Detailed information for compound 832726

Basic information

Technical information
  • TDR Targets ID: 832726
  • Name: [3-(benzoyl)-1,1-dioxo-2-propylbenzo[e]thiazi n-4-yl] benzoate
  • MW: 447.503 | Formula: C25H21NO5S
  • H donors: 0 H acceptors: 4 LogP: 4.78 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCN1C(=C(OC(=O)c2ccccc2)c2c(S1(=O)=O)cccc2)C(=O)c1ccccc1
  • InChi: 1S/C25H21NO5S/c1-2-17-26-22(23(27)18-11-5-3-6-12-18)24(31-25(28)19-13-7-4-8-14-19)20-15-9-10-16-21(20)32(26,29)30/h3-16H,2,17H2,1H3
  • InChiKey: XFXZQUGCMYJMQT-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • [3-(benzoyl)-1,1-dioxo-2-propyl-benzo[e]thiazin-4-yl] benzoate
  • benzoic acid [1,1-dioxo-3-(oxo-phenylmethyl)-2-propyl-4-benzo[e]thiazinyl] ester
  • benzoic acid [3-(benzoyl)-1,1-diketo-2-propyl-benzo[e]thiazin-4-yl] ester
  • (1,1-dioxo-3-phenylcarbonyl-2-propyl-benzo[e][1,2]thiazin-4-yl) benzoate

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0043 0.014
Schistosoma mansoni alpha-1 adrenergic receptor 0.0012 0.0047 0.0063
Mycobacterium leprae Possible lysyl-tRNA synthetase 2 LysX 0.0049 0.045 0.6932
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1969 0.6471
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.045 1
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0656 0.2157
Echinococcus multilocularis Threonyl tRNA synthetase, C 0.0012 0.0053 0.0063
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0175 0.2315
Echinococcus multilocularis G protein coupled receptor 139 0.0012 0.0047 0.0055
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Brugia malayi beta-lactamase 0.0036 0.0308 0.0407
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0047 0.0063
Schistosoma mansoni ap endonuclease 0.0019 0.0126 0.0169
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus multilocularis Chromo domain 0.0011 0.0043 0.005
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0126 0.1677
Echinococcus granulosus TGF beta signal transducer SmadC 0.0008 0.0007 0.001
Mycobacterium leprae Probable lysyl-tRNA synthase LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.037 0.5587
Loa Loa (eye worm) hypothetical protein 0.0036 0.0308 0.0417
Onchocerca volvulus 0.0011 0.0043 0.0004
Schistosoma mansoni sugar transporter 0.0031 0.0254 0.0341
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Echinococcus multilocularis serotonin receptor 0.0012 0.0047 0.0055
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0308 0.4105
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0126 0.1677
Loa Loa (eye worm) MH2 domain-containing protein 0.0008 0.0007 0.001
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0067 0.0647 0.0647
Loa Loa (eye worm) hypothetical protein 0.0036 0.0308 0.0417
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0308 0.4546
Brugia malayi Tachykinin-like peptides receptor 99D 0.0012 0.0047 0.0053
Brugia malayi larval opioid receptor 0.0012 0.0047 0.0053
Echinococcus multilocularis serotonin receptor 0.0012 0.0047 0.0055
Schistosoma mansoni neuropeptide receptor 0.0012 0.0047 0.0063
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0113 0.0371
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Schistosoma mansoni survival motor neuron protein 0.0047 0.043 0.0577
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Plasmodium vivax heterochromatin protein 1, putative 0.0011 0.0043 0.0043
Loa Loa (eye worm) doublecortin family protein 0.002 0.0132 0.0179
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0012 0.0047 0.0053
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0012 0.0047 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.022 0.2295 0.7543
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2079 0.6833
Trypanosoma brucei glucose transporter, putative 0.0068 0.0656 0.8747
Echinococcus multilocularis solute carrier family 22 0.0031 0.0254 0.0299
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0577 0.0775
Onchocerca volvulus 0.0047 0.043 0.2014
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0067 0.0647 0.0876
Trichomonas vaginalis CAMK family protein kinase 0.0067 0.0647 0.2127
Entamoeba histolytica threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0129
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0179
Loa Loa (eye worm) hypothetical protein 0.0011 0.0043 0.0058
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Brugia malayi M-phase phosphoprotein, mpp8 0.0011 0.0043 0.0048
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0042 0.0056
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.0055
Leishmania major glucose transporter, lmgt3 0.0068 0.0656 0.8747
Plasmodium vivax glycine--tRNA ligase, putative 0.0012 0.0053 0.0053
Schistosoma mansoni nuclear transcription factor X-box binding 1 (nfx1) 0.0031 0.0254 0.0341
Trypanosoma brucei glucose transporter, putative 0.0068 0.0656 0.8747
Plasmodium falciparum calcium-dependent protein kinase 2 0.0067 0.0647 0.0647
Schistosoma mansoni histamine h1 receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.015
Schistosoma mansoni hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi Cam kinase protein 1 0.0067 0.0647 0.0867
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0656 0.2157
Onchocerca volvulus 0.0012 0.0047 0.0024
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0047 0.0055
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0175 0.39
Onchocerca volvulus 0.0031 0.0254 0.1099
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0057
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0175 0.0425
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0656 0.8747
Plasmodium vivax calcium-dependent protein kinase, putative 0.0067 0.0647 0.0647
Echinococcus granulosus chromobox protein 2 0.0011 0.0043 0.0057
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0111 0.2463
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Brugia malayi sulfakinin receptor protein 0.0012 0.0047 0.0053
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0012 0.0047 0.0053
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0012 0.0047 0.0024
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0175 0.39
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.006 0.0071
Toxoplasma gondii exonuclease III APE 0.0019 0.0126 0.019
Echinococcus multilocularis cpg binding protein 0.003 0.0247 0.0291
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0043 0.0043
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0042 0.0049
Schistosoma mansoni neuropeptide receptor 0.0012 0.0047 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Loa Loa (eye worm) sugar transporter 0.0031 0.0254 0.0344
Schistosoma mansoni glucose transport protein 0.022 0.2295 0.3082
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0057
Echinococcus granulosus chromobox protein 1 0.0069 0.0671 0.0901
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0113 0.0371
Onchocerca volvulus 0.0012 0.0047 0.0024
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0308 0.1013
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus granulosus tachykinin peptides receptor 99D 0.0012 0.0047 0.0063
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.0055
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus granulosus allatostatin A receptor 0.0012 0.0047 0.0063
Echinococcus multilocularis solute carrier family 22 0.0031 0.0254 0.0299
Trypanosoma brucei glucose transporter, putative 0.0068 0.0656 0.8747
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0047 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0042 0.0047
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0063
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.0761
Plasmodium falciparum calcium-dependent protein kinase 4 0.0067 0.0647 0.0647
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0373 0.1718
Toxoplasma gondii YbaK/proline-tRNA ligase associated domain-containing protein 0.0011 0.0038 0.0057
Chlamydia trachomatis proline--tRNA ligase 0.0023 0.0171 0.3811
Loa Loa (eye worm) hypothetical protein 0.0054 0.0499 0.0675
Onchocerca volvulus 0.0029 0.0229 0.0973
Echinococcus multilocularis calcium dependent protein kinase 0.0063 0.0602 0.0709
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0175 0.39
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0308 0.1144
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0126 0.0373
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0308 0.1144
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0341 0.1121
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Schistosoma mansoni glucose transport protein 0.022 0.2295 0.3082
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0132 0.0156
Toxoplasma gondii threonyl-tRNA synthetase family protein 0.0012 0.0053 0.008
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0308 0.6848
Brugia malayi Sugar transporter family protein 0.0031 0.0254 0.0334
Schistosoma mansoni hypothetical protein 0.0408 0.4331 0.5817
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0012 0.0047 0.0063
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0063
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0043 0.0064
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Onchocerca volvulus 0.0012 0.0047 0.0024
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0124
Plasmodium falciparum lysine--tRNA ligase 0.0049 0.045 0.045
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0043 0.0057
Onchocerca volvulus 0.0031 0.0254 0.1099
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0175 0.39
Echinococcus multilocularis RUN 0.002 0.0132 0.0156
Echinococcus granulosus solute carrier family 22 0.0031 0.0254 0.0341
Onchocerca volvulus 0.002 0.0132 0.0469
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Toxoplasma gondii protein kinase, putative 0.062 0.663 1
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.3042 1
Onchocerca volvulus 0.0031 0.0254 0.1099
Loa Loa (eye worm) sugar transporter 0.022 0.2295 0.3108
Loa Loa (eye worm) hypothetical protein 0.0139 0.1419 0.1921
Loa Loa (eye worm) hypothetical protein 0.0031 0.025 0.0338
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0067 0.0647 0.0869
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0047 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0042 0.0047
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Leishmania major glucose transporter, lmgt1 0.0068 0.0656 0.8747
Trichomonas vaginalis conserved hypothetical protein 0.0039 0.0341 0.1121
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.0055
Entamoeba histolytica DNA repair and recombination protein RAD52, putative 0.0388 0.4123 1
Brugia malayi latrophilin 2 splice variant baaae 0.0139 0.1419 0.1913
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0057
Leishmania major threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Onchocerca volvulus 0.0031 0.0254 0.1099
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.0055
Brugia malayi G-protein coupled receptor 0.0012 0.0047 0.0053
Echinococcus granulosus smad 0.0008 0.0007 0.001
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0043 0.0043
Trypanosoma brucei glucose transporter, putative 0.0068 0.0656 0.8747
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0038 0.0504
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1969 0.6471
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0043 0.014
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Mycobacterium tuberculosis Conserved protein 0.0036 0.0308 0.1144
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.0834
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.0761
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0042 0.0057
Giardia lamblia DNA repair protein RAD52 0.0388 0.4123 1
Schistosoma mansoni chromobox protein 0.0011 0.0043 0.0057
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0047 0.0063
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0656 0.8747
Trypanosoma brucei glucose transporter 1E 0.0068 0.0656 0.8747
Brugia malayi RE15519p 0.0012 0.0047 0.0053
Onchocerca volvulus Putative transporter 0.0031 0.0254 0.1099
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0254 0.0344
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.3042 1
Trypanosoma cruzi glucose transporter, putative 0.0031 0.0254 0.3381
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0289 0.3042 0.412
Echinococcus granulosus g-protein coupled receptor 0.0012 0.0047 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0042 0.0047
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0008 0.0007 0.001
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0656 0.2157
Trichomonas vaginalis Heterochromatin protein, putative 0.0011 0.0043 0.014
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.014
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0009 0.0016 0.0018
Onchocerca volvulus 0.0036 0.0308 0.1381
Trichomonas vaginalis chromobox protein, putative 0.0011 0.0043 0.014
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0064 0.0614 0.0822
Trypanosoma cruzi threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0504
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0042 0.0056
Echinococcus multilocularis somatostatin receptor 0.0012 0.0047 0.0055
Wolbachia endosymbiont of Brugia malayi major facilitator superfamily permease 0.0031 0.0254 1
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0075 0.0247
Schistosoma mansoni biogenic amine (5HT) receptor 0.0012 0.0047 0.0063
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.075 1
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0656 0.2157
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0011 0.0043 0.0048
Brugia malayi CHD4 protein 0.0013 0.006 0.0072
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.014
Leishmania major glucose transporter, lmgt2 0.0068 0.0656 0.8747
Mycobacterium ulcerans threonyl-tRNA synthetase 0.0012 0.0053 0.1186
Brugia malayi threonyl-tRNA synthetase, cytoplasmic 0.0012 0.0053 0.0062
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0047 0.0055
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0671 0.2206
Brugia malayi hypothetical protein 0.0031 0.0254 0.0334
Brugia malayi Serotonin receptor 0.0012 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0421 0.0565
Giardia lamblia Hexose transporter 0.0031 0.0254 0.0492
Brugia malayi major facilitator superfamily protein 0.0031 0.0254 0.0334
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0042 0.0056
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0042 0.0057
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0011 0.0043 0.0057
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0064 0.0614 0.0824
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0126 0.2797
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0126 0.0169
Plasmodium vivax CDK-related protein kinase 6, putative 0.0932 1 1
Echinococcus multilocularis neuropeptide receptor A26 0.0012 0.0047 0.0055
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0064 0.0614 0.0722
Echinococcus multilocularis Sugar transporter ERD6 protein 0.0031 0.0254 0.0299
Echinococcus multilocularis dnaJ subfamily B 0.0408 0.4331 0.5097
Schistosoma mansoni cpg binding protein 0.003 0.0247 0.0332
Brugia malayi beta-lactamase family protein 0.0036 0.0308 0.0407
Brugia malayi Sugar transporter family protein 0.0031 0.0254 0.0334
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.3042 1
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0047 0.0055
Trypanosoma cruzi lysyl-tRNA synthetase, putative 0.0049 0.045 0.5996
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0308 0.0407
Schistosoma mansoni hypothetical protein 0.0022 0.0156 0.0209
Toxoplasma gondii ABC1 family protein 0.0036 0.0308 0.0465
Loa Loa (eye worm) TYRA-2 protein 0.0012 0.0047 0.0063
Leishmania major hypothetical protein, conserved 0.0036 0.0308 0.4105
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Schistosoma mansoni neuropeptide receptor 0.0012 0.0047 0.0063
Echinococcus multilocularis smad 0.0008 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Trichomonas vaginalis hypothetical protein 0.0011 0.0043 0.014
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0042 0.0056
Entamoeba histolytica hypothetical protein 0.0011 0.0043 0.0104
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0012 0.0049 0.0066
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0067 0.0647 0.0976
Echinococcus granulosus RUN 0.002 0.0132 0.0178
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Trypanosoma cruzi Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0504
Loa Loa (eye worm) hypothetical protein 0.0024 0.0175 0.0238
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0042 0.0047
Giardia lamblia Prolyl-tRNA synthetase 0.0066 0.0632 0.1422
Mycobacterium tuberculosis Probable dicarboxylic acid transport integral membrane protein KgtP (dicarboxylate transporter) 0.0031 0.0254 0.0914
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0042 0.0047
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0046 0.0421 0.0561
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Loa Loa (eye worm) hypothetical protein 0.0039 0.0341 0.0462
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.0761
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0175 0.0582
Echinococcus granulosus g protein coupled receptor 0.0012 0.0047 0.0063
Schistosoma mansoni loxhd1 0.002 0.0132 0.0178
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0012 0.0047 0.0063
Schistosoma mansoni smad1 5 8 and 0.0008 0.0007 0.001
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0042 0.0049
Echinococcus granulosus orexin receptor type 2 0.0012 0.0047 0.0063
Toxoplasma gondii sugar transporter ST3 0.0031 0.0254 0.0383
Onchocerca volvulus 0.0036 0.0308 0.1381
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.075 1
Echinococcus granulosus G protein coupled receptor 139 0.0012 0.0047 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0042 0.0047
Echinococcus granulosus mothers against decapentaplegic 5 0.0008 0.0007 0.001
Plasmodium falciparum threonine--tRNA ligase 0.0012 0.0053 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus granulosus fmrfamide receptor 0.0012 0.0047 0.0063
Trichomonas vaginalis esterase, putative 0.0036 0.0308 0.1013
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.015
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.006 0.0081
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0047 0.0063
Echinococcus granulosus solute carrier family 22 0.0031 0.0254 0.0341
Toxoplasma gondii cell-cycle-associated protein kinase MAPK, putative 0.0355 0.3758 0.5667
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0012 0.0047 0.0055
Loa Loa (eye worm) hypothetical protein 0.0064 0.0614 0.0831
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0012 0.0047 0.0063
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0063
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0421 0.0495
Schistosoma mansoni chromobox protein 0.0069 0.0671 0.0901
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0042 0.0057
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0012 0.0047 0.0063
Echinococcus granulosus alpha 1A adrenergic receptor 0.0012 0.0047 0.0063
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0063
Schistosoma mansoni opsin-like receptor 0.0012 0.0047 0.0063
Echinococcus multilocularis solute carrier family 22 0.0031 0.0254 0.0299
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Schistosoma mansoni hypothetical protein 0.0064 0.0614 0.0824
Brugia malayi probable proline-trna synthetase - fission yeast, putative 0.0012 0.0053 0.0062
Brugia malayi Heterochromatin protein 1 0.0069 0.0671 0.09
Onchocerca volvulus 0.0031 0.0254 0.1099
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0047 0.0063
Onchocerca volvulus 0.0012 0.0047 0.0024
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0421 0.0565
Brugia malayi Melatonin receptor type 1A 0.0012 0.0047 0.0053
Mycobacterium tuberculosis Conserved protein 0.0036 0.0308 0.1144
Echinococcus granulosus calcium dependent protein kinase 0.0063 0.0602 0.0809
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0047 0.0055
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0042 0.0057
Brugia malayi Bifunctional aminoacyl-tRNA synthetase 0.0066 0.0632 0.0847
Loa Loa (eye worm) bifunctional aminoacyl-tRNA synthetase 0.0027 0.0212 0.0287
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.0055
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0175 0.0425
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0042 0.0049
Schistosoma mansoni cpg binding protein 0.0029 0.0229 0.0308
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Plasmodium vivax lysine--tRNA ligase, putative 0.0049 0.045 0.045
Leishmania major hypothetical protein, conserved 0.0011 0.0038 0.0504
Loa Loa (eye worm) hypothetical protein 0.0049 0.045 0.0609
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.0761
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0012 0.0047 0.0055
Trypanosoma brucei sugar transporter, putative 0.0031 0.0254 0.3381
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0042 0.0049
Brugia malayi nuclear receptor NHR-88 0.0011 0.0042 0.0047
Schistosoma mansoni hypothetical protein 0.0064 0.0614 0.0824
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2295 0.2701
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0043 0.014
Schistosoma mansoni hypothetical protein 0.0012 0.0047 0.0063
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0175 0.2338
Entamoeba histolytica protein kinase, putative 0.0067 0.0647 0.1569
Mycobacterium ulcerans sugar transporter 0.0031 0.0254 0.5639
Echinococcus granulosus Threonyl tRNA synthetase C 0.0012 0.0053 0.0072
Trypanosoma cruzi hexose transporter, putative 0.0037 0.0322 0.4296
Onchocerca volvulus 0.0031 0.0254 0.1099
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0047 0.0055
Schistosoma mansoni hypothetical protein 0.0064 0.0614 0.0824
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0042 0.0056
Schistosoma mansoni rab6-interacting 0.002 0.0132 0.0178
Mycobacterium tuberculosis Lysyl-tRNA synthetase 2 LysX 0.0042 0.037 0.1406
Schistosoma mansoni hypothetical protein 0.0139 0.1419 0.1906
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0042 0.0047
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0011 0.0043 0.0043
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0067 0.0647 0.0976
Mycobacterium ulcerans sugar-transport integral membrane protein SugI 0.0031 0.0254 0.5639
Entamoeba histolytica hypothetical protein 0.0049 0.045 0.1091
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Echinococcus granulosus lysyl tRNA synthetase 0.0049 0.045 0.0604
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.01 0.0265
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Loa Loa (eye worm) major facilitator superfamily transporter 0.0031 0.0254 0.0344
Schistosoma mansoni glucose transporter 0.0031 0.0254 0.0341
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi hypothetical protein 0.0031 0.0254 0.0334
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0656 0.8747
Schistosoma mansoni biogenic amine receptor 0.0012 0.0047 0.0063
Echinococcus granulosus geminin 0.0696 0.7445 1
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0507 0.0764
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0066 0.0632 0.0856
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0047 0.0055
Echinococcus granulosus neuropeptide FF receptor 2 0.0012 0.0047 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.014
Trypanosoma cruzi hypothetical protein, conserved 0.0011 0.0038 0.0504
Plasmodium falciparum protein kinase 7 0.062 0.663 0.663
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0012 0.0047 0.0063
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0175 0.0582
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0111 0.0309
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi F/Y-rich N-terminus family protein 0.0009 0.0014 0.0009
Entamoeba histolytica protein kinase, putative 0.0067 0.0647 0.1569
Loa Loa (eye worm) histone methyltransferase 0.0009 0.0016 0.0021
Schistosoma mansoni polycystin 1-related 0.002 0.0132 0.0178
Echinococcus multilocularis chromobox protein 2 0.0011 0.0043 0.005
Trypanosoma cruzi prolyl-tRNA synthetase, putative 0.0077 0.075 1
Schistosoma mansoni adenoreceptor 0.0012 0.0047 0.0063
Leishmania major myo-inositol/proton symporter (MIT) 0.0031 0.0254 0.3381
Schistosoma mansoni glycyl-tRNA synthetase 0.0012 0.0053 0.0072
Onchocerca volvulus 0.0031 0.0254 0.1099
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Plasmodium falciparum LCCL domain-containing protein 0.002 0.0132 0.0132
Brugia malayi putative neuropeptide receptor 0.0012 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0057
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.006 0.0081
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0011 0.0043 0.0058
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Onchocerca volvulus 0.0012 0.0047 0.0024
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0063
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0063
Echinococcus multilocularis allatostatin A receptor 0.0012 0.0047 0.0055
Echinococcus granulosus neuropeptide s receptor 0.0012 0.0047 0.0063
Onchocerca volvulus 0.0031 0.025 0.108
Onchocerca volvulus 0.002 0.0132 0.0469
Wolbachia endosymbiont of Brugia malayi prolyl-tRNA synthetase 0.0012 0.0053 0.2103
Entamoeba histolytica hypothetical protein 0.0111 0.1116 0.2706
Brugia malayi beta-lactamase family protein 0.0036 0.0308 0.0407
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trypanosoma brucei Aminoacyl-tRNA editing domain containing protein, putative 0.0011 0.0038 0.0504
Schistosoma mansoni serine/threonine protein kinase 0.0067 0.0647 0.0869
Echinococcus multilocularis dro:myosuppressin receptor 0.0012 0.0047 0.0055
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0113 0.0371
Loa Loa (eye worm) latrophilin receptor protein 2 0.0064 0.0614 0.0831
Schistosoma mansoni lipoxygenase 0.0118 0.1192 0.1601
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Schistosoma mansoni smad 0.0008 0.0007 0.001
Echinococcus granulosus glycyl tRNA synthetase 0.0012 0.0053 0.0072
Echinococcus multilocularis geminin 0.0696 0.7445 0.8762
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0042 0.0047
Echinococcus multilocularis g-protein coupled receptor 0.0012 0.0047 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0421 0.0565
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0011 0.0043 0.014
Loa Loa (eye worm) hypothetical protein 0.0203 0.2113 0.2861
Brugia malayi putative neuropeptide receptor NPR1 0.0012 0.0047 0.0053
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0047 0.0055
Onchocerca volvulus 0.0012 0.0047 0.0024
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.0834
Echinococcus multilocularis G-protein coupled receptor, putative 0.0012 0.0047 0.0055
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0308 0.1144
Mycobacterium ulcerans hypothetical protein 0.0024 0.0175 0.39
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0308 0.1144
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0126 0.0178
Echinococcus multilocularis neuropeptide FF receptor 2 0.0012 0.0047 0.0055
Schistosoma mansoni lipoxygenase 0.0082 0.0809 0.1087
Onchocerca volvulus 0.0012 0.0047 0.0024
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0042 0.0056
Trichomonas vaginalis glucose transporter, putative 0.0068 0.0656 0.2157
Brugia malayi CXXC zinc finger family protein 0.0029 0.0229 0.0301
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0113 0.0371
Echinococcus granulosus 7TM GPCR rhodopsin 0.0012 0.0047 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1969 0.6471
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0042 0.0057
Echinococcus multilocularis mothers against decapentaplegic 5 0.0008 0.0007 0.0009
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2295 0.3082
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0012 0.0047 0.0055
Onchocerca volvulus 0.0012 0.0047 0.0024
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0043 0.0104
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0175 0.39
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Echinococcus multilocularis glutamyl tRNA synthetase cytoplasmic 0.0066 0.0632 0.0744
Onchocerca volvulus 0.0012 0.0047 0.0024
Mycobacterium leprae Probable prolyl tRNA synthetase ProS 0.0066 0.0632 1
Plasmodium vivax threonine--tRNA ligase, putative 0.0012 0.0053 0.0053
Trichomonas vaginalis sugar transport protein, putative 0.0031 0.0254 0.0834
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0042 0.0047
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0042 0.0056
Brugia malayi Sugar transporter family protein 0.022 0.2295 0.3101
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0308 0.1144
Trypanosoma cruzi hexose transporter 0.0068 0.0656 0.8747
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) transcription factor SMAD2 0.0119 0.1207 0.1635
Trypanosoma brucei lysyl-tRNA synthetase, putative 0.0049 0.045 0.5996
Toxoplasma gondii facilitative glucose transporter GT1 0.022 0.2295 0.3461
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0308 0.1144
Trypanosoma brucei myo-inositol/proton symporter (MIT) 0.0031 0.0254 0.3381
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0308 0.0414
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0011 0.0043 0.0043
Echinococcus multilocularis solute carrier family 2, facilitated glucose 0.022 0.2295 0.2701
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0011 0.0043 0.0064
Brugia malayi neuropeptide F receptor 0.0012 0.0047 0.0053
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0113 0.0371
Echinococcus granulosus FTZ F1 alpha 0.0011 0.0042 0.0056
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0067 0.0647 0.0876
Echinococcus multilocularis lipoxygenase domain containing protein 0.002 0.0132 0.0156
Echinococcus granulosus solute carrier family 22 0.0031 0.0254 0.0341
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.0834
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0067 0.0647 0.0647
Onchocerca volvulus 0.0012 0.0047 0.0024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0124
Loa Loa (eye worm) glycyl-tRNA synthetase 0.0012 0.0053 0.0072
Loa Loa (eye worm) hypothetical protein 0.0036 0.0308 0.0417
Schistosoma mansoni hypothetical protein 0.002 0.0132 0.0178
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0064 0.0614 0.0824
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0018 0.0111 0.2463
Brugia malayi G-protein coupled receptor 0.0012 0.0047 0.0053
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0042 0.0047
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0012 0.0047 0.0063
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0042 0.0056
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0063
Mycobacterium ulcerans beta-lactamase 0.0036 0.0308 0.6848
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0203 0.2113 0.2861
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0042 0.0049
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0042 0.0047
Echinococcus granulosus neuropeptide receptor 0.0012 0.0047 0.0063
Brugia malayi Latrophilin receptor protein 2 0.0064 0.0614 0.0822
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1969 0.6471
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0308 0.0414
Loa Loa (eye worm) hypothetical protein 0.0024 0.0175 0.0238
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0012 0.0047 0.0063
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0126 0.0126
Mycobacterium tuberculosis Conserved protein 0.0036 0.0308 0.1144
Brugia malayi Dopamine receptor protein 2 0.0012 0.0047 0.0053
Brugia malayi Associated with TFs and helicases family protein 0.0011 0.0043 0.0048
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0289 0.3042 0.4114
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi Protein cec-1. 0.0011 0.0043 0.0048
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0042 0.0056
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0047 0.0063
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0203 0.2113 0.2854
Brugia malayi hypothetical protein 0.002 0.0132 0.0169
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0039 0.0341 0.1552
Leishmania major prolyl-tRNA synthetase, putative,bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.075 1
Mycobacterium leprae Probable lipase LipE 0.0036 0.0308 0.4546
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Echinococcus granulosus glutamyl tRNA synthetase cytoplasmic 0.0066 0.0632 0.0849
Brugia malayi bifunctional aminoacyl-tRNA synthetase 0.0066 0.0632 0.0847
Echinococcus multilocularis orexin receptor type 2 0.0012 0.0047 0.0055
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.01 0.0265
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0064 0.0614 0.0722
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0042 0.0056
Leishmania major glucose transporter/membrane transporter D2, putative 0.0068 0.0656 0.8747
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0175 0.2338
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Schistosoma mansoni neuropeptide f receptor 76f 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0126 0.0305
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Echinococcus multilocularis solute carrier family 22 0.0031 0.0254 0.0299
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0175 0.39
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0012 0.0047 0.0055
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0012 0.0047 0.0063
Mycobacterium tuberculosis Probable conserved integral membrane transport protein 0.0031 0.0254 0.0914
Onchocerca volvulus 0.0012 0.0049 0.0039
Echinococcus multilocularis neuropeptide Y receptor 0.0012 0.0047 0.0055
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0373 0.1226
Echinococcus granulosus tm gpcr rhodopsin 0.0012 0.0047 0.0063
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0008 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0308 0.0417
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0047 0.0063
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0012 0.0047 0.0055
Brugia malayi steroid hormone receptor 0.0011 0.0042 0.0047
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0011 0.0043 0.005
Chlamydia trachomatis threonine--tRNA ligase 0.0012 0.0053 0.1186
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0012 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0057
Giardia lamblia Lysyl-tRNA synthetase 0.0049 0.045 0.0974
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.006 0.0082
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0046 0.0421 0.0565
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.015
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.014
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0308 0.4105
Trichomonas vaginalis conserved hypothetical protein 0.0068 0.0656 0.2157
Leishmania major protein kinase, putative 0.0067 0.0647 0.8623
Onchocerca volvulus 0.0031 0.0254 0.1099
Echinococcus multilocularis General substrate transporter 0.0189 0.1961 0.2308
Loa Loa (eye worm) hypothetical protein 0.0036 0.0308 0.0417
Trichomonas vaginalis prolyl-tRNA synthetase, putative 0.0066 0.0632 0.2078
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0308 0.0363
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0012 0.0047 0.0063
Plasmodium falciparum mitogen-activated protein kinase 2 0.0355 0.3758 0.3758
Trypanosoma brucei bifunctional aminoacyl-tRNA synthetase, putative 0.0077 0.075 1
Echinococcus multilocularis Polycystic kidney disease protein 0.002 0.0132 0.0156
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0066 0.0632 0.0856
Brugia malayi glycyl-tRNA synthetase 0.0012 0.0053 0.0062
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0012 0.0047 0.0063
Plasmodium falciparum heterochromatin protein 1 0.0011 0.0043 0.0043
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.0834
Trichomonas vaginalis glucose transporter, putative 0.0031 0.0254 0.0834
Trichomonas vaginalis threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0175
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0126 0.0148
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.045 0.0604
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0126 0.0414
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0042 0.0056
Onchocerca volvulus 0.0031 0.0254 0.1099
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0126 0.4961
Echinococcus multilocularis Smad4 0.0008 0.0007 0.0009
Loa Loa (eye worm) hypothetical protein 0.0011 0.0043 0.0058
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Schistosoma mansoni myosin xvIII 0.0012 0.0047 0.0063
Plasmodium falciparum calcium-dependent protein kinase 3 0.0067 0.0647 0.0647
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0047 0.0055
Onchocerca volvulus 0.0012 0.0047 0.0024
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0656 0.8747
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0132 0.0178
Echinococcus granulosus somatostatin receptor 0.0012 0.0047 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1969 0.6471
Trypanosoma cruzi hexose transporter, putative 0.0031 0.0254 0.3381
Entamoeba histolytica hypothetical protein 0.0011 0.0043 0.0104
Mycobacterium ulcerans lysyl-tRNA synthetase 0.0049 0.045 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0042 0.0047
Loa Loa (eye worm) Smad1 0.0008 0.0007 0.001
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0057
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0012 0.0047 0.0063
Brugia malayi hypothetical protein 0.002 0.0132 0.0169
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2295 0.3082
Trichomonas vaginalis glucosylceramidase, putative 0.02 0.2079 0.6833
Schistosoma mansoni glucose transport protein 0.022 0.2295 0.3082
Loa Loa (eye worm) follicle stimulating hormone receptor 0.069 0.7384 1
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0793 0.8497 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Schistosoma mansoni opsin-like receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0036 0.0308 0.0417
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0042 0.0056
Loa Loa (eye worm) MH1 domain-containing protein 0.0008 0.0007 0.001
Echinococcus granulosus serotonin receptor 0.0012 0.0047 0.0063
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0049 0.045 0.1479
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2295 0.3082
Mycobacterium ulcerans lipase LipD 0.0036 0.0308 0.6848
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.015
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0046 0.0421 0.0495
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0042 0.0049
Loa Loa (eye worm) hypothetical protein 0.0018 0.0111 0.015
Entamoeba histolytica Rad52/22 family double-strand break repair protein, putative 0.0111 0.1116 0.2706
Onchocerca volvulus 0.0012 0.0047 0.0024
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0042 0.0049
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0308 0.1013
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0042 0.0056
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.0869
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0118 0.1192 0.1601
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.0055
Schistosoma mansoni cpg binding protein 0.003 0.0247 0.0332
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0024 0.0175 0.2315
Onchocerca volvulus 0.0024 0.0175 0.0693
Schistosoma mansoni protein kinase 0.0067 0.0647 0.0869
Echinococcus multilocularis neuropeptide receptor 0.0012 0.0047 0.0055
Schistosoma mansoni rab6-interacting 0.002 0.0132 0.0178
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0113 0.0371
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0218 0.0716
Loa Loa (eye worm) threonyl-tRNA synthetase 0.0012 0.0053 0.0072
Echinococcus granulosus neuropeptide Y receptor 0.0012 0.0047 0.0063
Brugia malayi MH2 domain containing protein 0.0119 0.1207 0.1626
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Brugia malayi chromobox protein homolog 3 0.0039 0.0341 0.0452
Chlamydia trachomatis lysine--tRNA ligase 0.0049 0.045 1
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0067 0.0647 0.0867
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0126 0.016
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0218 0.0716
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0057
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0308 0.1013
Schistosoma mansoni hypothetical protein 0.0064 0.0614 0.0824
Echinococcus granulosus sex peptide receptor 0.0012 0.0047 0.0063
Mycobacterium ulcerans hypothetical protein 0.0036 0.0308 0.6848
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0012 0.0047 0.0055
Onchocerca volvulus 0.0031 0.0254 0.1099
Echinococcus granulosus synaptic vesicle 2 protein 0.0031 0.0254 0.0341
Schistosoma mansoni hypothetical protein 0.0012 0.0047 0.0063
Onchocerca volvulus 0.0031 0.0254 0.1099
Trypanosoma cruzi hexose transporter, putative 0.0068 0.0656 0.8747
Schistosoma mansoni hypothetical protein 0.022 0.2295 0.3082
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0632 0.0849
Onchocerca volvulus 0.0031 0.0254 0.1099
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.014
Brugia malayi AKH receptor 0.0012 0.0047 0.0053
Onchocerca volvulus 0.0011 0.0043 0.0004
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0126 0.7341
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0254 0.0334
Plasmodium falciparum hexose transporter 0.022 0.2295 0.2295
Brugia malayi Dopamine receptor protein 1 0.0012 0.0047 0.0053
Brugia malayi follicle stimulating hormone receptor 0.069 0.7384 1
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0111 0.0111
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0011 0.0043 0.0058
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0308 0.6848
Brugia malayi neuropeptide F receptor 0.0012 0.0047 0.0053
Onchocerca volvulus 0.0012 0.0047 0.0024
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi SET domain containing protein 0.0012 0.0049 0.0057
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0043 0.0104
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.2401 1
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0043 0.005
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1969 0.6471
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0012 0.0047 0.0053
Trypanosoma brucei glucose transporter, putative 0.0068 0.0656 0.8747
Mycobacterium ulcerans prolyl-tRNA synthetase 0.0023 0.0171 0.3811
Trypanosoma cruzi sugar transporter, putative 0.0031 0.0254 0.3381
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0175 0.2338
Trypanosoma brucei glucose transporter, putative 0.0068 0.0656 0.8747
Toxoplasma gondii sugar transporter ST1 0.0031 0.0254 0.0383
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Mycobacterium tuberculosis Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase) 0.0012 0.0053 0.0066
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Schistosoma mansoni neuropeptide receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0068 0.0656 0.2157
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.3042 1
Loa Loa (eye worm) MH2 domain-containing protein 0.0119 0.1207 0.1635
Onchocerca volvulus 0.0031 0.0254 0.1099
Giardia lamblia Sugar-proton symporter 0.0031 0.0254 0.0492
Echinococcus multilocularis chromobox protein 1 0.0069 0.0671 0.079
Echinococcus granulosus Smad4 0.0008 0.0007 0.001
Echinococcus multilocularis neuropeptide s receptor 0.0012 0.0047 0.0055
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2295 0.2701
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0042 0.0047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0043 0.014
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0009 0.0016 0.0021
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0308 0.0414
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0175 0.0228
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.0869
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0046 0.0421 0.057
Schistosoma mansoni biogenic amine receptor 0.0012 0.0047 0.0063
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.2421 0.2849
Schistosoma mansoni hypothetical protein 0.0047 0.043 0.0577
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0308 0.1013
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0012 0.0047 0.0055
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0038 0.0124
Schistosoma mansoni ap endonuclease 0.0019 0.0126 0.0169
Echinococcus granulosus General substrate transporter 0.0189 0.1961 0.2634
Trichomonas vaginalis myo-inositol transporter, putative 0.0031 0.0254 0.0834
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0042 0.0057
Schistosoma mansoni Smad4 0.0008 0.0007 0.001
Plasmodium vivax multidomain scavenger receptor, putative 0.002 0.0132 0.0132
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0012 0.0047 0.0055
Echinococcus granulosus Chromo domain 0.0011 0.0043 0.0057
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.043 0.0573
Loa Loa (eye worm) beta-lactamase 0.0036 0.0308 0.0417
Trypanosoma brucei glycyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Onchocerca volvulus Neuropeptide F receptor homolog 0.0012 0.0047 0.0024
Echinococcus granulosus dnaJ subfamily B 0.0408 0.4331 0.5817
Trypanosoma brucei threonyl-tRNA synthetase, putative 0.0012 0.0053 0.0711
Plasmodium vivax sugar transporter, putative 0.0031 0.0254 0.0254
Schistosoma mansoni smad1 5 8 and 0.0008 0.0007 0.001
Toxoplasma gondii glycyl-tRNA synthetase 0.0012 0.0053 0.008
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0126 0.1677
Leishmania major hypothetical protein, conserved 0.0011 0.0038 0.0504
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0042 0.0057
Echinococcus granulosus neuropeptide receptor A26 0.0012 0.0047 0.0063
Trypanosoma brucei THT1 - hexose transporter, putative 0.0068 0.0656 0.8747
Entamoeba histolytica glycyl-tRNA synthetase, putative 0.0012 0.0053 0.0129
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0047 0.0063
Schistosoma mansoni sugar transporter 0.0031 0.0254 0.0341
Brugia malayi Doublecortin family protein 0.002 0.0132 0.0169
Entamoeba histolytica hypothetical protein 0.0011 0.0043 0.0104
Loa Loa (eye worm) hypothetical protein 0.0011 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0053 0.0072
Echinococcus multilocularis lysyl tRNA synthetase 0.0049 0.045 0.0529
Schistosoma mansoni glutamyl-tRNA synthetase cytoplasmic (glutamate--tRNA ligase) (glurs) 0.0066 0.0632 0.0849
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0254 0.0334
Onchocerca volvulus 0.0031 0.0254 0.1099
Loa Loa (eye worm) helicase 0.0011 0.0043 0.0058
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0011 0.0043 0.0057
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0063
Echinococcus granulosus Chromobox protein 3 0.0011 0.0043 0.0057
Schistosoma mansoni hypothetical protein 0.0696 0.7445 1
Trichomonas vaginalis chromobox protein, putative 0.0042 0.0373 0.1226
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0012 0.0047 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0042 0.0047
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0015 0.008 0.0264
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Echinococcus granulosus Polycystic kidney disease protein 0.002 0.0132 0.0178
Onchocerca volvulus Glucosylceramidase homolog 0.0189 0.1969 1
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0308 0.4105
Loa Loa (eye worm) hypothetical protein 0.0031 0.0254 0.0344
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0012 0.0047 0.0055
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0047 0.0055
Toxoplasma gondii prolyl-tRNA synthetase (ProRS) 0.0077 0.075 0.1132
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0012 0.0047 0.0063
Echinococcus granulosus chromobox protein 1 0.0069 0.0671 0.0901
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Brugia malayi major facilitator superfamily protein 0.0031 0.0254 0.0334
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0042 0.0056
Entamoeba histolytica prolyl-tRNA synthetase, putative 0.0066 0.0632 0.1533
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0042 0.0056
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0012 0.0047 0.0055
Schistosoma mansoni opsin-like receptor 0.0012 0.0047 0.0063
Echinococcus granulosus Sugar transporter ERD6 protein 0.0031 0.0254 0.0341
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0126 0.0126
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.0055
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0042 0.0056
Echinococcus multilocularis sex peptide receptor 0.0012 0.0047 0.0055
Echinococcus multilocularis chromobox protein 1 0.0069 0.0671 0.079
Trypanosoma brucei glucose transporter, putative 0.0068 0.0656 0.8747
Loa Loa (eye worm) heterochromatin protein 1 0.0069 0.0671 0.0909
Leishmania major lysyl-tRNA synthetase, putative 0.0049 0.045 0.5996
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0012 0.0047 0.0063
Schistosoma mansoni coup transcription factor 0.0011 0.0042 0.0056
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Brugia malayi hypothetical protein 0.0231 0.2421 0.3272
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.014
Brugia malayi G protein-coupled receptor F59B2.13 0.0012 0.0047 0.0053
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0308 0.1013
Plasmodium falciparum proline--tRNA ligase 0.0077 0.075 0.075
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0175 0.0228
Onchocerca volvulus 0.0012 0.0047 0.0024
Schistosoma mansoni protein kinase 0.0067 0.0647 0.0869
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0042 0.0057
Loa Loa (eye worm) hypothetical protein 0.0231 0.2421 0.3279
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0042 0.0049
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Schistosoma mansoni sugar transporter 0.0031 0.0254 0.0341
Echinococcus granulosus neuropeptide receptor 0.0012 0.0047 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0189 0.1969 0.6471
Mycobacterium ulcerans hypothetical protein 0.0011 0.0038 0.0841
Brugia malayi Calcitonin receptor-like protein seb-1 0.0203 0.2113 0.2854
Wolbachia endosymbiont of Brugia malayi threonyl-tRNA synthetase 0.0012 0.0053 0.2103
Brugia malayi Major Facilitator Superfamily protein 0.0031 0.0254 0.0334
Mycobacterium ulcerans glycyl-tRNA synthetase 0.0012 0.0053 0.1186
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Schistosoma mansoni sugar transporter 0.0031 0.0254 0.0341
Toxoplasma gondii transporter, major facilitator family protein 0.0031 0.0254 0.0383
Treponema pallidum prolyl-tRNA synthetase 0.0023 0.0171 1
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0042 0.0049
Loa Loa (eye worm) hypothetical protein 0.0011 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi hypothetical protein 0.0011 0.0043 0.0048
Onchocerca volvulus 0.0031 0.0254 0.1099
Trypanosoma brucei glucose transporter, putative 0.0068 0.0656 0.8747
Schistosoma mansoni lysyl-tRNA synthetase 0.0049 0.045 0.0604
Brugia malayi GnHR receptor homolog 0.0012 0.0047 0.0053
Trypanosoma brucei glucose transporter 2A 0.0068 0.0656 0.8747
Echinococcus granulosus 7tm_1 domain containing protein 0.0012 0.0047 0.0063
Trichomonas vaginalis chromobox protein, putative 0.0069 0.0671 0.2206
Echinococcus multilocularis synaptic vesicle 2 protein 0.0031 0.0254 0.0299
Mycobacterium ulcerans fusion protein of transposase for IS2606 and sialic acid-transport integral membrane protein NanT 0.0031 0.0254 0.5639
Toxoplasma gondii lysine-tRNA ligase 0.0049 0.045 0.0679
Loa Loa (eye worm) neuropeptide F receptor 0.0012 0.0047 0.0063
Echinococcus granulosus cpg binding protein 0.003 0.0247 0.0332
Onchocerca volvulus 0.0012 0.0047 0.0024
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.01 0.0265
Loa Loa (eye worm) hypothetical protein 0.0024 0.0175 0.0238
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0175 0.0425
Loa Loa (eye worm) hypothetical protein 0.0067 0.0647 0.0876
Schistosoma mansoni smad1 5 8 and 0.0008 0.0007 0.001
Plasmodium falciparum calcium-dependent protein kinase 1 0.0067 0.0647 0.0647
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus granulosus lipoxygenase domain containing protein 0.002 0.0132 0.0178
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0229 0.0311
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0067 0.0647 0.0976
Brugia malayi ecdysteroid receptor 0.0011 0.0042 0.0047
Brugia malayi ORL1-like opioid receptor 0.0012 0.0047 0.0053
Echinococcus granulosus biogenic amine 5HT receptor 0.0012 0.0047 0.0063
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0012 0.0047 0.0053
Treponema pallidum threonyl-tRNA synthetase 0.0012 0.0053 0.3113
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.3042 1
Loa Loa (eye worm) hypothetical protein 0.0011 0.0042 0.0057
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0067 0.0647 0.0869
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0042 0.0047
Trichomonas vaginalis lysyl-tRNA synthetase, putative 0.0043 0.0385 0.1264
Loa Loa (eye worm) melatonin receptor type 1A 0.0012 0.0047 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Loa Loa (eye worm) hypothetical protein 0.0011 0.0043 0.0058
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Schistosoma mansoni hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi Dopamine receptor 0.0012 0.0047 0.0053
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.2421 0.3252
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0118 0.1192 0.1403
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0308 0.0308
Trichomonas vaginalis conserved hypothetical protein 0.0011 0.0043 0.014
Schistosoma mansoni neuropeptide F-like receptor 0.0012 0.0047 0.0063
Trichomonas vaginalis glucosylceramidase, putative 0.0289 0.3042 1
Schistosoma mansoni hypothetical protein 0.0011 0.0043 0.0057
Loa Loa (eye worm) G-protein coupled receptor 0.0012 0.0047 0.0063
Plasmodium falciparum major facilitator superfamily domain-containing protein, putative 0.0031 0.0254 0.0254
Plasmodium falciparum calcium-dependent protein kinase 5 0.0067 0.0647 0.0647
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0111 0.0111
Mycobacterium leprae Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase) (ThrRS) (Threonine-tRNA ligase) 0.0012 0.0053 0.0262
Echinococcus multilocularis GPCR, family 2 0.0064 0.0614 0.0722
Plasmodium vivax hexose transporter 0.022 0.2295 0.2295
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.01 0.0265
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0175 0.0228
Echinococcus granulosus peptide allatostatin:somatostatin 0.0012 0.0047 0.0063
Brugia malayi lysyl-tRNA synthetase 0.0049 0.045 0.06
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0042 0.0056
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0175 0.39
Onchocerca volvulus 0.0036 0.0308 0.1381
Echinococcus granulosus neuropeptides capa receptor 0.0012 0.0047 0.0063
Schistosoma mansoni hypothetical protein 0.0696 0.7445 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0042 0.0056
Onchocerca volvulus 0.0012 0.0047 0.0024
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0012 0.0047 0.0055
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Echinococcus granulosus dro:myosuppressin receptor 0.0012 0.0047 0.0063
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0018 0.0113 0.0371
Echinococcus multilocularis neuropeptides capa receptor 0.0012 0.0047 0.0055
Echinococcus granulosus solute carrier family 22 0.0031 0.0254 0.0341
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0011 0.0043 0.0057
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0042 0.0056
Echinococcus granulosus g protein coupled receptor 0.0012 0.0047 0.0063
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0012 0.0047 0.0063
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Echinococcus granulosus g protein coupled receptor 0.0012 0.0047 0.0063
Echinococcus granulosus GPCR family 2 0.0064 0.0614 0.0824
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0308 0.0417
Echinococcus granulosus rhodopsin orphan GPCR 0.0012 0.0047 0.0063
Brugia malayi Valyl-tRNA synthetase 0.0011 0.0043 0.0048
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0126 0.0414
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Brugia malayi G protein-coupled receptor 0.0012 0.0047 0.0053
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Echinococcus multilocularis glycyl tRNA synthetase 0.0012 0.0053 0.0063
Onchocerca volvulus 0.0031 0.0254 0.1099
Echinococcus granulosus solute carrier family 2 facilitated glucose 0.022 0.2295 0.3082
Plasmodium vivax proline--tRNA ligase, putative 0.0077 0.075 0.075
Schistosoma mansoni chromobox protein 0.0011 0.0043 0.0057
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0042 0.0047
Plasmodium vivax mitogen-activated protein kinase 2, putative 0.0355 0.3758 0.3758
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0308 0.1144
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0067 0.0647 0.8623
Leishmania major hypothetical protein, conserved 0.0031 0.0254 0.3381
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0126 0.017
Loa Loa (eye worm) hypothetical protein 0.002 0.0132 0.0179
Brugia malayi nuclear hormone receptor 0.0011 0.0042 0.0047
Mycobacterium tuberculosis Lysyl-tRNA synthetase 1 LysS (lysine--tRNA ligase 1) (LysRS 1) (lysine translase) 0.0042 0.037 0.1406
Brugia malayi Serotonin receptor 0.0012 0.0047 0.0053
Echinococcus multilocularis fmrfamide receptor 0.0012 0.0047 0.0055
Schistosoma mansoni protein kinase 0.0067 0.0647 0.0869
Schistosoma mansoni biogenic amine receptor 0.0012 0.0047 0.0063
Brugia malayi hypothetical protein 0.0012 0.0047 0.0053
Toxoplasma gondii sugar transporter ST2 0.0031 0.0254 0.0383
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0011 0.0043 0.0064
Trichomonas vaginalis sugar transporter, putative 0.0031 0.0254 0.0834
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0011 0.0043 0.0104
Echinococcus multilocularis solute carrier family 2 facilitated glucose 0.022 0.2295 0.2701
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0126 0.1677
Echinococcus granulosus hypothetical protein 0.0012 0.0047 0.0063
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0042 0.0056
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0067 0.0647 0.0647
Brugia malayi hypothetical protein 0.0031 0.0254 0.0334
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0018 0.0113 0.0371
Echinococcus multilocularis rhodopsin orphan GPCR 0.0012 0.0047 0.0055
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0046 0.0421 0.0565
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0012 0.0047 0.0063
Loa Loa (eye worm) hypothetical protein 0.0012 0.0047 0.0063
Trichomonas vaginalis conserved hypothetical protein 0.0015 0.008 0.0264
Mycobacterium ulcerans integral membrane transport protein 0.0031 0.0254 0.5639
Onchocerca volvulus 0.0012 0.0047 0.0024
Echinococcus multilocularis g protein coupled receptor 0.0012 0.0047 0.0055
Schistosoma mansoni chromobox protein 0.0069 0.0671 0.0901
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0254 0.0834
Schistosoma mansoni amine GPCR 0.0012 0.0047 0.0063
Schistosoma mansoni growth hormone secretagogue receptor 0.0012 0.0047 0.0063

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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