Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | rodhanase-like domain containing protein | 0.012 | 0.3242 | 0.9608 |
Echinococcus multilocularis | ETHE1 protein | 0.0034 | 0.0482 | 0.0482 |
Trypanosoma brucei | cleavage and polyadenylation specificity factor subunit, putative | 0.0034 | 0.0482 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.094 | 0.1017 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.007 | 0.007 |
Echinococcus granulosus | tar DNA binding protein | 0.0208 | 0.6097 | 0.6097 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0158 | 0.4474 | 0.4474 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.004 | 0.0679 | 0.0679 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0482 | 0.0984 |
Brugia malayi | Rhodanese-like domain containing protein | 0.012 | 0.3242 | 0.346 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0241 | 0.7164 | 0.7756 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0044 | 0.0804 | 0.1992 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0482 | 0.0984 |
Schistosoma mansoni | hydroxyacylglutathione hydrolase (Glyoxalase II) (Glx II) | 0.0034 | 0.0482 | 0.0674 |
Trypanosoma brucei | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0482 | 0.0984 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0449 |
Loa Loa (eye worm) | acetyltransferase | 0.0143 | 0.4003 | 0.4334 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0023 | 0.0129 | 0.0139 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.1174 | 0.1271 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0124 | 0.3368 | 0.471 |
Echinococcus granulosus | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0061 | 0.134 | 0.134 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0034 | 0.0482 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.4474 | 0.4843 |
Trichomonas vaginalis | A-type flavoprotein | 0.0034 | 0.0482 | 0.0347 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.1893 | 0.1904 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0381 | 0.0237 |
Echinococcus multilocularis | tumor protein p63 | 0.0329 | 1 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0023 | 0.0133 | 0.0144 |
Onchocerca volvulus | Putative hydrolase PNKD | 0.0034 | 0.0482 | 0.0712 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0057 | 0.1209 | 0.1308 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0482 | 0.1282 |
Schistosoma mansoni | bromodomain containing protein | 0.0074 | 0.1775 | 0.2482 |
Wolbachia endosymbiont of Brugia malayi | metallo-beta-lactamase superfamily hydrolase | 0.0034 | 0.0482 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0241 | 0.7151 | 0.7151 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.007 | 0.0098 |
Schistosoma mansoni | polycystin 1-related | 0.0021 | 0.007 | 0.0098 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0124 | 0.3368 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0792 | 0.0689 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0488 | 0.0528 |
Echinococcus multilocularis | muscleblind protein | 0.0158 | 0.4474 | 0.4474 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.7151 | 1 |
Brugia malayi | Bromodomain containing protein | 0.0087 | 0.2196 | 0.2319 |
Entamoeba histolytica | metallo-beta-lactamase family protein | 0.0034 | 0.0482 | 0.0984 |
Trichomonas vaginalis | chromobox protein, putative | 0.0078 | 0.1893 | 0.1904 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0482 | 0.0521 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0034 | 0.0482 | 0.0347 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0143 | 0.4003 | 0.429 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0124 | 0.3368 | 0.3529 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0044 | 0.0804 | 0.0703 |
Brugia malayi | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0061 | 0.134 | 0.1385 |
Echinococcus granulosus | serine protein kinase ATM | 0.0024 | 0.0167 | 0.0167 |
Echinococcus multilocularis | eukaryotic initiation factor 4A III | 0.0124 | 0.3368 | 0.3368 |
Entamoeba histolytica | DEAD/DEAH box helicase, putative | 0.0124 | 0.3368 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0482 | 0.0674 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0241 | 0.7151 | 0.7151 |
Trypanosoma cruzi | Eukaryotic initiation factor 4A-1 | 0.0124 | 0.3368 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.007 | 0.1646 | 0.1646 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.007 | 0.0098 |
Brugia malayi | ethe1-prov protein | 0.0034 | 0.0482 | 0.0449 |
Echinococcus multilocularis | serine protein kinase ATM | 0.0024 | 0.0167 | 0.0167 |
Chlamydia trachomatis | ribonuclease Z | 0.0034 | 0.0482 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0208 | 0.6097 | 0.66 |
Mycobacterium tuberculosis | Probable cold-shock DeaD-box protein A homolog DeaD (ATP-dependent RNA helicase dead homolog) | 0.0124 | 0.3368 | 0.7893 |
Trichomonas vaginalis | cdc25b, putative | 0.012 | 0.3242 | 0.3391 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4804 | 0.6718 |
Trypanosoma brucei | Eukaryotic initiation factor 4A-1 | 0.0124 | 0.3368 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0241 | 0.7151 | 0.7151 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0034 | 0.0482 | 0.0984 |
Giardia lamblia | Translation initiation factor eIF-4A, putative | 0.0124 | 0.3368 | 1 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0038 | 0.0608 | 0.0438 |
Echinococcus granulosus | Polycystic kidney disease protein | 0.0021 | 0.007 | 0.007 |
Plasmodium vivax | unspecified product | 0.0034 | 0.0482 | 0.1248 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0129 | 0.018 |
Brugia malayi | Muscleblind-like protein | 0.0158 | 0.4474 | 0.4804 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0609 | 0.0851 |
Onchocerca volvulus | 0.012 | 0.3242 | 0.5489 | |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0127 | 0.3476 | 0.3476 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0208 | 0.6097 | 0.66 |
Brugia malayi | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0449 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Toxoplasma gondii | eukaryotic initiation factor-4A, putative | 0.0124 | 0.3368 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0034 | 0.0482 | 0.0347 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.007 | 0.0076 |
Trypanosoma cruzi | phosphatidylinositol kinase related protein, putative | 0.0024 | 0.0167 | 0.033 |
Echinococcus granulosus | ETHE1 protein | 0.0034 | 0.0482 | 0.0482 |
Onchocerca volvulus | 0.0034 | 0.0482 | 0.0712 | |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.0792 | 0.1249 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0394 | 0.0353 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0034 | 0.0482 | 0.0482 |
Brugia malayi | hypothetical protein | 0.0034 | 0.0482 | 0.0449 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0061 | 0.134 | 0.2348 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.1893 | 0.1893 |
Toxoplasma gondii | hydroxyacylglutathione hydrolase | 0.0034 | 0.0482 | 0.0984 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0061 | 0.134 | 0.2348 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3242 | 0.351 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Schistosoma mansoni | rab6-interacting | 0.0021 | 0.007 | 0.0098 |
Echinococcus multilocularis | zinc finger protein | 0.0025 | 0.0202 | 0.0202 |
Echinococcus granulosus | m phase inducer phosphatasecdc25 | 0.012 | 0.3242 | 0.3242 |
Echinococcus multilocularis | RUN | 0.0021 | 0.007 | 0.007 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0482 | 0.0521 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.012 | 0.3242 | 0.3391 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase | 0.0034 | 0.0482 | 0.0521 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0137 | 0.3791 | 0.3791 |
Entamoeba histolytica | type A flavoprotein, putative | 0.0034 | 0.0482 | 0.0984 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.007 | 0.1646 | 0.1646 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.0057 | 0.0062 |
Treponema pallidum | ATP-dependent RNA helicase | 0.0124 | 0.3368 | 1 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0047 | 0.0898 | 0.1433 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0127 | 0.3476 | 0.3476 |
Echinococcus granulosus | zinc finger protein | 0.0025 | 0.0202 | 0.0202 |
Echinococcus multilocularis | eukaryotic initiation factor 4A | 0.0124 | 0.3368 | 0.3368 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.7151 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.4804 | 0.6718 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0025 | 0.0198 | 0.0276 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.2941 | 0.3184 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.1174 | 0.1205 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Schistosoma mansoni | ataxia telangiectasia mutated (atm) | 0.0024 | 0.0167 | 0.0233 |
Onchocerca volvulus | 0.0034 | 0.0482 | 0.0712 | |
Echinococcus granulosus | eukaryotic initiation factor 4A III | 0.0124 | 0.3368 | 0.3368 |
Schistosoma mansoni | tar DNA-binding protein | 0.0208 | 0.6097 | 0.8526 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0038 | 0.0608 | 0.1631 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0124 | 0.3368 | 0.3529 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0241 | 0.7151 | 0.7741 |
Brugia malayi | eukaryotic initiation factor 4A | 0.0124 | 0.3368 | 0.3597 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0482 | 0.0674 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0048 | 0.094 | 0.1314 |
Onchocerca volvulus | Hydroxyacylglutathione hydrolase, mitochondrial homolog | 0.0034 | 0.0482 | 0.0712 |
Echinococcus granulosus | lipoxygenase domain containing protein | 0.0021 | 0.007 | 0.007 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Brugia malayi | chromobox protein homolog 3 | 0.0044 | 0.0792 | 0.0787 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.012 | 0.3242 | 0.9608 |
Schistosoma mansoni | loxhd1 | 0.0021 | 0.007 | 0.0098 |
Echinococcus granulosus | metallo beta lactamase domain containing protein | 0.0034 | 0.0482 | 0.0482 |
Mycobacterium tuberculosis | Class a beta-lactamase BlaC | 0.0147 | 0.4138 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0262 | 0.7834 | 0.8481 |
Trypanosoma cruzi | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0482 | 0.1282 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0211 | 0.6198 | 0.6649 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.1032 | 0.1117 |
Echinococcus multilocularis | zinc phosphodiesterase | 0.0034 | 0.0482 | 0.0482 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0034 | 0.0482 | 0.0482 |
Echinococcus multilocularis | metallo beta lactamase domain containing protein | 0.0034 | 0.0482 | 0.0482 |
Schistosoma mansoni | 3-hydroxyacyl-CoA dehydrogenase | 0.0061 | 0.134 | 0.1874 |
Entamoeba histolytica | alkyl sulfatase, putative | 0.0034 | 0.0482 | 0.0984 |
Echinococcus multilocularis | hydroxyacylglutathione hydrolase | 0.0034 | 0.0482 | 0.0482 |
Echinococcus multilocularis | 3 hydroxyacyl coenzyme A dehydrogenase type 2 | 0.0061 | 0.134 | 0.134 |
Brugia malayi | Chain A, Human Glyoxalase Ii With Cacodylate And Acetate Ions Present In The Active Site. | 0.0034 | 0.0482 | 0.0449 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.012 | 0.3242 | 0.3391 |
Echinococcus multilocularis | m phase inducer phosphatase(cdc25) | 0.012 | 0.3242 | 0.3242 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.012 | 0.3242 | 0.3391 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.0306 | 0.9237 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0609 | 0.0659 |
Brugia malayi | Phosphatidylinositol 3- and 4-kinase family protein | 0.0024 | 0.0167 | 0.0105 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0241 | 0.7151 | 1 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.1893 | 0.1893 |
Entamoeba histolytica | rodhanase-like domain containing protein | 0.012 | 0.3242 | 0.9608 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0482 | 0.1282 |
Brugia malayi | Heterochromatin protein 1 | 0.0078 | 0.1893 | 0.1989 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Trichomonas vaginalis | cdc25c, putative | 0.012 | 0.3242 | 0.3391 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0038 | 0.0609 | 0.0588 |
Mycobacterium ulcerans | class a beta-lactamase, BlaC | 0.0147 | 0.4138 | 1 |
Onchocerca volvulus | 0.012 | 0.3242 | 0.5489 | |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0025 | 0.0198 | 0.0198 |
Brugia malayi | follicle stimulating hormone receptor | 0.0241 | 0.7164 | 0.7738 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.0306 | 0.9237 | 1 |
Plasmodium vivax | RNA helicase-1, putative | 0.0124 | 0.3368 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0143 | 0.4003 | 0.4003 |
Mycobacterium leprae | PROBABLE CONSERVED LIPOPROTEIN LPQF | 0.0071 | 0.1667 | 1 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0124 | 0.3368 | 1 |
Onchocerca volvulus | Glucosylceramidase homolog | 0.0201 | 0.585 | 1 |
Brugia malayi | Cytochrome P450 family protein | 0.0023 | 0.0118 | 0.0052 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0038 | 0.0608 | 0.1379 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.004 | 0.0679 | 0.0679 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.2941 | 0.3184 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0034 | 0.0482 | 0.1282 |
Brugia malayi | RNA binding protein | 0.0208 | 0.6097 | 0.6574 |
Brugia malayi | Bromodomain containing protein | 0.0046 | 0.0876 | 0.0879 |
Trichomonas vaginalis | mitotic inducer phosphatase CDC25, putative | 0.012 | 0.3242 | 0.3391 |
Loa Loa (eye worm) | hypothetical protein | 0.0021 | 0.007 | 0.0076 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0482 | 0.1282 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0482 | 0.0521 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.0898 | 0.0807 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0034 | 0.0482 | 0.0674 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0025 | 0.0198 | 0.0198 |
Loa Loa (eye worm) | hydroxyacylglutathione hydrolase cytoplasmic | 0.0034 | 0.0482 | 0.0521 |
Schistosoma mansoni | m-phase inducer phosphatase(cdc25) | 0.012 | 0.3242 | 0.4534 |
Schistosoma mansoni | lipoxygenase | 0.0089 | 0.2245 | 0.314 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0044 | 0.0792 | 0.0689 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0143 | 0.4003 | 0.5598 |
Loa Loa (eye worm) | doublecortin family protein | 0.0021 | 0.007 | 0.0076 |
Onchocerca volvulus | 0.0048 | 0.094 | 0.1505 | |
Entamoeba histolytica | hypothetical protein, conserved | 0.0034 | 0.0482 | 0.0984 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0262 | 0.7834 | 0.8481 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0984 |
Trypanosoma cruzi | metallo-beta-lactamase superfamily, putative | 0.0034 | 0.0482 | 0.1282 |
Echinococcus granulosus | zinc phosphodiesterase | 0.0034 | 0.0482 | 0.0482 |
Schistosoma mansoni | DEAD box ATP-dependent RNA helicase | 0.0124 | 0.3368 | 0.471 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0482 | 0.0521 |
Toxoplasma gondii | metallo-beta-lactamase domain-containing protein | 0.0034 | 0.0482 | 0.0984 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0241 | 0.7151 | 0.7151 |
Onchocerca volvulus | 0.012 | 0.3242 | 0.5489 | |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0792 | 0.0857 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.1893 | 0.2648 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0482 | 0.1282 |
Onchocerca volvulus | 0.0034 | 0.0488 | 0.0723 | |
Loa Loa (eye worm) | hypothetical protein | 0.0079 | 0.1931 | 0.2091 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.1174 | 0.1271 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0031 | 0.0381 | 0.0237 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0044 | 0.0804 | 0.2226 |
Trichomonas vaginalis | cdc25b, putative | 0.012 | 0.3242 | 0.3391 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0241 | 0.7151 | 0.7724 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0061 | 0.134 | 0.2348 |
Loa Loa (eye worm) | hypothetical protein | 0.0124 | 0.3368 | 0.3646 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0208 | 0.6097 | 0.6574 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Schistosoma mansoni | zinc phosphodiesterase | 0.0034 | 0.0482 | 0.0674 |
Brugia malayi | TAR-binding protein | 0.0208 | 0.6097 | 0.6574 |
Plasmodium falciparum | eukaryotic initiation factor 4A | 0.0124 | 0.3368 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0043 | 0.0767 | 0.083 |
Echinococcus multilocularis | chromobox protein 1 | 0.0078 | 0.1893 | 0.1893 |
Mycobacterium tuberculosis | Probable conserved lipoprotein LpqF | 0.0071 | 0.1667 | 0.3243 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Echinococcus granulosus | muscleblind protein | 0.0158 | 0.4474 | 0.4474 |
Leishmania major | eukaryotic initiation factor 4a, putative | 0.0124 | 0.3368 | 1 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Trichomonas vaginalis | beta lactamase domain, putative | 0.0034 | 0.0482 | 0.0347 |
Trypanosoma brucei | hydroxyacylglutathione hydrolase, putative | 0.0034 | 0.0482 | 0.0984 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0044 | 0.0804 | 0.0804 |
Plasmodium falciparum | cytosolic glyoxalase II | 0.0034 | 0.0482 | 0.1248 |
Trichomonas vaginalis | m-phase inducer phosphatase, putative | 0.012 | 0.3242 | 0.3391 |
Entamoeba histolytica | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0984 |
Trypanosoma brucei | glyoxalase II | 0.0034 | 0.0482 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.3242 | 0.351 |
Mycobacterium ulcerans | lipoprotein LpqF | 0.0071 | 0.1667 | 0.3243 |
Brugia malayi | Rhodanese-like domain containing protein | 0.012 | 0.3242 | 0.346 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0211 | 0.6198 | 0.6649 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.4474 | 0.4843 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.585 | 0.6265 |
Trichomonas vaginalis | DEAD box ATP-dependent RNA helicase, putative | 0.0124 | 0.3368 | 0.3529 |
Echinococcus granulosus | geminin | 0.0168 | 0.4804 | 0.4804 |
Schistosoma mansoni | chromobox protein | 0.0078 | 0.1893 | 0.2648 |
Echinococcus granulosus | chromobox protein 1 | 0.0078 | 0.1893 | 0.1893 |
Onchocerca volvulus | 0.012 | 0.3242 | 0.5489 | |
Schistosoma mansoni | zinc finger protein | 0.0025 | 0.0202 | 0.0282 |
Echinococcus granulosus | hydroxyacylglutathione hydrolase | 0.0034 | 0.0482 | 0.0482 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0023 | 0.0118 | 0.0127 |
Echinococcus multilocularis | lipoxygenase domain containing protein | 0.0021 | 0.007 | 0.007 |
Echinococcus granulosus | RUN | 0.0021 | 0.007 | 0.007 |
Leishmania major | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0061 | 0.134 | 0.2974 |
Trypanosoma cruzi | metallo-beta-lactamase-like protein, putative | 0.0034 | 0.0482 | 0.1282 |
Echinococcus multilocularis | tar DNA binding protein | 0.0208 | 0.6097 | 0.6097 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0078 | 0.1893 | 0.205 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0306 | 0.9237 | 1 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0044 | 0.0804 | 0.0703 |
Onchocerca volvulus | Eukaryotic initiation factor 4A homolog | 0.0124 | 0.3368 | 0.5706 |
Loa Loa (eye worm) | metallo-beta-lactamase superfamily protein | 0.0034 | 0.0482 | 0.0521 |
Schistosoma mansoni | hypothetical protein | 0.0034 | 0.0482 | 0.0674 |
Trichomonas vaginalis | chromobox protein, putative | 0.0047 | 0.0898 | 0.0807 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.0482 | 0.0347 |
Echinococcus multilocularis | geminin | 0.0168 | 0.4804 | 0.4804 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0044 | 0.0804 | 0.1992 |
Echinococcus multilocularis | Polycystic kidney disease protein | 0.0021 | 0.007 | 0.007 |
Echinococcus granulosus | eukaryotic initiation factor 4A | 0.0124 | 0.3368 | 0.3368 |
Trypanosoma cruzi | glyoxalase II | 0.0034 | 0.0482 | 0.1282 |
Trypanosoma brucei | beta lactamase | 0.0071 | 0.1667 | 0.4688 |
Brugia malayi | MH2 domain containing protein | 0.0262 | 0.7834 | 0.8469 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0963 | 0.1043 |
Plasmodium vivax | hydroxyacyl glutathione hydrolase, putative | 0.0034 | 0.0482 | 0.1248 |
Loa Loa (eye worm) | TAR-binding protein | 0.0208 | 0.6097 | 0.66 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.1174 | 0.1205 |
Schistosoma mansoni | lipoxygenase | 0.0127 | 0.3476 | 0.4861 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.06 ug ml-1 | In vitro minimum inhibitory concentration against Enterococcus faecalis ATCC 29212. | ChEMBL. | 8289194 |
MIC (functional) | = 0.12 ug ml-1 | In vitro minimum inhibitory concentration against S. aureus UBMS 90-3 (sensitive). | ChEMBL. | 8289194 |
MIC (functional) | = 0.25 ug ml-1 | In vitro minimum inhibitory concentration against S. aureus smith (sensitive). | ChEMBL. | 8289194 |
MIC (functional) | = 0.5 ug ml-1 | In vitro minimum inhibitory concentration against E. coli J3272 (tet D efflux). | ChEMBL. | 8289194 |
MIC (functional) | = 0.5 ug ml-1 | In vitro minimum inhibitory concentration against S. aureus UBMS 90-1 (tet M ribosomal protection). | ChEMBL. | 8289194 |
MIC (functional) | = 1 ug ml-1 | In vitro minimum inhibitory concentration against E. coli UBMS 88-1 (tet B efflux). | ChEMBL. | 8289194 |
MIC (functional) | = 1 ug ml-1 | In vitro minimum inhibitory concentration against E. coli UBMS 90-4 (tet M ribosomal protection). | ChEMBL. | 8289194 |
MIC (functional) | = 2 ug ml-1 | In vitro minimum inhibitory concentration against E. coli UBMS 90-5 (sensitive). | ChEMBL. | 8289194 |
MIC (functional) | = 4 ug ml-1 | In vitro minimum inhibitory concentration against E. coli J3272 (tet C efflux). | ChEMBL. | 8289194 |
MIC (functional) | = 4 ug ml-1 | In vitro minimum inhibitory concentration against S. aureus UBMS 88-7 (tet K efflux). | ChEMBL. | 8289194 |
MIC (functional) | = 8 ug ml-1 | In vitro minimum inhibitory concentration against E. coli PRP-1 (tet A efflux). | ChEMBL. | 8289194 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.