Detailed information for compound 803636

Basic information

Technical information
  • TDR Targets ID: 803636
  • Name: 2-[[2-(3-methoxyphenyl)-5-phenyl-1H-imidazol- 4-yl]sulfanyl]-N-(3-methoxypropyl)acetamide
  • MW: 411.517 | Formula: C22H25N3O3S
  • H donors: 2 H acceptors: 2 LogP: 3.58 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: COCCCNC(=O)CSc1[nH]c(nc1c1ccccc1)c1cccc(c1)OC
  • InChi: 1S/C22H25N3O3S/c1-27-13-7-12-23-19(26)15-29-22-20(16-8-4-3-5-9-16)24-21(25-22)17-10-6-11-18(14-17)28-2/h3-6,8-11,14H,7,12-13,15H2,1-2H3,(H,23,26)(H,24,25)
  • InChiKey: CSYVTKIUZZKMTA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-[[2-(3-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]thio]-N-(3-methoxypropyl)acetamide
  • 2-[[2-(3-methoxyphenyl)-5-phenyl-1H-imidazol-4-yl]sulfanyl]-N-(3-methoxypropyl)ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus GPCR family 2 0.0017 0.0124 0.0122
Echinococcus granulosus FTZ F1 alpha 0.001 0.0034 0.0013
Echinococcus multilocularis lysine specific demethylase 5A 0.0063 0.0706 0.07
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.001 0.0034 0.0011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.3589 1
Schistosoma mansoni hypothetical protein 0.0103 0.1214 0.1451
Loa Loa (eye worm) hypothetical protein 0.0037 0.0372 0.035
Echinococcus granulosus cpg binding protein 0.0037 0.038 0.0432
Echinococcus multilocularis ecdysone induced protein 78C 0.001 0.0034 0.0011
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.001 0.0034 0.0013
Echinococcus granulosus Peptidase C19 ubiquitin carboxyl terminal hydrolase 2 0.004 0.0419 0.0479
Brugia malayi steroid hormone receptor 0.001 0.0034 0.0025
Echinococcus granulosus dnaJ subfamily B 0.0447 0.554 0.6654
Entamoeba histolytica serine/threonine protein kinase, putative 0.0103 0.1211 0.9626
Loa Loa (eye worm) DNA-binding protein D-ETS-3 0.0011 0.0055 0.0033
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0419 0.1007
Brugia malayi jmjC domain containing protein 0.0017 0.0123 0.0114
Brugia malayi Calcitonin receptor-like protein seb-1 0.0054 0.0585 0.0577
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0428 0.1031
Schistosoma mansoni Tr4/Tr2 (homologue) 0.001 0.0034 0.003
Schistosoma mansoni cpg binding protein 0.0031 0.0306 0.0358
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0067 0.0756 0.0735
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Loa Loa (eye worm) hypothetical protein 0.0012 0.0064 0.0042
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.001 0.0034 0.0011
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0292 0.3589 1
Trypanosoma brucei DNA polymerase eta, putative 0.0039 0.0407 0.0971
Schistosoma mansoni phd/f-box containing protein 0.0017 0.0123 0.0137
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.1651 0.4502
Echinococcus multilocularis tumor susceptibility gene 101 protein 0.0076 0.0868 0.0866
Plasmodium falciparum importin beta, putative 0.0031 0.0301 0.9479
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0195 0.1939
Brugia malayi MH2 domain containing protein 0.013 0.1554 0.1546
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0034 0.0013
Brugia malayi Fli-1 protein 0.024 0.2937 0.293
Schistosoma mansoni DNA polymerase IV / kappa 0.0012 0.0064 0.0067
Entamoeba histolytica hypothetical protein 0.0013 0.0071 0.0491
Echinococcus granulosus microtubule associated protein 2 0.0667 0.8315 1
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.001 0.0034 0.0011
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0039 0.0407 0.0971
Schistosoma mansoni microtubule-associated protein tau 0.0667 0.8315 1
Echinococcus multilocularis ets variant gene 4 0.0011 0.0055 0.0033
Echinococcus granulosus lysine specific demethylase 5A 0.0069 0.0781 0.0915
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0317 0.374
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.001 0.0034 0.003
Echinococcus multilocularis ETS transcription factor Elf 1 0.0011 0.0055 0.0033
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0195 0.0371
Trypanosoma cruzi importin beta-1 subunit, putative 0.0025 0.0227 0.0461
Brugia malayi Muscleblind-like protein 0.0321 0.396 0.3955
Echinococcus multilocularis GA binding protein alpha chain 0.0079 0.0907 0.0906
Schistosoma mansoni hypothetical protein 0.0037 0.0372 0.0437
Brugia malayi DNA-binding protein D-ETS-3 0.0011 0.0055 0.0046
Brugia malayi serine/threonine-protein kinase plk-2 0.0103 0.1211 0.1203
Schistosoma mansoni beta-mannosidase 0.0051 0.0557 0.066
Echinococcus multilocularis muscleblind protein 0.0321 0.396 0.4033
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0195 0.0371
Entamoeba histolytica beta-galactosidase, putative 0.0107 0.1257 1
Echinococcus granulosus ecdysone induced protein 78C 0.001 0.0034 0.0013
Schistosoma mansoni hypothetical protein 0.0017 0.0124 0.0139
Echinococcus multilocularis L aminoadipate semialdehyde 0.008 0.0923 0.0922
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0033 0.0323 0.0308
Echinococcus granulosus geminin 0.0531 0.6599 0.7931
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0756 0.09
Onchocerca volvulus Bile acid receptor homolog 0.001 0.0034 0.0025
Schistosoma mansoni Smad4 0.0009 0.0022 0.0017
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0011
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0011 0.0048 0.003
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0011
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0407 0.0398
Schistosoma mansoni hypothetical protein 0.0011 0.0055 0.0056
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1211 0.3874
Echinococcus multilocularis microtubule associated protein 2 0.0667 0.8315 0.8493
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0055 0.0033
Brugia malayi jmjC domain containing protein 0.0017 0.0123 0.0114
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0123 0.0165
Entamoeba histolytica hypothetical protein 0.0039 0.0406 0.3176
Schistosoma mansoni RAR-like nuclear receptor 0.001 0.0034 0.003
Schistosoma mansoni hypothetical protein 0.0017 0.0124 0.0139
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0051 0.0548 0.065
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0011
Echinococcus multilocularis lysine specific demethylase 6a 0.0017 0.0123 0.0103
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0195 0.5
Brugia malayi Nuclear hormone receptor family member nhr-40 0.001 0.0034 0.0025
Echinococcus multilocularis isocitrate dehydrogenase 0.0032 0.0317 0.0301
Brugia malayi PHD-finger family protein 0.0056 0.0613 0.0605
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.1554 0.1535
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0756 0.09
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0106 0.1243 0.9883
Echinococcus multilocularis ETS transcription factor Elf 2 0.0011 0.0055 0.0033
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0034 0.0025
Brugia malayi manba-prov protein 0.0051 0.0557 0.0549
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0051 0.0548 0.0539
Plasmodium falciparum DNA repair protein REV1, putative 0.0012 0.0064 0.1796
Onchocerca volvulus Serine\/threonine kinase homolog 0.0103 0.1211 0.1203
Schistosoma mansoni tsg101-related 0.0063 0.0707 0.0841
Brugia malayi Isocitrate dehydrogenase 0.0032 0.0317 0.0308
Echinococcus granulosus histone lysine methyltransferase setb 0.007 0.0789 0.0924
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0039 0.0407 0.0463
Schistosoma mansoni hypothetical protein 0.0044 0.0462 0.0545
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0123 0.0101
Echinococcus granulosus importin subunit beta 1 0.0031 0.0301 0.0336
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.007 0.0789 0.0785
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1211 0.3874
Mycobacterium ulcerans hypothetical protein 0.0154 0.1848 0.232
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0103 0.1211 0.1433
Echinococcus granulosus muscleblind protein 0.0321 0.396 0.4749
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0032 0.0317 1
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1211 0.3874
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1211 0.3874
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0195 0.5
Echinococcus multilocularis geminin 0.0531 0.6599 0.6736
Entamoeba histolytica hypothetical protein 0.0025 0.0227 0.1744
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0407 0.0445
Echinococcus granulosus GA binding protein alpha chain 0.0079 0.0907 0.1067
Trichomonas vaginalis DNA polymerase eta, putative 0.0039 0.0407 0.1301
Echinococcus granulosus kelch ECH associated protein 1 like 0.0103 0.121 0.1433
Loa Loa (eye worm) beta-glucuronidase 0.0051 0.0557 0.0536
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0781 0.093
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0032 0.0317 0.0301
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0317 0.0716
Brugia malayi hypothetical protein 0.0076 0.0868 0.086
Brugia malayi ecdysteroid receptor 0.001 0.0034 0.0025
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Schistosoma mansoni hypothetical protein 0.0033 0.0328 0.0385
Loa Loa (eye worm) PHD-finger family protein 0.0045 0.0474 0.0452
Brugia malayi CHE-14 protein 0.0045 0.0482 0.0474
Schistosoma mansoni smad1 5 8 and 0.0009 0.0022 0.0017
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0054 0.0585 0.0564
Mycobacterium tuberculosis Probable isocitrate dehydrogenase [NADP] Icd1 (oxalosuccinate decarboxylase) (IDH) (NADP+-specific ICDH) (IDP) 0.0032 0.0317 0.0161
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0063 0.0706 0.07
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Echinococcus multilocularis ubiquitin carboxyl terminal hydrolase 8 0.004 0.0419 0.0407
Echinococcus multilocularis Niemann Pick C1 protein 0.0106 0.1243 0.125
Trichomonas vaginalis beta-galactosidase, putative 0.0158 0.1904 0.6093
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1211 0.3252
Brugia malayi Nuclear hormone receptor-like 1 0.001 0.0034 0.0025
Schistosoma mansoni patched 1 0.0045 0.0482 0.057
Echinococcus granulosus tumor susceptibility gene 101 protein 0.0076 0.0868 0.1019
Echinococcus granulosus dna polymerase eta 0.0039 0.0407 0.0463
Schistosoma mansoni kinase 0.0052 0.0571 0.0677
Schistosoma mansoni hypothetical protein 0.0011 0.0055 0.0056
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0195 0.1939
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0756 0.09
Schistosoma mansoni phosphatidylserine receptor 0.0017 0.0123 0.0137
Brugia malayi Ets-domain containing protein 0.0079 0.0907 0.0899
Brugia malayi Pre-SET motif family protein 0.0224 0.2735 0.2729
Brugia malayi Importin beta-1 subunit 0.0031 0.0301 0.0292
Mycobacterium leprae PROBABLE CONSERVED LIPOPROTEIN LPQF 0.007 0.0787 0.0783
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0033 0.0323 0.3835
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0034 0.0013
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0045 0.0482 0.0461
Brugia malayi Ubiquitin carboxyl-terminal hydrolase family protein 0.004 0.0419 0.0411
Trichomonas vaginalis conserved hypothetical protein 0.0158 0.1904 0.6093
Loa Loa (eye worm) hypothetical protein 0.0039 0.0407 0.0385
Plasmodium vivax SET domain protein, putative 0.0033 0.0323 1
Trypanosoma brucei polo-like protein kinase 0.0103 0.1211 0.3252
Echinococcus granulosus fetal alzheimer antigen falz 0.0051 0.0548 0.0634
Schistosoma mansoni polyomavirus enhancer activator 3 pea3 0.0011 0.0055 0.0056
Echinococcus multilocularis snurportin 1 0.033 0.4076 0.4152
Mycobacterium ulcerans UDP-galactopyranose mutase Glf 0.0622 0.7751 1
Giardia lamblia Kinase, PLK 0.0103 0.1211 1
Echinococcus granulosus expressed conserved protein 0.0099 0.1162 0.1374
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0124 0.0104
Trypanosoma cruzi DNA polymerase eta, putative 0.0039 0.0407 0.0971
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0124 0.0104
Toxoplasma gondii histone lysine methyltransferase SET1 0.0066 0.0739 1
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0032 0.0317 0.0716
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0078 0.0891 0.089
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0037 0.0376 0.0362
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0407 0.0971
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0011
Echinococcus multilocularis muscleblind protein 1 0.0321 0.396 0.4033
Schistosoma mansoni hypothetical protein 0.015 0.1801 0.2158
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0195 0.6051
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0023 0.0001
Onchocerca volvulus 0.08 1 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0124 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0045 0.0482 0.1543
Brugia malayi F/Y-rich N-terminus family protein 0.0015 0.0098 0.009
Brugia malayi Nuclear hormone receptor family member nhr-25 0.001 0.0034 0.0025
Echinococcus granulosus kelch ECH associated protein 1 like 0.0103 0.121 0.1433
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0317 0.0716
Leishmania major mitochondrial DNA polymerase beta 0.0292 0.3589 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.001 0.0034 0.0011
Echinococcus granulosus ubiquitin carboxyl terminal hydrolase 8 0.004 0.0419 0.0479
Mycobacterium leprae Probable UDP-galactopyranose mutase Glf (UDP-galp mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0622 0.7751 1
Schistosoma mansoni smad1 5 8 and 0.0009 0.0022 0.0017
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0039 0.0407 0.0385
Entamoeba histolytica hypothetical protein 0.0039 0.0406 0.3176
Loa Loa (eye worm) bromodomain containing protein 0.0038 0.0393 0.0371
Schistosoma mansoni hypothetical protein 0.0044 0.0462 0.0545
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.001 0.0034 0.0025
Brugia malayi jmjC domain containing protein 0.0069 0.0781 0.0773
Echinococcus granulosus ETS transcription factor Elf 5 0.0011 0.0055 0.0039
Trichomonas vaginalis conserved hypothetical protein 0.004 0.0419 0.1342
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0017 0.0123 0.0137
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0376 0.0442
Echinococcus granulosus methyl CpG binding domain protein 2 0.0037 0.0376 0.0426
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0253 0.0534
Entamoeba histolytica hypothetical protein 0.0023 0.0195 0.149
Schistosoma mansoni hypothetical protein 0.0017 0.0124 0.0139
Brugia malayi jmjC domain containing protein 0.0017 0.0123 0.0114
Echinococcus multilocularis cpg binding protein 0.0037 0.038 0.0367
Schistosoma mansoni retinoid-x-receptor (RXR) 0.001 0.0034 0.003
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0034 0.0025
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0406 0.0392
Trypanosoma brucei ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0419 0.1007
Schistosoma mansoni smad 0.0009 0.0022 0.0017
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0023 0.0001
Brugia malayi Nuclear hormone receptor family member nhr-31 0.001 0.0034 0.0025
Brugia malayi Smad1 0.0009 0.0022 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-1 0.001 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.0101
Echinococcus granulosus Niemann Pick C1 protein 0.0106 0.1243 0.1472
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0011
Echinococcus multilocularis phd:f box containing protein 0.0017 0.0123 0.0103
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0017 0.0123 0.0864
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0301 0.067
Schistosoma mansoni myst-related protein 0.0008 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0153 0.1841 0.1823
Onchocerca volvulus 0.0255 0.3124 0.3119
Entamoeba histolytica hypothetical protein 0.0013 0.0071 0.0491
Schistosoma mansoni coup transcription factor 0.001 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.004 0.0419 0.0398
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.001 0.0034 0.0013
Mycobacterium ulcerans lipoprotein LpqF 0.007 0.0787 0.094
Trypanosoma cruzi polo-like protein kinase, putative 0.0103 0.1211 0.3252
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0078 0.0891 0.1048
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0103 0.1211 0.3252
Schistosoma mansoni hypothetical protein 0.0447 0.554 0.666
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0407 0.0971
Leishmania major DNA polymerase eta, putative 0.0039 0.0407 0.0971
Echinococcus granulosus sterol regulatory element binding protein 0.0045 0.0482 0.0554
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0023 0.0197 0.0179
Schistosoma mansoni thyroid hormone receptor 0.001 0.0034 0.003
Brugia malayi Pre-SET motif family protein 0.0033 0.0323 0.0315
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0071 0.0226
Loa Loa (eye worm) hypothetical protein 0.08 1 1
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0124 0.0115
Schistosoma mansoni bromodomain containing protein 0.0139 0.166 0.1988
Entamoeba histolytica hypothetical protein 0.0013 0.0071 0.0491
Schistosoma mansoni retinoic acid receptor RXR 0.001 0.0034 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1211 0.3874
Trichomonas vaginalis hypothetical protein 0.0037 0.0377 0.1205
Trypanosoma brucei DNA polymerase IV, putative 0.0039 0.0407 0.0971
Schistosoma mansoni hypothetical protein 0.0017 0.0124 0.0139
Trichomonas vaginalis importin beta-1, putative 0.0025 0.0227 0.0726
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0031 0.03 0.0334
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0033 0.0323 0.0379
Echinococcus granulosus L aminoadipate semialdehyde 0.008 0.0923 0.1086
Brugia malayi MH1 domain containing protein 0.0009 0.0022 0.0014
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0789 0.0939
Echinococcus multilocularis dna polymerase kappa 0.0039 0.0407 0.0394
Echinococcus granulosus Niemann Pick C1 protein 0.0151 0.1814 0.2161
Echinococcus multilocularis dnaJ subfamily B 0.0447 0.554 0.5651
Schistosoma mansoni elf1 0.0011 0.0055 0.0056
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.001 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0011
Mycobacterium ulcerans DNA polymerase IV 0.0039 0.0407 0.0445
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0079 0.0907 0.0887
Echinococcus granulosus snurportin 1 0.033 0.4076 0.4888
Loa Loa (eye worm) hypothetical protein 0.0011 0.0055 0.0033
Echinococcus multilocularis Kelch repeat type 1 0.0103 0.1214 0.122
Echinococcus multilocularis protein C ets 2 0.0011 0.0055 0.0033
Echinococcus multilocularis tar DNA binding protein 0.0067 0.0756 0.0751
Schistosoma mansoni terminal deoxycytidyl transferase 0.0039 0.0407 0.0479
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0039 0.0407 0.0394
Loa Loa (eye worm) hypothetical protein 0.0321 0.396 0.3947
Brugia malayi hypothetical protein 0.0039 0.0406 0.0397
Brugia malayi Glycosyl hydrolases family 2, sugar binding domain containing protein 0.0056 0.0611 0.0603
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.001 0.0034 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1211 0.3874
Brugia malayi jmjC domain containing protein 0.0063 0.0706 0.0698
Brugia malayi Ets-domain containing protein 0.0011 0.0055 0.0046
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0039 0.0407 0.1301
Schistosoma mansoni ubiquitin-specific peptidase 2 (C19 family) 0.004 0.0419 0.0495
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0195 0.5058
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0103 0.1211 0.1217
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0039 0.0407 0.028
Echinococcus granulosus phd:f box containing protein 0.0017 0.0123 0.0121
Loa Loa (eye worm) ets-domain-containing protein 0.0011 0.0055 0.0033
Loa Loa (eye worm) steroid hormone receptor 0.001 0.0034 0.0011
Loa Loa (eye worm) RNA binding protein 0.0067 0.0756 0.0735
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0032 0.0317 0.0716
Echinococcus granulosus ewsr:fli fusion protein type 0.0011 0.0055 0.0039
Echinococcus multilocularis Niemann Pick C1 protein 0.0151 0.1814 0.1835
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0131 0.1563 0.1857
Entamoeba histolytica deoxycytidyl transferase, putative 0.0039 0.0407 0.3184
Schistosoma mansoni tsg101-related 0.0063 0.0707 0.0841
Schistosoma mansoni bromodomain containing protein 0.0011 0.005 0.005
Brugia malayi latrophilin 2 splice variant baaae 0.0037 0.0372 0.0363
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0063 0.0706 0.0825
Schistosoma mansoni myst-related protein 0.0008 0.0009 0.0001
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Schistosoma mansoni jumonji domain containing protein 0.0017 0.0123 0.0137
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0195 0.017
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0032 0.0317 0.0355
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0071 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.001 0.0034 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-14 0.001 0.0034 0.0025
Plasmodium vivax JmjC domain containing protein 0.0017 0.0123 0.2252
Schistosoma mansoni hypothetical protein 0.0531 0.6599 0.7935
Trypanosoma brucei Vps23 core domain containing protein, putative 0.0024 0.0217 0.0432
Trypanosoma brucei unspecified product 0.0027 0.0253 0.0534
Brugia malayi TAR-binding protein 0.0067 0.0756 0.0748
Brugia malayi transcription factor E74 isoform 0.0011 0.0055 0.0046
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0227 0.0726
Brugia malayi Bromodomain containing protein 0.0164 0.198 0.1973
Brugia malayi MH1 domain containing protein 0.0009 0.0022 0.0014
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0317 0.0301
Echinococcus multilocularis dna polymerase eta 0.0039 0.0407 0.0394
Leishmania major importin beta-1 subunit, putative 0.0025 0.0227 0.0461
Loa Loa (eye worm) hypothetical protein 0.0056 0.0611 0.059
Schistosoma mansoni hypothetical protein 0.0045 0.0474 0.056
Loa Loa (eye worm) hypothetical protein 0.0017 0.0124 0.0102
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0317 0.0301
Schistosoma mansoni gabp alpha 0.0079 0.0907 0.1082
Echinococcus multilocularis Peptidase C19, ubiquitin carboxyl terminal hydrolase 2 0.004 0.0419 0.0407
Brugia malayi Steroid receptor seven-up type 2 0.001 0.0034 0.0025
Brugia malayi RNA recognition motif domain containing protein 0.0067 0.0756 0.0748
Loa Loa (eye worm) histone methyltransferase 0.0011 0.0048 0.0025
Leishmania major ubiquitin hydrolase, putative,cysteine peptidase, Clan CA, family C19, putative 0.004 0.0419 0.1007
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.033 0.4076 0.4063
Toxoplasma gondii isocitrate dehydrogenase 0.0032 0.0317 0.374
Entamoeba histolytica hypothetical protein 0.0013 0.0071 0.0491
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0419 0.1342
Schistosoma mansoni importin beta-1 0.0031 0.0301 0.0352
Echinococcus granulosus dna polymerase kappa 0.0039 0.0407 0.0463
Echinococcus granulosus zinc finger protein 0.0044 0.0467 0.0537
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.007 0.0789 0.0939
Echinococcus multilocularis jumonji domain containing 1A 0.0017 0.0123 0.0103
Trypanosoma brucei unspecified product 0.0027 0.0253 0.0534
Toxoplasma gondii hypothetical protein 0.0047 0.0504 0.6514
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0253 0.0534
Trichomonas vaginalis set domain proteins, putative 0.0255 0.3124 1
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Echinococcus multilocularis protein dispatched 1 0.0052 0.0563 0.0554
Schistosoma mansoni tsg101-related 0.0052 0.0561 0.0666
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0034 0.0011
Loa Loa (eye worm) glycosyl hydrolase family 2 0.0056 0.0611 0.059
Onchocerca volvulus 0.0033 0.0323 0.0315
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0009 0.0022 0.0017
Echinococcus multilocularis ETS domain containing protein Elk 1 0.0011 0.0055 0.0033
Brugia malayi Beta-glucuronidase precursor 0.0051 0.0557 0.0549
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0292 0.3589 1
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0041 0.0428 0.1031
Loa Loa (eye worm) hypothetical protein 0.0083 0.0958 0.0937
Toxoplasma gondii HEAT repeat-containing protein 0.0031 0.0301 0.3502
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Loa Loa (eye worm) jmjC domain-containing protein 0.0069 0.0781 0.076
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Loa Loa (eye worm) hypothetical protein 0.008 0.0923 0.0903
Echinococcus multilocularis JmjC domain containing protein 4 0.0017 0.0123 0.0103
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0023 0.0197 0.0211
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0032 0.0317 0.0371
Schistosoma mansoni protein phosphatase 2C 0.0017 0.0123 0.0137
Brugia malayi jmjC domain containing protein 0.0017 0.0123 0.0114
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0138 0.1651 0.4502
Echinococcus granulosus protein C ets 2 0.0011 0.0055 0.0039
Plasmodium vivax importin-beta 2, putative 0.0031 0.0301 0.9134
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0017 0.0123 0.0165
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0124 0.0102
Giardia lamblia DINP protein human, muc B family 0.0039 0.0407 0.2986
Schistosoma mansoni zinc finger protein 0.0033 0.0328 0.0385
Leishmania major hypothetical protein, conserved 0.0033 0.0328 0.0748
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0032 0.0317 0.9753
Schistosoma mansoni serine/threonine protein kinase 0.0103 0.1211 0.1447
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.001 0.0034 0.003
Schistosoma mansoni jumonji/arid domain-containing protein 0.0069 0.0781 0.093
Loa Loa (eye worm) hypothetical protein 0.007 0.0789 0.0768
Leishmania major DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0224 0.2735 0.2719
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.008 0.0923 0.0915
Trichomonas vaginalis CAMK family protein kinase 0.0103 0.1211 0.3874
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0138 0.1651 0.4502
Schistosoma mansoni ets-related 0.024 0.2937 0.3525
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0124 0.0122
Mycobacterium tuberculosis Probable conserved lipoprotein LpqF 0.007 0.0787 0.0783
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Echinococcus multilocularis protein patched 0.0045 0.0482 0.0471
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0055 0.0039
Trypanosoma cruzi hypothetical protein, conserved 0.0013 0.0071 0.0017
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0041 0.0428 0.1031
Loa Loa (eye worm) hypothetical protein 0.0031 0.0301 0.0279
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0054 0.0585 0.0577
Echinococcus granulosus jumonji domain containing 1A 0.0017 0.0123 0.0121
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0034 0.0025
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0025 0.0227 0.0726
Echinococcus multilocularis ewsr:fli fusion protein type 0.0011 0.0055 0.0033
Brugia malayi ImpB/MucB/SamB family protein 0.0039 0.0407 0.0398
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Trypanosoma brucei UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Schistosoma mansoni hypothetical protein 0.0039 0.0406 0.0478
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0124 0.0115
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0033 0.0323 0.0379
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.001 0.0034 0.0011
Loa Loa (eye worm) hypothetical protein 0.0094 0.1097 0.1077
Echinococcus multilocularis importin subunit beta 1 0.0031 0.0301 0.0285
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Trypanosoma cruzi ubiquitin carboxyl-terminal hydrolase, putative 0.004 0.0419 0.1007
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0039 0.0407 0.0479
Loa Loa (eye worm) hypothetical protein 0.0045 0.0482 0.0461
Loa Loa (eye worm) hypothetical protein 0.0011 0.005 0.0027
Brugia malayi Nuclear hormone receptor family member nhr-3 0.001 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0321 0.396 0.3947
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0195 0.5
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0554 0.1773
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0011 0.0055 0.0033
Echinococcus multilocularis kelch ECH associated protein 1 0.0103 0.121 0.1217
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0756 0.09
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.001 0.0034 0.003
Trypanosoma cruzi DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Brugia malayi Nuclear hormone receptor family member nhr-41 0.001 0.0034 0.0025
Echinococcus granulosus ETS transcription factor Elf 1 0.0011 0.0055 0.0039
Plasmodium falciparum JmjC domain-containing protein, putative 0.0017 0.0123 0.369
Schistosoma mansoni nuclear hormone receptor 0.001 0.0034 0.003
Trichomonas vaginalis CAMK family protein kinase 0.0051 0.0554 0.1773
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0009 0.0023 0.0018
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.0101
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0017 0.0123 0.0864
Schistosoma mansoni hypothetical protein 0.033 0.4076 0.4897
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.001 0.0034 0.0013
Schistosoma mansoni ets 0.0011 0.0055 0.0056
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Echinococcus granulosus Protein patched homolog 1 0.0045 0.0482 0.0554
Echinococcus multilocularis sterol regulatory element binding protein 0.0045 0.0482 0.0471
Onchocerca volvulus 0.0031 0.0306 0.0297
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0123 0.0101
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0017 0.0123 0.0165
Brugia malayi nuclear hormone receptor 0.001 0.0034 0.0025
Echinococcus multilocularis thyroid hormone receptor alpha 0.001 0.0034 0.0011
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.0428 0.1031
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0011 0.0048 0.0026
Brugia malayi Bromodomain containing protein 0.0083 0.0956 0.0948
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.005 0.0541 0.1352
Brugia malayi RNA binding protein 0.0067 0.0756 0.0748
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.001 0.0034 0.0011
Schistosoma mansoni DNA polymerase eta 0.0039 0.0407 0.0479
Entamoeba histolytica hypothetical protein 0.0039 0.0406 0.3176
Trichomonas vaginalis Clan CA, family C19, ubiquitin hydrolase-like cysteine peptidase 0.004 0.0419 0.1342
Brugia malayi Nuclear hormone receptor family member nhr-49 0.001 0.0034 0.0025
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0068 0.0764 0.0909
Trypanosoma brucei DNA polymerase kappa, putative 0.0039 0.0407 0.0971
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.008 0.0923 0.1101
Echinococcus granulosus lysine specific demethylase 6a 0.0017 0.0123 0.0121
Brugia malayi MH2 domain containing protein 0.0009 0.0022 0.0014
Schistosoma mansoni ubiquitin-specific peptidase 8 (C19 family) 0.004 0.0419 0.0495
Loa Loa (eye worm) hypothetical protein 0.0054 0.0585 0.0564
Giardia lamblia Ubiquitin carboxyl-terminal hydrolase 4 0.004 0.0419 0.3097
Mycobacterium ulcerans class a beta-lactamase, BlaC 0.0145 0.1737 0.2176
Leishmania major hypothetical protein, conserved 0.0017 0.0123 0.0165
Trypanosoma brucei beta lactamase 0.007 0.0787 0.2051
Schistosoma mansoni hypothetical protein 0.0044 0.0462 0.0545
Loa Loa (eye worm) hypothetical protein 0.0068 0.0763 0.0742
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.001 0.0034 0.0011
Trypanosoma cruzi ISWI complex protein 0.0033 0.0328 0.0748
Schistosoma mansoni tar DNA-binding protein 0.0067 0.0756 0.09
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.001 0.0034 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0027 0.0253 0.0534
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.001 0.0034 0.0011
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0103 0.1211 0.1191
Mycobacterium tuberculosis Conserved hypothetical protein 0.0154 0.1848 0.2187
Trypanosoma brucei unspecified product 0.0039 0.0407 0.0971
Echinococcus multilocularis ETS transcription factor Elf 5 0.0011 0.0055 0.0033
Echinococcus multilocularis zinc finger protein 0.0044 0.0467 0.0456
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0032 0.0317 0.0716
Schistosoma mansoni methyl-cpg binding protein mbd 0.0037 0.0376 0.0442
Brugia malayi Ets-domain containing protein 0.0079 0.0907 0.0899
Brugia malayi Nuclear hormone receptor family member nhr-19 0.001 0.0034 0.0025
Trypanosoma cruzi Vps23 core domain containing protein, putative 0.0024 0.0217 0.0432
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.001 0.0034 0.0011
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0107 0.1263 0.1511
Trichomonas vaginalis glycoside hydrolase, putative 0.0253 0.3094 0.9904
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0783 0.9786 1
Echinococcus granulosus ubiquitin specific protease 41 0.004 0.0419 0.0479
Schistosoma mansoni cpg binding protein 0.0037 0.038 0.0448
Brugia malayi isocitrate dehydrogenase 0.0032 0.0317 0.0308
Entamoeba histolytica hypothetical protein 0.0039 0.0406 0.3176
Mycobacterium tuberculosis Class a beta-lactamase BlaC 0.0145 0.1737 0.2041
Loa Loa (eye worm) fli-1 protein 0.024 0.2937 0.2921
Schistosoma mansoni cpg binding protein 0.0037 0.038 0.0448
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0406 0.0478
Echinococcus granulosus kelch ECH associated protein 1 0.0103 0.121 0.1433
Echinococcus granulosus JmjC domain containing protein 4 0.0017 0.0123 0.0121
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0032 0.0317 0.0301
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0195 0.017
Mycobacterium tuberculosis Conserved hypothetical protein 0.0039 0.0407 0.028
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0009 0.0023 0.0001
Echinococcus multilocularis FTZ F1 alpha 0.001 0.0034 0.0011
Schistosoma mansoni ets-related 0.0011 0.0055 0.0056
Brugia malayi MH2 domain containing protein 0.0009 0.0022 0.0014
Schistosoma mansoni thyroid hormone receptor 0.001 0.0034 0.003
Loa Loa (eye worm) hypothetical protein 0.001 0.0034 0.0011
Loa Loa (eye worm) hypothetical protein 0.0088 0.1022 0.1002
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0306 0.0284
Loa Loa (eye worm) D-ets-2 protein 0.0011 0.0055 0.0033
Echinococcus multilocularis GPCR, family 2 0.0017 0.0124 0.0104
Loa Loa (eye worm) hypothetical protein 0.0011 0.0055 0.0033
Echinococcus granulosus ETS domain containing protein Elk 1 0.0011 0.0055 0.0039
Entamoeba histolytica ubiquitin carboxyl-terminal hydrolase domain containing protein 0.004 0.0419 0.3287
Brugia malayi RNA, U transporter 1 0.0088 0.102 0.1012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0123 0.0101
Echinococcus granulosus ETS transcription factor Elf 2 0.0011 0.0055 0.0039
Trypanosoma cruzi UEV domain/Zinc finger, C3HC4 type (RING finger), putative 0.0013 0.0071 0.0017
Brugia malayi CXXC zinc finger family protein 0.0031 0.0306 0.0297
Schistosoma mansoni hypothetical protein 0.0531 0.6599 0.7935
Brugia malayi Niemann-Pick C1 protein precursor 0.0106 0.1243 0.1235
Brugia malayi photoreceptor-specific nuclear receptor 0.001 0.0034 0.0025
Schistosoma mansoni jumonji domain containing protein 0.0063 0.0706 0.084
Onchocerca volvulus Protein ultraspiracle homolog 0.001 0.0034 0.0025
Trichomonas vaginalis beta-mannosidase, putative 0.0051 0.0557 0.1782
Trypanosoma cruzi ISWI complex protein 0.0033 0.0328 0.0748
Brugia malayi nuclear receptor NHR-88 0.001 0.0034 0.0025
Trichomonas vaginalis conserved hypothetical protein 0.0013 0.0071 0.0226
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.001 0.0034 0.0025
Echinococcus multilocularis expressed conserved protein 0.0099 0.1162 0.1167
Echinococcus granulosus mixed lineage leukemia protein mll 0.0009 0.0023 0.0001
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0406 0.0462
Trypanosoma brucei importin beta-1 subunit, putative 0.0031 0.0301 0.067
Schistosoma mansoni smad1 5 8 and 0.0009 0.0022 0.0017
Leishmania major hypothetical protein, conserved 0.0024 0.0217 0.0432
Mycobacterium tuberculosis UDP-galactopyranose mutase Glf (UDP-GALP mutase) (NAD+-flavin adenine dinucleotide-requiring enzyme) 0.0622 0.7751 1
Echinococcus multilocularis ubiquitin specific protease 41 0.004 0.0419 0.0407
Schistosoma mansoni hypothetical protein 0.0044 0.0462 0.0545
Echinococcus multilocularis kelch ECH associated protein 1 0.0103 0.121 0.1217
Trypanosoma brucei ISWI complex protein 0.0033 0.0328 0.0748
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0034 0.0011
Onchocerca volvulus 0.001 0.0034 0.0025
Loa Loa (eye worm) hypothetical protein 0.0106 0.1243 0.1223
Entamoeba histolytica tumor susceptibility gene 101 protein, putative 0.0052 0.0561 0.4425
Schistosoma mansoni steroid hormone receptor ad4bp 0.001 0.0034 0.003
Brugia malayi polk-prov protein 0.0012 0.0064 0.0056
Echinococcus granulosus tar DNA binding protein 0.0067 0.0756 0.0885
Onchocerca volvulus 0.008 0.0923 0.0915
Loa Loa (eye worm) TAR-binding protein 0.0067 0.0756 0.0735
Echinococcus granulosus retinoic acid receptor rxr beta a 0.001 0.0034 0.0013
Loa Loa (eye worm) isocitrate dehydrogenase 0.0032 0.0317 0.0295
Schistosoma mansoni zinc finger protein 0.0044 0.0467 0.0552
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.1554 0.1535
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0131 0.1563 0.1577
Loa Loa (eye worm) jmjC domain-containing protein 0.0017 0.0123 0.0101
Loa Loa (eye worm) hypothetical protein 0.0076 0.0868 0.0847

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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