Detailed information for compound 764321

Basic information

Technical information
  • TDR Targets ID: 764321
  • Name: 2-[4-(3-nitrophenyl)-1-oxophthalazin-2-yl]-N- propylacetamide
  • MW: 366.371 | Formula: C19H18N4O4
  • H donors: 1 H acceptors: 4 LogP: 2.93 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCNC(=O)Cn1nc(c2cccc(c2)[N+](=O)[O-])c2c(c1=O)cccc2
  • InChi: 1S/C19H18N4O4/c1-2-10-20-17(24)12-22-19(25)16-9-4-3-8-15(16)18(21-22)13-6-5-7-14(11-13)23(26)27/h3-9,11H,2,10,12H2,1H3,(H,20,24)
  • InChiKey: DLWWQNCETLSUFD-UHFFFAOYSA-N  

Network

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Synonyms

  • 2-[4-(3-nitrophenyl)-1-oxo-phthalazin-2-yl]-N-propyl-acetamide
  • 2-[4-(3-nitrophenyl)-1-oxo-2-phthalazinyl]-N-propylacetamide
  • 2-[1-keto-4-(3-nitrophenyl)phthalazin-2-yl]-N-propyl-acetamide
  • 2-[4-(3-nitrophenyl)-1-oxo-phthalazin-2-yl]-N-propyl-ethanamide
  • STOCK5S-13710
  • ZINC01887429

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni septate junction protein 0.0013 0.0028 0.0027
Echinococcus multilocularis N chimaerin 0.0018 0.0082 0.0082
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Schistosoma mansoni cell adhesion molecule 0.0013 0.0028 0.0027
Brugia malayi metabotropic glutamate receptor type 2 0.0041 0.0327 0.0327
Echinococcus granulosus g-protein coupled receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis lysine specific demethylase 6a 0.0016 0.0056 0.0056
Schistosoma mansoni hypothetical protein 0.0019 0.0086 0.0084
Echinococcus granulosus phd:f box containing protein 0.0016 0.0056 0.0056
Echinococcus multilocularis Aryl hydrocarbon receptor nuclear 0.0013 0.0022 0.0022
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0057 0.0057
Echinococcus multilocularis 6 phosphofructokinase 0.011 0.1078 0.1078
Echinococcus granulosus activin receptor type 0.0012 0.0015 0.0015
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1078 1
Echinococcus multilocularis allatostatin A receptor 0.0019 0.0086 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0453 0.1666
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0038 0.0029
Brugia malayi jmjC domain containing protein 0.0016 0.0056 0.0056
Echinococcus granulosus GPCR family 3 C terminal 0.0014 0.0031 0.0031
Entamoeba histolytica protein kinase domain containing protein 0.0012 0.0015 0.0141
Brugia malayi Guanylyl cyclase protein 23 0.0019 0.0086 0.0086
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.018 0.018
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1078 0.3961
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0048 0.0403 0.2985
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0028 0.0028
Echinococcus granulosus neuroglian 0.0013 0.0028 0.0028
Echinococcus multilocularis c src tyrosine kinase 0.0032 0.0229 0.0229
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0022 0.0014
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1078 1
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1078 0.3961
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0017 0.007 0.007
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0103 0.1004 0.1004
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0037 0.0289 0.2272
Echinococcus multilocularis tyrosine protein kinase Srms 0.0051 0.0436 0.0436
Echinococcus multilocularis hemicentin 1 0.0013 0.0028 0.0028
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0086 0.0084
Brugia malayi Thioredoxin reductase 0.0048 0.0403 0.0403
Schistosoma mansoni neuroglian 0.0013 0.0028 0.0027
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0289 0.0281
Brugia malayi hypoxia-induced factor 1 0.0152 0.1538 0.1538
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) aryl Hydrocarbon receptor Associated protein family member 0.0013 0.0022 0.0022
Onchocerca volvulus 0.0012 0.0012 0.0066
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0017 0.0063 0.0055
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0128 0.1277 0.127
Schistosoma mansoni blooms syndrome DNA helicase 0.0017 0.0069 0.0067
Onchocerca volvulus 0.0019 0.0086 0.0491
Onchocerca volvulus 0.0021 0.0116 0.0664
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0037 0.0289 0.2684
Echinococcus multilocularis tyrosine kinase 0.0019 0.0086 0.0086
Echinococcus multilocularis geminin 0.0171 0.1745 0.1745
Echinococcus granulosus microtubule associated protein 2 0.0697 0.7467 0.7467
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0453 0.0445
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0086 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0453 0.0452
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0082 0.0081
Echinococcus granulosus raf serine:threonine protein kinase 0.0229 0.2369 0.2369
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0453 0.0453
Loa Loa (eye worm) melatonin receptor type 1A 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase ABL1 0.023 0.2382 0.2382
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Schistosoma mansoni tyrosine kinase 0.0024 0.0145 0.0143
Brugia malayi MAP kinase sur-1 0.0052 0.0453 0.0453
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni cell adhesion molecule 0.0013 0.0028 0.0027
Echinococcus multilocularis tyrosine protein kinase lyn lyn a protein tyrosine kinase lymphocyte specific protein tyrosine kinase 0.0061 0.0549 0.0549
Brugia malayi hypothetical protein 0.004 0.0317 0.0317
Schistosoma mansoni cpg binding protein 0.0031 0.0217 0.0216
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0057 0.0049
Onchocerca volvulus 0.0019 0.0086 0.0491
Loa Loa (eye worm) hypothetical protein 0.009 0.0867 0.0867
Schistosoma mansoni titin 0.0013 0.0028 0.0027
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Toxoplasma gondii phosphofructokinase PFKII 0.003 0.0206 0.0191
Brugia malayi Fibronectin type III domain containing protein 0.0021 0.0113 0.0113
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0086 0.0086
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0199 0.0199
Brugia malayi G-protein coupled receptor 0.0019 0.0086 0.0086
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0317 0.0317
Brugia malayi Raf kinase 0.0221 0.2286 0.2286
Loa Loa (eye worm) TK/ABL protein kinase 0.023 0.2382 0.2382
Loa Loa (eye worm) TKL/RAF/RAF protein kinase 0.0134 0.1338 0.1338
Echinococcus granulosus 7tm_1 domain containing protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0021 0.0117 0.0117
Echinococcus granulosus tyrosine protein kinase Blk 0.0051 0.0436 0.0436
Echinococcus granulosus contactin 0.0013 0.0028 0.0028
Echinococcus granulosus peptide allatostatin:somatostatin 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0021 0.0116 0.0664
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0042 0.0042
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0086 0.0084
Schistosoma mansoni growth factor receptor-bound protein 0.0021 0.0112 0.0111
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0109 0.1069 0.8837
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Brugia malayi Protein kinase domain containing protein 0.0419 0.444 0.444
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0062
Leishmania major hypothetical protein, conserved 0.0016 0.0056 0.0047
Echinococcus multilocularis mitogen activated protein kinase 11 0.0128 0.1277 0.1277
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0453 0.0445
Schistosoma mansoni hypothetical protein 0.0413 0.4378 0.4377
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0086 0.0086
Schistosoma mansoni fructose-16-bisphosphatase-related 0.093 1 1
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0429 0.455 0.455
Leishmania major 0.093 1 1
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0013 0.0022 0.0022
Schistosoma mansoni neuropeptide receptor 0.0019 0.0086 0.0084
Loa Loa (eye worm) TYRA-2 protein 0.0019 0.0086 0.0086
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Echinococcus granulosus hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni nephrin 0.0013 0.0028 0.0027
Echinococcus multilocularis peroxidasin 0.0013 0.0028 0.0028
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Brugia malayi 6-phosphofructokinase 0.011 0.1078 0.1078
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0021 0.0113 0.0112
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Onchocerca volvulus 0.0019 0.0086 0.0491
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Schistosoma mansoni lamin 0.0027 0.018 0.0178
Brugia malayi jmjC domain containing protein 0.0016 0.0056 0.0056
Echinococcus granulosus N chimaerin 0.0018 0.0082 0.0082
Schistosoma mansoni histamine h1 receptor 0.0019 0.0086 0.0084
Brugia malayi putative neuropeptide receptor NPR1 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Schistosoma mansoni adenoreceptor 0.0019 0.0086 0.0084
Onchocerca volvulus Glucosylceramidase homolog 0.0171 0.1745 1
Echinococcus multilocularis tyrosine protein kinase transmembrane receptor 0.0017 0.007 0.007
Schistosoma mansoni 6-phosphofructokinase 0.011 0.1078 0.1077
Echinococcus granulosus defective proboscis extension response 0.0021 0.0113 0.0113
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0022 0.0082
Echinococcus granulosus RUN 0.004 0.0317 0.0317
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0056 0.0056
Onchocerca volvulus 0.004 0.0317 0.1814
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0422 0.4475 0.4474
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0019 0.0086 0.0084
Schistosoma mansoni phd/f-box containing protein 0.0016 0.0056 0.0054
Trichomonas vaginalis adenylate cyclase, type VII, putative 0.0013 0.0022 0.0082
Echinococcus multilocularis mitogen activated protein kinase 14 0.0128 0.1277 0.1277
Schistosoma mansoni proto-oncogene tyrosine-protein kinase src 0.0032 0.0229 0.0227
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0022 0.0082
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0086 0.0086
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Echinococcus multilocularis bloom syndrome protein 0.0022 0.0118 0.0118
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Brugia malayi SH2 domain containing protein 0.0021 0.0116 0.0116
Echinococcus multilocularis dro:myosuppressin receptor 0.0019 0.0086 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Echinococcus multilocularis guanine nucleotide exchange factor VAV2 0.0018 0.0082 0.0082
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Toxoplasma gondii fructose-bisphospatase II 0.093 1 1
Onchocerca volvulus 0.0036 0.0279 0.1599
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis epidermal growth factor receptor 0.0422 0.4475 0.4475
Echinococcus granulosus neuropeptide receptor 0.0019 0.0086 0.0086
Echinococcus granulosus metabotropic glutamate receptor 2 0.007 0.0646 0.0646
Brugia malayi 6-phosphofructokinase 0.011 0.1078 0.1078
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0033 0.0247 0.1904
Loa Loa (eye worm) hypothetical protein 0.0028 0.0188 0.0188
Brugia malayi Bloom's syndrome protein homolog 0.0022 0.0118 0.0118
Schistosoma mansoni chimerin-related rho-gtpase-activating protein 0.0018 0.0082 0.0081
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0453 0.0445
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Echinococcus granulosus tyrosine protein kinase Srms 0.0021 0.0116 0.0116
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0033 0.0247 0.1611
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0038 0.0029
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0022 0.0082
Echinococcus multilocularis neuroglian 0.0013 0.0028 0.0028
Echinococcus multilocularis Immunoglobulin 0.0021 0.0113 0.0113
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0481 0.0467
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.003 0.0206 0.1912
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0019 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0019 0.0086 0.0086
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0109 0.1069 0.8837
Echinococcus multilocularis tyrosine protein kinase Blk 0.0051 0.0436 0.0436
Brugia malayi jmjC domain containing protein 0.0016 0.0056 0.0056
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0109 0.1069 0.8837
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus multilocularis tyrosine kinase 0.0021 0.0116 0.0116
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0037 0.0289 1
Loa Loa (eye worm) intermediate filament protein 0.0027 0.018 0.018
Echinococcus granulosus allatostatin A receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Echinococcus multilocularis transfer RNA-Lys 0.0036 0.0279 0.0279
Onchocerca volvulus Neuropeptide F receptor homolog 0.0019 0.0086 0.0491
Echinococcus granulosus lamin 0.0027 0.018 0.018
Brugia malayi PAS domain containing protein 0.0049 0.0418 0.0418
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0121 0.1201 1
Brugia malayi hypothetical protein 0.0021 0.0116 0.0116
Schistosoma mansoni 6-phosphofructokinase 0.011 0.1078 0.1077
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0058 0.0514 0.0506
Loa Loa (eye worm) hypothetical protein 0.004 0.0317 0.0317
Echinococcus granulosus c src tyrosine kinase 0.0032 0.0229 0.0229
Loa Loa (eye worm) jmjC domain-containing protein 0.0016 0.0056 0.0056
Echinococcus granulosus somatostatin receptor 0.0019 0.0086 0.0086
Schistosoma mansoni septate junction protein 0.0013 0.0028 0.0027
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0116 0.0116
Echinococcus multilocularis orexin receptor type 2 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase shark 0.0021 0.0117 0.0117
Schistosoma mansoni hypothetical protein 0.0171 0.1745 0.1744
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0289 0.0281
Echinococcus multilocularis Polycystic kidney disease protein 0.004 0.0317 0.0317
Loa Loa (eye worm) camk/mapkapk/mnk protein kinase 0.0419 0.444 0.444
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0017 0.0063 0.1244
Echinococcus granulosus epidermal growth factor receptor 0.0422 0.4475 0.4475
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0453 0.0445
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0019 0.0086 0.0086
Loa Loa (eye worm) glutathione reductase 0.0048 0.0403 0.0403
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Brugia malayi bHLH-PAS transcription factor 0.0036 0.0279 0.0279
Brugia malayi Tyrosine-protein kinase abl-1 0.0129 0.1283 0.1283
Echinococcus granulosus tyrosine protein kinase Fps85D 0.0021 0.0116 0.0116
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0121 0.1201 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Brugia malayi jmjC domain containing protein 0.0061 0.0548 0.0548
Echinococcus multilocularis dnaJ subfamily B 0.0413 0.4378 0.4378
Onchocerca volvulus 0.004 0.0317 0.1814
Echinococcus multilocularis tyrosine protein kinase Src42A 0.004 0.032 0.032
Schistosoma mansoni single-minded 0.0049 0.0418 0.0417
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0514 0.0514
Echinococcus granulosus thioredoxin glutathione reductase 0.0048 0.0403 0.0403
Echinococcus multilocularis RUN 0.004 0.0317 0.0317
Onchocerca volvulus 0.0019 0.0086 0.0491
Trichomonas vaginalis DNA helicase recq, putative 0.0012 0.0009 0.0032
Schistosoma mansoni tyrosine kinase 0.0019 0.0086 0.0084
Echinococcus multilocularis musashi 0.0027 0.018 0.018
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1078 0.3961
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0289 0.0281
Schistosoma mansoni cpg binding protein 0.0029 0.0199 0.0198
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) RecQ helicase 0.0022 0.0118 0.0118
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0453 0.0453
Onchocerca volvulus 0.0027 0.018 0.103
Echinococcus multilocularis growth factor receptor bound protein 2 0.0021 0.0112 0.0112
Loa Loa (eye worm) TK protein kinase 0.0017 0.007 0.007
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0017 0.0063 0.2238
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase Btk29A 0.0032 0.0229 0.0229
Echinococcus granulosus intermediate filament protein 0.0027 0.018 0.018
Schistosoma mansoni biogenic amine receptor 0.0019 0.0086 0.0084
Mycobacterium ulcerans putative regulatory protein 0.0036 0.0279 0.2172
Schistosoma mansoni alpha-1 adrenergic receptor 0.0019 0.0086 0.0084
Schistosoma mansoni microtubule-associated protein tau 0.0697 0.7467 0.7466
Onchocerca volvulus Atrial natriuretic peptide receptor 3 homolog 0.0019 0.0086 0.049
Echinococcus granulosus neuropeptide receptor 0.0019 0.0086 0.0086
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus neuropeptides capa receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0019 0.0086 0.0086
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0015 0.0007
Loa Loa (eye worm) glutamate receptor 0.0033 0.0241 0.0241
Echinococcus granulosus insulin receptor 0.0254 0.2642 0.2642
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.007 0.007
Onchocerca volvulus 0.0019 0.0086 0.0491
Brugia malayi hypothetical protein 0.004 0.0317 0.0317
Echinococcus granulosus tyrosine protein kinase Src42A 0.004 0.032 0.032
Schistosoma mansoni rab6-interacting 0.004 0.0317 0.0315
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0019 0.0086 0.0086
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0019 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0254 0.2642 0.2641
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0019 0.0086 0.0086
Echinococcus granulosus NCK adaptor protein 0.0021 0.0112 0.0112
Schistosoma mansoni cell adhesion molecule 0.0013 0.0028 0.0027
Schistosoma mansoni cell adhesion molecule 0.0028 0.0188 0.0187
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0086 0.0086
Echinococcus granulosus Ankyrin 0.0015 0.0043 0.0043
Loa Loa (eye worm) CMGC/MAPK/P38 protein kinase 0.0128 0.1277 0.1277
Echinococcus granulosus roundabout 2 0.0034 0.0258 0.0258
Brugia malayi hypothetical protein 0.0021 0.0113 0.0113
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0028 0.0028
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0021 0.0113 0.0113
Echinococcus multilocularis roundabout 2 0.0034 0.0258 0.0258
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0074 0.0693 0.0693
Brugia malayi Immunoglobulin I-set domain containing protein 0.0021 0.0113 0.0113
Schistosoma mansoni vesicular amine transporter 0.0021 0.0113 0.0112
Schistosoma mansoni tyrosine kinase 0.0411 0.4358 0.4358
Echinococcus granulosus g protein coupled receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0254 0.2642 0.2642
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0019 0.0089 0.1913
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0086 0.0086
Schistosoma mansoni polycystin 1-related 0.004 0.0317 0.0315
Brugia malayi Serotonin receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) MH2 domain-containing protein 0.0121 0.1195 0.1195
Schistosoma mansoni neurotracting/lsamp/neurotrimin/obcam related cell adhesion molecule 0.0013 0.0028 0.0027
Onchocerca volvulus 0.0021 0.0116 0.0664
Echinococcus multilocularis tyrosine protein kinase HCK 0.004 0.032 0.032
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0175 0.1786 0.1786
Plasmodium falciparum thioredoxin reductase 0.0048 0.0403 1
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Entamoeba histolytica protein kinase, putative 0.0012 0.0014 0.0134
Echinococcus multilocularis g-protein coupled receptor 0.0019 0.0086 0.0086
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Echinococcus multilocularis GPCR, family 3, C terminal 0.0014 0.0031 0.0031
Brugia malayi Uncoordinated protein 44 0.0015 0.0041 0.0041
Loa Loa (eye worm) fructose-1,6-bisphosphatase 0.093 1 1
Schistosoma mansoni tyrosine kinase 0.0219 0.2267 0.2266
Schistosoma mansoni ankyrin 23/unc44 0.0015 0.0041 0.004
Loa Loa (eye worm) hypothetical protein 0.0013 0.0021 0.0021
Echinococcus granulosus twitchin 0.0029 0.0198 0.0198
Schistosoma mansoni protein kinase 0.0012 0.0015 0.0014
Trichomonas vaginalis inositol monophosphatase, putative 0.0037 0.0289 0.1063
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0289 0.1063
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0015 0.0041 0.0041
Echinococcus granulosus aryl hydrocarbon receptor 0.0013 0.0022 0.0022
Echinococcus granulosus tyrosine protein kinase transmembrane receptor 0.0017 0.007 0.007
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0013 0.0028 0.0028
Echinococcus multilocularis somatostatin receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) transcription factor SMAD2 0.0121 0.1195 0.1195
Trypanosoma cruzi trypanothione reductase, putative 0.0017 0.0063 0.0055
Echinococcus granulosus roundabout 2 0.0013 0.0028 0.0028
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0086 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Echinococcus granulosus orexin receptor type 2 0.0019 0.0086 0.0086
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Echinococcus granulosus tyrosine kinase 0.0019 0.0086 0.0086
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0012 0.0016 0.0016
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Brugia malayi neuropeptide F receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0027 0.0174 0.0174
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0018 0.0074 0.0074
Giardia lamblia Kinase, NEK 0.0011 0.0001 0.003
Leishmania major PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0022 0.0014
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi glutathione reductase 0.0048 0.0403 0.0403
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.011 0.1078 0.8918
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0019 0.0086 0.0086
Schistosoma mansoni opsin-like receptor 0.0019 0.0086 0.0084
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Plasmodium vivax multidomain scavenger receptor, putative 0.004 0.0317 0.761
Echinococcus granulosus growth factor receptor bound protein 2 0.0021 0.0112 0.0112
Brugia malayi AKH receptor 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0015 0.0041 0.0041
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0026 0.0026
Brugia malayi Serotonin receptor 0.0019 0.0086 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0086 0.0086
Schistosoma mansoni hypothetical protein 0.0171 0.1745 0.1744
Brugia malayi intermediate filament protein 0.0027 0.018 0.018
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0086 0.0086
Echinococcus granulosus neuroglian 0.0028 0.0183 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Onchocerca volvulus Metabotropic glutamate receptor homolog 0.0014 0.0031 0.0178
Schistosoma mansoni cpg binding protein 0.0031 0.0217 0.0216
Loa Loa (eye worm) hypothetical protein 0.0034 0.0258 0.0258
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1846 0.6782
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.1078 0.1078
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0453 0.0453
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0017 0.0063 0.0055
Echinococcus multilocularis G-protein coupled receptor, putative 0.0019 0.0086 0.0086
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Schistosoma mansoni hypothetical protein 0.0019 0.0086 0.0084
Onchocerca volvulus 0.0019 0.0086 0.0491
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Echinococcus multilocularis dual specificity testis specific protein kinase 0.0012 0.0015 0.0015
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0013 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0086 0.0086
Schistosoma mansoni protein kinase 0.0019 0.0086 0.0084
Schistosoma mansoni tyrosine kinase 0.078 0.837 0.837
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0453 0.1666
Echinococcus granulosus mitogen activated protein kinase 14 0.0128 0.1277 0.1277
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0076 0.0708 0.0708
Trichomonas vaginalis guanylate cyclase, putative 0.0013 0.0022 0.0082
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0017 0.0063 0.0055
Schistosoma mansoni opsin-like receptor 0.0019 0.0086 0.0084
Schistosoma mansoni netrin receptor unc5 0.0021 0.0116 0.0115
Echinococcus granulosus serotonin receptor 0.0019 0.0086 0.0086
Brugia malayi Dopamine receptor protein 1 0.0019 0.0086 0.0086
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0019 0.0086 0.0084
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0422 0.4475 0.4475
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0086 0.0086
Echinococcus granulosus proto oncogene tyrosine protein kinase LCK 0.0061 0.0549 0.0549
Echinococcus multilocularis serotonin receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis mitogen activated protein kinase 11 0.0128 0.1277 0.1277
Loa Loa (eye worm) hypoxia-induced factor 1 0.0152 0.1538 0.1538
Echinococcus granulosus fmrfamide receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) glutamate receptor 0.0084 0.0793 0.0793
Echinococcus granulosus death domain containing protein 0.0015 0.0041 0.0041
Onchocerca volvulus Tyrosine kinase homolog 0.0017 0.007 0.0399
Echinococcus granulosus 6 phosphofructokinase 0.011 0.1078 0.1078
Entamoeba histolytica protein kinase, putative 0.004 0.032 0.2973
Echinococcus multilocularis fructose 1,6 bisphosphatase 1 0.093 1 1
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0086 0.0086
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0086 0.0086
Plasmodium vivax thioredoxin reductase, putative 0.0048 0.0403 1
Schistosoma mansoni neuropeptide receptor 0.0019 0.0086 0.0084
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Mycobacterium tuberculosis Probable reductase 0.0109 0.1069 0.8837
Loa Loa (eye worm) TK/KIN16 protein kinase 0.0039 0.0305 0.0305
Loa Loa (eye worm) hypothetical protein 0.0014 0.0031 0.0031
Echinococcus granulosus sex peptide receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0019 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus receptor type guanylyl cyclase 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0021 0.0116 0.0116
Brugia malayi Dopamine receptor protein 2 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0019 0.0086 0.0491
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni intermediate filament proteins 0.0027 0.018 0.0178
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0019 0.0086 0.0086
Echinococcus granulosus dnaJ subfamily B 0.0413 0.4378 0.4378
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0453 0.0453
Schistosoma mansoni adapter molecule crk 0.0021 0.0112 0.0111
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Toxoplasma gondii thioredoxin reductase 0.0048 0.0403 0.0388
Echinococcus multilocularis tyrosine protein kinase Src42A 0.0061 0.0549 0.0549
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) inositol-1 0.0037 0.0289 0.0289
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Toxoplasma gondii NADPH-glutathione reductase 0.0017 0.0063 0.0048
Echinococcus granulosus inositol monophosphatase 1 0.0037 0.0289 0.0289
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0453 0.0445
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Schistosoma mansoni metabotropic glutamate receptor 0.0041 0.0327 0.0326
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi jmjC domain containing protein 0.0059 0.053 0.053
Leishmania major protein kinase, putative 0.0012 0.0015 0.0007
Echinococcus multilocularis lysine specific demethylase 5A 0.0059 0.053 0.053
Trichomonas vaginalis glutathione reductase, putative 0.0017 0.0063 0.0233
Trichomonas vaginalis phosphofructokinase, putative 0.011 0.1078 0.3961
Giardia lamblia NADH oxidase lateral transfer candidate 0.0017 0.0063 0.1399
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0022 0.0082
Brugia malayi jmjC domain containing protein 0.0016 0.0056 0.0056
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0112 0.0112
Echinococcus multilocularis lamin dm0 0.0027 0.018 0.018
Plasmodium vivax glutathione reductase, putative 0.0048 0.0403 1
Brugia malayi Protein kinase domain containing protein 0.0254 0.2642 0.2642
Toxoplasma gondii sedoheptulose-1,7-bisphosphatase 0.0346 0.3646 0.3636
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0063
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0019 0.0086 0.0086
Leishmania major protein kinase, putative 0.0014 0.0038 0.0029
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0086 0.0086
Loa Loa (eye worm) phosphofructokinase 0.011 0.1078 0.1078
Onchocerca volvulus 0.0029 0.0199 0.114
Loa Loa (eye worm) hypothetical protein 0.0027 0.018 0.018
Echinococcus multilocularis roundabout 2 0.0013 0.0028 0.0028
Schistosoma mansoni tyrosine kinase 0.0411 0.4358 0.4358
Loa Loa (eye worm) hypothetical protein 0.0165 0.1677 0.1677
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.003 0.0206 0.1406
Brugia malayi G protein-coupled receptor 0.0019 0.0086 0.0086
Brugia malayi metabotropic GABA-B receptor subtype 2 0.0014 0.0031 0.0031
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0109 0.1069 0.8878
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0037 0.0289 0.0281
Echinococcus granulosus peroxidasin 0.0013 0.0028 0.0028
Loa Loa (eye worm) raf kinase 0.0218 0.2253 0.2253
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0015 0.0041 0.0041
Schistosoma mansoni protein phosphatase 2C 0.0016 0.0056 0.0054
Loa Loa (eye worm) hypothetical protein 0.0034 0.0258 0.0258
Schistosoma mansoni hypothetical protein 0.0015 0.0041 0.004
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0015 0.0043 0.0041
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0175 0.1786 0.1786
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0015 0.0007
Echinococcus granulosus JmjC domain containing protein 4 0.0016 0.0056 0.0056
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0016 0.0056 0.0041
Echinococcus granulosus tyrosine protein kinase HCK 0.004 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0021 0.0112 0.0112
Trichomonas vaginalis adenylate and guanylate cyclases, putative 0.0013 0.0022 0.0082
Loa Loa (eye worm) TK protein kinase 0.0051 0.0436 0.0436
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.018 0.018
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0016 0.0056 0.0047
Schistosoma mansoni nck2/grb4 0.0021 0.0112 0.0111
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0021 0.0116 0.1075
Trypanosoma brucei protein kinase, putative 0.0012 0.0015 0.0007
Onchocerca volvulus 0.0019 0.0086 0.0491
Schistosoma mansoni tyrosine kinase 0.0021 0.0116 0.0114
Trypanosoma cruzi STE group serine/threonine-protein kinase, putative 0.0014 0.0038 0.0029
Loa Loa (eye worm) 6-phosphofructokinase 0.011 0.1078 0.1078
Echinococcus multilocularis microtubule associated protein 2 0.0697 0.7467 0.7467
Brugia malayi Variant SH3 domain containing protein 0.0018 0.0082 0.0082
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0317 0.0317
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0021 0.0117 0.0117
Echinococcus granulosus G protein coupled receptor 139 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0058 0.0514 0.0513
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0017 0.0063 0.0596
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.0553 0.0552
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Echinococcus granulosus nuclear factor of activated T cells 5 0.0074 0.0693 0.0693
Onchocerca volvulus 0.0019 0.0086 0.049
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni biogenic amine receptor 0.0019 0.0086 0.0084
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0056 0.0047
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi larval opioid receptor 0.0019 0.0086 0.0086
Schistosoma mansoni lamin 0.0027 0.018 0.0178
Schistosoma mansoni hypothetical protein 0.0014 0.0031 0.003
Echinococcus multilocularis G protein coupled receptor 139 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni phosphatidylserine receptor 0.0016 0.0056 0.0054
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0113 0.0112
Loa Loa (eye worm) sex muscle abnormal protein 5 0.0021 0.0112 0.0112
Brugia malayi Receptor family ligand binding region containing protein 0.0019 0.0086 0.0086
Loa Loa (eye worm) neuropeptide F receptor 0.0019 0.0086 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0086 0.0084
Schistosoma mansoni biogenic amine receptor 0.0019 0.0086 0.0084
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0019 0.0086 0.0086
Brugia malayi sulfakinin receptor protein 0.0019 0.0086 0.0086
Plasmodium falciparum glutathione reductase 0.0017 0.0063 0.1244
Brugia malayi Receptor family ligand binding region containing protein 0.0021 0.0117 0.0117
Echinococcus multilocularis tyrosine protein kinase shark 0.0021 0.0117 0.0117
Schistosoma mansoni lipoxygenase 0.0175 0.1786 0.1785
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0013 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Plasmodium falciparum LCCL domain-containing protein 0.004 0.0317 0.7775
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0017 0.0063 0.0059
Trypanosoma brucei protein kinase, putative 0.0052 0.0453 0.0445
Echinococcus granulosus neuropeptide FF receptor 2 0.0019 0.0086 0.0086
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0019 0.0086 0.0491
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0018 0.0074 0.0074
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0109 0.1069 0.8837
Loa Loa (eye worm) hypothetical protein 0.0021 0.0117 0.0117
Brugia malayi G protein-coupled receptor F59B2.13 0.0019 0.0086 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Loa Loa (eye worm) hypothetical protein 0.0021 0.0112 0.0112
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus granulosus bloom syndrome protein 0.0022 0.0118 0.0118
Onchocerca volvulus 0.0013 0.0022 0.0128
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0063 0.0055
Echinococcus multilocularis thioredoxin glutathione reductase 0.0048 0.0403 0.0403
Echinococcus multilocularis lamin 0.0027 0.018 0.018
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis phd:f box containing protein 0.0016 0.0056 0.0056
Plasmodium falciparum glutathione reductase 0.0048 0.0403 1
Echinococcus granulosus geminin 0.0171 0.1745 0.1745
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.1846 0.6782
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni serine/threonine protein kinase 0.0229 0.2369 0.2368
Onchocerca volvulus 0.0021 0.0116 0.0664
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0017 0.0063 0.1244
Echinococcus multilocularis jumonji domain containing 1A 0.0016 0.0056 0.0056
Plasmodium falciparum JmjC domain-containing protein, putative 0.0016 0.0056 0.1045
Brugia malayi P38 map kinase family protein 2 0.0128 0.1277 0.1277
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Echinococcus multilocularis insulin receptor 0.0254 0.2642 0.2642
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0453 0.0453
Schistosoma mansoni jumonji domain containing protein 0.0016 0.0056 0.0054
Leishmania major ATP-dependent phosphofructokinase 0.011 0.1078 0.107
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Trichomonas vaginalis mercuric reductase, putative 0.0017 0.0063 0.0233
Schistosoma mansoni metabotropic glutamate receptor 0.007 0.0646 0.0644
Echinococcus multilocularis tyrosine protein kinase Btk29A 0.0032 0.0229 0.0229
Echinococcus granulosus mitogen activated protein kinase 11 0.0128 0.1277 0.1277
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.011 0.1078 0.8956
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0017 0.0063 0.0048
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0037 0.0289 0.1063
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0453 0.1666
Brugia malayi Protein kinase domain containing protein 0.0016 0.0057 0.0057
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0453 0.0445
Schistosoma mansoni inositol monophosphatase 0.0037 0.0289 0.0288
Echinococcus multilocularis g protein coupled receptor 0.0019 0.0086 0.0086
Trichomonas vaginalis adenylate cyclase, putative 0.0013 0.0022 0.0082
Echinococcus multilocularis neuropeptide receptor 0.0019 0.0086 0.0086
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0346 0.3646 0.364
Trypanosoma brucei trypanothione reductase 0.0048 0.0403 0.0395
Schistosoma mansoni protein kinase 0.0012 0.0015 0.0014
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0058 0.0514 0.0514
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0095 0.0918 0.0917
Plasmodium falciparum thioredoxin reductase 0.0017 0.0063 0.1244
Giardia lamblia Kinase, CMGC MAPK 0.0052 0.0453 1
Loa Loa (eye worm) TK/INSR protein kinase 0.0254 0.2642 0.2642
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0019 0.0086 0.0084
Schistosoma mansoni jumonji domain containing protein 0.0059 0.053 0.0528
Brugia malayi Metabotropic glutamate receptor precursor. 0.0084 0.0793 0.0793
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0206 0.4546
Trichomonas vaginalis soluble guanylate cyclase gcy, putative 0.0013 0.0022 0.0082
Trypanosoma brucei sedoheptulose-1,7-bisphosphatase 0.0346 0.3646 0.364
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0019 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Leishmania major protein kinase, putative 0.0014 0.0038 0.0029
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0453 0.1666
Echinococcus multilocularis fmrfamide receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0057 0.0057
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0016 0.0056 0.0041
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus multilocularis NCK adaptor protein 0.0021 0.0112 0.0112
Echinococcus granulosus 7TM GPCR rhodopsin 0.0019 0.0086 0.0086
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Schistosoma mansoni roundabout 0.0013 0.0028 0.0027
Brugia malayi Doublecortin family protein 0.004 0.0317 0.0317
Leishmania major cytochrome p450-like protein 0.0016 0.0057 0.0049
Echinococcus multilocularis lipoxygenase domain containing protein 0.004 0.0317 0.0317
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0057 0.0057
Echinococcus multilocularis neuroglian 0.0028 0.0183 0.0183
Brugia malayi Immunoglobulin I-set domain containing protein 0.0017 0.007 0.007
Schistosoma mansoni tyrosine kinase 0.0019 0.0086 0.0084
Schistosoma mansoni hypothetical protein 0.004 0.0317 0.0315
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0019 0.0086 0.0086
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0016 0.0056 0.0047
Echinococcus granulosus lamin dm0 0.0027 0.018 0.018
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0206 0.4922
Brugia malayi protein-tyrosine kinase 0.0051 0.0436 0.0436
Schistosoma mansoni tyrosine kinase 0.0021 0.0117 0.0116
Brugia malayi Immunoglobulin I-set domain containing protein 0.0039 0.0305 0.0305
Echinococcus granulosus alpha 1A adrenergic receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis neuropeptide receptor A26 0.0019 0.0086 0.0086
Echinococcus granulosus dual specificity testis-specific protein kinase 0.0012 0.0015 0.0015
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0019 0.0086 0.0086
Brugia malayi Melatonin receptor type 1A 0.0019 0.0086 0.0086
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Toxoplasma gondii 6-phosphofructokinase 0.003 0.0206 0.0191
Entamoeba histolytica SH2-protein kinase domain containing protein 0.0012 0.0014 0.0134
Loa Loa (eye worm) hypothetical protein 0.0103 0.1004 0.1004
Echinococcus granulosus Immunoglobulin 0.0021 0.0113 0.0113
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Echinococcus multilocularis netrin receptor unc 5 0.0021 0.0116 0.0116
Brugia malayi Peroxidasin 0.0013 0.0028 0.0028
Loa Loa (eye worm) hypothetical protein 0.0013 0.0026 0.0026
Toxoplasma gondii fructose-bisphospatase I 0.0346 0.3646 0.3636
Echinococcus multilocularis neurotracting:lsamp:neurotrimin:obcam 0.0013 0.0028 0.0028
Schistosoma mansoni rab6-interacting 0.004 0.0317 0.0315
Entamoeba histolytica recQ family helicase, putative 0.0012 0.0009 0.008
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis tyrosine protein kinase Fps85D 0.0021 0.0116 0.0116
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0019 0.0086 0.0084
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0019 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0061 0.0549 0.0548
Echinococcus multilocularis tyrosine protein kinase otk 0.0013 0.0028 0.0028
Plasmodium vivax 6-phosphofructokinase, putative 0.003 0.0206 0.4546
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0057 0.0049
Onchocerca volvulus 0.0019 0.0086 0.0491
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase Lyn 0.0063 0.0564 0.0564
Onchocerca volvulus Basement membrane proteoglycan homolog 0.0013 0.0028 0.016
Echinococcus granulosus tyrosine kinase 0.0051 0.0436 0.0436
Echinococcus multilocularis epidermal growth factor receptor 0.078 0.837 0.837
Echinococcus granulosus g protein coupled receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis neuropeptide FF receptor 2 0.0019 0.0086 0.0086
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0514 0.4472
Echinococcus multilocularis neuropeptides capa receptor 0.0019 0.0086 0.0086
Schistosoma mansoni neuropeptide F-like receptor 0.0019 0.0086 0.0084
Brugia malayi SH2 domain containing protein 0.0021 0.0116 0.0116
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0059 0.053 0.053
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0548 0.0546
Echinococcus multilocularis hemicentin 1 0.0013 0.0028 0.0028
Schistosoma mansoni neuropeptide receptor 0.0019 0.0086 0.0084
Loa Loa (eye worm) hypothetical protein 0.0021 0.0113 0.0113
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0019 0.0086 0.0086
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0453 0.0445
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Echinococcus multilocularis Immunoglobulin 0.0021 0.0113 0.0113
Echinococcus granulosus tachykinin peptides receptor 99D 0.0019 0.0086 0.0086
Brugia malayi Inositol-1 0.0037 0.0289 0.0289
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0254 0.2642 0.2642
Brugia malayi MH2 domain containing protein 0.0121 0.1195 0.1195
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0017 0.0063 0.0596
Echinococcus multilocularis sex peptide receptor 0.0019 0.0086 0.0086
Trichomonas vaginalis DNA helicase recq1, putative 0.0022 0.0118 0.0433
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0206 1
Echinococcus multilocularis metabotropic glutamate receptor 2 0.007 0.0646 0.0646
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0019 0.0086 0.0086
Schistosoma mansoni amine GPCR 0.0019 0.0086 0.0084
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.003 0.0206 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0019 0.0086 0.0086
Schistosoma mansoni tyrosine kinase 0.0254 0.2642 0.2641
Schistosoma mansoni tyrosine kinase 0.0032 0.0229 0.0227
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Schistosoma mansoni hypothetical protein 0.0019 0.0086 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus multilocularis activin receptor type 0.0012 0.0015 0.0015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Brugia malayi putative neuropeptide receptor 0.0019 0.0086 0.0086
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Echinococcus multilocularis 0.024 0.2489 0.2489
Echinococcus granulosus Aryl hydrocarbon receptor nuclear 0.0013 0.0022 0.0022
Echinococcus granulosus roundabout 2 0.0013 0.0028 0.0028
Echinococcus multilocularis tyrosine protein kinase Fgr 0.0061 0.0549 0.0549
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus multilocularis roundabout 2 0.0013 0.0028 0.0028
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus granulosus dro:myosuppressin receptor 0.0019 0.0086 0.0086
Brugia malayi follicle stimulating hormone receptor 0.0019 0.0086 0.0086
Schistosoma mansoni nephrin 0.0028 0.0183 0.0182
Leishmania major trypanothione reductase 0.0048 0.0403 0.0395
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus multilocularis aryl hydrocarbon receptor 0.0013 0.0022 0.0022
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0021 0.0113 0.0112
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0121 0.1201 1
Onchocerca volvulus 0.0019 0.0086 0.0491
Echinococcus granulosus lysine specific demethylase 5A 0.0061 0.0548 0.0548
Brugia malayi Dopamine receptor 0.0019 0.0086 0.0086
Echinococcus granulosus cpg binding protein 0.0031 0.0217 0.0217
Schistosoma mansoni hypothetical protein 0.0019 0.0086 0.0084
Schistosoma mansoni vav2 0.0018 0.0082 0.0081
Loa Loa (eye worm) hypothetical protein 0.0016 0.0056 0.0056
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0022 0.0082
Brugia malayi CXXC zinc finger family protein 0.0029 0.0199 0.0199
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.003 0.0206 0.4545
Schistosoma mansoni loxhd1 0.004 0.0317 0.0315
Trypanosoma brucei mitogen-activated protein kinase 3, putative 0.0128 0.1277 0.127
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0051 0.0436 0.0436
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0086 0.0086
Echinococcus granulosus single minded 2 0.0036 0.0279 0.0279
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0059
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Schistosoma mansoni jumonji/arid domain-containing protein 0.0061 0.0548 0.0546
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine protein kinase Src64B 0.0061 0.0549 0.0549
Echinococcus granulosus tyrosine kinase 0.0021 0.0116 0.0116
Onchocerca volvulus 0.0019 0.0086 0.0491
Schistosoma mansoni opsin-like receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Schistosoma mansoni biogenic amine (5HT) receptor 0.0019 0.0086 0.0084
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0022 0.0082
Brugia malayi G-protein coupled receptor 0.0019 0.0086 0.0086
Loa Loa (eye worm) hypothetical protein 0.004 0.0317 0.0317
Loa Loa (eye worm) TK protein kinase 0.004 0.032 0.032
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus g protein coupled receptor 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0019 0.0086 0.0491
Brugia malayi Cytochrome P450 family protein 0.0016 0.0057 0.0057
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0017 0.0063 0.0055
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0019 0.0086 0.0084
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.2721 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0019 0.0086 0.0084
Brugia malayi hypothetical protein 0.0019 0.0086 0.0086
Leishmania major mitogen-activated protein kinase 3, putative,map kinase 3, putative 0.0128 0.1277 0.127
Echinococcus granulosus epidermal growth factor receptor 0.078 0.837 0.837
Schistosoma mansoni neuropeptide f receptor 76f 0.0019 0.0086 0.0084
Loa Loa (eye worm) SRC-1 0.0061 0.0549 0.0549
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0017 0.0063 0.0055
Brugia malayi Sex muscle abnormal protein 5 0.0021 0.0112 0.0112
Toxoplasma gondii phosphofructokinase domain-containing protein 0.003 0.0206 0.0191
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0017 0.0063 0.0059
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.093 1 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0019 0.0086 0.0086
Trypanosoma cruzi sedoheptulose-1,7-bisphosphatase, putative 0.0346 0.3646 0.364
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0059 0.053 0.053
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0016 0.0056 0.0054
Trypanosoma cruzi trypanothione reductase, putative 0.0048 0.0403 0.0395
Echinococcus granulosus tyrosine protein kinase otk 0.0013 0.0028 0.0028
Echinococcus granulosus neuropeptide s receptor 0.0019 0.0086 0.0086
Echinococcus granulosus tm gpcr rhodopsin 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0027 0.018 0.103
Loa Loa (eye worm) hypothetical protein 0.0015 0.0041 0.0041
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0261 0.2721 0.2721
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.1078 0.107
Mycobacterium ulcerans 6-phosphofructokinase 0.011 0.1078 1
Schistosoma mansoni protein kinase 0.0012 0.0015 0.0014
Onchocerca volvulus 0.0019 0.0086 0.0491
Trypanosoma cruzi PAS-domain containing phosphoglycerate kinase, putative 0.0013 0.0022 0.0014
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0021 0.0116 0.0664
Echinococcus multilocularis rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Brugia malayi RhoGAP domain containing protein 0.0018 0.0082 0.0082
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0019 0.0086 0.0086
Onchocerca volvulus 0.0019 0.0086 0.0491
Loa Loa (eye worm) CAMK/MLCK protein kinase 0.0015 0.0043 0.0043
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0028 0.0188 0.0188
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus Polycystic kidney disease protein 0.004 0.0317 0.0317
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Brugia malayi Immunoglobulin I-set domain containing protein 0.0013 0.0028 0.0028
Loa Loa (eye worm) G-protein coupled receptor 0.0019 0.0086 0.0086
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0014 0.004 0.0025
Trypanosoma cruzi STE/STE11 serine/threonine-protein kinase, putative 0.0014 0.0038 0.0029
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Brugia malayi ORL1-like opioid receptor 0.0019 0.0086 0.0086
Echinococcus granulosus neuropeptide receptor A26 0.0019 0.0086 0.0086
Echinococcus granulosus lachesin 0.0013 0.0028 0.0028
Trypanosoma brucei STE/STE11 serine/threonine-protein kinase, putative 0.0012 0.0015 0.0007
Trypanosoma brucei fructose-1,6-bisphosphatase 0.093 1 1
Plasmodium vivax JmjC domain containing protein 0.0016 0.0056 0.0382
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0057 0.0049
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0058 0.0514 0.0514
Echinococcus multilocularis neuropeptide s receptor 0.0019 0.0086 0.0086
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0019 0.0086 0.0084
Schistosoma mansoni growth factor receptor-bound protein 0.0021 0.0112 0.0111
Schistosoma mansoni tyrosine kinase 0.0032 0.0229 0.0227
Loa Loa (eye worm) hypothetical protein 0.0013 0.0028 0.0028
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.011 0.1078 0.107
Echinococcus multilocularis cpg binding protein 0.0031 0.0217 0.0217
Brugia malayi RE15519p 0.0019 0.0086 0.0086
Echinococcus granulosus tyrosine kinase|tyrosine protein kinase Fyn 0.0051 0.0436 0.0436
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Onchocerca volvulus Poor gastrulation protein homolog 0.0014 0.0031 0.0178
Brugia malayi Tyrosine-protein kinase abl-1 0.0111 0.1095 0.1095
Echinococcus multilocularis tyrosine protein kinase ABL1 0.023 0.2382 0.2382
Echinococcus granulosus lipoxygenase domain containing protein 0.004 0.0317 0.0317
Brugia malayi GnHR receptor homolog 0.0019 0.0086 0.0086
Schistosoma mansoni neuropeptide receptor 0.0019 0.0086 0.0084
Echinococcus multilocularis inositol monophosphatase 1 0.0037 0.0289 0.0289
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Echinococcus multilocularis tyrosine protein kinase lyn tyrosine protein kinase blk 0.0061 0.0549 0.0549
Entamoeba histolytica phosphofructokinase, putative 0.011 0.1078 1
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Schistosoma mansoni proto-oncogene tyrosine-protein kinase abl1 0.0021 0.0112 0.0111
Echinococcus multilocularis contactin neuroglian septate junction protein 0.0013 0.0028 0.0028
Echinococcus granulosus neuropeptide Y receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis neuropeptide Y receptor 0.0019 0.0086 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus multilocularis tyrosine protein kinase Abl 0.0111 0.1095 0.1095
Loa Loa (eye worm) TK/FER protein kinase 0.0021 0.0116 0.0116
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0026 0.0026
Trichomonas vaginalis DNA helicase recq, putative 0.0022 0.0118 0.0433
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0453 0.0439
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0819 0.8794 0.8794
Echinococcus granulosus 3'partial|tyrosine protein kinase Fgr 0.0061 0.0549 0.0549
Echinococcus granulosus guanine nucleotide exchange factor VAV2 0.0018 0.0082 0.0082
Echinococcus multilocularis lachesin 0.0013 0.0028 0.0028
Echinococcus granulosus biogenic amine 5HT receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis Ankyrin 0.0015 0.0043 0.0043
Brugia malayi Death domain containing protein 0.0015 0.0041 0.0041
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.003 0.0206 0.4922
Schistosoma mansoni inositol monophosphatase 0.0037 0.0289 0.0288
Echinococcus granulosus rhodopsin orphan GPCR 0.0019 0.0086 0.0086
Loa Loa (eye worm) thioredoxin reductase 0.0048 0.0403 0.0403
Loa Loa (eye worm) RhoGAP domain-containing protein 0.0018 0.0082 0.0082
Schistosoma mansoni tyrosine kinase 0.0411 0.4358 0.4358
Onchocerca volvulus 0.0021 0.0116 0.0664
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0042 0.0042
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0548 0.0548
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Echinococcus granulosus tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0019 0.0086 0.0084
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0261 0.2721 0.2721
Brugia malayi SRC-1 0.0061 0.0549 0.0549
Trichomonas vaginalis 6-phosphofructokinase, putative 0.003 0.0206 0.0757
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Echinococcus granulosus hemicentin 1 0.0013 0.0028 0.0028
Loa Loa (eye worm) TK/EGFR protein kinase 0.078 0.837 0.837
Echinococcus multilocularis tyrosine protein kinase Src64B 0.0061 0.0549 0.0549
Loa Loa (eye worm) RGC/RGC protein kinase 0.0019 0.0086 0.0086
Trichomonas vaginalis phosphofructokinase, putative 0.003 0.0206 0.0757
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0017 0.0063 0.0063
Onchocerca volvulus 0.0019 0.0086 0.0491
Brugia malayi neuropeptide F receptor 0.0019 0.0086 0.0086
Brugia malayi Variant SH3 domain containing protein 0.0021 0.0112 0.0112
Schistosoma mansoni tyrosine kinase 0.0061 0.0549 0.0548
Schistosoma mansoni myosin xvIII 0.0019 0.0086 0.0084
Brugia malayi Prion-like- 0.0013 0.0028 0.0028
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0019 0.0086 0.0086
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.1745 0.6414
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0037 0.0289 0.0274
Echinococcus granulosus lysine specific demethylase 6a 0.0016 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0086 0.0086
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0058 0.0514 0.4472
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0017 0.0063 0.0055
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0013 0.0028 0.0028
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.011 0.1078 1
Brugia malayi Cytochrome P450 family protein 0.0016 0.0057 0.0057
Echinococcus multilocularis JmjC domain containing protein 4 0.0016 0.0056 0.0056
Onchocerca volvulus Netrin receptor homolog 0.0021 0.0111 0.0636
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0019 0.0086 0.0086
Echinococcus multilocularis tyrosine protein kinase Fyn 0.0061 0.0549 0.0549
Trypanosoma cruzi mitogen-activated protein kinase 3, putative 0.0128 0.1277 0.127
Brugia malayi Furin-like cysteine rich region family protein 0.078 0.837 0.837
Echinococcus granulosus fructose 16 bisphosphatase 1 0.093 1 1
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Trypanosoma cruzi fructose-1,6-bisphosphatase, cytosolic, putative 0.093 1 1
Brugia malayi hypothetical protein 0.0165 0.1677 0.1677
Mycobacterium tuberculosis Probable oxidoreductase 0.0121 0.1201 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0017 0.0063 0.0055
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0054 0.0471 0.0471
Echinococcus granulosus netrin receptor unc 5 0.0021 0.0116 0.0116
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0058 0.0514 0.3959
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0019 0.0086 0.0086
Echinococcus multilocularis mitogen activated protein kinase 14 0.0128 0.1277 0.1277
Echinococcus granulosus metabotropic glutamate receptor 5 0.0103 0.1004 0.1004
Mycobacterium tuberculosis Probable dehydrogenase 0.0109 0.1069 0.8837
Loa Loa (eye worm) hypothetical protein 0.0015 0.0043 0.0043
Brugia malayi Protein kinase domain containing protein 0.0021 0.0116 0.0116
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0012 0.0016 0.0016
Echinococcus granulosus jumonji domain containing 1A 0.0016 0.0056 0.0056
Echinococcus multilocularis serotonin receptor 0.0019 0.0086 0.0086
Schistosoma mansoni aryl hydrocarbon receptor 0.0049 0.0418 0.0417
Echinococcus multilocularis raf serine:threonine protein kinase 0.0229 0.2369 0.2369
Echinococcus granulosus tyrosine protein kinase Src42A 0.0061 0.0549 0.0549
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0013 0.0028 0.0027
Schistosoma mansoni tyrosine kinase 0.0422 0.4475 0.4474
Echinococcus multilocularis receptor type guanylyl cyclase 0.0019 0.0086 0.0086
Loa Loa (eye worm) doublecortin family protein 0.004 0.0317 0.0317
Brugia malayi phosphofructokinase 0.011 0.1078 0.1078
Schistosoma mansoni lipoxygenase 0.0103 0.1006 0.1005
Echinococcus multilocularis proto oncogene tyrosine protein kinase LCK 0.0061 0.0549 0.0549

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

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