Detailed information for compound 764321

Basic information

Technical information
  • TDR Targets ID: 764321
  • Name: 2-[4-(3-nitrophenyl)-1-oxophthalazin-2-yl]-N- propylacetamide
  • MW: 366.371 | Formula: C19H18N4O4
  • H donors: 1 H acceptors: 4 LogP: 2.93 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCNC(=O)Cn1nc(c2cccc(c2)[N+](=O)[O-])c2c(c1=O)cccc2
  • InChi: 1S/C19H18N4O4/c1-2-10-20-17(24)12-22-19(25)16-9-4-3-8-15(16)18(21-22)13-6-5-7-14(11-13)23(26)27/h3-9,11H,2,10,12H2,1H3,(H,20,24)
  • InChiKey: DLWWQNCETLSUFD-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 2-[4-(3-nitrophenyl)-1-oxo-phthalazin-2-yl]-N-propyl-acetamide
  • 2-[4-(3-nitrophenyl)-1-oxo-2-phthalazinyl]-N-propylacetamide
  • 2-[1-keto-4-(3-nitrophenyl)phthalazin-2-yl]-N-propyl-acetamide
  • 2-[4-(3-nitrophenyl)-1-oxo-phthalazin-2-yl]-N-propyl-ethanamide
  • STOCK5S-13710
  • ZINC01887429

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0403 0.0403
Echinococcus granulosus intermediate filament protein 0.0027 0.018 0.018
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0086 0.0084
Echinococcus granulosus fmrfamide receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis lamin dm0 0.0027 0.018 0.018
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0022 0.0022
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0086 0.0086
Echinococcus granulosus roundabout 2 0.0013 0.0028 0.0028
Echinococcus multilocularis epidermal growth factor receptor 0.0422 0.4475 0.4475
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0061 0.0549 0.0549
Echinococcus granulosus lamin 0.0027 0.018 0.018
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0014 0.0031 0.0178
Schistosoma mansoni single-minded 0.0049 0.0418 0.0417
Brugia malayi glutathione reductase 0.0048 0.0403 0.0403
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0175 0.1786 0.1786
Onchocerca volvulus 0.0027 0.018 0.103
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0086 0.0086
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0514 0.0513
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Echinococcus granulosus tyrosine protein kinase Src42A 0.0061 0.0549 0.0549
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.0346 0.3646 0.3636
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0289 0.0281
Echinococcus multilocularis Immunoglobulin 0.0021 0.0113 0.0113
Echinococcus granulosus GPCR family 3 C terminal 0.0014 0.0031 0.0031
Echinococcus multilocularis tyrosine protein kinase Srms 0.0051 0.0436 0.0436
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Leishmania major 0.093 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0056 0.0056
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0086 0.0086
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) TK/EGFR protein kinase 0.078 0.837 0.837
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0289 0.0281
Echinococcus multilocularis mitogen activated protein kinase 11 0.0128 0.1277 0.1277
Mycobacterium tuberculosis Probable reductase 0.0109 0.1069 0.8837
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni opsin-like receptor 0.0019 0.0086 0.0084
Brugia malayi Thioredoxin reductase 0.0048 0.0403 0.0403
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0086 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1078 0.3961
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0056 0.0056
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0063 0.2238
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1078 0.3961
Entamoeba histolytica protein kinase, putative 0.0012 0.0014 0.0134
Echinococcus granulosus twitchin 0.0029 0.0198 0.0198
Schistosoma mansoni hypothetical protein 0.0019 0.0086 0.0084
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0038 0.0029
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0074 0.0074
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0051 0.0436 0.0436
Echinococcus granulosus tyrosine kinase 0.0019 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0014 0.0031 0.003
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0063 0.0048
Brugia malayi jmjC domain containing protein 0.0059 0.053 0.053
Loa Loa (eye worm) inositol-1 0.0037 0.0289 0.0289
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Brugia malayi Cytochrome P450 family protein 0.0016 0.0057 0.0057
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0453 0.0453
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0022 0.0082
Echinococcus granulosus tyrosine protein kinase shark 0.0021 0.0117 0.0117
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Brugia malayi Receptor family ligand binding region containing protein 0.0021 0.0117 0.0117
Brugia malayi Receptor family ligand binding region containing protein 0.0019 0.0086 0.0086
Schistosoma mansoni 6-phosphofructokinase 0.011 0.1078 0.1077
Echinococcus multilocularis Ankyrin 0.0015 0.0043 0.0043
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0548 0.0548
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0514 0.0514
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0113 0.0112
Echinococcus multilocularis tyrosine protein kinase Abl 0.0111 0.1095 0.1095
Brugia malayi Metabotropic glutamate receptor precursor. 0.0084 0.0793 0.0793
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Brugia malayi phosphofructokinase 0.011 0.1078 0.1078
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.1078 0.1078
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0056 0.0054
Echinococcus granulosus 6 phosphofructokinase 0.011 0.1078 0.1078
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0034 0.0258 0.0258
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0059
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0034 0.0258 0.0258
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0028 0.0028
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0112 0.0112
Echinococcus multilocularis mitogen activated protein kinase 14 0.0128 0.1277 0.1277
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0021 0.0112 0.0112
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0453 0.1666
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0022 0.0082
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0028 0.0028
Echinococcus multilocularis neuroglian 0.0013 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.1069 0.8837
Schistosoma mansoni cpg binding protein 0.0031 0.0217 0.0216
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0429 0.455 0.455
Onchocerca volvulus 0.0029 0.0199 0.114
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0086 0.0086
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0063 0.0055
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0112 0.0112
Schistosoma mansoni nck2/grb4 0.0021 0.0112 0.0111
Onchocerca volvulus 0.0021 0.0116 0.0664
Loa Loa (eye worm) RecQ helicase 0.0022 0.0118 0.0118
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0022 0.0082
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0206 0.1912
Brugia malayi 6-phosphofructokinase 0.011 0.1078 0.1078
Echinococcus granulosus mitogen activated protein kinase 11 0.0128 0.1277 0.1277
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0022 0.0082
Schistosoma mansoni polycystin 1-related 0.004 0.0317 0.0315
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0021 0.0112 0.0111
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1846 0.6782
Brugia malayi jmjC domain containing protein 0.0016 0.0056 0.0056
Echinococcus multilocularis serotonin receptor 0.0019 0.0086 0.0086
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0086 0.0084
Brugia malayi Peroxidasin 0.0013 0.0028 0.0028
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0128 0.1277 0.127
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Brugia malayi sulfakinin receptor protein 0.0019 0.0086 0.0086
Brugia malayi P38 map kinase family protein 2 0.0128 0.1277 0.1277
Schistosoma mansoni protein kinase 0.0012 0.0015 0.0014
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.093 1 1
Brugia malayi SH2 domain containing protein 0.0021 0.0116 0.0116
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0086 0.0086
Schistosoma mansoni rab6-interacting 0.004 0.0317 0.0315
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0118 0.0433
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0693 0.0693
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.1078 0.1078
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0118 0.0118
Echinococcus granulosus tyrosine kinase 0.0051 0.0436 0.0436
Onchocerca volvulus 0.004 0.0317 0.1814
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni protein kinase 0.0012 0.0015 0.0014
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0061 0.0549 0.0549
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0403 0.0403
Echinococcus multilocularis tyrosine protein kinase ABL1 0.023 0.2382 0.2382
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0013 0.0028 0.0027
Echinococcus granulosus cpg binding protein 0.0031 0.0217 0.0217
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Schistosoma mansoni tyrosine kinase 0.0411 0.4358 0.4358
Loa Loa (eye worm) glutamate receptor 0.0033 0.0241 0.0241
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0012 0.0014 0.0134
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0403 1
Onchocerca volvulus 0.0019 0.0086 0.0491
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0021 0.0116 0.0116
Onchocerca volvulus 0.0027 0.018 0.103
Brugia malayi Melatonin receptor type 1A 0.0019 0.0086 0.0086
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0279 0.0279
Onchocerca volvulus 0.0021 0.0116 0.0664
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0056 0.0056
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.4378 0.4378
Onchocerca volvulus 0.0019 0.0086 0.0491
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0403 0.0395
Schistosoma mansoni tyrosine kinase 0.0032 0.0229 0.0227
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0041
Schistosoma mansoni protein kinase 0.0012 0.0015 0.0014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0086 0.0086
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0022 0.0014
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0055
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0453 0.0439
Echinococcus granulosus roundabout 2 0.0013 0.0028 0.0028
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0116 0.0116
Giardia lamblia Kinase, NEK 0.0011 0.0001 0.003
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0289 0.1063
Echinococcus multilocularis activin receptor type 0.0012 0.0015 0.0015
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0418 0.0417
Schistosoma mansoni jumonji domain containing protein 0.0059 0.053 0.0528
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0086 0.0086
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0086 0.0086
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0128 0.1277 0.127
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0289 0.0274
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0471 0.0471
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Brugia malayi GnHR receptor homolog 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus dnaJ subfamily B 0.0413 0.4378 0.4378
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0021 0.0117 0.0117
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0086 0.0086
Echinococcus multilocularis RUN 0.004 0.0317 0.0317
Brugia malayi hypothetical protein 0.004 0.0317 0.0317
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0086 0.0084
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0206 0.0191
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.1078 0.1078
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0086 0.0491
Schistosoma mansoni vesicular amine transporter 0.0021 0.0113 0.0112
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0022 0.0082
Loa Loa (eye worm) intermediate filament protein 0.0027 0.018 0.018
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Echinococcus multilocularis insulin receptor 0.0254 0.2642 0.2642
Schistosoma mansoni tyrosine kinase 0.0254 0.2642 0.2641
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0206 0.4546
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0056 0.0054
Schistosoma mansoni tyrosine kinase 0.0219 0.2267 0.2266
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0022 0.0022
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0069 0.0067
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.1069 0.8837
Onchocerca volvulus 0.0019 0.0086 0.0491
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0403 0.2985
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0022 0.0014
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.1078 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0086 0.0086
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0013 0.0028 0.016
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0289 0.0281
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0086 0.0086
Onchocerca volvulus Netrin receptor homolog 0.0021 0.0111 0.0636
Echinococcus granulosus bloom syndrome protein 0.0022 0.0118 0.0118
Trypanosoma brucei protein kinase, putative 0.0012 0.0015 0.0007
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis serotonin receptor 0.0019 0.0086 0.0086
Brugia malayi Raf kinase 0.0221 0.2286 0.2286
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0436 0.0436
Schistosoma mansoni growth factor receptor-bound protein 0.0021 0.0112 0.0111
Brugia malayi RhoGAP domain containing protein 0.0018 0.0082 0.0082
Echinococcus multilocularis peroxidasin 0.0013 0.0028 0.0028
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Echinococcus granulosus orexin receptor type 2 0.0019 0.0086 0.0086
Schistosoma mansoni microtubule-associated protein tau 0.0697 0.7467 0.7466
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1846 0.6782
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0116 0.0116
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0481 0.0467
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.1069 0.8837
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Echinococcus granulosus sex peptide receptor 0.0019 0.0086 0.0086
Brugia malayi Doublecortin family protein 0.004 0.0317 0.0317
Loa Loa (eye worm) doublecortin family protein 0.004 0.0317 0.0317
Plasmodium falciparum glutathione reductase 0.0017 0.0063 0.1244
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0021 0.0113 0.0112
Schistosoma mansoni septate junction protein 0.0013 0.0028 0.0027
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0057 0.0049
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0016 0.0016
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0063 0.0233
Schistosoma mansoni cell adhesion molecule 0.0013 0.0028 0.0027
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.1195 0.1195
Schistosoma mansoni neuropeptide receptor 0.0019 0.0086 0.0084
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0086 0.0084
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0042 0.0042
Loa Loa (eye worm) TK protein kinase 0.004 0.032 0.032
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0015 0.0007
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0041 0.004
Onchocerca volvulus 0.0021 0.0116 0.0664
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0041 0.0041
Echinococcus granulosus tyrosine protein kinase Lyn 0.0063 0.0564 0.0564
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0039 0.0305 0.0305
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0103 0.1004 0.1004
Echinococcus multilocularis roundabout 2 0.0013 0.0028 0.0028
Echinococcus multilocularis tyrosine kinase 0.0021 0.0116 0.0116
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1078 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0086 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0279 0.2172
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0086 0.0084
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0041 0.0041
Onchocerca volvulus Poor gastrulation protein homolog 0.0014 0.0031 0.0178
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0128 0.1277 0.1277
Brugia malayi metabotropic glutamate receptor type 2 0.0041 0.0327 0.0327
Echinococcus granulosus roundabout 2 0.0034 0.0258 0.0258
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0317 0.0317
Onchocerca volvulus 0.0021 0.0116 0.0664
Loa Loa (eye worm) hypothetical protein 0.009 0.0867 0.0867
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0086 0.0086
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0063 0.1244
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.1069 0.8837
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0021 0.0116 0.1075
Brugia malayi Dopamine receptor protein 1 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0063 0.0055
Echinococcus granulosus g protein coupled receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0317 0.0317
Onchocerca volvulus 0.0036 0.0279 0.1599
Brugia malayi hypoxia-induced factor 1 0.0152 0.1538 0.1538
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0453 0.1666
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0061 0.0549 0.0548
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0063 0.0055
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.1078 0.107
Leishmania major protein kinase, putative 0.0014 0.0038 0.0029
Echinococcus multilocularis growth factor receptor bound protein 2 0.0021 0.0112 0.0112
Echinococcus multilocularis mitogen activated protein kinase 11 0.0128 0.1277 0.1277
Echinococcus multilocularis mitogen activated protein kinase 14 0.0128 0.1277 0.1277
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0022 0.0082
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0128 0.1277 0.127
Echinococcus multilocularis hemicentin 1 0.0013 0.0028 0.0028
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0086 0.0086
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0289 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0012 0.0015 0.0015
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0018 0.0082 0.0082
Brugia malayi jmjC domain containing protein 0.0016 0.0056 0.0056
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0086 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus multilocularis netrin receptor unc 5 0.0021 0.0116 0.0116
Brugia malayi protein-tyrosine kinase 0.0051 0.0436 0.0436
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0026 0.0026
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0076 0.0708 0.0708
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase Blk 0.0051 0.0436 0.0436
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0056 0.0056
Echinococcus granulosus neuropeptide receptor 0.0019 0.0086 0.0086
Toxoplasma gondii fructose-bisphospatase II 0.093 1 1
Echinococcus granulosus death domain containing protein 0.0015 0.0041 0.0041
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0118 0.0433
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0086 0.0086
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0086 0.0084
Brugia malayi Tyrosine-protein kinase abl-1 0.0111 0.1095 0.1095
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0254 0.2642 0.2641
Plasmodium falciparum thioredoxin reductase 0.0048 0.0403 1
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0548 0.0546
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0056 0.0056
Trypanosoma brucei fructose-1,6-bisphosphatase 0.093 1 1
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0063 0.0055
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Brugia malayi putative neuropeptide receptor 0.0019 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0171 0.1745 0.1744
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0086 0.0086
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0113 0.0113
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0086 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.1069 0.8837
Onchocerca volvulus 0.0019 0.0086 0.0491
Schistosoma mansoni neuroglian 0.0013 0.0028 0.0027
Brugia malayi hypothetical protein 0.0021 0.0116 0.0116
Echinococcus multilocularis metabotropic glutamate receptor 2 0.007 0.0646 0.0646
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0015 0.0007
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0086 0.0086
Echinococcus multilocularis lamin 0.0027 0.018 0.018
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Schistosoma mansoni tyrosine kinase 0.0032 0.0229 0.0227
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0086 0.0086
Echinococcus granulosus lachesin 0.0013 0.0028 0.0028
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.007 0.007
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Schistosoma mansoni lipoxygenase 0.0103 0.1006 0.1005
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi jmjC domain containing protein 0.0016 0.0056 0.0056
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0063
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0453 0.0453
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0061 0.0549 0.0549
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0057 0.0057
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0086 0.0491
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0063 0.0055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0117 0.0117
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.1195 0.1195
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0028 0.0028
Brugia malayi hypothetical protein 0.004 0.0317 0.0317
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Echinococcus multilocularis N chimaerin 0.0018 0.0082 0.0082
Entamoeba histolytica protein kinase, putative 0.004 0.032 0.2973
Onchocerca volvulus 0.0019 0.0086 0.0491
Schistosoma mansoni loxhd1 0.004 0.0317 0.0315
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0548 0.0548
Brugia malayi jmjC domain containing protein 0.0016 0.0056 0.0056
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0038 0.0029
Leishmania major trypanothione reductase 0.0048 0.0403 0.0395
Echinococcus multilocularis c src tyrosine kinase 0.0032 0.0229 0.0229
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0013 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0021 0.0116 0.0114
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0514 0.0514
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0086 0.0086
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0063 0.0048
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0289 0.2684
Plasmodium falciparum thioredoxin reductase 0.0017 0.0063 0.1244
Brugia malayi Furin-like cysteine rich region family protein 0.078 0.837 0.837
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1078 1
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0022 0.0082
Echinococcus granulosus tyrosine protein kinase Src64B 0.0061 0.0549 0.0549
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0063 0.0063
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.1078 0.8918
Schistosoma mansoni metabotropic glutamate receptor 0.007 0.0646 0.0644
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0086 0.0086
Echinococcus granulosus netrin receptor unc 5 0.0021 0.0116 0.0116
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0022 0.0082
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0247 0.1904
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0022 0.0022
Echinococcus granulosus contactin 0.0013 0.0028 0.0028
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0042 0.0042
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Brugia malayi Sex muscle abnormal protein 5 0.0021 0.0112 0.0112
Schistosoma mansoni hypothetical protein 0.0171 0.1745 0.1744
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0032 0.0229 0.0227
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0063 0.0055
Brugia malayi hypothetical protein 0.0165 0.1677 0.1677
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0021 0.0112 0.0112
Brugia malayi Inositol-1 0.0037 0.0289 0.0289
Toxoplasma gondii fructose-bisphospatase I 0.0346 0.3646 0.3636
Schistosoma mansoni neuropeptide receptor 0.0019 0.0086 0.0084
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0086 0.0084
Schistosoma mansoni rab6-interacting 0.004 0.0317 0.0315
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0009 0.008
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0086 0.0086
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.1201 1
Schistosoma mansoni septate junction protein 0.0013 0.0028 0.0027
Brugia malayi PAS domain containing protein 0.0049 0.0418 0.0418
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0015 0.0043 0.0043
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Loa Loa (eye worm) TK protein kinase 0.0017 0.007 0.007
Brugia malayi hypothetical protein 0.0021 0.0113 0.0113
Toxoplasma gondii thioredoxin reductase 0.0048 0.0403 0.0388
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0206 0.0757
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0015 0.0007
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0453 0.1666
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0019 0.0086 0.049
Echinococcus granulosus tyrosine protein kinase otk 0.0013 0.0028 0.0028
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0289 0.0289
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0086 0.0084
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0089 0.1913
Loa Loa (eye worm) hypothetical protein 0.0165 0.1677 0.1677
Schistosoma mansoni neuropeptide receptor 0.0019 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0056 0.0054
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0206 0.1406
Schistosoma mansoni cell adhesion molecule 0.0013 0.0028 0.0027
Schistosoma mansoni histamine h1 receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis raf serine:threonine protein kinase 0.0229 0.2369 0.2369
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Plasmodium falciparum glutathione reductase 0.0048 0.0403 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0086 0.0086
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0206 0.4922
Schistosoma mansoni protein kinase 0.0019 0.0086 0.0084
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0086 0.0086
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0082 0.0081
Loa Loa (eye worm) TK/ABL protein kinase 0.023 0.2382 0.2382
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.8794 0.8794
Brugia malayi Cytochrome P450 family protein 0.0016 0.0057 0.0057
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0422 0.4475 0.4475
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0305 0.0305
Schistosoma mansoni tyrosine kinase 0.0019 0.0086 0.0084
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) SRC-1 0.0061 0.0549 0.0549
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0022 0.0022
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine kinase 0.0021 0.0116 0.0116
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0261 0.2721 0.2721
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0175 0.1786 0.1786
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Echinococcus granulosus g protein coupled receptor 0.0019 0.0086 0.0086
Brugia malayi 6-phosphofructokinase 0.011 0.1078 0.1078
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0062
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi RE15519p 0.0019 0.0086 0.0086
Loa Loa (eye worm) phosphofructokinase 0.011 0.1078 0.1078
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0086 0.0086
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0027 0.0174 0.0174
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0206 0.0191
Schistosoma mansoni biogenic amine receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis GPCR, family 3, C terminal 0.0014 0.0031 0.0031
Echinococcus granulosus mitogen activated protein kinase 14 0.0128 0.1277 0.1277
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0032 0.0229 0.0229
Onchocerca volvulus 0.0019 0.0086 0.0491
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.078 0.837 0.837
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0453 0.0445
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0086 0.0086
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0063 0.0059
Schistosoma mansoni hypothetical protein 0.0019 0.0086 0.0084
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0453 0.0445
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Schistosoma mansoni lamin 0.0027 0.018 0.0178
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0021 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0015 0.0041 0.004
Schistosoma mansoni inositol monophosphatase 0.0037 0.0289 0.0288
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi G-protein coupled receptor 0.0019 0.0086 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0086 0.0084
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0082 0.0081
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0128 0.1277 0.127
Onchocerca volvulus 0.0019 0.0086 0.0491
Brugia malayi ORL1-like opioid receptor 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0019 0.0086 0.0491
Onchocerca volvulus 0.0019 0.0086 0.0491
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0057 0.0049
Echinococcus granulosus microtubule associated protein 2 0.0697 0.7467 0.7467
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0453 1
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus serotonin receptor 0.0019 0.0086 0.0086
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0014 0.0031 0.0031
Schistosoma mansoni growth factor receptor-bound protein 0.0021 0.0112 0.0111
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0453 0.0453
Loa Loa (eye worm) hypothetical protein 0.0015 0.0043 0.0043
Onchocerca volvulus 0.004 0.0317 0.1814
Schistosoma mansoni hypothetical protein 0.0413 0.4378 0.4377
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0206 1
Schistosoma mansoni hypothetical protein 0.0019 0.0086 0.0084
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0063 0.0233
Schistosoma mansoni tyrosine kinase 0.0422 0.4475 0.4474
Brugia malayi AKH receptor 0.0019 0.0086 0.0086
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0206 0.4922
Plasmodium vivax glutathione reductase, putative 0.0048 0.0403 1
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0055
Loa Loa (eye worm) hypothetical protein 0.0103 0.1004 0.1004
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0317 0.761
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0453 0.0445
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) raf kinase 0.0218 0.2253 0.2253
Brugia malayi Serotonin receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis epidermal growth factor receptor 0.078 0.837 0.837
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0514 0.4472
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0086 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1078 0.3961
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0063 0.1244
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi SRC-1 0.0061 0.0549 0.0549
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.1201 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Brugia malayi G-protein coupled receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.093 1 1
Onchocerca volvulus 0.0021 0.0116 0.0664
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0086 0.0086
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0317 0.0317
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0057 0.0057
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0038 0.0029
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Schistosoma mansoni tyrosine kinase 0.0021 0.0117 0.0116
Echinococcus granulosus metabotropic glutamate receptor 5 0.0103 0.1004 0.1004
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0086 0.0086
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0118 0.0118
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0021 0.0116 0.0116
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0028 0.0188 0.0188
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.018 0.018
Schistosoma mansoni biogenic amine receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0086 0.0086
Echinococcus granulosus geminin 0.0171 0.1745 0.1745
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0086 0.0086
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis cpg binding protein 0.0031 0.0217 0.0217
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Brugia malayi neuropeptide F receptor 0.0019 0.0086 0.0086
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0289 0.0281
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0086 0.0086
Echinococcus multilocularis roundabout 2 0.0013 0.0028 0.0028
Leishmania major hypothetical protein, conserved 0.0016 0.0056 0.0047
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0289 0.2272
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus allatostatin A receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0086 0.0086
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0693 0.0693
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0188
Schistosoma mansoni tyrosine kinase 0.0411 0.4358 0.4358
Echinococcus multilocularis tyrosine protein kinase otk 0.0013 0.0028 0.0028
Schistosoma mansoni fructose-16-bisphosphatase-related 0.093 1 1
Onchocerca volvulus 0.0019 0.0086 0.049
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0134 0.1338 0.1338
Schistosoma mansoni nephrin 0.0013 0.0028 0.0027
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0057 0.0049
Echinococcus granulosus epidermal growth factor receptor 0.0422 0.4475 0.4475
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus epidermal growth factor receptor 0.078 0.837 0.837
Echinococcus multilocularis sex peptide receptor 0.0019 0.0086 0.0086
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0206 0.4545
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni myosin xvIII 0.0019 0.0086 0.0084
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0206 0.0191
Echinococcus granulosus hemicentin 1 0.0013 0.0028 0.0028
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0086 0.0086
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni roundabout 0.0013 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.007 0.007
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0086 0.0086
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0261 0.2721 0.2721
Plasmodium vivax JmjC domain containing protein 0.0016 0.0056 0.0382
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0026 0.0026
Echinococcus granulosus N chimaerin 0.0018 0.0082 0.0082
Echinococcus granulosus fructose 16 bisphosphatase 1 0.093 1 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0086 0.0086
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0056 0.0056
Brugia malayi Prion-like- 0.0013 0.0028 0.0028
Brugia malayi Dopamine receptor 0.0019 0.0086 0.0086
Schistosoma mansoni opsin-like receptor 0.0019 0.0086 0.0084
Brugia malayi Guanylyl cyclase protein 23 0.0019 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0422 0.4475 0.4474
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0548 0.0546
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0086 0.0086
Echinococcus granulosus phd:f box containing protein 0.0016 0.0056 0.0056
Brugia malayi MH2 domain containing protein 0.0121 0.1195 0.1195
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus granulosus insulin receptor 0.0254 0.2642 0.2642
Onchocerca volvulus 0.0019 0.0086 0.0491
Brugia malayi CXXC zinc finger family protein 0.0029 0.0199 0.0199
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.2369 0.2368
Echinococcus granulosus lamin dm0 0.0027 0.018 0.018
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0009 0.0032
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Echinococcus granulosus g protein coupled receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0017 0.007 0.007
Echinococcus granulosus neuroglian 0.0028 0.0183 0.0183
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0061 0.0549 0.0549
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.032 0.032
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0086 0.0086
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0086 0.0086
Brugia malayi Protein kinase domain containing protein 0.0419 0.444 0.444
Schistosoma mansoni tyrosine kinase 0.0411 0.4358 0.4358
Schistosoma mansoni neuropeptide receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0254 0.2642 0.2642
Loa Loa (eye worm) hypothetical protein 0.004 0.0317 0.0317
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0086 0.0086
Brugia malayi Tyrosine-protein kinase abl-1 0.0129 0.1283 0.1283
Echinococcus multilocularis tyrosine protein kinase shark 0.0021 0.0117 0.0117
Brugia malayi SH2 domain containing protein 0.0021 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0086 0.0086
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0086 0.0086
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0086 0.0084
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.007 0.007
Schistosoma mansoni cpg binding protein 0.0029 0.0199 0.0198
Onchocerca volvulus 0.0012 0.0012 0.0066
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0016 0.0016
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0453 0.0445
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0074 0.0074
Schistosoma mansoni 6-phosphofructokinase 0.011 0.1078 0.1077
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0453 0.0445
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0028 0.0027
Brugia malayi jmjC domain containing protein 0.0061 0.0548 0.0548
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0026 0.0026
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0018 0.0082 0.0082
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.093 1 1
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Schistosoma mansoni opsin-like receptor 0.0019 0.0086 0.0084
Trypanosoma brucei protein kinase, putative 0.0052 0.0453 0.0445
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0453 0.0452
Echinococcus multilocularis tyrosine protein kinase HCK 0.004 0.032 0.032
Entamoeba histolytica protein kinase domain containing protein 0.0012 0.0015 0.0141
Echinococcus granulosus peroxidasin 0.0013 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0061 0.0549 0.0548
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0056 0.0041
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0061 0.0549 0.0549
Schistosoma mansoni hypothetical protein 0.0019 0.0086 0.0084
Leishmania major ATP-dependent phosphofructokinase 0.011 0.1078 0.107
Echinococcus granulosus c src tyrosine kinase 0.0032 0.0229 0.0229
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0086 0.0086
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Schistosoma mansoni nephrin 0.0028 0.0183 0.0182
Brugia malayi MAP kinase sur-1 0.0052 0.0453 0.0453
Schistosoma mansoni tyrosine kinase 0.0019 0.0086 0.0084
Schistosoma mansoni tyrosine kinase 0.0024 0.0145 0.0143
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus granulosus tyrosine protein kinase ABL1 0.023 0.2382 0.2382
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.1078 1
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Schistosoma mansoni hypothetical protein 0.004 0.0317 0.0315
Echinococcus multilocularis NCK adaptor protein 0.0021 0.0112 0.0112
Echinococcus granulosus metabotropic glutamate receptor 2 0.007 0.0646 0.0646
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0086 0.0084
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0063 0.0596
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0056 0.0056
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0419 0.444 0.444
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0086 0.0086
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0289 0.1063
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1078 0.3961
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1078 1
Echinococcus multilocularis musashi 0.0027 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.018
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0043 0.0041
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0086 0.0086
Echinococcus granulosus Immunoglobulin 0.0021 0.0113 0.0113
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Echinococcus granulosus somatostatin receptor 0.0019 0.0086 0.0086
Leishmania major protein kinase, putative 0.0012 0.0015 0.0007
Loa Loa (eye worm) glutamate receptor 0.0084 0.0793 0.0793
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0063 0.0059
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0056 0.0047
Brugia malayi neuropeptide F receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.053 0.053
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0453 0.1666
Echinococcus multilocularis hemicentin 1 0.0013 0.0028 0.0028
Echinococcus granulosus NCK adaptor protein 0.0021 0.0112 0.0112
Echinococcus multilocularis lachesin 0.0013 0.0028 0.0028
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0514 0.0514
Echinococcus multilocularis somatostatin receptor 0.0019 0.0086 0.0086
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0086 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0514 0.4472
Brugia malayi Uncoordinated protein 44 0.0015 0.0041 0.0041
Trypanosoma brucei trypanothione reductase 0.0048 0.0403 0.0395
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0086 0.0086
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0022 0.0014
Brugia malayi Serotonin receptor 0.0019 0.0086 0.0086
Onchocerca volvulus Glucosylceramidase homolog 0.0171 0.1745 1
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.004 0.0025
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Echinococcus granulosus defective proboscis extension response 0.0021 0.0113 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0254 0.2642 0.2642
Echinococcus granulosus receptor type guanylyl cyclase 0.0019 0.0086 0.0086
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0086 0.0086
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0086 0.0086
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.1201 1
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0514 0.3959
Onchocerca volvulus 0.0013 0.0022 0.0128
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0453 0.0445
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0082 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0113 0.0113
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0061 0.0549 0.0549
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.1538 0.1538
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.0346 0.3646 0.364
Echinococcus granulosus raf serine:threonine protein kinase 0.0229 0.2369 0.2369
Loa Loa (eye worm) glutathione reductase 0.0048 0.0403 0.0403
Schistosoma mansoni titin 0.0013 0.0028 0.0027
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0021 0.0116 0.0664
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0028 0.0028
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0086 0.0086
Schistosoma mansoni netrin receptor unc5 0.0021 0.0116 0.0115
Loa Loa (eye worm) hypothetical protein 0.004 0.0317 0.0317
Echinococcus granulosus single minded 2 0.0036 0.0279 0.0279
Echinococcus granulosus neuropeptide receptor 0.0019 0.0086 0.0086
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0086 0.0086
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0056 0.0047
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0086 0.0084
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0095 0.0918 0.0917
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0206 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0086 0.0086
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0022 0.0082
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0063 0.1399
Echinococcus granulosus tyrosine protein kinase HCK 0.004 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.1078 0.107
Schistosoma mansoni vav2 0.0018 0.0082 0.0081
Brugia malayi Protein kinase domain containing protein 0.0254 0.2642 0.2642
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus multilocularis roundabout 2 0.0034 0.0258 0.0258
Echinococcus multilocularis 0.024 0.2489 0.2489
Schistosoma mansoni intermediate filament proteins 0.0027 0.018 0.0178
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Echinococcus multilocularis geminin 0.0171 0.1745 0.1745
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0403 0.0403
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0063 0.0055
Brugia malayi Death domain containing protein 0.0015 0.0041 0.0041
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0346 0.3646 0.364
Echinococcus granulosus RUN 0.004 0.0317 0.0317
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.007 0.007
Echinococcus multilocularis microtubule associated protein 2 0.0697 0.7467 0.7467
Schistosoma mansoni cpg binding protein 0.0031 0.0217 0.0216
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0086 0.0086
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0021 0.0113 0.0112
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis tyrosine kinase 0.0019 0.0086 0.0086
Schistosoma mansoni lipoxygenase 0.0175 0.1786 0.1785
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0086 0.0086
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Brugia malayi intermediate filament protein 0.0027 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0317 0.0317
Echinococcus multilocularis neuroglian 0.0028 0.0183 0.0183
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus growth factor receptor bound protein 2 0.0021 0.0112 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Loa Loa (eye worm) TK protein kinase 0.0051 0.0436 0.0436
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0056 0.0056
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Loa Loa (eye worm) hypothetical protein 0.0021 0.0112 0.0112
Onchocerca volvulus Tyrosine kinase homolog 0.0017 0.007 0.0399
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.053 0.053
Echinococcus granulosus neuroglian 0.0013 0.0028 0.0028
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0063
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0514 0.0506
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0247 0.1611
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0057 0.0057
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.1201 1
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0061 0.0549 0.0549
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0086 0.0084
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0038 0.0029
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0028 0.0028
Leishmania major protein kinase, putative 0.0014 0.0038 0.0029
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0289 0.0289
Echinococcus granulosus activin receptor type 0.0012 0.0015 0.0015
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0013 0.0028 0.0028
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0041 0.0041
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0056 0.0041
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0063 0.0596
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni cell adhesion molecule 0.0013 0.0028 0.0027
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0056 0.0054
Echinococcus multilocularis Immunoglobulin 0.0021 0.0113 0.0113
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0453 0.0445
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0061 0.0549 0.0549
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0086 0.0086
Brugia malayi Dopamine receptor protein 2 0.0019 0.0086 0.0086
Schistosoma mansoni lamin 0.0027 0.018 0.0178
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0018 0.0082 0.0082
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0056 0.0056
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0199 0.0199
Schistosoma mansoni biogenic amine receptor 0.0019 0.0086 0.0084
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0013 0.0028 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0346 0.3646 0.364
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0086 0.0086
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0056 0.1045
Brugia malayi Protein kinase domain containing protein 0.0016 0.0057 0.0057
Echinococcus multilocularis tyrosine protein kinase Blk 0.0051 0.0436 0.0436
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0086 0.0086
Leishmania major cytochrome p450-like protein 0.0016 0.0057 0.0049
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0317 0.7775
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0279 0.0279
Echinococcus granulosus Ankyrin 0.0015 0.0043 0.0043
Schistosoma mansoni adenoreceptor 0.0019 0.0086 0.0084
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0086 0.0084
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0022 0.0022
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0012 0.0015 0.0015
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0086 0.0086
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.1078 0.8956
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0289 0.1063
Schistosoma mansoni cell adhesion molecule 0.0028 0.0188 0.0187
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0032 0.0229 0.0229
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0022 0.0082
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.1069 0.8878
Brugia malayi G protein-coupled receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0086 0.0086
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0013 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0019 0.0086 0.0491
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0317 0.0317
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0086 0.0086
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0056 0.0047
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Echinococcus multilocularis receptor type guanylyl cyclase 0.0019 0.0086 0.0086
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.093 1 1
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0317 0.0317
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni adapter molecule crk 0.0021 0.0112 0.0111
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.053 0.053
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus granulosus tyrosine protein kinase Srms 0.0021 0.0116 0.0116
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0453 0.0453
Loa Loa (eye worm) TK/INSR protein kinase 0.0254 0.2642 0.2642
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0022 0.0082
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0021 0.0113 0.0113
Schistosoma mansoni inositol monophosphatase 0.0037 0.0289 0.0288
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0206 0.4546
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0553 0.0552
Brugia malayi larval opioid receptor 0.0019 0.0086 0.0086
Schistosoma mansoni metabotropic glutamate receptor 0.0041 0.0327 0.0326
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.