Detailed information for compound 646287

Basic information

Technical information
  • TDR Targets ID: 646287
  • Name: [[amino-(3-methylphenyl)methylidene]amino] 3- iodobenzoate
  • MW: 380.18 | Formula: C15H13IN2O2
  • H donors: 1 H acceptors: 1 LogP: 4.05 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: Cc1cccc(c1)C(=N)NOC(=O)c1cccc(c1)I
  • InChi: 1S/C15H13IN2O2/c1-10-4-2-5-11(8-10)14(17)18-20-15(19)12-6-3-7-13(16)9-12/h2-9H,1H3,(H2,17,18)
  • InChiKey: NDEMSLMIHSHYRD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [[amino-(3-methylphenyl)methylene]amino] 3-iodobenzoate
  • 3-iodobenzoic acid [[amino-(3-methylphenyl)methylene]amino] ester
  • BIM-0002924.P001
  • CBMicro_003173
  • STK041538

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0025 0.0342
Schistosoma mansoni hypothetical protein 0.065 0.2605 0.4816
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0706 0.1305
Loa Loa (eye worm) hypothetical protein 0.0053 0.0159 0.0415
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0159 0.1613
Toxoplasma gondii exonuclease III APE 0.002 0.0025 0.0159
Brugia malayi F/Y-rich N-terminus family protein 0.0029 0.0061 0.0158
Onchocerca volvulus 0.0189 0.0716 1
Trichomonas vaginalis sensor histidine kinase, putative 0.0053 0.0159 0.1611
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0081 0.0164
Brugia malayi Importin beta-1 subunit 0.0061 0.0193 0.0504
Trichomonas vaginalis helicase, putative 0.0021 0.0031 0.0304
Loa Loa (eye worm) hypothetical protein 0.0047 0.0138 0.036
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) 0.0112 0.0402 0.0823
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.008 0.027 0.0497
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0045 0.0127 0.7839
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0189 0.0716 0.1324
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.1878
Echinococcus multilocularis dnaJ subfamily B 0.1334 0.5407 0.5407
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.1878
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0108 0.0386 0.1011
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0012 0.003
Leishmania major cathepsin L-like protease 0.0017 0.0012 0.0028
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0706 0.1305
Plasmodium vivax vivapain-2 0.0017 0.0012 0.0152
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0706 0.0706
Mycobacterium tuberculosis Two component sensor histidine kinase DosT 0.0053 0.0159 0.0324
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0029 0.0075
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0025 0.0374
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0138 0.036
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0189 0.0716 1
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0982 1
Brugia malayi Cathepsin L-like precursor 0.0017 0.0012 0.0028
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0231
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Mycobacterium ulcerans two component sensor histidine kinase DevS 0.0053 0.0159 0.2209
Brugia malayi heat shock protein 90 0.0053 0.0159 0.0415
Loa Loa (eye worm) hypothetical protein 0.0047 0.0138 0.036
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0012 0.0011
Schistosoma mansoni pyruvate dehydrogenase 0.0892 0.3596 0.6651
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0012 0.015
Trypanosoma cruzi heat shock protein 90, putative 0.0053 0.0159 0.0415
Echinococcus granulosus dna polymerase eta 0.002 0.0025 0.0045
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0025 0.021
Schistosoma mansoni cpg binding protein 0.0094 0.0327 0.0604
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Onchocerca volvulus Glucosylceramidase homolog 0.0166 0.0625 0.8724
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0023 0.0039 0.0038
Trichomonas vaginalis penicillin-binding protein, putative 0.0189 0.0716 0.7292
Echinococcus granulosus Niemann Pick C1 protein 0.0282 0.1097 0.2027
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0252 0.0974 0.2554
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0012 0.0028
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0023 0.0039 0.0071
Entamoeba histolytica hypothetical protein 0.0049 0.0146 0.1935
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0047 0.0121
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0025 0.025
Mycobacterium ulcerans putative regultory protein 0.0053 0.0159 0.2209
Trypanosoma brucei heat shock protein, putative 0.0053 0.0159 0.0417
Echinococcus granulosus carbonic anhydrase 0.0108 0.0386 0.0713
Schistosoma mansoni heat shock protein 0.0053 0.0159 0.0292
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0138 0.036
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0146 0.1478
Trypanosoma brucei developmentally regulated phosphoprotein 0.0944 0.3811 1
Brugia malayi RNA recognition motif domain containing protein 0.0124 0.0452 0.1183
Toxoplasma gondii cathepsin CPL 0.0017 0.0012 0.0072
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0127 0.0332
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0231
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Echinococcus granulosus dnaJ subfamily B 0.1334 0.5407 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Leishmania major carbonic anhydrase-like protein 0.0199 0.076 0.1994
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0025 0.0064
Plasmodium falciparum acyl-CoA synthetase 0.0035 0.0089 0.1372
Mycobacterium leprae Probable two component sensor kinase MprB 0.0053 0.0159 0.2209
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0186 0.0706 0.0706
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Mycobacterium ulcerans esterase/lipase LipP 0.0189 0.0716 1
Echinococcus granulosus survival motor neuron protein 1 0.0234 0.0903 0.1668
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0029 0.0053
Trichomonas vaginalis mismatch repair protein Mlh1C (mutL homolog) 0.0053 0.0159 0.1611
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0452 0.0834
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0012 0.015
Toxoplasma gondii HEAT repeat-containing protein 0.0061 0.0193 0.1273
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0053 0.0159 0.1047
Plasmodium vivax heat shock protein 86, putative 0.0053 0.0159 0.2209
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0202 0.0372
Echinococcus multilocularis dna polymerase kappa 0.002 0.0025 0.0025
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Trypanosoma cruzi importin beta-1 subunit, putative 0.0049 0.0146 0.0381
Brugia malayi beta-lactamase family protein 0.0189 0.0716 0.1878
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0138 0.036
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Chlamydia trachomatis two component regulatory system sensor histidine kinase 0.0053 0.0159 0.2332
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0189 0.0716 0.1324
Wolbachia endosymbiont of Brugia malayi signal transduction histidine kinase and receiver 0.0053 0.0159 0.2332
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0047 0.0138 0.1918
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0982 1
Trypanosoma cruzi Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0053 0.0159 0.0415
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0047 0.0717
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Schistosoma mansoni endoplasmin 0.0053 0.0159 0.0292
Schistosoma mansoni hypothetical protein 0.0082 0.0278 0.0512
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0171 0.0643 1
Brugia malayi Endoplasmin precursor 0.0053 0.0159 0.0415
Giardia lamblia Kinase, CMGC MAPK 0.0053 0.0159 1
Schistosoma mansoni transcription factor LCR-F1 0.0144 0.0533 0.0984
Entamoeba histolytica cysteine protease, putative 0.0017 0.0012 0.0145
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.008 0.027 0.0269
Loa Loa (eye worm) ctsf protein 0.0017 0.0012 0.0028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0029 0.0075
Onchocerca volvulus 0.0017 0.0012 0.0152
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0025 0.0066
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0199 0.076 0.1994
Trichomonas vaginalis D-aminoacylase, putative 0.0189 0.0716 0.7292
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0047 0.0123
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0025 0.0064
Trypanosoma cruzi heat shock protein 85, putative 0.0053 0.0159 0.0415
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0025 0.0245
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0053 0.0159 0.1047
Schistosoma mansoni survival motor neuron protein 0.0048 0.0139 0.0256
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0025 0.0063
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0013 0.0022
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0124 0.0452 0.1183
Echinococcus granulosus mixed lineage leukemia protein mll 0.0023 0.0039 0.0071
Plasmodium falciparum carbonic anhydrase 0.0108 0.0386 0.5995
Trypanosoma brucei unspecified product 0.002 0.0025 0.0066
Echinococcus multilocularis importin subunit beta 1 0.0061 0.0193 0.0192
Mycobacterium tuberculosis Two component sensor kinase [second part] 0.0053 0.0159 0.0324
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0053 0.0159 0.0415
Mycobacterium tuberculosis Possible two component sensor kinase TcrY 0.0053 0.0159 0.0324
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.044 0.6134
Mycobacterium tuberculosis Probable esterase LipL 0.0189 0.0716 0.1467
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0029 0.0075
Toxoplasma gondii hypothetical protein 0.0108 0.0386 0.2551
Schistosoma mansoni hypothetical protein 0.0082 0.0278 0.0512
Entamoeba histolytica hypothetical protein 0.0144 0.0533 0.7093
Trypanosoma brucei pyruvate dehydrogenase (lipoamide) kinase, putative 0.033 0.1296 0.34
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0706 0.1305
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0108 0.0386 0.1011
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0025 0.09
Leishmania major DNA polymerase kappa, putative 0.002 0.0025 0.0064
Mycobacterium ulcerans sensor kinase from two component regulatory system 0.0053 0.0159 0.2209
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0047 0.0138 0.0281
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0013 0.0012
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0944 0.3811 0.3811
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0138 0.036
Trypanosoma brucei hypothetical protein, conserved 0.0189 0.0716 0.188
Echinococcus multilocularis carbonic anhydrase II 0.0199 0.076 0.076
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0625 0.6361
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0108 0.0386 0.1011
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0075
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0013 0.0012
Brugia malayi steroid hormone receptor 0.0021 0.0029 0.0075
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.065 0.2605 0.6833
Echinococcus granulosus microtubule associated protein 2 0.0668 0.268 0.4955
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Brugia malayi hypothetical protein 0.0144 0.0533 0.1396
Trichomonas vaginalis ran, putative 0.0045 0.0127 0.1288
Plasmodium vivax vivapain-2 0.0017 0.0012 0.0152
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0053 0.0159 0.0415
Echinococcus multilocularis mitogen activated protein kinase 3 0.0053 0.0159 0.0158
Trichomonas vaginalis penicillin-binding protein, putative 0.0189 0.0716 0.7292
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0049 0.0146 0.1478
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0982 1
Chlamydia trachomatis ATP-dependent Clp protease proteolytic subunit 0.0171 0.0643 1
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0662 0.6735
Brugia malayi Latrophilin receptor protein 2 0.008 0.027 0.0706
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0171 0.0643 0.4255
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Schistosoma mansoni pyruvate dehydrogenase 0.0944 0.3811 0.7049
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0014 0.0001 0.0002
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0047 0.0138 0.1918
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0159 0.1611
Echinococcus granulosus geminin 0.0513 0.2043 0.3778
Trypanosoma cruzi heat shock protein 90, putative 0.0053 0.0159 0.0415
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0075
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0012 0.015
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0012 0.0071
Trichomonas vaginalis endoplasmin, putative 0.0053 0.0159 0.1611
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.044 0.09
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0012 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Echinococcus multilocularis carbonic anhydrase 0.0108 0.0386 0.0385
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.044 0.09
Entamoeba histolytica DNA topoisomerase II, putative 0.0053 0.0159 0.2108
Schistosoma mansoni hypothetical protein 0.0048 0.0139 0.0256
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0025 0.0066
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) 0.0171 0.0643 0.898
Mycobacterium leprae PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 0.0053 0.0159 0.2209
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0029 0.0053
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0014 0.0001 0.0002
Onchocerca volvulus 0.0047 0.0138 0.1918
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.039 0.0798
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0053 0.0159 0.1048
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0029 0.0029
Trypanosoma brucei Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative 0.0053 0.0159 0.0417
Trypanosoma brucei trypanothione reductase 0.0048 0.0139 0.0366
Leishmania major mitochondrial DNA topoisomerase II 0.0053 0.0159 0.0415
Loa Loa (eye worm) endoplasmin 0.0053 0.0159 0.0415
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0012 0.0152
Plasmodium vivax endoplasmin, putative 0.0053 0.0159 0.2209
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0029 0.0053
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0012 0.002
Schistosoma mansoni carbonic anhydrase-related 0.0108 0.0386 0.0713
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.044 0.09
Mycobacterium tuberculosis Probable lipase LipD 0.0189 0.0716 0.1467
Onchocerca volvulus Cathepsin L homolog 0.0017 0.0012 0.0152
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0171 0.0643 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0029 0.0029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0224 0.0412
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0202 0.0529
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0189 0.0716 0.1467
Echinococcus multilocularis beta LACTamase domain containing family member 0.0189 0.0716 0.0716
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0045 0.0127 0.1766
Mycobacterium leprae ATP-dependent Clp protease proteolytic subunit 1 0.0059 0.0185 0.2571
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0171 0.0643 0.898
Echinococcus multilocularis snurportin 1 0.065 0.2605 0.2604
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0029 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Entamoeba histolytica acyl-coA synthetase, putative 0.0047 0.0138 0.183
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0193 0.0506
Loa Loa (eye worm) hypothetical protein 0.0197 0.0751 0.1968
Brugia malayi beta-lactamase family protein 0.0189 0.0716 0.1878
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0012 0.0167
Onchocerca volvulus 0.0017 0.0012 0.0152
Wolbachia endosymbiont of Brugia malayi ATP-dependent Clp protease proteolytic subunit 0.0171 0.0643 1
Entamoeba histolytica hypothetical protein 0.0144 0.0533 0.7093
Plasmodium falciparum cysteine proteinase falcipain 3 0.0017 0.0012 0.0169
Toxoplasma gondii ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein 0.0171 0.0643 0.4255
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0035 0.0089 0.0181
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0025 0.0045
Loa Loa (eye worm) hypothetical protein 0.0176 0.0663 0.1738
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0081 0.0164
Mycobacterium tuberculosis Conserved protein 0.0189 0.0716 0.1467
Schistosoma mansoni cpg binding protein 0.0099 0.0349 0.0644
Schistosoma mansoni carbonic anhydrase-related 0.0108 0.0386 0.0713
Toxoplasma gondii pyruvate dehydrogenase kinase, putative 0.033 0.1296 0.8575
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0023 0.0039 0.0071
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0254 0.0982 0.2575
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0138 0.183
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0012 0.003
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0047 0.0138 0.1918
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0025 0.005
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0025 0.0064
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Echinococcus multilocularis geminin 0.0513 0.2043 0.2042
Schistosoma mansoni hypothetical protein 0.008 0.027 0.0497
Treponema pallidum chemotaxis histidine kinase (cheA) 0.0053 0.0159 0.2332
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0022 0.0034 0.0062
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0029 0.0053
Brugia malayi Putative carbonic anhydrase 5 precursor 0.0199 0.076 0.1994
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0053 0.0159 0.0415
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Trypanosoma cruzi carbonic anhydrase-like protein, putative 0.0199 0.076 0.1994
Loa Loa (eye worm) hypothetical protein 0.0104 0.0368 0.0963
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0139 0.0256
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0029 0.0075
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0029 0.0075
Wolbachia endosymbiont of Brugia malayi DNA gyrase, topoisomerase II, B subunit, GyrB 0.0053 0.0159 0.2332
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0025 0.0045
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0159 0.1613
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0029 0.0075
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Brugia malayi jmjC domain containing protein 0.0017 0.0013 0.0031
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0138 0.1918
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0012 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Echinococcus multilocularis microtubule associated protein 2 0.0668 0.268 0.2679
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0045 0.0127 0.0332
Mycobacterium tuberculosis Two component sensor histidine kinase PrrB 0.0053 0.0159 0.0324
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0029 0.0029
Trypanosoma cruzi DNA topoisomerase II, putative 0.0053 0.0159 0.0415
Treponema pallidum DNA gyrase, subunit B (gyrB) 0.0053 0.0159 0.2332
Schistosoma mansoni hypothetical protein 0.008 0.027 0.0497
Loa Loa (eye worm) hypothetical protein 0.008 0.027 0.0706
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0013 0.0033
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0047 0.0138 0.0281
Mycobacterium tuberculosis Conserved protein 0.0053 0.0159 0.0324
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0035 0.0089 0.1225
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0138 0.1918
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0029 0.0053
Echinococcus multilocularis survival motor neuron protein 1 0.0234 0.0903 0.0902
Trichomonas vaginalis conserved hypothetical protein 0.0085 0.029 0.2947
Echinococcus granulosus Niemann Pick C1 protein 0.0197 0.0751 0.1387
Plasmodium vivax hypothetical protein, conserved 0.0053 0.0159 0.2209
Echinococcus granulosus sterol regulatory element binding protein 0.0085 0.029 0.0535
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0075
Trichomonas vaginalis two component sensor and regulator histidine kinase bacteria, putative 0.0053 0.0159 0.1611
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0013 0.0012
Schistosoma mansoni peptidase Clp (S14 family) 0.0171 0.0643 0.1189
Mycobacterium tuberculosis Possible two component sensor kinase 0.0053 0.0159 0.0324
Echinococcus granulosus expressed conserved protein 0.0185 0.0702 0.1296
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0012 0.0145
Brugia malayi Probable DNA topoisomerase II 0.0053 0.0159 0.0415
Wolbachia endosymbiont of Brugia malayi membrane associated signal transduction histidine kinase 0.0053 0.0159 0.2332
Mycobacterium ulcerans two component system membrane associated sensor kinase 0.0053 0.0159 0.2209
Trypanosoma brucei heat shock protein, putative 0.0053 0.0159 0.0417
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0025 0.0064
Echinococcus granulosus heat shock protein 90 0.0053 0.0159 0.0292
Echinococcus multilocularis Niemann Pick C1 protein 0.0197 0.0751 0.075
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0045 0.0127 0.0126
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0029 0.0053
Leishmania major hypothetical protein, conserved 0.0053 0.0159 0.0415
Onchocerca volvulus 0.0189 0.0716 1
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0031
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0029 0.0053
Echinococcus granulosus snurportin 1 0.065 0.2605 0.4816
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0029 0.0053
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0159 0.0415
Echinococcus multilocularis cpg binding protein 0.0099 0.0349 0.0348
Schistosoma mansoni hypothetical protein 0.0082 0.0278 0.0512
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0029 0.0075
Mycobacterium tuberculosis Two component sensory transduction histidine kinase MtrB 0.0053 0.0159 0.0324
Trichomonas vaginalis DNA topoisomerase II, putative 0.0053 0.0159 0.1611
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0013 0.0031
Echinococcus granulosus importin subunit beta 1 0.0061 0.0193 0.0356
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0029 0.04
Trypanosoma brucei heat shock protein 90, putative 0.0053 0.0159 0.0417
Echinococcus granulosus cathepsin L cysteine proteinase 0.0017 0.0012 0.002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0159 0.0415
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0075
Echinococcus multilocularis tumor protein p63 0.0327 0.1283 0.1283
Echinococcus multilocularis ATP dependent Clp protease proteolytic subunit 0.0171 0.0643 0.0643
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0186 0.0706 0.1305
Trichomonas vaginalis receptor histidine kinase, putative 0.0053 0.0159 0.1611
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0025 0.0064
Echinococcus multilocularis heat shock protein 90 0.0053 0.0159 0.0158
Echinococcus multilocularis expressed conserved protein 0.0185 0.0702 0.0701
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0059 0.0185 0.2571
Trichomonas vaginalis D-aminoacylase, putative 0.0189 0.0716 0.7292
Trichomonas vaginalis sensory transduction histidine kinase, putative 0.0053 0.0159 0.1611
Brugia malayi ecdysteroid receptor 0.0021 0.0029 0.0075
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0022 0.0034 0.0034
Leishmania major importin beta-1 subunit, putative 0.0049 0.0146 0.0381
Echinococcus granulosus mitogen activated protein kinase 3 0.0053 0.0159 0.0293
Loa Loa (eye worm) fibroinase 0.0017 0.0012 0.0028
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0029 0.0075
Trichomonas vaginalis receptor histidine kinase, putative 0.0053 0.0159 0.1611
Brugia malayi CHE-14 protein 0.0085 0.029 0.0759
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0025 0.0336
Mycobacterium tuberculosis Probable hydrolase 0.0189 0.0716 0.1467
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0053 0.0159 0.2209
Plasmodium falciparum heat shock protein 90 0.0053 0.0159 0.246
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0029 0.0075
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0025 0.0063
Plasmodium falciparum DNA topoisomerase VI, b subunit, putative 0.0053 0.0159 0.246
Giardia lamblia Heat shock protein HSP 90-alpha 0.0053 0.0159 0.9988
Brugia malayi jmjC domain containing protein 0.0068 0.0224 0.0585
Loa Loa (eye worm) TAR-binding protein 0.0124 0.0452 0.1183
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0199 0.076 0.1994
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0012 0.0111
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0186 0.0706 0.1852
Trypanosoma cruzi pyruvate dehydrogenase (lipoamide) kinase, putative 0.033 0.1296 0.3399
Trypanosoma brucei heat shock protein, putative 0.0053 0.0159 0.0417
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.039 0.0798
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0138 0.1918
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0075
Leishmania major GTP-binding protein, putative 0.0045 0.0127 0.0332
Brugia malayi Carbonic anhydrase like protein 2 precursor 0.0108 0.0386 0.1011
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.1878
Mycobacterium tuberculosis Conserved protein 0.0189 0.0716 0.1467
Echinococcus granulosus beta LACTamase domain containing family member 0.0189 0.0716 0.1324
Trypanosoma brucei heat shock protein, putative 0.0053 0.0159 0.0417
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0029 0.0029
Onchocerca volvulus 0.0017 0.0012 0.0152
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0017 0.0012 0.0169
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0012 0.015
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0189 0.0716 0.1467
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0017 0.0012 0.0111
Echinococcus granulosus mitogen activated protein kinase 0.0053 0.0159 0.0293
Loa Loa (eye worm) hypothetical protein 0.0047 0.0138 0.036
Onchocerca volvulus 0.0048 0.014 0.1943
Onchocerca volvulus DNA topoisomerase 2 homolog 0.0053 0.0159 0.2209
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0029 0.0075
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0199 0.0757 0.1399
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0013 0.0022
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0013 0.0022
Echinococcus granulosus heat shock protein 0.0053 0.0159 0.0292
Trichomonas vaginalis glucosylceramidase, putative 0.0175 0.0662 0.6735
Plasmodium falciparum endoplasmin, putative 0.0053 0.0159 0.246
Giardia lamblia Pms1-like protein 0.0053 0.0159 0.9988
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0202 0.0372
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0139 0.0364
Mycobacterium ulcerans two component sensory transduction histidine kinase MtrB 0.0053 0.0159 0.2209
Schistosoma mansoni patched 1 0.0085 0.029 0.0535
Leishmania major hypothetical protein, conserved 0.0189 0.0716 0.1878
Onchocerca volvulus Putative DNA topoisomerase 2, mitochondrial 0.0053 0.0159 0.2209
Plasmodium falciparum thioredoxin reductase 0.0017 0.0012 0.0167
Mycobacterium ulcerans DNA polymerase IV 0.002 0.0025 0.0342
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0012 0.0109
Echinococcus multilocularis protein patched 0.0085 0.029 0.0289
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0025 0.0024
Plasmodium vivax importin-beta 2, putative 0.0061 0.0193 0.2686
Schistosoma mansoni importin beta-1 0.0061 0.0193 0.0356
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0017 0.0012 0.0011
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0139 0.1936
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0108 0.0386 0.1011
Echinococcus granulosus dna polymerase kappa 0.002 0.0025 0.0045
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0081 0.0164
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0202 0.0529
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0202 0.0201
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0029 0.0053
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0029 0.0075
Toxoplasma gondii thioredoxin reductase 0.0048 0.0139 0.0917
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0029 0.0053
Plasmodium vivax hypothetical protein, conserved 0.0189 0.0716 1
Loa Loa (eye worm) hypothetical protein 0.0252 0.0974 0.2554
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0452 0.0834
Loa Loa (eye worm) heat shock protein 90 0.0053 0.0159 0.0415
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0025 0.032
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0029 0.0075
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0013 0.0078
Brugia malayi beta-lactamase 0.0189 0.0716 0.1878
Loa Loa (eye worm) jmjC domain-containing protein 0.0068 0.0224 0.0585
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0025 0.0044
Echinococcus granulosus ATP dependent Clp protease proteolytic subunit 0.0171 0.0643 0.1189
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0171 0.0643 1
Brugia malayi CXXC zinc finger family protein 0.0094 0.0327 0.0857
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0045 0.0127 0.0332
Onchocerca volvulus 0.0094 0.0327 0.4563
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0625 0.6361
Loa Loa (eye worm) hypothetical protein 0.002 0.0025 0.0064
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0053 0.0159 0.0415
Trypanosoma cruzi heat shock protein 85, putative 0.0053 0.0159 0.0415
Mycobacterium ulcerans ATP-dependent Clp protease proteolytic subunit 0.0171 0.0643 0.898
Brugia malayi Cathepsin L-like precursor 0.0017 0.0012 0.0028
Echinococcus multilocularis GPCR, family 2 0.008 0.027 0.0269
Echinococcus multilocularis cysteine protease 0.0017 0.0012 0.0011
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0017 0.0012 0.0028
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Trichomonas vaginalis D-aminoacylase, putative 0.0189 0.0716 0.7292
Echinococcus multilocularis cysteine protease 0.0017 0.0012 0.0011
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0045 0.0127 0.0837
Loa Loa (eye worm) hypothetical protein 0.0025 0.0047 0.0121
Brugia malayi Eukaryotic-type carbonic anhydrase family protein 0.0108 0.0386 0.1011
Trypanosoma brucei Heat shock protein 83, putative 0.0053 0.0159 0.0417
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0029 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0075
Mycobacterium ulcerans two component sensor histidine kinase TrcS 0.0053 0.0159 0.2209
Trypanosoma cruzi DNA topoisomerase II, putative 0.0053 0.0159 0.0415
Chlamydia trachomatis DNA gyrase subunit B 0.0053 0.0159 0.2332
Trypanosoma cruzi mitochondrial DNA topoisomerase II, putative 0.0053 0.0159 0.0415
Trypanosoma brucei heat shock protein, putative 0.0053 0.0159 0.0417
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0017 0.0012 0.0169
Schistosoma mansoni hypothetical protein 0.0144 0.0533 0.0984
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.1878
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0254 0.0982 0.2575
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0144 0.0533 0.0984
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0982 1
Schistosoma mansoni niemann-pick C1 (NPC1) 0.02 0.0763 0.141
Trypanosoma brucei DNA topoisomerase ii 0.0053 0.0159 0.0417
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0035 0.0089 0.1232
Echinococcus granulosus GTP binding nuclear protein Ran 0.0045 0.0127 0.0234
Echinococcus granulosus carbonic anhydrase 0.0108 0.0386 0.0713
Echinococcus multilocularis tar DNA binding protein 0.0124 0.0452 0.0451
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0029 0.0075
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0025 0.025
Echinococcus multilocularis protein dispatched 1 0.0097 0.0339 0.0338
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.008 0.027 0.0706
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0029 0.0053
Leishmania major DNA topoisomerase ii 0.0053 0.0159 0.0415
Onchocerca volvulus 0.0017 0.0012 0.0152
Mycobacterium tuberculosis Probable reductase 0.0109 0.039 0.0798
Plasmodium falciparum ATP-dependent Clp protease proteolytic subunit 0.0059 0.0185 0.2863
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Onchocerca volvulus 0.0017 0.0012 0.0152
Leishmania major developmentally regulated phosphoprotein-like protein 0.0944 0.3811 1
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0017 0.0012 0.0028
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0031 0.0304
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0029 0.0075
Plasmodium vivax acyl-CoA synthetase, putative 0.0035 0.0089 0.1232
Toxoplasma gondii histone lysine methyltransferase SET1 0.0177 0.067 0.4434
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0045 0.0127 0.1967
Trypanosoma brucei carbonic anhydrase-like protein 0.0199 0.076 0.1995
Mycobacterium tuberculosis Two component sensor histidine kinase TrcS 0.0053 0.0159 0.0324
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0085 0.029 0.0759
Plasmodium falciparum thioredoxin reductase 0.0048 0.0139 0.2156
Plasmodium falciparum glutathione reductase 0.0017 0.0012 0.0167
Mycobacterium ulcerans two component regulator - sensor kinase 0.0053 0.0159 0.2209
Mycobacterium leprae TWO COMPONENT SENSOR HISTIDINE KINASE PRRB 0.0053 0.0159 0.2209
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0029 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0053 0.0159 0.1611
Toxoplasma gondii ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein 0.0383 0.1511 1
Entamoeba histolytica cysteine proteinase, putative 0.0017 0.0012 0.0145
Schistosoma mansoni ap endonuclease 0.002 0.0025 0.0044
Echinococcus granulosus phd:f box containing protein 0.0017 0.0013 0.0022
Schistosoma mansoni carbonic anhydrase 0.0108 0.0386 0.0713
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0013 0.0022
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Leishmania major trypanothione reductase 0.0048 0.0139 0.0364
Schistosoma mansoni endoplasmin 0.0053 0.0159 0.0292
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0029 0.0075
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0012 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Treponema pallidum ATP-dependent Clp protease proteolytic subunit 0.0059 0.0185 0.2742
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Loa Loa (eye worm) latrophilin receptor protein 2 0.008 0.027 0.0706
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0012 0.0109
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Schistosoma mansoni ap endonuclease 0.002 0.0025 0.0044
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0625 0.6361
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Schistosoma mansoni heat shock protein 0.0053 0.0159 0.0292
Plasmodium vivax glutathione reductase, putative 0.0048 0.0139 0.1936
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0047 0.0717
Schistosoma mansoni cathepsin F (C01 family) 0.0017 0.0012 0.002
Entamoeba histolytica hypothetical protein 0.0144 0.0533 0.7093
Mycobacterium ulcerans two component sensor histidine kinase PrrB 0.0053 0.0159 0.2209
Onchocerca volvulus Cathepsin F homolog 0.0017 0.0012 0.0152
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0023 0.0039 0.0038
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0031 0.0304
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0144 0.0533 0.0532
Echinococcus granulosus carbonic anhydrase II 0.0199 0.076 0.1405
Brugia malayi Cathepsin L-like precursor 0.0017 0.0012 0.0028
Entamoeba histolytica hypothetical protein 0.0144 0.0533 0.7093
Schistosoma mansoni pyruvate dehydrogenase 0.0892 0.3596 0.6651
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0189 0.0716 0.1878
Trypanosoma brucei protein kinase, putative 0.0053 0.0159 0.0417
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0045 0.0127 0.0334
Mycobacterium ulcerans hypothetical protein 0.0047 0.0138 0.1918
Mycobacterium leprae conserved hypothetical protein 0.0189 0.0716 1
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0982 1
Schistosoma mansoni coup transcription factor 0.0021 0.0029 0.0053
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.008 0.027 0.0497
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0025 0.0066
Schistosoma mansoni carbonic anhydrase-related 0.0108 0.0386 0.0713
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0017 0.0012 0.0022
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0025 0.0064
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0029 0.0053
Loa Loa (eye worm) hypothetical protein 0.0171 0.0643 0.1686
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0013 0.0022
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0031
Onchocerca volvulus 0.0021 0.0029 0.04
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0029 0.0029
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0252 0.0974 0.2554
Mycobacterium tuberculosis DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) 0.0053 0.0159 0.0324
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0202 0.0201
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0047 0.0138 0.1918
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0047 0.0121
Mycobacterium tuberculosis Conserved protein 0.0189 0.0716 0.1467
Brugia malayi DNA topoisomerase II, alpha isozyme 0.0053 0.0159 0.0415
Entamoeba histolytica Ran family GTPase 0.0045 0.0127 0.1686
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0029 0.0062 0.0114
Trypanosoma brucei heat shock protein, putative 0.0053 0.0159 0.0417
Echinococcus multilocularis Niemann Pick C1 protein 0.0282 0.1097 0.1096
Plasmodium falciparum importin beta, putative 0.0061 0.0193 0.2991
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.039 0.0798
Brugia malayi RNA binding protein 0.0124 0.0452 0.1183
Trypanosoma cruzi heat shock protein 85, putative 0.0053 0.0159 0.0415
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0031 0.0304
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.039 0.0798
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0025 0.0064
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0013 0.0183
Schistosoma mansoni DNA topoisomerase II 0.0053 0.0159 0.0292
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.1878
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0452 0.0834
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0159 0.1613
Echinococcus granulosus cathepsin l1 0.0017 0.0012 0.002
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0025 0.0063
Brugia malayi Cathepsin L-like precursor 0.0017 0.0012 0.0028
Mycobacterium tuberculosis Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) 0.0112 0.0402 0.0823
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0202 0.0529
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0012 0.003
Schistosoma mansoni hypothetical protein 0.1334 0.5407 1
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0012 0.003
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0025 0.005
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0452 0.0834
Echinococcus multilocularis peptidase Clp (S14 family) 0.0112 0.0402 0.0402
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0012 0.0028
Onchocerca volvulus 0.0048 0.0139 0.1936
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0047 0.0138 0.1918
Brugia malayi jmjC domain containing protein 0.0063 0.0202 0.0527
Schistosoma mansoni hypothetical protein 0.0082 0.0278 0.0512
Mycobacterium tuberculosis Probable sensor protein KdpD 0.0053 0.0159 0.0324
Brugia malayi DNA gyrase/topoisomerase IV, A subunit family protein 0.0053 0.0159 0.0415
Brugia malayi MAP kinase sur-1 0.0053 0.0159 0.0415
Brugia malayi nuclear hormone receptor 0.0021 0.0029 0.0075
Mycobacterium ulcerans DNA gyrase subunit B 0.0053 0.0159 0.2209
Giardia lamblia DINP protein human, muc B family 0.002 0.0025 0.0933
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0029 0.0029
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0025 0.0063
Mycobacterium leprae PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) 0.0112 0.0402 0.5611
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0625 0.6361
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0231
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0029 0.0053
Leishmania major hypothetical protein, conserved 0.0017 0.0013 0.0031
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0189 0.0716 0.1878
Loa Loa (eye worm) glutathione reductase 0.0048 0.0139 0.0364
Mycobacterium ulcerans two component sensor kinase MprB 0.0053 0.0159 0.2209
Trichomonas vaginalis CMGC family protein kinase 0.0053 0.0159 0.1613
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0625 0.6361
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0029 0.04
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0021 0.0031 0.0304
Loa Loa (eye worm) hypothetical protein 0.0944 0.3811 1
Plasmodium falciparum DNA topoisomerase 2 0.0053 0.0159 0.246
Brugia malayi jmjC domain containing protein 0.0017 0.0013 0.0031
Leishmania major cysteine peptidase A (CPA) 0.0017 0.0012 0.0028
Loa Loa (eye worm) RNA binding protein 0.0124 0.0452 0.1183
Brugia malayi Cathepsin L-like precursor 0.0017 0.0012 0.0028
Mycobacterium ulcerans beta-lactamase 0.0189 0.0716 1
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0025 0.0066
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0013 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Echinococcus granulosus GPCR family 2 0.008 0.027 0.0497
Echinococcus multilocularis mitogen activated protein kinase 0.0053 0.0159 0.0158
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Mycobacterium ulcerans hypothetical protein 0.0189 0.0716 1
Echinococcus multilocularis carbonic anhydrase 0.0108 0.0386 0.0385
Mycobacterium ulcerans lipase LipD 0.0189 0.0716 1
Schistosoma mansoni tar DNA-binding protein 0.0124 0.0452 0.0834
Plasmodium vivax DNA topoisomerase II, putative 0.0053 0.0159 0.2209
Brugia malayi kinase, mitochondrial precursor 0.0944 0.3811 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0029 0.0075
Loa Loa (eye worm) TOPoisomerase family member 0.0053 0.0159 0.0415
Echinococcus granulosus tumor protein p63 0.0327 0.1283 0.2372
Leishmania major cathepsin L-like protease 0.0063 0.0202 0.0529
Echinococcus granulosus carbonic anhydrase 0.0108 0.0386 0.0713
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.018 0.047
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.039 0.5438
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0045 0.0127 0.0332
Echinococcus granulosus DNA topoisomerase 2 alpha 0.0053 0.0159 0.0292
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0176 0.0663 0.8834
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0025 0.021
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0025 0.0045
Schistosoma mansoni ran 0.0045 0.0127 0.0234
Echinococcus multilocularis carbonic anhydrase 0.0108 0.0386 0.0385
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0031 0.0304
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0029 0.0053
Echinococcus multilocularis sterol regulatory element binding protein 0.0085 0.029 0.0289
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0012 0.0028
Brugia malayi jmjC domain containing protein 0.0017 0.0013 0.0031
Brugia malayi TAR-binding protein 0.0124 0.0452 0.1183
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.014 0.0257
Mycobacterium leprae Probable two-component sensor kinase 0.0053 0.0159 0.2209
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0029 0.0075
Toxoplasma gondii DNA topoisomerase 2, putative 0.0053 0.0159 0.1047
Loa Loa (eye worm) hypothetical protein 0.0108 0.0386 0.1011
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0013 0.0031
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0013 0.0012
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0025 0.0064
Onchocerca volvulus 0.0189 0.0716 1
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0025 0.0063
Trichomonas vaginalis importin beta-1, putative 0.0049 0.0146 0.1478
Trypanosoma brucei DNA topoisomerase II beta, putative 0.0053 0.0159 0.0417
Loa Loa (eye worm) hypothetical protein 0.0061 0.0193 0.0504
Brugia malayi Thioredoxin reductase 0.0048 0.0139 0.0364
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Mycobacterium ulcerans two component sensor histidine kinase SenX3 0.0053 0.0159 0.2209
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0012 0.002
Echinococcus granulosus cathepsin l cysteine peptidase 0.0017 0.0012 0.002
Echinococcus granulosus tar DNA binding protein 0.0124 0.0452 0.0834
Echinococcus granulosus cpg binding protein 0.0099 0.0349 0.0644
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0139 0.0364
Mycobacterium tuberculosis Possible two component system response sensor kinase membrane associated PhoR 0.0053 0.0159 0.0324
Brugia malayi hypothetical protein 0.0016 0.001 0.0025
Trichomonas vaginalis esterase, putative 0.0189 0.0716 0.7292
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Mycobacterium ulcerans acyl-CoA synthetase 0.0047 0.0138 0.1918
Trichomonas vaginalis heat shock protein, putative 0.0053 0.0159 0.1611
Loa Loa (eye worm) CXXC zinc finger family protein 0.0094 0.0327 0.0857
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Trypanosoma brucei DNA topoisomerase II alpha, putative 0.0053 0.0159 0.0417
Trichomonas vaginalis sensory transduction histidine kinase bacterial, putative 0.0053 0.0159 0.1611
Brugia malayi hypothetical protein 0.0234 0.0903 0.2367
Brugia malayi glutathione reductase 0.0048 0.0139 0.0364
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0047 0.0305
Schistosoma mansoni serine/threonine protein kinase 0.0053 0.0159 0.0293
Mycobacterium tuberculosis Probable two component sensor kinase 0.0053 0.0159 0.0324
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0034 0.0081 0.0164
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0025 0.0065
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0053 0.0159 0.0417
Brugia malayi nuclear receptor NHR-88 0.0021 0.0029 0.0075
Trypanosoma cruzi developmentally regulated phosphoprotein, putative 0.0944 0.3811 1
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0029 0.0075
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0053 0.0159 0.0415
Trypanosoma cruzi cysteine peptidase, putative 0.0017 0.0012 0.0028
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0029 0.0075
Toxoplasma gondii heat shock protein 90, putative 0.0053 0.0159 0.1047
Trypanosoma brucei importin beta-1 subunit, putative 0.0061 0.0193 0.0506
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0012 0.0011
Schistosoma mansoni jumonji/arid domain-containing protein 0.0068 0.0224 0.0412
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0186 0.0706 0.1305
Echinococcus multilocularis dna polymerase eta 0.002 0.0025 0.0025
Loa Loa (eye worm) hypothetical protein 0.0017 0.0013 0.0031
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0017 0.0012 0.0111
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0012 0.0167
Schistosoma mansoni DNA polymerase eta 0.002 0.0025 0.0045
Loa Loa (eye worm) histone methyltransferase 0.0029 0.0062 0.0162
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0053 0.0159 0.0415
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0199 0.076 0.1405
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.039 0.0798
Echinococcus multilocularis DNA topoisomerase 2 alpha 0.0053 0.0159 0.0158
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Leishmania major pyruvate dehydrogenase (lipoamide) kinase, putative 0.033 0.1296 0.3399
Entamoeba histolytica acyl-CoA synthetase, putative 0.0047 0.0138 0.183
Toxoplasma gondii ABC1 family protein 0.0189 0.0716 0.4738
Mycobacterium tuberculosis Possible penicillin-binding protein 0.1205 0.488 1
Schistosoma mansoni microtubule-associated protein tau 0.0668 0.268 0.4955
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0013 0.0022
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0147 0.0384
Loa Loa (eye worm) eukaryotic-type carbonic anhydrase 0.0199 0.076 0.1994
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0025 0.0327
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0025 0.0245
Schistosoma mansoni cpg binding protein 0.0099 0.0349 0.0644
Mycobacterium tuberculosis Two component sensor histidine kinase DevS 0.0053 0.0159 0.0324
Loa Loa (eye worm) hypothetical protein 0.0108 0.0386 0.1011
Brugia malayi Probable ClpP-like protease 0.0171 0.0643 0.1686
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0029 0.0053
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Brugia malayi Cathepsin L-like precursor 0.0017 0.0012 0.0028
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Echinococcus granulosus Protein patched homolog 1 0.0085 0.029 0.0535
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0012 0.0011
Loa Loa (eye worm) carbonic anhydrase 3 0.0199 0.076 0.1994
Leishmania major cathepsin L-like protease 0.0017 0.0012 0.0028
Trypanosoma brucei heat shock protein, putative 0.0053 0.0159 0.0417
Schistosoma mansoni hypothetical protein 0.0513 0.2043 0.3778
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0031 0.0304
Trypanosoma brucei heat shock protein 90, putative 0.0053 0.0159 0.0417
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Leishmania major cathepsin L-like protease 0.0017 0.0012 0.0028
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Entamoeba histolytica heat shock protein 90, putative 0.0053 0.0159 0.2108
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0029 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0029 0.0075
Schistosoma mansoni hypothetical protein 0.0513 0.2043 0.3778
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0013 0.0022
Loa Loa (eye worm) cysteine protease 0.0017 0.0012 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Schistosoma mansoni hypothetical protein 0.008 0.027 0.0497
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0186 0.0706 0.1852
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0139 0.0284
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0231
Onchocerca volvulus 0.0017 0.0012 0.0152
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0031 0.0304
Entamoeba histolytica Acid sphingomyelinase-like phosphodiesterase, putative 0.0176 0.0663 0.8834
Mycobacterium ulcerans two component system response phosphate sensor kinase, PhoR 0.0053 0.0159 0.2209
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Brugia malayi Calcitonin receptor-like protein seb-1 0.0252 0.0974 0.2554
Schistosoma mansoni hypothetical protein 0.0108 0.0386 0.0713
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0029 0.0029
Plasmodium vivax DNA gyrase subunit B, putative 0.0053 0.0159 0.2209
Brugia malayi Papain family cysteine protease containing protein 0.0017 0.0012 0.0028
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0013 0.0022
Echinococcus granulosus lysine specific demethylase 5A 0.0068 0.0224 0.0412
Leishmania major cathepsin L-like protease 0.0017 0.0012 0.0028
Leishmania major heat shock protein 83-1 0.0053 0.0159 0.0415
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0197 0.0751 1
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0012 0.0028
Trypanosoma cruzi hypothetical protein, conserved 0.0189 0.0716 0.1878
Loa Loa (eye worm) hypothetical protein 0.0234 0.0903 0.2367
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0139 0.0364
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0029 0.0053
Echinococcus granulosus peptidase Clp S14 family 0.0112 0.0402 0.0743
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0029 0.0029
Brugia malayi hypothetical protein 0.0025 0.0047 0.0121
Loa Loa (eye worm) hypothetical protein 0.0172 0.0648 0.1698
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0029 0.0053
Schistosoma mansoni carbonic anhydrase II (carbonate dehydratase II) 0.0199 0.076 0.1405
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0075
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0139 0.0139
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0189 0.0716 0.1467
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0202 0.0531
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Brugia malayi Niemann-Pick C1 protein precursor 0.0197 0.0751 0.1968
Entamoeba histolytica heat shock protein 90, putative 0.0053 0.0159 0.2108
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0031 0.0304
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0029 0.0053
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0013 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0025 0.0066
Loa Loa (eye worm) hypothetical protein 0.0189 0.0716 0.1878
Schistosoma mansoni hypothetical protein 0.0172 0.0648 0.1197
Leishmania major cathepsin L-like protease 0.0063 0.0202 0.0529
Loa Loa (eye worm) hypothetical protein 0.0108 0.0386 0.1011
Loa Loa (eye worm) beta-lactamase 0.0189 0.0716 0.1878
Trichomonas vaginalis glucosylceramidase, putative 0.0254 0.0982 1
Plasmodium falciparum DNA gyrase subunit B 0.0053 0.0159 0.246
Loa Loa (eye worm) hypothetical protein 0.0021 0.0029 0.0075
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0013 0.0031
Brugia malayi AMP-binding enzyme family protein 0.0047 0.0138 0.036
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0202 0.0529
Leishmania major cathepsin L-like protease 0.0017 0.0012 0.0028
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0025 0.0025
Leishmania major cathepsin L-like protease 0.0063 0.0202 0.0529
Trypanosoma cruzi hypothetical protein, conserved 0.0189 0.0716 0.1878
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0012 0.015
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0053 0.0159 0.0415
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0047 0.0644
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0013 0.0078
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0029 0.0075
Mycobacterium tuberculosis Probable lipase LipE 0.0189 0.0716 0.1467
Toxoplasma gondii heat shock protein HSP90 0.0053 0.0159 0.1047
Echinococcus multilocularis heat shock protein 0.0053 0.0159 0.0158
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0029 0.0053
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0025 0.0336
Mycobacterium leprae Probable lipase LipE 0.0189 0.0716 1
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0012 0.0028
Schistosoma mansoni hypothetical protein 0.008 0.027 0.0497
Brugia malayi jmjC domain containing protein 0.0017 0.0013 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0625 0.6361
Mycobacterium tuberculosis Two component sensor kinase MprB 0.0053 0.0159 0.0324
Echinococcus multilocularis Pyruvate dehydrogenase (lipoamide) kinase 0.0944 0.3811 0.3811
Leishmania major DNA polymerase eta, putative 0.002 0.0025 0.0064
Echinococcus granulosus Pyruvate dehydrogenase lipoamide kinase 0.0944 0.3811 0.7049
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0025 0.0064
Leishmania major 4-coumarate:coa ligase-like protein 0.0047 0.0138 0.036
Brugia malayi latrophilin 2 splice variant baaae 0.0172 0.0648 0.1698
Leishmania major hypothetical protein, conserved 0.0025 0.0047 0.0121
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.008 0.027 0.0269
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0025 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0029 0.0075
Plasmodium vivax ATP-dependent Clp protease proteolytic subunit, putative 0.0171 0.0643 0.898
Chlamydia trachomatis DNA gyrase subunit B 0.0053 0.0159 0.2332
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0029 0.04
Loa Loa (eye worm) hypothetical protein 0.0035 0.0089 0.0231
Plasmodium falciparum glutathione reductase 0.0048 0.0139 0.2156
Loa Loa (eye worm) hypothetical protein 0.0048 0.014 0.0365
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0021 0.0031 0.0304
Schistosoma mansoni ran 0.0045 0.0127 0.0234
Loa Loa (eye worm) hypothetical protein 0.0017 0.0012 0.0028
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0029 0.0075
Plasmodium vivax JmjC domain containing protein 0.0017 0.0013 0.0164
Toxoplasma gondii hypothetical protein 0.0059 0.0185 0.1218
Trypanosoma brucei heat shock protein, putative 0.0053 0.0159 0.0417
Echinococcus multilocularis cathepsin L cysteine protease 0.0017 0.0012 0.0011
Trypanosoma cruzi Heat shock protein 83, putative 0.0053 0.0159 0.0415
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0017 0.0012 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.0166 0.0625 0.6361
Loa Loa (eye worm) hypothetical protein 0.0085 0.029 0.0759
Brugia malayi RNA, U transporter 1 0.0173 0.0653 0.171
Onchocerca volvulus 0.0017 0.0012 0.0152

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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