 0.0029 0.0139 0.3117
Schistosoma mansoni inositol monophosphatase 0.0038 0.019 0.0222
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0072 0.0401 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0401 1
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0095 0.0538 1
Schistosoma mansoni smad 0.0008 0.001 0.0007
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0184 0.3422
Brugia malayi CXXC zinc finger family protein 0.0029 0.0139 0.0941
Echinococcus multilocularis smad 0.0008 0.001 0.0006
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0095 0.0538 0.1673
Schistosoma mansoni coup transcription factor 0.001 0.002 0.0019
Echinococcus multilocularis cpg binding protein 0.0031 0.0149 0.0145
Echinococcus multilocularis phosphatidylinositol 4,5 bisphosphate 3 kinase 0.0018 0.0071 0.0067
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0089 0.0578
Echinococcus multilocularis FTZ F1 alpha 0.001 0.002 0.0016
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0018 0.0071 0.1314
Loa Loa (eye worm) hypothetical protein 0.0025 0.0113 0.075
Echinococcus granulosus lamin dm0 0.0054 0.0289 0.034
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.002 0.0016
Echinococcus multilocularis phosphatidylinositol 4 kinase alpha 0.0018 0.0071 0.0067
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0071 0.0443
Mycobacterium tuberculosis Probable lipase LipE 0.0037 0.0184 0.0856
Loa Loa (eye worm) hypothetical protein 0.0054 0.0289 0.2044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Echinococcus granulosus smad 0.0008 0.001 0.0007
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0271 0.1514
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Brugia malayi hypothetical protein 0.0037 0.0184 0.1273
Trypanosoma brucei phosphatidylinositol kinase related protein, putative 0.0054 0.0286 0.4601
Schistosoma mansoni cpg binding protein 0.0031 0.0149 0.0173
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0071
Echinococcus multilocularis microtubule associated protein 2 0.1385 0.8401 0.84
Echinococcus granulosus FTZ F1 alpha 0.001 0.002 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0286 0.5311
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0071 0.0443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0286 0.5311
Schistosoma mansoni hypothetical protein 0.0419 0.2513 0.2988
Loa Loa (eye worm) hypothetical protein 0.0026 0.0119 0.0794
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0184 0.1274
Loa Loa (eye worm) hypothetical protein 0.0072 0.0401 0.2862
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.0089 0.0578
Schistosoma mansoni hypothetical protein 0.0016 0.0058 0.0064
Schistosoma mansoni hypothetical protein 0.0016 0.0058 0.0064
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.002 0.0016
Toxoplasma gondii FATC domain-containing protein 0.0054 0.0286 0.4601
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.0089 0.0138
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.002 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0184 0.1274
Brugia malayi nuclear receptor NHR-88 0.001 0.002 0.0071
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.0089 0.0578
Echinococcus granulosus Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0071 0.008
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.0089 0.0085
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.0089 0.0837
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0071 0.0443
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.019 0.0427
Mycobacterium ulcerans acyl-CoA synthetase 0.0072 0.0401 1
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.002 0.0071
Loa Loa (eye worm) hypothetical protein 0.0041 0.0212 0.1476
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0184 0.3422
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.002 0.0071
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0018 0.0071 0.1314
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0119 0.0115
Onchocerca volvulus 0.0018 0.0071 0.1333
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.002 0.0019
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.0089 0.0138
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0071
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0071
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.0089 0.0392
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0184 0.0406
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0034 0.0166 0.0718
Echinococcus multilocularis musashi 0.0054 0.0289 0.0285
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0018 0.0071 0.1314
Schistosoma mansoni Smad4 0.0008 0.001 0.0007
Schistosoma mansoni hypothetical protein 0.0047 0.0248 0.0291
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0095 0.0538 0.1609
Brugia malayi FAT domain containing protein 0.0041 0.0212 0.1476
Schistosoma mansoni thyroid hormone receptor 0.001 0.002 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0089 0.0578
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0245 0.0287
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0018 0.0071 0.008
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.0089 0.0554
Brugia malayi latrophilin 2 splice variant baaae 0.0035 0.0172 0.1186
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0401 0.7066
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit gamma, putative 0.0018 0.0071 0.1314
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0286 0.5311
Echinococcus granulosus cpg binding protein 0.0031 0.0149 0.0173
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.002 0.0071
Echinococcus granulosus geminin 0.0518 0.3115 0.3706
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0018 0.0071 0.008
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.002 0.0019
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.001 0.0007
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0089 0.0138
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.0089 0.0138
Schistosoma mansoni hypothetical protein 0.0518 0.3115 0.3706
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0071 0.0443
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0071 0.0067
Brugia malayi beta-lactamase family protein 0.0037 0.0184 0.1274
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.001 0.0007
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0139 0.0941
Echinococcus granulosus dnaJ subfamily B 0.0419 0.2513 0.2988
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.002 0.0071
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.006 0.0323 0.5399
Toxoplasma gondii propionate-CoA ligase 0.0021 0.0089 0.0392
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.002 0.0071
Entamoeba histolytica hypothetical protein 0.0054 0.0286 0.4601
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.002 0.0019
Echinococcus multilocularis lamin dm0 0.0054 0.0289 0.0285
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0051 0.0271 0.1907
Onchocerca volvulus 0.0037 0.0184 0.431
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0071 0.0443
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0038 0.019 0.2551
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.002 0.0016
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0705 0.5086
Trichomonas vaginalis phosphatidylinositol 4-kinase, putative 0.0018 0.0071 0.1314
Schistosoma mansoni nuclear hormone receptor 0.001 0.002 0.0019
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0095 0.0538 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0037 0.0184 0.0214
Echinococcus granulosus beta LACTamase domain containing family member 0.0037 0.0184 0.0215
Echinococcus granulosus GPCR family 2 0.0016 0.0058 0.0064
Onchocerca volvulus 0.0021 0.0089 0.1814
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0047 0.0245 0.1719
Brugia malayi hypothetical protein 0.0232 0.1376 1
Schistosoma mansoni transcription factor LCR-F1 0.0037 0.0184 0.0214
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.0089 0.0138
Toxoplasma gondii target of rapamycin (TOR), putative 0.0095 0.0538 1
Schistosoma mansoni phosphatidylinositol 4-kinase 0.0018 0.0071 0.008
Schistosoma mansoni smad1 5 8 and 0.0008 0.001 0.0007
Onchocerca volvulus 0.0054 0.0289 0.7069
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Echinococcus granulosus intermediate filament protein 0.0054 0.0289 0.034
Brugia malayi AMP-binding enzyme family protein 0.0072 0.0401 0.2862
Loa Loa (eye worm) oxidoreductase 0.0021 0.0089 0.0578
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.002 0.0071
Schistosoma mansoni fkbp-rapamycin associated protein 0.0054 0.0286 0.0336
Onchocerca volvulus 0.0054 0.0289 0.7069
Echinococcus multilocularis dnaJ subfamily B 0.0419 0.2513 0.251
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0089 0.0063
Brugia malayi Steroid receptor seven-up type 2 0.001 0.002 0.0071
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0071
Brugia malayi phosphatidylinositol 4-kinase, catalytic, alpha polypeptide 0.0018 0.0071 0.0443
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0095 0.0538 0.0636
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.002 0.0071
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0271 0.1514
Entamoeba histolytica acyl-coA synthetase, putative 0.0072 0.0401 0.7066
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0089 0.0066
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0015 0.0011
Trichomonas vaginalis phopsphatidylinositol 3-kinase, drosophila, putative 0.0018 0.0071 0.1314
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.1376 0.1634
Mycobacterium ulcerans beta-lactamase 0.0037 0.0184 0.305
Toxoplasma gondii ABC1 family protein 0.0037 0.0184 0.2427
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0089 0.0138
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0038 0.019 0.353
Echinococcus granulosus microtubule associated protein 2 0.1385 0.8401 1
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0089 0.0392
Mycobacterium ulcerans hypothetical protein 0.0037 0.0184 0.305
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0016 0.0058 0.0064
Entamoeba histolytica hypothetical protein 0.0037 0.0184 0.2423
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.002 0.0019
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0089 0.0578
Echinococcus granulosus phosphatidylinositol 4 kinase alpha 0.0018 0.0071 0.008
Toxoplasma gondii non-specific serine/threonine protein kinase 0.006 0.0323 0.5399
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.1376 0.1372
Echinococcus granulosus serine protein kinase ATM 0.0054 0.0286 0.0336
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0071 0.0443
Schistosoma mansoni thyroid hormone receptor 0.001 0.002 0.0019
Schistosoma mansoni phosphatidylinositol 4-kinase type-II 0.0018 0.0071 0.008
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.002 0.0016
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0015 0.0013
Schistosoma mansoni lamin 0.0054 0.0289 0.034
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0071 0.0443
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0095 0.0538 0.0636
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0038 0.019 0.2551
Echinococcus multilocularis muscleblind protein 1 0.0153 0.0892 0.0888
Loa Loa (eye worm) hypothetical protein 0.0054 0.0289 0.2044
Echinococcus multilocularis Smad4 0.0008 0.001 0.0006
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.001 0.0006
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.0172 0.1186
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Loa Loa (eye worm) hypothetical protein 0.0016 0.0058 0.0349
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.0184 0.0406
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Echinococcus granulosus serine:threonine protein kinase SMG1 0.0054 0.0286 0.0336
Mycobacterium tuberculosis Probable esterase LipL 0.0037 0.0184 0.0856
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0289 0.2044
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0245 0.0287
Echinococcus multilocularis muscleblind protein 0.0153 0.0892 0.0888
Leishmania major phosphatidylinositol 3-kinase, putative 0.0095 0.0538 0.1609
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0271 0.1514
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0095 0.0538 0.3866
Trichomonas vaginalis penicillin-binding protein, putative 0.0037 0.0184 0.3422
Onchocerca volvulus 0.0072 0.0401 1
Loa Loa (eye worm) hypothetical protein 0.0054 0.0289 0.2044
Echinococcus granulosus inositol monophosphatase 1 0.0038 0.019 0.0222
Loa Loa (eye worm) hypothetical protein 0.0037 0.0184 0.1274
Onchocerca volvulus 0.0021 0.0089 0.1814
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0041 0.0212 0.0247
Brugia malayi Inositol-1 0.0038 0.019 0.1317
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0174 0.3242
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0228 0.1347 0.9787
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0089 0.1654
Loa Loa (eye worm) phosphatidylinositol kinase 0.0018 0.0071 0.0443
Mycobacterium tuberculosis Conserved protein 0.0037 0.0184 0.0856
Loa Loa (eye worm) hypothetical protein 0.0054 0.0286 0.2018
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.002 0.0019
Schistosoma mansoni hypothetical protein 0.0035 0.0172 0.02
Echinococcus multilocularis 0.0018 0.0071 0.0067
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.002 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.002 0.0071
Trichomonas vaginalis conserved hypothetical protein 0.006 0.0323 0.6004
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0037 0.0184 0.1274
Loa Loa (eye worm) hypothetical protein 0.0037 0.0184 0.1274
Schistosoma mansoni hypothetical protein 0.0016 0.0058 0.0064
Loa Loa (eye worm) hypothetical protein 0.0153 0.0892 0.6457
Loa Loa (eye worm) hypothetical protein 0.0054 0.0289 0.2044
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Plasmodium falciparum acyl-CoA synthetase 0.0054 0.0289 1
Echinococcus granulosus DNA dependent protein kinase catalytic subunit 0.1363 0.8266 0.984
Plasmodium vivax acyl-CoA synthetase, putative 0.0054 0.0289 1
Echinococcus multilocularis serine protein kinase ATM 0.0054 0.0286 0.0282
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.002 0.0019
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.0089 0.0392
Trypanosoma cruzi target of rapamycin kinase 3 0.0095 0.0538 0.1673
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0286 0.2018
Loa Loa (eye worm) hypothetical protein 0.0051 0.0271 0.1907
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0286 0.5311
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0212 0.3934
Schistosoma mansoni cpg binding protein 0.0031 0.0149 0.0173
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0095 0.0538 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0184 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.002 0.0071
Trichomonas vaginalis inositol monophosphatase, putative 0.0038 0.019 0.353
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0054 0.0289 0.165
Echinococcus multilocularis Phosphatidylinositol 4 kinase type 2 beta 0.0018 0.0071 0.0067
Loa Loa (eye worm) hypothetical protein 0.0035 0.0174 0.1203
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.0089 0.0101
Echinococcus granulosus Smad4 0.0008 0.001 0.0007
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.002 0.0071
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.002 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.0089 0.0063
Trypanosoma cruzi phosphatidylinositol kinase related protein, putative 0.0054 0.0286 0.077
Loa Loa (eye worm) beta-lactamase 0.0037 0.0184 0.1274
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0286 0.5311
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.019 0.2551
Schistosoma mansoni hypothetical protein 0.0037 0.0184 0.0214
Schistosoma mansoni hypothetical protein 0.0518 0.3115 0.3706
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.002 0.0019
Mycobacterium leprae Probable lipase LipE 0.0037 0.0184 0.3435
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0286 0.5311
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Brugia malayi ecdysteroid receptor 0.001 0.002 0.0071
Schistosoma mansoni phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha PI3K 0.0018 0.0071 0.008
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.002 0.0071
Loa Loa (eye worm) latrophilin receptor protein 2 0.0016 0.0058 0.0349
Brugia malayi Latrophilin receptor protein 2 0.0016 0.0058 0.0349
Brugia malayi beta-lactamase 0.0037 0.0184 0.1274
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0071 0.0443
Loa Loa (eye worm) hypothetical protein 0.0018 0.0071 0.0443
Schistosoma mansoni microtubule-associated protein tau 0.1385 0.8401 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0089 0.0578
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0401 0.1137
Schistosoma mansoni hypothetical protein 0.0016 0.0058 0.0064
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0018 0.0071 0.1314
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0095 0.0538 0.0636
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0018 0.0071 0.1314
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.002 0.0016
Trichomonas vaginalis PIKK family atypical protein kinase 0.006 0.0323 0.6004
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0037 0.0184 0.0215
Trichomonas vaginalis phosphatidylinositol 3-kinase catalytic subunit alpha, beta, delta, putative 0.0018 0.0071 0.1314
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0018 0.0071 0.0443
Loa Loa (eye worm) hypothetical protein 0.0037 0.0184 0.1274
Brugia malayi steroid hormone receptor 0.001 0.002 0.0071
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0089 0.0063
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0054 0.0286 0.2018
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0054 0.0289 0.5
Mycobacterium leprae conserved hypothetical protein 0.0037 0.0184 0.3435
Brugia malayi nuclear hormone receptor 0.001 0.002 0.0071
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.002 0.0071
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.002 0.0019
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.0089 0.0554
Echinococcus multilocularis beta LACTamase domain containing family member 0.0037 0.0184 0.018
Schistosoma mansoni cpg binding protein 0.0029 0.0139 0.016
Trichomonas vaginalis conserved hypothetical protein 0.0035 0.0174 0.3242
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.002 0.0071
Schistosoma mansoni hypothetical protein 0.0018 0.0071 0.008
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0037 0.0184 0.305
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.002 0.0019
Entamoeba histolytica protein kinase rad3, putative 0.0054 0.0286 0.4601
Trichomonas vaginalis D-aminoacylase, putative 0.0037 0.0184 0.3422
Toxoplasma gondii histone lysine methyltransferase SET1 0.0056 0.0299 0.4885
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0095 0.0538 0.0534
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.002 0.0019
Schistosoma mansoni lamin 0.0054 0.0289 0.034
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.0089 0.0138
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.0089 0.1654
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0072 0.0401 1
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0095 0.0538 0.1609
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0705 0.5086
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.0089 0.0392
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0095 0.0538 0.0636
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0095 0.0538 1
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.0089 0.0101
Brugia malayi Muscleblind-like protein 0.0153 0.0892 0.6457
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0047 0.0245 0.1719
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.0089 0.0066
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Plasmodium vivax hypothetical protein, conserved 0.0037 0.0184 0.5189
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0047 0.0245 0.0241
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.002 0.0071
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.002 0.0019
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.0089 0.0578
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0051 0.0271 0.1514
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0095 0.0538 0.1609
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0047 0.0245 0.0287
Loa Loa (eye worm) hypothetical protein 0.0053 0.0283 0.2
Loa Loa (eye worm) hypothetical protein 0.0072 0.0401 0.2862
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0401 0.1137
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0248 0.1744
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.002 0.0071
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0034 0.0166 0.2879
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0095 0.0538 1
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.0089 0.0066
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0018 0.0071 0.1314
Leishmania major hypothetical protein, conserved 0.0495 0.2976 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0018 0.0071 0.0443
Trypanosoma brucei hypothetical protein, conserved 0.0037 0.0184 0.2427
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.002 0.0019
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.0089 0.0554
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0014 0.0029
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.001 0.0007
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0071
Echinococcus granulosus PIK kinase FAT and Armadillo domain containing protein 0.0041 0.0212 0.0247
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.002 0.0019
Echinococcus granulosus phosphatidylinositol 4 kinase beta 0.0018 0.0071 0.008
Entamoeba histolytica hypothetical protein 0.0037 0.0184 0.2423
Loa Loa (eye worm) hypothetical protein 0.0018 0.0071 0.0443
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Loa Loa (eye worm) phosphatidylinositol 3 0.0095 0.0538 0.3866
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0038 0.019 0.3236
Trichomonas vaginalis PIKK family atypical protein kinase 0.0018 0.0071 0.1314
Leishmania major 4-coumarate:coa ligase-like protein 0.0072 0.0401 0.1137
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0095 0.0538 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0047 0.0245 0.0287
Onchocerca volvulus 0.0037 0.0184 0.431
Echinococcus multilocularis inositol monophosphatase 1 0.0038 0.019 0.0186
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0095 0.0538 0.1673
Trichomonas vaginalis PIKK family atypical protein kinase 0.0054 0.0286 0.5311
Echinococcus granulosus muscleblind protein 0.0153 0.0892 0.1058
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.002 0.0071
Schistosoma mansoni phosphatidylinositol 3-kinase class 0.0018 0.0071 0.008
Loa Loa (eye worm) hypothetical protein 0.001 0.002 0.0071
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0119 0.0137
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.002 0.0071
Onchocerca volvulus 0.0047 0.0248 0.5993
Brugia malayi AMP-binding enzyme family protein 0.0021 0.0089 0.0578
Loa Loa (eye worm) hypothetical protein 0.0054 0.0289 0.2044
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.001 0.0006
Echinococcus multilocularis serine:threonine protein kinase SMG1 0.0054 0.0286 0.0282
Leishmania major hypothetical protein, conserved 0.0037 0.0184 0.039
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0038 0.019 0.041
Entamoeba histolytica acyl-CoA synthetase, putative 0.0072 0.0401 0.7066
Mycobacterium tuberculosis Conserved protein 0.0037 0.0184 0.0856
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.002 0.0019
Echinococcus multilocularis PIK kinase, FAT and Armadillo domain containing protein 0.0041 0.0212 0.0208
Mycobacterium tuberculosis Probable lipase LipD 0.0037 0.0184 0.0856
Mycobacterium ulcerans hypothetical protein 0.0072 0.0401 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.002 0.0071
Onchocerca volvulus 0.0021 0.0089 0.1814
Trichomonas vaginalis PIKK family atypical protein kinase 0.0095 0.0538 1
Echinococcus multilocularis Zinc finger, PHD finger 0.0018 0.0071 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0477 0.2865 1
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0037 0.0184 0.0856
Trichomonas vaginalis phosphatidylinositol 3-kinase class, putative 0.0018 0.0071 0.1314
Trichomonas vaginalis phosphatidylinositol kinase, putative 0.0018 0.0071 0.1314

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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